Hypertension Clinical Trial Landscape
Data updated: May 20, 2026
2,131 clinical trials tracked since 2008
Hypertension, or high blood pressure, is a common condition in which the force of the blood against artery walls is too high, potentially leading to serious health problems. As of 2024, the clinical trial landscape for hypertension is active, with 2,119 trials registered since 2008, and 306 trials currently active. These active trials span all phases of clinical development, with 71 in Phase 1, 107 in Phase 2, 89 in Phase 3, and 73 in Phase 4. This spread suggests continued interest in both novel therapies and the long-term effects of existing treatments. Boryung Pharmaceutical Co., Ltd is the leading industry sponsor with 6 active trials, followed by Merck, and Addpharma Inc., each sponsoring 5 active trials. Actelion and Eli Lilly are also notable sponsors, each with 4 active trials currently underway.
307 active
/
2131 total (since 2008)
75
Phase 1 Active
459 total
106
Phase 2 Active
654 total
88
Phase 3 Active
622 total
72
Phase 4 Active
553 total
Top Industry Sponsors
Sorted by active Active Done Failed
Boryung Pharmaceutical Co., Ltd 6 53 0
Addpharma Inc. 6 10 0
Merck 5 28 3
Actelion 4 31 14
Eli Lilly 4 3 1
+ 10 more sponsors — see full table below
Featured Phase 3 Trials
NCT07245680 RECRUITING
COMMODITIES Trial: Initial Dual Oral Therapy vs Monotherapy in PAH With Cardiovascular Comorbidities
Assistance Publique - Hôpitaux de Paris n=186
NCT07064473 RECRUITING
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
Boehringer Ingelheim n=11,800
NCT06948422 RECRUITING
A Master Protocol for Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight: (ATTAIN-Hypertension Screening)
Eli Lilly and Company n=974
NCT02562235 ACTIVE NOT RECRUITING
Riociguat in Children With Pulmonary Arterial Hypertension (PAH)
Bayer n=24
NCT07365332 RECRUITING
An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH)
Inhibikase Therapeutics n=486
+ 617 more Phase 3 trials — see full database below
Hypertension — Trials Started by Year (last 10 years)
2016 95
2017 85
2018 91
2019 90
2020 63
2021 92
2022 84
2023 81
2024 106
2025 105
2026 67
TheraRadar.com
Full Trial Database
Complete sponsor table, every trial across all phases, plus competitive analytics. Sortable, filterable, exportable for Pro users.
Top Sponsors (all-time)
Boryung Pharmaceutical Co., Ltd 59
Addpharma Inc. 16
Merck 36
Actelion 49
Eli Lilly 8
Insmed Incorporated 8
Novartis 96
Liquidia Technologies, Inc. 5
Tenax Therapeutics, Inc. 4
Qilu Pharmaceutical Co., Ltd. 3
Active Trials by Phase
Phase 1 75
Phase 2 106
Phase 3 88
Phase 4 72
Enrollment Size Distribution
1-50 817
51-200 676
201-500 329
501-1k 127
1k+ 60
All Industry Sponsors
Sorted by active Active Done Failed
Boryung Pharmaceutical Co., Ltd 6 53 0
Addpharma Inc. 6 10 0
Merck 5 28 3
Actelion 4 31 14
Eli Lilly 4 3 1
Insmed Incorporated 4 3 1
Novartis 3 80 13
Liquidia Technologies, Inc. 3 1 1
Tenax Therapeutics, Inc. 3 1 0
Qilu Pharmaceutical Co., Ltd. 3 0 0
SpyGlass Pharma, Inc. 3 0 0
United Therapeutics 2 21 19
Chong Kun Dang Pharmaceutical 2 38 1
AbbVie 2 34 1
Pfizer 2 2 9
NCT07245680 RECRUITING
COMMODITIES Trial: Initial Dual Oral Therapy vs Monotherapy in PAH With Cardiovascular Comorbidities
Assistance Publique - Hôpitaux de Paris n=186
NCT07064473 RECRUITING
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
Boehringer Ingelheim n=11,800
NCT06948422 RECRUITING
A Master Protocol for Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight: (ATTAIN-Hypertension Screening)
Eli Lilly and Company n=974
NCT02562235 ACTIVE NOT RECRUITING
Riociguat in Children With Pulmonary Arterial Hypertension (PAH)
Bayer n=24
NCT07365332 RECRUITING
An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH)
Inhibikase Therapeutics n=486
NCT07218029 RECRUITING
A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)
Merck Sharp & Dohme LLC n=815
NCT04175600 ACTIVE NOT RECRUITING
A Study of Selexipag as Add-On Treatment to Standard of Care in Children With Pulmonary Arterial Hypertension
Actelion n=138
NCT05179876 RECRUITING
A Study Providing Treatment Access in Participants With Pulmonary Hypertension Completing a Parent Study and Having no Other Option
Actelion n=280
NCT07179380 RECRUITING
Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
Insmed Incorporated n=344
NCT07562477 NOT YET RECRUITING
Efficacy of Remote Ischemic Conditioning for Hypertension in High-Altitude Immigrant Populations
Capital Medical University n=184
NCT06274801 ACTIVE NOT RECRUITING
Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)
GB002, Inc. n=316
NCT07552389 RECRUITING
Clinical Trial to Evaluate the Efficacy and Safety of Monotherapy Group of HL1113R1 or HL1113R2 Versus HL1113 (Fixed Dose Combination) in Patients With Essential Hypertension and Type II Diabetes Mellitus
Hanlim Pharm. Co., Ltd. n=228
NCT06952530 RECRUITING
A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL2
Eli Lilly and Company n=487
NCT06948435 RECRUITING
A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL1
Eli Lilly and Company n=487
NCT07181109 RECRUITING
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
Alnylam Pharmaceuticals n=11,000
NCT07528027 NOT YET RECRUITING
Phase III Study of HRS-7535 for Hypertension With Overweight or Obesity
Shandong Suncadia Medicine Co., Ltd. n=648
NCT05649748 ACTIVE NOT RECRUITING
An Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) for Pulmonary Arterial Hypertension (PAH)
Insmed Incorporated n=91
NCT04273945 ACTIVE NOT RECRUITING
Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension
Actelion n=935
NCT04971720 RECRUITING
PRECISION-BP: Precision Chronopharamacotherapy Targeting NP-RAAS-BP Rhythm Axis
University of Alabama at Birmingham n=160
NCT06683040 ACTIVE NOT RECRUITING
Evaluation of the Efficacy and Safety of Oxacom® in Patients With Pulmonary Arterial Hypertension
National Medical Research Center for Cardiology, Ministry of Health of Russian Federation n=260
NCT07080229 RECRUITING
Intranasal Dexmedetomidine on Blood Pressure in Elderly Hypertensive Patients Undergoing Cataract Surgery
Suez Canal University n=126
NCT07354516 RECRUITING
Study of QLS-111-FDC in Open-Angle Glaucoma or Ocular Hypertension
Qlaris Bio, Inc. n=60
NCT04691154 ACTIVE NOT RECRUITING
A Phase 3 Study to Evaluate the Safety and Tolerability of L606 in Subjects With PAH or PH-ILD
Liquidia Technologies, Inc. n=28
NCT07436689 ENROLLING BY INVITATION
Long-Term Open-Label Extension Study of Oral Levosimendan
Tenax Therapeutics, Inc. n=800
NCT07481981 NOT YET RECRUITING
A Study to Evaluate the Efficacy and Safety of Once Daily Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Arterial Hypertension (PAH)
Insmed Incorporated n=344
NCT07288398 RECRUITING
LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
Tenax Therapeutics, Inc. n=540
NCT07462260 RECRUITING
Sildinafil in Pulmonary Hypertension-Rheumatic Chronic Valvular Disease(RCT)
Sindh Institute of Cardiovascular Diseases n=100
NCT07223502 RECRUITING
A Study Comparing the Clinical Benefit of Finerenone Versus a Fixed Dose Combination (FDC) of Extended-Release Torsemide and Spironolactone in Patients With Hypertension and Chronic Kidney Disease
Sarfez Pharmaceuticals, Inc. n=30
NCT03683186 ENROLLING BY INVITATION
A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension
United Therapeutics n=1,000
NCT05983250 RECRUITING
LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF
Tenax Therapeutics, Inc. n=230
NCT05968430 ACTIVE NOT RECRUITING
Open-Label Extension (OLE) Study to Assess Safety, Efficacy, and Tolerability of Lorundrostat in Subjects With Hypertension
Mineralys Therapeutics Inc. n=1,076
NCT05551104 RECRUITING
Safest Choice of Antihypertensive Regimen for Postpartum Hypertension
Loma Linda University n=500
NCT07335211 RECRUITING
Efficacy and Safety of HUC3-637 in Patients With Primary Open Angle Glaucoma or Ocular Hypertension
Huons Co., Ltd. n=206
NCT05844462 RECRUITING
Tadalafil for Severe Pulmonary Hypertension Due to Chronic Obstructive Pulmonary Disease
Assistance Publique - Hôpitaux de Paris n=200
NCT06804161 RECRUITING
SGLT2 Inhibition for Cardiovascular Endpoint Reduction in Hypertension
Prof. Dr. med. Ingo Eitel n=3,000
NCT07285655 RECRUITING
A Phase 3 Study to Evaluate the Safety and Efficacy L606 in Participants With PH-ILD
Liquidia Technologies, Inc. n=344
NCT06643819 RECRUITING
Phase 3 Trial to Evaluate the Efficacy and Safety of CKD-202A
Chong Kun Dang Pharmaceutical n=324
NCT05732727 RECRUITING
Intensification of Blood Pressure Lowering Therapeutics Based on Diuretics Versus Usual Management for Uncontrolled Hypertension IN Patients With Moderate to Severe Chronic Kidney Disease
University Hospital, Tours n=720
NCT07030101 NOT YET RECRUITING
A Study to Investigate Efficacy and Safety of a TCA108 in Participants ≥18 Years With Uncontrolled Hypertension
EMS n=400
NCT07232966 NOT YET RECRUITING
Perirenal Adipose Tissue Modification Therapy for Resistant Hypertension
Yan Li n=220
NCT07234032 NOT YET RECRUITING
An Open-Label Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
Insmed Incorporated n=344
NCT07231900 NOT YET RECRUITING
Sodium Bicarbonate in Intra-dialytic Hypertension in Chronic Hemodialysis Patients
Assaf-Harofeh Medical Center n=40
NCT07222852 NOT YET RECRUITING
Cardiovascular Protection After Preeclampsia With Enalapril
Women and Infants Hospital of Rhode Island n=60
NCT04298034 ACTIVE NOT RECRUITING
Preeclampsia Postpartum Antihypertensive Treatment
Medical College of Wisconsin n=300
NCT07218796 RECRUITING
Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhone)
SpyGlass Pharma, Inc. n=400
NCT07218783 RECRUITING
Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhine)
SpyGlass Pharma, Inc. n=400
NCT04967989 RECRUITING
Clarifying the Optimal Application of SLT Therapy Trial
University of Pittsburgh n=790
NCT07187206 RECRUITING
Safety and Efficacy of FETO in CDH Phase III
Children's Hospital Medical Center, Cincinnati n=75
NCT06647745 RECRUITING
A Randomized, Double-blind, Multi-center, Active-controlled, Phase 3 Clinical Trial to Evaluate the Efficacy and Safety of Combination Therapy of THP-00101, THP-00102, and THP-00103 in Subjects With T2DM and Essential Hypertension
THPharm Corp. n=221
NCT06643130 RECRUITING
Evaluate the Efficacy and Safety of Co-administration of JW0104+C2402 in Patients With Hypertension and Dyslipidemia
JW Pharmaceutical n=162
NCT05473520 RECRUITING
Doxycycline Host-directed Therapy to Improve Lung Function and Decrease Tissue Destruction in Pulmonary Tuberculosis
National University Hospital, Singapore n=150
NCT04356326 RECRUITING
Chronic Hypertension and Acetyl Salicylic Acid in Pregnancy
Centre Hospitalier Intercommunal Creteil n=500
NCT03891446 ACTIVE NOT RECRUITING
Long-term Safety and Efficacy Extension Trial of Bimatoprost SR
AbbVie n=455
NCT05852054 ACTIVE NOT RECRUITING
Supporting Transitions to Primary Care Among Under-resourced, Postpartum Women (STEP-UP)
Northwestern University n=1,500
NCT06150560 RECRUITING
A Study of Angiotensin-II Receptor Blocker on Cardiovascular Remodeling (VALUE Trial)
Mayo Clinic n=120
NCT06174766 RECRUITING
A Study to Evaluate Efficacy and Safety of HGP2102 in Essential Hypertension Patients
Hanmi Pharmaceutical Company Limited n=324
NCT07008365 RECRUITING
The Role of intraABDOminal Pressure and Point Of Care UltraSound to Guide Decongestive Therapy in Heart Failure
Instituto de Investigación Sanitaria Aragón n=168
NCT06263816 NOT YET RECRUITING
Effect of Long-term Carvedilol to Prevent Decompensation or Death in Patients With Asymptomatic Child-Pugh A5 to B8 Cirrhosis and Clinically Significant Portal Hypertension: a Multicenter Double-blind Randomized Control Trial
University Hospital, Tours n=290
NCT06350032 RECRUITING
Investigational Trial to Evaluate Safety and Tolerability of Treprostinil in Children Diagnosed With PAH
AOP Orphan Pharmaceuticals AG n=20
NCT04007289 ACTIVE NOT RECRUITING
Apixaban for Intrahepatic Non Cirrhotic Portal Hypertension
Assistance Publique - Hôpitaux de Paris n=166
NCT06646354 ENROLLING BY INVITATION
To Evaluate the Efficacy and Safety of Co-administrated HODO-2224-1 and HODO-2224-2 in Patients With Essential Hypertension and Primary Hypercholesterolemia
Hyundai Pharm n=125
NCT06922240 RECRUITING
Riociguat-Discontinue Effects on Right HEART in CTEPH (RED-HEART)
Suqiao Yang n=68
NCT06863987 ENROLLING BY INVITATION
A Phase III Clinical Study of Valsartan Oral Solution for the Treatment of Hypertension in Children and Adolescents
Shandong New Time Pharmaceutical Co., LTD n=342
NCT06666855 ACTIVE NOT RECRUITING
A Phase III Study in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension in China
Santen Pharmaceutical Co., Ltd. n=345
NCT06852079 RECRUITING
Safety & Efficacy of Qurs e Fishar in Mild to Moderate Hypertensive Patients in Pakistan
Abdul Bari n=119
NCT04062565 RECRUITING
Trial to Evaluate Parenteral Treprostinil and Riociguat on Right Ventriculo-vascular Coupling and Morphology in Those With Advanced PAH
University of Arizona n=20
NCT05460416 RECRUITING
Treatment Preventive for Pre-eclampsia by Acetylsalicylic Acid in Women Who Underwent Frozen Embryo Transfer
Centre Hospitalier Universitaire de Liege n=276
NCT05470205 RECRUITING
Noninvasive Subharmonic Aided Pressure Estimation of Portal Hypertension; Renewal
Thomas Jefferson University n=660
NCT06441630 RECRUITING
A Study to Evaluate the Efficacy and Safety of Co-administration of AD-227A and AD-227B
Addpharma Inc. n=251
NCT03992755 ACTIVE NOT RECRUITING
Extension Study for Participants in LIQ861 Trials to Evaluate the Long-term Safety of Dry Powder Inhalation of Treprostinil
Liquidia Technologies, Inc. n=92
NCT06771245 NOT YET RECRUITING
A Phase III Clinical Trial Evaluating the Efficacy and Safety of Valsartan/Levamlodipine (SYH9056) Tablets In Hypertensive Patients
CSPC ZhongQi Pharmaceutical Technology Co., Ltd. n=606
NCT06716970 NOT YET RECRUITING
QR12000 Compound Tablets in Patients with Moderate to Severe Essential Hypertension
Wuhan Createrna Science and Technology Co., Ltd n=810
NCT06608472 NOT YET RECRUITING
Fixed-dose Combination of an Angiotensin Receptor Blocker and Thiazide Diuretic for Essential Hypertension
Eurofarma Laboratorios S.A. n=292
NCT06696248 NOT YET RECRUITING
Carvedilol and Alverine in Portal Hypertension
Shanghai Changzheng Hospital n=30
NCT05636826 RECRUITING
Olive Leaf Extracts in the Control of Hypertension
University of Monastir n=500
NCT05824923 RECRUITING
A Trial to Evaluate the Safety and Efficacy of Pulmonary Artery Denervation for the Treatment of Pulmonary Hypertension Associated With Left Heart Failure
Pulnovo Medical (Wuxi) Co., Ltd. n=264
NCT06473493 NOT YET RECRUITING
The Safety and Efficacy of Alverine in the Treatment of Cirrhotic Portal Hypertension
Shanghai Changzheng Hospital n=30
NCT06470386 NOT YET RECRUITING
The Efficacy and Safety of Alverine in the Treatment of Portal Hypertension in Patients With Liver Cirrhosis
Shanghai Changzheng Hospital n=178
NCT06434753 RECRUITING
Zinc Supplementation to Improve Prognosis in Patients With Compensated Advanced Chronic Liver Disease.
