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Data updated: May 24, 2026

ALNYLAM PHARMS INC

Pharma
Gastroenterology Execution: Good

ALNYLAM PHARMS INC is a pharmaceutical company focused on Gastroenterology. Key products include AMVUTTRA.

2018
Since
4
Drugs
-
Trials
0
New Drugs (2yr)
Modality:
4 Small Molecules
Novel Drugs (2018-2022):
4 Novel Approvals 3 First-in-Class 4 Orphan Drug 3 Breakthrough

ALNYLAM PHARMS INC at a Glance

  • Growing R&D activity with 17 trials in last 2 years
  • Fast trial execution (28 months median completion)

Recent FDA Approvals

New drug approvals (NDA/BLA) in the last 2 years. Shows novel drugs only, excluding generics and label supplements.

No recent approvals

Therapeutic Areas

Disease areas where this company has approved drugs and active pipeline. Weighted by commercial stage: approved drugs count most, followed by late-stage trials.

Gastroenterology 100%
1 drugs

Pipeline Snapshot

Active clinical trials across all therapeutic areas. Data from ClinicalTrials.gov.

No active pipeline data available

Phase 3 Readout Calendar Pro

4 Phase 3 trials with confidence-graded primary completion dates.

Full calendar →
Q4 2027
Nucresiran
Hereditary Transthyretin-Mediated Amyloidosis With Polyneuropathy
Estimated · fresh NCT07223203
Q1 2028
Vutrisiran
Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Estimated · fresh NCT06679946
Q2 2030
Nucresiran
Transthyretin Amyloidosis With Cardiomyopathy
Estimated · fresh NCT07052903
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Anchored on CT.gov primary completion date. Topline announcements typically precede this by 3–9 months. Confidence labels combine date type (ACTUAL/ESTIMATED) with last-update freshness.

Pro Intelligence Preview

Deep insights for investors and analysts

Revenue Insights

  • AMVUTTRA leads revenue
  • 4 key drugs tracked
View revenue breakdown →

Trial Catalysts

  • Gastroenterology pipeline focus
  • 4 Phase 3 readouts tracked
View readout calendar →

Patent Risk

  • Patent expiration timeline
  • Revenue at risk analysis
View patent timeline →

Compare Companies

  • Side-by-side pipeline analysis
  • Revenue & market share comparison
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Execution Intelligence

  • Phase 3: 10/15 completed
  • Speed: 28 months avg
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Revenue forecasts • Trial milestones • Patent risk modeling

How We Calculate These Metrics

Execution Quality Score

Measures trial completion rates weighted by phase importance. Phase 3 trials count 4x more than Phase 1 because late-stage completion is harder and more valuable.

What counts as "completed": A trial that reached its planned endpoint and reported results. Trials that were terminated early, withdrawn, or suspended are not counted as completed—these often indicate safety issues, lack of efficacy, or strategic pivots.

  • Excellent (80%+): Top-tier execution, most trials reach planned endpoints
  • Good (60-79%): Strong execution with occasional early terminations
  • Fair (40-59%): Average execution, notable rate of terminated/withdrawn trials
  • Needs Improvement (under 40%): High termination rates, execution challenges