NCT02354014 RECRUITING Pharmacokinetic Study to Evaluate Anti-mycobacterial Activity of TMC207 in Combination With Background Regimen (BR) of Multidrug Resistant Tuberculosis (MDR-TB) Medications for Treatment of Children/Adolescents With Pulmonary MDR-TB
Janssen Research & Development, LLC
NCT07525427 RECRUITING Bactericidal Activity of TBD09 in Combination With Other Drugs in Pulmonary Tuberculosis
Gates Medical Research Institute
NCT06997367 ACTIVE NOT RECRUITING Safety and Immunogenicity of a Mycobacterium Tuberculosis Vaccine MTBVAC in Healthy Indian Adults and Adolescents (BBV169/2024)
Bharat Biotech International Limited
NCT07517445 RECRUITING Bactericidal Activity and Safety of Nicotinamide in Combination With Bedaquiline, Pretomanid, and Linezolid in Drug-susceptible Pulmonary Tuberculosis
Gates Medical Research Institute
NCT06192160 RECRUITING Trial of Novel Regimens for the Treatment of Pulmonary Tuberculosis
National Institute of Allergy and Infectious Diseases (NIAID)
NCT03828201 ACTIVE NOT RECRUITING Efficacy and Tolerability of Bedaquiline, Delamanid, Levofloxacin, Linezolid, and Clofazimine to Treat MDR-TB
Boston University
NCT06205589 NOT YET RECRUITING Therapeutic ID93 + GLA-SE Vaccination in Participants With Rifampicin-Susceptible Pulmonary TB
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
NCT06272812 RECRUITING A Study to Evaluate the Efficacy, Safety and Immunogenicity of MTBVAC in Adolescents and Adults Living in a TB Endemic Region.
International AIDS Vaccine Initiative
NCT05547464 ACTIVE NOT RECRUITING Safety and Immune Responses After Vaccination With Two Investigational RNA-based Vaccines Against Tuberculosis in BCG Vaccinated Volunteers
BioNTech SE
NCT07467252 NOT YET RECRUITING AIPH-TB: AI-Optimised Pyrazinamide-Hydroxychloroquine vs Standard RIPE for Drug-Sensitive Pulmonary Tuberculosis - A Phase II RCT
Ministry of Health, Saudi Arabia
NCT05947890 RECRUITING Evaluating the Safety and Immunogenicity of MTBVAC
HIV Vaccine Trials Network
NCT07350174 NOT YET RECRUITING Phase 2a Trial of Alpibectir Plus Ethionamide for Tuberculosis Meningitis
BioVersys AG
NCT05556746 ACTIVE NOT RECRUITING Ultra-Short Course Bedaquiline, Clofazimine, Pyrazinamide and Delamanid Versus Standard Therapy for Drug-Susceptible TB
Brigham and Women's Hospital
NCT07393438 NOT YET RECRUITING Acetohydroxamic Acid Combined With a Short-Course Regimen for MDR-TB (AHA-PLUS)
Shanghai Pulmonary Hospital, Shanghai, China
NCT07124559 NOT YET RECRUITING A Study of Daily Rifapentine Combined With Isoniazid (1HP) for Tuberculosis Prevention in Children Less Than 13 Years of Age With and Without HIV
National Institute of Allergy and Infectious Diseases (NIAID)
NCT07170800 RECRUITING A Phase 2b Clinical Study of JDB0131 Benzenesulfonate Tablets
WestVac Biopharma Co., Ltd.
