Coronary Artery Disease Clinical Trial Landscape
Data updated: May 20, 2026
1,053 clinical trials tracked since 2008
Coronary Artery Disease (CAD) occurs when the heart's arteries become narrowed or blocked, often due to a buildup of plaque. This can lead to chest pain, shortness of breath, and increased risk of heart attack, affecting a significant portion of the global population. As of 2008, 1,044 clinical trials have been registered for CAD, with 158 trials currently active, meaning they are recruiting, enrolling, or active but not recruiting. The distribution of these active trials across phases reveals a substantial focus on Phase 4 studies, with 86 active trials, compared to 38 in Phase 3, 34 in Phase 2, and 9 in Phase 1. Novartis leads industry sponsorship of active trials with 3, followed by XyloCor Therapeutics, Inc. and Beijing Inno Medicine Co., Ltd., each sponsoring 2 active trials. Bayer and Roche each have 1 active trial in the CAD space. The high number of Phase 4 trials suggests a strong emphasis on post-market studies and long-term outcomes in the current CAD clinical trial landscape.
161 active
/
1053 total (since 2008)
9
Phase 1 Active
112 total
35
Phase 2 Active
238 total
39
Phase 3 Active
235 total
87
Phase 4 Active
523 total
Top Industry Sponsors
Sorted by active Active Done Failed
Novartis 3 6 2
XyloCor Therapeutics, Inc. 2 1 0
Beijing Inno Medicine Co., Ltd. 2 0 0
Bayer 1 7 2
Roche 1 7 0
+ 10 more sponsors — see full table below
Featured Phase 3 Trials
NCT07582835 RECRUITING
Study of the Long-term Effects of P2Y12 Inhibitor Monotherapy and Coagulation Markers After Percutaneous Coronary Angioplasty.
Cardiocentro Ticino n=355
NCT05427084 RECRUITING
Canagliflozin Targeting Vascular Inflammation
Ottawa Heart Institute Research Corporation n=24
NCT07102628 RECRUITING
Evaluation of Efficacy and Safety of Early in Hospital Initiation of Inclisiran Treatment in Patients With Acute Coronary Syndromes
Novartis Pharmaceuticals n=300
NCT05360446 ACTIVE NOT RECRUITING
Coronary Computed Tomography Study to Assess the Effect of Inclisiran in Addition to Maximally Tolerated Statin Therapy on Atherosclerotic Plaque Progression in Participants With a Diagnosis of Non-obstructive Coronary Artery Disease Without Previous Cardiovascular Events
Novartis Pharmaceuticals n=610
NCT06305559 ACTIVE NOT RECRUITING
A CCTA Imaging Trial to Evaluate the Effect of Obicetrapib/Ezetimibe on Coronary Plaque
NewAmsterdam Pharma n=300
+ 230 more Phase 3 trials — see full database below
Coronary Artery Disease — Trials Started by Year (last 10 years)
2016 42
2017 33
2018 43
2019 35
2020 26
2021 44
2022 25
2023 31
2024 43
2025 45
2026 27
TheraRadar.com
Full Trial Database
Complete sponsor table, every trial across all phases, plus competitive analytics. Sortable, filterable, exportable for Pro users.
Top Sponsors (all-time)
Novartis 11
XyloCor Therapeutics, Inc. 3
Beijing Inno Medicine Co., Ltd. 2
Bayer 10
Roche 8
Sinotau Pharmaceutical Group 5
Jiangsu vcare pharmaceutical technology co., LTD 5
ECRI bv 4
GE Healthcare 3
Tasly Pharmaceuticals, Inc. 3
Active Trials by Phase
Phase 1 9
Phase 2 35
Phase 3 39
Phase 4 87
Enrollment Size Distribution
1-50 283
51-200 366
201-500 154
501-1k 65
1k+ 146
All Industry Sponsors
Sorted by active Active Done Failed
Novartis 3 6 2
XyloCor Therapeutics, Inc. 2 1 0
Beijing Inno Medicine Co., Ltd. 2 0 0
Bayer 1 7 2
Roche 1 7 0
Sinotau Pharmaceutical Group 1 3 1
Jiangsu vcare pharmaceutical technology co., LTD 1 4 0
ECRI bv 1 1 2
GE Healthcare 1 2 0
Tasly Pharmaceuticals, Inc. 1 2 0
Shaanxi Micot Pharmaceutical Technology Co., Ltd. 1 0 2
Abcentra 1 1 0
DalCor Pharmaceuticals 1 1 0
Cell>Point LLC 1 1 0
Elixir Medical Corporation 1 1 0
NCT07582835 RECRUITING
Study of the Long-term Effects of P2Y12 Inhibitor Monotherapy and Coagulation Markers After Percutaneous Coronary Angioplasty.
Cardiocentro Ticino n=355
NCT07524335 NOT YET RECRUITING
Aspirin in Subclinical Coronary Artery Disease: A Pilot Randomised Controlled Trial
Montreal Heart Institute n=48
NCT05427084 RECRUITING
Canagliflozin Targeting Vascular Inflammation
Ottawa Heart Institute Research Corporation n=24
NCT07102628 RECRUITING
Evaluation of Efficacy and Safety of Early in Hospital Initiation of Inclisiran Treatment in Patients With Acute Coronary Syndromes
Novartis Pharmaceuticals n=300
NCT05360446 ACTIVE NOT RECRUITING
Coronary Computed Tomography Study to Assess the Effect of Inclisiran in Addition to Maximally Tolerated Statin Therapy on Atherosclerotic Plaque Progression in Participants With a Diagnosis of Non-obstructive Coronary Artery Disease Without Previous Cardiovascular Events
Novartis Pharmaceuticals n=610
NCT06305559 ACTIVE NOT RECRUITING
A CCTA Imaging Trial to Evaluate the Effect of Obicetrapib/Ezetimibe on Coronary Plaque
NewAmsterdam Pharma n=300
NCT07276282 RECRUITING
Effects of Ziltivekimab on Coronary Atherosclerotic Burden in Patients With Acute Myocardial Infarction
ECRI bv n=332
NCT07439133 RECRUITING
Comparison of Diagnostic Accuracy Between XTR004 PET MPI and the Composite Index of Quantitative Coronary Angiography (QCA) and Fractional Flow Reserve (FFR)
Sinotau Pharmaceutical Group n=395
NCT07232069 NOT YET RECRUITING
PRE-EMPT: Prospective RandomizEd Evaluation and Management of Premature aTherosclerosis
Duke University n=1,500
NCT05003817 ACTIVE NOT RECRUITING
Controlled Trial of High-risk Coronary Intervention With Percutaneous Left Ventricular Unloading
Guy's and St Thomas' NHS Foundation Trust n=300
NCT05134012 RECRUITING
RAdiolabeled Perfusion to Identify Coronary Artery Disease Using WAter To Evaluate Responses of Myocardial FLOW (RAPID-WATER-FLOW)
MedTrace Pharma A/S n=215
NCT07357675 NOT YET RECRUITING
A Clinical Trial To Investigate The Effect Of EA-230 On Hospital Length Of Stay In Patients With Coronary Artery Disease (CAD) Undergoing Coronary Artery Bypass Grafting (CABG) Surgery.
