TheraRadar
Landscape Cardiovascular

Heart Failure Clinical Trial Landscape

Data updated: May 20, 2026

1,181 clinical trials tracked since 2008

Heart failure is a chronic, progressive condition in which the heart is unable to pump enough blood to meet the body's needs. It affects millions worldwide and represents a significant area of unmet medical need. The clinical trial landscape for heart failure is active, with 1,167 trials registered since 2008, of which 269 are currently active and recruiting, enrolling, or active but not recruiting. Activity is distributed across all phases, with 52 active Phase 1, 102 active Phase 2, 69 active Phase 3, and 83 active Phase 4 trials. The greatest proportion of trials are in Phase 2. Industry sponsorship is led by Novo Nordisk with 5 active trials, followed by HELP Therapeutics Co., Ltd. with 4, and AstraZeneca and Tasly Pharmaceutical Group Co., Ltd, each with 3 active trials. Bayer currently sponsors 2 active trials.

275 active
/
1181 total (since 2008)
52
Phase 1 Active
238 total
103
Phase 2 Active
472 total
71
Phase 3 Active
278 total
85
Phase 4 Active
327 total

Top Industry Sponsors

Sorted by active Active Done Failed
Novo Nordisk 6 2 0
HELP Therapeutics Co., Ltd. 4 1 0
AstraZeneca 3 20 6
Tasly Pharmaceutical Group Co., Ltd 3 2 0
Bayer 2 24 4

+ 10 more sponsors — see full table below

Featured Phase 3 Trials

NCT06935370 RECRUITING
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
Boehringer Ingelheim n=4,200
NCT06424288 RECRUITING
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
Boehringer Ingelheim n=6,000
NCT07496372 RECRUITING
A Pivotal Clinical Trial of Human Induced Pluripotent Stem Cell-derived Cardiomyocytes Injection (HiCM-188) for the Treatment of Advanced Heart Failure(NYHA III-IV)
HELP Therapeutics Co., Ltd. n=80
NCT05714085 RECRUITING
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
Merck Sharp & Dohme LLC n=342
NCT06008197 RECRUITING
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
Colorado Prevention Center n=5,200

+ 273 more Phase 3 trials — see full database below

Heart Failure — Trials Started by Year (last 10 years)

2016
70
2017
74
2018
61
2019
48
2020
53
2021
76
2022
56
2023
67
2024
82
2025
84
2026
60

TheraRadar.com

Full Trial Database

Complete sponsor table, every trial across all phases, plus competitive analytics. Sortable, filterable, exportable for Pro users.

Top Sponsors (all-time)

Novo Nordisk
8
HELP Therapeutics Co., Ltd.
5
AstraZeneca
29
Tasly Pharmaceutical Group Co., Ltd
5
Bayer
30
Cytokinetics
13
Boehringer Ingelheim
8
Fujian Shengdi Pharmaceutical Co., Ltd.
3
Shandong Suncadia Medicine Co., Ltd.
2
Beijing Suncadia Pharmaceuticals Co., Ltd
2

