Fungal Infections Clinical Trial Landscape
Data updated: May 20, 2026
220 clinical trials tracked since 2008
Fungal Infections is being studied across 220 clinical trials registered since 2008, with 31 programs currently active. The competitive pipeline includes 12 active Phase 3 trials, 15 active Phase 2 trials, and 5 active Phase 1 trials. Top industry sponsors include Merck, F2G Biotech GmbH, Basilea Pharmaceutica.
31 active
/
220 total (since 2008)
5
Phase 1 Active
58 total
15
Phase 2 Active
73 total
12
Phase 3 Active
68 total
5
Phase 4 Active
39 total
Top Industry Sponsors
Sorted by active Active Done Failed
Merck 1 12 4
F2G Biotech GmbH 1 10 4
Basilea Pharmaceutica 1 5 1
Mundipharma Research Limited 1 1 1
Sano Chemicals Inc 1 0 0
+ 10 more sponsors — see full table below
Featured Phase 3 Trials
NCT05421858 RECRUITING
A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Participants With Candidemia and/or Invasive Candidiasis.
Basilea Pharmaceutica n=450
NCT07109869 RECRUITING
Safety and Efficacy of Boric Acid Inserts for Treatment of Vulvovaginal Candidiasis
pH-D Feminine Health LLC n=400
NCT04227483 ACTIVE NOT RECRUITING
Deflazacort Vs. Prednisolone in Acute-stage ABPA
Post Graduate Institute of Medical Education and Research, Chandigarh n=150
NCT06174922 RECRUITING
A Randomized Trial of Prednisolone, Itraconazole, or Their Combination in Allergic Bronchopulmonary Aspergillosis
Post Graduate Institute of Medical Education and Research, Chandigarh n=300
+ 63 more Phase 3 trials — see full database below
Fungal Infections — Trials Started by Year (last 10 years)
2016 14
2017 11
2018 16
2019 19
2020 10
2021 7
2022 9
2023 6
2024 10
2025 8
2026 5
TheraRadar.com
Full Trial Database
Complete sponsor table, every trial across all phases, plus competitive analytics. Sortable, filterable, exportable for Pro users.
Top Sponsors (all-time)
Merck 17
F2G Biotech GmbH 15
Basilea Pharmaceutica 7
Mundipharma Research Limited 3
Sano Chemicals Inc 1
pH-D Feminine Health LLC 1
LimmaTech Biologics AG 1
Biosergen AS 1
AVVA Pharmaceuticals Ltd. 1
Fujian Shengdi Pharmaceutical Co., Ltd. 1
Active Trials by Phase
Phase 1 5
Phase 2 15
Phase 3 12
Phase 4 5
Enrollment Size Distribution
1-50 103
51-200 66
201-500 34
501-1k 5
1k+ 1
All Industry Sponsors
Sorted by active Active Done Failed
Merck 1 12 4
F2G Biotech GmbH 1 10 4
Basilea Pharmaceutica 1 5 1
Mundipharma Research Limited 1 1 1
Sano Chemicals Inc 1 0 0
pH-D Feminine Health LLC 1 0 0
LimmaTech Biologics AG 1 0 0
Biosergen AS 1 0 0
AVVA Pharmaceuticals Ltd. 1 0 0
Fujian Shengdi Pharmaceutical Co., Ltd. 1 0 0
NEXBIOME THERAPEUTICS 1 0 0
Pfizer 0 7 6
Scynexis, Inc. 0 8 2
Pulmocide Ltd 0 2 3
Mycovia Pharmaceuticals Inc. 0 3 0
NCT05421858 RECRUITING
A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Participants With Candidemia and/or Invasive Candidiasis.
