TheraRadar
Data updated: Jul 17, 2026

DIMETHYL SULFOXIDE · STIRA

Urology Approved 1978-04-04

DIMETHYL SULFOXIDE is FDA-approved to treat 1 condition (same as RIMSO-50).

Source: FDA Label
2
Indications
--
Phase 3 Trials
48
Years on Market

Details

Status
Prescription
First Approved
1978-04-04
Routes
INTRAVESICAL
Dosage Forms
SOLUTION

Companies

Active Ingredient: DIMETHYL SULFOXIDE

DIMETHYL SULFOXIDE Approval History

2003
2004
2005
2006
2007
2008
2009
2010
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
Original
New Indication
New Form
Label Update
2 FDA actions from 2002 to 2026
Jul 2026 ORIGINAL
Update
Nov 2002 ORIGINAL
Update

What DIMETHYL SULFOXIDE Treats

1 indications

DIMETHYL SULFOXIDE is approved for 1 conditions since its original approval in 2002. These indications span multiple therapeutic areas including oncology, immunology, and more.

  • Interstitial Cystitis

Same approved indications as RIMSO-50 (same active ingredient).

Source: FDA Label
📋

Clinical Trial Registry

1 trials
Trial Sponsor ID Phase Status Title
NCT03716583 MELADERM 2018-001705-91 Ph 2 completed Melatonin Cream Against Acute Radiation Dermatitis in Patients With Early Breast Cancer
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Active Pipeline

Pro

Ongoing clinical trials by development phase

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Key Completed Trials

Pro

Completed studies with published results, ranked by significance

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

DIMETHYL SULFOXIDE FDA Label Details

Indications & Usage

DIMETHYL SULFOXIDE is FDA-approved to treat 1 condition — same approved indications as RIMSO-50.

Looking for the branded version?

RIMSO-50

Full clinical data, patents, trials, and competitive landscape for dimethyl sulfoxide.

See RIMSO-50

Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.