NCT07303699 RECRUITING ATORvastatin in Pulmonary TUBerculosis: a POPulation PharmacoKinetics -PharmacoDynamics Sub-study (ATORTUB popPK-PD)
Obafemi Awolowo University Teaching Hospital
NCT05122026 ACTIVE NOT RECRUITING Safety and Tolerability of 1 Month Daily (1HP) and 3 Months Weekly (3HP) Isoniazid and Rifapentine With Pharmacokinetics of Dolutegravir (DTG) in Pregnant People With HIV
The Aurum Institute NPC
NCT05122767 ACTIVE NOT RECRUITING Rifapentine and Isoniazid TB Preventive Therapy (3HP) for Children Taking Dolutegravir-based Antiretroviral Treatment (DOLPHIN KIDS)
The Aurum Institute NPC
NCT05807399 RECRUITING PanACEA - STEP2C -01
Michael Hoelscher
NCT06114628 RECRUITING Platform Assessing Regimens and Durations In a Global Multisite Consortium for TB
University College, London
NCT06199921 RECRUITING ATORvastatin in Pulmonary TUBerculosis
Obafemi Awolowo University Teaching Hospital
NCT06446245 RECRUITING Adjunctive Doxycycline for Central Nervous System Tuberculosis
National University Hospital, Singapore
NCT07129629 NOT YET RECRUITING Short-Course Regimen With Bedaquiline, Moxifloxacin and Pyrazinamide for Early Bactericidal Activity in Drug-Susceptible Tuberculosis
Shanghai Pulmonary Hospital, Shanghai, China
NCT07118059 NOT YET RECRUITING Effects of Adjunct Omega-3 Long Chain Polyunsaturated Fatty Acids in Pulmonary Tuberculosis Patient: an Early Bactericidal Activity and Inflammatory Trial
North-West University, South Africa
NCT06477185 RECRUITING Characterization of Tuberculosis Associated Lung Fibrosis and Respiratory Impairment, and Prevention Using Doxycycline
Makerere University
NCT06917495 NOT YET RECRUITING Short-Course Anti-tuberculosis Regimens for Mild Spinal Tuberculosis
Shandong University
NCT06748937 RECRUITING A Study of the Early Effects, Safety, and Acceptability of Oral Alpibectir in Combination With Ethionamide
TASK Applied Science
NCT06058299 ACTIVE NOT RECRUITING Phase 2 Trial Assessing TBAJ876 or Bedaquiline, with Pretomanid and Linezolid in Adults with Drug-sensitive Pulmonary Tuberculosis
Global Alliance for TB Drug Development
NCT06811025 ENROLLING BY INVITATION Phase II Clinical Study of Contezolid for the Treatment of Tuberculous Meningitis
Beijing Chest Hospital
NCT06811012 ENROLLING BY INVITATION Phase II Clinical Study of Contezolid for the Treatment of Bone and Joint Tuberculosis
Beijing Chest Hospital
NCT05534750 RECRUITING Evaluation of the Early Bactericidal Activity of Tedizolid and Linezolide Against Mycobacterium Tuberculosis (TEDITUB)
Assistance Publique - Hôpitaux de Paris
NCT07595042 NOT YET RECRUITING A Trial of Stratified Patient-Centered Treatment Regimens for Active TB (SPECTRA-TB)
National Institute of Allergy and Infectious Diseases (NIAID)
NCT03730181 COMPLETED Tuberculosis Clinical Trials Consortium Study 35
Centers for Disease Control and Prevention
NCT05007821 COMPLETED Linezolid Dosing Strategies in Drug-Resistant TB
National Institute of Allergy and Infectious Diseases (NIAID)
NCT03988933 COMPLETED 2R2: Higher Dose Rifampin for 2 Months vs Standard Dose Rifampin for Latent TB.
McGill University Health Centre/Research Institute of the McGill University Health Centre
NCT04930744 COMPLETED Safety and Tolerability of Metformin in People With Tuberculosis (TB) and Human Immunodeficiency Virus (HIV)
University of Massachusetts, Worcester
NCT03512249 COMPLETED Study to Evaluate H56:IC31 in Preventing Rate of TB Recurrence
International AIDS Vaccine Initiative
NCT05455112 COMPLETED Safety and Efficacy of RUTI® With the Standard of Treatment for Tuberculosis
Archivel Farma S.L.
NCT04919239 COMPLETED Clinical Trial to Investigate Therapeutic Vaccine (RUTI) Against Tuberculosis (TB)
Archivel Farma S.L.
