Metabolic Drugs

345 FDA-approved drugs

TheraRadar tracks 345 FDA-approved metabolic drugs from 135 companies across 30 drug classes, led by Novo Nordisk, with 1,453 active clinical trials in the pipeline. Explore recent approvals, top companies, active trials by indication, and drug classes for Metabolic.

Upcoming Metabolic Phase 3 readouts →

Metabolic Approvals by Year

10

'15

10

'16

14

'17

2

'18

15

'19

6

'20

9

'21

8

'22

10

'23

7

'24

9

'25

7

'26

Recent Metabolic Drug Approvals

Dapagliflozin tablets are indicated: To reduce the risk of hospitalization for heart failure in adul...

DAPAGLIFLOZIN AND METFORMIN HYDROCHLORIDE

Dapagliflozin and metformin HCl extended-release tablets are a combination of dapagliflozin and metf...

DAPAGLIFLOZIN AND SAXAGLIPTIN HYDROCHLORIDE

Dapagliflozin and saxagliptin tablets are indicated as an adjunct to diet and exercise to improve gl...

ORFORGLIPRON CALCIUM

FOUNDAYO TM is indicated in combination with a reduced-calorie diet and increased physical activity ...

AWIQLI FLEXTOUCH

Awiqli is indicated as an adjunct to diet and exercise to improve glycemic control in adults with ty...

DESMOPRESSIN ACETATE

nephrogenic diabetes insipidus...

SITAGLIPTIN PHOSPHATE

SITAGLIPTIN PHOSPHATE

Sitagliptin tablets are indicated as an adjunct to diet and exercise to improve glycemic control in ...

LERODALCIBEP-LIGA

LEROCHOL TM is indicated as an adjunct to diet and exercise to reduce low-density lipoprotein choles...

LIB THERAPEUTICS, INC.

PLOZASIRAN SODIUM

REDEMPLO is indicated as an adjunct to diet to reduce triglycerides in adults with familial chylomic...

AFLIBERCEPT-BOAV

INSULIN ASPART-XJHZ

KIRSTY is indicated to improve glycemic control in adults and pediatric patients with diabetes melli...

BIOCON BIOLOGICS INC

SITAGLIPTIN AND METFORMIN HYDROCHLORIDE

SITAGLIPTIN AND METFORMIN HYDROCHLORIDE

Aurobindo Pharma

INSULIN ASPART-SZJJ

MERILOG is indicated to improve glycemic control in adults and pediatric patients with diabetes mell...

SANOFI-AVENTIS U.S. LLC

MERILOG SOLOSTAR

INSULIN ASPART-SZJJ

MERILOG is indicated to improve glycemic control in adults and pediatric patients with diabetes mell...

SANOFI-AVENTIS U.S. LLC

SITAGLIPTIN HYDROCHLORIDE

1 INDICATIONS & USAGE BRYNOVIN is indicated as an adjunct to diet and exercise to improve glycemic c...

Liraglutide injection is indicated: as an adjunct to diet and exercise to improve glycemic control i...

TRYNGOLZA (AUTOINJECTOR)

OLEZARSEN SODIUM

TRYNGOLZA is indicated as an adjunct to diet to reduce triglycerides in adults with familial chylomi...

IONIS PHARMS INC

EXENATIDE SYNTHETIC

EXENATIDE SYNTHETIC

AFLIBERCEPT-AYYH

patients with: Neovascular (Wet) Age-Related Macular Degeneration (AMD) ( 1...

VEGFVEGF-AVEGFR

Showing the 20 most recent of 345 metabolic drugs. View all 345 →

Top Metabolic Companies

Novo Nordisk 31 Eli Lilly 28 Teva 14 Novartis 11 Merck 11 Takeda 11 AstraZeneca 10 Sanofi 10 Pfizer 10 Boehringer Ingelheim 8

Metabolic Active Trials by Indication

1,453 active trials — the forward pipeline, not just approvals.

Obesity 524 Type 2 Diabetes 292 Diabetes (General) 194 Type 1 Diabetes 127 NASH/NAFLD 118 Diabetic Complications 108 Dyslipidemia 90

All competitive landscapes →

Metabolic Drug Classes

Insulin Analog 24

Sodium-Glucose Cotransporter 2 Inhibitor 9

Dipeptidyl Peptidase 4 Inhibitor 9

GLP-1 Receptor Agonist 8

Sulfonylurea 8

Glucose-dependent Insulinotropic Polypeptide Receptor Agonist 6

Alkaloid 5

Bile Acid Sequestrant 5

Vascular Endothelial Growth Factor Inhibitor 4

HMG-CoA Reductase Inhibitor 4

Metabolic at a Glance

Total Drugs: 345
Companies: 135
Drug Classes: 30
Active Trials: 1,453
Latest Approval: 2026-04-14