Hospital Universitari Vall d'Hebron Research Institute n=300
NCT06061718 ACTIVE NOT RECRUITING
Travoprost Intraocular Implant in Conjunction With Cataract Surgery
Glaukos Corporation n=60
NCT06416865 RECRUITING
Efficacy and Safety of AJU-C52 in Essential Hypertension Patients
AJU Pharm Co., Ltd. n=190
NCT06220773 RECRUITING
A Study to Evaluate the Efficacy and Safety of BR1019A and BR1019B Combination Therapy
Boryung Pharmaceutical Co., Ltd n=276
NCT06348576 RECRUITING
Phase III Study to Evaluate the Efficacy and Safety of AD-209
Addpharma Inc. n=280
NCT05401357 RECRUITING
Bioequivalence Study With Clinical Endpoint Comparing Bimatoprost Ophthalmic Solution 0.01% and LUMIGAN® in the Treatment of Chronic Open-Angle Glaucoma or Ocular Hypertension in Both Eyes.
Amneal Pharmaceuticals, LLC n=168
NCT06682000 COMPLETED
Efficacy and Safety of DWC202404 and DWC202314 in Patients With Hypertension
Daewoong Pharmaceutical Co. LTD. n=192
NCT07564726 COMPLETED
Efficacy and Safety of Ezetimibe/Rosuvastatin and Amlodipine Patients With High Blood Pressure and High Cholesterol
Celltrion Pharm, Inc. n=163
NCT05167825 COMPLETED
A Study of Macitentan in Japanese Pediatric Participants With Pulmonary Arterial Hypertension
Janssen Pharmaceutical K.K. n=7
NCT06728514 COMPLETED
Comparative Study of USG Guided ESPB vs USG Guided PVB For Post-op Analgesia In Patient's After Open Renal Surgeries
Sahiwal medical college sahiwal n=72
NCT06153693 COMPLETED
Efficacy and Safety of Lorundrostat in Subjects With Uncontrolled and Resistant Hypertension
Mineralys Therapeutics Inc. n=1,083
NCT05643508 COMPLETED
A Clinical Trial to Evaluate the Efficacy and Safety of Co-administration of DWC202206 and DWC202207 in Patients With Concomitant Hypertension and Hyperlipidemia
Daewoong Pharmaceutical Co. LTD. n=214
NCT07083765 SUSPENDED
Renal Artery Denervation Assessment Without Antihypertensive Medication Regimen (RADAR)
Ablative Solutions, Inc. n=142
NCT07557680 COMPLETED
Dexmedetomidine in Attenuation of Haemodynamic Response to Laryngoscopy in Controlled Hypertensive Patients
Sindh Institute of Urology and Transplantation n=70
NCT05934526 COMPLETED
Efficacy and Safety of Seralutinib in Adult Subjects With PAH (PROSERA)
GB002, Inc. n=390
NCT04811092 TERMINATED
Study of Sotatercept in Newly Diagnosed Intermediate- and High-Risk PAH Participants (MK-7962-005/A011-13)
Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ USA n=321
NCT05649722 COMPLETED
An Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) for Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
Insmed Incorporated n=31
NCT06344104 COMPLETED
A Study to Investigate the Efficacy and Safety of Baxdrostat in Participants With Uncontrolled Hypertension on Two or More Medications Including Participants With Resistant Hypertension
AstraZeneca n=326
NCT07082816 COMPLETED
Reformulated PG324 Ophthalmic Solution for Intraocular Pressure Reduction
Alcon Research n=489
NCT03626688 COMPLETED
A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients
United Therapeutics n=687
NCT03794583 TERMINATED
Inhaled Treprostinil in Participants With Pulmonary Hypertension Due to Chronic Obstructive Pulmonary Disease (PH-COPD)
United Therapeutics n=41
NCT07181382 SUSPENDED
Efficacy and Safety of Seralutinib in Adult Subjects With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
GB002, Inc. n=480
NCT06671392 COMPLETED
A Phase III Study to Efficacy and Safety of DWC202405/DWC202313 and DWC202314 in Patients With Hypertension
Daewoong Pharmaceutical Co. LTD. n=198
NCT02932410 COMPLETED
A Study to Assess Whether Macitentan Delays Disease Progression in Children With Pulmonary Arterial Hypertension (PAH)
Actelion n=165
NCT07448506 COMPLETED
PHASE III, RANDOMIZED, ACTIVE-COMPARATOR CONTROLLED CLINICAL TRIAL TO EVALUATE THE EFFICACY AND SAFETY OF NIFEDIPINE 30MG EXTENDED-RELEASE IN ADULT PATIENTS DIAGNOSED WITH MILD OR MODERATE HYPERTENSION IN COLOMBIA.
Laboratorios Richmond S.A.C.I.F. n=50
NCT05818137 COMPLETED
A Study of Sotatercept in Japanese Pulmonary Arterial Hypertension (PAH) Participants (MK-7962-020)
Merck Sharp & Dohme LLC n=46
NCT04896008 COMPLETED
A Study of Sotatercept in Participants With PAH WHO FC III or FC IV at High Risk of Mortality (MK-7962-006/ZENITH)
Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ USA n=173
NCT04039464 COMPLETED
Mono vs. Dual Therapy for Pediatric Pulmonary Arterial Hypertension
Johns Hopkins University n=28
NCT06168409 COMPLETED
A Study to Investigate the Effect of Baxdrostat on Ambulatory Blood Pressure in Participants With Resistant Hypertension
AstraZeneca n=218
NCT07385040 COMPLETED
Comparison of IV Lignocain and IV Dexmedetomidine for Attenuation of Laryngoscopic Stress Response to Direct Laryngoscopy
Shaheed Mohtarma Benazir Bhutto Institue of Trauma n=62
NCT06236061 COMPLETED
Study of Efficacy and Safety of LCZ696/Amlodipine in Grade 1 and 2 Hypertension Patients Uncontrolled by LCZ696 Monotherapy
Novartis Pharmaceuticals n=718
NCT05301634 COMPLETED
Comparison Between Bilateral Infraorbital Block Versus Intranasal Bupivacaine in Transsphenoidal Pituitary Adenoma Resection
Cairo University n=60
NCT03944512 TERMINATED
Pravastatin to Prevent Preeclampsia
The George Washington University Biostatistics Center n=102
NCT03904693 COMPLETED
Clinical Study to Compare the Efficacy and Safety of Macitentan and Tadalafil Monotherapies With the Corresponding Fixed-dose Combination Therapy in Subjects With Pulmonary Arterial Hypertension (PAH)
Actelion n=187
NCT07251920 COMPLETED
Isometric Resistance Training and Dose-dependent Effects in Pre- and Hypertensive Adults
The University of Northampton n=30
NCT06165250 COMPLETED
A Study to Evaluate the Efficacy and Safety of Co-administrated BR1018B and BR1018C
Boryung Pharmaceutical Co., Ltd n=156
NCT06034743 COMPLETED
A Study to Investigate the Efficacy and Safety of Baxdrostat in Participants With Uncontrolled Hypertension on Two or More Medications Including Participants With Resistant Hypertension
AstraZeneca n=796
NCT02699645 COMPLETED
Triple Therapy Prevention of Recurrent Intracerebral Disease EveNts Trial
The George Institute n=1,671
NCT05385770 COMPLETED
Study to Evaluate and Compare the Efficacy and Safety of AZM and AML Combined and Alone in Mild-to-moderate Essential Hypertensive Subjects
Celltrion n=890
NCT05794555 COMPLETED
LiveSMART Trial to Prevent Falls in Patients With Cirrhosis
University of Michigan n=230
NCT03508739 SUSPENDED
Glucagon-like Peptide-1 Metabolism and Acute Neprilysin Inhibition
University of Pennsylvania n=25
NCT04630808 COMPLETED
MRCT Evaluating NCX 470 vs. Latanoprost in Subjects With Open-Angle Glaucoma or Ocular Hypertension
Nicox Ophthalmics, Inc. n=696
NCT03850782 COMPLETED
Evaluation of the Duration of Effect of Bimatoprost SR in Participants With Open-Angle Glaucoma or Ocular Hypertension
AbbVie n=515
NCT07116863 COMPLETED
A Multicenter, Randomized, Double-Blind Phase 3 Trial of KDF1901 in Patients With Essential Hypertension
Kyungdong Pharmaceutical Co., Ltd. n=286
NCT04780932 COMPLETED
Initial Dual Oral Combination Therapy Versus Standard-of-care Initial Oral Monotherapy Prior to Balloon Pulmonary Angioplasty in Patients With Inoperable Chronic Thromboembolic Pulmonary Hypertension
Assistance Publique - Hôpitaux de Paris n=96
NCT06685679 COMPLETED
Melatonin for Pulmonary Hypertension in Full Term Neonates
Ain Shams University n=40
NCT05920005 COMPLETED
Candesartan Cilexetil + Chlorthalidone + Amlodipine Versus Exforge HCT®️ for Systemic Arterial Hypertension
Hospital Israelita Albert Einstein n=702
NCT03187678 COMPLETED
Safety Study of the Switch From Oral Selexipag to Intravenous Selexipag in Subjects With Stable Pulmonary Arterial Hypertension
Actelion n=20
NCT04271475 TERMINATED
A Study to Evaluate Efficacy and Safety of Macitentan 75 mg in Inoperable or Persistent/Recurrent Chronic Thromboembolic Pulmonary Hypertension
Actelion n=127
NCT04445519 COMPLETED
Phase 3 Trial of NCX 470 vs. Latanoprost in Subjects With Open-Angle Glaucoma or Ocular Hypertension
Nicox Ophthalmics, Inc. n=691
NCT01191450 COMPLETED
Safety and Efficacy of Chlorthalidone + Amiloride to Elderly Patients Treatment With Arterial Hypertension
Eurofarma Laboratorios S.A. n=246
NCT03068130 TERMINATED
Extended Access Program to Assess Long-term Safety of Bardoxolone Methyl in Patients With Pulmonary Hypertension RANGER
Biogen n=261
NCT05170061 COMPLETED
24 Hour Ambulatory Cardiac Oxygen Consumption
State University of New York at Buffalo n=26
NCT05288400 COMPLETED
Evaluation of the Clinical Efficacy and Safety of Amlodipine 5mg/ Bisoprolol Fumarate 5mg /Perindopril Arginine 5mg Fixed-dose Combination in Capsule and Free Monotherapy at the Same Dose in Patients With Uncontrolled Essential Hypertension.
