TheraRadar
Data updated: May 26, 2026

ACCRUFER (ferric maltol)

Trial Activity: Declining
Other Approved 2019-07-25

ACCRUFER is indicated for the treatment of Iron Deficiency.

Source: FDA Label • SHIELD TX

Development Insights

Shield Therapeutics conducting 4 trials (100%)
8 indications explored (Moderate)
iron-deficiency (2 trials)
anemia (1 trials)
iron deficiency, anaemia in children (1 trials)
2
Indications
--
Phase 3 Trials
1
Priority Reviews
6
Years on Market

Details

Status
Prescription
First Approved
2019-07-25
Patent Cliff
2035

Pro Metrics

Patent cliff and revenue data

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Routes
ORAL
Dosage Forms
CAPSULE

Companies

Active Ingredient: FERRIC MALTOL

ACCRUFER Approval History

2020
2021
2022
2023
2024
2025
2026
Original
New Indication
New Form
Label Update
6 FDA actions from 2019 to 2025 · 1 indication expansions
Dec 2025 SUPPL Priority
Efficacy
Sep 2022 SUPPL
Label · Labeling
Jun 2022 SUPPL
Label · Labeling

What ACCRUFER Treats

1 indications

ACCRUFER is approved for 1 conditions since its original approval in 2019. These indications span multiple therapeutic areas including oncology, immunology, and more.

  • Iron Deficiency
Source: FDA Label

ACCRUFER Competitive Set

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Three rings of competition based on shared molecular targets and treated indications.

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Filters applied: drops same-active-ingredient (505(b)(2) reformulations), route-mismatch (topical vs systemic), and cross-therapeutic-area matches in same-indication rings.

Drugs Similar to ACCRUFER

FDA-approved drugs for similar conditions. Compare mechanisms and indications to understand treatment alternatives.

INFED
IRON DEXTRAN
1 shared
AbbVie
Shared indications:
Iron Deficiency
INJECTAFER
FERRIC CARBOXYMALTOSE
1 shared
AM REGENT
Shared indications:
Iron Deficiency
📋

Clinical Trial Registry

4 trials
Trial Sponsor ID Phase Status Title
NCT05126901 FORTIS results posted ST10-01-305 Ph 3 completed Evaluate the Safety and Efficacy of Ferric Maltol Oral Suspension vs. Ferrous Sulfate Oral Liquid in Children and Adolescents Aged 2 to 17 Years With Iron-deficiency Anaemia, With a Single Arm Study in Infants Aged 1 Month to Less Than 2 Years
NCT03181451 results posted ST10-01-103 Ph 1 completed Evaluate the PK, Safety, Tolerability of Ferric Maltol at 3 Dosage Levels in Paediatric Subjects With Iron Deficiency
NCT02680756 results posted ST10-01-304 Ph 3 completed Safety and Efficacy Study of Oral Ferric Maltol Compared to Intravenous Iron To Treat Iron Deficiency Anaemia in IBD
NCT02968368 AEGIS-CKD results posted ST10-01-303 Ph 3 completed Study With Oral Ferric Maltol for the Treatment of Iron Deficiency Anemia in Subjects With Chronic Kidney Disease
🔬

Active Pipeline

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Key Completed Trials

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Completed studies with published results, ranked by significance

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

ACCRUFER FDA Label Details

Indications & Usage

FDA Label (PDF)

ACCRUFER is indicated for the treatment of Iron Deficiency.

View full patent landscape →
3 OB patents · 3 families · 69 international docs across 20 countries

ACCRUFER Patents & Exclusivity

Latest Patent: Oct 2035
Exclusivity: Dec 2028

Patents (3 active)

US9802973 Expires Oct 23, 2035
US10179120 Expires Jan 6, 2035
US9248148 Expires Mar 29, 2031

Exclusivity

NPP Until Dec 2028
Source: FDA Orange Book

Pro Intelligence Preview

Deep insights for ACCRUFER

Revenue Insights

  • Quarterly revenue tracking
  • Historical trend analysis

Patent Timeline

  • Cliff: 2035
  • 3 active patents

Trial Analysis

  • 4 total trials
  • Stage: Declining

Competitive Landscape

  • 2 similar drugs
  • Same target/indication analysis
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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.

How We Calculate These Metrics

Trial Activity Stage

Measures the current development activity pattern based on trial phases, status, and trends. Important: This measures R&D activity, not commercial lifecycle.

Trial statuses: "Active" means recruiting or ongoing. "Completed" means reached planned endpoint. "Terminated" means stopped early—often due to safety, efficacy, or business reasons.

  • Growth: High proportion of early-phase trials (Phase 1/2), active development
  • Expansion: Significant Phase 3 activity, approaching or pursuing approvals
  • Mature: Substantial Phase 4 post-marketing studies
  • Stable: Mixed phase distribution, steady development
  • Declining: Low active trial ratio, reduced R&D investment