NCT05630872 COMPLETED Pharmacokinetics and Safety of Double-dose Dolutegravir When Used With Rifapentine for HIV-associated Tuberculosis
National Institute of Allergy and Infectious Diseases (NIAID)
NCT05382312 COMPLETED Early Bactericidal Activity, Safety & Tolerability of Oral GSK3036656 in a Dual Combination With Novel and Established Antitubercular Agents, or Standard of Care in Adults With Rifampicin Susceptible Pulmonary Tuberculosis
GlaxoSmithKline
NCT04734652 COMPLETED INSTI's For The Management of HIV-associated TB
Centre for the AIDS Programme of Research in South Africa
NCT04550832 COMPLETED PanACEA DElpazolid Dose-finding and COmbination DEvelopment (DECODE)
LigaChem Biosciences, Inc.
NCT02906007 COMPLETED Evaluating the Pharmacokinetics, Safety, and Tolerability of Bedaquiline in Infants, Children, and Adolescents With Multidrug-Resistant Tuberculosis, Living With or Without HIV
National Institute of Allergy and Infectious Diseases (NIAID)
NCT04311502 TERMINATED Clofazimine- and Rifapentine-Containing Treatment Shortening Regimens in Drug-Susceptible Tuberculosis: The CLO-FAST Study
National Institute of Allergy and Infectious Diseases (NIAID)
NCT05473195 COMPLETED A Phase 2 Trial to Evaluate the EBA, Safety and Tolerability of Eto Alone and in Combination With BVL-GSK098
TASK Applied Science
NCT05539989 WITHDRAWN Safety and Immunogenicity of VPM1002 Vaccination or BCG Revaccination Against TB in Pre-Adolescents Living With and Without HIV in South Africa
International Maternal Pediatric Adolescent AIDS Clinical Trials Group
NCT06041919 TERMINATED Evaluating the Early Bactericidal Activity, Safety and Tolerability of Nebulised RESP301 in Adults With Tuberculosis
Thirty Respiratory Limited
NCT04152161 TERMINATED Bacille Calmette Guerin (BCG) Revaccination of Healthy Adolescents for the Prevention of Mycobacterium Tuberculosis Sustained Infection
Gates Medical Research Institute
NCT03141060 COMPLETED Evaluating the Pharmacokinetics, Safety, and Tolerability of Delamanid in Combination With Optimized Multidrug Background Regimen (OBR) for Multidrug-Resistant Tuberculosis (MDR-TB) in HIV-Infected and HIV-Uninfected Children With MDR-TB
National Institute of Allergy and Infectious Diseases (NIAID)
NCT03536117 COMPLETED Dose-Defining Safety and Immunogenicity Study of MTBVAC in South African Neonates
Biofabri, S.L
NCT00664313 COMPLETED TBTC Study 30: Safety and Tolerability of Low Dose Linezolid in MDR TB
Centers for Disease Control and Prevention
NCT05221502 COMPLETED Safety and Efficacy Evaluation of 4-month Regimen of OPC-167832, Delamanid and Bedaquiline in Participants With Drug-Susceptible Pulmonary TB
Otsuka Pharmaceutical Development & Commercialization, Inc.
NCT06873282 COMPLETED Phase 2 Study of the ТВ/Flu-05Е Tuberculosis Vaccine
Research Institute of Influenza, Russia
NCT05971602 TERMINATED Efficacy and Safety Evaluation of Two to Four Months of Treatment With the Combination Regimens of DBOS and PBOS in Adults With Pulmonary Tuberculosis
Gates Medical Research Institute
NCT05388448 COMPLETED EBA, Safety and Tolerability of Sanfetrinem Cilexetil
TASK Applied Science
NCT02365623 COMPLETED An Exploratory Study of TMC207 in Japanese Participants With Pulmonary Multi-Drug Resistant Tuberculosis (MDR-TB)
Janssen Pharmaceutical K.K.