EBI Anti Sepsis BV n=300
NCT05918861 RECRUITING
Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS
DalCor Pharmaceuticals n=2,000
NCT07195149 RECRUITING
Comparing High and lOw-dose asPirin With Dual anTIplatelet Therapy for Three Months Using prasUgrel and aSpirin Following Coronary Artery Bypass Grafting. (OPTIMUS-CABG Trial)
Dolnośląskie Centrum Chorób Serca im.prof. Zbigniewa Religi MEDINET Sp. z o.o. n=1,703
NCT06708000 ENROLLING BY INVITATION
Personalized Evaluation of Susptected Myocardial Ischemia
Gødstrup Hospital n=2,000
NCT07268170 ENROLLING BY INVITATION
Heart Rate Control Before Cardiac Computed Tomography in Adults for the Evaluation of Coronary Artery Disease
Gødstrup Hospital n=350
NCT05619653 ACTIVE NOT RECRUITING
Myocardial Protection in Patients With Post-acute Inflammatory Cardiac Involvement Due to COVID-19
Valentina Puentmann n=279
NCT07164859 NOT YET RECRUITING
Safety and Efficacy of Very Short DAPT in Older Patients Undergoing PCI
Vincent ROULE n=1,700
NCT06399705 RECRUITING
REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Minorities
Weill Medical College of Cornell University n=600
NCT06399692 RECRUITING
REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Women
Weill Medical College of Cornell University n=600
NCT05473520 RECRUITING
Doxycycline Host-directed Therapy to Improve Lung Function and Decrease Tissue Destruction in Pulmonary Tuberculosis
National University Hospital, Singapore n=150
NCT06566183 NOT YET RECRUITING
International Study of Comparative Health Effectiveness With Medical and Invasive Approaches-Left Ventricular Dysfunction Trial
NYU Langone Health n=1,200
NCT05549752 RECRUITING
Flecainide Versus Amiodarone in the Cardioversion of Paroxysmal Atrial Fibrillation at the Emergency Department, in Patients With Coronary Artery Disease Without Residual Ischemia
Hippocration General Hospital n=80
NCT01878669 ACTIVE NOT RECRUITING
Effects of N-acetyl Cysteine During Percutaneous Coronary Intervention
Suleyman Demirel University n=390
NCT05952206 ACTIVE NOT RECRUITING
Ischemic and Bleeding Outcomes After Angiolite Stent Implantation and an Abbreviated Dual Antiplatelet Therapy
iVascular S.L.U. n=2,312
NCT05257629 RECRUITING
Aggressive Smoking Cessation Trial (ASAP)
Sir Mortimer B. Davis - Jewish General Hospital n=798
NCT06286878 RECRUITING
Pleiotropic Effects of Dapagliflozin in Patients With Acute Coronary Syndromes
University of Sao Paulo n=80
NCT03789552 RECRUITING
Outcome Research to Confirm the Anti-anginal Effect of T89 in Patients With Stable Angina
Tasly Pharmaceuticals, Inc. n=765
NCT06472908 RECRUITING
Efficacy and Safety of Colchicine After PCI
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology n=8,862
NCT06845254 NOT YET RECRUITING
Clinical Study on the Intervention of Xuesaitong Soft Capsules in Post-Intervention Patients with Acute Coronary Syndrome and Clinical Research Protocol
Xiyuan Hospital of China Academy of Chinese Medical Sciences n=400
NCT06755801 NOT YET RECRUITING
Nebivolol ANOCA Treatment Randomized Trial
Spanish Society of Cardiology n=150
NCT06723002 NOT YET RECRUITING
Effect of Olive Leaf Extracts on Endothelial Dysfunction in Patients With Acute Coronary Syndrome
University of Monastir n=300
NCT06424834 RECRUITING
Efficacy of Targeted Medical Therapy in Angina and Nonobstructive Coronary Arteries
Stanford University n=150
NCT06577519 RECRUITING
Efficacy and Safety Study of Vicagrel in Patients With Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI)
Jiangsu vcare pharmaceutical technology co., LTD n=1,000
NCT06469528 NOT YET RECRUITING
ESCALATion of Medical Therapy Following Multimodality Plaque Evaluation in High-risk Chronic Coronary Syndromes
King's College Hospital NHS Trust n=50
NCT06095765 RECRUITING
Colchicine in Belgium in Patients With Coronary Artery Disease After Percutaneous Coronary Intervention
AZ Sint-Jan AV n=2,770
NCT04777045 ACTIVE NOT RECRUITING
Efficacy of Diltiazem to Improve Coronary Microvascular Dysfunction: a Randomized Clinical Trial
Radboud University Medical Center n=85
NCT03789916 RECRUITING
SAPT Versus DAPT in Incomplete Revascularization After CABG
Campus Bio-Medico University n=800
NCT05175274 NOT YET RECRUITING
Colchicine Use for Primary Prevention of Coronary Artery Disease
Qingdao Central Hospital n=6,792
NCT03313752 COMPLETED
Effects of SGLT2 Inhibition on Myocardial Insulin Sensitivity
Giaccari Andrea n=25
NCT03331484 COMPLETED
The Safety and Efficacy Of Rivaroxaban and Ticagrelor for Patients With Atrial Fibrillation After Percutaneous Coronary Intervention
Ottawa Heart Institute Research Corporation n=40
NCT04093219 COMPLETED
PANDORA: Delirium Prevention After Cardiac Surgery Using IV Acetaminophen to Prevent Postoperative Delirium in Older Cardiac Surgical Patients
Beth Israel Deaconess Medical Center n=900
NCT05754957 COMPLETED
A Study of Milvexian in Participants After a Recent Acute Coronary Syndrome
Janssen Research & Development, LLC n=14,194
NCT02110303 COMPLETED
DIAMOND - Dual Antiplatelet Therapy to Reduce Myocardial Injury
University of Edinburgh n=220
NCT03872401 COMPLETED
Effect of Evolocumab in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke
Amgen n=12,301
NCT01467466 COMPLETED
Prevention of Serious Adverse Events Following Angiography
VA Office of Research and Development n=5,177
NCT04873934 COMPLETED
Management of LDL-cholesterol With Inclisiran + Usual Care Compared to Usual Care Alone in Participants With a Recent Acute Coronary Syndrome
Novartis Pharmaceuticals n=400
NCT04217447 TERMINATED
Assessment of Quitting Versus Using Aspirin Therapy In Patients Treated With Oral Anticoagulation for Atrial Fibrillation or Other Indication With Stabilized Coronary Artery Disease
University Hospital, Brest n=874
NCT04360720 COMPLETED
Percutaneous Coronary Intervention Followed by Antiplatelet Monotherapy in the Setting of Acute Coronary Syndromes
Hospital Israelita Albert Einstein n=3,410
NCT03357874 COMPLETED
TicagRelor Or Clopidogrel in Severe and Terminal Chronic Kidney Disease Patients Undergoing PERcutaneous Coronary Intervention for an Acute Coronary Syndrome.
Assistance Publique Hopitaux De Marseille n=259
NCT03473223 COMPLETED
Study to Investigate CSL112 in Subjects With Acute Coronary Syndrome
CSL Behring n=18,226
NCT00826280 COMPLETED
Caffeine's Effect on Regadenoson Administration With Single Photon Emission Computed Tomography (SPECT) Myocardial Perfusion Imaging (MPI)
Astellas Pharma Inc n=347
NCT01489176 COMPLETED
Regadenoson Real Time Perfusion Imaging Trial-Optison
University of Nebraska n=50
NCT02446990 COMPLETED
Effects of Ivabradine in Patients With Stable Coronary Artery Disease Without Clinical Heart Failure
Institut de Recherches Internationales Servier n=19,102
NCT04560309 COMPLETED
Role of Glutamine as Myocardial Protector in Elective On-Pump CABG Surgery With Low EF
National Cardiovascular Center Harapan Kita Hospital Indonesia n=60
NCT06054100 COMPLETED
The Effect of Colchicine on Inflammation in ACS Patients
Ain Shams University n=88
NCT05998525 COMPLETED
Dapagliflozin Effects on Coronary Calcium and Epicardial Fat Assessed by Cardiotomography
Hilda Elizabeth Macías Cervantes n=54
NCT03354273 COMPLETED
An International Study to Evaluate Diagnostic Efficacy of Flurpiridaz (18F) Injection PET MPI in the Detection of Coronary Artery Disease (CAD)
GE Healthcare n=730
NCT01946815 COMPLETED
Effect of Atorvastatin on Fractional Flow Reserve in Coronary Artery Disease
Keimyung University Dongsan Medical Center n=119
NCT04870073 WITHDRAWN
Retrograde Autologous Priming and Mannitol for Reducing Hemodilution in Cardiac Surgery
Hamilton Health Sciences Corporation
NCT02525939 COMPLETED
Effect of Dalcetrapib vs Placebo on CV Risk in a Genetically Defined Population With a Recent ACS
DalCor Pharmaceuticals n=6,147
NCT04005989 WITHDRAWN
Adipose Stromal Cells Injection in the Myocardium for Induction of Revascularization
Hospital do Coracao
NCT04367935 COMPLETED
Effect of Pentoxifylline on Endothelial Dysfunction in Patients With Acute Coronary Syndrome
Ain Shams University n=43
NCT04001504 COMPLETED
Vaccination Against Influenza to Prevent Cardiovascular Events After Acute Coronary Syndromes
Hospital Israelita Albert Einstein n=1,801
NCT05474053 COMPLETED
Testing P2Y12 Platelet Inhibitors Generics Beyond Bioequivalence
Cairo University n=29
NCT04739384 COMPLETED
Platelet Inhibition With Ticagrelor 60 mg Versus Ticagrelor 90 mg in Elderly Patients With ACS
Federico II University n=50
NCT03570697 COMPLETED
Imaging of Coronary Plaques in Participants Treated With Evolocumab
Amgen n=164
NCT02422446 TERMINATED
Effects of Eicosapentaenoic Acid on Endothelial Function in Diabetic Subjects
Brigham and Women's Hospital n=2
NCT01813435 COMPLETED
GLOBAL LEADERS: A Clinical Study Comparing Two Forms of Anti-platelet Therapy After Stent Implantation
ECRI bv n=15,991
NCT03270514 COMPLETED
Comparison of Sternal Wound Infiltration With Liposomal Bupivacaine v. Bupivacaine Hydrochloride
Kathirvel Subramaniam n=60
NCT00911339 TERMINATED
Mobilization of Endothelial Progenitor Cells Induced by Atorvastatin in Patients With Stable Coronary Artery Disease Treated With Anti-CD 34 Antibodies Coated Stents
Fondazione IRCCS Policlinico San Matteo di Pavia n=13
NCT02586155 COMPLETED
Effect of RVX000222 on Time to Major Adverse Cardiovascular Events in High-Risk T2DM Subjects With CAD
Resverlogix Corp n=2,425
NCT03078465 WITHDRAWN
Ticagrelor Versus High-dose Clopidogrel in Patients With High Platelet Reactivity on Clopidogrel After PCI
Nanjing First Hospital, Nanjing Medical University
NCT02552238 COMPLETED
Evaluation of Safety and Efficacy of Lumason/SonoVue in Subjects Undergoing Pharmacologic Stress BR1-142
Bracco Diagnostics, Inc n=174
NCT02522481 COMPLETED
Evaluation of Safety and Efficacy of Lumason/SonoVue in Subjects Undergoing Pharmacologic Stress BR1-141
Bracco Diagnostics, Inc n=175
NCT03350542 COMPLETED
A Clinical Trial to Assess the SYNERGY 48 mm Stent System for the Treatment of Atherosclerotic Lesion(s)
Boston Scientific Corporation n=100
NCT02017171 COMPLETED
A Multicenter Clinical Trial of Allopurinol to Prevent Kidney Function Loss in Type 1 Diabetes
Alessandro Doria n=530
NCT01347710 COMPLETED
A Phase 3 Multi-center Study to Assess PET Imaging of Flurpiridaz F 18 Injection in Patients With CAD.
