NCT06233331 NOT YET RECRUITING Use of ACU-D1 in HPV Associated Vulvar and Perianal Lesions in People With HIV
Emory University
NCT07481175 RECRUITING Inhibiting the Anti-apoptotic Factor, BCL-2, at the Time of ART Initiation to Promote Apoptosis of HIV-infected Cells and Restrict the Seeding of the HIV Reservoir (The INITIATE Study)
Thomas Aagaard Rasmussen
NCT06694753 RECRUITING Safety and Immunogenicity Study of Three mRNAs Encoding HIV Immunogens in Adult Participants Without HIV and in Overall Good Health in South Africa.
International AIDS Vaccine Initiative
NCT07569029 NOT YET RECRUITING A Trial to Evaluate the Safety and Tolerability of DV700P-RNA and DV701B1.1-RNA Immunization in Combination With Antiretroviral Analytical Treatment Interruption (ATI) in People Living With HIV for Elicitation of V3-glycan Antibodies
National Institute of Allergy and Infectious Diseases (NIAID)
NCT07042945 RECRUITING MK-4646 Multiple Dose Trial in Participants With Human Immunodeficiency Virus Type 1 (HIV-1) (MK-4646-003)
Merck Sharp & Dohme LLC
NCT05890963 ACTIVE NOT RECRUITING 10E8.4/iMab Bispecific Antibody and VRC07-523LS Monoclonal Antibody in HIV-infected Adults
David Ho
NCT07390955 RECRUITING A Study of Safety and Drug Levels of ePGT121v1-LS, PGDM1400LS, and VRC07-523LS in Adult Participants Without HIV-1
National Institute of Allergy and Infectious Diseases (NIAID)
NCT05903339 ACTIVE NOT RECRUITING Clinical Trial to Evaluate the Safety and Immunogenicity of Ferritin Nanoparticles Expressing Native-like HIV-1 Envelope Trimers Followed by Boost With mRNA Lipid Nanoparticles Encoding a Native-like HIV-1 Envelope Trimer in Adults Without HIV
National Institute of Allergy and Infectious Diseases (NIAID)
NCT06310551 RECRUITING First Time in Human Study of Long Acting VH4524184 Formulations
ViiV Healthcare
NCT06819176 RECRUITING Lenacapavir Intensification to Disrupt HIV Reservoirs in Virologically Suppressed People With HIV Receiving Antiretroviral Therapy
National Institute of Allergy and Infectious Diseases (NIAID)
NCT07055451 ACTIVE NOT RECRUITING Study of Bictegravir/Emtricitabine/Tenofovir Alafenamide in Newborns Exposed to HIV
Gilead Sciences
NCT07530198 RECRUITING HIV Therapeutic DNA Vaccine (ICVAX) Phase I Clinical Trial in Hong Kong
Immuno Cure Holding (HK) Limited
NCT05077527 RECRUITING Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma
AIDS Malignancy Consortium
NCT06665646 RECRUITING Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Adult Participants Who Previously Participated in HVTN 706
National Institute of Allergy and Infectious Diseases (NIAID)
NCT05471076 ACTIVE NOT RECRUITING Trial to Evaluate the Safety and Immunogenicity of Priming Regimens of 426c.Mod.Core-C4b and Optional Boost Regimen With HIV Trimer BG505 SOSIP.GT1.1 gp140, Both Adjuvanted With 3M-052-AF + Alum in Healthy, Adult Participants Without HIV
National Institute of Allergy and Infectious Diseases (NIAID)
NCT07525544 NOT YET RECRUITING A Study to Investigate the Safety and PK of VH4770359 in Healthy Participants
ViiV Healthcare
NCT07390474 RECRUITING Clinical Trial to Evaluate the Safety and Immunogenicity of the V2 Apex-Directed Immunogens DV201P-RNA and DV202B1-RNA in Adult Participants Without HIV
National Institute of Allergy and Infectious Diseases (NIAID)
NCT06031272 ACTIVE NOT RECRUITING Pausing Antiretroviral Treatment Under Structured Evaluation
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
NCT06987318 NOT YET RECRUITING A Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies (VRC07-523LS and PGT121.414.LS) During Analytic Treatment Interruption in Participants Living With HIV Who Initiated ART During Acute/Early HIV-1 Infection
National Institute of Allergy and Infectious Diseases (NIAID)
NCT07342491 NOT YET RECRUITING Dasatinib for HIV-1 Reservoir Reduction
National Institute of Allergy and Infectious Diseases (NIAID)
NCT07053384 ACTIVE NOT RECRUITING A Study to Investigate the Use of VH3810109 With or Without Fostemsavir (FTR) to Reduce the Size and Activity of the Viral Reservoir in People Living With HIV
ViiV Healthcare
NCT04514484 ACTIVE NOT RECRUITING Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV
National Cancer Institute (NCI)
NCT07392372 RECRUITING A Clinical Trial Investigating the Safety and Biological Activity of the Antibody BNT351 in Adults Living Without and With HIV
BioNTech SE
NCT06517693 RECRUITING Safety and Pharmacokinetics Study of PGT121.414.LS Alone and in Combination With VRC07-523LS in Infants Exposed to HIV-1
National Institute of Allergy and Infectious Diseases (NIAID)
NCT05612178 ACTIVE NOT RECRUITING A Study to Evaluate the Safety and Effects of Repeated Doses of 3BNC117-LS and 10-1074-LS on Persistent Viral Reservoirs in People Living With HIV and on Suppressive Antiretroviral Therapy
National Institute of Allergy and Infectious Diseases (NIAID)
NCT06908083 ENROLLING BY INVITATION Immunologic and Virologic Parameters During Analytical Treatment Interruption Following Combination bNAb Therapy During Suppressive ART
National Institute of Allergy and Infectious Diseases (NIAID)
NCT06652958 ACTIVE NOT RECRUITING A Study to Assess the Safety and Pharmacokinetics of a Human Monoclonal Antibody (VH4527079) in Healthy Adults and Persons With HIV
ViiV Healthcare
NCT06880380 RECRUITING The Efficacy and Safety Study of CAR-T Cells for Functional Cure in HIV-1/AIDS Patients
Institute of Hematology & Blood Diseases Hospital, China
NCT07443228 NOT YET RECRUITING Recombinant Human Interleukin-7 (JL18008) for the Treatment of HIV-Infected Immunological Non-Responders
Jecho Biopharmaceuticals Co., Ltd.
NCT06617091 RECRUITING A Trial of a Gorilla Adenovirus Vectored Networked Epitopes Vaccine, Administered to Healthy Adults Living Without and With HIV.
International AIDS Vaccine Initiative
NCT07349758 RECRUITING Evaluation of Single Dosing With Two F/TAF Tablets Among Healthy Volunteers
Johns Hopkins University
NCT07181486 RECRUITING Safety Study of MucoCept-CVN
Craig Cohen, MD, MPH
NCT06513819 RECRUITING HIV and Alcohol Research Center Focused on Polypharmacy (HARP) Pilot 2 (2nd HARP Pilot Intervention)
Yale University
NCT06006546 ACTIVE NOT RECRUITING The Study of Immunization in People Living With HIV Undergoing an ATI for Elicitation of VRC01-lineage Antibodies
National Institute of Allergy and Infectious Diseases (NIAID)
NCT06557785 ACTIVE NOT RECRUITING A Clinical Trial to Evaluate the Safety and Immunogenicity of CH505M5 N197D mRNA-gp160 Followed by CH505 TF mRNA-gp160 in Adults in Overall Good Health Without HIV
National Institute of Allergy and Infectious Diseases (NIAID)
NCT05418868 RECRUITING A Study to Investigate Pharmacokinetics, Safety and Tolerability of Long-Acting Cabotegravir Plus Recombinant Human Hyaluronidase PH20 in Healthy Adult Participants
ViiV Healthcare
NCT06919016 ACTIVE NOT RECRUITING A Study to Evaluate the Safety and Immunogenicity of the V3-region Directed Immunogens DV700P-RNA Followed by DV701B1.1-RNA in Adults Without HIV
National Institute of Allergy and Infectious Diseases (NIAID)
NCT07279129 NOT YET RECRUITING Decision Support Tool to Integrate PrEP Into Emergency Departments
George Washington University
NCT07217379 RECRUITING The DART DELIVER-02 Study
University of North Carolina, Chapel Hill
NCT06613789 NOT YET RECRUITING Safety & Immunogenicity of 426c.Mod.Core-C4b Vaccine With 3M-052-AF+Alum in Infants Perinatally Exposed to HIV But Uninfected
HIV Vaccine Trials Network
NCT05069688 RECRUITING Dolutegravir Pharmacokinetics Among HIV/TB Coinfected Children Receiving Standard and High-dose Rifampicin
Brigham and Women's Hospital
NCT06970223 ACTIVE NOT RECRUITING A Study to Investigate if Long Acting Cabotegravir (CAB) and Lenacapavir (LEN) Injections Are Tolerable and Acceptable When Administered to Healthy Adults Without HIV
ViiV Healthcare
NCT01961063 ACTIVE NOT RECRUITING Gene Therapy After Frontline Chemotherapy in Treating Patients With AIDS-Related Non-Hodgkin Lymphoma
City of Hope Medical Center
NCT02337985 ACTIVE NOT RECRUITING Gene Therapy and Combination Chemotherapy in Treating Patients With AIDS-Related Non-Hodgkin Lymphoma
City of Hope Medical Center
NCT06034314 ACTIVE NOT RECRUITING Oral Dronabinol-HIV
Yale University
NCT06724640 RECRUITING A Study to Assess the Safety, Tolerability, and Pharmacokinetics of VH4011499 Compared to Placebo in Adults Without HIV
ViiV Healthcare
NCT05217641 ACTIVE NOT RECRUITING A Clinical Trial to Evaluate the Safety and Immunogenicity of BG505 MD39.3, BG505 MD39.3 gp151, and BG505 MD39.3 gp151 CD4KO HIV Trimer mRNA Vaccines in Healthy, HIV-uninfected Adult Participants
National Institute of Allergy and Infectious Diseases (NIAID)
NCT02500849 ACTIVE NOT RECRUITING Safety Study of Zinc Finger Nuclease CCR5-modified Hematopoietic Stem/Progenitor Cells in HIV-1 Infected Patients
City of Hope Medical Center
NCT06205056 RECRUITING Evaluation of Safety and Immunogenicity of Ad26.Mos4.HIV and CH505 TF chTrimer Combination in Healthy Adults
U.S. Army Medical Research and Development Command
NCT06796686 RECRUITING Clinical Trial to Evaluate the Safety and Immunogenicity of a Priming Regimen of 426c.Mod.Core-C4b Followed by HxB2.WT.Core-C4b Boosts, Both Adjuvanted With 3M-052 AF + Alum, in Adult Participants Without HIV and in Overall Good Health
National Institute of Allergy and Infectious Diseases (NIAID)
NCT06484335 RECRUITING RV630 - Approach to Control HIV With Immune Enhancement and Vaccination (ACHIEV
Henry M. Jackson Foundation for the Advancement of Military Medicine
NCT03617198 ACTIVE NOT RECRUITING CD4 CAR+ ZFN-modified T Cells in HIV Therapy
University of Pennsylvania
NCT06012136 ACTIVE NOT RECRUITING A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of a Single Suspension Injection of Investigational Capsid Inhibitors Compared to Placebo in Healthy Adults
ViiV Healthcare
NCT06786520 ACTIVE NOT RECRUITING A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Cabotegravir Ultra Long-acting (CAB ULA) Following Switch From Cabotegravir Long-acting (CAB LA) in Healthy Adults
ViiV Healthcare
NCT03729752 RECRUITING PET Imaging of Radiolabeled Anti-HIV-1 Envelope Monoclonal Antibody (VRC01)
University of California, San Francisco
NCT04248192 ACTIVE NOT RECRUITING Evaluate the Safety, Immunologic, and Virologic Responses of Donor Derived (DD) HIV-Specific T-cells (HST) in HIV-infected Individuals Following Allogeneic Bone Marrow Transplantation (alloRESIST)
Catherine Bollard
NCT03374202 ACTIVE NOT RECRUITING Safety and Tolerability of AAV8 Delivery of a Broadly Neutralizing Antibody in Adults Living With HIV: a Phase 1, Dose-escalation Trial
National Institute of Allergy and Infectious Diseases (NIAID)
NCT04340596 ACTIVE NOT RECRUITING Safety, Tolerability, and Efficacy of IL-15 Superagonist (N-803) With and Without Combination Broadly Neutralizing Antibodies to Induce HIV-1 Control During Analytic Treatment Interruption
National Institute of Allergy and Infectious Diseases (NIAID)
NCT06281834 RECRUITING Dolutegravir Pharmacokinetics During Weekly Rifapentine/Isoniazid for TB Prevention
Brigham and Women's Hospital
NCT06332339 ACTIVE NOT RECRUITING Clinical Trial to Evaluate the Safety, Tolerability, and Immunogenicity of 16055 NFL Delta Gly4 Env Protein Trimer and Trimer 4571 Combined With 3M-052-AF + Alum Adjuvant and Ad4-Env145NFL Viral Particles as Heterologous Prime-boost Regimens in Adult Participants Without HIV.
National Institute of Allergy and Infectious Diseases (NIAID)
NCT05983874 ENROLLING BY INVITATION A Study to Evaluate the Safety and Immunogenicity of 2 Doses of 100µg BG505 SOSIP.664 gp140 Vaccine, Adjuvanted, Given to a Population of Adults Who Have Received 3 Doses of 300µg BG505 SOSIP.GT1.1 gp140 Vaccine, Adjuvanted
International AIDS Vaccine Initiative
NCT05143307 ENROLLING BY INVITATION Long-Term Follow-Up Study of HIV-1 Infected Adults Who Received EBT-101
Excision BioTherapeutics
NCT03240328 RECRUITING The Effect of Chimeric Antigen Receptor (CAR)-T Cell Therapy on the Reconstitution of HIV-specific Immune Function
Guangzhou 8th People's Hospital
NCT07596888 NOT YET RECRUITING IAP-086-1: A Phase 1 Single Ascending Dose First-Time in Human Study
University of North Carolina, Chapel Hill
NCT05349968 COMPLETED Pharmacokinetics and Efficacy of Multiple Dosing of Lipovirtide for Injection in HIV-infected Patients
Shanxi Kangbao Biological Product Co., Ltd.
NCT07001319 COMPLETED Study of GS-3242 in Participants With HIV-1; Substudy-05
Gilead Sciences
NCT04592315 COMPLETED A Study to Assess the Safety, Tolerability and Pharmacokinetics of Lipovirtide in HIV-infected Patients
Shanxi Kangbao Biological Product Co., Ltd.
NCT03220724 COMPLETED Evaluating the Safety and Immunogenicity of EnvSeq-1 and CH505 M5 gp120 Envs Adjuvanted With GLA-SE in Healthy, HIV-Uninfected Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT05470400 TERMINATED A Clinical Trial to Evaluate Safety, Tolerability, and Immunogenicity of Adjuvanted HIV-1 Fusion Peptide Conjugate Vaccine Alone or in Prime-Boost Regimens With Adjuvanted HIV-1 Envelope Trimer 4571 and HIV-1 Trimer 6931 Vaccines in Healthy Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT05933824 COMPLETED Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Immunogenicity of LP-98 Injection in Healthy Subjects
Shanxi Kangbao Biological Product Co., Ltd.
NCT06580587 COMPLETED A Study of MK-8527 in Healthy Lactating Female Participants (MK-8527-009)
Merck Sharp & Dohme LLC
NCT04900974 COMPLETED Single Dose Pharmacokinetics of Doravirine in HIV-infected Pregnant Women
University of North Carolina, Chapel Hill
NCT04915768 COMPLETED Evaluating the Safety and Immunogenicity of Stabilized CH505 TF chTrimer in Healthy, HIV-uninfected Adult Participants.