Basilea Pharmaceutica n=450
NCT07109869 RECRUITING
Safety and Efficacy of Boric Acid Inserts for Treatment of Vulvovaginal Candidiasis
pH-D Feminine Health LLC n=400
NCT06774144 ENROLLING BY INVITATION
Rezafungin Prophylaxis in Liver Transplant
Fernanda P Silveira, MD, MS n=385
NCT04227483 ACTIVE NOT RECRUITING
Deflazacort Vs. Prednisolone in Acute-stage ABPA
Post Graduate Institute of Medical Education and Research, Chandigarh n=150
NCT06174922 RECRUITING
A Randomized Trial of Prednisolone, Itraconazole, or Their Combination in Allergic Bronchopulmonary Aspergillosis
Post Graduate Institute of Medical Education and Research, Chandigarh n=300
NCT03656081 RECRUITING
Chronic Pulmonary Aspergillosis and Ambisome Aerosol with Itraconazole
Poitiers University Hospital n=224
NCT06835361 RECRUITING
Efficacy and Safety of Clotrimazole+Lactulose Vaginal Suppositories Vs. Clotrimazole Monotherapy in Adult Women with Candidal Vaginitis/Vulvovaginitis
AVVA Pharmaceuticals Ltd. n=264
NCT05814432 RECRUITING
Efficacy and Safety of High-dose Liposomal Amphotericin B for Disseminated Histoplasmosis in AIDS
Federal University of Health Science of Porto Alegre n=279
NCT06447402 RECRUITING
A Trial to Compare Nebulized Amphotericin B and Nebulized Normal Saline as Maintenance in Patients With Chronic Pulmonary Aspergillosis
Post Graduate Institute of Medical Education and Research, Chandigarh n=196
NCT05367089 RECRUITING
The Effect of Medical Grade Honey Formulation (L-Mesitran) Administration on Recurrent Vulvovaginal Candidiasis Symptoms
Maastricht University Medical Center n=252
NCT04368559 COMPLETED
Study of Rezafungin Compared to Standard Antimicrobial Regimen for Prevention of Invasive Fungal Diseases in Adults Undergoing Allogeneic Blood and Marrow Transplantation
Mundipharma Research Limited n=602
NCT03562156 COMPLETED
A Study of Oral Oteseconazole for the Treatment of Patients With Recurrent Vaginal Candidiasis (Yeast Infection)
Mycovia Pharmaceuticals Inc. n=438
NCT03561701 COMPLETED
A Study of Oral Oteseconazole (VT-1161) for the Treatment of Patients With Recurrent Vaginal Candidiasis (Yeast Infection)
Mycovia Pharmaceuticals Inc. n=425
NCT05178862 TERMINATED
A Phase 3, Randomized, Double-blind Study for Patients With Invasive Candidiasis Treated With IV Echinocandin Followed by Either Oral Ibrexafungerp or Oral Fluconazole
Scynexis, Inc. n=68
NCT02145832 COMPLETED
Fluconazole Versus Micafungin in Neonates With Candidiasis
Institut National de la Santé Et de la Recherche Médicale, France n=100
NCT05707832 COMPLETED
A Study of ABCD for Injection in Subjects With Invasive Candidiasis and Invasive Aspergillus
CSPC Ouyi Pharmaceutical Co., Ltd. n=31
NCT00634049 COMPLETED
Isavuconazole in the Treatment of Renally Impaired Aspergillosis and Rare Fungi
Astellas Pharma Inc n=149
NCT03059992 COMPLETED
Study to Evaluate the Efficacy and Safety of Ibrexafungerp in Patients With Fungal Diseases That Are Refractory to or Intolerant of Standard Antifungal Treatment
Scynexis, Inc. n=233
NCT01503515 COMPLETED
Caspofungin Acetate, Fluconazole, or Voriconazole in Preventing Fungal Infections in Patients Following Donor Stem Cell Transplant
Children's Oncology Group n=292
NCT04824417 COMPLETED
A Randomized Controlled Trial to Compare the Clinical Outcomes With Six Months of Therapy With Oral Itraconazole Versus Oral Voriconazole for Management of Treatment naïve Subjects With Chronic Pulmonary Aspergillosis
Post Graduate Institute of Medical Education and Research, Chandigarh n=116
NCT05399641 COMPLETED
