Liver Failure Clinical Trial Landscape
Data updated: May 20, 2026
78 clinical trials tracked since 2008
Liver Failure is being studied across 78 clinical trials registered since 2008, with 29 programs currently active. The competitive pipeline includes 5 active Phase 3 trials, 16 active Phase 2 trials, and 16 active Phase 1 trials. Top industry sponsors include Yaqrit Ltd, eGenesis, INC, Quell Therapeutics Limited.
29 active
/
78 total (since 2008)
16
Phase 1 Active
35 total
16
Phase 2 Active
40 total
5
Phase 3 Active
14 total
1
Phase 4 Active
8 total
Top Industry Sponsors
Sorted by active Active Done Failed
Yaqrit Ltd 2 0 0
eGenesis, INC 1 0 0
Quell Therapeutics Limited 1 0 0
Gilead 1 0 0
Beijing Continent Pharmaceutical Co, Ltd. 1 0 0
+ 4 more sponsors — see full table below
Featured Phase 3 Trials
NCT03627013 RECRUITING
Custodiol-N Solution Compared With Custodiol Solution in Organ Transplantation (Kidney, Liver and Pancreas)
Dr. F. Köhler Chemie GmbH n=362
NCT02584283 COMPLETED
Dual Hypothermic Oxygenated Perfusion of DCD Liver Grafts in Preventing Biliary Complications After Transplantation
Robert J. Porte n=157
NCT02786836 COMPLETED
13C-Methacetin Breath Test for the Prediction of Outcome in in ALI or ALF
University of Texas Southwestern Medical Center n=76
NCT01785082 COMPLETED
Fast-track LiveR: Study for the Early Identification of Low-risk Patients After Partial Liver Resection by the LiMAx-test
Humedics GmbH n=149
NCT01160978 COMPLETED
Donor Simvastatin Treatment in Organ Transplantation
Helsinki University Central Hospital n=84
+ 9 more Phase 3 trials — see full database below
Liver Failure — Trials Started by Year (last 10 years)
2016 6
2017 0
2018 3
2019 4
2020 2
2021 3
2022 4
2023 9
2024 4
2025 11
2026 3
TheraRadar.com
Full Trial Database
Complete sponsor table, every trial across all phases, plus competitive analytics. Sortable, filterable, exportable for Pro users.
Top Sponsors (all-time)
Yaqrit Ltd 2
eGenesis, INC 1
Quell Therapeutics Limited 1
Gilead 1
Beijing Continent Pharmaceutical Co, Ltd. 1
Dr. F. Köhler Chemie GmbH 1
Hexaell Biotech Co., Ltd. 1
Genfit 3
Vital Therapies, Inc. 3
Cellaion SA 2
Active Trials by Phase
Phase 1 16
Phase 2 16
Phase 3 5
Phase 4 1
Enrollment Size Distribution
1-50 32
51-200 33
201-500 3
501-1k 0
1k+ 0
All Industry Sponsors
Sorted by active Active Done Failed
Yaqrit Ltd 2 0 0
eGenesis, INC 1 0 0
Quell Therapeutics Limited 1 0 0
Gilead 1 0 0
Beijing Continent Pharmaceutical Co, Ltd. 1 0 0
Dr. F. Köhler Chemie GmbH 1 0 0
Hexaell Biotech Co., Ltd. 1 0 0
Genfit 0 1 2
Vital Therapies, Inc. 0 0 3
NCT07347275 NOT YET RECRUITING
A Novel Extracorporeal Liver Support Therapy In ALCF and to Evaluate the Efficacy of DIALIVE 2.0, a Liver Dialysis Device.
Yaqrit Ltd n=72
NCT03627013 RECRUITING
Custodiol-N Solution Compared With Custodiol Solution in Organ Transplantation (Kidney, Liver and Pancreas)
Dr. F. Köhler Chemie GmbH n=362
NCT07075315 NOT YET RECRUITING
National Collaborative Centre for Hepatic Regenerative Medicine (NC-CHRM): Evaluating Mesenchymal Stem-Cell (MSC) Therapy in Non-viral Acute on Chronic Liver Failure (ACLF) Patients - Phase-III Trial
Institute of Liver and Biliary Sciences, India n=100
NCT06884904 NOT YET RECRUITING
Umbilical Cord-derived Mesenchymal Stem Cell Infusion for Treating ACLF
National Engineering Center of Cell Products n=96
NCT06815770 NOT YET RECRUITING
Efficacy and Safety of Continuous Infusion of Terlipressin vs Bolus Terlipressin in ACLF Patients With Acute Esophageal Variceal Bleed
Institute of Liver and Biliary Sciences, India n=60
NCT03702920 TERMINATED
Short-term Survival of Subjects With Acute-on-chronic Liver Failure After Plasma Exchange With Human Serum Albumin 5%
Grifols Therapeutics LLC n=275
NCT02837939 WITHDRAWN
Transfer Factor Efficacy in the Management of Cirrhosis-associated Immune Dysfunction
Martin Janičko
NCT02584283 COMPLETED
Dual Hypothermic Oxygenated Perfusion of DCD Liver Grafts in Preventing Biliary Complications After Transplantation
Robert J. Porte n=157
NCT02786836 COMPLETED
13C-Methacetin Breath Test for the Prediction of Outcome in in ALI or ALF
University of Texas Southwestern Medical Center n=76
NCT01785082 COMPLETED
Fast-track LiveR: Study for the Early Identification of Low-risk Patients After Partial Liver Resection by the LiMAx-test
Humedics GmbH n=149
NCT01160978 COMPLETED
Donor Simvastatin Treatment in Organ Transplantation
Helsinki University Central Hospital n=84
NCT01383460 COMPLETED
Efficacy of Granulocyte Colony-stimulating Factor and Erythropoetin for Patients With Acute-on-chronic Liver Failure
Institute of Liver and Biliary Sciences, India n=55
NCT01452295 WITHDRAWN
Registry Protocol for Tracking Trial Subjects After VTI-206 Study Completion
Vital Therapies, Inc.
Data: ClinicalTrials.gov · Trials registered 2008 onwards · Industry sponsors only