National Institute of Allergy and Infectious Diseases (NIAID)
NCT04760691 COMPLETED Pre-Exposure Prophylaxis (PrEP)- Gender Affirming Hormone Therapy (GAHT) Interactions in TGW
Johns Hopkins University
NCT05245292 COMPLETED 3BNC117-LS and 10-1074-LS Plus N-803 (bNAb+N-803)
Rockefeller University
NCT06033209 COMPLETED A Trial to Evaluate an HIV Envelope Trimer, N332-GT5 gp140, Adjuvanted With SMNP in Adult Participants Without HIV
National Institute of Allergy and Infectious Diseases (NIAID)
NCT06585891 COMPLETED Study of a Human Bispecific Antibody VRC-HIVMAB0121-00-AB (CAP256J3LS) Administered Intravenously or Subcutaneously to Healthy Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT06253533 COMPLETED ICVAX as a HIV Therapeutic DNA Vaccine
Immuno Cure Holding (HK) Limited
NCT07066722 COMPLETED A Study to Evaluate VH4524184 Tablet Absorption, Effects of Food, and Interactions With Other Drugs in Healthy Adults
ViiV Healthcare
NCT05854381 COMPLETED To Investigate Safety, Reactogenicity and Immunogenicity of VIR-1388 Compared With Placebo in Participants Without HIV
National Institute of Allergy and Infectious Diseases (NIAID)
NCT06680479 SUSPENDED Safety and Immunogenicity of Stabilized CH505 TF chTrimer Vaccination in Adults Living With HIV-1 on Suppressive Antiretroviral Therapy
National Institute of Allergy and Infectious Diseases (NIAID)
NCT04920539 COMPLETED In Vivo Study of THC-induced Immune-genome Changes at Single Cell Solution in HIV-infected Humans
Yale University
NCT05423418 COMPLETED Safety, Tolerability, and Immunogenicity of ALFQ in a HIV Vaccine Containing A244 and B.65321 in Healthy Adults
U.S. Army Medical Research and Development Command
NCT06033547 COMPLETED A Study to Investigate the Pharmacokinetics, Safety, and Tolerability of Two Different Formulations of Long-acting Cabotegravir in Healthy Adult Participants
ViiV Healthcare
NCT04607408 COMPLETED Evaluating Safety and Immune Response to the HIV-1 CH505 Transmitted/Founder gp120 Adjuvanted With GLA-SE in Healthy, HIV-exposed Uninfected Infants
HIV Vaccine Trials Network
NCT05230368 COMPLETED Evaluation of the Safety and the Tolerability of a Combination of Two HIV Inducers in Patients With Undetectable Viral Load
ANRS, Emerging Infectious Diseases
NCT04985760 COMPLETED Evaluation of Trimer 4571 Therapeutic Vaccination in Adults Living With HIV on Suppressive Antiretroviral Therapy
Madhu Chhanda Choudhary
NCT02408861 TERMINATED Nivolumab and Ipilimumab in Treating Patients With HIV Associated Relapsed or Refractory Classical Hodgkin Lymphoma or Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery
National Cancer Institute (NCI)
NCT05631704 COMPLETED A Study to Investigate Safety, Tolerability, and Pharmacokinetics (PK) of VH4524184 and the Potential for Changes in Cytochrome P450 3A (CYP3A) Activity
ViiV Healthcare
NCT05182125 COMPLETED Phase 1 Clinical Trial to Evaluate the Safety and Immunogenicity of HIV-1 Chimp Adenovirus Vaccines Expressing Clade C gp140 & CH505TF gp120 Protein Boost in HIV-uninfected Adult.
HIV Vaccine Trials Network
NCT02591420 COMPLETED Safety and Virologic Effect of a Human Monoclonal Antibody (VRC01) Administered Intravenously to Adults During Early Acute HIV Infection
National Institute of Allergy and Infectious Diseases (NIAID)
NCT06430905 TERMINATED Safety, Reactogenicity and Immunogenicity of HB-502 and HB-501 Versus Placebo in People With HIV on Suppressive ART
Hookipa Biotech GmbH
NCT05781542 COMPLETED Clinical Trial to Evaluate the Safety and Immunogenicity of Synthetic DNAs Encoding NP-GT8 and IL-12, With or Without a TLR-agonist-Adjuvanted HIV Env Trimer 4571 Boost, in Adults Without HIV
National Institute of Allergy and Infectious Diseases (NIAID)
NCT03670355 COMPLETED Pharmacokinetic and Safety Study of a 90 Day Intravaginal Ring Containing Tenofovir
National Institute of Allergy and Infectious Diseases (NIAID)
NCT03758625 COMPLETED Comparison of Dendritic Cell-Based Therapeutic Vaccine Strategies for HIV Functional Cure
Sharon Riddler
NCT07115368 TERMINATED Study of GS-1219 in Participants With HIV-1
Gilead Sciences
NCT03239899 COMPLETED PD-1 Inhibition to Determine CNS Reservoir of HIV-Infection
National Institute of Neurological Disorders and Stroke (NINDS)
NCT03526848 COMPLETED 3BNC117 and 10-1074 in ART-treated Individuals
Rockefeller University
NCT03934541 COMPLETED Evaluating the Safety and Immunogenicity of an HIV-1 gp41 MPER-656 Liposome Vaccine in Healthy, HIV-uninfected Adult Participants
National Institute of Allergy and Infectious Diseases (NIAID)
NCT06905275 SUSPENDED A Clinical Trial to Evaluate the Safety and Immunogenicity of Glycan-trimmed HIV-1 Nanoparticle Vaccine (UVAX-1107), Followed by Homologous or Wild-type HIV-1 Nanoparticle Vaccine (UVAX-1197) Boost, Each Adjuvanted With 3M-052-AF + Alum in Adult Participants Without HIV
National Institute of Allergy and Infectious Diseases (NIAID)
NCT04177355 COMPLETED Evaluating the Safety and Immunogenicity of HIV-1 BG505 SOSIP.664 gp140 With TLR Agonist and/or Alum Adjuvants in Healthy, HIV-uninfected Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT05828095 COMPLETED A Clinical Trial to Evaluate the Safety and Immunogenicity of Synthetic DNAs Encoding a Native-like HIV Env Trimer and Interleukin-12 (INO-6160), Alone or in a Prime-boost Regimen With 3M-052-AF + Alum Adjuvanted VRC HIV Env Trimer 4571 in Adult Participants Without HIV
National Institute of Allergy and Infectious Diseases (NIAID)
NCT05406583 COMPLETED A Study of the Safety, Tolerability, and Pharmacokinetics of Dolutegravir in Neonates Exposed to HIV-1
National Institute of Allergy and Infectious Diseases (NIAID)
NCT05604209 COMPLETED Safety and Immunogenicity of HIV-1 Vaccines C62-M4 or C1C62-M3M4 in Persons With HIV-1 Suppressed on ART
University of North Carolina, Chapel Hill
NCT05627258 COMPLETED A Study of the Safety and Pharmacokinetics of a Human Monoclonal Antibody, VRCHIVMAB0115-00-AB (VRC01.23LS), Administered Intravenously or Subcutaneously to Healthy Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT02413645 COMPLETED Phase I, Open Label Dose Escalation Study to Evaluate Safety of iHIVARNA-01 in Chronically HIV-infected Patients
Judit Pich Martínez
NCT04301154 COMPLETED Safety and Effects of Using Prime-boost HIVIS DNA and MVA-CMDR Vaccine Regimens With or Without Toll-like Receptor 4 Agonist on HIV Reservoirs in Perinatally HIV Infected Children and Youth
Henry M. Jackson Foundation for the Advancement of Military Medicine
NCT04658667 COMPLETED HIV Vaccine in HIV-uninfected Adults
U.S. Army Medical Research and Development Command
NCT05163522 COMPLETED First-Time-in-Human (FTIH) Study to Evaluate the Safety, Tolerability and Pharmacokinetics (PK) of VH4004280 in Healthy Participants
ViiV Healthcare
NCT01152255 TERMINATED MK6186 in HIV-1 Infected Patients (MK-6186-007 AM2)
Merck Sharp & Dohme LLC
NCT04515641 COMPLETED Single-Dose Islatravir in Moderate Hepatic Impairment (MK-8591-030)
Merck Sharp & Dohme LLC
NCT04493684 COMPLETED GSK3739937 First-Time-In-Human (FTIH) Study in Healthy Volunteers
ViiV Healthcare
NCT05869864 COMPLETED Schools Championing Safe South Africa
Brown University
NCT03735849 COMPLETED Evaluating the Safety and Pharmacokinetics of VRC07-523LS in the Sera and Mucosae of Healthy, HIV-Uninfected Adult Participants
National Institute of Allergy and Infectious Diseases (NIAID)
NCT05585307 COMPLETED Study of Novel Antiretrovirals in Participants With HIV-1
Gilead Sciences
NCT03485963 COMPLETED HIV-1 Specific T -Cells (HST-NEETs) for HIV-Infected Individuals
Catherine Bollard
NCT04586673 COMPLETED A Study to Assess Safety and Immunogenicity of Conserved Mosaic HIV-1 Vaccines
University of Oxford
NCT06533280 WITHDRAWN VH3739937 Phase 1 Multiple Ascending Dose (MAD) Study in Healthy Volunteers Including Relative Bioavailability (RBA), Optional Food Effect (FE), and Drug-drug Interaction (DDI)
ViiV Healthcare
NCT05393271 COMPLETED First-Time-in-Human (FTIH) Study to Evaluate the Safety, Tolerability and Pharmacokinetics (PK) of VH4011499 in Healthy Participants
ViiV Healthcare
NCT05261191 COMPLETED A Study of MGD020 Alone or Combined With MGD014 in Persons With HIV-1 on Antiretroviral Therapy
MacroGenics
NCT04826094 COMPLETED A Study to Assess the Safety and Immune Response to Env-C DNA and Protein Vaccines in Kenya
National Institute of Allergy and Infectious Diseases (NIAID)
NCT06267872 WITHDRAWN A Clinical Trial in Adult Participants Without HIV and in Overall Good Health to Evaluate the Safety and Immunogenicity of CD4BS CH505M5 Pr-NP1 Followed by CH505 TF chTrimer Boost Both Adjuvanted With Either Lipid Nanoparticles (LNPs) or 3M-052-AF + Alum
National Institute of Allergy and Infectious Diseases (NIAID)
NCT04283656 COMPLETED Evaluating Drug Interactions Between Doravirine With Estradiol and Spironolactone in Healthy Transgender Women
Thomas Jefferson University
NCT05494736 COMPLETED MK-8527 Single-Dose Trial in HIV-1 Infected Participants (MK-8527-004)
Merck Sharp & Dohme LLC
NCT01276600 COMPLETED Dose-Proportionality and Intra-Individual Variability of Intracellular TFV-DP and FTC-TP in Healthy Volunteers
HIV Prevention Trials Network
NCT03157167 COMPLETED An Evaluation of Tc 99m Tilmanocept by Intravenous (IV) and Subcutaneous (SC) Injection in Kaposi Sarcoma (KS)
Navidea Biopharmaceuticals
NCT06368986 COMPLETED A Study to Investigate the Effect of Food on the Bioavailability of a Capsid Inhibitor (CAI) in Male and Female Healthy Participants
ViiV Healthcare
NCT05184452 COMPLETED A Clinical Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of PGDM1400LS Alone and in Combination With VRC07-523LS and PGT121.414.LS in Healthy, HIV-uninfected Adult Participants
National Institute of Allergy and Infectious Diseases (NIAID)
NCT03307915 COMPLETED A Study of 2 Different Regimens of Tetravalent Ad26.Mos4.HIV Prime Followed by Boost With Modified Vaccinia Ankara (MVA)-Mosaic OR Ad26.Mos4.HIV Plus a Combination of Mosaic and Clade C gp140 Protein in Human Immunodeficiency Virus (HIV) Type 1 Infected Adults on Suppressive Antiretroviral Treatment
Janssen Vaccines & Prevention B.V.
NCT02589795 COMPLETED Safety and Immunogenicity of HIV DNA-C CN54ENV and Recombinant HIV CN54gp140 Vaccines in Healthy Volunteers
Imperial College London
NCT02840474 COMPLETED Phase 1, Open-label, Single Dose Study to Examine Safety, Tolerability, Pharmacokinetics and Virologic Impact of VRC01LS or VRC07-523LS in HIV-infected Viremic Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT04568603 COMPLETED Islatravir and Methadone Pharmacokinetics (MK-8591-029)
Merck Sharp & Dohme LLC
NCT04811040 COMPLETED Study to Evaluate the Safety and Efficacy of Teropavimab and Zinlirvimab in Combination With Lenacapavir in Virologically Suppressed Adults With HIV-1 Infection
Gilead Sciences
NCT06783192 COMPLETED A Drug-Drug Interaction Study of MK 8527 With a Combined Oral Contraceptive (LNG/EE)
Merck Sharp & Dohme LLC
NCT03367754 TERMINATED A Single Dose of Pembrolizumab in HIV-Infected People
National Institute of Allergy and Infectious Diseases (NIAID)
NCT01497405 COMPLETED WHC+ (Women's Health CoOp PLUS)
RTI International
NCT04212091 COMPLETED Evaluating the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of the Monoclonal Antibody PGT121.414.LS Administered Alone and in Combination With VRC07-523LS Via Intravenous or Subcutaneous Infusions in Healthy, HIV-uninfected Adult Participants
National Institute of Allergy and Infectious Diseases (NIAID)
NCT05850728 COMPLETED First in Human Study of TLC-ART 101 (ACTU 2001)
University of Washington
NCT06310616 COMPLETED A Study to Investigate the Potential Drug-Drug Interaction Between VH4524184 and Oral Contraceptive (Loestrin) in Healthy Adult Female Participants
ViiV Healthcare
NCT04950530 COMPLETED The Effect of Biktarvy (B/F/TAF) on Whole-body Insulin Sensitivity, Lipid and Endocrine Profile in Healthy Volunteers
Chelsea and Westminster NHS Foundation Trust
NCT04224701 COMPLETED A Clinical Trial to Evaluate the Safety and Immunogenicity of Recombinant HIV-1 Envelope Protein BG505 SOSIP.GT1.1 Gp140 Vaccine, Adjuvanted in Healthy, HIV-uninfected Adults
International AIDS Vaccine Initiative
NCT05458102 TERMINATED Drug-Drug Interaction Study of Vesatolimod in Adults With HIV-1 Who Have Very Low or Undetectable Virus Levels
Gilead Sciences
NCT05144386 COMPLETED Study of EBT-101 in Aviremic HIV-1 Infected Adults on Stable ART
Excision BioTherapeutics
NCT04058392 COMPLETED Camu Camu in ART-treated People Living with HIV
McGill University Health Centre/Research Institute of the McGill University Health Centre
NCT00798265 TERMINATED A Phase I Study of Quadrivalent Human Papilloma Virus (HPV) (Types 6, 11, 16, 18) Recombinant Vaccine in HIV-Infected and HIV-Negative Pre-Adolescents, Adolescents, and Young Adults
National Cancer Institute (NCI)
NCT03816137 COMPLETED Modelling the Interaction Between Rationally-designed Synthetic Model Viral Protein Immunogens
Imperial College London
NCT03408262 COMPLETED Clinical Trial of HIV Vaccine Combinations in Healthy Men and Women
Imperial College London
NCT04833127 COMPLETED A Gender-Enhanced Pre-Exposure Prophylaxis (PrEP) Information-Motivational Workshop for Young South African Women
New York State Psychiatric Institute
NCT03894124 COMPLETED Pharmacokinetics of Plasma Doravirine Once Daily Over 72 Hours Following Drug Intake Cessation in Healthy Volunteers
Chelsea and Westminster NHS Foundation Trust
NCT05291520 COMPLETED A Study to Investigate the Safety and Pharmacokinetics of a Single Dose of VH3810109 (Also Known as GSK3810109), Administered Either Subcutaneously (SC) With rHuPH20 or Intravenously (IV), in Healthy Adult Participants
ViiV Healthcare
NCT04630002 COMPLETED Drug-drug Interaction (DDI) Study of GSK3640254 With Darunavir/Ritonavir (DRV/RTV) and Etravirine (ETR)
ViiV Healthcare
NCT05362955 COMPLETED 5-fluorouracil Following Cervical Intraepithelial Neoplasia Treatment Among HIV-positive Women in East Africa
UNC Lineberger Comprehensive Cancer Center
NCT02595866 COMPLETED Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer
National Cancer Institute (NCI)
NCT06168318 COMPLETED A Study to Investigate the Relative Bioavailability and Food Effect of an Oral Capsid Inhibitor Tablet Formulation Compared With Other Oral Tablet Formulations in Male and Female Healthy Participants
ViiV Healthcare
NCT03856996 COMPLETED A Clinical Trial in Healthy, HIV-1-Uninfected Adult Participants to Compare the Safety, Tolerability and Immunogenicity of CH505TF gp120 Produced From Stably Transfected Cells to CH505TF gp120 Produced From Transiently Transfected Cells
National Institute of Allergy and Infectious Diseases (NIAID)
NCT05959707 SUSPENDED Evaluating the Safety, Tolerability, and Pharmacokinetics of Monoclonal Antibodies in Healthy Participants
HIV Vaccine Trials Network
NCT05416021 COMPLETED Relative Bioavailability Trial of Dapivirine Ring-004 and Ring-008
International Partnership for Microbicides, Inc.
