CNS Drugs
863 FDA-approved drugs
TheraRadar tracks 863 FDA-approved cns drugs from 293 companies across 48 drug classes, led by Teva, with 2,271 active clinical trials in the pipeline. Explore recent approvals, top companies, active trials by indication, and drug classes for CNS.
CNS Approvals by Year
20
'15
13
'16
16
'17
22
'18
28
'19
15
'20
22
'21
23
'22
22
'23
23
'24
16
'25
2
'26
Recent CNS Drug Approvals
SOLRIAMFETOL
SOLRIAMFETOL
2026-10-06
UNICHEM
BYSANTI
MILSAPERIDONE
2026-02-20
VANDA PHARMS INC
NEREUS
TRADIPITANT
the prevention of vomiting induced by motion in adults...
2025-12-30
VANDA PHARMS INC
DAYBUE STIX
TROFINETIDE
Rett syndrome in adults and pediatric patients 2 years of age and older...
2025-12-11
ACADIA PHARMS INC
DIROXIMEL FUMARATE
DIROXIMEL FUMARATE
relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remit...
2025-11-12
ZYDUS
Nicotinic acid receptorNrf2
SUBVENITE
LAMOTRIGINE
conversion to monotherapy in adults (aged 16 years and older) with partial-onset seizures who are re...
2025-09-16
OWP PHARMS
Voltage-sensitive sodium channels
ESCITALOPRAM
ESCITALOPRAM OXALATE
2025-08-29
ALMATICA
LEQEMBI IQLIK
LECANEMAB-IRMB
Alzheimer’s disease...
2025-08-29
EISAI INC
Amyloid beta
TONMYA
CYCLOBENZAPRINE HYDROCHLORIDE
fibromyalgia in adults...
2025-08-15
TONIX
ARYNTA
LISDEXAMFETAMINE DIMESYLATE
( 1 ): Attention Deficit Hyperactivity Disorder (ADHD) in adults and pediatric patients 6 years and ...
2025-06-16
AZURITY
PERAMPANEL
PERAMPANEL
partial-onset seizures with or without secondarily generalized seizures in patients with epilepsy 4 ...
2025-05-23
TARO
AMPA receptor
BREKIYA (AUTOINJECTOR)
DIHYDROERGOTAMINE MESYLATE
the acute treatment of migraine with or without aura and the acute treatment of cluster headaches in...
2025-05-14
AMNEAL
ATZUMI
DIHYDROERGOTAMINE MESYLATE
the acute treatment of migraine with or without aura in adults...
2025-04-30
SATSUMA PHARMS
5-HT 1Dα5-HT 1Dβ
SIPONIMOD
SIPONIMOD
2025-04-22
Dr. Reddy's
MEZOFY
ARIPIPRAZOLE
2025-04-15
CMG PHARM CO LTD
BUCAPSOL
BUSPIRONE HYDROCHLORIDE
the management of anxiety disorders or the short-term relief of the symptoms of anxiety...
2025-03-13
EPIC PHARMA LLC
ONAPGO
APOMORPHINE HYDROCHLORIDE
motor fluctuations in adults with advanced Parkinson's disease...
2025-02-03
MDD US
SYMBRAVO
MELOXICAM
cluster headache...
2025-01-30
AXSOME
DEUTETRABENAZINE
DEUTETRABENAZINE
2024-12-26
Aurobindo Pharma
ONTRALFY
TIZANIDINE HYDROCHLORIDE
spasticity in adults...
2024-12-12
FIDELITY BIOPHARMA
alpha-2-adrenergic receptor
Showing the 20 most recent of 863 cns drugs. View all 863 →
Top CNS Companies
CNS Active Trials by Indication
2,271 active trials — the forward pipeline, not just approvals.
Alzheimer's Disease 386 Major Depression 363 Parkinson's Disease 197 Multiple Sclerosis 194 Schizophrenia 126 Opioid Use Disorder 125 Alcohol Use Disorder 112 ALS 100
All competitive landscapes → CNS Drug Classes
Anti-epileptic Agent 22
Atypical Antipsychotic 20
Benzodiazepine 16
Osmotic Diuretic 13
Central Nervous System Stimulant 12
Catechol-O-Methyltransferase Inhibitor 10
Aromatic Amino Acid Decarboxylation Inhibitor 7
Acetylcholine Release Inhibitor 7
Mood Stabilizer 7
Radioactive Diagnostic Agent 5
CNS at a Glance
- Total Drugs
- 863
- Companies
- 293
- Drug Classes
- 48
- Active Trials
- 2,271
- Latest Approval
- 2026-10-06