TheraRadar
Landscape Endocrine

Hyperthyroidism Clinical Trial Landscape

Data updated: May 20, 2026

26 clinical trials tracked since 2008

Hyperthyroidism is being studied across 26 clinical trials registered since 2008, with 10 programs currently active. The competitive pipeline includes 3 active Phase 3 trials, 2 active Phase 2 trials, and 4 active Phase 1 trials. Top industry sponsors include argenx, Biohaven Therapeutics Ltd., Merida Biosciences.

10 active
/
26 total (since 2008)
4
Phase 1 Active
7 total
2
Phase 2 Active
6 total
3
Phase 3 Active
7 total
2
Phase 4 Active
8 total

Top Industry Sponsors

Sorted by active Active Done Failed
argenx 2 0 0
Biohaven Therapeutics Ltd. 1 0 0
Merida Biosciences 1 0 0
Changchun GeneScience Pharmaceutical Co., Ltd. 1 0 0

Featured Phase 3 Trials

NCT04856488 RECRUITING
Preoperative Lugol's Solution in Graves' Disease and Toxic Nodular Goiter
Jan Calissendorff n=182
NCT05118542 COMPLETED
Effect of Hyperthyroidism and Its Treatment in Graves' Disease to Early Marker of Atherosclerosis
Indonesia University n=36
NCT01295333 COMPLETED
Assessing the Impact of the Early and Systematic Hormonal Replacement After Radio-isotopic Ablation of Graves'hyperthyroïdism on Quality of Life, Efficiency and Tolerance
Assistance Publique Hopitaux De Marseille n=200
NCT07570316 NOT YET RECRUITING
A Study to Assess Efficacy and Safety of Efgartigimod PH20 SC PFS in Adult Participants With Graves' Disease
argenx n=230
NCT07596849 NOT YET RECRUITING
A Study to Assess Efficacy and Safety of Efgartigimod PH20 SC PFS in Adult Participants With Graves' Disease.
argenx n=230

+ 2 more Phase 3 trials — see full database below

Hyperthyroidism — Trials Started by Year (last 10 years)

2016
1
2017
1
2018
1
2019
4
2020
0
2021
3
2022
1
2023
2
2024
0
2025
4
2026
3

TheraRadar.com

Full Trial Database

Complete sponsor table, every trial across all phases, plus competitive analytics. Sortable, filterable, exportable for Pro users.

Top Sponsors (all-time)

argenx
2
Biohaven Therapeutics Ltd.
1
Merida Biosciences
1
Changchun GeneScience Pharmaceutical Co., Ltd.
1
Immunovant Sciences GmbH
1
Apitope International NV
1

Active Trials by Phase

Phase 1
4
Phase 2
2
Phase 3
3
Phase 4
2

Enrollment Size Distribution

1-50
14
51-200
8
201-500
3
501-1k
1
1k+
0

All Industry Sponsors

Sorted by active Active Done Failed
argenx 2 0 0
Biohaven Therapeutics Ltd. 1 0 0
Merida Biosciences 1 0 0
Changchun GeneScience Pharmaceutical Co., Ltd. 1 0 0
NCT07570316 NOT YET RECRUITING
A Study to Assess Efficacy and Safety of Efgartigimod PH20 SC PFS in Adult Participants With Graves' Disease
argenx n=230
NCT04856488 RECRUITING
Preoperative Lugol's Solution in Graves' Disease and Toxic Nodular Goiter
Jan Calissendorff n=182
NCT07596849 NOT YET RECRUITING
A Study to Assess Efficacy and Safety of Efgartigimod PH20 SC PFS in Adult Participants With Graves' Disease.
argenx n=230
NCT05142904 TERMINATED
Radiofrequency Ablation Versus I-131 for Solitary Autonomous Thyroid Nodules
Rijnstate Hospital n=40
NCT04080505 TERMINATED
Does Potassium Iodide (SSKI) Reduce Vascularity in Graves' Thyroidectomy?
Columbia University n=29
NCT05118542 COMPLETED
Effect of Hyperthyroidism and Its Treatment in Graves' Disease to Early Marker of Atherosclerosis
Indonesia University n=36
NCT01295333 COMPLETED
Assessing the Impact of the Early and Systematic Hormonal Replacement After Radio-isotopic Ablation of Graves'hyperthyroïdism on Quality of Life, Efficiency and Tolerance
Assistance Publique Hopitaux De Marseille n=200

Full Hyperthyroidism Pipeline

Every sponsor, every trial across Phase 1–4. Sortable, filterable, exportable.

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Data: ClinicalTrials.gov · Trials registered 2008 onwards · Industry sponsors only