NCT04893018 TERMINATED NT-I7 for Kaposi Sarcoma in Patients With or Without HIV
Fred Hutchinson Cancer Center
NCT03960645 COMPLETED Study to Evaluate the Pharmacokinetics (PK), Safety, and Efficacy of B/F/TAF in Human Immunodeficiency Virus (HIV)-1 Infected, Virologically Suppressed, Pregnant Women in Their Second and Third Trimesters
Gilead Sciences
NCT06450275 COMPLETED Bioequivalence Study to Compare Dolutegravir 50mg Film-coated Tablets
Humanis Saglık Anonim Sirketi
NCT01712425 COMPLETED Safety and Immunogenicity of ChAdV63.HIVconsv and MVA.HIVconsv Candidate HIV-1 Vaccines in Recently HIV-1 Infected Individuals
IrsiCaixa
NCT05208125 COMPLETED A Phase I, Randomized, Double-Blind, Placebo-Controlled Safety, Tolerability and Immunogenicity Study of Candidate HIV-1 Vaccines ChAdOx1.HTI and MVA.HTI With Recombinant HIV-1 Envelope Protein ConM SOSIP.v7 gp140 Vaccine, Adjuvanted With MPLA Liposomes in ART-Suppressed HIV-1 Positive Individuals
IrsiCaixa
NCT02616874 COMPLETED Study to Evaluate the Safety and Effect of HIVconsv Vaccines in Combination With Histone Deacetylase Inhibitor Romidepsin on the Viral Rebound Kinetic After Treatment Interruption in Early Treated HIV-1 Infected Individuals
IrsiCaixa
NCT05769569 WITHDRAWN Safety and Efficacy of Neutralizing Antibodies and Vaccination for Induction of HIV Remission
Henry M. Jackson Foundation for the Advancement of Military Medicine
NCT05944848 COMPLETED A Study of CL-197 Capsules in Healthy Participants
Henan Genuine Biotech Co., Ltd.
NCT04371380 COMPLETED Pharmacokinetic Study of Cabotegravir and Rilpivirine Long-acting Intramuscular Injections in Healthy Adult Participants
ViiV Healthcare
NCT02531295 TERMINATED Immunologic Response to Kansui in Treated HIV+ Individuals: a Dose Escalation Study
University of California, San Francisco
NCT04927585 COMPLETED Evaluating the Safety and Immunogenicity of Polyvalent DNA/gp120 HIV Vaccine in Healthy, HIV-uninfected Adults
Worcester HIV Vaccine
NCT04808908 COMPLETED Effect of N-803 on B Cell Follicles in Antiretroviral Treated HIV Disease
University of Minnesota
NCT02797171 COMPLETED Evaluating the Safety, Pharmacokinetics, and Anti-Viral Activity of VRC01 and VRC01LS in the Serum and Mucosa of Healthy, HIV-Uninfected Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT02771730 TERMINATED Study to Evaluate the Safety and Immunogenicity of an Oral HIV Vaccine in Healthy, HIV-uninfected Adults
Emergent BioSolutions
NCT04857892 COMPLETED A Relative Bioavailability and Food-Effect Study of the Fixed Dose Combination of GSK3640254 and Dolutegravir (DTG) in Healthy Participants
ViiV Healthcare
NCT04554966 COMPLETED Study to Assess Adverse Events and How Intravenous (IV) or Subcutaneous (SC) ABBV-382 Moves Through the Body of Adult Participants With Human Immuno-Deficiency Virus (HIV-1)
AbbVie
NCT05700630 WITHDRAWN Ph1 Study of FT538 Alone and With Vorinostat for Persistent Low-Level HIV Viremia
Masonic Cancer Center, University of Minnesota
NCT02750540 COMPLETED Optimization of a Tenofovir Enema for HIV Prevention
Johns Hopkins University
NCT03181789 COMPLETED Safety and Immunogenicity of pDNA Vaccines Expressing HIV M Group p24^Gag Conserved Elements and/or p55^Gag, Administered With IL-12 pDNA
National Institute of Allergy and Infectious Diseases (NIAID)
NCT03538626 COMPLETED Phase I, Open-Label, Dose-Escalation Study of a Human Monoclonal Antibody, VRC-HIVMAB091-00-AB (N6LS), Administered Intravenously or Subcutaneously With or Without Recombinant Human Hyaluronidase PH20 (rHuPH20)
National Institute of Allergy and Infectious Diseases (NIAID)
NCT03705169 TERMINATED Pharmacokinetics and Safety of SAR441236
National Institute of Allergy and Infectious Diseases (NIAID)
NCT04408963 COMPLETED A Phase 1 Trial to Evaluate CAP256V2LS in Healthy Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT04425902 COMPLETED Evaluation of Pharmacokinetic Interaction Between GSK3640254 and Caffeine, Metoprolol, Montelukast, Flurbiprofen, Omeprazole, Midazolam, Digoxin, and Pravastatin in Healthy Adults
ViiV Healthcare
NCT04047420 COMPLETED Safety and Pharmacokinetic Study of Tenofovir Alafenamide (TAF)/Elvitegravir (EVG) Administered Rectally
National Institute of Allergy and Infectious Diseases (NIAID)
NCT03699241 COMPLETED A Randomized, Double-blinded, Placebo-controlled, Dose-escalation Phase 1 Clinical Trial to Evaluate the Safety and Immunogenicity of Recombinant HIV Envelope Protein BG505 SOSIP.664 gp140 Vaccine, Adjuvanted, in Healthy, HIV-1 Uninfected Adults
International AIDS Vaccine Initiative
NCT05776108 COMPLETED A Study to Assess the Food Effect and the Relative Bioavailability of the Cabotegravir (CAB) Pediatric Dispersible Tablet (DT) Formulation
ViiV Healthcare
NCT05489406 COMPLETED Relative Bioavailability Study to Investigate a Potential Interaction Between DTG DT and F/TAF TOS.
Radboud University Medical Center
NCT04563845 COMPLETED Effect of Therapeutic and Supratherapeutic Oral Doses of GSK3640254 on Cardiac Conduction Compared to Placebo and a Single Oral Dose of Moxifloxacin
ViiV Healthcare
NCT04484337 COMPLETED Study to Evaluate Pharmacokinetic (PK), Safety and Tolerability of Cabotegravir (CAB) 400 Milligrams Per Milliliter (mg/mL) Formulation in Healthy Adult Participants
ViiV Healthcare
NCT02579083 COMPLETED Safety Study of Monoclonal Antibodies to Reduce the Vaginal Transmission of HSV and HIV
KBio Inc
NCT01671982 COMPLETED ALternative TEnofovir Dosing in Adults With Moderate Renal Function Impairment
Institut de Recherche pour le Developpement
NCT04686279 COMPLETED Tenofovir Rectal Douche to Prevent HIV Transmission Among Adolescents (ATN DREAM)
University of Pennsylvania
NCT03270969 COMPLETED A Pharmacokinetic Evaluation of Tenofovir/Emtricitabine as HIV Pre-Exposure Prophylaxis in Transgender Women
University of Nebraska
NCT05197075 COMPLETED A Study to Assess the Acceptability of the Darunavir/Cobicistat (DRV/COBI) Fixed-dose Combination (FDC) Tablet in Human Immunodeficiency Virus (HIV)-1 Infected Children
Janssen Research & Development, LLC
NCT05079451 WITHDRAWN Broadly Neutralizing Antibodies 3BNC117-LS & 10-1074-LS to Prevent Relapse During ATI
National Institute of Allergy and Infectious Diseases (NIAID)
NCT04032717 TERMINATED Griffithsin-based Rectal Microbicide for PREvention of Viral ENTry (PREVENT)
Rhonda Brand
NCT04250636 COMPLETED 3BNC117-LS and 10-1074-LS in Viremic HIV-infected Individuals
Rockefeller University
NCT04827134 COMPLETED A Food-effect Study of the Pediatric Dispersible Tablet Formulations of TRIUMEQ® and DOVATO® in Healthy Adult Participants
ViiV Healthcare
NCT01433289 COMPLETED Study to Evaluate Safety and Toxicity of Polyphenon E (EGCG) in HIV-1-Infected Individuals
Baylor College of Medicine
NCT03212989 COMPLETED Study to Evaluate Effects of Vorinostat and HXTC on Persistent HIV-1 Infection in HIV-Infected Subjects Started on Antiretroviral Therapy (ART)
University of North Carolina, Chapel Hill
NCT02296541 COMPLETED Evaluating the Safety and Immune Response to Three Different DNA HIV Vaccines Administered With a MVA-CMDR Boost Vaccine in Healthy, HIV-Uninfected Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT04620304 COMPLETED Study for Evaluation of the Safety, Pharmacokinetics, and Antiviral Activity of UB-421 Subcutaneous Formulation Administered in HIV-1 Infected Treatment Naive Patients
United BioPharma
NCT03961438 COMPLETED Amsterdam UMC Clinical Trial With a Native-like HIV-1 Envelope Vaccine
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
NCT03408899 COMPLETED Evaluating the Safety and Pharmacokinetics of PC-1005 Administered Rectally to HIV-1 Seronegative Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT03917420 COMPLETED Quantification of Estradiol's Impact on Nucleotides in Cellular Populations of the Lower GI Tract
University of North Carolina, Chapel Hill
NCT04561258 COMPLETED Study to Evaluate the Safety of a Gene and Cell Therapy Product in Participants With HIV That is Well-Controlled on Antiretroviral Therapy
American Gene Technologies International Inc.
NCT02174159 COMPLETED Evaluation of Safety, Tolerability, Pharmacokinetics, and Antiretroviral Activity of Ulonivirine (MK-8507) in Human Immunodeficiency Virus (HIV-1)-Infected Participants (MK-8507-003)
Merck Sharp & Dohme LLC
NCT03387150 COMPLETED Evaluating the Safety and Serum Concentrations of a Human Monoclonal Antibody, VRC-HIVMAB075-00-AB (VRC07-523LS), Administered in Multiple Doses and Routes to Healthy, HIV-uninfected Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT01481428 COMPLETED Reducing High Risk Behavior in Treatment Court
Treatment Research Institute
NCT05700734 WITHDRAWN MK-8510 Monotherapy for the Treatment of Anti-retroviral naïve Human Immunodeficiency Virus Type 1 (HIV-1) Infected Participants (MK-8510-002)
Merck Sharp & Dohme LLC
NCT03581305 COMPLETED PET Imaging of the Dopaminergic and Serotonergic Systems in Treated HIV Positive Subjects
National Institutes of Health Clinical Center (CC)
NCT02659306 COMPLETED Metformin Immunotherapy in HIV Infection
McGill University Health Centre/Research Institute of the McGill University Health Centre
NCT04223804 COMPLETED A Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of ABBV-181 (Budigalimab) in Adult Participants With Human Immunodeficiency Virus (HIV)-1
AbbVie
NCT03875209 COMPLETED 10E8.4/iMab Bispecific Antibody in HIV-uninfected and HIV-infected Adults
David Ho
NCT04725877 COMPLETED VIR-1111: A Prototype Human CMV-based Vaccine for Human Immunodeficiency Virus (HIV) in Healthy Volunteers
Vir Biotechnology, Inc.
NCT05165550 COMPLETED Study of Single Ascending Doses of Elsulfavirine to Evaluate the Safety, Tolerability, and Pharmacokinetics of Elsulfavirine and Its Active Metabolite VM-1500A in Healthy Subjects
Viriom
NCT04672083 COMPLETED A Clinical Study of the HIV Drug CPT31 in Healthy Volunteers
Navigen, Inc.
NCT05244473 WITHDRAWN A Safety Study of Brentuximab Vedotin in Participants With HIV
Seagen Inc.
NCT02256631 COMPLETED Evaluating the Safety and Pharmacokinetics of VRC01, VRC01LS, and VRC07-523LS, Potent Anti-HIV Neutralizing Monoclonal Antibodies, in HIV-1-Exposed Infants
National Institute of Allergy and Infectious Diseases (NIAID)
NCT04195776 COMPLETED Evaluating Distribution of a Tenofovir Douche With Tap Water Douching and Simulated Receptive Anal Intercourse
Johns Hopkins University
NCT01822522 COMPLETED Cabozantinib S-Malate in Treating Patients With Advanced Solid Tumors and Human Immunodeficiency Virus
National Cancer Institute (NCI)
NCT05206019 COMPLETED Study to Evaluate Pharmacokinetic and Safety of Albuvirtide Between Intravenous Drip and Intravenous Injection
Frontier Biotechnologies Inc.
NCT02086630 COMPLETED Timely Initiation of HIV Antiretroviral Therapy Among Those Who Delay/Decline
New York University
NCT04799353 COMPLETED Study to Evaluate the Safety and How the Body Handles a Single Dose of Subcutaneous (SC) and Intravenous (IV) Budigalimab in Adult Participants Living With Human Immunodeficiency Virus (HIV)
AbbVie
NCT03570918 COMPLETED MGD014 in HIV-Infected Individuals on Suppressive Antiretroviral Therapy
MacroGenics
NCT03844386 COMPLETED Study to Assess Safety and Ability to Induce Immune Responses of HIV-1 Vaccines M3 and M4 Given Alone or in Combination in HIV-infected Adults
University of North Carolina, Chapel Hill
NCT02852005 COMPLETED Evaluating the Immunogenicity of the AIDSVAX B/E Vaccine and the MVA/HIV62B Vaccine in Healthy, HIV-1-Uninfected Adults Who Previously Received MVA/HIV62B in DNA/MVA or MVA/MVA Regimens in HVTN 205
National Institute of Allergy and Infectious Diseases (NIAID)
NCT03928821 COMPLETED Evaluating the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of Combinations of Monoclonal Antibodies PGT121, PGDM1400, 10-1074, and VRC07-523LS Administered Via Intravenous Infusion in Healthy, HIV-uninfected Adult Participants
National Institute of Allergy and Infectious Diseases (NIAID)
NCT04424264 COMPLETED The Effect of Rifampicin on the Pharmacokinetics of Intracellular Tenofovir-diphosphate and Tenofovir When Coadministered With Tenofovir Alafenamide Fumarate During the Maintenance Phase of Tuberculosis Treatment in TB/HIV-1 Coinfected Participants
Professor Francois Venter
NCT03547245 COMPLETED A Phase I Trial to Evaluate the Safety and Immunogenicity of eOD-GT8 60mer Vaccine, Adjuvanted
International AIDS Vaccine Initiative
NCT04385875 COMPLETED Study to Assess the Safety and Durability of Viral Control Beyond 24 Weeks of Analytical Treatment Interruption After the Administration of Candidate HIV-1 Vaccines DNA.HTI, MVA.HTI and ChAdOx1.HTI or Placebo in Early Treated HIV-1 Positive Individuals (ATI Extension of AELIX-002 Study)
Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia
NCT03409276 COMPLETED Evaluating the Safety and Immunogenicity of Env (A,B,C,A/E)/Gag (C) DNA and gp120 (A,B,C,A/E) Protein/GLA-SE HIV Vaccines, Given Individually or Co-administered, in Healthy, HIV-1-Uninfected Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT03834909 WITHDRAWN Pre-Exposure Prophylaxis Dosing in Pregnancy to Optimize HIV Prevention (PREP-P)
Johns Hopkins University
NCT03571204 TERMINATED Combination Therapy With 3BNC117 and 10-1074 in HIV-Infected Individuals
National Institute of Allergy and Infectious Diseases (NIAID)
NCT03618056 COMPLETED Evaluating HIV-1 Neutralization Antibody Breadth in Response to HIV gp120 Protein Vaccine in HIV-uninfected Adults With Quiescent Systemic Lupus Erythematosus
National Institute of Allergy and Infectious Diseases (NIAID)
NCT04507321 COMPLETED Pharmacokinetics and Metabolism of 14 Carbon [14C]-GSK3640254
ViiV Healthcare
NCT03709355 COMPLETED Pharmacokinetics Study to Evaluate Drug-Drug Interactions and Safety of Elpida® in Co-Administration With Other Drugs
Viriom
NCT05204121 COMPLETED Phase Ib Study of Safety, Tolerability and Pharmacokinetics of Elpida Once Weekly in Healthy Volunteers
Viriom
NCT03706898 COMPLETED Study to Evaluate the Safety and PK of Elpida® in Healthy Subjects and Patients With Hepatic Impairment and to Assess the Impact of Food Intake and Drug-Drug Interactions With Other Antiviral Drugs
Viriom
NCT02307656 COMPLETED Taste Properties of Atazanavir and Cobicistat
Bristol-Myers Squibb
NCT02778204 COMPLETED Evaluating the Safety and Pharmacokinetics of Maraviroc in HIV-1-Exposed Infants at Risk of Acquiring HIV-1 Infection
National Institute of Allergy and Infectious Diseases (NIAID)
NCT04802811 COMPLETED A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics ,Pharmacodynamics of Oral SHR2150 in Healthy Subjects
Jiangsu HengRui Medicine Co., Ltd.