Ibrexafungerp for the Treatment of Complicated Vulvovaginal Candidiasis
Scynexis, Inc. n=150
NCT03363841 COMPLETED
Open-Label Study to Evaluate the Efficacy and Safety of Oral Ibrexafungerp (SCY-078) in Patients With Candidiasis Caused by Candida Auris (CARES)
Scynexis, Inc. n=30
NCT06411314 COMPLETED
Efficacy and Safety of Natamycin and Lactulose Vaginal Suppositories in Treatment of Vulvovaginal Candidiasis
Avva Rus, JSC n=218
NCT04876716 TERMINATED
Azole-echinocandin Combination Therapy for Invasive Aspergillosis
Erasmus Medical Center n=66
NCT01782131 COMPLETED
A Study of the Safety and Efficacy of Posaconazole Versus Voriconazole for the Treatment of Invasive Aspergillosis (MK-5592-069)
Merck Sharp & Dohme LLC n=585
NCT01288378 COMPLETED
Empirical Versus Preemptive Antifungal Therapy
European Organisation for Research and Treatment of Cancer - EORTC n=556
NCT03572049 COMPLETED
Endemic Mycoses Treatment With SUBA-itraconazole vs Itraconazole
University of Alabama at Birmingham n=88
NCT04029116 COMPLETED
Phase 3 Study of Oral Ibrexafungerp (SCY-078) Vs. Placebo in Subjects With Recurrent Vulvovaginal Candidiasis (VVC)
Scynexis, Inc. n=440
NCT03667690 COMPLETED
Study of Rezafungin Compared to Caspofungin in Subjects With Candidemia and/or Invasive Candidiasis
Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) n=199
NCT04707703 TERMINATED
Isavuconazole for the Prevention of COVID-19-associated Pulmonary Aspergillosis
Jeffrey Jenks, MD, MPH n=8
NCT02440009 COMPLETED
A Randomized Trial of Itraconazole in Acute Stages of Allergic Bronchopulmonary Aspergillosis
Post Graduate Institute of Medical Education and Research, Chandigarh n=191
NCT03840616 COMPLETED
Study of Oral Oteseconazole (VT-1161) for Acute Yeast Infections in Patients With Recurrent Yeast Infections
Mycovia Pharmaceuticals Inc. n=219
NCT02879305 COMPLETED
Anemia Studies in Chronic Kidney Disease: Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor Daprodustat-Dialysis (ASCEND-D)
GlaxoSmithKline n=2,964
NCT03920527 COMPLETED
Six Months Versus 12 Months of Oral Itraconazole Therapy for Management of Treatment naïve Subjects With CPA
Post Graduate Institute of Medical Education and Research, Chandigarh n=164
NCT01307579 COMPLETED
Caspofungin Versus Fluconazole in Preventing Invasive Fungal Infections (IFI) in Patients Undergoing Chemotherapy for Acute Myeloid Leukemia
Children's Oncology Group n=517
NCT02180165 COMPLETED
Assessing the Safety and Efficacy of MK-5592 (Posaconazole) in Japanese Participants With Fungal Infection (MK-5592-101)
Merck Sharp & Dohme LLC n=116
NCT01371656 COMPLETED
Levofloxacin in Preventing Infection in Young Patients With Acute Leukemia Receiving Chemotherapy or Undergoing Stem Cell Transplantation
Children's Oncology Group n=624
NCT02907307 WITHDRAWN
Efficacy, Safety LactiSal 1% Gel, LactSal 50 mg, Clotrimazole 100 mg Tablet in Treatment Vulvovaginal Candidiasis
Medinova AG
NCT00734539 COMPLETED
Fluconazole Prophylaxis for the Prevention of Candidiasis in Infants Less Than 750 Grams Birthweight
Daniel Benjamin n=362
NCT01621321 COMPLETED
Voriconazole Versus Oral Steroids in Allergic Bronchopulmonary Aspergillosis
Post Graduate Institute of Medical Education and Research, Chandigarh n=50
NCT00836875 TERMINATED
A Study To Evaluate The Safety Of Voriconazole As Treatment Of Invasive Aspergillosis (Fungal Infection) And Other Rare Molds In Children
Pfizer n=31
NCT00811642 COMPLETED
Posaconazole Treatment of Invasive Fungal Infection (IFI) (P05551)
Merck Sharp & Dohme LLC n=63