Lantheus Medical Imaging n=795
NCT02551094 COMPLETED
Colchicine Cardiovascular Outcomes Trial (COLCOT)
Montreal Heart Institute n=4,745
NCT02617290 COMPLETED
Assessment of Loading With the P2Y12 Inhibitor Ticagrelor or Clopidogrel to Halt Ischemic Events in Patients Undergoing Elective Coronary Stenting
Assistance Publique - Hôpitaux de Paris n=1,900
NCT03369184 TERMINATED
Elective Percutaneous Coronary Intervention With or Without Supplemental OXYgen
Karolinska Institutet n=65
NCT02944123 COMPLETED
Half Dose of Prasugrel and Ticagrelor in Acute Coronary Syndrome (HOPE-TAILOR)
Dong-A University n=120
NCT03482973 COMPLETED
Pecto-Intercostal Fascial Block for Postoperative Analgesia After Cardiac Surgery
Beth Israel Deaconess Medical Center n=80
NCT02236975 COMPLETED
First-in-man Trial Examining the Safety and Efficacy of BuMA Supreme and Resolute Integrity in Patients With de Novo Coronary Artery Stenosis
Sino Medical Sciences Technology Inc. n=168
NCT00950274 TERMINATED
Intramyocardial Transplantation of Bone Marrow Stem Cells in Addition to Coronary Artery Bypass Graft (CABG) Surgery
Miltenyi Biotec B.V. & Co. KG n=81
NCT02237495 COMPLETED
Dexmedetomidine and Outcomes of Cardiac Surgery (DOCS)
Xijing Hospital n=1,100
NCT04361552 WITHDRAWN
Tocilizumab for the Treatment of Cytokine Release Syndrome in Patients With COVID-19 (SARS-CoV-2 Infection)
Emory University
NCT03234348 COMPLETED
MAGnesium-based Bioresorbable Scaffold in ST Segment Elevation Myocardial Infarction
Hospital Clinic of Barcelona n=151
NCT04069234 WITHDRAWN
Study in Diabetes Mellitus Patients Without Prior Myocardial Infarction or Stroke Undergoing Elective Percutaneous Coronary Intervention.
Region Skane
NCT02400632 COMPLETED
MagicTouch Sirolimus Drug Coated Balloon Catheter for the Treatment of Coronary Lesions
Scitech Produtos Medicos SA n=60
NCT02098772 COMPLETED
Phase III Study Comparing Two Methods of Cardioplegia in Aortic Valve Surgery Custodiol-N Versus Custodiol
Dr. F. Köhler Chemie GmbH n=530
NCT00658515 COMPLETED
A Study of RO4607381 in Stable Coronary Heart Disease Patients With Recent Acute Coronary Syndrome
Hoffmann-La Roche n=15,871
NCT03381742 COMPLETED
Efficacy and Safety of Low-dose Ticagrelor
First Affiliated Hospital of Harbin Medical University n=3,043
NCT00965055 TERMINATED
Ezetimibe in Patients Hypo-responsive to Statins
University of California, San Diego n=2
NCT03287609 COMPLETED
EVOlocumab for Early Reduction of LDL-cholesterol Levels in Patients With Acute Coronary Syndromes (EVOPACS)
Insel Gruppe AG, University Hospital Bern n=308
NCT01890434 COMPLETED
Gadobutrol / Gadavist-enhanced Cardiac Magnetic Resonance Imaging (CMRI) to Detect Coronary Artery Disease (CAD)
Bayer n=478
NCT01004406 COMPLETED
Plaque Regression and Progenitor Cell Mobilization With Intensive Lipid Elimination Regimen (PREMIER), Phase I
VA Office of Research and Development n=59
NCT01323153 COMPLETED
A Study of Dalcetrapib in Patients Hospitalized For An Acute Coronary Syndrome (Dal-ACUTE)
Hoffmann-La Roche n=300
NCT00794573 COMPLETED
Evaluation of Varenicline (Champix) in Smoking Cessation for Patients Post-Acute Coronary Syndrome (EVITA) Trial
Mark Eisenberg n=302
NCT01877915 COMPLETED
A Study to Assess the Effectiveness and Safety of Rivaroxaban in Reducing the Risk of Death, Myocardial Infarction or Stroke in Participants With Heart Failure and Coronary Artery Disease Following an Episode of Decompensated Heart Failure
Janssen Research & Development, LLC n=5,081
NCT00624923 COMPLETED
Targeting Inflammation Using Salsalate in CardioVascular Disease
Joslin Diabetes Center n=340
NCT00823212 COMPLETED
The PLATINUM Clinical Trial to Assess the PROMUS Element Stent System for Treatment of De Novo Coronary Artery Lesions
Boston Scientific Corporation n=1,530
NCT01500434 COMPLETED
The PLATINUM Clinical Trial to Assess the PROMUS Element Stent System for Treatment of Long De Novo Coronary Artery Lesions (PLATINUM LL)
Boston Scientific Corporation n=102
NCT01510327 COMPLETED
PLATINUM Trial to Assess the PROMUS Element Stent System for Treatment of De Novo Coronary Artery Lesions-Pharmacokinetics (PLATINUM PK)
Boston Scientific Corporation n=22
NCT01167582 COMPLETED
Myocardial Ischemia and Transfusion Pilot
Rutgers, The State University of New Jersey n=110
NCT01665053 COMPLETED
The EVOLVE II Clinical Trial To Assess the SYNERGY Stent System for the Treatment of Atherosclerotic Lesion(s)
Boston Scientific Corporation n=1,684
NCT02451293 COMPLETED
The Effect of MElatonin on Depression, Anxiety, CIrcadian and Sleep Disturbances in Patients After Acute Myocardial Syndrome
Zealand University Hospital n=252
NCT01508910 COMPLETED