NCT03837015 COMPLETED Estrogen, Probiotics and Vaginal Health to Prevent HIV Infection in ACB Women
McMaster University
NCT02756208 COMPLETED A Safety and Immunogenicity Trial of IHV01
University of Maryland, Baltimore
NCT03706911 COMPLETED Study to Evaluate Safety, Tolerability and Pharmacokinetics of VM-1500A-LAI Single and Multiple Ascending Doses in Healthy Subjects
Viriom
NCT05148754 COMPLETED An Open-label Clinical Study of the Pharmacokinetics and Safety of Elsulfavirine, 200 mg Tablets, With Single and Multiple Oral Administration in Healthy Volunteers
Viriom
NCT03803605 COMPLETED Study to Assess Safety and Activity of Combination Therapy of VRC07-523LS and Vorinostat on HIV-infected Persons
University of North Carolina, Chapel Hill
NCT02419456 COMPLETED Pharmacokinetics of Two Intravaginal Rings (IVRs) Containing Different Dose Strengths of Vicriviroc (MK-4176) and MK-2048
National Institute of Allergy and Infectious Diseases (NIAID)
NCT01780831 COMPLETED Safety and Pharmacokinetics of Raltegravir in HIV-1-Exposed Newborn Infants at Risk of Acquiring HIV-1 Infection
National Institute of Allergy and Infectious Diseases (NIAID)
NCT02028403 COMPLETED Safety and Immune Response of BMS-936559 in HIV-Infected People Taking Combination Antiretroviral Therapy
National Institute of Allergy and Infectious Diseases (NIAID)
NCT02411539 COMPLETED Evaluating the Safety, Tolerability, and Effect of a Human Monoclonal Antibody (VRC01) on Markers of HIV Persistence in HIV-Infected Adults Receiving Antiretroviral Therapy (ART)
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00695877 COMPLETED Safety and Immune Response to a Recombinant Adenovirus HIV-1 Vaccine in Healthy Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00992069 COMPLETED Safety, Tolerability, and Effect of TMC207 and Efavirenz in Healthy Volunteers
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00660972 COMPLETED Study of Viral Load Decay Rates in HIV Infected Participants Starting Treatment With Raltegravir (RAL) and Emtricitabine/Tenofovir Disoproxil Fumarate (TDF)
National Institute of Allergy and Infectious Diseases (NIAID)
NCT01260727 COMPLETED Evaluating the Safety of and Immune Response to an HIV Vaccine Followed by Booster, Administered by Two Devices, in HIV-Uninfected Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT01266616 COMPLETED Safety of and Immune Response to an Investigational HIV-1 Vaccine With or Without Interleukin-12 (IL-12) in HIV-1 Infected Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00618605 COMPLETED Safety of and Immune Response to an Adenoviral HIV-1 Vaccine in Healthy Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT04035759 COMPLETED Positive Affect Promotion to Empower Optimal Adherence to HIV Therapy
State University of New York - Downstate Medical Center
NCT00802802 COMPLETED Efavirenz (EFV) in HIV-Infected and HIV/Tuberculosis (TB) Coinfected Children
National Institute of Allergy and Infectious Diseases (NIAID)
NCT04303156 COMPLETED Pharmacokinetics of Islatravir in Participants With Severe Renal Impairment (MK-8591-026)
Merck Sharp & Dohme LLC
NCT02356302 COMPLETED Safety and Pharmacokinetics of Intravaginal Rings Containing Vicriviroc (MK-4176) and/or MK-2048
National Institute of Allergy and Infectious Diseases (NIAID)
NCT01136759 COMPLETED Tenofovir Gel in Pregnancy and Lactation
National Institute of Allergy and Infectious Diseases (NIAID)
NCT03393468 COMPLETED Pharmacokinetic Study of Dapivirine Gel Administered Rectally to HIV-1 Seronegative Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT03984812 TERMINATED Evaluation of the Safety, Tolerability and Pharmacokinetics (PK) of GSK3732394 First-Time-in-Human (FTIH) Study
ViiV Healthcare
NCT02463227 COMPLETED Evaluating the Safety, Pharmacokinetics, and Antiviral Activity of a Human Monoclonal Antibody (VRC01) in HIV-Infected Adults Undergoing a Brief Treatment Interruption
National Institute of Allergy and Infectious Diseases (NIAID)
NCT03239483 COMPLETED Safety and Pharmacokinetic Study of Dapivirine Gel (0.05%) Administered Rectally to HIV-1 Seronegative Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT01571960 COMPLETED Evaluating the Safety and Immune Response of a Prime-Boost HIV Vaccine Regimen in Healthy, HIV-Uninfected, Vaccinia-Naive Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT01438606 COMPLETED Evaluating the Safety of and Immune Response to the VSV-Indiana HIV Vaccine in Healthy, HIV-Uninfected Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT02165267 COMPLETED Evaluating the Safety and Drug Levels of an Antibody Against HIV in Healthy, HIV-Uninfected Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT03505060 WITHDRAWN Evaluating the Safety and Immunogenicity of the IHV01 Protein Vaccine Primed and Co-Administered With HIV DNA CON-S Env Vaccine in Healthy, HIV-1-Uninfected Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT02654080 COMPLETED Evaluating the Safety, Tolerability, and Immunogenicity of a Prime-Boost Regimen of HIV-1 Nef/Tat/Vif, Env pDNA Vaccine Delivered Intramuscularly With Electroporation and HIV-1 rVSV envC Vaccine in Healthy, HIV-Uninfected Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT01054872 COMPLETED Examining the Role of Genetics in Determining the Immune Response to an HIV Vaccine in HIV-Uninfected Adult Twins
National Institute of Allergy and Infectious Diseases (NIAID)
NCT01095224 COMPLETED Evaluating Heterologous-Insert Prime-Boost HIV Vaccine Regimens in HIV-Uninfected Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT02431767 COMPLETED Evaluating the Safety and Immunogenicity of PENNVAX®-GP DNA Vaccine and IL-12 Plasmid, Delivered Via Intradermal or Intramuscular Electroporation in Healthy, HIV-Uninfected Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT02207920 COMPLETED Evaluating the Safety and Immune Response to Different Combinations of the DNA-HIV-PT123 and AIDSVAX® B/E Vaccines in Healthy, HIV-Uninfected Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT01376726 COMPLETED Evaluating the Safety and Immune Response to an HIV Vaccine in Healthy, HIV-Uninfected Adults Who Have Participated in Previous HIV Vaccine Clinical Trials and in Adults Who Have Not Participated in Previous HIV Vaccine Clinical Trials
National Institute of Allergy and Infectious Diseases (NIAID)
NCT01783977 COMPLETED Evaluating the Safety and Immune Response to Three HIV Vaccine Schedules in Healthy, HIV-Uninfected Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT04041674 WITHDRAWN Evaluating the Safety and Immunogenicity of a Prime-boost Vaccine Regimen of GEO-D02 DNA and MVA/HIV62B With and Without B63521^11 gp120 and IHV01 gp120 Env Proteins in Healthy, HIV-uninfected Adult Participants
National Institute of Allergy and Infectious Diseases (NIAID)
NCT01159990 COMPLETED Antigenic Competition in HIV Preventive Vaccines
National Institute of Allergy and Infectious Diseases (NIAID)
NCT01578889 COMPLETED Evaluating the Safety of and Immune Response to HIV-MAG DNA Vaccine With or Without Plasmid IL-12 Adjuvant Delivered Intramuscularly Via Electroporation Followed by VSV-gag HIV Vaccine Boost in Healthy, HIV-Uninfected Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT01479296 COMPLETED Evaluating the Immune Response to a rAd5 HIV Vaccine Administered in Three Different Ways in Healthy, HIV-Uninfected Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00955006 COMPLETED Immune Response to an HIV DNA Plasmid Vaccine Prime Followed by Adenovirus Boost in HIV-uninfected Individuals
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00991354 COMPLETED Safety of and Immune Response to the PENNVAX-B DNA Vaccine With and Without IL-12 in HIV-uninfected Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00574600 COMPLETED Safety of and Immune Response to Two HIV Vaccines: SAAVI DNA-C2 Boosted With SAAVIMVA-C, in HIV-Negative Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00801697 COMPLETED Safety and Immune Response to Preventive HIV Immunization With Adenovirus Serotype 5 or 35 Vector
National Institute of Allergy and Infectious Diseases (NIAID)
NCT01423825 COMPLETED Evaluating the Safety and Immune Response to an HIV Vaccine Boost Following the Administration of Two HIV Vaccines, in HIV-Uninfected, Healthy Adults (Study Extension to HVTN 073/SAAVI 102)
National Institute of Allergy and Infectious Diseases (NIAID)
NCT03831945 TERMINATED Combination Therapy With VRC01 and 10-1074 in HIV-Infected Individuals Undergoing Sequential Treatment Interruptions
National Institute of Allergy and Infectious Diseases (NIAID)
NCT03382418 COMPLETED Evaluating the Safety and Immunogenicity of an HIV Vaccine (gp145 C.6980) in Healthy, HIV-Uninfected Adults in the United States
National Institute of Allergy and Infectious Diseases (NIAID)
NCT04027387 COMPLETED Dose Escalation Safety Study of TMB-365 in HIV-1 Infected Participants
TaiMed Biologics Inc.
NCT04757974 COMPLETED Low-dose Fostemsavir Extended Release Relative Bioavailability Study
ViiV Healthcare
NCT03976752 COMPLETED Body Compartment Pharmacokinetics of Anti-retroviral Agents That May be Considered for Future On-demand Peri-exposure HIV Prophylaxis Regimens
Emory University
NCT03783130 COMPLETED Dose, Safety, Tolerability, and Immunogenicity of an HIV-1 Vaccine, VRC-HIVRGP096-00-VP, With Alum in Healthy Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT03554408 COMPLETED First-in-human Study of 10-1074-LS Alone and in Combination With 3BNC117-LS
Rockefeller University
NCT03293290 COMPLETED Project EMPOWERING: Evidence-based PrEP for Justice-Involved Women and Their Risk Networks
Yale University
NCT03980691 COMPLETED Effect of Chidamide Combined With CAT-T or TCR-T Cell Therapy on HIV-1 Latent Reservoir
Guangzhou 8th People's Hospital
NCT04006704 COMPLETED Study to Assess the Acceptability of Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (D/C/F/TAF) Fixed-Dose Combination (FDC) Tablets in Human Immunodeficiency Virus Type 1 (HIV-1) Infected Pediatric Participants, Using Matching Placebo Tablets
Janssen Pharmaceutica N.V., Belgium
NCT01768962 COMPLETED Tenofovir Levels Following Local Application of Tenofovir Reduced-Glycerin 1% Gel
CONRAD
NCT03231943 COMPLETED GSK3640254 First Time in Human (FTIH) Study in Healthy Volunteers
ViiV Healthcare
NCT04016233 COMPLETED Tenofovir Rectal Douche to Prevent HIV Transmission
Johns Hopkins University
NCT03859739 COMPLETED Safety, Tolerability, Pharmacokinetics, and Anti-Retroviral Activity of MK-8558 Monotherapy in Anti-Retroviral-Naïve HIV-1 Infected Participants (MK-8558-002)
Merck Sharp & Dohme LLC
NCT03422172 COMPLETED A Safety, Tolerability, Acceptability, and Pharmacokinetic (PK) Study of Cabotegravir (CAB) in Healthy Human Immunodeficiency Virus (HIV)-Uninfected Chinese Men
ViiV Healthcare
NCT03899480 COMPLETED Adoptive Transfer of Haploidentical NK Cells and N-803
University of Minnesota
NCT03060447 COMPLETED Study to Evaluate the Safety and Efficacy of Vesatolimod in Antiretroviral Treated Human Immunodeficiency Virus (HIV-1) Infected Controllers
Gilead Sciences
NCT03270709 TERMINATED Effect of High-Dose Vitamin D3 in Smokers and Non-Smokers With and Without HIV
Emory University
NCT03739866 COMPLETED Study to Evaluate Safety, Pharmacokinetics, and Antiviral Activity of Lenacapavir Administered Subcutaneously in Human Immunodeficiency Virus (HIV) -1 Infected Adults
Gilead Sciences
NCT03204617 COMPLETED Safety and Immunogenicity Study of DNA.HTI, MVA.HTI and ChAdOx1.HTI in HIV-1-positive Patients (AELIX-002)
Aelix Therapeutics
NCT02325934 COMPLETED Bioequivalence of Crushed Stribild With a Normal Breakfast or With Drip Feed Compared to the Whole Tablet
Radboud University Medical Center
NCT04263142 COMPLETED A Relative Bioavailability and Food-Effect Study of GSK3640254 Tablet and Capsule Formulations in Healthy Participants
ViiV Healthcare
NCT02348775 COMPLETED Glutathione and Function in HIV Patients
Baylor College of Medicine
NCT03254277 COMPLETED 3BNC117-LS First-in-Human Phase 1 Study
Rockefeller University
NCT03663998 COMPLETED Optimising DNA Vaccinations in Healthy Volunteers
Imperial College London
NCT03697226 COMPLETED Study of Topical ABI-1968 in Subjects With Precancerous Cervical Lesions From Human Papillomavirus (HPV) Infection.
Antiva Biosciences
NCT02549040 COMPLETED Bioavailability of Doravirine (MK-1439) Experimental Nano Formulations in Healthy Adults (MK-1439-046)
Merck Sharp & Dohme LLC
NCT02569346 COMPLETED Bioequivalence Study of CRushed TriUMeq With or Without Drip Feed Compared to the Whole Tablet
Radboud University Medical Center
NCT02565888 COMPLETED A Drug-drug Interaction Study Between Daclatasvir and Atazanavir/Ritonavir or Atazanavir/Cobicistat
Radboud University Medical Center
NCT01288417 COMPLETED Pharmacokinetic Study of the HCV Protease Inhibitor Boceprevir and the HIV Integrase Inhibitor Raltegravir
Radboud University Medical Center
NCT00977301 COMPLETED Interaction Between Fosamprenavir/Ritonavir and a Single-dose Olanzapine (FORZA)
Radboud University Medical Center
NCT01246804 COMPLETED The Influence of GINkGo Biloba on the Pharmacokinetics of the UGT Substrate raltEgraviR (GINGER)
Radboud University Medical Center
NCT00817765 COMPLETED Pharmacokinetic Study of Posaconazole Boosted Fosamprenavir
Radboud University Medical Center
NCT00665951 COMPLETED Pharmacokinetic Study of Two Generic Co-formulations of Lopinavir/Ritonavir for HIV Infected Children (SURF)
Radboud University Medical Center
NCT02275065 COMPLETED Study to Evaluate Safety, Pharmacokinetics, and Antiviral Activity of Bictegravir (GS-9883) in Human Immunodeficiency Virus (HIV)-1 Infected Participants
Gilead Sciences
NCT03234036 COMPLETED A Two-part Study to Compare a Tablet and Capsule Formulation of GSK2838232 With and Without Food, and to Assess the Safety and Drug Levels of Repeated Once-daily Doses of GSK2838232 Without Ritonavir
GlaxoSmithKline
NCT03015181 COMPLETED VRC 605: Safety and Pharmacokinetics of a Human Monoclonal Antibody, VRC-HIVMAB075-00-AB (VRC07-523LS), Administered Intravenously or Subcutaneously to Healthy Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT01779687 COMPLETED Pharmacokinetic Drug Interaction Study Between Raltegravir and Atorvastatin.