Servier n=150
NCT02657356 TERMINATED
Bardoxolone Methyl in Patients With Connective Tissue Disease-associated Pulmonary Arterial Hypertension - CATALYST
Biogen n=202
NCT04518306 COMPLETED
Efficacy and Safety of GMRx2 Compared to Placebo for the Treatment of Hypertension
George Medicines PTY Limited n=755
NCT04518293 COMPLETED
Efficacy and Safety of GMRx2 Compared to Dual Combinations for the Treatment of Hypertension
George Medicines PTY Limited n=1,385
NCT04732221 COMPLETED
A Study of the Efficacy and Safety of Frespaciguat (MK-5475) in Participants With Pulmonary Arterial Hypertension (INSIGNIA-PAH: Phase 2/3 Study of an Inhaled sGC Stimulator in PAH) (MK-5475-007)
Merck Sharp & Dohme LLC n=168
NCT06000748 TERMINATED
NEPH-ROSIS (NEPHrology in CirRhOSIS) Pilot Trial: A Trial to Treat Acute Kidney Injury Among Hospitalized Cirrhosis Patients
University of California, San Francisco n=6
NCT04565990 COMPLETED
A Study of Selexipag in Participants Who Participated in a Previous Selexipag Study
Actelion n=43
NCT03422328 COMPLETED
A Clinical Study to Investigate the Long-term Safety of the Drug Macitentan in Patients With Pulmonary Hypertension Who Were Previously Treated With Macitentan in Clinical Studies.
Actelion n=151
NCT03809884 COMPLETED
Dietary Counseling or Potassium Supplement to Increase Potassium Intake in Patients With High Blood Pressure
Ottawa Hospital Research Institute n=7
NCT04944290 COMPLETED
To Compare the Efficacy and Safety of Perrigo's Product to an FDA Approved Product for the Treatment of Glaucoma or Ocular Hypertension in Both Eyes
Padagis LLC n=447
NCT02558231 COMPLETED
The Efficacy and Safety of Initial Triple Versus Initial Dual Oral Combination Therapy in Patients With Newly Diagnosed Pulmonary Arterial Hypertension
Actelion n=247
NCT00667823 COMPLETED
Clinical Study to Assess the Long-term Safety and Tolerability of ACT 064992 in Patients With Symptomatic Pulmonary Arterial Hypertension
Actelion n=550
NCT02112487 COMPLETED
Extension of the Psychometric Validation Study ORCHESTRA in Patients With PAH
Actelion n=88
NCT05998837 COMPLETED
GLUcose Transport and REnalPROtection in Chronic Kidney Disease
IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy n=34
NCT04927299 COMPLETED
Efficacy and Safety of Losartan/Chlorthalidone vs Losartan/Hydrochlorothiazide in Essential Arterial Hypertension
Laboratorios Silanes S.A. de C.V. n=163
NCT02235909 COMPLETED
An Efficacy and Safety Study in Children 6 to Less Than 18 Years of Age With Hypertension
Arbor Pharmaceuticals, Inc. n=377
NCT03726398 WITHDRAWN
CompRehensive Phenotypic Characterization of Patients With Scleroderma-Associated ILD and PH
Franz Rischard, DO
NCT06438172 COMPLETED
A Study to Evaluate Efficacy and Safety of HCP1803 Compared to RLD2001-1 in Patients with Essential Hypertension
Hanmi Pharmaceutical Company Limited n=249
NCT05838846 COMPLETED
Inhaled Versus Intravenous Milrinone for Patients Undergoing Mitral Valve Replacement Surgery
Menoufia University n=60
NCT01223352 COMPLETED
Effects of Two Dosing Regimens of Bosentan in Children With Pulmonary Arterial Hypertension
Actelion n=64
NCT01470144 COMPLETED
Epoprostenol for Injection in Patients With Pulmonary Arterial Hypertension
Actelion n=41
NCT03001414 TERMINATED
Study of Angiogenic Cell Therapy for Progressive Pulmonary Hypertension
Northern Therapeutics n=22
NCT05878561 COMPLETED
A Study to Evaluate the Efficacy and Safety of BR1015 Combination Therapy
Boryung Pharmaceutical Co., Ltd n=248
NCT04752475 COMPLETED
Lasix for the Prevention of De Novo Postpartum Hypertension
Columbia University n=82
NCT04668157 COMPLETED
A Study of TAK-536 in Children From 2 to Less Than 6 Years Old With High Blood Pressure
Takeda n=10
NCT03868124 COMPLETED
Clinical Study Comparing Two Models of a Travoprost Intraocular Implant
Glaukos Corporation n=560
NCT03519386 COMPLETED
Randomized Study Comparing Two Models of a Travoprost Intraocular Implant to Timolol Maleate Ophthalmic Solution, 0.5%
Glaukos Corporation n=590
NCT02620163 COMPLETED
Efficacy & Safety Study of YH22162 vs Telmisartan/Amlodipine in Patients With Hypertension Inappropriately Controlled on Telmisartan/Amlodipine Treatment
Yuhan Corporation n=381
NCT05930028 COMPLETED
A Study to Evaluate the Efficacy and Safety of BR1017A and BR1017B Combination Therapy in Essential Hypertension Patients With Primary Hypercholesterolemia
Boryung Pharmaceutical Co., Ltd n=148
NCT05557942 TERMINATED
Inhaled Imatinib Pulmonary Arterial Hypertension Clinical Trial - Follow Up Long Term Extension (IMPAHCT-FUL)
Aerovate Therapeutics n=186
NCT04576988 COMPLETED
A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension (MK-7962-003/A011-11)(STELLAR)
Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ USA n=324
NCT05227833 COMPLETED
Vonoprazan Efficacy to Prevent Post Variceal Band Ligation Ulcer
Alexandria University n=284
NCT05036135 TERMINATED
A Study of AV-101 (Dry Powder Inhaled Imatinib) in Patients With Pulmonary Arterial Hypertension (PAH)
Aerovate Therapeutics n=202
NCT03399604 COMPLETED
Investigation of the Safety and Pharmacology of Dry Powder Inhalation of Treprostinil
Liquidia Technologies, Inc. n=121
NCT05820880 COMPLETED
Efficacy and Safety of Perindopril 5 mg / Indapamide 1.25 mg / Amlodipine 5 mg Fixed Combination in Hypertension
Institut de Recherches Internationales Servier n=532
NCT05397600 COMPLETED
Efficacy and Safety Assessment of T4032 (Unpreserved Bimatoprost 0.01%) Versus Lumigan® 0.01% in Ocular Hypertensive or Glaucomatous Patients
Laboratoires Thea n=684
NCT06500689 COMPLETED
To Assess Allisartan Isoproxil/Sustained-Release Indapamide in Patients With Essential Hypertension Uncontrolled With Allisartan Isoproxil
Shenzhen Salubris Pharmaceuticals Co., Ltd. n=366
NCT02801617 TERMINATED
Non-inferiority of PRO-067 Ophthalmic Solution vs GAAP Ofteno® in Glaucoma or Ocular Hypertension
Laboratorios Sophia S.A de C.V. n=116
NCT06465264 COMPLETED
To Assess Allisartan Isoproxil/Amlodipine in Patients With Essential Hypertension Uncontrolled With Amlodipine or Allisartan Isoproxil
Shenzhen Salubris Pharmaceuticals Co., Ltd. n=499
NCT03689244 TERMINATED
A Study to Find Out if Selexipag is Effective and Safe in Patients With Chronic Thromboembolic Pulmonary Hypertension When the Disease is Inoperable or Persistent/Recurrent After Surgery and/or Interventional Treatment
Actelion n=128
NCT00756938 COMPLETED
Study of Losartan in Pediatric Patients With Hypertension (MK-0954-337)
Organon and Co n=101
NCT06448962 COMPLETED
Phase 3 Study to Evaluate the Efficacy and Safety of Co-administrated AD-2021 and AD-2022
Addpharma Inc. n=109
NCT05931224 COMPLETED
Clinical Trial to Evaluate the Efficacy and Safety of D064 and D702 Combination Therapy
Chong Kun Dang Pharmaceutical n=346
NCT02757872 COMPLETED
Effects of Vitamin D and Fish Oil on the Kidney in Hypertensives
Albert Einstein College of Medicine n=2,232
NCT04133311 COMPLETED
A Phase III Multinational Multicenter Investigator-Masked Randomized Active-Controlled Trial Comparing the Efficacy and Safety of DE-130A With Xalatan® in Patients With Open-Angle Glaucoma or Ocular Hypertension
Santen SAS n=386
NCT01307046 COMPLETED
MK-0954A in Japanese Patients With Essential Hypertension Not Adequately Controlled With Losartan (MK-0954A-352)
Organon and Co n=336
NCT01307033 COMPLETED
A Long-term Study of the Safety of MK-0954A in Patients With Essential Hypertension (MK-0954A-351)
Organon and Co n=278
NCT00739674 COMPLETED
SAALT: Subtracting Salt and Adding Losartan Trial (0954A-335)
Organon and Co n=992
NCT06413082 COMPLETED
Pharmacogenetics of Torasemide and Spironolactone in Hypertension Treatment
Ospedale San Raffaele n=38
NCT06416735 COMPLETED
Natriuretic Effect of Amiloride in Relation to the Alpha Adducin Gene (ADD-AMI) RS4961 Variant
Ospedale San Raffaele n=40
NCT02507687 COMPLETED
Comparison of Bimatoprost Sustained Release (SR) to Selective Laser Trabeculoplasty (SLT) in Adults With Open-Angle Glaucoma or Ocular Hypertension
AbbVie n=240
NCT03961360 COMPLETED
Effectiveness of Higher Aspirin Dosing for Prevention of Preeclampsia in High Risk Obese Gravida
The University of Texas Health Science Center, Houston n=220
NCT05359068 COMPLETED
Study to Evaluate the Efficacy and Safety of SPH3127 In Patients With Mild-moderate Essential Hypertension
Shanghai Pharmaceuticals Holding Co., Ltd n=957
NCT05347147 TERMINATED
A Trial to Determine the Efficacy and Safety of Presendin in IIH
Invex Therapeutics Ltd. n=14
NCT04615624 COMPLETED
Furosemide vs. Placebo for Severe Antepartum Hypertension
Melanie Maykin, MD n=65
NCT06121518 COMPLETED
Clinical Trial to Evaluate the Efficacy and Safety of D064 and D702 Combination Therapy Versus D064 or D702 Monotherapy
Chong Kun Dang Pharmaceutical n=235
NCT05331014 COMPLETED
To Evaluate the Efficacy and Safety in Patients With Dyslipidemia and Hypertension
JW Pharmaceutical n=155
NCT05450601 COMPLETED
A Study to Evaluate the Efficacy and Safety of HCP2102 in Essential Hypertension Patients
Hanmi Pharmaceutical Company Limited n=249
NCT03235232 COMPLETED
BREMEN Eye Drops Versus Combigan for Open-angle Glaucoma or Intraocular Hypertension
EMS n=406
NCT05022004 COMPLETED
A Therapeutic Equivalence Study in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension
Sun Pharmaceutical Industries Limited n=599
NCT01934582 COMPLETED
A Pharmacokinetic Substudy of the TDE-PH-304 Protocol
United Therapeutics n=13
NCT03496623 TERMINATED
A Phase 3 Adaptive Study to Evaluate the Safety and Efficacy of Inhaled Treprostinil in Participants With Pulmonary Hypertension (PH) Due to Chronic Obstructive Pulmonary Disease (COPD)
United Therapeutics n=188
NCT00810693 COMPLETED
A Study to Evaluate Efficacy and Safety of Oral BAY63-2521 in Patients With Pulmonary Arterial Hypertension (PAH)
Bayer n=445
NCT00855465 COMPLETED
A Study to Evaluate Efficacy and Safety of Oral BAY63-2521 in Patients With CTEPH.
Bayer n=262
NCT03825380 COMPLETED
Efficacy and Safety Assessment of T4032 Versus Lumigan® in Ocular Hypertensive or Glaucomatous Patients
Laboratoires Thea n=485
NCT00863681 COMPLETED
BAY63-2521:Long-term Extension Study in Patients With Pulmonary Arterial Hypertension
Bayer n=396
NCT00910429 COMPLETED
BAY63-2521 - Long-term Extension Study in Patients With Chronic Thromboembolic Pulmonary Hypertension
Bayer n=237
NCT04084678 TERMINATED
A Study of Ralinepag to Evaluate Effects on Exercise Capacity by CPET in Subjects With WHO Group 1 PH
United Therapeutics n=10
NCT04591808 TERMINATED
Efficacy and Safety of Atorvastatin + Perindopril Fixed-Dose Combination S05167 in Adult Patients With Arterial Hypertension and Dyslipidemia
Institut de Recherches Internationales Servier n=146
NCT05362110 COMPLETED
A Study to Evaluate Efficacy and Safety of HCP1803 in Patients With Essential Hypertension
Hanmi Pharmaceutical Company Limited n=361
NCT04830449 COMPLETED
Clinical Efficacy and Safety Evaluation of HCP1904-2 in Essential Hypertension Patients
Hanmi Pharmaceutical Company Limited n=122
NCT05199129 COMPLETED
Clinical Efficacy and Safety Evaluation of HCP1904-3 in Essential Hypertension Patients
Hanmi Pharmaceutical Company Limited n=166
NCT04820907 COMPLETED
Clinical Efficacy and Safety Evaluation of HCP1904-1 in Essential Hypertension Patients
Hanmi Pharmaceutical Company Limited n=123
NCT04488874 COMPLETED
Sodium Lactate and Brain Relaxation (LSD)
Centre Hospitalier Universitaire de Besancon n=50
NCT04970108 WITHDRAWN
Efficacy and Safety of Egito Association in the Treatment of Type II Diabetes Mellitus and Hypertension
EMS
NCT05144360 WITHDRAWN
Efficacy and Safety of Atenas Association in the Treatment of Type II Diabetes Mellitus and Hypertension
EMS
NCT03691649 COMPLETED
A Phase III Study Assessing the Efficacy and Safety of DE-117 Ophthalmic Solution Compared With Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Glaucoma or Ocular Hypertension - Spectrum 3 Study
Santen Inc. n=426
NCT05475665 COMPLETED
Clinical Efficacy and Safety Evaluation of Irbesartan High and Amlodipine Combined Therapy in Essential Hypertension Patients
Handok Inc. n=157
NCT05476354 COMPLETED
Clinical Efficacy and Safety Evaluation of Irbesartan and Amlodipine Combined Therapy in Essential Hypertension Patients
Handok Inc. n=271
NCT03691662 COMPLETED
A Phase III Study Assessing the Efficacy and Safety of DE-117 Ophthalmic Solution Compared With Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Glaucoma or Ocular Hypertension - Spectrum 4 Study
Santen Inc. n=417
NCT03267108 TERMINATED
A Study to Assess Pulsed Inhaled Nitric Oxide in Subjects With Pulmonary Fibrosis at Risk for Pulmonary Hypertension
Bellerophon Pulse Technologies n=145
NCT04898387 COMPLETED
Efficacy and Safety Assessment of T4030 Eye Drops Versus Ganfort® UD in Ocular Hypertensive or Glaucomatous Patients.