Active Trials by Phase

Phase 1
52
Phase 2
103
Phase 3
71
Phase 4
85

Enrollment Size Distribution

1-50
477
51-200
357
201-500
143
501-1k
50
1k+
78

All Industry Sponsors

Sorted by active Active Done Failed
Novo Nordisk 6 2 0
HELP Therapeutics Co., Ltd. 4 1 0
AstraZeneca 3 20 6
Tasly Pharmaceutical Group Co., Ltd 3 2 0
Bayer 2 24 4
Cytokinetics 2 8 3
Boehringer Ingelheim 2 6 0
Fujian Shengdi Pharmaceutical Co., Ltd. 2 1 0
Shandong Suncadia Medicine Co., Ltd. 2 0 0
Beijing Suncadia Pharmaceuticals Co., Ltd 2 0 0
Heartseed Inc. 2 0 0
AskBio Inc 2 0 0
Sardocor Corp. 2 0 0
Novartis 1 35 8
Bristol-Myers Squibb 1 14 1
NCT06935370 RECRUITING
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
Boehringer Ingelheim n=4,200
NCT06424288 RECRUITING
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
Boehringer Ingelheim n=6,000
NCT07496372 RECRUITING
A Pivotal Clinical Trial of Human Induced Pluripotent Stem Cell-derived Cardiomyocytes Injection (HiCM-188) for the Treatment of Advanced Heart Failure(NYHA III-IV)
HELP Therapeutics Co., Ltd. n=80
NCT05714085 RECRUITING
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
Merck Sharp & Dohme LLC n=342
NCT07575672 NOT YET RECRUITING
Finerenone in Patients Undergoing Transcatheter Aortic Valve Implantation With Heart Failure
Second Affiliated Hospital, School of Medicine, Zhejiang University n=2,832
NCT07569640 NOT YET RECRUITING
HFrEF Polypill in Sri Lanka RCT
Washington University School of Medicine n=1,656
NCT06008197 RECRUITING
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
Colorado Prevention Center n=5,200
NCT06736574 RECRUITING
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
Cytokinetics n=1,800
NCT07037459 RECRUITING
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
Amgen n=5,056
NCT07567001 NOT YET RECRUITING
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
Novo Nordisk A/S n=5,610
NCT07018297 NOT YET RECRUITING
Early Discharge With Subcutaneous Furosemide Versus Standard Care in Acute Heart Failure
University of Texas Southwestern Medical Center n=250
NCT06405555 NOT YET RECRUITING
Midodrine in Heart Failure With Reduced Ejection Fraction With Hypotension
Ottawa Heart Institute Research Corporation n=56
NCT06307652 RECRUITING
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
AstraZeneca n=4,800
NCT07543562 RECRUITING
Selenium Intervention Registry Randomized Trial in Heart Failure
Skane University Hospital n=4,326
NCT06158698 RECRUITING
CMP-MYTHiC Trial and Registry - CardioMyoPathy With MYocarditis THerapy With Colchicine
Niguarda Hospital n=80
NCT07192952 NOT YET RECRUITING
A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction
Bayer n=117
NCT07188805 RECRUITING
A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction
Bayer n=111
NCT07234422 RECRUITING
The SELEQT-HF (SELEnium and CoQ10 NuTrition for Heart Failure) Study Will Evaluate the Effect of Adding Selenium/and coQ10 on Top of Standard HF Therapy in Patients With HF and Will do so Using a Pragmatic, Registry Based Randomized Controlled Trial in the Netherlands.
Netherlands Heart Institute n=1,100
NCT06200207 RECRUITING
A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation
Novo Nordisk A/S n=680
NCT06677060 RECRUITING
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
AstraZeneca n=11,300
NCT07038356 RECRUITING
Effects of Continued Administration of Empagliflozin in Patients With Heart Failure on Active SGLT2 Inhibitor Treatment Admitted for Acute Decompensated Heart Failure
Christian Schulze n=536
NCT07489547 RECRUITING
Medication Withdrawal in Stable HF With Improved LVEF
Hospital de Clinicas de Porto Alegre n=90
NCT06217302 RECRUITING
Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease
Alessandro Doria n=150
NCT07469722 NOT YET RECRUITING
POcus INTERvention for Tailoring Diuretic Strategy in Acute Decompensated Heart Failure
Hospital de Clinicas de Porto Alegre n=128
NCT07471139 NOT YET RECRUITING
SWITCH: Apixaban vs Vitamin K in HM3
Columbia University n=460
NCT05182658 ACTIVE NOT RECRUITING
Empagliflozin in Hypertrophic Cardiomyopathy
National Institute of Cardiology, Warsaw, Poland n=250
NCT05636176 RECRUITING
A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation
Novo Nordisk A/S n=5,600
NCT06578078 RECRUITING
A Clinical Trial to Define the Best Strategy for the Management of Heart Failure in Elderly Patients
Fundación para la Investigación del Hospital Clínico de Valencia n=94
NCT06128980 RECRUITING
Withdrawal of Treatment for Heart Failure Patients With Recovery From Tachycardia-induced Cardiomyopathy
Herlev and Gentofte Hospital n=348
NCT05825573 ACTIVE NOT RECRUITING
Anticoagulation Therapy in Non-device-related Intra-cardiac Thrombus
Centre Hospitalier Universitaire de Nīmes n=340
NCT05392764 RECRUITING
Early Treatment With a Sodium-glucose Co-transporter 2 Inhibitor in High-risk Patients With Acute Heart Failure
Juntendo University n=444
NCT07399587 RECRUITING
Optimizing HFrEF Patients Using BaroStim and CardioMems
Northwell Health n=15
NCT06518694 RECRUITING
Beta-blOckers discoNtinuation in Patients Presenting Heart FaIlure With REcovered Left Ventricular Ejection Fraction
Assistance Publique - Hôpitaux de Paris n=1,300
NCT06027307 ACTIVE NOT RECRUITING
Enavogliflozin Outcome Trial in Functional Tricuspid Regurgitation
Asan Medical Center n=541
NCT07288749 NOT YET RECRUITING
Efficacy Evaluation of Glimepiride in Patients With Type 2 Diabetes Mellitus and Chronic Heart Failure With Reduced Ejection Fraction.
Tongji Hospital n=1,484
NCT04982419 RECRUITING
Remote Ischemic Preconditioning for Renal and Cardiac Protection in Congestive Heart Failure (RICH) Trial
VA Office of Research and Development n=240
NCT00610051 NOT YET RECRUITING
ALP-1 Continuous Intravenous Infusion to Maintain Clinical Stability in Advanced Heart Failure
Biopeutics Co., Ltd n=600
NCT07270367 NOT YET RECRUITING
Finerenone and Cardiac Remodeling
Subodh Verma n=156
NCT07262723 NOT YET RECRUITING
Levosimendan in Acute Decompensated Heart Failure
Chittagong Medical College n=332
NCT05374291 ENROLLING BY INVITATION