Radboud University Medical Center
NCT03368053 COMPLETED Long-term Immunogenicity of the HIV gp120-NefTat/AS01B Vaccine (GSK SB732461)
GlaxoSmithKline
NCT00665717 COMPLETED The Influence of Raltegravir on Pravastatin Pharmacokinetics(GRAPPA)
Radboud University Medical Center
NCT00618241 COMPLETED Pharmacokinetic Study on Raltegravir and Lamotrigine
Radboud University Medical Center
NCT01978782 COMPLETED Pharmacokinetic Drug-drug Interaction Study Between RaltEgravir and CITALopram in Healthy Subjects (RECITAL).
Radboud University Medical Center
NCT03615183 COMPLETED A Study of MK-8527 in Human Immunodeficiency Type 1 Virus (HIV-1) Infected Participants (MK-8527-002)
Merck Sharp & Dohme LLC
NCT03149848 COMPLETED Effect of Rifabutin on the Pharmacokinetics of Oral Cabotegravir in Healthy Subjects
ViiV Healthcare
NCT03205917 COMPLETED A Clinical Trial of PGDM1400 and PGT121 and VRC07-523LS Monoclonal Antibodies in HIV-infected and HIV-uninfected Adults
International AIDS Vaccine Initiative
NCT02354937 COMPLETED Pharmacokinetics Study of GSK1265744 in Subjects With Severe Renal Impairment
ViiV Healthcare
NCT03472963 COMPLETED Body Compartment Pharmacokinetics of Anti- Retroviral Agents That May be Used for Future HIV Post- Exposure Prophylaxis.
Emory University
NCT03984825 COMPLETED Effect of GSK3640254 on the Pharmacokinetics of a Combination Oral Contraceptive
ViiV Healthcare
NCT04128293 TERMINATED A Relative Bioavailability and Food-Effect Study of GSK3640254 Tablet and Capsule Formulations in Healthy Participants
ViiV Healthcare
NCT01695954 COMPLETED Pharmacokinetic Study of Pitavastatin and Ritonavir-Boosted Darunavir or Efavirenz
NYU Langone Health
NCT02354950 COMPLETED A Study to Evaluate Pharmacokinetic (PK) and Safety of GSK1265744 in Subjects With Hepatic Impairment and Control Healthy Volunteers
ViiV Healthcare
NCT03921723 COMPLETED Dolutegravir Pediatric Liquid Formulation Study
ViiV Healthcare
NCT01249443 TERMINATED Paclitaxel and Carboplatin in Treating Patients With Metastatic or Recurrent Solid Tumors and HIV Infection
AIDS Malignancy Consortium
NCT04322214 COMPLETED Clinical Trial to Evaluate Pharmacological Interactions Between γ-hydroxybutyrate (GHB) and Cobicistat
Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia
NCT03719053 COMPLETED Single Dose Truvada Study
Johns Hopkins University
NCT02009462 COMPLETED Artefill for the Treatment of HIV-associated Facial Lipoatrophy
Gerald Pierone, Jr. M.D.
NCT03984838 COMPLETED Study to Evaluate Pharmacokinetics, Safety and Tolerability of Dolutegravir and Rilpivirine (JULUCA™) 50 Milligram (mg)/25 mg Tablets in Healthy Subjects of Japanese Descent
ViiV Healthcare
NCT03063788 COMPLETED Imaging the HIV Reservoir
Bayside Health
NCT02478463 COMPLETED Pharmacokinetic Study of Cabotegravir Long-acting in Healthy Adult Volunteers
ViiV Healthcare
NCT03329560 COMPLETED Safety of FMT Using Oral Encapsulated PRIM-DJ2727 in HIV
The University of Texas Health Science Center, Houston
NCT03110549 TERMINATED Study of the Safety, Tolerability and Pharmacokinetics of TMB-607 in HIV-Negative Volunteers
TaiMed Biologics Inc.
NCT03836729 COMPLETED Study to Evaluate the Effect of GSK3640254 on the Pharmacokinetics of Tenofovir Alafenamide/Emtricitabine
ViiV Healthcare
NCT03886701 COMPLETED Doravirine, Rifapentine and Isoniazid Interaction
Walter K. Kraft
NCT01031472 COMPLETED A Study to Assess Relative Bioavailability and Food Effect of New Formulations of GSK2248761
ViiV Healthcare
NCT03816696 COMPLETED Study to Evaluate the Pharmacokinetic (PK) Interactions Between GSK3640254 and Dolutegravir (DTG)
ViiV Healthcare
NCT01894776 COMPLETED A Drug Interaction Study Investigating the Effect of Rifabutin on the Pharmacokinetics of Maraviroc
Ottawa Hospital Research Institute
NCT02170246 COMPLETED Analysis of Telmisartan Administered With Antiretroviral Therapy (ART) in Patients With Acute HIV Infection
Yale University
NCT03552536 COMPLETED MK-8583 Single Dose Study in Human Immunodeficiency Virus Type 1 (HIV-1) Infected Participants (MK-8583-002)
Merck Sharp & Dohme LLC
NCT03753867 WITHDRAWN RA Effect on Cell Surface Molecules in Vivo
Ottawa Hospital Research Institute
NCT01859325 COMPLETED Therapeutic Vaccine for HIV
National Institute of Allergy and Infectious Diseases (NIAID)
NCT02788175 COMPLETED Vedolizumab (Anti-alpha4beta7) in Subjects With HIV Infection Undergoing Analytical Treatment Interruption
National Institute of Allergy and Infectious Diseases (NIAID)
NCT02858401 COMPLETED Safety and Biological Activity of Vesatolimod in HIV-1 Infected, Virologically Suppressed Adults
Gilead Sciences
NCT02191098 COMPLETED Proof of Principle Study of Pulse Dosing of IL-15 to Deplete the Reservoir in HIV Infected People
University of Minnesota
NCT02599896 COMPLETED Safety and Pharmacokinetics of a Human Monoclonal Antibody, VRC-HIVMAB080-00-AB (VRC01LS), With Broad HIV-1 Neutralizing Activity, Administered Intravenously or Subcutaneously to Healthy Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00709605 COMPLETED Phase I Study of HIV Adenoviral Vector Vaccine in Healthy Subjects Using Needle or Biojector Injection
National Institute of Allergy and Infectious Diseases (NIAID)
NCT01993706 COMPLETED Study of the Safety and Pharmacokinetics of a Human Monoclonal Antibody, VRC-HIVMAB060-00-AB (VRC01), Administered Intravenously or Subcutaneously to Healthy Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT01950325 COMPLETED VRC 601: A Phase I, Open-Label, Dose-Escalation Study of the Safety and Pharmacokinetics of a Human Monoclonal Antibody, VRC HIVMAB060-00-AB (VRC01), With Broad HIV-1 Neutralizing Activity, Administered Intravenously or Subcutaneously to HIV-Infected...
National Institute of Allergy and Infectious Diseases (NIAID)
NCT01386489 COMPLETED Immune Responses to Two Experimental HIV Vaccines in Healthy Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT03441984 COMPLETED To Assess the Relative Bioavailability (BA) of TRIUMEQ® and Dolutegravir and Lamivudine (DTG/3TC) Pediatric Dispersible Tablet Formulations in Healthy Volunteers
ViiV Healthcare
NCT01148004 COMPLETED The Influence of Ritonavir, Alone and in Combination With Lopinavir, on Fenofibric Acid Pharmacokinetics in Healthy Volunteers
National Institutes of Health Clinical Center (CC)
NCT02527460 TERMINATED Anakinra, A Recombinant Human IL-1 Receptor Antagonist for Neuroinflammation in HIV-1 Infection
National Institute of Neurological Disorders and Stroke (NINDS)
NCT03346499 COMPLETED Adoptive Transfer of Haploidentical Natural Killer Cells and IL-2
University of Minnesota
NCT01966900 COMPLETED The Safety and Immunogenicity of a Potential HIV Vaccine
Imperial College London
NCT00982878 COMPLETED The Maraviroc Central Nervous System (CNS) Study
Imperial College London
NCT01348763 COMPLETED The Maraviroc Darunavir/Ritonavir Once Daily Pharmacokinetic Study
Imperial College London
NCT03351699 COMPLETED Single-Dose Study of MK-4250 Monotherapy in Anti-Retroviral Therapy-Naive, Human Immunodeficiency Virus (HIV)-1 Infected Participants (MK-4250-002)
Merck Sharp & Dohme LLC
NCT03082690 COMPLETED ImQuest (IQP) DuoGel Phase 1 Pharmacokinetic Study
Johns Hopkins University
NCT00982553 COMPLETED The Raltegravir and Ribavirin Pharmacokinetics (PK) Study
Imperial College London
NCT02400307 COMPLETED Pharmacokinetics of Bictegravir in Adults With Normal and Impaired Renal Function
Gilead Sciences
NCT00991224 COMPLETED Redirected High Affinity Gag-Specific Autologous T Cells for HIV Gene Therapy
University of Pennsylvania
NCT02208167 COMPLETED Phase I Study of HIV 1 Antigen Expanded Specific T Cell Therapy
University of North Carolina, Chapel Hill
NCT02707900 TERMINATED Pilot Trial of the Effect of Vorinostat and AGS-004 on Persistent HIV-1 Infection
University of North Carolina, Chapel Hill
NCT02960581 COMPLETED Safety, PK and Antiviral Activity of PGT121 Monoclonal Antibody in HIV-uninfected and HIV-infected Adults
International AIDS Vaccine Initiative
NCT02985996 COMPLETED Body Compartment PK for New HIV Pre-exposure Prophylaxis Modalities
Emory University
NCT03289676 COMPLETED Storytelling Narrative Communication Intervention for Smoking Cessation in Women Living With HIV
University of Massachusetts, Boston
NCT03575962 COMPLETED A Study to Compare the Relative Bioavailability of Two Different Formulations of GSK3640254
ViiV Healthcare
NCT01787994 COMPLETED Redirected MazF-CD4 Autologous T Cells for HIV Gene Therapy
University of Pennsylvania
NCT02217904 COMPLETED A Study of Islatravir (MK-8591) in Anti-Retroviral Therapy-Naive, Human Immunodeficiency Virus-1 Infected Participants (MK-8591-003)
Merck Sharp & Dohme LLC
NCT01231529 COMPLETED GSK1349572 Hepatic Impairment Study
ViiV Healthcare
NCT02767193 COMPLETED Safety and Immunogenicity of a Vaccine Dendritic Cell-based Pulsed With Autologous Heat-inactivated in HIV-1 Infected Patients
Judit Pich Martínez
NCT03677960 TERMINATED Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) Infection
Antiva Biosciences
NCT03095638 COMPLETED Bioavailability Study of 10 Milligram (mg) and 5 mg Tablets Versus Conventional Tablets of Dolutegravir
ViiV Healthcare
NCT03762772 COMPLETED Safety, PK, and PD Study of a Vaginal Insert Containing TAF and EVG
CONRAD
NCT02741557 COMPLETED Bioequivalence Study of a Fixed-dose Combination (FDC) of Dolutegravir (DTG) and Rilpivirine (RPV)
ViiV Healthcare
NCT03188523 COMPLETED Activity of MK-8504 in Anti-retroviral-naïve, Human Immunodeficiency Virus 1 (HIV-1) Infected Participants (MK-8504-002)
Merck Sharp & Dohme LLC
NCT02715700 COMPLETED Effects of Doravirine (MK-1439) on Methadone Pharmacokinetics in Methadone-Maintained Participants (MK-1439-045)
Merck Sharp & Dohme LLC
NCT01068925 COMPLETED Drug Interaction Study Between GSK1349572 and Tipranavir/Ritonavir in Healthy Volunteers
ViiV Healthcare
NCT02997969 COMPLETED Safety and Immune Response to a Clade C DNA HIV Vaccine
National Institute of Allergy and Infectious Diseases (NIAID)
NCT02109354 COMPLETED Safety of and Immune Response to Vaccination With 2 Experimental HIV Vaccines in Healthy Adults
HIV Vaccine Trials Network
NCT01418235 COMPLETED Safety of and Immune Response to a DNA HIV Vaccine Boosted With a Modified Vaccinia HIV Vaccine and Protein HIV Vaccine in Healthy Adults
HIV Vaccine Trials Network
NCT02563509 COMPLETED Reconstitution of HIV-specific Immunity Against HIV
Guangzhou 8th People's Hospital
NCT02993237 COMPLETED Study to Assess the Acceptability/Swallowability of DRV-Containing FDC Tablets in HIV-1 Infected Adolescents, Using Matching Placebo Tablets
Janssen Research & Development, LLC
NCT02388594 COMPLETED A Phase I Study of T-Cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases SB-728mR in HIV-Infected Patients
University of Pennsylvania
NCT03892161 TERMINATED Clinical Evaluation of Adjusted Doses of Darunavir/Ritonavir With Rifampicin in HIV-infected Volunteers
University of Cape Town
NCT03078556 COMPLETED Bioequivalence Study of Fixed Dose Versus Single Entities of Dolutegravir and Lamivudine
ViiV Healthcare
NCT01195974 TERMINATED A Study to Evaluate the Pharmacokinetics of an Oral Contraceptive When Co-administered With GSK2248761 in Healthy Adult Female Subjects.
ViiV Healthcare
NCT01466985 COMPLETED A Study of Doravirine (MK-1439) in Human Immunodeficiency Virus Type 1 (HIV-1)-Infected Participants (MK-1439-005)
Merck Sharp & Dohme LLC
NCT00842634 COMPLETED Autologous T-Cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases SB-728 for HIV
University of Pennsylvania
NCT03202992 COMPLETED Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) Infection
Antiva Biosciences
NCT03391375 COMPLETED Evaluation of the Effect of Late Boost on HIV-uninfected Vaccines From EV06 Trial
EuroVacc Foundation
NCT03234400 COMPLETED A Phase 1, Randomized Pharmacokinetics and Safety Study of Extended Duration Dapivirine Vaginal Rings
International Partnership for Microbicides, Inc.
NCT02089659 COMPLETED A Study to Investigate the Influence of Hepatic Insufficiency on the Pharmacokinetics of Doravirine (MK-1439) (MK-1439-019)
Merck Sharp & Dohme LLC
NCT02378922 WITHDRAWN Gene-Modified HIV-Protected Stem Cell Transplant in Treating Patients With HIV-Associated Lymphoma
Fred Hutchinson Cancer Center
NCT02875119 COMPLETED Study to Evaluate the Safety of Griffithsin in a Carrageenan Gel in Healthy Women
Population Council
NCT02343666 WITHDRAWN HIV-Resistant Gene Modified Stem Cells and Chemotherapy in Treating Patients With Lymphoma With HIV Infection
Fred Hutchinson Cancer Center
NCT02547870 COMPLETED A Study to Evaluate the Pharmacokinetic Effects of Different Storage Conditions for a Long-Acting Nanosuspension of Rilpivirine on Pharmacokinetics
Janssen Infectious Diseases BVBA
NCT03118661 WITHDRAWN Maraviroc on HIV-1 Infected Subjects Who Require Allogeneic Hematopoietic Cell Transplant
Washington University School of Medicine
NCT02652546 COMPLETED CC-11050 in Human Immunodeficiency Virus-1-Infected Adults With Suppressed Plasma Viremia on Antiretroviral Therapy (APHRODITE)
National Institute of Allergy and Infectious Diseases (NIAID)
NCT03706924 COMPLETED Comparative Study of PK and BE of VM-1500FDC (Fixed-dose Combination) and Elpida® With Truvada® сo-administrated 1 Daily Fasting in Healthy Subjects
Viriom
NCT02362217 COMPLETED A Study to Assess the Safety of HIV and Hep C Vaccine Candidates When Given Separately or in Combination
University of Oxford
NCT02489487 COMPLETED Study in Healthy Volunteers to Investigate the Safety, Tolerability and Pharmacokinetics of VM-1500
Viriom
NCT01353898 TERMINATED Study of MK-1972 in Human Immunodeficiency Virus (HIV)-1 Infected Participants Who Have Not Previously Received Antiretroviral Therapy (MK-1972-003)
Merck Sharp & Dohme LLC
NCT02006264 COMPLETED Safety and Pharmacokinetics (PK) of a Polyurethane Tenofovir Disoproxil Fumarate (TDF) Vaginal Ring
Albert Einstein College of Medicine
NCT02473367 COMPLETED The Effect of Antacids on the Pharmacokinetics (PK) of Raltegravir in Human Immunodeficiency Virus (HIV)-Infected Participants (MK-0518-824)
Merck Sharp & Dohme LLC
NCT01930045 COMPLETED A Pharmacokinetic Study to Evaluate the Effect of MAALOX on Raltegravir (MK-0518) in Human Immunodeficiency Virus (HIV)-Infected Participants (MK-0518-295)
Merck Sharp & Dohme LLC
NCT02825797 COMPLETED 3BNC117 and 10-1074 in HIV-infected Individuals
Rockefeller University
NCT02762617 TERMINATED Safety and Pharmacokinetics (PK) of a Polyurethane Tenofovir Disoproxil Fumarate (TDF) Vaginal Ring (TDF IVR-002)
Marla Keller
NCT03060785 COMPLETED Finding the Right Tenofovir/Emtricitabine Regimen for Pre-Exposure Prophylaxis (PrEP) in Transgender Women
Johns Hopkins University
NCT02578277 COMPLETED Study on Effects of BMS-955176 on the Pharmacokinetics of Probe Substrates
ViiV Healthcare
NCT01479361 COMPLETED Antiretroviral Drug Interaction Study in Volunteers With HIV
National Institutes of Health Clinical Center (CC)
NCT02855346 COMPLETED PK and Safety Study of Vaginal Rings Containing Dapivirine and Levonorgestrel
International Partnership for Microbicides, Inc.
