Landscape → Dermatology

Skin Infections Clinical Trial Landscape

Data updated: May 20, 2026

58 clinical trials tracked since 2008

Skin Infections is being studied across 58 clinical trials registered since 2008, with 5 programs currently active. The competitive pipeline includes 1 active Phase 3 trials, 0 active Phase 2 trials, and 0 active Phase 1 trials. Top industry sponsors include GSK, Melinta Therapeutics, Inc., Durata Therapeutics Inc., an affiliate of Allergan plc.

5 active

58 total (since 2008)

Phase 1 Active

6 total

Phase 2 Active

21 total

Phase 3 Active

16 total

Phase 4 Active

18 total

Top Industry Sponsors

Sorted by active Active Done Failed

GSK 0 5 0

Melinta Therapeutics, Inc. 0 3 0

Durata Therapeutics Inc., an affiliate of Allergan plc 0 3 0

Featured Phase 3 Trials

NCT05584007 RECRUITING

Cellulitis Optimal Antibiotic Treatment

University of Southampton n=334

NCT02814916 COMPLETED

Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections in Children, Known or Suspected to be Caused by Susceptible Gram-positive Organisms, Including MRSA

AbbVie n=199

NCT02090764 COMPLETED

Efficacy and Safety of Ozenoxacin 1% Cream Versus Placebo in the Treatment of Patients With Impetigo

Ferrer Internacional S.A. n=412

NCT01252719 COMPLETED

Oritavancin Versus IV Vancomycin for the Treatment of Participants With Acute Bacterial Skin and Skin Structure Infection (SOLO I)

Melinta Therapeutics, Inc. n=968

NCT01252732 COMPLETED

Oritavancin Versus IV Vancomycin for the Treatment of Patients With Acute Bacterial Skin and Skin Structure Infection

Melinta Therapeutics, Inc. n=1,019

+ 11 more Phase 3 trials — see full database below

Skin Infections — Trials Started by Year (last 10 years)

2016

2017

2018

2019

2020

2021

2022

2023

2024

2025

2026

TheraRadar.com

Full Trial Database

Complete sponsor table, every trial across all phases, plus competitive analytics. Sortable, filterable, exportable for Pro users.

Top Sponsors (all-time)

GSK

Melinta Therapeutics, Inc.

Durata Therapeutics Inc., an affiliate of Allergan plc

LEO Pharma

Ferrer Internacional S.A.

NovaBay Pharmaceuticals, Inc.

Lytix Biopharma AS

AbbVie

CrystalGenomics, Inc.

Reig Jofre Group

Active Trials by Phase

Phase 3

Phase 4

Enrollment Size Distribution

1-50

51-200

201-500

501-1k

1k+

All Industry Sponsors

Sorted by active Active Done Failed

GSK 0 5 0

Melinta Therapeutics, Inc. 0 3 0

Durata Therapeutics Inc., an affiliate of Allergan plc 0 3 0

NCT05584007 RECRUITING

Cellulitis Optimal Antibiotic Treatment

University of Southampton n=334

NCT02814916 COMPLETED

Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections in Children, Known or Suspected to be Caused by Susceptible Gram-positive Organisms, Including MRSA

AbbVie n=199

NCT02090764 COMPLETED

Efficacy and Safety of Ozenoxacin 1% Cream Versus Placebo in the Treatment of Patients With Impetigo

Ferrer Internacional S.A. n=412

NCT01252719 COMPLETED

Oritavancin Versus IV Vancomycin for the Treatment of Participants With Acute Bacterial Skin and Skin Structure Infection (SOLO I)

Melinta Therapeutics, Inc. n=968

NCT01252732 COMPLETED

Oritavancin Versus IV Vancomycin for the Treatment of Patients With Acute Bacterial Skin and Skin Structure Infection

Melinta Therapeutics, Inc. n=1,019

NCT04287777 COMPLETED

Safety and Efficacy of Mupirocin Gel in Children With Impetigo

Reig Jofre Group n=467

NCT03556917 COMPLETED

The Effects of Iontophoresis in Women With Gynoid Hidrolipodystrophy.

