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Data updated: May 26, 2026

DICYCLOMINE HYDROCHLORIDE (PRESERVATIVE FREE) (dicyclomine hydrochloride)

Gastrointestinal Approved 2003-06-30

Dicyclomine hydrochloride helps patients with functional bowel and irritable bowel syndrome. This medication acts as an antispasmodic and anticholinergic agent to manage gastrointestinal distress. It is used to provide relief from smooth muscle spasms within the digestive tract.

Source: FDA Label • Hikma

How DICYCLOMINE HYDROCHLORIDE (PRESERVATIVE FREE) Works

This drug works by relieving smooth muscle spasms in the gastrointestinal tract using a dual mechanism. It targets acetylcholine-receptor sites to produce an anticholinergic effect and acts directly on the smooth muscle to block spasms caused by bradykinin and histamine.

Source: FDA Label
1
Indication
--
Phase 3 Trials
22
Years on Market

Details

Status
Prescription
First Approved
2003-06-30
Routes
INJECTION
Dosage Forms
INJECTABLE

Companies

Active Ingredient: DICYCLOMINE HYDROCHLORIDE

DICYCLOMINE HYDROCHLORIDE (PRESERVATIVE FREE) Approval History

2004
2005
2006
2007
2008
2009
2010
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
Original
New Indication
New Form
Label Update
5 FDA actions from 2003 to 2018
May 2018 SUPPL
Label · Labeling
May 2012 SUPPL
Label · Labeling
Oct 2007 SUPPL
Label · Labeling

What DICYCLOMINE HYDROCHLORIDE (PRESERVATIVE FREE) Treats

1 indications

DICYCLOMINE HYDROCHLORIDE (PRESERVATIVE FREE) is approved for 1 conditions since its original approval in 2003. These indications span multiple therapeutic areas including oncology, immunology, and more.

  • Irritable Bowel Syndrome
Source: FDA Label

DICYCLOMINE HYDROCHLORIDE (PRESERVATIVE FREE) Competitive Set

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Active Pipeline

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Key Completed Trials

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

DICYCLOMINE HYDROCHLORIDE (PRESERVATIVE FREE) FDA Label Details

Indications & Usage

DICYCLOMINE HYDROCHLORIDE (PRESERVATIVE FREE) is indicated for the treatment of Irritable Bowel Syndrome.

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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.