NCT03094507 COMPLETED The Pharmacokinetics of Dolutegravir, Darunavir/Cobocistat When Co-administered in Healthy Volunteers
St Stephens Aids Trust
NCT02674581 COMPLETED A Study of the Pharmacokinetics and Safety of BMS-663068 Administered in Subjects With Normal Renal Function and With Mild, Moderate, Severe and End Stage Renal Dysfunction (ESRD)
ViiV Healthcare
NCT02128217 COMPLETED Sofosbuvir-Containing Regimens Without Interferon For Treatment of Acute Hepatitis C Virus (HCV) Infection
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
NCT02206711 COMPLETED Study of the Absorption, Metabolism, and Route of Elimination of a Novel Class of Anti-HIV 1 Drugs (BMS-955176) in Humans.
ViiV Healthcare
NCT02234882 COMPLETED Study on Pharmacokinetics
ViiV Healthcare
NCT02608918 COMPLETED Taste Properties of HIV Inhibitor
ViiV Healthcare
NCT02157467 COMPLETED Study of Combined Oral Contraceptive Effects in Female Subjects
ViiV Healthcare
NCT02824536 COMPLETED 3BNC117 and 10-1074 in HIV Uninfected Adults
Rockefeller University
NCT01755741 COMPLETED Functionality of Male Condoms With a Silicone Elastomer Vaginal RIng
International Partnership for Microbicides, Inc.
NCT01123915 TERMINATED A Safety and Immunogenicity Study of 3 Doses of Opal Immunotherapy in HIV Infected People
Medicines Development for Global Health
NCT02808949 COMPLETED Pharmacokinetic Study of the Dapivirine Vaginal Ring in Lactating Women
International Partnership for Microbicides, Inc.
NCT02818348 COMPLETED Clinical Trial to Evaluate Drug-drug Interactions Between Darunavir/Cobicistat and Etravirine in Hiv- Infected Patients
Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia
NCT01016730 COMPLETED Bortezomib in Treating Patients With Relapsed or Refractory AIDS-Related Kaposi Sarcoma
National Cancer Institute (NCI)
NCT02904369 COMPLETED PK and PD Study of Oral F/TAF for HIV Prevention
CONRAD
NCT03186482 COMPLETED RIFT: Effect of Rifampicin on Plasma PK of FTC, TAF and Intracellular TFV-DP & FTC-TP
St. Stephens Clinical Research
NCT02511990 COMPLETED A Study of the Safety, Pharmacokinetics and Antiretroviral Activity of 10-1074
Rockefeller University
NCT02277600 COMPLETED A Phase 1 Antiretroviral Drug-Drug Interaction Study in Healthy Volunteers (DDI)
ViiV Healthcare
NCT02697851 TERMINATED Pharmacokinetic Effect of Evotaz/Microgynon Co-administration
St Stephens Aids Trust
NCT02527005 COMPLETED A Comparative Study of Azithromycin and S-P as Prophylaxis in Pregnant HIV+ Patients
University of Ibadan
NCT02556268 COMPLETED Interaction With HIV Antiretroviral Agents
Bayer
NCT01378156 COMPLETED A Safety and Immunogenicity Study of a Plasmid DNA Prime and MVA Boost Vaccine in HIV-1 Infected Adults on ART
GeoVax, Inc.
NCT02471326 COMPLETED VRC-HIVMAB060-00-AB (VRC01) in People With Chronic HIV Infection Undergoing Analytical Treatment Interruption
National Institute of Allergy and Infectious Diseases (NIAID)
NCT02499874 COMPLETED SSAT063- Pharmacokinetics of Efavirenz 400 mg Once Daily During Pregnancy in HIV-1 Infected Women
St Stephens Aids Trust
NCT01755754 COMPLETED A Trial to Assess the Functionality of Female Condom With a Silicone Elastomer Vaginal Ring
International Partnership for Microbicides, Inc.
NCT02138084 COMPLETED Drug-drug Interaction (DDI) Rifabutin
ViiV Healthcare
NCT02480894 COMPLETED A Open-label, Drug-Drug Interaction With Maraviroc (DDI)
ViiV Healthcare
NCT02467335 COMPLETED Single-dose Pharmacokinetics of BMS-626529, Administered as BMS-663068, in Subjects With Hepatic Impairment Compared to Healthy Subjects
ViiV Healthcare
NCT01098526 COMPLETED GSK1349572 Drug Interaction Study With Efavirenz
ViiV Healthcare
NCT02095886 COMPLETED Relative Bioavailability Study With BMS-955176
ViiV Healthcare
NCT01101893 COMPLETED A Drug Interaction Study Evaluating GSK2248761 and Raltegravir Pharmacokinetics in Healthy Adult Subjects
ViiV Healthcare
NCT03054207 TERMINATED Impact of Antiretroviral Treatment on Pharmacokinetics and Pharmacodynamics of Thienopyridines in Healthy Volunteers and HIV Patients
Jules Desmeules
NCT02508064 COMPLETED Bioavailability of BMS-626529 in Healthy Subjects From Prototype Low Dose Extended Release Formulations (Part 1) and Prototype Extended Release Multi-particulate Formulations (Part 2) of BMS-663068 Relative to 600 mg Extended Release Tablet
ViiV Healthcare
NCT02666053 COMPLETED A Study to Assess the Effect of High Fat Meal and Increased Gastric pH on the Bioavailability of an Extended Release Formulation of BMS-663068 in Healthy Subjects
ViiV Healthcare
NCT02346084 COMPLETED Safety and Pharmacokinetic Study of Oral Maraviroc and Maraviroc 1% Gel in HIV-1 Seronegative Adults
International Partnership for Microbicides, Inc.
NCT01548560 COMPLETED Assessing the Safety of Dapivirine Gel and Film Formulations
International Partnership for Microbicides, Inc.
NCT01731574 COMPLETED DDI Potential: Dapivirine Vaginal Ring and Miconazole Nitrate
International Partnership for Microbicides, Inc.
NCT01103687 COMPLETED Evaluating the Safety and Immune Response of an Adenovirus-Based HIV Vaccine in HIV-Uninfected Adults
National Institute of Allergy and Infectious Diseases (NIAID)
NCT02920827 COMPLETED Safety and Pharmacokinetic Trial in Healthy HIV-Negative Women to Assess the Delivery of Dapivirine From a Vaginal Ring
International Partnership for Microbicides, Inc.
NCT02858024 COMPLETED A Trial In Healthy HIV-Negative Women To Assess The Effect Of Menses And Tampon Use On The Pharmacokinetics Of Dapivirine, Delivered By Dapivirine Vaginal Ring-004, Containing 25 Mg Of Dapivirine
International Partnership for Microbicides, Inc.
NCT00705926 COMPLETED Effectiveness of Antiretroviral Therapy During Acute HIV Infection
Massachusetts General Hospital
NCT02847286 COMPLETED To Assess the Drug-drug Interaction Potential Between Dapivirine Vaginal Ring-004, Containing 25 mg of Dapivirine, and Clotrimazole 10 mg/g (1%)
International Partnership for Microbicides, Inc.
NCT02877979 COMPLETED Evaluate the Safety & Assess Local and Systemic PK of DS003 Vaginal Tablets Administered to Healthy HIV-negative Women
International Partnership for Microbicides, Inc.
NCT02154360 COMPLETED Pharmacokinetic Characteristics and Anti-Inflammatory Effects of Aprepitant In HIV-Infected Subjects
University of Pennsylvania
NCT02033109 COMPLETED Safety, Pharmacokinetics and Acceptability of PC-1005 for Vaginal Use
Population Council
NCT02576119 TERMINATED A Study to Determine the Effect of Multiple Doses of BMS-955176 on the Electrocardiograph of Healthy Subjects
ViiV Healthcare
NCT02666001 COMPLETED A Study to Assess the Drug-drug Interaction of BMS 663068 With Methadone and Also With Buprenorphine/Naloxone
ViiV Healthcare
NCT02063360 COMPLETED DDI Study of BMS-663068 With Etravirine (ETR) and/or Darunavir (DVR) + Ritonavir (RTV)
ViiV Healthcare
NCT02893488 COMPLETED Relative Bioavailability Study of a Fixed-dose Combination Dolutegravir/Abacavir/Lamivudine Dispersible Tablet
ViiV Healthcare
NCT00711386 COMPLETED GSK706769 Repeat Dose Study
GlaxoSmithKline
NCT02164045 COMPLETED Study to Evaluate the Effect of Food on the Pharmacokinetics of BMS-626529
ViiV Healthcare
NCT02480881 COMPLETED A Drug-drug Interaction Study Between BMS-663068 and Oral Contraceptives in Healthy Female Volunteers (DDI)
ViiV Healthcare
NCT02805556 COMPLETED Absolute Bioavailability of BMS-626529 After Oral and Intravenous Dosing
ViiV Healthcare
NCT00723775 COMPLETED GSK706769/KALETRA Drug-drug Interaction Study
GlaxoSmithKline
NCT01503255 COMPLETED A Stage 2 Cognitive-behavioral Trial: Reduce Alcohol First in Kenya Intervention
Brown University
NCT00936793 COMPLETED Drug Interaction Study Between Inhaled Beclomethasone and Protease Inhibitors in Healthy Volunteers
National Institutes of Health Clinical Center (CC)
NCT01896622 COMPLETED The Interaction of Two HIV Medications With Blood Clot Medications in Healthy Volunteers
National Institutes of Health Clinical Center (CC)
NCT00944307 COMPLETED Effect of Antacids on the Pharmacokinetics of Raltegravir
University of Colorado, Denver
NCT01275443 COMPLETED Study in Healthy Volunteers of the Safety and Metabolism of Different Doses of the Anti-HIV Drug TMC278LA.
St Stephens Aids Trust
NCT00796770 COMPLETED Vaccination of HIV-1 Infected Patients With Dendritic Cells in Addition to Antiretroviral Treatment - (DALIA Trial)
Baylor Research Institute
NCT01098513 COMPLETED GSK1349572 Relative Bioavailability Study
ViiV Healthcare
NCT01209117 COMPLETED A Study to Assess the Relative Bioavailability of Tablet Formulations of GSK2248761 in Healthy Adult Subjects. SGN114435
ViiV Healthcare
NCT01231542 COMPLETED Phase 1, Open Label, Two Arm, Fixed Sequence Study to Evaluate the Effect of Rifampin and Rifabutin on GSK1349572 Pharmacokinetics in Healthy Male and Female Volunteers
ViiV Healthcare
NCT02895893 COMPLETED PrEP SMART Phase I Trial
Duke University
NCT02289482 TERMINATED A Single Dose Pharmacokinetic (PK) and Safety Study of GSK2838232 With and Without Ritonavir (RTV) Conducted in Healthy Subjects
GlaxoSmithKline
NCT02859259 COMPLETED A Study of the Relative Bioavailability of BMS-626529 Administered as BMS-663068 From 150mg Low-dose Extended-release Tablets Compared to 600mg Reference Extended-release Tablets in Healthy Subjects
ViiV Healthcare
NCT01802918 COMPLETED Single Dose Escalation Study of GSK2838232 in Healthy Subjects
GlaxoSmithKline
NCT02289495 TERMINATED A Repeat Dose Pharmacokinetic (PK) and Safety Study of GSK2838232 With and Without Ritonavir (RTV) Conducted in Healthy Subjects
GlaxoSmithKline
NCT02256592 COMPLETED Fecal Microbiota Transplantation in HIV
University of California, San Francisco
NCT02042248 COMPLETED A Phase I Study to Evaluate the Immunologic Response and Virologic Impact of AGS-004
Cynthia L Gay, MD
NCT01052701 COMPLETED Drug Interaction Study With Ribavirin and Abacavir in Male Subjects With Hepatitis C Who Have Failed Ribavirin Treatment
Johns Hopkins University
NCT02273947 COMPLETED Food Effect Study With BMS-955176
ViiV Healthcare
NCT01563328 COMPLETED A Study to Evaluate the Effect of Boceprevir and Telaprevir on Dolutegravir Pharmacokinetics in Healthy Adult Subjects (ING115697).
ViiV Healthcare
NCT01622673 COMPLETED A Pharmacokinetic Study to Evaluate the Effect of Antacids on Raltegravir (MK-0518) in HIV-Infected Participants (MK-0518-247)
Merck Sharp & Dohme LLC
NCT01000818 COMPLETED A Study to Evaluate the Effect of Famotidine and Omeprazole on MK0518 (Raltegravir) Pharmacokinetics in Human Immunodeficiency Virus (HIV)-Infected Patients (0518-054)
Merck Sharp & Dohme LLC
NCT01923610 COMPLETED Safety and Immunological Response of a Boosting Dose of MVA-B in Healthy Volunteers After 4 Years of Receiving MVA-B
Hospital Clinic of Barcelona
NCT00667433 COMPLETED Raltegravir as Early Therapy in African-Americans Living With HIV Study
David A Wohl, MD
NCT02812329 COMPLETED Intervention to Encourage HIV Testing and Counseling Among Adolescents
Yale University
NCT03044379 WITHDRAWN Dapivirine Gel Rectal Safety and PK Study
International Partnership for Microbicides, Inc.
NCT02715479 COMPLETED A Study to Evaluate the Effect of BMS-955176 on Pharmacokinetics of Dolutegravir and the Effect of Dolutegravir on the Pharmacokinetics of BMS-955176
ViiV Healthcare
NCT01209065 COMPLETED GSK1349572 Drug Interaction Study With Fosamprenavir/Ritonavir
ViiV Healthcare
NCT02795754 COMPLETED Single and Repeated Dose Escalation Study of GSK2838232
GlaxoSmithKline
NCT02738931 COMPLETED Relative Bio-availability Study of Dolutegravir and Lamivudine Fixed Dose Combinations
ViiV Healthcare
NCT02342223 COMPLETED Voluma Filler Agent For The Treatment of HIV-associated Facial Lipoatrophy
Jared Jagdeo, MD, MS
NCT02799264 COMPLETED A Study to Evaluate the Effect of High Fat Meal on Cabotegravir
ViiV Healthcare
NCT02018510 COMPLETED A Phase 1, Open Label, Dose-escalation Study of the Safety, Pharmacokinetics and Antiretroviral Activity of 3BNC117
Rockefeller University
NCT01040091 COMPLETED Evaluation of the Cellular Pharmacology of Tenofovir and Emtricitabine According to HIV Infection Status
National Institute of Allergy and Infectious Diseases (NIAID)
NCT02631473 SUSPENDED PK of Efavirenz & Lopinavir Nano-formulations in Healthy Volunteers
St Stephens Aids Trust
NCT02366013 COMPLETED Trial of the Safety and Immunogenicity of an Oral, Replicating Ad26 Vectored HIV-1 Vaccine
International AIDS Vaccine Initiative
NCT01638650 COMPLETED A Study of Ritonavir-Boosted Invirase (Saquinavir) in Treatment-Naïve HIV-1 Infected Patients
Hoffmann-La Roche
NCT00908414 WITHDRAWN PEPI-TiDP23-C104 is a First in Human Study With a Single Dose Escalation Part and a Multiple Dosing Part for Compounds TMC589337 and TMC589354.