NCT04179500 COMPLETED A Trial to Evaluate the Male Reproductive Safety of Pretomanid in Adult Male Participants With Drug Resistant Pulmonary Tuberculosis
Global Alliance for TB Drug Development
NCT02619994 COMPLETED Treatment Shortening of MDR-TB Using Existing and New Drugs
Seoul National University Hospital
NCT03702738 COMPLETED Adjunctive NAC in Adult Patients With Pulmonary Tuberculosis
The Aurum Institute NPC
NCT04021121 COMPLETED Adjunctive Linezolid for the Treatment of Tuberculous Meningitis
University of California, San Francisco
NCT03851588 COMPLETED Standard Versus Double Dose Dolutegravir in Patients With HIV-associated Tuberculosis
University of Cape Town
NCT02821832 COMPLETED Using Biomarkers to Predict TB Treatment Duration
National Institute of Allergy and Infectious Diseases (NIAID)
NCT04176250 COMPLETED Early Bactericidal Activity of TBA-7371 in Pulmonary Tuberculosis
Gates Medical Research Institute
NCT03160638 COMPLETED Azithromycin as Host-directed Therapy for Pulmonary Tuberculosis
University Medical Center Groningen
NCT04694586 SUSPENDED Drug Exposure and Safety of a Shorter Tuberculosis Treatment Based on High-Dose Rifampicin and Pyrazinamide
University Hospital, Linkoeping
NCT05284812 SUSPENDED A Phase Ⅱ Clinical Trial of the Recombinant Mycobacterium Tuberculosis Vaccine Freeze-dried (AEC/BC02)
Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
NCT03678688 COMPLETED A Phase 1/2 Trial of Multiple Oral Doses of OPC-167832 for Uncomplicated Pulmonary Tuberculosis
Otsuka Pharmaceutical Development & Commercialization, Inc.
NCT03557281 COMPLETED An Early Bactericidal Activity, Safety and Tolerability of GSK3036656 in Subjects With Drug-sensitive Pulmonary Tuberculosis
GlaxoSmithKline
NCT03891901 COMPLETED A Clinical Trial of the Safety, Pharmacokinetics and Hematologic Effects of Imatinib on Myelopoiesis in Adults When Given With and Without Isoniazid and Rifabutin
National Institute of Allergy and Infectious Diseases (NIAID)
NCT03882177 COMPLETED StAT-TB (Statin Adjunctive Therapy for TB): A Phase 2b Dose-finding Study of Pravastatin in Adults With Tuberculosis
National Institute of Allergy and Infectious Diseases (NIAID)
NCT04608955 COMPLETED Evaluation of Early Bactericidal Activity and Safety in Pulmonary Tuberculosis With WX-081
Shanghai Jiatan Pharmatech Co., Ltd
NCT03537495 COMPLETED Pharmacokinetic Study of Linezolid for TB Meningitis
Universitas Padjadjaran
NCT03174184 COMPLETED Early Bactericidal Activity of Rifampin + Meropenem + Amoxicillin/Clavulanate in Adults With Pulmonary TB
Johns Hopkins University
NCT02256696 COMPLETED Assessing PA-824 for Tuberculosis (the APT Trial)
Johns Hopkins University
NCT03456102 COMPLETED Statin Adjunctive Therapy for TB
Johns Hopkins University
NCT02371681 COMPLETED NexGen EBA Radiologic and Immunologic Biomarkers of Sterilizing Drug Activity in Tuberculosis
National Institute of Allergy and Infectious Diseases (NIAID)
NCT05896930 COMPLETED Study to Evaluate EBA, Safety and Tolerability of Carbapenems in Adults With Pulmonary Tuberculosis
TASK Applied Science
NCT01918397 COMPLETED Efficacy and Safety of Levofloxacin for the Treatment of MDR-TB
Boston University
NCT03959566 COMPLETED PanACEA Sutezolid Dose-finding and Combination Evaluation
Michael Hoelscher
NCT02613169 COMPLETED Infant TB Infection Prevention Study
University of Washington
NCT03982277 COMPLETED Safety and Efficacy of High Dose Rifampicin in Tuberculosis (TB)-HIV Co-infected Patients on Efavirenz- or Dolutegravir-based Antiretroviral Therapy
Makerere University
NCT02933281 COMPLETED MTBVAC Study in Adults With and Without Latent Tuberculosis Infection in South Africa
International AIDS Vaccine Initiative
NCT01936831 COMPLETED High-Dose Isoniazid Among Adult Patients With Different Genetic Variants of INH-Resistant Tuberculosis (TB)
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
NCT03941496 WITHDRAWN Azacytidine During Anti-tuberculosis Therapy
Andrew Dinardo
NCT04044001 COMPLETED BTZ-043 - Multiple Ascending Dose (MAD) to Evaluate Safety, Tolerability and Early Bactericidal Activity (EBA)
Michael Hoelscher
NCT05136833 WITHDRAWN Evaluation of Efficacy and Safety of the Concomitant of RUTI® Immunotherapy With the Standard Treatment in TB Patients
Archivel Farma S.L.