Laboratoires Thea n=554
NCT03822559 COMPLETED
A Study of DE-111A on the Treatment of Open Angle Glaucoma or Ocular Hypertension
Santen Pharmaceutical Co., Ltd. n=219
NCT04285580 COMPLETED
A Phase 3b Study Evaluating the 24-Hour Intraocular Pressure Lowering Effect of Bimatoprost SR in Patients With Open-Angle Glaucoma or Ocular Hypertension
AbbVie n=37
NCT03997097 WITHDRAWN
Efficacy of Phosphodiesterase-type 5 Inhibitors in Patients With Univentricular Congenital Heart Disease
University Hospital, Montpellier
NCT02617459 COMPLETED
Levobetaxolol Hydrochloride Eye Drops for Treatment of Primary Open-angle Glaucoma or Ocular Hypertension
Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd. n=366
NCT01722604 COMPLETED
Therapeutic Equivalence Study of Generic Brinzolamide vs Azopt
Bausch & Lomb Incorporated n=258
NCT02368665 COMPLETED
A Study to Evaluate the Efficacy and Safety of Amlodipine Besylate and Candesartan Cilexetil in Essential Hypertension Patient Who Are Not Adequately Controlled With Amlodipine Besylate Monotherapy
HK inno.N Corporation n=180
NCT02368652 COMPLETED
A Study to Evaluate the Efficacy and Safety of Amlodipine Besylate and Candesartan Cilexetil in Essential Hypertension Patient Who Are Not Adequately Controlled With Candesartan Cilexetil Monotherapy
HK inno.N Corporation n=181
NCT03541174 COMPLETED
A Research Study to Show the Effect of Aprocitentan in the Treatment of Difficult to Control (Resistant) High Blood Pressure (Hypertension) and Find Out More About Its Safety
Idorsia Pharmaceuticals Ltd. n=730
NCT04024072 COMPLETED
To Compare the Safety and Efficacy of Perrigo's Product to an FDA Approved Product for the Treatment of Glaucoma or Ocular Hypertension in Both Eyes
Padagis LLC n=495
NCT04620135 COMPLETED
Efficacy and Safety Study of Netarsudil 0.02% Ophthalmic Solution Compared to Ripasudil Hydrochloride Hydrate 0.4% Ophthalmic Solution in Japanese Subjects With Primary Open Angle Glaucoma or Ocular Hypertension
Aerie Pharmaceuticals n=245
NCT02725372 TERMINATED
Clinical Study of Pulsed, Inhaled Nitric Oxide Versus Placebo in Symptomatic Subjects With PAH
Bellerophon Pulse Technologies n=207
NCT03602781 WITHDRAWN
Study of PAH Subjects With LTOT Use That Have Demonstrated Improved Exercise Tolerance With the Use of Inhaled Nitric
Bellerophon Pulse Technologies
NCT04857840 TERMINATED
Randomized Study of Extended Treatment With Firibastat in Treatment-Resistant Hypertension (REFRESH)
Quantum Genomics SA n=419
NCT01077895 WITHDRAWN
The Influence of Fluid Removal Using Continuous Venovenous Hemofiltration (CVVH) on Intra-abdominal Pressure and Kidney Function
University Hospital, Ghent
NCT02633293 TERMINATED
An Open Label Extension Study to Evaluate Inhaled Treprostinil in Adult PH With ILD Including CPFE
United Therapeutics n=243
NCT04162366 WITHDRAWN
A Research Study to Show Aprocitentan is Efficacious and Safe to Treat Patients With Uncontrolled Blood Pressure and Chronic Kidney Disease.
Idorsia Pharmaceuticals Ltd.
NCT02802254 COMPLETED
Increasing Risk Perception of Physical Activity Using Patient-targeted Feedback.
Universitätsklinikum Hamburg-Eppendorf n=121
NCT03504124 COMPLETED
Multicomponent Intervention to Improve Hypertension Control in Central America
Institute of Nutrition of Central America and Panama n=1,854
NCT01620788 SUSPENDED
Comparison of Losartan Associated With Indapamide Versus Hyzaar® in the Hypertension Treatment
EMS n=636
NCT02630316 COMPLETED
Safety and Efficacy of Inhaled Treprostinil in Adult PH With ILD Including CPFE
United Therapeutics n=326
NCT03814109 WITHDRAWN
Efficacy and Safety of Leningrado Association in the Treatment of Hypertension
EMS
NCT05437224 COMPLETED
Efficacy and Safety Study of Ambrisentan in Chinese Patients With Pulmonary Arterial Hypertension
RenJi Hospital n=80
NCT03501966 TERMINATED
Surgical Idiopathic Intracranial Hypertension Treatment Trial
Jaeb Center for Health Research n=7
NCT01416636 COMPLETED
Efficacy and Tolerability of Subcutaneously Administered Treprostinil Sodium in Patients With Severe (Non-operable) Chronic Thromboembolic Pulmonary Hypertension (CTREPH)
SciPharm SàRL n=105
NCT01560637 COMPLETED
An Open-Label, Long-Term Study of Oral Treprostinil in Subjects With Pulmonary Arterial Hypertension
United Therapeutics n=471
NCT00657241 COMPLETED
Cardioprotective Benefits of Carvedilol-CR or Valsartan Added to Lisinopril
State University of New York at Buffalo n=30
NCT01952340 TERMINATED
The Efficacy of Dietary Flaxseed for the Reduction of Blood Pressure in Newly Diagnosed Hypertensive Individuals
St. Boniface Hospital n=50
NCT04005079 WITHDRAWN
Pilocarpine After Combined Cataract/Trabectome Surgery
Montefiore Medical Center
NCT02636946 COMPLETED
A Comparison of Bimatoprost SR to Selective Laser Trabeculoplasty in Patients With Open-Angle Glaucoma or Ocular Hypertension
Allergan n=144
NCT02913664 COMPLETED
Risk Reduction for Alzheimer's Disease
University of Texas Southwestern Medical Center n=513
NCT03450629 COMPLETED
Evaluation of Safety and Efficacy of PDP-716
Sun Pharma Advanced Research Company Limited n=682
NCT03284853 COMPLETED
Safety and Efficacy Study of PG324 (Netarsudil/Latanoprost 0.02% / 0.005%) Ophthalmic Solution Compared to GANFORT® Ophthalmic Solution in Open Angle Glaucoma or Ocular Hypertension
Aerie Pharmaceuticals n=436
NCT03009487 COMPLETED
A Clinical Trial to Evaluate the Efficacy and Safety of Olmesartan/Amlodipine/Rosuvastatin Combination Treatment in Patients With Concomitant Hypertension and Hyperlipidemia
Daewoong Pharmaceutical Co. LTD. n=265
NCT02918305 COMPLETED
Renal Denervation on Quality of 24-hr BP Control by Ultrasound In Resistant Hypertension
JIMRO Co., Ltd. n=140
NCT03927443 WITHDRAWN
A Comparative Study of SPARC's SDP-133 Once Daily and Lumigan in Subjects With Open Angle Glaucoma or Ocular Hypertension
Sun Pharmaceutical Industries Limited
NCT04121299 WITHDRAWN
Mechanism of Masked Hypertension - Intervention
University of Alabama at Birmingham
NCT01824290 COMPLETED
A Study of Tadalafil in Pediatric Participants With Pulmonary Arterial Hypertension (PAH)
Eli Lilly and Company n=35
NCT01422616 COMPLETED
Enhanced Control of Hypertension and Thrombolysis Stroke Study (ENCHANTED)
The George Institute n=4,587
NCT02914509 COMPLETED
Phase 3 Study Evaluating Safety and Efficacy of OTX-TP in Subjects With OAG or OHT
Ocular Therapeutix, Inc. n=565
NCT04753112 COMPLETED
Treatment of PH With Angiotensin II Receptor Blocker and Neprilysin Inhibitor in HFpEF Patients With CardioMEMS Device
Germans Trias i Pujol Hospital n=14
NCT03514641 COMPLETED
An Integrated Assessment of the Safety and Effectiveness of Bexagliflozin for the Management of Essential Hypertension
Theracos n=673
NCT01720524 COMPLETED
A Study To Evaluate Safety And Efficacy Of IV Sildenafil In The Treatment Of Neonates With Persistent Pulmonary Hypertension Of The Newborn
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. n=59
NCT03991442 COMPLETED
BR1010 in Patients With Essential Hypertension Patients Who do Not Adequately Respond to Fimasartan/Amlodipine Combination
Boryung Pharmaceutical Co., Ltd n=257
NCT02250651 COMPLETED
Efficacy and Safety of Bimatoprost Sustained-Release (SR) in Patients With Open-Angle Glaucoma or Ocular Hypertension
Allergan n=528
NCT04952051 COMPLETED
Enalapril Folic Acid Tablets Combined With CCB or Diuretic to Prevent Stroke in Patients With Type H Hypertension
Second Affiliated Hospital, School of Medicine, Zhejiang University n=1,000
NCT01392469 COMPLETED
Pharmacokinetic Effects of QTI571 on Sildenafil and Bosentan in Pulmonary Arterial Hypertension Participants
Novartis Pharmaceuticals n=21
NCT03809650 TERMINATED
A Clinical Study to Find Out if Macitentan is Effective and Safe in Japanese Patients With Chronic Thromboembolic Pulmonary Hypertension (CTEPH).
Actelion n=9
NCT00667719 COMPLETED
A Long Term Safety Study to Test the Combination of Aliskiren/ Amlodipine / Hydrochlorothiazide in Participants With Essential Hypertension
Novartis n=564
NCT04158076 COMPLETED
Evaluating the Efficacy and Safety of Co-administrated Rosuvastatin/Ezetimibe and Telmisartan/Amlodipine
Addpharma Inc. n=131
NCT03026426 COMPLETED
Effectiveness of a mHealth Intervention for the Treatment of Depression in People With Diabetes or Hypertension in Peru
Universidad Peruana Cayetano Heredia n=432
NCT01583881 TERMINATED
Denervation of the renAl sympathetIc nerveS in hearT Failure With nOrmal Lv Ejection Fraction
UMC Utrecht n=60
NCT00742014 TERMINATED
The Assessment of Right Ventricular Contractility in Response to Sildenafil
The Hospital for Sick Children n=10
NCT01007994 COMPLETED
Reduction of Night-time Blood Pressure in Pediatric Renal Transplant Recipients
Northwell Health n=33
NCT03785067 TERMINATED
Triple Therapy Prevention of Recurrent Intracerebral Disease EveNts Trial (TRIDENT) Cognitive Sub-Study
The George Institute n=1
NCT00945958 COMPLETED
Evaluation of Safety of SPARC0913 in Open Angle Glaucoma or Ocular Hypertension
Sun Pharma Advanced Research Company Limited n=161
NCT00947661 COMPLETED
Efficacy and Safety of SPARC0912 and Reference0912 in Open Angle Glaucoma or Ocular Hypertension
Sun Pharma Advanced Research Company Limited n=578
NCT03814148 WITHDRAWN
Efficacy and Safety of Leningrado 5 Association in the Treatment of Hypertension
EMS
NCT02662894 WITHDRAWN
Fixed-dose Combination of Valsartan + Rosuvastatin Versus Their Isolated Components for Hypertension and Dyslipidemia.