Efficacy and Safety of Targeted Intramyocardial Delivery of Auto CD34+ Stem Cells for Improving Exercise Capacity in Subjects With Refractory Angina
Lisata Therapeutics, Inc. n=291
NCT02044146 COMPLETED
A Pharmacodynamic Study of a Personalized Strategy for P2Y12 Inhibition Versus Ticagrelor in Reducing Ischemic and Bleeding Risk
Ottawa Heart Institute Research Corporation n=120
NCT00934037 COMPLETED
Combined Non-invasive Coronary Angiography and Myocardial Perfusion Imaging Using 320 Detector Computed Tomography
Johns Hopkins University n=444
NCT01755520 TERMINATED
Study Comparing Ticagrelor With Aspirin for Prevention of Vascular Events in Patients Undergoing CABG
Deutsches Herzzentrum Muenchen n=1,893
NCT00616772 COMPLETED
Safety and Efficacy Study Using ABT-335 (Investigational Drug) in Combination With Atorvastatin, to Study the Effects on Thickening of the Blood Vessel Wall in Patients With Abnormal Lipid (Fat) Levels in the Blood
AbbVie (prior sponsor, Abbott) n=682
NCT01890421 COMPLETED
Gadobutrol/Gadavist-enhanced Cardiac Magnetic Resonance Imaging (CMRI) to Detect Coronary Artery Disease (CAD)
Bayer n=426
NCT03122340 COMPLETED
Polyprenols (Ropren) in Acute Coronary Syndrome
Tomsk National Research Medical Center of the Russian Academy of Sciences n=70
NCT02339454 COMPLETED
Efficacy of Extracorporeal Shockwave Myocardial Revascularization Therapy in Patients With Stable Angina Pectoris
Evgeny Shkolnik, MD n=72
NCT00781118 COMPLETED
AngelMed for Early Recognition and Treatment of STEMI
Angel Medical Systems n=1,020
NCT02482857 COMPLETED
Optimal Dose of Acetylsalicylic Acid After Coronary Artery Bypass Grafting
Karolinska University Hospital n=45
NCT01453582 COMPLETED
Efficacy and Safety Study of Total Flavonoids of Propolis Dropping Pill to Treat Angina Pectoris
Shanghai Greenvalley Pharmaceutical Co., Ltd. n=478
NCT01217307 COMPLETED
Metformin to Reduce Heart Failure After Myocardial Infarction
University Medical Center Groningen n=380
NCT01797484 COMPLETED
Reduction of Ischemic Myocardium With Ranolazine-Treatment in Patients With Acute Myocardial Ischemia
Universitätsklinikum Hamburg-Eppendorf n=20
NCT02290080 COMPLETED
Determination of the Role of Oxygen in Suspected Acute Myocardial Infarction by Biomarkers
Karolinska Institutet n=175
NCT01787110 COMPLETED
An Efficacy and Outcome Study of Supplemental Oxygen Treatment in Patients With Suspected Myocardial Infarction
Karolinska Institutet n=6,629
NCT00685776 COMPLETED
Study to Assess the Tolerability and Efficacy of Anacetrapib in Patients With Coronary Heart Disease (CHD) or CHD Risk-Equivalent Disease (MK-0859-019)
Merck Sharp & Dohme LLC n=1,623
NCT02266030 COMPLETED
Effect of Cilostazol on Coronary Artery Stenosis and Plaque Characteristics in Patients With T2DM
Seoul National University Bundang Hospital n=100
NCT02920125 COMPLETED
Study the Result of Ayurvedic SUVED & Reimmugen (Colostrum) Treatment on Vascular Disease, CAD, CVA, DVT.
Sujata Vaidya n=96
NCT01260207 TERMINATED
Using IVR to Maintain ACS Patients on Best Practice Guidelines
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's n=654
NCT01000727 COMPLETED
The Stabilization Of pLaques usIng Darapladib-Thrombolysis In Myocardial Infarction 52 Trial
GlaxoSmithKline n=13,026
NCT01754259 COMPLETED
Effects of Ranolazine on Coronary Flow Reserve in Symptomatic Diabetic Patients and CAD
Brigham and Women's Hospital n=47
NCT02145468 COMPLETED
A Phase 3 Clinical Outcomes Study to Compare the Incidence of Major Adverse Cardiovascular Events in Subjects Presenting With Acute Coronary Syndrome Treated With Losmapimod Compared to Placebo (LATITUDE-TIMI 60)
GlaxoSmithKline n=3,503
NCT02087007 COMPLETED
A Therapeutic Confirmatory Study to Evaluate the Efficacy and Safety of Cilostazol in Subjects With Vasospastic Angina
Korea Otsuka Pharmaceutical Co., Ltd. n=100
NCT00965406 COMPLETED
Glucose Insulin Potassium With Intensive Insulin Therapy and (GIK2) Versus GIK Alone
University of Monastir n=772
NCT00981383 COMPLETED
Treating Depression in Coronary Artery Disease With Omega-3 Fatty Acids
Sunnybrook Health Sciences Centre n=92
NCT02294942 COMPLETED
Extended-Release RANCAD in the Patients With Stable Angina Pectoris
TSH Biopharm Corporation Limited n=75
NCT01894789 COMPLETED
Ticagrelor vs Clopidogrel Effect on MFR in CAD Population
Ottawa Heart Institute Research Corporation n=36
NCT01659580 COMPLETED
Phase III Trial of Dantonic® (T89) Capsule to Prevent and Treat Stable Angina
Tasly Pharmaceuticals, Inc. n=1,004
NCT02350439 COMPLETED
Differential Effect of High (200μg/kg/Min) Adenosine Dose on Fractional Flow Reserve in Patients Presenting Variation of FFR ≥0.05 During the Usual Dose of Adenosine Infusion (140μg/kg/Min).