The RENAL LIFECYCLE Trial: A RCT to Assess the Effect of Dapagliflozin on Renal and Cardiovascular Outcomes in Patients With Severe CKD
University Medical Center Groningen n=1,750
NCT06898515 RECRUITING
Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)
Reprieve Cardiovascular, Inc n=400
NCT07223242 RECRUITING
Tailored Exercise Training Study Among Adults With HFpEF
University of Texas Southwestern Medical Center n=120
NCT05887271 RECRUITING
A Randomised, Controlled Trial of a Low-energy Diet for Improving Functional Status in Heart Failure With PRESERVED Ejection Fraction Preserved Ejection Fraction
University of Leicester n=63
NCT06694727 RECRUITING
A Danish Pragmatic Randomized Trial of Nutritional Supplements in Heart Failure
Tor Biering-Sørensen n=4,044
NCT06349941 RECRUITING
Home-based Cardiac Rehabilitation in Heart Failure
University of Texas Southwestern Medical Center n=332
NCT07090343 NOT YET RECRUITING
Semaglutide in Patients Undergoing Transcatether Aortic Valve Replacement
Leiden University Medical Center n=826
NCT06929806 RECRUITING
Multi-center Trial of Ferric Derisomaltose Versus no Intravenous Iron in Iron-deficient Subjects With Symptomatic Chronic Heart Failure
Pharmacosmos A/S n=1,900
NCT06566183 NOT YET RECRUITING
International Study of Comparative Health Effectiveness With Medical and Invasive Approaches-Left Ventricular Dysfunction Trial
NYU Langone Health n=1,200
NCT05873881 RECRUITING
COLchicine and Thiamine in Heart Failure Due to Ischemic Heart Disease
Hamilton Health Sciences Corporation n=2,500
NCT07008365 RECRUITING
The Role of intraABDOminal Pressure and Point Of Care UltraSound to Guide Decongestive Therapy in Heart Failure
Instituto de Investigación Sanitaria Aragón n=168
NCT06946095 NOT YET RECRUITING
Efficacy and Safety of Xinyue Capsule in the Treatment of Heart Failure With Preserved Ejection Fraction
Beijing Anzhen Hospital n=246
NCT06033950 RECRUITING
A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients with Heart Failure Who Are Intolerant or Not Eligible for Treatment with Steroidal Mineralocorticoid Receptor Antagonists
Colorado Prevention Center n=2,600
NCT06024746 RECRUITING
A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients with Heart Failure (CONFIRMATION-HF)
Colorado Prevention Center n=1,500
NCT06837623 ACTIVE NOT RECRUITING
Role of Colchicine as Anti-Inflammatory Therapy in HFpEF
Cairo University n=75
NCT06619600 ACTIVE NOT RECRUITING
Effect of Dapagliflozin in Myocardial Fibrosis and Ventricular Function in Patients With a ST-segment Elevation Myocardial Infarction
Hospital Clinic of Barcelona n=54
NCT02984124 ACTIVE NOT RECRUITING
Communication During Hospitalization About Resuscitation Trial
University of Vermont n=182
NCT06783166 RECRUITING
Assessing the Clinical Outcomes of Dapagliflozin Versus Acetazolamide in Patients With Acute Heart Failure
Mansoura University n=100
NCT06082063 RECRUITING
Multifactorial Intervention to Reduce Cardiovascular Disease in Type 1 Diabetes
Steno Diabetes Center Copenhagen n=2,000
NCT06304857 RECRUITING
CardioPROTECTion with Dapagliflozin in Breast Cancer Patients Treated with AnthrAcycline - PROTECTAA TRIAL
4th Military Clinical Hospital with Polyclinic, Poland n=188
NCT06683053 ACTIVE NOT RECRUITING
Evaluation of the Use of Empagliflozin in Patients with HF with PEF in a Cardiology Outpatient Department
Conrado Roberto Hoffmann Filho n=90
NCT05508035 RECRUITING
The Effect of Sacubitril/valsartan Versus Ramipril on Left Ventricular Function and Remodeling in Patients with Ischemic Heart Failure with Mid-range Ejection Fraction
John Paul II Hospital, Krakow n=666
NCT02901184 RECRUITING
Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction
Uppsala University n=2,000
NCT06630923 RECRUITING
PREVENTION OF WORSENING RENAL FUNCTION OF INTRAVENUS ALBUMIN IN HEART FAILURE PATIENTS
Democritus University of Thrace n=250
NCT04201015 RECRUITING
Optimising Pacing for Contractility 2
University of Leeds n=400
NCT05824923 RECRUITING
A Trial to Evaluate the Safety and Efficacy of Pulmonary Artery Denervation for the Treatment of Pulmonary Hypertension Associated With Left Heart Failure
Pulnovo Medical (Wuxi) Co., Ltd. n=264
NCT06535529 RECRUITING
Acetazolamide Versus Dapagliflozin in Acute Decompensated Heart Failure Patients
Helwan University n=60
NCT06434025 NOT YET RECRUITING
IV Iron and SGLT2 Inhibitor on Ventricular Function and Myocardial Iron Content in Heart Failure With Iron Deficiency
Hospital de Clinicas de Porto Alegre n=99
NCT06423599 RECRUITING
Effect of Weight Loss on Physical and Cardiac Performance in People With Obesity and Heart Failure
Jens D Hove, MD,PHD n=100
NCT06142474 RECRUITING
SGLT2 Inhibitors in Patients With ADHF During Ventilator Weaning
National Taiwan University Hospital n=450
NCT05553886 RECRUITING
S086 Tablets for Chronic Heart Failure With Reduced Ejection Fraction
Shenzhen People's Hospital n=5
NCT07596329 NOT YET RECRUITING
Outpatient Hypertonic Saline and Loop Diuretic Combination Therapy in Cardiorenal
University of Monastir n=60
NCT05613218 COMPLETED
Oxygen Targets in Acute Heart Failure With Pulmonary Congestion
Copenhagen University Hospital, Hvidovre n=122
NCT05004363 COMPLETED
Lokelma for RAAS Maximisation in CKD & Heart Failure.
St George's, University of London n=112
NCT02032004 COMPLETED
Efficacy and Safety of Allogeneic Mesenchymal Precursor Cells (Rexlemestrocel-L) for the Treatment of Heart Failure
Mesoblast, Inc. n=565
NCT04158674 TERMINATED
Interest of Levosimendan in Reducing Weaning Failures of ExtraCorporeal Life Support - ECLS
Centre Hospitalier Universitaire Dijon n=82
NCT05668676 COMPLETED
Effect of Short-Term Prednisone Therapy on C-Reactive Protein Change in Emergency Department Patients With Acute Heart Failure and Elevated Inflammatory Markers ( CORTAHF )
Assistance Publique - Hôpitaux de Paris n=3
NCT05858320 COMPLETED
The Impact of an Adaptive Patient-centered Web Application on Medication Optimization in HFrEF Patients
University of Michigan n=225
NCT04551222 COMPLETED
The Re-Prosper HF Study
VA Office of Research and Development n=99
NCT05093933 COMPLETED