NCT00635648 COMPLETED
A Study of Caspofungin Acetate (MK0991) for the Treatment of Esophageal Candidiasis or Invasive Candidiasis in Chinese Adults (MK-0991-066)
Merck Sharp & Dohme LLC n=63
NCT00717860 COMPLETED
A Clinical Study of MK0991 (Caspofungin) in Japanese Patients With Deep-seated Candida or Aspergillus Infections (0991-062)(COMPLETED)
Merck Sharp & Dohme LLC n=121
NCT01321827 COMPLETED
Monotherapy of Itraconazole Versus Prednisolone in Allergic Bronchopulmonary Aspergillosis
Post Graduate Institute of Medical Education and Research, Chandigarh n=100
NCT00750737 COMPLETED
Oral Posaconazole Three Times Per Day vs Weekly High Dose Amphotericin B Lipid Complex (ABLC)
M.D. Anderson Cancer Center n=46
NCT02818803 COMPLETED
Efficacy of Standardized-propolis Extract (EPP-AF®) Gel Formulation as Buccal Antiseptic
University of Sao Paulo n=40
NCT01092832 TERMINATED
A Study Of The Safety, Tolerability And Effective Of Voriconazole For The Treatment Of Serious Candida Infection And Candida Infection Of The Throat In Pediatric Patients
Pfizer n=23
NCT00794703 COMPLETED
A Study to Compare Efficacy and Safety of Mycamine® and Itraconazole for Preventing Fungal Infections
Astellas Pharma Inc n=288
NCT02251093 COMPLETED
Study of the Efficacy and Tolerance of Intra-vaginal Treatment With a Total Freeze-dried Culture of Lcr Regenerans® in the Prevention of Relapses of Recurrent Vulvovaginal Candidiasis
Probionov n=350
NCT00815516 TERMINATED
Study to Compare the Efficacy and Safety of Micafungin Versus Conventional Amphotericin B for the Treatment of Neonatal Candidiasis
Astellas Pharma Global Development, Inc. n=30
NCT01293643 COMPLETED
A Study to Compare the Efficacy and Safety of a Combination of Ketoconazole and Clindamycin Compared to Tetracycline/Amphotericin B Combination Cream for the Treatment of Bacterial Vaginosis and Vaginal Candidiasis (P08077)
Merck Sharp & Dohme LLC n=99
NCT01857479 COMPLETED
A Randomized Controlled Trial of Inhaled Amphotericin B for Maintaining Remission in Allergic Bronchopulmonary Aspergillosis
Post Graduate Institute of Medical Education and Research, Chandigarh n=21
NCT00974766 COMPLETED
Trial on the Efficacy and Safety of Two Different Glucocorticoid Dose Regimens in Allergic Bronchopulmonary Aspergillosis
Post Graduate Institute of Medical Education and Research, Chandigarh n=92
NCT00805740 TERMINATED
An Evaluation Of The Effectiveness And Safety Of Anidulafungin Compared To Caspofungin For The Treatment Of Deep Tissue Infection Due To Candida
Pfizer n=41
NCT00784368 COMPLETED
A Pharmacokinetic Study of JK1211(Itraconazole [Itrizole]) Oral Solution in Participants With Deep Mycosis and Those With Febrile Neutropenia Suspected of Fungal Infection
Janssen Pharmaceutical K.K. n=55
NCT00806351 TERMINATED
An Evaluation Of The Effectiveness And Safety Of Anidulafungin Compared To Caspofungin For The Treatment Of Serious Fungal Infection Due To Candida In Patients With A Dysfunctional Immune System
Pfizer n=21
NCT00904995 COMPLETED
Beta Glucan Assay in Patients Receiving Voriconazole Prophylaxis
M.D. Anderson Cancer Center n=23
NCT01188759 WITHDRAWN
Voriconazole And Anidulafungin Combination For Invasive Aspergillosis In Pediatric Subjects
Pfizer
NCT00531479 COMPLETED
Anidulafungin Plus Voriconazole Versus Voriconazole For The Treatment Of Invasive Aspergillosis
Pfizer n=459
NCT00689338 COMPLETED
Anidulafungin Candidemia/Invasive Candidiasis Intensive Care Study
Pfizer n=216
Data: ClinicalTrials.gov · Trials registered 2008 onwards · Industry sponsors only