University of Patras n=30
NCT01147250 COMPLETED
Evaluation of Cardiovascular Outcomes in Patients With Type 2 Diabetes After Acute Coronary Syndrome During Treatment With AVE0010 (Lixisenatide)
Sanofi n=6,068
NCT01516541 COMPLETED
A Study of Dalcetrapib in Patients With Stable Coronary Heart Disease, With Coronary Heart Disease Risk Equivalents or at Elevated Risk for Cardiovascular Disease
Hoffmann-La Roche n=2,220
NCT02269722 COMPLETED
Postcath Radial Arterial Clamp Time In the CAth Lab
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's n=564
NCT01805596 COMPLETED
Effect of Ticagrelor on Endothelial Function
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's n=45
NCT01550614 TERMINATED
Efficacy and Safety of Ad5FGF-4 for Myocardial Ischemia in Patients With Stable Angina Due to Coronary Artery Disease
Cardium Therapeutics n=11
NCT00706849 COMPLETED
Efficacy and Safety Study of ISIS 301012 (Mipomersen) as Add-on in Familial Hypercholesterolemic Patients With Coronary Artery Disease
Kastle Therapeutics, LLC n=124
NCT00770146 COMPLETED
Safety and Efficacy of Mipomersen (ISIS 301012) As Add-on Therapy in High Risk Hypercholesterolemic Patients
Kastle Therapeutics, LLC n=158
NCT00794664 COMPLETED
Safety and Efficacy of Mipomersen in Patients With Severe Hypercholesterolemia on a Maximally Tolerated Lipid-Lowering Regimen and Who Are Not on Apheresis
Kastle Therapeutics, LLC n=58
NCT02291484 COMPLETED
Comprehensive Cardiac CT Versus Exercise Testing in Suspected Coronary Artery Disease (2)
Erasmus Medical Center n=250
NCT01442038 COMPLETED
Ranolazine for Incomplete Vessel Revascularization Post-Percutaneous Coronary Intervention (PCI)
Gilead Sciences n=2,651
NCT01873222 COMPLETED
OPtical Frequency Domain Imaging Versus INtravascular Ultrasound in Percutaneous Coronary InterventiON - OPINION Imaging
Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan n=106
NCT01873027 COMPLETED
OPtical Frequency Domain Imaging vs. INtravascular Ultrasound in Percutaneous Coronary InterventiON
Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan n=829
NCT01076764 COMPLETED
Effect of Otamixaban Versus Unfractionated Heparin + Eptifibatide in Patients With Unstable Angina/Non ST Elevation Myocardial Infarction Undergoing Early Invasive Strategy
Sanofi n=13,220
NCT02452736 COMPLETED
Acute Safety, Deliverability and Efficacy of the Medtronic Resolute Integrity™ Zotarolimus-Eluting Coronary Stent System in the Treatment of Suitable Patients According to Indication for Use (CHINA RESOLUTE INTEGRITY STUDY)
Medtronic Vascular n=205
NCT00516178 COMPLETED
Intravenous Fish Oil in Critically Ill Cardiac Patients
Centre Hospitalier Universitaire Vaudois n=31
NCT01087723 COMPLETED
European Ambulance Acute Coronary Syndrome (ACS) Angiography Trial
The Medicines Company n=2,198
NCT01618669 COMPLETED
A Study to Assess Regadenoson Administration Following an Inadequate Exercise Stress Test as Compared to Regadenoson Alone for Myocardial Perfusion Imaging (MPI) Using Single Photon Emission Computed Tomography (SPECT)
Astellas Pharma Global Development, Inc. n=1,147
NCT01373216 COMPLETED
Glucagon-like Peptide 1 Agonist Exenatide for Improved Glucose Control and Cardiac Function in Patients With Aortocoronary Bypass
Charles University, Czech Republic n=38
NCT02094469 COMPLETED
Safety and Efficacy Study of Cilostazol to Treat Vasospastic Angina
Korea Otsuka Pharmaceutical Co., Ltd. n=65
NCT01294163 COMPLETED
Xenon Compared to Sevoflurane and Total Intravenous Anaesthesia for Coronary Artery Bypass Graft Surgery
Air Liquide Santé International n=509
NCT01146080 COMPLETED
Optical Coherence Tomography for EVERolimus Eluting STent
A.O. Ospedale Papa Giovanni XXIII n=42
NCT01373645 COMPLETED
Safety and Efficacy Registry of Yinyi Stent
Shanghai Jiao Tong University School of Medicine n=1,045
NCT01093391 COMPLETED
A Trial of Bare Metal Stent - Cobalt Chromium Versus Stent Coating With Sirolimus
Scitech Produtos Medicos SA n=63
NCT00910065 COMPLETED
BAY81-8781, I.V. Aspirin in the Indication of Acute Coronary Syndrome (ACS)
Bayer n=270
NCT01356992 TERMINATED
Patients With High-risk Acute Coronary Syndrome Without ST-segment Elevation
Eurofarma Laboratorios S.A. n=62
NCT02070679 COMPLETED
Efficacy of Vitamin E in Preventing Contrast-Induced Acute Kidney Injury Following Coronary Angiography
Urmia University of Medical Sciences n=284
NCT01774838 COMPLETED
Vasoactive and Anti-inflammatory Effects of Prasugrel in Acute Coronary Syndrome
University of Cologne n=49
NCT01247545 COMPLETED
Effect of Remote Ischaemic Preconditioning on Clinical Outcomes in CABG Surgery
University College, London n=1,612
NCT01183442 TERMINATED
Vitamin D Supplementation in CAD and Postchallenge Hyperglycemia