A Study of Vericiguat (MK-1242) in Participants With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF) (MK-1242-035)
Merck Sharp & Dohme LLC n=6,106
NCT04916470 COMPLETED
Research Study to Look at How Well Semaglutide Works in People Living With Heart Failure, Obesity and Type 2 Diabetes
Novo Nordisk A/S n=617
NCT01648634 COMPLETED
Nebivolol for the Prevention of Left Ventricular Systolic Dysfunction in Patients With Duchenne Muscular Dystrophy
Assistance Publique - Hôpitaux de Paris n=51
NCT03296813 COMPLETED
TRANSFORM-HF: ToRsemide compArisoN With furoSemide FORManagement of Heart Failure
Duke University n=2,973
NCT06149104 COMPLETED
A Safety Study of Sacubitril/Valsartan in Japanese Pediatric Patients With Heart Failure Due to Systemic Left Ventricle Systolic Dysfunction Who Have Completed CLCZ696B2319E1 Study
Novartis Pharmaceuticals n=8
NCT02438306 COMPLETED
CardiAMP™ Cell Therapy for Heart Failure Trial
BioCardia, Inc. n=125
NCT04986202 COMPLETED
Study to Evaluate the Efficacy and Safety of AZD4831 in Participants With Heart Failure With Left Ventricular Ejection Fraction > 40%
AstraZeneca n=711
NCT04435626 COMPLETED
Study to Evaluate the Efficacy (Effect on Disease) and Safety of Finerenone in Participants With Heart Failure and Left Ventricular Ejection Fraction (Proportion of Blood Expelled Per Heart Stroke) Greater or Equal to 40%
Bayer n=6,016
NCT04847557 COMPLETED
A Study of Tirzepatide (LY3298176) in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF) and Obesity: The SUMMIT Trial
Eli Lilly and Company n=731
NCT05676684 COMPLETED
Dapagliflozin With or Without Spironolactone for HFpEF
Universidade do Porto n=108
NCT05237323 COMPLETED
Micophenolate Mofetil Versus Azathioprine in Myocarditis
I.M. Sechenov First Moscow State Medical University n=50
NCT07023016 COMPLETED
Comparative Assessment of Efficacy & Safety of Sacubitril/Valsartan Versus Ramipril in Patients With Renal Dysfunction Hospitalized With Acute Decompensated Heart Failure
National Heart Institute, Egypt n=515
NCT04600921 TERMINATED
Ertugliflozin to Reduce Arrhythmic Burden in ICD/CRT patientS (ERASe-Trial) - a Phase III Study
Medical University of Graz n=55
NCT03341156 TERMINATED
Administration of Prothrombin Complex Concentrate vs. Standard Transfusion During/After Heart Transplantation
University of Maryland, Baltimore n=14
NCT03833336 COMPLETED
Effects of Iron Therapy in Heart Failure With Preserved Ejection Fraction and Iron Deficiency (PREFER-HF)
Institut de Recerca Biomèdica de Lleida n=72
NCT03785405 COMPLETED
Open-label Extension Study to Evaluate Long-term Safety of Sacubitril/Valsartan in Pediatric Patients With HF
Novartis Pharmaceuticals n=216
NCT04536272 COMPLETED
Reduced Anticoagulation Targets in ECLS (RATE)
University Medical Center Groningen n=330
NCT04252287 COMPLETED
A Study on Impact of Canagliflozin on Health Status, Quality of Life, and Functional Status in Heart Failure
Janssen Research & Development, LLC n=476
NCT04727073 TERMINATED
Spironolactone in the Treatment of Heart Failure
Charite University, Berlin, Germany n=743
NCT04564742 COMPLETED
Dapagliflozin Effects on Cardiometabolic Outcomes in Patients With an Acute Heart Attack.
AstraZeneca n=4,017
NCT03988634 COMPLETED
Changes in NT-proBNP, Safety, and Tolerability in HFpEF Patients With a WHF Event (HFpEF Decompensation) Who Have Been Stabilized and Initiated at the Time of or Within 30 Days Post-decompensation (PARAGLIDE-HF)
Novartis Pharmaceuticals n=467
NCT05652322 WITHDRAWN
Prolonged Intravenous Therapy Versus Early Initiation of an Oral Loop Diuretic in Decompensated Heart Failure
Jan Kochanowski University
NCT05949801 COMPLETED
Evaluation of the Effect of Injectable Neucardin on Cardiac Function and Reversal Ventricular Remodeling in Patients With Chronic Systolic Heart Failure
Zensun Sci. & Tech. Co., Ltd. n=202
NCT03717194 COMPLETED
Effect of Ertugliflozin on Cardiac Function in Diabetes
Soo Lim n=102
NCT05043610 COMPLETED
MSCs for Prevention of MI-induced HF
Shiraz University of Medical Sciences n=420
NCT05093621 COMPLETED
Torsemide Comparison With Furosemide for Management of Patients With Stable Heart Failure
Yale University n=47
NCT04755816 TERMINATED
A Mobile Application to Promote Self-management and Improve Outcomes in Heart Failure
University of Michigan n=62
NCT03255226 COMPLETED
Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics Study of Tolvaptan in Pediatric Congestive Heart Failure (CHF) Patients With Volume Overload
Otsuka Pharmaceutical Co., Ltd. n=60
NCT02884206 COMPLETED
Efficacy and Safety of LCZ696 Compared to Valsartan on Cognitive Function in Patients With Chronic Heart Failure and Preserved Ejection Fraction
Novartis Pharmaceuticals n=592
NCT04468529 COMPLETED
Evaluate the Effect of Injectable Neucardin on the Cardiac Function of Subjects With Chronic Systolic Heart Failure
Zensun Sci. & Tech. Co., Ltd. n=154
NCT05364190 COMPLETED
Canagliflozin in Patients With Acute Decompansted Heart Failure
October 6 University n=142
NCT03037931 COMPLETED
Randomized Placebo-controlled Trial of FCM as Treatment for Heart Failure With Iron Deficiency / and Sub-Study
American Regent, Inc. n=3,065
NCT05962255 COMPLETED
Sodium Chloride vs. Glucose Solute as a Volume Replacement Therapy During Decongestion in Acute Heart Failure
Wroclaw Medical University n=50
NCT04705987 COMPLETED
Randomized Double-blind Trial to Study the Benefit of Colchicine in Patients With Acutely Decompensated Heart Failure
Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia n=279
NCT04298229 COMPLETED
Efficacy and Safety of Dapagliflozin in Acute Heart Failure
Vanderbilt University Medical Center n=240
NCT03917459 COMPLETED
COmparing arNi and Ace For Improving Erectile Dysfunction in mEN With reduCed Ejection Fraction Heart Failure
Novartis Pharmaceuticals n=27
NCT04415658 COMPLETED
Intravenous Thyroxine for Heart-Eligible Organ Donors
Washington University School of Medicine n=838
NCT03991000 TERMINATED
Iron in Patients With Cardiovascular Disease
Dr. med. Mahir Karakas n=8
NCT02468232 COMPLETED
Study of Efficacy and Safety of LCZ696 in Japanese Patients With Chronic Heart Failure and Reduced Ejection Fraction