EMS
NCT04740840 COMPLETED
Anti Inflammatory Treatment of Hypertension
Affiliated Hospital of North Sichuan Medical College n=200
NCT03872232 COMPLETED
Evaluating the Efficacy and Safety of Co-administrated Rosuvastatin/Ezetimibe and Telmisartan
Addpharma Inc. n=180
NCT01224210 COMPLETED
Ambrisentan in Patients With Porto-pulmonary Hypertension A Multicenter Open Label Trial
Tufts Medical Center n=30
NCT02038179 COMPLETED
Center of Research Translation (CORT) Project 2
University of Alabama at Birmingham n=99
NCT00985322 COMPLETED
Angiotensin-converting-enzyme (ACE) Inhibitors in Hemodialysis
Mario Negri Institute for Pharmacological Research n=269
NCT04074551 COMPLETED
A Phase 3 Study to Compare the Efficacy and Safety of Co-administered HGP0608, HGP0904 and HCP1306 Versus HCP1701 in Patients With Hypertension and Dyslipidemia
Hanmi Pharmaceutical Company Limited n=145
NCT03037580 TERMINATED
Oral Treprostinil in Subjects With Pulmonary Hypertension Associated With Heart Failure With Preserved Ejection Fraction
United Therapeutics n=84
NCT02865733 COMPLETED
Study of Remodulin® in Pediatric Pulmonary Hypertension With Single Ventricular Physiology After Fontan Surgery
Shanghai Jiao Tong University School of Medicine n=36
NCT03043651 TERMINATED
Open-label Extension of Oral Treprostinil in Subjects With PH Associated With HFpEF
United Therapeutics n=48
NCT04592380 WITHDRAWN
Clevidipine vs Placebo or Standard of Care for Dyspnea and Blood Pressure Control in AHF
The Medicines Company
NCT00777920 COMPLETED
Study of Ambrisentan in Participants With Pulmonary Hypertension
Gilead Sciences n=140
NCT03657095 TERMINATED
A Study With BPS-314d-MR-PAH-303 in Participants With Pulmonary Arterial Hypertension
Lung Biotechnology PBC n=112
NCT02651870 COMPLETED
Trial to Evaluate the Efficacy and Safety of a Combination Therapy of Candesartan and Amlodipine Versus Candesartan Monotherapy in Hypertensive Patients Inadequately Controlled by Candesartan Monotherapy
Chong Kun Dang Pharmaceutical n=135
NCT02558023 TERMINATED
The Treatment of Hypertension Associated With Severe Preeclampsia (PE). A Trial of Urapidil Versus Nicardipine
University Hospital, Strasbourg, France n=14
NCT02247804 COMPLETED
Efficacy and Safety Study of Bimatoprost Sustained-Release (SR) in Participants With Open-angle Glaucoma or Ocular Hypertension
Allergan n=594
NCT03371173 TERMINATED
ORal IrON Supplementation With Ferric Maltol in Patients With Pulmonary Hypertension (ORION-PH-1)
Hannover Medical School n=22
NCT01408446 COMPLETED
Effects and Safety of Menthol on Blood Pressure and Metabolic Parameters in Prehypertensive and Mild Hypertensive Patients
Zhiming Zhu n=36
NCT01560624 COMPLETED
Phase III Clinical Worsening Study of UT-15C in Subjects With PAH Receiving Background Oral Monotherapy
United Therapeutics n=690
NCT02791438 COMPLETED
A Phase 3 Long-term Study of TAK-536 in Pediatric Patients 6 to Less Than 16 Years With Hypertension
Takeda n=27
NCT02782052 WITHDRAWN
Bronchodilator's Effects on Exertional Dyspnoea in Pulmonary Arterial Hypertension
Assistance Publique - Hôpitaux de Paris
NCT03257813 COMPLETED
Non-inferiority of PRO-122 Ophthalmic Solution vs KRYTANTEK Ofteno® in Glaucoma or Ocular Hypertension (CONFORTK)
Laboratorios Sophia S.A de C.V. n=60
NCT03338426 COMPLETED
A Study to Evaluate the Efficacy and Safety of Combination Treatment of Fimasartan/Atorvastatin in Patients With Essential Hypertension and Dyslipidemia
Boryung Pharmaceutical Co., Ltd n=133
NCT03816540 COMPLETED
Diaphragmatic Breathing and Heart Rate Variability Training for Improving Hypertension in Fragile X Associated Tremor/Ataxia
University of California, Davis n=20
NCT02979197 COMPLETED
Evaluation of Celecoxib Effects on Amlodipine in Subjects With Existing Hypertension Requiring Antihypertensives
Kitov Pharma Ltd n=105
NCT02722265 COMPLETED
Long-term Study of CS-3150 as Monotherapy or in Combination With Other Antihypertensive Drug in Japanese Patients With Essential Hypertension
Daiichi Sankyo Co., Ltd. n=368
NCT03273387 COMPLETED
The Role of Trimetazidine on Right Ventricle Function in Pulmonary Arterial Hypertension
Indonesia University n=26
NCT03419975 COMPLETED
A Multi-center, Randomized, Blinded Evaluator, Active Control, Parallel, Phase III Study to Evaluate the Efficacy and Safety of TJO-002 in POAG or Ocular Hypertension Patients
Taejoon Pharmaceutical Co., Ltd. n=146
NCT01873352 COMPLETED
Renal Artery Denervation In Addition to Catheter Ablation To Eliminate Atrial Fibrillation
Meshalkin Research Institute of Pathology of Circulation n=302
NCT02755259 COMPLETED
Acute Hemodynamic Effect of Acetazolamide in Pulmonary Hypertension
University of Zurich n=33
NCT02575092 COMPLETED
The Relationship Between HHcy and Contrast-induced Nephropathy in Hypertensive Patients After Coronary Artery Diagnosis and Treatment
Fuling Central Hospital of Chongqing City n=4,000
NCT03398785 COMPLETED
Adrenal Artery Ablation Treats Primary Aldosteronism
Third Military Medical University n=66
NCT02435303 TERMINATED
Effect of Sildenafil for Sustained PAH After MV Surgery (SUPERIOR Trial)
Asan Medical Center n=2
NCT02042014 COMPLETED
Open-label, Multi-center Protocol to Provide QTI571 to PAH Patients Who Participated in the Extension Study (A2301E1) in Japan
Novartis Pharmaceuticals n=8
NCT03156842 COMPLETED
Combination of Fimasartan/Amlodipine/Rosuvastatin in Patients With Essential Hypertension and Dyslipidemia
Boryung Pharmaceutical Co., Ltd n=138
NCT02558400 COMPLETED
Double-masked Study of PG324 Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension
Aerie Pharmaceuticals n=718
NCT02674854 COMPLETED
Double-masked Study of PG324 Ophthalmic Solution in Patients With Open-angle Glaucoma or Ocular Hypertension
Aerie Pharmaceuticals n=750
NCT01885390 COMPLETED
Registry to Evaluate the ROX COUPLER in Patients With Resistant or Uncontrolled Hypertension
ROX Medical, Inc. n=83
NCT01642498 COMPLETED
A Multicenter Study to Evaluate the ROX Arteriovenous Coupler in Patients With Treatment-Resistant Hypertension
ROX Medical, Inc. n=100
NCT02248961 COMPLETED
Efficacy and Safety Evaluating Study to Compare Kanarb (Fimasartan) and Cozaar® (Losartan) in Adult Patients With Grade I-II Arterial Hypertension
R-Pharm n=179
NCT01099774 COMPLETED
Safety and Efficacy of Different Formulations of Bimatoprost Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension
Allergan n=597
NCT01739400 TERMINATED
Clinical Study to Assess the Long-term Safety, Tolerability, and Efficacy of Macitentan in Subjects With Eisenmenger Syndrome
Actelion n=217
NCT01072643 TERMINATED
Sedation With Dexmedetomidine During Cardiac Catheterization
Aruna Nathan n=4
NCT03909945 COMPLETED
Evaluation of an Antihypertensive Food Supplement Based on Aqueous Extract From Annona Muricata Sheets
Yaounde Central Hospital n=21
NCT01302691 COMPLETED
MK-0954E Study in Participants With Hypertension (MK-0954E-357)
Merck Sharp & Dohme LLC n=327
NCT02480764 COMPLETED
Azilsartan Medoxomil (TAK-491) Compared to Valsartan in Chinese Participants With Hypertension
Takeda n=612
NCT01841762 COMPLETED
Clinical Study of Macitentan in Patients With Pulmonary Arterial Hypertension to Psychometrically Validate the PAH-SYMPACT Instrument
Actelion n=284
NCT02007629 COMPLETED
Riociguat Clinical Effects Studied in Patients With Insufficient Treatment Response to Phosphodiesterase-5 Inhibitor
Bayer n=61
NCT01560312 TERMINATED
Renal Denervation in Refractory Hypertension
Charles University, Czech Republic n=106
NCT03067688 COMPLETED
Clinical Trial of Temisartan/Amlodipine & Rosuvastatin in Subjects With Hypertension and Hyperlipidemia
Yuhan Corporation n=202
NCT00902538 COMPLETED
Hydrochlorothiazide as add-on to Olmesartan/Amlodipine in Hypertension
Daiichi Sankyo n=2,204
NCT00923091 COMPLETED
Parallel-Group Comparison of Olmesartan (OLM), Amlodipine (AML) and Hydrochlorothiazid (HCTZ) in Hypertension
Daiichi Sankyo n=2,689
NCT00649389 COMPLETED
Safety and Efficacy Study of a Triple Combination Therapy in Subjects With Hypertension
Daiichi Sankyo n=2,500
NCT00891267 COMPLETED
Effect of Two Doses of Olmesartan Medoxomil and Amlodipine on Vascular Markers in Hypertensive Patients With Metabolic Syndrome
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company n=60
NCT00676845 COMPLETED
Study to Determine if Olmesartan Medoxomil Has the Potential to Benefit the Cardiovascular System in Terms of Arterial Protection
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company n=133
NCT01838850 COMPLETED
Efficacy and Safety Study of Olmesartan Medoxomil, Amlodipine and Hydrochlorothiazide Combination Therapy in Patients With Hypertension Not Controlled With Olmesartan Medoxomil and Hydrochlorothiazide Combination Therapy
Daiichi Sankyo Korea Co., Ltd., a Daiichi Sankyo Company n=344
NCT02890173 COMPLETED
Study of CS-3150 in Patients With Essential Hypertension
Daiichi Sankyo Co., Ltd. n=1,001
NCT02808026 COMPLETED
Study of CS-3150 in Patients With Severe Hypertension
Daiichi Sankyo Co., Ltd. n=20
NCT02807974 COMPLETED
Study of CS-3150 in Hypertensive Patients With Type 2 Diabetes and Albuminuria
Daiichi Sankyo Co., Ltd. n=51
NCT01003639 COMPLETED
Idiopathic Intracranial Hypertension Treatment Trial
St. Luke's-Roosevelt Hospital Center n=165
NCT01749930 COMPLETED
Comparing the Safety and Efficacy of BOL-303259-X Ophthalmic Solution With Timolol Maleate Ophthalmic Solution in Subjects With Open-Angle Glaucoma or Ocular Hypertension
Bausch & Lomb Incorporated n=420
NCT01749904 COMPLETED
Comparing Safety and Efficacy of BOL-303259-X With Timolol Maleate in Subjects With Open-Angle Glaucoma or Ocular Hypertension
Bausch & Lomb Incorporated n=420
NCT00796510 TERMINATED
Study Providing Monotherapy (Sitaxsentan) And Combination Therapy (Sitaxsentan+Sildenafil) To Subjects With Pulmonary Arterial Hypertension (PAH) To Assess Long-Term Safety
Pfizer n=3
NCT02846662 COMPLETED
Effectiveness of a Mobile Technology Intervention for the Treatment of Depression
University of Sao Paulo General Hospital n=880
NCT02172040 COMPLETED
Study to Evaluate the Effect of Celecoxib on the Efficacy and Safety of Amlodipine in Subjects With Hypertension Requiring Antihypertensive Therapy
Kitov Pharmaceuticals, Ltd. n=152
NCT01254604 COMPLETED
Preservative-Free Tafluprost (MK-2452) for the Treatment of Open-Angle Glaucoma or Ocular Hypertension (MK-2452-002)
Merck Sharp & Dohme LLC n=190
NCT02609490 COMPLETED
Azilsartan in Chinese Patients With Mild and Moderate Hypertension
Lee's Pharmaceutical Limited n=304
NCT01847014 TERMINATED
Clinical Study of Macitentan in Patients With PAH to Psychometrically Validate PAH-SYMPACT Instrument
Actelion n=4
NCT01299376 COMPLETED
MK-0954E Phase III Long-Term Study in Participants With Hypertension (MK-0954E-356)
Merck Sharp & Dohme LLC n=286
NCT02059278 COMPLETED
Safety and Efficacy of T-2345 Compared to Xalatan in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension
Nephron Pharmaceuticals Corporation n=335
NCT00851929 COMPLETED
Ambrisentan (Letairis) for Sarcoidosis Associated Pulmonary Hypertension
Medical University of South Carolina n=16
NCT02182830 COMPLETED
24 Week Efficacy and Safety Study of Empagliflozin (BI 10773) in Hypertensive Black/African American Patients With Type 2 Diabetes Mellitus and Hypertension
Boehringer Ingelheim n=166
NCT01895972 COMPLETED
Long-Term Safety of Latanoprostene Bunod Ophthalmic Solution 0.024% in Japanese Subjects With OAG or OHT
Bausch & Lomb Incorporated n=130
NCT02066649 WITHDRAWN
Carvedilol vs Band Ligation vs Combination Therapy for Primary Prophylaxis of Variceal Bleeding
Rutgers, The State University of New Jersey
NCT02339584 COMPLETED
Efficacy and Safety of Brinzolamide/Brimonidine Fixed Combination BID Compared to Brinzolamide BID Plus Brimonidine BID in Subjects With Open-Angle Glaucoma (OAG) or Ocular Hypertension (OHT)