Universidade Norte do Paraná n=30

NCT02127970 COMPLETED

Single Dose vs. Two Dose Regimen of Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections

Durata Therapeutics Inc., an affiliate of Allergan plc n=698

NCT00852540 COMPLETED

Retapamulin Versus Linezolid in the Treatment of SITL and Impetigo Due to MRSA

Stiefel, a GSK Company n=410

NCT00684177 COMPLETED

Retapamulin Versus Placebo in Secondarily-Infected Traumatic Lesions (SITL)

GlaxoSmithKline n=508

NCT01397461 COMPLETED

Efficacy and Safety of Ozenoxacin 1% Cream Versus Placebo in the Treatment of Patients With Impetigo

Ferrer Internacional S.A. n=465

NCT02512614 COMPLETED

Evaluation of Novel Antimicrobial Hand Towels

Centers for Disease Control and Prevention n=449

NCT01670032 COMPLETED

Vehicle Controlled Efficacy and Safety Study of Two Dose Regimens of CD07223 1.5% Topical Gel in Impetigo

NovaBay Pharmaceuticals, Inc. n=328

NCT01431339 COMPLETED

Efficacy and Safety of Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections

Durata Therapeutics Inc., an affiliate of Allergan plc n=739

NCT01339091 COMPLETED

Efficacy and Safety of Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections

Durata Therapeutics Inc., an affiliate of Allergan plc n=573

NCT01085929 COMPLETED

Incision and Drainage Versus Needle Aspiration in Soft Tissue Abscesses

University of Massachusetts, Worcester n=101

NCT03637400 COMPLETED

Short and Long Term Outcomes of Doxycycline Versus Trimethoprim-Sulfamethoxazole for Skin and Soft Tissue Infections Treatment

Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center

NCT00758862 COMPLETED

The Pharmacokinetics of 2% TD1414 Cream in Adults With Secondarily Infected Traumatic Lesions (SITL) or Impetigo

LEO Pharma

NCT00626795 COMPLETED

Efficacy, Safety, and Tolerability of TD1414 2% Cream in Impetigo and Secondarily Infected Traumatic Lesions (SITL)

LEO Pharma

NCT01593761 COMPLETED

Phase 2a Study of CG400549 for the Treatment of cABSSSI Caused by Methicillin-resistant Staphylococcus Aureus

CrystalGenomics, Inc.

NCT02052388 COMPLETED

Efficacy and Safety Study of Brilacidin to Treat Serious Skin Infections

Cellceutix Corporation

NCT01519778 COMPLETED

A Phase 2 Safety and Exploratory Skin Lesion Measurement of TR-701 FA Study

Trius Therapeutics LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

NCT01029782 COMPLETED

Comparison of Intravenous Cefazolin Plus Oral Probenecid With Oral Cephalexin for the Treatment of Cellulitis

Kelowna General Hospital

NCT03429595 COMPLETED

Study Evaluating the Safety, Tolerability, PK, and Activity of Topical ATx201 Gel in Outpatients With Impetigo

UNION therapeutics

NCT01209078 COMPLETED

GSK1322322 Versus Linezolid in the Treatment of Acute Bacterial Skin and Skin Structure Infection

GlaxoSmithKline

NCT00984022 COMPLETED

Aquacel Versus Iodoform Gauze for Filling Abscess Cavity Following Incision and Drainage

Valleywise Health

NCT00893048 WITHDRAWN

The Use of Oral Steroids in the Treatment of Cellulitis

Milton S. Hershey Medical Center

NCT00719810 COMPLETED

Safety and Efficacy Study of a Fluoroquinolone to Treat Complicated Skin Infections

Melinta Therapeutics, Inc.

NCT01803035 COMPLETED

A Phase II Study to Evaluate the Efficacy and Safety of Two Doses of LTX-109 in Impetigo

Lytix Biopharma AS

NCT01171326 COMPLETED

Study to Evaluate the Safety and Efficacy of Topical Minocycline FXFM244 in Impetigo Patients

Vyne Therapeutics Inc.