Novartis Pharmaceuticals n=225
NCT02592824 COMPLETED
Glutamate for Metabolic Intervention in Coronary Surgery II
University Hospital, Linkoeping n=321
NCT01005303 COMPLETED
Micronutrient Supplementation in Patients With Heart Failure
Belfast Health and Social Care Trust n=79
NCT04533997 COMPLETED
Hypertonic Saline Therapy in Ambulatory Heart Failure Unit.
Puerta de Hierro University Hospital n=167
NCT04738279 COMPLETED
The CASCADE HF Soft Launch and Calibration Phase I and II
Endeavor Health n=20
NCT00709865 COMPLETED
Study to Assess the Safety and Tolerability of IV Tonapofylline in Subjects With Acute Decompensated Heart Failure (ADHF) and Renal Insufficiency
Biogen n=420
NCT05406505 COMPLETED
Effect of Dapagliflozin in Patients With Acute Heart Failure (DAPA-RESPONSE-AHF)
Mansoura University n=87
NCT03745898 TERMINATED
The Impact of Low Flow Nocturnal Oxygen Therapy on Hospital Admissions and Mortality in Patients With Heart Failure and Central Sleep Apnea
Brigham and Women's Hospital n=98
NCT04707352 COMPLETED
Impact on Atrial Remodeling of Dapaglifozin in Patients With Heart Failure .
Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia n=162
NCT03619213 COMPLETED
Dapagliflozin Evaluation to Improve the LIVEs of Patients With PReserved Ejection Fraction Heart Failure.
AstraZeneca n=6,263
NCT03552575 COMPLETED
The Effects of Sacubitril/Valsartan Compared to Valsartan on LV Remodelling in Asymptomatic LV Systolic Dysfunction After MI
NHS Greater Glasgow and Clyde n=93
NCT03759392 COMPLETED
Study to Assess the Effect of Omecamtiv Mecarbil on Exercise Capacity in Subjects With Heart Failure
Cytokinetics n=276
NCT03458325 COMPLETED
Furoscix Real-World Evaluation for Decreasing Hospital Admissions in Heart Failure
scPharmaceuticals, Inc. n=27
NCT02678312 COMPLETED
Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LCZ696 Followed by a 52-week, Double-blind Study of LCZ696 Compared With Enalapril in Pediatric Patients With Heart Failure
Novartis Pharmaceuticals n=393
NCT02012179 COMPLETED
SODIUM-HF: Study of Dietary Intervention Under 100 MMOL in Heart Failure
University of Alberta n=806
NCT04507347 WITHDRAWN
Efficacy and Safety of TRC041266 in Patients With Heart Failure, LVEF ≥40%, Diastolic Dysfunction and Type 2 Diabetes Mellitus
Torrent Pharmaceuticals Limited
NCT02329834 COMPLETED
Crossover Study to Compare the Pharmacokinetics and Bioavailability of a Novel Furosemide Regimen Administered Subcutaneously vs. the Same Dose Administered Intravenously in Subjects With Chronic Heart Failure
scPharmaceuticals, Inc. n=23
NCT03521934 TERMINATED
Effect of Sotagliflozin on Cardiovascular Events in Participants With Type 2 Diabetes Post Worsening Heart Failure (SOLOIST-WHF Trial)
Lexicon Pharmaceuticals n=1,222
NCT03315143 TERMINATED
Effect of Sotagliflozin on Cardiovascular and Renal Events in Participants With Type 2 Diabetes and Moderate Renal Impairment Who Are at Cardiovascular Risk
Lexicon Pharmaceuticals n=10,584
NCT03884504 COMPLETED
MDT-1118 Japan DT Study
Medtronic Cardiac Rhythm and Heart Failure n=10
NCT03359161 TERMINATED
Clinical Utility of Subcutaneous Furosemide in Patients Presenting With Early Signs of Fluid Overload
Steward St. Elizabeth's Medical Center of Boston, Inc. n=9
NCT01586442 COMPLETED
Comparison of Eplerenone Versus Spironolactone in Heart Failure Patients With Glucose Intolerance or Type 2 Diabetes
Montreal Heart Institute n=62
NCT02674438 COMPLETED
Comparison of Outcomes and Access to Care for Heart Failure Trial
Institute for Clinical Evaluative Sciences n=5,452
NCT01647932 COMPLETED
Safety and Efficacy of the Combination of Loop With Thiazide-type Diuretics in Patients With Decompensated Heart Failure
Spanish Society of Internal Medicine n=232
NCT01759212 TERMINATED
Left Ventricular Assist Device Combined With Allogeneic Mesenchymal Stem Cells Implantation in Patients With End-stage Heart Failure.
AHEPA University Hospital n=1
NCT01565941 COMPLETED
Heart And Lung Failure - Pediatric INsulin Titration Trial
Boston Children's Hospital n=713
NCT04157751 COMPLETED
A Study to Test the Effect of Empagliflozin in Patients Who Are in Hospital for Acute Heart Failure
Boehringer Ingelheim n=530
NCT03057951 COMPLETED
EMPagliflozin outcomE tRial in Patients With chrOnic heaRt Failure With Preserved Ejection Fraction (EMPEROR-Preserved)
Boehringer Ingelheim n=5,988
NCT01210365 TERMINATED
Safety and Efficacy of Furosemide 40mg + Amiloride Hydrochloride 10mg to Reduct Edema
Eurofarma Laboratorios S.A. n=27
NCT02809131 COMPLETED
Perioperative Antibiotic Therapy to Prevent Cardiac Implantable Electronic Device Infections.
Vanderbilt University Medical Center n=1,010
NCT03926754 COMPLETED
Beta 3 Agonist Treatment in Heart Failure-2
Henning Bundgaard n=56
NCT02271230 COMPLETED
Intervention With Vitamin D and Omega-3 Supplements and Incident Heart Failure
Brigham and Women's Hospital n=25,871
NCT03877224 COMPLETED
DETERMINE-preserved - Dapagliflozin Effect on Exercise Capacity Using a 6-minute Walk Test in Patients With Heart Failure With Preserved Ejection Fraction
AstraZeneca n=504
NCT02861534 COMPLETED
A Study of Vericiguat in Participants With Heart Failure With Reduced Ejection Fraction (HFrEF) (MK-1242-001)
Merck Sharp & Dohme LLC n=5,050
NCT02929329 COMPLETED
Registrational Study With Omecamtiv Mecarbil (AMG 423) to Treat Chronic Heart Failure With Reduced Ejection Fraction
Cytokinetics n=8,256
NCT03066804 COMPLETED
A Randomized, Double-blind Controlled Study Comparing LCZ696 to Medical Therapy for Comorbidities in HFpEF Patients
Novartis Pharmaceuticals n=2,572
NCT03909295 TERMINATED
An Open-label Extension Study Evaluating Safety and Tolerability of LCZ696 in Subjects Who Completed PARAGON-HF in Japan.
Novartis Pharmaceuticals n=52
NCT03962101 COMPLETED
Safety Trial of OPC-61815 Injection in Patients With Congestive Heart Failure Who Have Difficulty With or Are Incapable of Oral Intake
Otsuka Pharmaceutical Co., Ltd. n=45
NCT04128891 WITHDRAWN
Study of Sacubitril/ValsarTan on MyocardIal OxygenatioN and Fibrosis in Heart Failure With Preserved Ejection Fraction