Alcon Research n=493
NCT02896621 COMPLETED
Effect of Antihypertensive Agents on Diastolic Function in Patients With Sleep Apnea
Hospital de Clinicas de Porto Alegre n=69
NCT02145104 COMPLETED
Efficacy/Safety of Cilnidipine Plus Valsartan Versus Valsartan in Patients With Hypertension
IlDong Pharmaceutical Co Ltd n=286
NCT02207491 COMPLETED
Double-masked Study of AR-13324 Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension
Aerie Pharmaceuticals n=411
NCT00922480 COMPLETED
Clinical Study to Evaluate the Antihypertensive Efficacy and Safety of Fimasartan in Hypertension Patients
Boryung Pharmaceutical Co., Ltd n=506
NCT02246764 COMPLETED
Study of Netarsudil (AR-13324) Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension
Aerie Pharmaceuticals n=93
NCT02207621 COMPLETED
Evaluation of Netarsudil (AR-13324) Ophthalmic Solution in Patients With Glaucoma and Ocular Hypertension
Aerie Pharmaceuticals n=756
NCT02558374 COMPLETED
Double-masked Study of Netarsudil (AR-13324) Ophthalmic Solution in Subjects With Glaucoma or Ocular Hypertension
Aerie Pharmaceuticals n=708
NCT00787306 COMPLETED
Cardiovascular Health And Risk Modification in Family Health Teams
University of Toronto n=229
NCT02081690 TERMINATED
A Pulmonary Arterial Hypertension Study With Macitentan to Validate the PAH-SYMPACT™ in France, Italy and Spain
Actelion n=160
NCT01743001 COMPLETED
Clinical Study to Evaluate the Effects of Macitentan on Exercise Capacity in Subjects With Eisenmenger Syndrome
Actelion n=226
NCT03210532 COMPLETED
Evaluate the Efficacy and Safety of Combination Treatment With DW1501-R1+DW1501-R2 Versus DW1501-R1 or DW1501-R2+DW1501-R3 in Patients With Hypertension and Dyslipidemia
Daewon Pharmaceutical Co., Ltd. n=129
NCT02471183 COMPLETED
Study to Assess the Tolerability and the Safety of the Transition From Inhaled Treprostinil to Oral Selexipag in Patients With Pulmonary Arterial Hypertension
Actelion n=34
NCT01318395 COMPLETED
Aliskiren on Retinal Vasculature Treatment Study
University of Erlangen-Nürnberg Medical School n=56
NCT01469169 COMPLETED
Inhaled Iloprost (Ventavis): Efficacy, Safety, and Pharmacokinetics (PK) Confirmation Study
Bayer n=27
NCT02623738 COMPLETED
A Study Assessing the Efficacy and Safety of DE-117 Ophthalmic Solution in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension -AYAME Study-
Santen Pharmaceutical Co., Ltd. n=253
NCT02999906 WITHDRAWN
Study to Compare Triple Therapy (Oral Treprostinil, Ambrisentan, and Tadalafil) With Dual Therapy (Ambrisentan, Tadalafil, and Placebo) in Subjects With Pulmonary Arterial Hypertension
United Therapeutics
NCT01788358 COMPLETED
Open-Label Long-Term Safety and Efficacy Study of Fixed Dose Combination of Nifedipine Gastrointestinal Therapeutic System and Candesartan Cilexetil in Subjects With Moderate to Severe Essential Hypertension
Bayer n=508
NCT01617681 COMPLETED
Efficacy, Safety and Tolerability of Multiple Doses of Valsartan in Children With Hypertension With or Without CKD
Novartis Pharmaceuticals n=127
NCT01178073 COMPLETED
A Study of First-Line Ambrisentan and Tadalafil Combination Therapy in Subjects With Pulmonary Arterial Hypertension (PAH)
GlaxoSmithKline n=610
NCT01960153 WITHDRAWN
Phosphodiesterase Type 5 Inhibition With Tadalafil Changes Outcomes in Heart Failure: Extent of Renal Damage
Massachusetts General Hospital
NCT01894022 TERMINATED
A Open Label Study to Assess the Long-term Safety, Tolerability and Efficacy of Ambrisentan in Subjects With Inoperable Chronic Thromboembolic Pulmonary Hypertension (CTEPH)
GlaxoSmithKline n=19
NCT00955903 COMPLETED
Calorie Restriction and Changes in Body Composition, Disease, Function, and Quality of Life in Older Adults
University of Alabama at Birmingham n=167
NCT02277691 COMPLETED
A Phase III Long-term Study of TAK-536TCH in Participants With Essential Hypertension
Takeda n=341
NCT01324999 COMPLETED
Tadalafil for Sarcoidosis Associated Pulmonary Hypertension
University of North Carolina, Chapel Hill n=12
NCT01026831 COMPLETED
Preservative-Free MK2452 (Tafluprost) for Open-Angle Glaucoma/Ocular Hypertension (MK2452-001)(COMPLETED)
Merck Sharp & Dohme LLC n=643
NCT01208558 COMPLETED
Grain Exercise Trial - Whole Grain Versus no Grain With or Without Physiotherapy-promoted Exercise for Waist Loss
Lund University n=105
NCT02644395 COMPLETED
Thiazide Diuretics for Hypertension in Kidney Transplant Recipients Using Tacrolimus
Erasmus Medical Center n=49
NCT00984308 COMPLETED
Diagnosis and Treatment of Sleep Apnea in Cerebrovascular Disease
VA Office of Research and Development n=225
NCT02969265 WITHDRAWN
An Efficacy and Safety Study Evaluating the Fixed-Dose Combination of Candesartan Plus Amlodipine in Participants With Mild/Moderate Essential Hypertension
Takeda
NCT02047019 WITHDRAWN
Monotherapy-Controlled Study of Nifedipine Gastrointestinal Therapeutic System and Candesartan Cilexetil in Combination in Subjects With Essential Hypertension Inadequately Controlled on Candesartan Cilexetil
Bayer
NCT01884012 COMPLETED
Effect of Long-term Oxygen Therapy on Exercise Capacity and Quality of Life in Patients With Pulmonary Arterial and Chronic Thromboembolic Pulmonary Hypertension
University of Zurich n=30
NCT02278614 COMPLETED
Efficacy and Safety Assessment of T2347 Versus Xalacom® in Ocular Hypertensive or Glaucomatous Patients
Laboratoires Thea n=242
NCT03055234 WITHDRAWN
Study to Evaluate Efficacy and Safety of Oral Treprostinil in Subjects With Pulmonary Hypertension (PH) Associated With Sickle Cell Disease (SCD)
United Therapeutics
NCT02572219 COMPLETED
Effects of a Nutraceutical Preparation on Cognitive Impairment in Hypertensive Patients
Neuromed IRCCS n=12
NCT01884675 TERMINATED
Ambrisentan for Inoperable Chronic Thromboembolic Pulmonary Hypertension.
GlaxoSmithKline n=33
NCT01237873 COMPLETED
Long Term Safety of SPA100 (Fixed-dose Combination of Aliskiren/Amlodipine) in Patients With Essential Hypertension
Novartis Pharmaceuticals n=150
NCT02166814 COMPLETED
A Randomized, Double-blind, Multicenter, Phase III Study to Evaluate the Efficacy and Safety of Combination of Fimasartan/Rosuvastatin in Comparison to Each Component Administered Alone in Patients With Essential Hypertension and Dyslipidemia
Boryung Pharmaceutical Co., Ltd n=140
NCT01741922 COMPLETED
Effectiveness of Night Administration of Low Dose Aspirin in Hypertensive Patients
Basque Health Service n=230
NCT01850901 COMPLETED
Renal Sympathetic Denervation as a New Treatment for Therapy Resistant Hypertension
UMC Utrecht n=139
NCT01977794 COMPLETED
Fixed Dose Combination of Bisoprolol and Amlodipine in the Treatment of Hypertension
Merck KGaA, Darmstadt, Germany n=200
NCT02521246 WITHDRAWN
Efficacy and Safety of Candesartan Associated With Chlorthalidone Versus Losartan Associated With Hydrochlorothiazide (Hyzaar®) in Essential Hypertension Control
EMS
NCT02521233 WITHDRAWN
Efficacy and Safety of Candesartan Associated With Chlorthalidone in Essential Arterial Hypertension Control
EMS
NCT00293735 WITHDRAWN
Labetalol Versus Magnesium Sulfate (MgSO4) for the Prevention of Eclampsia Trial
Baylor College of Medicine
NCT01785472 COMPLETED
Efficacy and Safety of LCZ696 in Comparison to Olmesartan in Asian Patients With Essential Hypertension
Novartis Pharmaceuticals n=1,438
NCT00624065 COMPLETED
Research Study To Test Carvedilol CR + Lisinopril Versus Lisinopril + Placebo In Patients With High Blood Pressure
GlaxoSmithKline n=348
NCT02770261 COMPLETED
Phase III Clinical Trial to Evaluate the Efficacy and Safety of DP-R208 and Each Monotherapy
Alvogen Korea n=219
NCT01217606 COMPLETED
Safety and Efficacy of Triple Combination Therapy in Patients With Primary Open-Angle Glaucoma or Ocular Hypertension
Allergan n=185
NCT02203916 COMPLETED
Azilsartan Medoxomil (TAK-491) Compared to Placebo in Korean Adults With Hypertension
Takeda n=328
NCT02565173 COMPLETED
Study of Trabodenoson in Adults With Ocular Hypertension or Primary Open-angle Glaucoma
Inotek Pharmaceuticals Corporation n=303
NCT02738632 COMPLETED
Efficacy and Safety of TAH Combination in Comparison With Telmisartan/Amlodipine Combination for Essential Hypertension Patients
IlDong Pharmaceutical Co Ltd n=300
NCT01598441 COMPLETED
Multicenter Study of Iloprost Inhaled in Pulmonary Hypertension After Repair of Congenital Heart Diseases (CHD)
Shanghai Jiao Tong University School of Medicine n=8
NCT02432937 COMPLETED
Corever in the Treatment of Hypertension
TSH Biopharm Corporation Limited n=134
NCT02587988 COMPLETED
Trial to Evaluate the Efficacy and Safety of HCP1302
Hanmi Pharmaceutical Company Limited n=232
NCT00778921 COMPLETED
Study to Evaluate the Efficacy and Safety of Combination Aliskiren/Amlodipine in Patients With Hypertension Not Adequately Responding to Amlodipine Alone
Novartis n=847
NCT01874470 TERMINATED
Renal Denervation by Allegro System in Patients With Resistant Hypertension
Shanghai AngioCare Medical n=3
NCT02916602 COMPLETED
A Study to Evaluate Efficacy and Safety of HCP1401 for Stage 2 Hypertension Patients Not Controlled by HCP0605
Hanmi Pharmaceutical Company Limited n=340
NCT02899455 COMPLETED
Clinical Efficacy and Safety Evaluation of Co-administered HGP0904, HGP0608 and HGP0816 in Patients With Hypertension and Dyslipidemia
Hanmi Pharmaceutical Company Limited n=146
NCT00940667 COMPLETED
Efficacy/Safety of Amlodipine Plus Losartan Versus Amlodipine in Patients With Essential Hypertension
Hanmi Pharmaceutical Company Limited n=185
NCT02586311 COMPLETED
CKD-330 Phase 3 Trial in Amlodipine Non-responder
Chong Kun Dang Pharmaceutical n=160
NCT01959828 COMPLETED
Confirmatory Study of IK-3001 in Japanese Subjects With Peri-/Post-op Pulmonary Hypertension Assoc. With Cardiac Surgery
Mallinckrodt n=18
NCT01896661 COMPLETED
Effect of Antihypertensive Agents Over Sleep Apnea
Hospital de Clinicas de Porto Alegre n=53
NCT02213159 COMPLETED
Dexmedetomidine for Postoperative Analgesia After Bariatric Surgery
American University of Beirut Medical Center n=60
NCT01365481 COMPLETED
Safety and Tolerability of Valsartan in Children 6 to 17 Years of Age
Novartis Pharmaceuticals n=150
NCT01672476 COMPLETED
A Multicenter, Phase 3 Study to Evaluate the Antihypertensive Efficacy and Safety of Fimasartan(BR-A-657∙K) 30mg Compared to Placebo in Patients With Mild to Moderate Essential Hypertension
Boryung Pharmaceutical Co., Ltd n=293
NCT01701726 COMPLETED
Effect of Acupuncture on Patients With Mild Hypertension
Chengdu University of Traditional Chinese Medicine n=400
NCT01613209 COMPLETED
Sevicontrol-1: Efficacy and Safety of a Fixed Combination of Olmesartan/ Amlodipine
Institut für Pharmakologie und Präventive Medizin n=83
NCT02304198 COMPLETED
Clinical Trial to Evaluate the Long-term Safety of Udenafil in Patient With PAH
Dong-A ST Co., Ltd. n=59
NCT02451150 COMPLETED
A Phase 3 Pharmacokinetic Study of TAK-536 (Azilsartan) in Pediatric Patients 6 to Less Than 16 Years With Hypertension
Takeda n=6
NCT01652001 COMPLETED
Drug-induced Xerostomia. Evaluation of Malic Acid 1%, Salivary Mucins and Buffering Capacity
Universidad de Granada n=185
NCT01911780 COMPLETED
Compare Efficacy and Safety of Telmisartan/Hydrochlorothiazide With Telmisartan/Hydrochlorothiazide Plus Amlodipine
Boehringer Ingelheim n=132
NCT01726049 COMPLETED
Sildenafil in HFpEF (Heart Failure With Preserved Ejection Fraction) and PH
University Medical Center Groningen n=52
NCT01151410 COMPLETED
An Extension Study to Evaluate the Long Term Safety, Tolerability and Efficacy of Aliskiren Compared to Enalapril in Pediatric Hypertensive Patients 6-17 Years of Age
Novartis Pharmaceuticals n=208
NCT01228032 COMPLETED
The Health Outcomes Management and Evaluation (HOME) Study
Emory University n=447
NCT01370005 COMPLETED
12 Week Efficacy and Safety Study of Empagliflozin (BI 10773) in Hypertensive Patients With Type 2 Diabetes Mellitus