NCT02711735 TERMINATED Safety of RUTI® Vaccination in MDR-TB Patients
Archivel Farma S.L.
NCT02583048 COMPLETED Evaluating the Safety, Tolerability, and Pharmacokinetics of Bedaquiline and Delamanid, Alone and in Combination, For Drug-Resistant Pulmonary Tuberculosis
National Institute of Allergy and Infectious Diseases (NIAID)
NCT04629378 COMPLETED Evaluating the EBA of Meropenem With Amoxicillin/Clavulanate and Pyrazinamide or Bedaquiline in Adults With PTB
TASK Applied Science
NCT03819114 COMPLETED Pharmacokinetic Study to Evaluate Double-Dose Levonorgestrel Emergency Contraception in Combination With Efavirenz-Based Antiretroviral Therapy or Rifampicin-Containing Anti-Tuberculosis Therapy
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
NCT00685360 COMPLETED A Trial to Evaluate OPC 67683 in Participants With Pulmonary Sputum Culture-positive, Multidrug-resistant Tuberculosis (TB)
Otsuka Pharmaceutical Development & Commercialization, Inc.
NCT01131351 TERMINATED Safety and Pharmacokinetics (PK) in Multidrug-Resistant (MDR) Refractive Tuberculosis
Otsuka Pharmaceutical Development & Commercialization, Inc.
NCT01751568 COMPLETED Safety, Tolerance and Pharmacokinetics of Raltegravir-Containing Antiretroviral Therapy in Infants, Children Infected With HIV and TB
National Institute of Allergy and Infectious Diseases (NIAID)
NCT02651259 COMPLETED Evaluating PK, Tolerability, and Safety of Rifapentine and Isoniazid in Pregnant and Postpartum Women
National Institute of Allergy and Infectious Diseases (NIAID)
NCT02573350 COMPLETED A Trial to Evaluate Safety, Tolerability, and Efficacy of Orally Administered OPC-67683
Otsuka Pharmaceutical Development & Commercialization, Inc.
NCT02958709 COMPLETED Optimizing Treatment to Improve TBM Outcomes in Children
Johns Hopkins University
NCT03927313 COMPLETED Linezolid, Aspirin and Enhanced Dose Rifampicin in HIV-TBM
University of Cape Town
NCT02712424 COMPLETED DAR-901 TB Booster Vaccine to Prevent TB in Adolescents
Dartmouth-Hitchcock Medical Center
NCT01859923 COMPLETED A 6-Month Safety, Efficacy, and Pharmacokinetic (PK) Trial of Delamanid in Pediatric Participants With Multidrug Resistant Tuberculosis (MDR-TB)
Otsuka Pharmaceutical Development & Commercialization, Inc.
NCT00600782 COMPLETED Immunogenicity and Safety of a Candidate Tuberculosis (TB) Vaccine Given to Healthy Adults in a TB-endemic Region
GlaxoSmithKline
NCT02684240 COMPLETED A 14 Day Early Bactericidal Activity Study of Nitazoxanide for the Treatment of Tuberculosis
Weill Medical College of Cornell University
NCT01138202 COMPLETED Pharmacokinetics (PK) and Safety of 2 Different Doses of Lopinavir/Ritonavir in in HIV/Tuberculosis (TB) Co-infected Patients Receiving Rifampicin Containing Anti-tuberculosis Therapy
The HIV Netherlands Australia Thailand Research Collaboration
NCT02381470 COMPLETED Trial of Faropenem and Cefadroxil (in Combination With Amoxicillin/Clavulanic Acid and Standard TB Drugs) in Patients With Pulmonary Tuberculosis: Measurement of Early Bactericidal Activity and Effects on Novel Biomarkers
National University Hospital, Singapore
NCT03334734 TERMINATED Phase 2a Study of PBTZ169
Nearmedic Plus LLC
NCT02415985 COMPLETED Pharmacokinetics and Safety of Rifabutin 150 mg Once Daily Versus Rifabutin 300 mg Thrice Weekly
The HIV Netherlands Australia Thailand Research Collaboration
NCT02836483 COMPLETED A Phase II Clinical Study of LCB01-0371 to Evaluate the EBA, Safety and PK
LigaChem Biosciences, Inc.