Tibotec Pharmaceuticals, Ireland
NCT01854853 COMPLETED Brazilian HIV/Sexually Transmitted Infection (STI) Prevention for Adolescents With Mental Health Disorder
New York State Psychiatric Institute
NCT02242799 COMPLETED Dolutegravir Interactions With Artemisinin-based Combination Therapies
University of Liverpool
NCT01922284 COMPLETED Investigating Immunisation Strategies of DNA, MVA and CN54rgp140 Adjuvanted With GLA-AF to Maximise Antibody Responses
Imperial College London
NCT02569697 COMPLETED Development of Adherence Biomarkers for Multiple Microbicide and Multipurpose Prevention Technology (MPT) Dosage Forms
CONRAD
NCT02722343 COMPLETED Exploratory Pharmacodynamic Study of Tenofovir-Based Products
CONRAD
NCT00775424 COMPLETED PENNVAX-B With or Without IL-12 or IL-15 as a DNA Vaccine for HIV Infection
University of Pennsylvania
NCT02219217 COMPLETED SSAT061: PK of DTG and EVT/COBI in Healthy Volunteers
St Stephens Aids Trust
NCT01648257 COMPLETED Relative Bioavailability Study of GSK1265744 Formulations
ViiV Healthcare
NCT01989663 COMPLETED A Phase I Trial to Assess the Safety of Tenofovir Gel and Film Formulations: FAME 04
CONRAD
NCT02373930 COMPLETED Relative Oral Bioavailability Study of Different Fixed Dose Combinations of Dolutegravir and Rilpivirine in Healthy Subjects
ViiV Healthcare
NCT01024842 TERMINATED Safety and Immunogenicity of MVA.HIVconsv in HIV-1 Seropositive Adults on HAART
University of Oxford
NCT02456558 COMPLETED Evaluation of the Safety, Efficacy, and Pharmacokinetics of Intravenous Deferiprone in HIV-Positive Subjects
ApoPharma
NCT01300988 COMPLETED Effects of Treatment With Aprepitant (Emend®) in HIV Infected Individuals. 375 mg Dose
University of Pennsylvania
NCT01329744 TERMINATED Effects of IGF-I in HIV Metabolic Disease
University of Texas Southwestern Medical Center
NCT02589158 COMPLETED SSAT067 PK of Atazanavir/Cobicistat and Darunavir/Cobicistat
St Stephens Aids Trust
NCT01441193 TERMINATED A Phase I Safety and Immunogenicity Preventive Vaccine Trial Based on the HIV-1 Tat and V2-deleted Env Proteins (ISS P-002)
Barbara Ensoli, MD
NCT01784302 COMPLETED The Effect of Antacids and Multivitamins on Raltegravir
Helen Reynolds
NCT01889719 COMPLETED A Phase I Study to Evaluate the Safety and Immunogenicity of Heterologous Boost Immunizations With MVA-CMDR
Rockefeller University
NCT02527941 COMPLETED Effect of Bacterial Vaginosis on HIV Susceptibility and Female Genital Immunology
University of Toronto
NCT02376582 COMPLETED Safety and Immunogenicity Study of a DNA Vaccine Combined With Protein Vaccine Against HIV/AIDS
EuroVacc Foundation
NCT02235662 COMPLETED Phase I One-month Safety, PK, PD, and Acceptability Study of IVR Releasing TFV and LNG or TFV Alone
CONRAD
NCT00905489 COMPLETED A Phase I Multiple Dose Pharmacokinetic Study of Nevirapine Extended Release (XR) in HIV-1 Infected Children.
Boehringer Ingelheim
NCT02411435 COMPLETED Effect of Rifampin (RIF) on the Pharmacokinetics (PK) of Oral Cabotegravir (CAB) in Healthy Subjects
ViiV Healthcare
NCT02539576 COMPLETED Pharmacokinetics, Safety and Tolerability Study of Abacavir/ Dolutegravir/ Lamivudine Fixed-dose Combination Tablets in Healthy Japanese Subjects
ViiV Healthcare
NCT02269605 COMPLETED Bryostatin-1 Effect on HIV-1 Latency and Reservoir in HIV-1 Infected Patients Receiving Antiretroviral Treatment
Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
NCT02604004 COMPLETED Bioequivalence Study Between Lamivudine Formulations in the Form of Coated Tablet of 150 mg in Healthy Volunteers
Universidade Federal de Pernambuco
NCT02134886 TERMINATED Erlotinib Hydrochloride in Treating Non-Small Cell Lung Cancer That is Metastatic or Cannot be Removed by Surgery in Patients With HIV Infection
National Cancer Institute (NCI)
NCT02034838 COMPLETED Microboosting of Atazanavir 300 mg With 50 mg Versus 100mg Ritonavir Daily in HIV-infected Patients: a Pharmacokinetic Study
Ottawa Hospital Research Institute
NCT01363037 COMPLETED Safety and Pharmacokinetics of Dapivirine/Maraviroc Vaginal Ring
International Partnership for Microbicides, Inc.
NCT02164812 COMPLETED Study to Determine the Effect of Efavirenz on the ECG QTcF Interval in Healthy Subjects
Bristol-Myers Squibb
NCT00984971 COMPLETED Rectal Microbicide Safety and Acceptability Trial of Topically Applied Tenofovir Compared With Oral Tablet
CONRAD
NCT01705990 COMPLETED Safety and Immunogenicity Study of SeV-G(NP) HIV Vaccine Administered Intranasally and Ad35-GRIN HIV Vaccine Given Intramuscularly in Prime-Boost Regimens in HIV-Uninfected Volunteers
International AIDS Vaccine Initiative
NCT02202005 COMPLETED Multiple Dose BE Study With Nevirapine 400mg PR Tablets
Ratiopharm GmbH
NCT02109224 TERMINATED Ibrutinib in Treating Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma in Patients With HIV Infection
National Cancer Institute (NCI)
NCT01340196 COMPLETED Drug Drug Interaction of BI 201335 and Tenofovir
Boehringer Ingelheim
NCT01374802 COMPLETED Effect of Multiple Dosing With BI 201335 on the Pharmacokinetics of Darunavir Co-administered With Ritonavir in Healthy Male and Female Volunteers
Boehringer Ingelheim
NCT02345707 COMPLETED Relative Bioavailability Study of Phase III Tablet Formulation of Cabotegravir
ViiV Healthcare
NCT01749566 COMPLETED Exploring HIV Entry Blockade as a Pre-exposure Prophylaxis Strategy in Women
Emory University
NCT02159131 COMPLETED Study to Evaluate the Pharmacokinetics of an Oral Contraceptive Containing Levonorgestrel and Ethinyl Estradiol When Co-administered With GSK1265744 in Healthy Adult Female Subjects
ViiV Healthcare
NCT02489435 COMPLETED Clinical Trial of Safety and Pharmacokinetics of VM-1500 After Multiple Oral Administration in Healthy Volunteers
Viriom
NCT01283360 COMPLETED Microbicide Safety and Acceptability in Young Men
CONRAD
NCT01813162 COMPLETED In Vivo Drug Interaction Pharmacokinetic Study of Tenofovir 1% Gel and Three Commonly Used Vaginal Products
CONRAD
NCT01227590 COMPLETED Pharmacokinetic Interactions Between an Herbal Medicine (African Potato) and Antiretroviral Agents (Lopinavir/Ritonavir)
University of California, San Francisco
NCT01421368 COMPLETED Contraception and Menstrual Cycle Effect on Pharmacokinetics, Pharmacodynamics and Safety in Tenofovir Vaginal Gel Use
CONRAD
NCT01810315 COMPLETED Influence of Reproductive Cycle and Menopause on HIV-1 Infection and TFV Gel Activity
CONRAD
NCT00903084 COMPLETED Examining Hair to Determine Tenofovir Exposure
Public Health Foundation Enterprises, Inc.
NCT01694407 COMPLETED Safety, Pharmacokinetics, Pharmacodynamics, and Disintegration Time of Vaginal Tablets Containing Tenofovir and/or Emtricitabine
CONRAD
NCT01571466 COMPLETED A Study to Evaluate the Safety of the HIV-1 Vaccine MVA-B in Chronic HIV-1 Infected Patients Successfully Treated With HAART
Hospital Clinic of Barcelona
NCT01866046 COMPLETED Rapid HIV Testing and Counseling in High Risk Women in Shelters
The University of Akron
NCT01799954 COMPLETED Evaluating the Safety and Priming Response of an HIV Vaccine Regimen in Healthy, HIV-Uninfected Adults
HIV Vaccine Trials Network
NCT01044654 COMPLETED Phase 1 Dose Escalation Study of Autologous T-cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases in HIV-Infected Patients
Sangamo Therapeutics
NCT01719627 COMPLETED First Study to Evaluate the Capacity of Maraviroc Drug to Protect Against HIV Infection in Samples of Rectal Mucosa From Healthy Volunteers
Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia
NCT00632073 COMPLETED Effect of Vicriviroc on HIV Ribonucleic Acid (RNA) Levels in Cerebrospinal Fluid (Study P05241)
Merck Sharp & Dohme LLC
NCT01283100 WITHDRAWN A Drug Interaction Study Evaluating Plasma GSK2248761 and GSK1349572 Pharmacokinetics in Healthy Adult Subjects.
ViiV Healthcare
NCT01560221 COMPLETED Reducing Drug Use and HIV Risk in Drug-dependent Adults Arrested for Prostitution
Johns Hopkins University
NCT01723527 COMPLETED Diversion to Treatment for Injection Drug Users Arrested for Possession of Heroin
Johns Hopkins University
NCT02185300 COMPLETED Bioavailability Study of a Dolutegravir Dispersible Tablet and Effect of Different Types of Water on the Dispersible Tablet in Healthy Volunteers
ViiV Healthcare
NCT01841593 COMPLETED A Two Way Cross Over Pharmacokinetic Interaction Study Between Raltegravir and Amlodipine in Healthy Volunteers
St Stephens Aids Trust
NCT01837719 COMPLETED Bioequivalence Study of Individual Atazanavir and Cobicistat Compared With Atazanavir in Fixed-dose Combination With Cobicistat
Bristol-Myers Squibb
NCT02059031 COMPLETED A Study to Assess The Relative Bioavailability of New Tablet Formulations of GSK1265744 in Healthy Adult Subjects
ViiV Healthcare
NCT01562886 COMPLETED The Rilpivirine Cerebrospinal-fluid (CSF) Study
Imperial College London
NCT02027454 COMPLETED Study to Evaluate the Effect of GSK1265744 on Cardiac Conduction
ViiV Healthcare
NCT02082808 COMPLETED Study to Evaluate the Drug Interaction Between Dolutegravir (DTG) and Daclatasvir (DCV) in Healthy Adult Subjects
ViiV Healthcare
NCT02064374 COMPLETED Effect of Dolutegravir on Metformin Pharmacokinetics in Healthy Adult Subjects
ViiV Healthcare
NCT01827397 COMPLETED Safety & Immunogenicity of Immunisations With EN41-UGR7C HIV Vaccine
PX'Therapeutics
NCT01509144 COMPLETED EuroNeut41: Safety & Immunogenicity of Immunisations With HIV Vaccine
PX'Therapeutics
NCT01273103 WITHDRAWN A Study to Investigate the Recovery, Excretion, and Pharmacokinetics of 14C-GSK2248761 Administered as an Oral Suspension to Healthy Adult Subjects
ViiV Healthcare
NCT01575418 COMPLETED An Exploratory Rectal Safety Study of Three Tenofovir Gel Formulations
Ian McGowan
NCT01127464 COMPLETED DCVax Plus Poly ICLC in Healthy Volunteers
Rockefeller University
NCT00877591 COMPLETED Interaction of Buprenorphine With HIV Medications and Tuberculosis Medications
University of California, San Francisco
NCT00878306 COMPLETED Disulfiram Interactions With HIV Medications: Clinical Implications
University of California, San Francisco
NCT00879047 COMPLETED Interaction of Alcohol and Highly Active Antiretroviral Therapy (HAART) in HIV/AIDS and HIV/AIDS With Hepatitis C Virus (HCV) Co-Infection
University of California, San Francisco
NCT01151319 COMPLETED Safety and Immunogenicity Study of Three Candidate HIV-1 Vaccines, Administered in Combination to Healthy HIV-1 Uninfected Adults
University of Oxford
NCT01754116 COMPLETED A Randomized Study to Assess the Relative Bioavailability of New Formulations of GSK1265744 Long Acting Parental (LAP) in Healthy Adult Subjects
ViiV Healthcare
NCT01827540 COMPLETED Study of Dolutegravir (DTG) on PK of Cenicriviroc (CVC), and CVC on PK of DTG & on a Single Dose of Midazolam
Tobira Therapeutics, Inc.
NCT00910806 COMPLETED TMC207-TiDP13-C117: Interaction Study in Human Immunodeficiency Virus-type 1 (HIV-1) Infected Patients With Nevirapine (NVP)
Tibotec BVBA
NCT01009762 COMPLETED Immunization With HIV-1 Peptides in Adjuvant for Treatment of Patients With Chronic HIV-infection
Gitte Kronborg
NCT00890747 COMPLETED Sunitinib Malate in Treating HIV-Positive Patients With Cancer Receiving Antiretroviral Therapy
National Cancer Institute (NCI)
NCT01593046 COMPLETED A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Repeat Dose Administration of Long-Acting GSK1265744 and Long-Acting TMC278 Intramuscular and Subcutaneous Injections in Healthy Adult Subjects
ViiV Healthcare
NCT01967771 COMPLETED Effect of Carbamazepine on Dolutegravir Pharmacokinetics in Healthy Adult Subjects
ViiV Healthcare
NCT02012556 COMPLETED Pharmacokinetic and Pharmacodynamic Study of TH9507, a Growth Hormone-Releasing Factor Analog, in HIV Positive Patients
Theratechnologies
NCT01407497 COMPLETED Safety and Immunogenicity Study of a DNA Priming and MVA Boosting Strategy of HIV Vaccine
Instituto Nacional de Saúde, Mozambique
NCT00850837 COMPLETED Safety of Acidform Lubricant in HIV-Uninfected Women
National Institute of Allergy and Infectious Diseases (NIAID)
NCT01575405 COMPLETED A Study to Compare Three Different Formulations of Tenofovir 1% Gel When Administered Rectally
Ian McGowan
NCT01848340 COMPLETED An Study to Investigate the Recovery, Excretion, and Pharmacokinetics of 14C-GSK1265744 Administered as a Single Oral Dose and a Study to Describe the Pharmacokinetics of a Supratherapeutic Dose of GSK1265744 in Healthy Adult Subjects
ViiV Healthcare
NCT01424826 COMPLETED The Effect of Intermittent Rifampicin on Raltegravir
Helen Reynolds
NCT01956396 COMPLETED Evaluation of Safety and Efficacy of the PrePexTM Device for Rapid Scale up of Adult MC Programs in Zimbabwe
Ministry of Health and Child Welfare, Zimbabwe
NCT01546818 COMPLETED Safety and Immune Response Assessment Study of Killed-whole HIV-1 Vaccine (SAV001-H) in Chronic HIV-1 Infected Patients
Sumagen
NCT00961883 COMPLETED Safety of and Immune Response to Prime/Boost Vaccine Regimens in Healthy, HIV-1 Uninfected, Ad5 Seronegative Adults
HIV Vaccine Trials Network
NCT01130376 TERMINATED Novel Interventions in HIV-1 Infection
Imperial College London
NCT01268839 COMPLETED A Phase I, Open-label Trial to Explore the Pharmacokinetics, Safety and Tolerability of TMC278 (Rilpivirine) 25 mg Once Daily Following a 2-week Period Receiving Efavirenz, in Healthy Male and Female Volunteers
Tibotec, Inc
NCT01052883 COMPLETED TMC114-TiDP3-C182 - A Study to Compare the Oral Bioavailability of a 800 mg Prototype Tablet Formulation of Darunivar (DRV) to That of the 400 mg Commercial Tablet Formulation in the Presence of Low Dose Ritonavir, Under Fasted and Fed Conditions
Tibotec Pharmaceuticals, Ireland
NCT01496989 COMPLETED Safety and Immunogenicity Study of HIV-MAG Vaccine +/- IL-12 and Ad35-GRIN/ENV in HIV-uninfected Volunteers
International AIDS Vaccine Initiative
NCT01796431 COMPLETED Pharmacokinetics of Tenofovir and Tenofovir-diphosphate, Emtricitabine and Emtricitabine-triphosphate, and Rilpivirine Once Daily Over 14 Days Following Drug Intake Cessation in Healthy Volunteers
St Stephens Aids Trust
NCT01876966 COMPLETED Interaction Between Etravirine or Darunavir/Ritonavir and Artemether / Lumefantrine
Janssen Pharmaceutica N.V., Belgium
NCT01404572 COMPLETED Taste Assessment Study of 2 Atazanavir Powder Formulations in Healthy Subjects
Bristol-Myers Squibb
NCT01756131 COMPLETED A Single Dose Escalation Study to Investigate the Safety, Tolerability and Pharmacokinetics of Intramuscular and Subcutaneous Long Acting GSK1265744 in Healthy Subjects
ViiV Healthcare
NCT01762995 COMPLETED A Study to Evaluate the Effects of Calcium Carbonate and Ferrous Fumarate on Pharmacokinetics of Dolutegravir in Healthy Adult Subjects
ViiV Healthcare
NCT01818856 COMPLETED Pharmacokinetic Interactions Between Telaprevir and Un-boosted Atazanavir
Hospitales Universitarios Virgen del Rocío
NCT00679497 COMPLETED A Phase I Study of Modified Vaccinia Virus Ankara (MVA-B) in Healthy Volunteers at Low Risk of HIV Infection
Juan A. Arnaiz
NCT01264445 COMPLETED Safety and Immunogenicity Study of 2 Investigational Preventive HIV Vaccines
International AIDS Vaccine Initiative
NCT00902824 COMPLETED Safety and Immunogenicity of TBC-M4, a MVA HIV Vaccine Alone or in a Prime-Boost Regimen With ADVAX DNA HIV Vaccine
International AIDS Vaccine Initiative
NCT01355198 COMPLETED Role of HIV on Glutathione Synthesis and Oxidative Stress
Baylor College of Medicine
NCT01289951 COMPLETED Pharmacokinetic Study of Raltegravir in Human Immunodeficiency Virus/Hepatitis C Virus (HIV/VHC) Coinfected Patients With Advanced (Child-Pugh C) Hepatic Cirrhosis
Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
NCT00646776 COMPLETED Drug Interaction Study
Bristol-Myers Squibb
NCT01292174 COMPLETED Safety Study of Ibalizumab Subcutaneous Injection in Healthy Volunteers
TaiMed Biologics Inc.