Boehringer Ingelheim n=825
NCT00902174 COMPLETED
Imatinib (QTI571) in Pulmonary Arterial Hypertension
Novartis Pharmaceuticals n=202
NCT00829296 COMPLETED
Safety Study to Lower the Risk of Heart Failure is Also Effective in Reducing Stiffness of the Arteries
University of Chicago n=70
NCT01850160 COMPLETED
Efficacy/Safety Study of Valsartan and Chlorthalidone Conjugate Treatment Compared to Simple Treatment for Hypertension
Farma de Colombia SA n=124
NCT02105285 COMPLETED
Efficacy and Safety Study of OPC-1085EL Ophthalmic Solution in Subjects With Glaucoma or Ocular Hypertension
Otsuka Pharmaceutical Co., Ltd. n=193
NCT02105272 COMPLETED
Efficacy and Safety Study of OPC-1085EL Ophthalmic Solution in Subjects With Glaucoma or Ocular Hypertension
Otsuka Pharmaceutical Co., Ltd. n=237
NCT00741156 COMPLETED
The Acute Effects of the Angiotensin-converting Enzyme Inhibitor Enalaprilat on Flow Distribution
The Hospital for Sick Children n=12
NCT01876368 COMPLETED
Efficacy and Safety of LCZ696 Compared to Olmesartan in Essential Hypertensive Patients Not Responsive to Olmesartan
Novartis Pharmaceuticals n=376
NCT02616809 COMPLETED
Effects of Standing and Light-intensity Activity on Ambulatory Blood Pressure and Blood Glucose
Arizona State University n=10
NCT01310751 COMPLETED
Study of Inhaled Iloprost in Pediatric Pulmonary Hypertension (PH) After Surgery
Shanghai Jiao Tong University School of Medicine n=36
NCT01646671 COMPLETED
Safety and Tolerability and Efficacy of LCZ696 in Japanese Severe Hypertensive Patients
Novartis Pharmaceuticals n=35
NCT01663233 COMPLETED
Efficacy and Safety of LCZ696 200 mg + Amlodipine 5 mg in Comparison With Amlodipine 5 mg in Hypertensive Patients Not Responding to Amlodipine
Novartis Pharmaceuticals n=266
NCT01615198 COMPLETED
Efficacy and Safety of LCZ696 in Comparison to Olmesartan in Elderly Patients With Essential Hypertension
Novartis Pharmaceuticals n=588
NCT01599104 COMPLETED
Efficacy and Safety of LCZ696 in Comparison to Olmesartan in Japanese Patients With Essential Hypertension
Novartis Pharmaceuticals n=1,161
NCT01150357 COMPLETED
Safety and Efficacy of Aliskiren in Pediatric Hypertensive Patients 6-17 Years of Age
Novartis Pharmaceuticals n=267
NCT00709098 COMPLETED
Safety Study Extension of Iloprost Power 15 in Pulmonary Arterial Hypertension
Actelion n=49
NCT00660179 COMPLETED
Study of Macitentan (ACT-064992) on Morbidity and Mortality in Patients With Symptomatic Pulmonary Arterial Hypertension
Actelion n=742
NCT01556997 COMPLETED
Perindopril Amlodipine for the Treatment of Hypertension
Symplmed Pharmaceuticals LLC n=837
NCT01541943 COMPLETED
Efficacy and Safety of HL-040XC in Essential Hypertension and Hyperlipidemia
HanAll BioPharma Co., Ltd. n=356
NCT02536326 COMPLETED
LEPU Renal Denervation System for Resistant Hypertension
Lepu Medical Technology (Beijing) Co., Ltd. n=50
NCT01939392 WITHDRAWN
Rapid Renal Sympathetic Denervation for Resistant Hypertension II
Medtronic Endovascular
NCT01117987 TERMINATED
Extension to QTI571A2301 to Evaluate the Long-term Safety, Tolerability and Efficacy of Imatinib in Severe Pulmonary Arterial Hypertension (PAH)
Novartis Pharmaceuticals n=144
NCT01593787 COMPLETED
Safety and Tolerability and Efficacy of LCZ696 in Japanese Hypertensive Patients With Renal Dysfunction
Novartis Pharmaceuticals n=32
NCT01392495 TERMINATED
Extension to CQTI571A2102 to Evaluate Long-term Safety, Tolerability and Efficacy of Imatinib in Severe Pulmonary Arterial Hypertension (PAH)
Novartis Pharmaceuticals n=17
NCT01988298 COMPLETED
Nonsteroidal Antiinflammatory Drugs in Women With Postpartum Pre-eclampsia
Complejo Hospitalario Dr. Arnulfo Arias Madrid n=114
NCT02152306 COMPLETED
Fimasartan/Amlodipine Combination Phase III
Boryung Pharmaceutical Co., Ltd n=143
NCT01652664 COMPLETED
Study of Travoprost Ophthalmic Solution, 0.004% Compared to Timolol (0.5% or 0.25%) in Pediatric Glaucoma Patients
Alcon Research n=184
NCT01342094 COMPLETED
DE-111 Against Timolol Ophthalmic Solution 0.5%
Santen Pharmaceutical Co., Ltd. n=166
NCT01342081 COMPLETED
DE-111 Against Tafluprost Ophthalmic Solution 0.0015% Alone and Concomitant Use of Tafluprost Ophthalmic Solution 0.0015% Plus Timolol Ophthalmic Solution 0.5%
Santen Pharmaceutical Co., Ltd. n=489
NCT02466490 COMPLETED
Efficacy and Safety of Fimasartan Alone or Combined With HCTZ in Mexican Patients With Essential Hypertension
Stendhal Americas, S.A. n=272
NCT01830140 COMPLETED
A Safety Study of Bimatoprost in Patients With Glaucoma or Ocular Hypertension
Allergan n=466
NCT01496430 TERMINATED
Efficacy and Safety of Azilsartan Medoxomil Used in Combination With Metformin in Participants With Hypertension and Diabetes
Takeda n=105
NCT01910389 TERMINATED
Phosphodiesterase Type 5 Inhibition With Tadalafil Changes Outcomes in Heart Failure
Carelon Research n=23
NCT01482364 COMPLETED
BEtter Control of Blood Pressure in Hypertensive pAtients Monitored Using the HOTMAN® sYstem
Hemo Sapiens, Inc. n=183
NCT00796666 TERMINATED
Study Looking at Combination Therapy (Sitaxsentan+Sildenafil) Vs. Monotherapy (Sitaxsentan Alone) SR-PAAS -Sitaxsentan Efficacy And Safety Trial With A Randomized Prospective Assessment Of Adding Sildenafil
Pfizer n=131
NCT00795639 TERMINATED
Sitaxsentan Efficacy And Safety Trial With A Randomized Prospective Assessment Of Adding Sildenafil (SR-PAAS)
Pfizer n=183
NCT01095185 COMPLETED
Efficacy of Statin Association With Standard Treatment in Prevention of Recurrent Hemorrhage in Patient With Cirrhosis and Variceal Bleeding
Juan A. Arnaiz n=150
NCT02376075 COMPLETED
Effects of Linagliptin on Endothelial- , Renal-, and Retinal Function in Patients With Hypertension and Albuminuria
ikfe-CRO GmbH n=43
NCT00971165 COMPLETED
Diuretics and Angiotensin-Receptor Blocker Agents in Patients With Stage I Hypertension
Hospital de Clinicas de Porto Alegre n=655
NCT00970931 COMPLETED
Hypertension Prevention in Pre-Hypertensive Individuals
Hospital de Clinicas de Porto Alegre n=730
NCT01431716 COMPLETED
Epoprostenol for Injection (EFI/ACT-385781A) - Pulmonary Arterial Hypertension
Actelion n=42
NCT01499134 COMPLETED
Comparison of 2 Beta Blocker Drugs on Peripheral Arterial Disease in Patients With High Blood Pressure
Thomas Jefferson University n=17
NCT01918332 COMPLETED
Efficacy and Safety of Valsartan 160mg and Rosuvastatin 20mg in Patients With Hypertension and Hyperlipidemia
LG Life Sciences n=168
NCT01721707 WITHDRAWN
Latanoprost/Brinzolamide BID Versus Latanoprost BID in Patients With OAG or OH
Adapt Produtos Oftalmológicos Ltda.
NCT01131962 COMPLETED
Comparing Two Methods to Stop Vomiting of Blood Using the Endoscope
University of Alexandria n=200
NCT00746902 COMPLETED
Study of the Relationships Between Refractory Hypertension, Overweight/Obesity and Sleep Apnea Syndrome
University Hospital, Grenoble n=62
NCT00935766 TERMINATED
Effect of Fish Oil (Omega-3 Fatty Acids) on Arteries
Denver Health and Hospital Authority n=76
NCT01241240 COMPLETED
Safety and Efficacy of Triple Combination Therapy in Patients With Primary Open-Angle Glaucoma or Ocular Hypertension
Allergan n=192
NCT00666328 COMPLETED
Clevidipine in the Treatment of Patients With Acute Hypertension and Intracerebral Hemorrhage (ACCELERATE)
The Medicines Company n=37
NCT00803634 COMPLETED
Clevidipine in the Treatment of Blood Pressure in Patients With Acute Heart Failure (PRONTO)
The Medicines Company n=117
NCT01865188 WITHDRAWN
Study of the Efficacy and Safety of LCZ696 Alone and in Combination With Amlodipine in Patients With Hypertension
Novartis Pharmaceuticals
NCT01631227 COMPLETED
Comparison of the Effect of Eprosartan and Eprosartan Mesylate on Blood Pressure in Essential Hypertension
Abbott n=665
NCT00928590 COMPLETED
Safety Study of DuoTrav APS in Patients With Open-Angle Glaucoma or Ocular Hypertension
Alcon Research n=155
NCT00672997 COMPLETED
A Phase III Study of Travoprost/Timolol Combination in Patients With Open-Angle Glaucoma or Ocular Hypertension
Alcon Research n=301
NCT00892762 COMPLETED
Travoprost APS Versus Xalatan® in Patient Reported Outcomes and Ocular Surface Health
Alcon Research n=434
NCT00935077 COMPLETED
A Collaborative Model to Improve Blood Pressure (BP) Control and Minimize Racial Disparities
University of Iowa n=1,441
NCT01914432 COMPLETED
Efficacy and Safety Study of YH16410 Versus Rosuvastatin and Telmisartan Monotherapies in Patients With Hypertension and Hyperlipidemia
Yuhan Corporation n=210
NCT00989339 WITHDRAWN
Effects of Intralipid Versus Olive Oil Infusions on Endothelial Function, Immune Function, Inflammatory Markers
Emory University
NCT00820352 COMPLETED
Safety and Efficacy of Bosentan in Patients With Diastolic Heart Failure and Secondary Pulmonary Hypertension
University Teaching Hospital Hall in Tirol n=20
NCT01286558 COMPLETED
Comparison in Japan T80/A5 (Telmisartan 80 mg and Amlodipine 5 mg) and T40/A5 (Telmisartan 40 mg and Amlodipine 5 mg)
Boehringer Ingelheim n=225
NCT00618774 COMPLETED
An Open-label, Long-term Study of Telmisartan Plus Amlodipine Fixed-dose Combination
Boehringer Ingelheim n=259
NCT01204398 COMPLETED
Telmisartan+Amlodipine Fixed Dose Combination in Hypertension
Boehringer Ingelheim n=27
NCT01103960 COMPLETED
An Eight-week Randomized,Double-blind Study to Evaluate the Efficacy and Safety of Fixed-dose Combinations of T80+A5 Versus A5 Monotherapy in Patients With Hypertension Who Fail to Respond Adequately to Treatment With A5 Monotherapy
Boehringer Ingelheim n=324
NCT00624052 COMPLETED
26-week Open Study of telmisartan40mg+amlodipine10mg or telmisartan80mg+amlodipine10 mg in Hypertension
Boehringer Ingelheim n=838
NCT00860262 COMPLETED
Telmisartan and Amlodipine Fixed Dose Combination [FDC] Trial for the Treatment of Severe Hypertension
Boehringer Ingelheim n=858
NCT00879229 TERMINATED
ARTEMIS-PH - Study of Ambrisentan in Subjects With Pulmonary Hypertension Associated With Idiopathic Pulmonary Fibrosis
Gilead Sciences n=40
NCT01402843 COMPLETED
Efficacy, Safety of Coadministered Pitavastatin and Valsartan in Patients With Hypertension and Dyslipidemia
JW Pharmaceutical n=150
NCT02134626 COMPLETED
Simvastatin Effect on Portal Hypertension
Universidade Federal do Rio de Janeiro n=34
NCT01062763 COMPLETED
The Effect of Spironolactone on Blood Pressure in Type-2 Diabetics With Resistant Hypertension
Ib Abildgaard Jacobsen n=119
NCT01508026 COMPLETED
Study of the Efficacy and Safety of the Combination of Two FDA Approved Oral Medications, Nebivolol and Valsartan for Treatment of Stage 1 or 2 Hypertension
Forest Laboratories n=4,161
NCT01456169 COMPLETED
A Study to Evaluate the Effectiveness and Safety of a Fixed Dose Combination of Azilsartan Medoxomil and Chlorthalidone in Patients With High Blood Pressure Who do Not Achieve Target Blood Pressure Following Treatment With Azilsartan Medoxomil Alone
Takeda n=507
NCT01357616 COMPLETED
Fixed Combination Brinzolamide 1%/Timolol 0.5% Versus Brinzolamide 1% + Timolol 0.5% in Open-Angle Glaucoma or Ocular Hypertension
Alcon Research n=328
NCT01309204 COMPLETED
Brinzolamide/Brimonidine Twice a Day (BID) Fixed Combination (FC) vs Brinzolamide BID Plus Brimonidine BID in Patients With Open Angle Glaucoma or Ocular Hypertension
Alcon Research n=1,184
NCT00877929 COMPLETED
Telmisartan Fixed Dose Combination vs Amlodipine in Hypertensive Patients With Type 2 Diabetes Mellitus
Boehringer Ingelheim n=706
NCT01310777 COMPLETED
Brinzolamide/Brimonidine Twice a Day (BID) Fixed Combination (FC) vs Brinzolamide BID and Brimonidine BID in Patients With Open Angle Glaucoma or Ocular Hypertension
Alcon Research n=771
NCT02072330 COMPLETED
Study to Evaluate the Efficacy and Safety of Combined Administration of TAK-536CCB and Hydrochlorothiazide in Patients With Grade I or II Essential Hypertension.