NCT01865487 COMPLETED A Phase I/IIa AERAS-456 in HIV-Negative Adults With & Without Latent Tuberculosis Infection (C-035-456)
Aeras
NCT02781909 COMPLETED Potential Efficacy and Safety of Using Adjunctive Ibuprofen for XDR-TB Tuberculosis
Fundació Institut Germans Trias i Pujol
NCT01755598 COMPLETED Study to Evaluate the Efficacy of GlaxoSmithKline (GSK) Biologicals' Candidate Tuberculosis (TB) Vaccine in Adults
GlaxoSmithKline
NCT00944021 COMPLETED Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis (CL-010)
Global Alliance for TB Drug Development
NCT03011580 COMPLETED Vitamin D to Resolve Inflammation After Tuberculosis (ResolveD-TB)
Queen Mary University of London
NCT03563599 COMPLETED A Phase 2 Study to Evaluate Early Bactericidal Activity, Safety, Tolerability, and Pharmacokinetics of Multiple Oral Doses of Telacebec (Q203)
Qurient Co., Ltd.
NCT02075203 COMPLETED Evaluation of Safety, Immunogenicity, and Prevention of TB With AERAS-404 and BCG Revaccination in Healthy Adolescents
Aeras
NCT02114684 COMPLETED Improving Retreatment Success (IMPRESS)
Centre for the AIDS Programme of Research in South Africa
NCT02193776 COMPLETED A Phase 2 to Evaluate the Efficacy, Safety and Tolerability of Combinations of Bedaquiline, Moxifloxacin, PA-824 and Pyrazinamide in Adult Subjects With Drug-Sensitive or Multi Drug-Resistant Pulmonary Tuberculosis.
Global Alliance for TB Drug Development
NCT02412436 COMPLETED PK Study of Rifampicin Interactions With DMPA and Efavirenz in TB
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
NCT01098474 COMPLETED Safety and Immunogenicity Study of a Candidate Tuberculosis Vaccine in Healthy Infants
GlaxoSmithKline
NCT01669096 COMPLETED Study in Healthy Adults to Evaluate Gene Activation After Vaccination With GlaxoSmithKline (GSK) Biologicals' Candidate Tuberculosis (TB) Vaccine GSK 692342
GlaxoSmithKline
NCT02465216 COMPLETED Phase 2a ID93 + GLA-SE Vaccine Trial in TB Patients After Treatment Completion
Access to Advanced Health Institute (AAHI)
NCT02279875 COMPLETED A Phase 2 Trial to Evaluate the Efficacy and Safety of Linezolid in Tuberculosis Patients. (LIN-CL001)
Global Alliance for TB Drug Development
NCT01392911 COMPLETED Safety, Tolerability, Extended Early Bactericidal Activity and PK of Higher Doses Rifampicin in Adults With Pulmonary TB
Radboud University Medical Center
NCT01516203 COMPLETED Phase 2a EBA Trial of AZD5847
National Institute of Allergy and Infectious Diseases (NIAID)
NCT01262976 COMPLETED Safety and Immunogenicity Study of a Candidate Tuberculosis Vaccine in Human Immunodeficiency Virus (HIV)-Positive Adults
GlaxoSmithKline
NCT02349841 COMPLETED Phase 2 Trial to Evaluate the Early Bactericidal Activity, Safety and Tolerability of Meropenem Plus Amoxycillin/CA and Faropenem Plus Amoxycillin/CA in Adult Patients With Newly Diagnosed Pulmonary Tuberculosis
TASK Applied Science
NCT00621322 COMPLETED Safety and Immunogenicity Study of GSK Biologicals Tuberculosis Vaccines (692342) to Healthy Adults
GlaxoSmithKline
NCT00707967 COMPLETED Safety and Immunogenicity of a Candidate Tuberculosis (TB) Vaccine in HIV-positive Adults.