Medical University of Graz n=22
NCT01368770 COMPLETED
Stress Testing Compared to Coronary Computed Tomographic Angiography in Patients With Suspected Coronary Artery Disease
All India Institute of Medical Sciences n=303
NCT01992523 COMPLETED
Mojito Study (Mashed Or Just Integral Pill of TicagrelOr ? )
David Antoniucci n=82
NCT01608100 COMPLETED
Evaluation of a New Cardiac Biomarker Assay
Abbott Diagnostics Division n=1,101
NCT01669382 COMPLETED
Angio-Seal® vs. Exo-Seal® for Closure of Arterial Puncture Sites
University Hospital Erlangen n=304
NCT01798277 WITHDRAWN
Trial Comparing Ablation With Medical Therapy in Patients With Ventricular Tachycardia
Newmarket Electrophysiology Research Group Inc
NCT01609647 COMPLETED
Reloading Prasugrel or Clopidogrel on High Platelet Reactivity Before Percutaneous Coronary Intervention
Dong-A University n=76
NCT02294643 COMPLETED
Study Design of 'Influence of Sarpogrelate in Patients With Renal Impairment or Diabetes Mellitus' Study
Seoul National University Bundang Hospital n=220
NCT01848106 TERMINATED
A Study To Determine the Efficacy and Safety of REG1 Compared to Bivalirudin in Patients Undergoing PCI
Regado Biosciences, Inc. n=3,232
NCT00809965 COMPLETED
An Efficacy and Safety Study for Rivaroxaban in Patients With Acute Coronary Syndrome
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. n=15,526
NCT01626534 COMPLETED
Evaluation of Ticagrelor Anti Platelet and Pleiotropic Effects in Patients Undergoing Percutaneous Coronary Intervention for an Acute Coronary Syndrome
Assistance Publique Hopitaux De Marseille n=125
NCT00939237 COMPLETED
Trial of Lycopene/Ateronon for Secondary Prevention of Coronary Heart Disease
Brigham and Women's Hospital n=213
NCT00944333 TERMINATED
Second Generation" Drug-Eluting Stents Implantation Followed by Six Versus Twelve-Month - Dual Antiplatelet Therapy
Fondazione Evidence per Attività e Ricerche Cardiovascolari ONLUS n=1,378
NCT02205775 TERMINATED
Rosuvastatin for Reduction of Myocardial Damage and Systemic Inflammation During Coronary Angioplasty
G. d'Annunzio University n=280
NCT01294462 COMPLETED
Study to Assess Safety and Efficacy of Ticagrelor (AZD6140) Versus Clopidogrel in Asian/Japanese Patients With Non-ST or ST Elevation Acute Coronary Syndromes (ACS)
AstraZeneca n=801
NCT00732953 COMPLETED
Prevention of Restenosis After Genous Stent Implantation Using a Paclitaxel Eluting Balloon in Coronary Arteries
University of Ulm n=120
NCT00853827 COMPLETED
Safety and Efficacy of Aliskiren on the Progression of Atherosclerosis in Coronary Artery Disease Patients
Novartis Pharmaceuticals n=613
NCT01012414 TERMINATED
Effect of Vitamin D Supplement on Inflammation Markers in High-Risk Cardiovascular Patients With Chronic Kidney Disease
Thomas Jefferson University n=10
NCT01379677 COMPLETED
Rubidium-82 PET and Tc-99m-MIBI SPET: A Head to Head Comparison
Advanced Accelerator Applications n=135
NCT01084239 COMPLETED
Multicenter Study to Rule Out Myocardial Infarction by Cardiac Computed Tomography
Massachusetts General Hospital n=1,000
NCT00968708 COMPLETED
Cardiovascular Outcomes Study of Alogliptin in Patients With Type 2 Diabetes and Acute Coronary Syndrome
Takeda n=5,380
NCT01819701 COMPLETED
L-carnitine and Coenzyme Q10 in Relation to the Oxidative Stress, Antioxidant Enzymes Activities, Inflammation, and the Risk of Coronary Artery Disease
Taichung Veterans General Hospital n=47
NCT01156571 COMPLETED
A Clinical Trial Comparing Cangrelor to Clopidogrel Standard Therapy in Subjects Who Require Percutaneous Coronary Intervention (PCI) (CHAMPION PHOENIX)
The Medicines Company n=11,145
NCT01031095 COMPLETED
(A Novel Pharmacologic Regime for Elective Percutaneous Coronary Intervention)
Bursa Postgraduate Hospital n=200
NCT01543932 COMPLETED
High Clopidogrel Dose Versus Prasugrel and Ticagrelor in High Reactive Stable Patients
University of Roma La Sapienza n=81
NCT01035567 COMPLETED
Safety and Efficacy Study of Hybrid Revascularization in Multivessel Coronary Artery Disease
Silesian Centre for Heart Diseases n=200
NCT01635881 COMPLETED
Evaluation of Coronary Luminal Diameter Enlargement With Emerge™ 1.20 mm PTCA Dilatation Catheter
Boston Scientific Corporation n=60
NCT01478126 COMPLETED
Effects of Glutamine in Ischemic Heart Disease Patients Following Cardiopulmonary Bypass
Meshalkin Research Institute of Pathology of Circulation n=24
NCT01163500 COMPLETED
Coenzyme Q10 in Relation of the Lipid Peroxidation, Antioxidant Enzyme Activities in Coronary Artery Disease Patients
Taichung Veterans General Hospital n=59
NCT01519245 COMPLETED
Topical Application of Tranexamic Acid to Reduce Post-operative Bleeding in Coronary Artery Bypass Surgery