NCT01519492 COMPLETED

A Study of Safety, Tolerability, and Efficacy of AFN-12520000 in the Treatment of Acute Bacterial Skin and Skin Structure Infections Due to Staphylococci

Affinium Pharmaceuticals, Ltd

NCT01367314 COMPLETED

Safety and Efficacy of Topical NVC-422 Gel in Impetigo

NovaBay Pharmaceuticals, Inc.

NCT01223222 COMPLETED

A Study to Evaluate Safety, Tolerability and Efficacy of Lytixar™ (LTX-109) on Uncomplicated, Gram-positive, Skin Infection

Lytix Biopharma AS

NCT00671580 COMPLETED

Safety, Potential Efficacy, and Pharmacokinetics of PZ-601 in the Treatment of Complicated Skin and Skin Structure Infection

Protez Pharmaceuticals, Inc.

NCT07532941 NOT YET RECRUITING

Clinical Efficacy of Stopping Oral Antibiotics When Symptoms Stop, Compared to 'Finishing the Course'

Murdoch Childrens Research Institute

NCT05852262 ENROLLING BY INVITATION

High-dose Cephalexin for Cellulitis (HI-DOCC)

Ottawa Hospital Research Institute

NCT06982105 RECRUITING

Trimethoprim-sulfamethoxazole vs. Clindamycin for the Treatment of Children With Invasive MRSA Infections

Indiana University

NCT05899140 RECRUITING

Adjunctive Clindamycin for the Treatment of Skin and Soft Tissue Infections, a Randomized Controlled Trial

Frieder Schaumburg

NCT03929224 COMPLETED

The Use of Medical Grade Honey in the Prevention of Bone Anchored Hearing Aid Associated Skin Breakdown

Henry Ford Health System

NCT04471246 COMPLETED

High-dose vs. Standard-dose Cephalexin for Cellulitis

Ottawa Hospital Research Institute

NCT05070754 COMPLETED

Cold Atmospheric Plasma Device for Pediatric Molluscum and Verruca

Medical University of South Carolina

NCT06149117 COMPLETED

Bioequivalence Study of Azithromycin Capsule and Reference Formulation Sumamed * in Healthy Adult Subjects in China

Peking University People's Hospital

NCT03372941 TERMINATED

Hospital Avoidance Strategies for ABSSSI

Washington University School of Medicine

NCT01876628 COMPLETED

Adjunctive Clindamycin for Cellulitis: C4C Trial.

University Hospitals Bristol and Weston NHS Foundation Trust

NCT02775617 COMPLETED

Azithromycin - Ivermectin Mass Drug Administration for Skin Disease

London School of Hygiene and Tropical Medicine

NCT01419184 COMPLETED

Daptomycin Versus Vancomycin in Participants With Skin Infections Due to MRSA

Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

NCT02032654 TERMINATED

Duration of ANtibiotic Therapy for CEllulitis

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

NCT02582203 COMPLETED

Clinical and Economic Outcomes of Ceftaroline Fosamil for ABSSSI Documented or at Risk of MRSA

Wayne State University

NCT01126268 COMPLETED

Twice Daily Altabax Application for the Treatment of Uncomplicated Soft Tissue Infection

The University of Texas Health Science Center, Houston

NCT01626560 COMPLETED

The Effects of Daptomycin and Cytokines Production in Comparison With Vancomycin

Hospital Universitario Evangelico de Curitiba

NCT01549613 COMPLETED

Evaluation of Daptomycin for the Emergency Department Treatment of Complicated Skin and Skin Structure Infections

University of Cincinnati

NCT00746109 COMPLETED

Study of Wound Packing After Superficial Skin Abscess Drainage

NYU Langone Health

Full Skin Infections Pipeline

Every sponsor, every trial across Phase 1–4. Sortable, filterable, exportable.

Unlock with Pro

Data: ClinicalTrials.gov · Trials registered 2008 onwards · Industry sponsors only