GlaxoSmithKline
NCT01424501 TERMINATED Safety and Immunogenicity of a Candidate Tuberculosis (TB) Vaccine in Adults With TB Disease
GlaxoSmithKline
NCT00950612 COMPLETED Safety and Immunogenicity of a Candidate Tuberculosis (TB) Vaccine in Healthy HIV Negative Adolescents
GlaxoSmithKline
NCT01498419 COMPLETED Evaluation of 8 Weeks of Treatment With the Combination of Moxifloxacin, PA-824 and Pyrazinamide in Patients With Drug Sensitive and Multi Drug-Resistant Pulmonary Tuberculosis (TB) (NC-002)
Global Alliance for TB Drug Development
NCT02729571 COMPLETED Dose-escalation Safety and Immunogenicity Study to Compare MTBVAC to BCG in Newborns With a Safety Arm in Adults
Biofabri, S.L
NCT02391415 COMPLETED Study to Evaluate the Safety and Immunogenicity of VPM1002 in Comparison With BCG in HIV-exposed/-Unexposed Newborn Infants in South Africa
Serum Institute of India Pvt. Ltd.
NCT03265977 WITHDRAWN A Phase II Study of H56:IC31 in Healthy Adolescents
Aeras
NCT01861730 COMPLETED Phase 1/II, Safety and Immunogenicity Study of AERAS-404 in BCG-Primed Infants
Aeras
NCT01589497 COMPLETED Essentiality of INH in TB Therapy
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
NCT01601626 TERMINATED Rifampin-Based Tuberculosis Treatment Versus Rifabutin-Based Tuberculosis Treatment in Persons With HIV
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
NCT00814671 COMPLETED Study of Daily Rifapentine for Pulmonary Tuberculosis
Johns Hopkins University
NCT02774993 COMPLETED Doxycycline in Human Pulmonary Tuberculosis
National University Hospital, Singapore
NCT01408914 COMPLETED Trial of High-Dose Rifampin in Patients With TB
Harvard University Faculty of Medicine
NCT01785186 COMPLETED Evaluation of SQ109, High-dose Rifampicin, and Moxifloxacin in Adults With Smear-positive Pulmonary TB in a MAMS Design
Michael Hoelscher
NCT01730664 COMPLETED PK/PD of Ertapenem In Patients With TB
University Medical Center Groningen
NCT01198366 COMPLETED Study of AERAS-402 in Healthy Infants
Aeras
NCT01215110 COMPLETED Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis (TMC207-CL001)
Global Alliance for TB Drug Development
NCT00728507 TERMINATED Rifapentine Plus Moxifloxacin for Treatment of Pulmonary Tuberculosis
Johns Hopkins University
NCT02281643 COMPLETED Concomitant Infections of Mansonella Perstans in Tuberculosis and Buruli Ulcer Disease Patients From Ghana
Kwame Nkrumah University of Science and Technology
NCT02336542 COMPLETED Phase IIb Clinical Study of Recombinant Mycobacterium Tuberculosis Allergen ESAT6-CFP10
Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
NCT02389322 COMPLETED Phase IIb Clinical Study of Recombinant Mycobacterium Tuberculosis Allergen ESAT6-CFP10 on Healthy People Aged 18-65
Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
NCT01215851 COMPLETED Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis With(J-M-Pa-Z) (NC-001)
Global Alliance for TB Drug Development
NCT01691534 COMPLETED Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis With Clofazimine (C)-TMC207 (J)-PA-824 (Pa)-Pyrazinamide (Z)
Global Alliance for TB Drug Development
NCT02313610 COMPLETED Efficacy and Safety of Qinbudan as an Adjunct Therapy for Retreatment Pulmonary Tuberculosis
Shanghai University of Traditional Chinese Medicine
NCT01017536 COMPLETED Safety and Immunogenicity of AERAS-402 in HIV-infected, Bacillus Calmette-Guerin (BCG)-Vaccinated Adults
Aeras
NCT01151189 COMPLETED Efficacy Against TB Disease, Safety, and Immunogenicity of MVA85A/AERAS-485 in HIV-Infected Adults (C-030-485)
Aeras
NCT00953927 COMPLETED A Study of MVA85A in Healthy Infants
Aeras
NCT02414828 COMPLETED A Study to Evaluate the Safety of AERAS-402 in Adults Recently Treated for Pulmonary TB
Aeras
NCT00727844 COMPLETED Linezolid to Treat Extensively-Drug Resistant Tuberculosis
National Institute of Allergy and Infectious Diseases (NIAID)
NCT01698476 COMPLETED Immune Reconstitution in Tuberculosis Disease
Karolinska Institutet
NCT01225640 COMPLETED PNU-100480 In Newly Diagnosed, Drug Sensitive Patients With Pulmonary TB; Early Bactericidal Activity; Whole Blood Assay
Sequella, Inc.