NCT01215149 COMPLETED Safety and Immunogenicity Study of Ad26-ENVA and Ad35-ENV HIV Vaccines in Healthy HIV-uninfected Adults
International AIDS Vaccine Initiative
NCT01090648 COMPLETED TMC125HIV1083 - Swallowability of Uncoated 200 mg Etravirine Tablets in HIV-1 Infected Patients
Tibotec Pharmaceuticals, Ireland
NCT01285141 COMPLETED Reactogenicity and Immunogenicity of Cervico-vaginal CN54gp140-hsp70 Conjugate Vaccine
St George's, University of London
NCT01031589 COMPLETED TMC278-TiDP15-C158 - A Study to Examine the Safety, Tolerability and Pharmacokinetics of a Single Dose or Three Successive Doses of Intramuscularly (IM) Injected Long Acting Formulation of TMC278
Tibotec Pharmaceuticals, Ireland
NCT01082692 COMPLETED Study of PENNVAX™-B (Gag, Pol, Env) + Electroporation in HIV-1 Infected Adult Participants
Inovio Pharmaceuticals
NCT00833482 COMPLETED Drug Interactions Between Voriconazole and Atazanavir Coadministered as Atazanavir/Ritonavir in Healthy Participants
Bristol-Myers Squibb
NCT01170741 COMPLETED Computer-Assisted Tailored Cue-card Health [CATCH] Study
RTI International
NCT01622790 COMPLETED Evaluation of the Bioequivalence of a Combined Formulated Tablet
ViiV Healthcare
NCT01467531 COMPLETED A Study to Evaluate the Pharmacokinetics and Safety of GSK1265744 and Rilpivirine and Dolutegravir and Rilpivirine in Healthy Adult Subjects
ViiV Healthcare
NCT01071031 COMPLETED HIV Vaccine Study in HIV Positive Patients
PepTcell Limited
NCT01336829 COMPLETED TMC125IFD1001 - Drug-Drug Interaction of Etravirine With Telaprevir and TMC278 With Telaprevir.
Tibotec Pharmaceuticals, Ireland
NCT00828529 COMPLETED TMC207-TiDP13-C110: Interaction Study With Lopinavir/Ritonavir in Healthy Volunteer
Tibotec BVBA
NCT01348516 COMPLETED Single Ascending Dose (SAD)/Multiple Ascending Dose(MAD) Safety/Pharmacokinetic (PK) Study of KM-023
Kainos Medicine Inc.
NCT01084343 COMPLETED Investigation of the Safety of an HIV-1 Vaccine Given Intra-muscularly and Intra-nasally to Healthy Female Subjects
Mymetics Corporation
NCT01214993 COMPLETED A Phase 1, Open Label, Placebo-Controlled Study to Evaluate the Effect of GSK1349572 on Iohexol and Para-Aminohippurate Clearance in Healthy Subjects
ViiV Healthcare
NCT01597648 COMPLETED A Study to Evaluate the Bioequivalence of a Combined Formulated Tablet Compared With Maraviroc and Combivir™
GlaxoSmithKline
NCT01498861 COMPLETED Drug Interaction Study Between Dolutegravir and an Oral Contraceptive Containing Norgestimate and Ethinylestradiol
ViiV Healthcare
NCT01353716 COMPLETED Dolutegravir Renal Impairment Study
ViiV Healthcare
NCT00851383 COMPLETED A Trial to Evaluate Ad35-GRIN/ENV HIV Vaccine in Healthy Adult Volunteers
International AIDS Vaccine Initiative
NCT01467518 COMPLETED Methadone-Dolutegravir (DTG - GSK1349572) Drug Interaction Study.
ViiV Healthcare
NCT00812318 COMPLETED Healthy Volunteer Study To Assess The Bioavailability of GSK1265744 When Administered Orally Either When Fasted or Following a Meal.
ViiV Healthcare
NCT00757250 TERMINATED Safety Study of TXA127 to Elevate CD4+ T-Lymphocyte Counts in HIV-Infected Patients on Stable HAART Therapy
US Biotest, Inc.
NCT01320176 COMPLETED Study to Evaluate the Dosage and Safety of Two Intramuscular Injections of an Investigational Clade B HIV Vaccine
Institut Pasteur
NCT01276990 WITHDRAWN Safety and Pharmacokinetics of Multiple Rising Oral Doses of BI 224436 in Healthy Male Volunteers.
Boehringer Ingelheim
NCT00982579 COMPLETED Safety and Immunogenicity Study of Candidate HIV-1 Vaccine Given to Healthy Infants Born to HIV-1/2-uninfected Mothers
Medical Research Council
NCT01403792 COMPLETED A Safety Study Of A Single Vaginal Administration Of P2G12 Antibody In Healthy Female Subjects
University of Surrey
NCT01425099 COMPLETED Drug Interaction Study Between Dolutegravir and Prednisone
ViiV Healthcare
NCT01382238 COMPLETED Relative Bioavailability Study of a Pediatric Granule Formulation of Dolutegravir
ViiV Healthcare
NCT01242579 WITHDRAWN A Safety and Pharmacokinetic Study for Dapivirine and Maraviroc Gel in Belgium
International Partnership for Microbicides, Inc.
NCT01423357 COMPLETED Targeting Interventions at Venues Where Risk of HIV Transmission is High
University of Zambia
NCT01366547 COMPLETED Relative Bioavailability Study of Two New Dolutegravir/Abacavir/Lamivudine Fixed Dose Combination Tablets
ViiV Healthcare
NCT01140126 COMPLETED Study to Evaluate Safety and Pharmacokinetics of UB-421 Antibody in HIV-1 Infected Adults
United Biomedical
NCT01288755 COMPLETED TMC278-TiDP6-C153 - A Study in Healthy Volunteers Investigating the Pharmacokinetic Interaction Between TMC278 and Raltegravir
Tibotec Pharmaceuticals, Ireland
NCT01332565 COMPLETED A Study to Investigate the Pharmacokinetics, Safety and Tolerability of GSK1349572 (Dolutegravir, DTG) in Healthy Japanese Subjects
ViiV Healthcare
NCT00792519 COMPLETED Cognitive Behavioral Treatment to Reduce Alcohol Use Among HIV-Infected Kenyans
Brown University
NCT00740389 COMPLETED TMC125-TiDP2-C187: A Phase I, Open-label Trial to Investigate the Pharmacokinetic Interaction Between TMC125 and Two Antifungal Agents (Fluconazole and Voriconazole), All at Steady-state in Healthy Subjects.
Tibotec Pharmaceuticals, Ireland
NCT00744887 COMPLETED TMC114-TiDP3-C181: Study to Assess the Pharmacokinetics of Darunavir (DRV) With Different Doses of Ritonavir in Healthy Volunteers.
Tibotec Pharmaceuticals, Ireland
NCT00767117 COMPLETED TMC125-TiDP2-C197: A Phase I Trial to Investigate the Pharmacokinetic Interaction Between Lopinavir/Ritonavir and TMC125 Both at Steady-state in Healthy Volunteers.
Tibotec Pharmaceuticals, Ireland
NCT00812292 COMPLETED TMC278-TiDP38-C145: A Bioavailability Study in Healthy Adult Volunteers to Evaluate 3 Pediatric Formulations of TMC278 (a Solution, a Suspension, and Granules) Compared to an Adult Tablet Formulation
Tibotec Pharmaceuticals, Ireland
NCT00828815 COMPLETED TMC125-TiDP2-C188: A Phase I, Open-label Trial to Investigate the Pharmacokinetic Effect of Multiple-dose TMC125 on Buprenorphine and Norbuprenorphine Administered in HIV-negative Patients on Stable Buprenorphine/Naloxone Maintenance Therapy.
Tibotec Pharmaceuticals, Ireland
NCT00775294 COMPLETED Study in Healthy Males to Measure Maraviroc in Blood, Saliva, Seminal Fluid, and Rectal Tissue
University of North Carolina, Chapel Hill
NCT00855088 COMPLETED Study in Healthy Males to Measure Darunavir and Etravirine in Blood, Seminal Fluid, and Rectal Tissue
University of North Carolina, Chapel Hill
NCT01056874 COMPLETED Effect Of Maraviroc On The Pharmacokinetics Of Digoxin
ViiV Healthcare
NCT00871234 COMPLETED Effects of Etravirine on Endothelial Function in HIV-uninfected Adults: A Pilot Study
Indiana University
NCT00828789 COMPLETED VX-950-TiDP24-C134: Drug-drug Interaction Trial Between Combination of Efavirenz and Tenofovir Disoproxil Fumarate and Different Dosages of Telaprevir on Healthy Volunteer
Tibotec BVBA
NCT00775125 COMPLETED VX-950-TiDP24-C124: A Phase I Trial to Investigate the Potential Pharmacokinetic Interactions Between Telaprevir and Darunavir/Ritonavir and Between Telaprevir and Fosamprenavir/Ritonavir at Steady-state.
Tibotec BVBA
NCT00993811 COMPLETED The Shang Ring: A Novel Male Circumcision Device for HIV Prevention
Weill Medical College of Cornell University
NCT01231451 WITHDRAWN Depot Contraception With and Without Lopinavir/Ritonavir
St Stephens Aids Trust
NCT00821535 COMPLETED Investigation Of Safety And Pharmacokinetics Following A Single Oral Dose Of 300 Mg Maraviroc In Healthy Male Japanese Volunteers
ViiV Healthcare
NCT01138072 COMPLETED A Drug Interaction Study Between Simvastatin, Atorvastatin, Rosuvastatin, and GSK2248761 in Healthy Subjects.
GlaxoSmithKline
NCT00920088 COMPLETED Drug Interaction Study of Darunavir/Ritonavir and Lopinavir/Ritonavir on GSK2248761 PK and CYP450 Probe Drugs
GlaxoSmithKline
NCT00743470 TERMINATED A Bioavailability Study of Rifabutin and Lopinavir/Ritonavir in Healthy Adult Subjects
Abbott
NCT01108926 COMPLETED PK of Tenofovir, Emtricitabine and Efavirenz in Healthy Volunteers
St Stephens Aids Trust
NCT00741741 TERMINATED TMC278-TiDP15-C150: Trial to Examine Safety, Tolerability and Plasma Pharmacokinetics of Multiple Doses of TMC278LA.
Tibotec Pharmaceuticals, Ireland
NCT00659191 COMPLETED A Healthy Volunteer And Patient Study To Assess The Safety, Tolerability And Pharmacokinetics Of GSK1265744
GlaxoSmithKline
NCT01144676 COMPLETED A Safety Study to Assess the Delivery of Dapivirine From a Matrix Vaginal Ring
International Partnership for Microbicides, Inc.
NCT00774735 COMPLETED GSK1349572 Drug Interaction Study With Protease Inhibitors
GlaxoSmithKline
NCT00920296 COMPLETED DDI Study of Etravirine and GSK1265744
GlaxoSmithKline
NCT01073761 COMPLETED Atazanavir/Ritonavir and Darunavir/Ritonavir PK Tail Study
St Stephens Aids Trust
NCT00771823 COMPLETED Maraviroc 300 mg Twice Daily in HIV Negative Male Volunteers
St Stephens Aids Trust
NCT00772551 COMPLETED Raltegravir and Ezetimibe PK Study
St Stephens Aids Trust
NCT01001247 COMPLETED TMC278-TiDP6-C154: Evaluation of the Possible Influence of Omeprazole Intake - and the pH Increase in the Stomach Triggered by Omeprazole Intake - on the Blood Levels of TMC278 in Healthy Volunteers
Tibotec Pharmaceuticals, Ireland
NCT00623259 COMPLETED Phase I Safety Study of a Recombinant MVA HIV Multiantigen Vaccine in HIV-infected Subjects
Bavarian Nordic
NCT00736905 COMPLETED TMC278-TiDP6-C130: Pharmacokinetics, Safety and Tolerability of TMC278 in Subjects With Mildly or Moderately Impaired Hepatic Function.
Tibotec Pharmaceuticals, Ireland
NCT00739622 COMPLETED TMC278-TiDP6-C136: Effect of TMC278 on Ethinylestradiol and Norethindrone in Healthy Women.
Tibotec Pharmaceuticals, Ireland
NCT00838760 COMPLETED PEPI-TiDP23-C103: First-in-Human Study to Examine the Safety, Tolerability, and Plasma Pharmacokinetics of Increasing Single and Repeated Oral Doses of TMC558445 and of a Combined Single Day Dosing of Oral TMC558445 and Oral TMC310911 and Also Oral Darunavir
Tibotec Pharmaceuticals, Ireland
NCT00854204 COMPLETED Innovation-TiFP4-C101: A Study to Evaluate the Pharmacokinetics of TMC114 and TMC41629 After a Single Oral Dose of 2 Controlled-release Coformulations as Compared to an Immediate-release Coformulation of TMC114/TMC41629
Tibotec Pharmaceuticals, Ireland
NCT00744770 COMPLETED TMC278-TiDP6-C121: Drug-drug Interaction Trial to Investigate the Potential Interaction Between TMC278 25 mg Daily and Methadone, at Steady State.
Tibotec Pharmaceuticals, Ireland
NCT01045317 COMPLETED A Study To Investigate The Clearance Of PF-04776548 From The Body Following A Very Low (Micro) Dose Of The Compound Using A Low Level Of Radiotracer To Help Quantify Expected Low Concentrations Of PF-04776548 In The Body
Pfizer
NCT01027182 COMPLETED Comparison of Concentration-time Course of Plasma and Intracellular Raltegravir in Healthy Volunteers
Changi General Hospital
NCT01047995 COMPLETED Pharmacokinetics (PK) Study of Once Daily Darunavir/Ritonavir and Twice and Once Daily Raltegravir in HIV-infected Subjects
St Stephens Aids Trust
NCT00765271 COMPLETED Abacavir Pharmacokinetic Study in the Absence/Presence of Darunavir/Ritonavir or Raltegravir in HIV-infected Subjects
St Stephens Aids Trust