University of Saskatchewan n=44
NCT01424761 COMPLETED
Coenzyme Q10 in Relation to the Antioxidative Vitamins, Oxidative Stress and Inflammation in Coronary Artery Disease Patients During Statin Therapy
Taichung Veterans General Hospital n=51
NCT01681524 WITHDRAWN
Open Label Study to Access Flurpiridaz F18 in PET MPI Verses SPECT MPI
Lantheus Medical Imaging
NCT01757262 WITHDRAWN
A Clinical Study of Safety and P2Y12 Receptor Inhibition Effects of Ticagrelor and Clopidogrel in Vietnamese Patient
AstraZeneca
NCT00699998 COMPLETED
A Comparison of Prasugrel and Clopidogrel in Acute Coronary Syndrome Subjects
Eli Lilly and Company n=9,326
NCT00822666 COMPLETED
Clopidogrel and Response Variability Investigation Study 2
Assistance Publique - Hôpitaux de Paris n=109
NCT01130246 TERMINATED
VISTA-16 Trial: Evaluation of Safety and Efficacy of Short-term A-002 Treatment in Subjects With Acute Coronary Syndrome
Anthera Pharmaceuticals n=5,189
NCT01202058 TERMINATED
An Observational Safety Evaluation of Patients Treated With the NEVO™ Sirolimus-eluting Coronary Stent. (NEVO II)
Cordis US Corp. n=156
NCT00824434 COMPLETED
A Prospective, Multi-center Trial to Assess an Everolimus-Eluting Coronary Stent System (PROMUS Element™)
Boston Scientific Corporation n=100
NCT01360437 COMPLETED
Ticagrelor Versus Prasugrel in Acute Coronary Syndromes After Percutaneous Coronary Intervention
University of Patras n=44
NCT00793221 COMPLETED
Non-acute Coronary occlusIon Treated By Everolimus ELuting Stent
Raul Moreno n=207
NCT00924586 COMPLETED
Study of ONO-1101 in Patients Scheduled for Multi-Slice Computed Tomography (CT)
Ono Pharmaceutical Co., Ltd. n=258
NCT01231165 COMPLETED
Treatment of Coronary Heart Disease With Amiloride
University of Carabobo n=70
NCT01239654 COMPLETED
Activity of Platelets After Inhibition and Cardiovascular Events Optical Coherence Tomography Study
IRCCS San Raffaele n=60
NCT01313572 TERMINATED
Study of the Safety and Efficacy of Apadenoson for Detection of Myocardial Perfusion Defects Using SPECT MPI
Forest Laboratories n=197
NCT00990327 TERMINATED
Study of the Safety and Efficacy of Apadenoson for Detection of Myocardial Perfusion Defects Using SPECT MPI
Forest Laboratories n=863
NCT01578876 COMPLETED
Extracorporeal Cardiac Shock Wave Therapy (CSWT) for Treatment of Coronary Artery Disease
Kunming Medical University n=55
NCT01465828 COMPLETED
Therapy With High Clopidogrel Dose or Prasugrel Standard Dose Reduces the Platelet Reactivity in Patients With Genotype Variation RESET GENE Trial
Gennaro Sardella n=30
NCT01184300 COMPLETED
ReAssessment of Anti-Platelet Therapy Using an InDividualized Strategy Based on GENetic Evaluation
Ottawa Heart Institute Research Corporation n=200
NCT00830960 COMPLETED
A Comparison of Antiplatelet Therapies in Asian Subjects With Acute Coronary Syndrome
Eli Lilly and Company n=720
NCT01304472 COMPLETED
Prasugrel Versus High Dose Clopidogrel in Patients With Stable Coronary Artery Disease and High Platelet Reactivity While on Chronic Clopidogrel Treatment
University of Patras n=25
NCT00821834 COMPLETED
Safety Evaluation of Clopidogrel Sulfate in Patients With Stable Angina/Old Myocardial Infarction to Whom Percutaneous Coronary Intervention is Being Planned
Sanofi n=1,003
NCT00639158 COMPLETED
Safety and Efficacy Study Comparing ABT-335 Coadministered With Atorvastatin and Ezetimibe to Atorvastatin Coadministered With Ezetimibe in Subjects With Multiple Abnormal Lipid (Fat) Levels in the Blood
Abbott n=543
NCT01272986 COMPLETED
Trial of Screening for ALOA-IgG AtheroAbzyme Test
Omicron Pharmaceuticals n=100
NCT01109784 COMPLETED
Prasugrel Versus High Dose Clopidogrel in Clopidogrel Resistant Patients Post Percutaneous Coronary Intervention (PCI).
University of Patras n=70
NCT00722579 COMPLETED
A Study of the Presillion Stent in de Novo Coronary Lesions
Cordis US Corp. n=101
NCT00638326 TERMINATED
Doubling the Maintenance Dose of Clopidogrel in Patients With High On-Clopidogrel Platelet Reactivity
University of Pecs n=500
NCT01032668 COMPLETED
The EFFect of hIgh Dose ClopIdogrel treatmENT in Patients With Clopidogrel Resistance
Bursa Postgraduate Hospital n=192
NCT00754819 COMPLETED
Targeting Inflammation in Acute Coronary Syndrome Using Colchicine
Hamilton Health Sciences Corporation n=80
NCT00607178 COMPLETED
The Efficacy of Influenza Vaccine in Reducing Cardiovascular Events in Patients With Coronary Artery Diseases
Shahid Beheshti University of Medical Sciences n=300
NCT00607217 COMPLETED
The Efficacy of Influenza Vaccination in Patients With Coronary Artery Diseases
Shahid Beheshti University of Medical Sciences n=360
Data: ClinicalTrials.gov · Trials registered 2008 onwards · Industry sponsors only