NCT01650389 COMPLETED Safety and Immunogenicity of MVA85A Prime and Bacille Calmette-Guerin Boost Vaccination
Mark Hatherill
NCT02481726 COMPLETED 68Ga-AlfatideII for the Differential Diagnosis of of Lung Cancer and Lung Tuberculosis by PET/CT
Xijing Hospital
NCT00910871 COMPLETED To Evaluate the Safety, Tolerability, and Efficacy of TMC207 as Part of an Individualized Multi-drug Resistant Tuberculosis (MDR-TB) Treatment Regimen in Participants With Sputum Smear-positive Pulmonary MDR-TB.
Janssen Infectious Diseases BVBA
NCT01241188 COMPLETED A Trial of the C-Tb Skin Test, When Given Intradermally to Adult Patients Recently Diagnosed With Active Tuberculosis (TB)
Statens Serum Institut
NCT02329730 COMPLETED Phase IIa Clinical Study of Recombinant Mycobacterium Tuberculosis Allergen ESAT6-CFP10
Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
NCT02121314 COMPLETED HRZE Fasted/Fed in Newly Diagnosed TB
University Medical Center Groningen
NCT01580007 COMPLETED Clinical Trial of Phenylbutyrate and Vitamin D in Tuberculosis (TB)
International Centre for Diarrhoeal Disease Research, Bangladesh
NCT02178748 COMPLETED Trial to Investigate the Effect of Schistosoma Mansoni Infection on the Response to Vaccination With MVA85A in BCG-vaccinated African Adolescents
University of Oxford
NCT01832987 COMPLETED Pharmacokinetic Parameters of Co-trimoxazole
University Medical Center Groningen
NCT00918086 COMPLETED Impact of Vitamin D Supplementation on Host Immunity to Mycobacterium Tuberculosis and Response to Treatment
Emory University
NCT00694629 COMPLETED TBTC Study 29: Rifapentine During Intensive Phase Tuberculosis (TB) Treatment
Centers for Disease Control and Prevention
NCT01479972 COMPLETED Study to Evaluate Safety and Immunogenicity of VPM1002 in Comparison With BCG in Newborn Infants in South Africa
Serum Life Science Europe GmbH
NCT01380119 COMPLETED Tuberculosis (TB) Immunotherapy Phase 2 Study
Lisichansk Regional Tuberculosis Dispensary
NCT00760149 COMPLETED Pharmacokinetics and Pharmacodynamics of High Versus Standard Dose Rifampicin in Patients With Pulmonary Tuberculosis
Radboud University Medical Center
NCT01932268 COMPLETED A Pilot Study for Pharmacokinetic Parameter of Colchicine in Patient Taking Rifampin
Seoul National University Hospital
NCT00822315 COMPLETED Efficacy and Safety of 2 Raltegravir Doses in Naive HIV-1-infected Patients Receiving Rifampin for Active Tuberculosis
ANRS, Emerging Infectious Diseases
NCT00651066 COMPLETED Pharmacokinetics of Rifabutin Combined With Antiretroviral Therapy in Patients With TB/HIV Co-infection in Vietnam
French National Agency for Research on AIDS and Viral Hepatitis
NCT00972699 COMPLETED Mentor Mothers: A Sustainable Family Intervention in South African Townships
University of California, Los Angeles
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