Takeda n=353
NCT00872170 COMPLETED
Sildenafil to Improve Exercise Capacity in People With Thalassemia and Pulmonary Hypertension
Carelon Research n=27
NCT00614380 COMPLETED
Open Label Study Telmisartan and Amlodipine in Hypertension
Boehringer Ingelheim n=976
NCT01134393 COMPLETED
TElmisartan and AMlodipine Single Pill sTudy With Patients Not on Goal With Mono rAas Therapy-switch
Boehringer Ingelheim n=502
NCT01756430 COMPLETED
Efficacy and Safety of Carvedilol SR Versus Carvedilol IR in Patients With Essential Hypertension
Chong Kun Dang Pharmaceutical n=238
NCT01113047 COMPLETED
Aliskiren in Combination With Amlodipine in Hypertensive Patients Not Responding to Angiotensin Receptor Blocker (ARB) Plus Amlodipine
Novartis n=347
NCT01070056 COMPLETED
Practice-based Trial of Blood Pressure Control in African Americans
NYU Langone Health n=194
NCT01035554 COMPLETED
Behavioral Study to Control Blood Pressure
Milton S. Hershey Medical Center n=203
NCT01031680 COMPLETED
Efficacy and Safety in Patients With Type 2 Diabetes Mellitus, Cardiovascular Disease and Hypertension
AstraZeneca n=922
NCT01456286 COMPLETED
Randomized Controlled Trial to Assess the Effects of Sapropterin on Hepatic and Systemic Hemodynamics in Patients With Liver Cirrhosis and Portal Hypertension
Fundacion Clinic per a la Recerca Biomédica n=42
NCT01216943 COMPLETED
Safety and Efficacy of Triple Combination Therapy in Patients With Glaucoma or Ocular Hypertension
Allergan n=126
NCT01928628 COMPLETED
Phase III Clinical Study to Evaluate the Efficacy and Safety of the Combination of Lercanidipine/Valsartan in Hypertensive Patients
LG Life Sciences n=449
NCT00738972 TERMINATED
Left Ventricular Hypertrophy Reduction With Statins in Hypertensives Patients (MK0653A-168)
Fundación Lindavista del Corazón AC n=12
NCT01764295 COMPLETED
Clinical Study for Patients With Hypertension Associated With Dyslipidemia
Daewoong Pharmaceutical Co. LTD. n=150
NCT01442987 COMPLETED
Efficacy and Safety of Irbesartan and Atorvastatin in Hypertension and Hyperlipidemia
Hanmi Pharmaceutical Company Limited n=230
NCT01284166 WITHDRAWN
Safety and Efficacy of Triple Combination Therapy With Dorzolamide Hydrochloride / Brimonidine Tartrate / Timolol Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension
Allergan
NCT01297920 COMPLETED
Three Month Efficacy/Safety Study With a 3-Month Safety Extension of Brinzolamide 1%/Brimonidine 0.2% vs. Brinzolamide 1% or Brimonidine 0.2%
Alcon Research n=1,062
NCT01634295 COMPLETED
Efficacy and Safety of CKD-828 to Stage 2 Hypertension
Chong Kun Dang Pharmaceutical n=103
NCT01415505 COMPLETED
Combination of Nebivolol and Valsartan Given as Free Tablets for Stage 1 or Stage 2 Hypertension
Forest Laboratories n=812
NCT01087671 COMPLETED
Ocular Signs and Symptoms in Glaucoma Patients Switched From Latanoprost to Preservative Free Tafluprost Eye Drops
Santen Oy n=185
NCT01297517 COMPLETED
Efficacy and Safety Study of Brinzolamide 1%/Brimonidine 0.2% vs. Brinzolamide 1% and Brimonidine 0.2%
Alcon Research n=1,001
NCT01538875 COMPLETED
Hydralazine Versus Labetalol for the Management of Hypertensive Disorders of Pregnancy
Saint Thomas Hospital, Panama n=261
NCT01352065 COMPLETED
Characterization and Detection of Prolonged Endothelin Receptors Antagonists Administration
Center for Health Sciences, Serbia n=30
NCT00581607 COMPLETED
Double Blind, Randomized Trial of Bosentan for Sarcoidosis Associated Pulmonary Hypertension
University of Cincinnati n=43
NCT01177098 COMPLETED
Safety and Efficacy of a New Formulation of Bimatoprost/Timolol Ophthalmic Solution Compared With Bimatoprost/Timolol Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension
Allergan n=561
NCT00872651 COMPLETED
Travoprost 0.004%/Timolol 0.5% Versus Latanoprost 0.005%/Timolol in Chinese Patients With Open-Angle Glaucoma or Ocular Hypertension
Alcon Research n=242
NCT01292460 COMPLETED
Tafluprost-Timolol Preservative-free Fixed Dose Combination (FDC) Superiority Study Against Monotherapies
Santen Oy n=600
NCT00984750 COMPLETED
Acetyl-L-Carnitine in Type 2 Diabetes
Mario Negri Institute for Pharmacological Research n=229
NCT00760916 WITHDRAWN
FREEDOM DR: Oral Treprostinil in Combination With an Endothelin Receptor Antagonist (ERA) and/or a Phosphodiesterase-5 (PDE-5) Inhibitor or as Monotherapy for the Treatment of Pulmonary Arterial Hypertension (PAH)
United Therapeutics
NCT01625494 COMPLETED
Study of Efficacy and Safety of Irbesartan/Amlodipine 4 Fixed Combination Therapy in Hypertensive Patients Uncontrolled on Irbesartan or Amlodipine Monotherapy
Sanofi n=158
NCT00887978 COMPLETED
Efficacy and Safety of Oral UT-15C Tablets to Treat Pulmonary Arterial Hypertension
United Therapeutics n=310
NCT00927654 COMPLETED
Iloprost in High Risk Cardiac Surgical Patients
Ludwig-Maximilians - University of Munich n=253
NCT01440829 COMPLETED
The Effectiveness of L-ornithine-L-aspartate (LOLA) on Plasma Ammonia in Cirrhotic Patients After TIPS
Air Force Military Medical University, China n=40
NCT00691717 COMPLETED
Anecortave Acetate Safety in Patients With Open-Angle Glaucoma or Ocular Hypertension
Alcon Research n=201
NCT00713011 WITHDRAWN
Adalat XL vs Diltiazem on Proteinuria and Blood Pressure in Hypertensive Diabetic Patients
Bayer
NCT00760214 COMPLETED
Efficacy and Safety Study of Azilsartan Medoxomil Compared to Ramipril for Treating Essential Hypertension
Takeda n=885
NCT00996281 COMPLETED
Safety and Tolerability of Azilsartan Medoxomil Plus Chlorthalidone Compared to Olmesartan Medoxomil Plus Hydrochlorothiazide in Participants With Essential Hypertension
Takeda n=837
NCT00554619 COMPLETED
A Study to Evaluate GSK1325760A - a Long-Term Extension Study
GlaxoSmithKline n=21
NCT00767494 TERMINATED
Travoprost/Brinzolamide Fixed Combination Versus Travatan and Versus AZOPT
Alcon Research n=17
NCT01674491 COMPLETED
Effects of Black Soy Peptide Supplementation on Blood Pressure
Yonsei University n=100
NCT01135212 COMPLETED
The Clinical Study to Evaluate the Efficacy and Safety of Fimasartan in Patients With Mild to Moderate Essential Hypertension
Boryung Pharmaceutical Co., Ltd n=290
NCT00690794 COMPLETED
Travatan Z in Ocular Surface Health in Patients With Open-Angle Glaucoma or Ocular Hypertension
Alcon Research n=726
NCT00767481 TERMINATED
1 Year Study Trav/Brinz QD Fixed Combination Versus COSOPT
Alcon Research n=6
NCT01248234 WITHDRAWN
Does Administration of Etomidate and Propofol of the Anesthetic Induction of Elderly Hypertensive Patient Provide Superior Blood Pressure Stability in Response to Direct Laryngoscopy When Compared to Propofol or Etomidate Alone?
University of Mississippi Medical Center
NCT00865501 COMPLETED
Importance of Aldosterone in the Pathogenesis of Hypertensive Heart Disease
University of Erlangen-Nürnberg Medical School n=50
NCT01568983 COMPLETED
The Effects of Polyphenol-rich Berry Juice on Blood Pressure in Hypertensive Subjects
University of Oslo n=153
NCT01237223 COMPLETED
Efficacy and Safety of SPA100 (Fixed-dose Combination of Aliskiren/Amlodipine) in Patients With Essential Hypertension
Novartis n=1,342
NCT01306461 COMPLETED
Tafluprost-Timolol Fixed Dose Combination Non-Inferiority Study Against Concomitant Administrations
Santen Oy n=401
NCT01429662 COMPLETED
Modified Relaxation (MR) Technique for Treating Hypertension in Postmenopausal Women
Chiang Mai University n=429
NCT00826774 COMPLETED
Improving the Management of Obesity in Primary Care Practice (The Power-UP Trial)
University of Pennsylvania n=390
NCT01458236 WITHDRAWN
A Multinational, Multicenter, Study to Assess the Efficacy and Safety of BPS-314d-MR in Subjects With Pulmonary Arterial Hypertension Currently Receiving Treatment With an Endothelin Receptor Antagonist and/or a Phosphodiesterase-5 Inhibitor
Lung Biotechnology PBC
NCT00761319 COMPLETED
Phase III Clinical Trial of TRAVATAN Z in Ocular Surface Health
Alcon Research n=705
NCT01557647 WITHDRAWN
Safety and Efficacy of Inhaled Treprostinil in Patients With PAH
United Therapeutics
NCT00846365 COMPLETED
Efficacy and Safety of Azilsartan Medoxomil Plus Chlorthalidone in Participants With Moderate to Severe Hypertension
Takeda n=1,085
NCT01452009 WITHDRAWN
Three Month Safety and Efficacy Study of TRAVATAN® Versus Travoprost Ophthalmic Solution, 0.004%
Alcon Research
NCT00847626 COMPLETED
Efficacy and Safety of Azilsartan Medoxomil Combined With Chlorthalidone in Participants With Moderate to Severe Hypertension
Takeda n=1,711
NCT00818883 COMPLETED
Efficacy and Safety of Azilsartan Medoxomil and Chlorthalidone in Participants With Moderate to Severe Hypertension
Takeda n=609
NCT01033071 COMPLETED
Efficacy and Safety of Azilsartan Medoxomil and Chlorthalidone Compared to Olmesartan Medoxomil and Hydrochlorothiazide in Participants With Moderate to Severe Hypertension.
Takeda n=1,071
NCT01258673 COMPLETED
A Clinical Study to Evaluate Efficacy and Safety of Fimasartan/Hydrochlorothiazide Combination-therapy
Boryung Pharmaceutical Co., Ltd n=263
NCT01210443 TERMINATED
Long-Term Open-Label, Safety Study Of Sitaxentan Sodium In Japanese Pulmonary Arterial Hypertension Patients
Pfizer n=2
NCT01204853 TERMINATED
A 12 Week Safety And Efficacy Study Of Sitaxentan Sodium In Japanese Pulmonary Arterial Hypertension Patients
Pfizer n=2
NCT00812695 COMPLETED
Effects of Continuous Positive Airway Pressure (CPAP) in Patients With Resistant Hypertension and Obstructive Sleep Apnea (OSA)
University of Sao Paulo n=40
NCT00797862 COMPLETED
Aliskiren and the Calcium Channel Blocker Amlodipine Combination as an Initial Treatment Strategy for Hypertension
Novartis n=1,254
NCT00777946 COMPLETED
Study to Evaluate the Efficacy and Safety of Combination Aliskiren/Amlodipine in Patients Not Adequately Responding to Aliskiren Alone
Novartis n=818
NCT00841672 COMPLETED
Efficacy and Safety of the Combination of Aliskiren (300 mg) and Amlodipine (10 mg) Compared to Amlodipine (10 mg) Monotherapy in Patients With Moderate to Severe Hypertension
Novartis n=485
NCT01168414 COMPLETED
A Study of Ganfort Versus Duotrav in Patients With Primary Open Angle Glaucoma or Ocular Hypertension
Ministry of Health, Malaysia n=42
NCT00706134 COMPLETED
Efficacy and Safety of Aliskiren 75 mg, 150 mg, and 300 mg in Elderly Patients With Essential Hypertension When Given With a Light Meal in a 8 Week Placebo-controlled Study
Novartis n=756
NCT01364181 COMPLETED
The Impact of Udenafil on Exercise Capacity in Severe Chronic Obstructive Pulmonary Disease (COPD) Patients
Seoul National University Hospital n=23
NCT00801671 COMPLETED
Russian Study of the Effect of Continuous Positive Airway Pressure (CPAP) in Hypertension
Russian Cardiology Research and Production Center n=50
NCT00739973 COMPLETED
Study to Evaluate the Efficacy and Safety of Aliskiren Alone and in Combination With Amlodipine in Essential Hypertension
Novartis Pharmaceuticals n=2,694
NCT00699192 COMPLETED
Safety, Tolerability, and Efficacy of Once Daily Amlodipine/Valsartan 5/80 as Compared to Amlodipine/Valsartan 5/40 or to Amlodipine 5 mg Monotherapy in Patients 65 Years of Age and Older With Essential Hypertension
Novartis Pharmaceuticals n=965
NCT00705575 COMPLETED
Efficacy and Safety of the Combination Aliskiren (300 mg) and Hydrochlorothiazide (25mg) to Aliskiren (300mg) Monotherapy in Patients With Staged II Hypertension
Novartis n=688
NCT01001572 COMPLETED
Efficacy and Safety of Valsartan/Amlodipine in Patients With Mild to Moderate Essential Hypertension
Novartis n=932
NCT00765674 COMPLETED
Efficacy and Safety of Aliskiren/Amlodipine/Hydrochlorothiazide in Patients With Moderate-severe Hypertension
Novartis n=1,191
NCT00867490 COMPLETED
Safety and Efficacy of Aliskiren + Hydrochlorothiazide (± Amlodipine 5 mg) in Patients With Moderate Hypertension
Novartis n=186
NCT00696436 COMPLETED
An Efficacy and Safety Study of Azilsartan Medoxomil Compared to Valsartan and Olmesartan in Participants With Essential Hypertension.
Takeda n=1,291
NCT00670787 COMPLETED
Combination Pill of Losartan Potassium and Hydrochlorothiazide for Improvement of Medication Compliance Trial
Kyushu University n=207
NCT00956644 COMPLETED
Irbesartan/Amlodipine in Hypertensive Patients Uncontrolled on Amlodipine 5 mg Monotherapy
Sanofi n=406
NCT00957554 COMPLETED
Irbesartan/Amlodipine in Hypertensive Patients Uncontrolled on Irbesartan 150 mg Monotherapy
Sanofi n=435
NCT01127217 COMPLETED
Efficacy/Safety of Amlodipine Plus Losartan Versus Amlodipine in Patients With Stage 2 Hypertension
Hanmi Pharmaceutical Company Limited n=149
NCT00878917 COMPLETED
Equivalence Study of Dorzolamide 2% Eye Drops Solution
Alfred E. Tiefenbacher (GmbH & Co. KG) n=32
NCT00718952 COMPLETED
The Efficacy and Safety of Vardenafil in the Treatment of Pulmonary Arterial Hypertension
Tongji University n=60
NCT00702312 COMPLETED
A Bengali Dietary Salt Study to Control Blood Pressure
Barts & The London NHS Trust n=56
NCT00940680 COMPLETED
Efficacy/Safety of Amlodipine Plus Losartan Versus Losartan in Patients With Essential Hypertension
Hanmi Pharmaceutical Company Limited n=142
NCT00596791 COMPLETED
Ocular Signs and Symptoms in Glaucoma Patients Switched From Latanoprost 0.005% to Preservative Free Tafluprost Eye Drops
Santen Oy n=150
Data: ClinicalTrials.gov · Trials registered 2008 onwards · Industry sponsors only