Flinders University
NCT03772041 COMPLETED
Efficacy and Safety Trial of OPC-61815 Injection Compared With Tolvaptan 15-mg Tablet in Patients With Congestive Heart Failure
Otsuka Pharmaceutical Co., Ltd. n=294
NCT04464525 WITHDRAWN
Omecamtiv Mecarbil Post-trial Access Study
Cytokinetics
NCT03332212 COMPLETED
A Study That Looks at the Function of the Heart in Patients With Heart Failure Who Take Empagliflozin
Boehringer Ingelheim n=72
NCT03057977 COMPLETED
EMPagliflozin outcomE tRial in Patients With chrOnic heaRt Failure With Reduced Ejection Fraction (EMPEROR-Reduced)
Boehringer Ingelheim n=3,730
NCT03877237 COMPLETED
DETERMINE-reduced - Dapagliflozin Effect on Exercise Capacity Using a 6-minute Walk Test in Patients With Heart Failure With Reduced Ejection Fraction
AstraZeneca n=313
NCT01583881 TERMINATED
Denervation of the renAl sympathetIc nerveS in hearT Failure With nOrmal Lv Ejection Fraction
UMC Utrecht n=60
NCT01535196 TERMINATED
Vitamine D Treatment in Chronic Heart Failure
Semmelweis University n=8
NCT03418233 COMPLETED
Randomized Clinical Trial to Evaluate the Regenerative Capacity of CardioCell in Patients With Chronic Ischaemic Heart Failure (CIHF)
John Paul II Hospital, Krakow n=115
NCT02708771 COMPLETED
Effect of W-3 Polyunsaturated Fatty Acids on Serum Albumin Concentration in Patients With Acute Heart Failure, Hypoalbuminemia, and High Inflammatory Activity
Hospital San Juan de la Cruz n=42
NCT01115855 COMPLETED
Clinical Study Of Eplerenone In Japanese Patients With Chronic Heart Failure
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. n=221
NCT01534663 COMPLETED
Supplementation of Glutamine and Fish Oil Versus Placebo in Patients With Heart Failure
Columbia University n=31
NCT03448406 COMPLETED
This Study Tests Empagliflozin in Patients With Chronic Heart Failure With Preserved Ejection Fraction (HFpEF). The Study Looks at How Far Patients Can Walk in 6 Minutes and at Their Heart Failure Symptoms.
Boehringer Ingelheim n=315
NCT03448419 COMPLETED
This Study Tests Empagliflozin in Patients With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF). The Study Looks at How Far Patients Can Walk in 6 Minutes and at Their Heart Failure Symptoms
Boehringer Ingelheim n=312
NCT04628325 COMPLETED
Effects of Furosemide Plus Small HSS in Subjects With Heart Failure With Reduced Ejection Fraction (HFrEF)
University of Palermo n=136
NCT03037580 TERMINATED
Oral Treprostinil in Subjects With Pulmonary Hypertension Associated With Heart Failure With Preserved Ejection Fraction
United Therapeutics n=84
NCT04592380 WITHDRAWN
Clevidipine vs Placebo or Standard of Care for Dyspnea and Blood Pressure Control in AHF
The Medicines Company
NCT01920711 COMPLETED
Efficacy and Safety of LCZ696 Compared to Valsartan, on Morbidity and Mortality in Heart Failure Patients With Preserved Ejection Fraction
Novartis Pharmaceuticals n=4,822
NCT02900378 COMPLETED
randOmized stUdy Using acceleromeTry to Compare Sacubitril/valsarTan and Enalapril in Patients With Heart Failure
Novartis Pharmaceuticals n=621
NCT03036124 COMPLETED
Study to Evaluate the Effect of Dapagliflozin on the Incidence of Worsening Heart Failure or Cardiovascular Death in Patients With Chronic Heart Failure
AstraZeneca n=4,744
NCT02044211 COMPLETED
Blended Collaborative Care for Heart Failure and Co-Morbid Depression
University of Pittsburgh n=756
NCT02598505 COMPLETED
Indacaterol in Heart Failure Patients: Any Role on Lung Fluid Regulation
Centro Cardiologico Monzino n=44
NCT02869022 COMPLETED
Study of Organ Perfusion With Custodiol-N Solution Compared With Custodiol Solution in Heart Transplantation
Dr. F. Köhler Chemie GmbH n=105
NCT02111564 COMPLETED
A Study of Rivaroxaban (JNJ-39039039) on the Venous Thromboembolic Risk in Post-Hospital Discharge Patients
Janssen Research & Development, LLC n=12,024
NCT01124227 TERMINATED
Peritoneal Dialysis in Congestive Heart Failure
Martini Hospital Groningen n=26
NCT02585843 COMPLETED
Mineralocorticoid Receptor Antagonists (MRA) in Heart Failure (HF) and Loop Diuretic Resistance
Columbia University n=20
NCT02007720 TERMINATED
Efficacy, Safety and Tolerability of Sexelaxin When Added to Standard Therapy in AHF
Novartis Pharmaceuticals n=876
NCT02488525 TERMINATED
Prevention of Hemorrhage After Implantation of Mechanical Circulatory Support
University Hospital, Lille n=31
NCT03360448 WITHDRAWN
AC6 Gene Transfer in Patients With Reduced Left Ventricular Ejection Fraction Heart Failure
Renova Therapeutics
NCT02656329 TERMINATED
International Study to Determine if AdreView Heart Function Scan Can be Used to Identify Patients With Mild or Moderate Heart Failure (HF) That Benefit From Implanted Medical Device
GE Healthcare n=395
NCT01877915 COMPLETED
A Study to Assess the Effectiveness and Safety of Rivaroxaban in Reducing the Risk of Death, Myocardial Infarction or Stroke in Participants With Heart Failure and Coronary Artery Disease Following an Episode of Decompensated Heart Failure
Janssen Research & Development, LLC n=5,081
NCT02064868 TERMINATED
Effect of Serelaxin Versus Standard of Care in Acute Heart Failure (AHF) Patients
Novartis Pharmaceuticals n=2,666
NCT02885636 COMPLETED
Inhaled Beta-adrenergic Agonists to Treat Pulmonary Vascular Disease in Heart Failure With Preserved EF (BEAT HFpEF): A Randomized Controlled Trial
Mayo Clinic n=30
NCT02226120 COMPLETED
Safety and Tolerability During Open-label Treatment With LCZ696 in Patients With CHF and Reduced Ejection Fraction
Novartis Pharmaceuticals n=1,980
NCT02620384 TERMINATED
Metolazone As Early Add On Therapy For Acute Decompensated Heart Failure (MELT-HF)--A Single Center Pilot Study.
Aultman Health Foundation n=147
NCT01362725 COMPLETED
Spinal Cord Stimulation For Heart Failure
Abbott Medical Devices n=20
NCT01786993 COMPLETED
MultiPoint Pacing IDE Study
Abbott Medical Devices n=506
NCT00679484 TERMINATED
Study to Demonstrate the Non-inferiority of Olmesartan Medoxomil Versus Candesartan Cilexetil in Reducing Blood B-type (or Brain) Natriuretic Peptide Levels at Week 24
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company n=400
