TheraRadar
Data updated: May 26, 2026

ANTIVERT (meclizine hydrochloride)

CNS Approved 1957-02-14

ANTIVERT is indicated for the treatment of Nausea; Vomiting; Dizziness; Motion Sickness.

Source: FDA Label • CASPER PHARMA LLC
Jump to: Indications Approvals Trials Competitors Similar Safety Patents
3
Indications
--
Phase 3 Trials
69
Years on Market

Details

Status
Prescription
First Approved
1957-02-14
Routes
ORAL
Dosage Forms
TABLET, TABLET, CHEWABLE

Companies

CASPER PHARMA LLC
Active Ingredient: MECLIZINE HYDROCHLORIDE

ANTIVERT Approval History

1958
1959
1960
1961
1962
1963
1964
1965
1966
1967
1968
1969
1970
1971
1972
1973
1974
1975
1976
1977
1978
1979
1980
1981
1982
1983
1984
1985
1986
1987
1988
1989
1990
1991
1992
1993
1994
1995
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
Original
New Indication
New Form
Label Update
40 FDA actions from 1957 to 2019 · 2 indication expansions
Jun 2019 SUPPL
Efficacy
FDA Letter Label
Dec 2018 SUPPL
Label · Labeling
FDA Letter Label
Apr 2018 SUPPL
Efficacy
FDA Letter Label

What ANTIVERT Treats

4 indications

ANTIVERT is approved for 4 conditions since its original approval in 1957. These indications span multiple therapeutic areas including oncology, immunology, and more.

  • Nausea
  • Vomiting
  • Dizziness
  • Motion Sickness
Source: FDA Label

ANTIVERT Competitive Set

Pro

Three rings of competition based on shared molecular targets and treated indications.

Indication competitors

10

Same indication, different mechanism — what else might this patient receive?

FOCINVEZ
STERISCIENCE
2023 2 indic.
APONVIE
HERON THERAPS
2022 2 indic.
Unlock 8 more competitors across all three rings.
Upgrade to Pro

Filters applied: drops same-active-ingredient (505(b)(2) reformulations), route-mismatch (topical vs systemic), and cross-therapeutic-area matches in same-indication rings.

Drugs Similar to ANTIVERT

3 of 20

FDA-approved drugs for similar conditions. Compare mechanisms and indications to understand treatment alternatives.

PROMETHAZINE HYDROCHLORIDE; CODEINE PHOSPHATE
PROMETHAZINE HYDROCHLORIDE
3 shared
CHARTWELL RX
Shared indications:
NauseaVomitingMotion Sickness
PROMETHAZINE HYDROCHLORIDE; DEXTROMETHORPHAN HYDROBROMIDE
PROMETHAZINE HYDROCHLORIDE
3 shared
COSETTE
Shared indications:
NauseaVomitingMotion Sickness
PROMETHAZINE PLAIN
PROMETHAZINE HYDROCHLORIDE
3 shared
PHARMOBEDIENT
Shared indications:
NauseaVomitingMotion Sickness
View all 20 similar drugs Pro
🔬

Active Pipeline

Pro

Ongoing clinical trials by development phase

Loading...
⭐

Key Completed Trials

Pro

Completed studies with published results, ranked by significance

Loading...
📊

Trial Timeline

ClinicalTrials.gov ↗ Pro

Full development history with FDA approval milestones

|
Loading...
Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

ANTIVERT FDA Label Details

Indications & Usage

FDA Label (PDF)

ANTIVERT is indicated for the treatment of Nausea; Vomiting; Dizziness; Motion Sickness.

Track ANTIVERT with TheraRadar Pro

Watchlist alerts, full database access, CSV exports across 14,000+ drugs.

Upgrade to Pro

Data Sources

FDA Approval: NDA010721 → Label: DailyMed → Patents: FDA Orange Book → Trials: ClinicalTrials.gov →

Data sourced from official FDA and NIH databases. Click links to verify on original sources.