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Data updated: Sep 20, 2026

CALCIUM GLUCONATE IN SODIUM CHLORIDE (calcium gluconate) · HQ SPCLT PHARMA

Trial Activity: Expansion 3 active trials
Other Approved 2017-06-15

Calcium Gluconate in Sodium Chloride Injection is indicated for pediatric and adult patients for the treatment of acute symptomatic hypocalcemia. Limitations of Use The safety of Calcium Gluconate in Sodium Chloride Injection for long term use has not been established.

Development Insights

Jason Sperry conducting 1 trials (11%)
18 indications explored (Broad Platform)
trauma (3 trials)
hemorrhage (2 trials)
hypocalcemia (2 trials)
5
Indications
--
Phase 3 Trials
9
Years on Market

Details

Status
Prescription
First Approved
2017-06-15
Patent Cliff
2037

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Routes
INTRAVENOUS
Dosage Forms
SOLUTION

CALCIUM GLUCONATE IN SODIUM CHLORIDE Approval History

2018
2019
2020
2021
2022
2023
2024
2025
2026
Original
New Indication
New Form
Label Update
24 FDA actions from 2017 to 2026
Aug 2026 ORIGINAL
Update
Dec 2025 ORIGINAL
Update
Jun 2025 SUPPL
Label · Labeling

What CALCIUM GLUCONATE IN SODIUM CHLORIDE Treats

1 indications

CALCIUM GLUCONATE IN SODIUM CHLORIDE is approved for 1 conditions since its original approval in 2017. These indications span multiple therapeutic areas including oncology, immunology, and more.

  • Hypocalcemia

Same approved indications as CALCIUM GLUCONATE (same active ingredient).

Source: FDA Label
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Clinical Trial Registry

9 trials
Trial Sponsor ID Phase Status Title
NCT05958342 CAVALIER STUDY23040043 W81XWH-6-D-0024 Ph 2 recruiting CAlcium and VAsopressin Following Injury Early Resuscitation (CAVALIER) Trial
NCT05953376 3115 Ph 3 withdrawn Empiric Calcium in Massive Transfusion
NCT07217899 HUM00259931 Ph 2 recruiting Prophylactic Intravenous Calcium Gluconate to Decrease Blood Loss at Time of Cesarean Delivery in Pregnant Patients at High Risk for Uterine Atony
NCT06820645 CALM 15231 Ph 2, Ph 3 not yet recruiting Calcium Administration in Life-saving Management During Massive Hemorrhage
NCT01099449 results posted N08CB NCCTG-N08CB, CDR0000669660 Ph 3 completed Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity in Patients With Colon Cancer or Rectal Cancer Receiving Oxaliplatin-Based Combination Chemotherapy
NCT04958044 eCaEP2021 Ph 1 completed Endoscopic Assisted Calcium Electroporation in Esophageal Cancer
NCT02875587 Cabergoline/calcium gluconate Ph 2 completed Cabergoline Versus Calcium Gluconate Infusion in the Prevention of Ovarian Hyperstimulation Syndrome
NCT03473613 Ashraf Elmantwe 1 Ph 3 completed Cabergoline Versus Calcium Infusion in Ovarian Hyperstimulation Syndrome Prevention
NCT00998738 results posted RC08CC NCI-2009-01229, RC08CC Ph 3 terminated Calcium and Magnesium in Preventing Peripheral Neuropathy Caused by Ixabepilone in Patients With Breast Cancer
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Active Pipeline

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Ongoing clinical trials by development phase

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Key Completed Trials

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Completed studies with published results, ranked by significance

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

CALCIUM GLUCONATE IN SODIUM CHLORIDE FDA Label Details

Indications & Usage

FDA Label (PDF)

Calcium Gluconate in Sodium Chloride Injection is indicated for pediatric and adult patients for the treatment of acute symptomatic hypocalcemia. Limitations of Use The safety of Calcium Gluconate in Sodium Chloride Injection for long term use has not been established. • Calcium Gluconate in Sodium Chloride Injection is a form of calcium indicated for pediatric and adult patients for the treatment of acute symptomatic hypocalcemia. • Limitations of Use: The safety of Calcium Gluconate Injection for long term use has not been established.

View full patent landscape →
2 OB patents · 1 families · 3 international docs across 1 countries

CALCIUM GLUCONATE IN SODIUM CHLORIDE Patents & Exclusivity

Latest Patent: Jul 2037

Patents (2 active)

US10130646 Expires Jul 25, 2037
US10342813 Expires Jul 25, 2037
Source: FDA Orange Book

Pro Intelligence Preview

Deep insights for CALCIUM GLUCONATE IN SODIUM CHLORIDE

Revenue Insights

  • Quarterly revenue tracking
  • Historical trend analysis

Patent Timeline

  • Cliff: 2037
  • 22 active patents

Trial Analysis

  • 9 total trials
  • Stage: Expansion

Competitive Landscape

  • Competitor tracking
  • Same target/indication analysis
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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.

How We Calculate These Metrics

Trial Activity Stage

Measures the current development activity pattern based on trial phases, status, and trends. Important: This measures R&D activity, not commercial lifecycle.

Trial statuses: "Active" means recruiting or ongoing. "Completed" means reached planned endpoint. "Terminated" means stopped early—often due to safety, efficacy, or business reasons.

  • Growth: High proportion of early-phase trials (Phase 1/2), active development
  • Expansion: Significant Phase 3 activity, approaching or pursuing approvals
  • Mature: Substantial Phase 4 post-marketing studies
  • Stable: Mixed phase distribution, steady development
  • Declining: Low active trial ratio, reduced R&D investment