NCT01661634 COMPLETED
Efficacy and Safety of Ularitide for the Treatment of Acute Decompensated Heart Failure
Cardiorentis n=2,157
NCT02129764 COMPLETED
Prednisone for Heart Failure Patients With Hyperuricemia
Hebei Medical University n=205
NCT03102827 TERMINATED
High-Flow-Therapy for the Treatment of Cheyne-Stokes-Respiration in Chronic Heart Failure
Heart and Diabetes Center North-Rhine Westfalia n=14
NCT01215253 COMPLETED
Ranolazine Implantable Cardioverter-Defibrillator Trial
University of Rochester n=1,012
NCT01878630 COMPLETED
Telemedical Interventional Management in Heart Failure II
Charite University, Berlin, Germany n=1,571
NCT01439529 COMPLETED
ECG Optimization of CRT: Evaluation of Mid-term Response
Hospital Clinic of Barcelona n=180
NCT03592836 COMPLETED
Diuretic Response in Advanced Heart Failure: Bolus Intermittent vs Continuous INfusion
University of Turin, Italy n=80
NCT02804282 COMPLETED
Product Design Clinical Performance Study of sc2Wear Furosemide Combination Product
scPharmaceuticals, Inc. n=74
NCT01768702 COMPLETED
Safety and Efficacy of Autologous Cardiopoietic Cells for Treatment of Ischemic Heart Failure.
Celyad Oncology SA n=315
NCT00608140 TERMINATED
Effectiveness of Surgical Mitral Valve Repair Versus Medical Treatment for People With Significant Mitral Regurgitation and Non-ischemic Congestive Heart Failure
Duke University n=2
NCT01870778 COMPLETED
Efficacy, Safety and Tolerability of Serelaxin When Added to Standard Therapy in AHF
Novartis Pharmaceuticals n=6,600
NCT01690091 COMPLETED
Cardioprotective and Metabolic Effects of Metformin in Patients With Heart Failure and Diabetes
Institute for Clinical and Experimental Medicine n=40
NCT00577135 COMPLETED
Determining Optimal Dose and Duration of Diuretic Treatment in People With Acute Heart Failure (The DOSE-AHF Study)
Duke University n=308
NCT01724450 COMPLETED
Carvedilol Effect in Preventing Chemotherapy - Induced Cardiotoxicity
University of Sao Paulo n=200
NCT01217307 COMPLETED
Metformin to Reduce Heart Failure After Myocardial Infarction
University Medical Center Groningen n=380
NCT02248532 COMPLETED
Repetitive Intramyocardial CD34+ Cell Therapy in Dilated Cardiomyopathy (REMEDIUM)
University Medical Centre Ljubljana n=66
NCT00683696 TERMINATED
Echocardiography Guided Cardiac Resynchronization Therapy (EchoCRT)
Biotronik, Inc. n=1,680
NCT01936909 COMPLETED
Interleukin-1 Blockade in Recently Decompensated Heart Failure
Virginia Commonwealth University n=60
NCT00384657 WITHDRAWN
Intravenous Iron in Patients With Severe Chronic Heart Failure and Chronic Kidney Disease
Anemia Working Group Romania
NCT01214096 TERMINATED
Clinical Trial to Evaluate the Efficacy and Safety of Recombinant Human Neuregulin-1 for Subcutaneous Administration in Patients With Chronic Systolic Heart Failure
Zensun Sci. & Tech. Co., Ltd. n=15
NCT01541202 TERMINATED
Study of the Survival of Recombinant Human Neuregulin-1β in Chronic Heart Failure (CHF) Patients
Zensun Sci. & Tech. Co., Ltd. n=679
NCT01439789 TERMINATED
Study of Efficacy on NT-proBNP of Recombinant Human Neuregulin-1 in Chronic Heart Failure Patients
Zensun Sci. & Tech. Co., Ltd. n=146
NCT01131637 TERMINATED
Study of the Survival of Recombinant Human Neuregulin-1β in Chronic Heart Failure (CHF) Patients
Zensun Sci. & Tech. Co., Ltd. n=331
NCT01439893 TERMINATED
Study of Efficacy on Cardiac Remodeling of Recombinant Human Neuregulin-1 in Stable Chronic Systolic Heart Failure Patients
Zensun Sci. & Tech. Co., Ltd. n=14
NCT02579057 COMPLETED
Sub-Q Versus IV Furosemide in Acute Heart Failure
Johns Hopkins University n=40
NCT01160978 COMPLETED
Donor Simvastatin Treatment in Organ Transplantation
Helsinki University Central Hospital n=84
NCT01960153 WITHDRAWN
Phosphodiesterase Type 5 Inhibition With Tadalafil Changes Outcomes in Heart Failure: Extent of Renal Damage
Massachusetts General Hospital
NCT03262571 TERMINATED
Usefulness of Lung Ultrasound in Ambulatory Management of Patients With Chronic Heart Failure
IRCCS San Raffaele n=244
NCT02188784 COMPLETED
Oral Iron Repletion Effects On Oxygen Uptake in Heart Failure
Adrian Hernandez n=225
NCT01286116 TERMINATED
A Multinational Trial To Evaluate The Parachute Implant System
CardioKinetix, Inc n=59
NCT01614652 TERMINATED
A Pivotal Trial to Establish the Efficacy and Long-term Safety of the Parachute Implant System
CardioKinetix, Inc n=331
NCT01394562 COMPLETED
Effect of Ferric Carboxymaltose on Exercise Capacity in Patients With Iron Deficiency and Chronic Heart Failure
Vifor Pharma n=174
NCT02047448 COMPLETED
Improving Medication Adherence Through a Transitional Care Pharmacy Practice Model
Wilkes University n=180
NCT01644331 COMPLETED
Targeting Acute Congestion With Tolvaptan in Congestive Heart Failure
Duke University n=257
NCT02043522 COMPLETED
123I-mIBG SPECT Imaging
Ottawa Heart Institute Research Corporation n=30
NCT01290146 TERMINATED
ELEVATE Early LEvosimendan Vs Usual Care in Advanced Chronic hearT failurE
Niguarda Hospital n=13
NCT01311791 COMPLETED
A Randomized, Controlled Study to Evaluate Algisyl-LVR™ as a Method of Left Ventricular Augmentation for Heart Failure
LoneStar Heart, Inc. n=78
NCT00543881 COMPLETED
Telemedical Interventional Monitoring in Heart Failure
Charite University, Berlin, Germany n=710
NCT02998697 COMPLETED
Short Term Oral Iron Supplementation in Systolic Heart Failure Patients Suffering From Iron Deficiency Anemia
National Cardiovascular Center Harapan Kita Hospital Indonesia n=54
NCT00853658 COMPLETED
Efficacy and Safety of Aliskiren and Aliskiren/Enalapril Combination on Morbidity-mortality in Patients With Chronic Heart Failure
Novartis Pharmaceuticals n=7,064
NCT01584557 COMPLETED
Randomized, Double-Blind, Placebo Controlled Study of the Short Term Clinical Effects of Tolvaptan in Patients Hospitalized for Worsening Heart Failure With Challenging Volume Management
Cardiovascular Clinical Sciences Inc n=250
NCT01035255 TERMINATED
This Study Will Evaluate the Efficacy and Safety of LCZ696 Compared to Enalapril on Morbidity and Mortality of Patients With Chronic Heart Failure
Novartis Pharmaceuticals n=8,442
NCT00944229 TERMINATED
The Effect of Omega-3 Polyunsaturated Fatty Acids in Congestive Heart Failure
Columbia University n=58
NCT01837082 TERMINATED
Iron in Congestive Heart Failure
University of Ulm n=18
NCT01936844 COMPLETED
Interleukin (IL)-1 Blockade in Acute Heart Failure (Anakinra ADHF)
Virginia Commonwealth University n=30
NCT01698242 COMPLETED
The Congestive Heart Failure Adherence Redesign Trial
Lynda Powell, PhD, MEd n=320
NCT00814840 COMPLETED
Efficiency Study of Triple-Site Cardiac Resynchronization in Patients With Heart Failure
Silesian Centre for Heart Diseases n=100
NCT01726049 COMPLETED
Sildenafil in HFpEF (Heart Failure With Preserved Ejection Fraction) and PH
University Medical Center Groningen n=52
NCT00746954 TERMINATED
Buspirone as a Potential Treatment for Recurrent Central Apnea
VA Office of Research and Development n=8
NCT01303718 TERMINATED
INcrease Of VAgal TonE in CHF
BioControl Medical n=730
NCT00399594 COMPLETED
Effect of Targeting Left Ventricular Lead Position on the Rate of Response to Cardiac Resynchronization Therapy.
University of Calgary n=96
NCT01472237 TERMINATED
Nutritional Intervention Program in Malnourished Patients Admitted for Heart Failure
Hospital San Juan de la Cruz n=120
NCT01844037 TERMINATED
OneShot Renal Denervation Registry
Medtronic Endovascular n=51
NCT00604006 COMPLETED
SCREEN-HFI (SCReening Evaluation of the Evolution of New Heart Failure Intervention Study)
Monash University n=20
NCT00821717 TERMINATED
EFfect of Ferric Carboxymaltose on exercIse CApacity and Cardiac Function in Patients With Iron deficiencY and Chronic Heart Failure
Vifor Pharma n=35
NCT01910389 TERMINATED
Phosphodiesterase Type 5 Inhibition With Tadalafil Changes Outcomes in Heart Failure
Carelon Research n=23
NCT01437371 COMPLETED
Is There a Benefit to Optimize Heart Failure (HF) Treatment in Aged Over 80 Year's Old Patients?
University Hospital, Clermont-Ferrand n=35
NCT01178528 COMPLETED
Heart Rate Reduction in Heart Failure
IRCCS San Raffaele n=121
NCT00803634 COMPLETED
Clevidipine in the Treatment of Blood Pressure in Patients With Acute Heart Failure (PRONTO)
The Medicines Company n=117
NCT00763867 COMPLETED
Evaluating the Effectiveness of Sildenafil at Improving Health Outcomes and Exercise Ability in People With Diastolic Heart Failure (The RELAX Study)
Duke University n=216
NCT00820352 COMPLETED
Safety and Efficacy of Bosentan in Patients With Diastolic Heart Failure and Secondary Pulmonary Hypertension
University Teaching Hospital Hall in Tirol n=20
NCT02167789 COMPLETED
Clinical Evaluation of the Physiological Diagnosis Function in the PARADYM CRT Device
LivaNova n=520
NCT01169272 COMPLETED
Clinical Evaluation Of The SonR Atrial Lead In Paradym RF Device
LivaNova n=100
NCT01193634 COMPLETED
Clinical Evaluation Of The PARADYM RF Device
LivaNova n=75
NCT01255475 COMPLETED
Blood Pressure Reduction in Heart Failure
University of Sao Paulo n=21
NCT01292720 COMPLETED
Vitamin D Supplementation in Chronic Stable Heart Failure
Medical University of Graz n=29
NCT00843986 TERMINATED
Safety and Efficacy of Conivaptan in Hyponatremic Patients With Symptomatic Acute Decompensated Heart Failure (ADHF)
Cumberland Pharmaceuticals n=9
NCT01872234 TERMINATED
MADIT ASIA Cardiac Resynchronization Trial
Boston Scientific Corporation n=1
NCT01646515 TERMINATED
Udenafil Therapy to Improve Symptomatology, Exercise Tolerance and Hemodynamics in Patients With Chronic Systolic Heart Failure
Seoul National University Hospital n=41
NCT00372762 WITHDRAWN
Bumetanide Versus Furosemide in Heart Failure
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
NCT00699361 WITHDRAWN
Influence of Pantoprazole on Human Myocardial Contractility at Patients With Congestive Heart Failure
Johann Wolfgang Goethe University Hospital
NCT01936350 COMPLETED
Sildenafil Impact on Ventricular Function in Patients With Heart Failure
Hospital Ana Nery n=24
NCT00894387 COMPLETED
Six Months Efficacy and Safety of Aliskiren Therapy on Top of Standard Therapy, on Morbidity and Mortality in Patients With Acute Decompensated Heart Failure
Novartis Pharmaceuticals n=1,639
NCT01375361 WITHDRAWN
Nebulized Albuterol for Congestive Heart Failure Exacerbation
University of California, San Francisco
NCT01559727 COMPLETED
Dose-comparison Study of Prednisone in Heart Failure
Hebei Medical University n=40
NCT01538992 WITHDRAWN
Renal Denervation in Patients With Advanced Heart Failure
Bursa Postgraduate Hospital
NCT00887237 COMPLETED
Triple Site Ventricular Stimulation for Cardiac Resynchronization Therapy (CRT) Candidates
Medtronic Cardiac Rhythm and Heart Failure n=76
NCT00608491 COMPLETED
Effectiveness of Ultrafiltration in Treating People With Acute Decompensated Heart Failure and Cardiorenal Syndrome (The CARRESS Study)
Duke University n=188
NCT00810238 COMPLETED
C-Cure Clinical Trial
Celyad Oncology SA n=240
NCT01580553 COMPLETED
The Clinical Study of the Efficacy and Safety of L-Carnitine Injection in Treatment of Heart Failure
Lee's Pharmaceutical Limited n=268
NCT00953303 COMPLETED
The Effects of Glucocorticoids on Mortality and Renal Function in Patients With Acute Decompensated Heart Failure
Hebei Medical University n=102
NCT01028170 COMPLETED
Safety and Efficacy of Low Dose Hypertonic Saline Solution and High Dose Furosemide for Congestive Heart Failure
Aspirus Heart and Vascular Institute-Research and Education n=50
NCT01138683 COMPLETED
Cardiorenal Interactions During Treatment of Acute Decompensated Heart Failure: Diuretics Versus Ultrafiltration
University Hospital, Ghent n=1
NCT00815386 SUSPENDED
Safety and Efficacy Study of the PTMA Device to Reduce Mitral Valve Regurgitation in Patients With Heart Failure
Viacor n=20
NCT01115504 COMPLETED
Thiamine Supplementation in Heart Failure Patients Receiving Full Medical Therapy
Mashhad University of Medical Sciences n=50
NCT00775840 COMPLETED
Efficacy of Candesartan on Symptomatic Heart Failure in Treating Diabetic and Hypertensive Patients.
Takeda n=22

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Data: ClinicalTrials.gov · Trials registered 2008 onwards · Industry sponsors only