ELETRIPTAN HYDROBROMIDE
Eletriptan hydrobromide is a serotonin (5-HT 1B/1D) receptor agonist indicated for the acute treatment of migraine with or without aura in adults. The medication is intended for use only after a clear diagnosis of migraine has been established and is not indicated for the preventive treatment of migraines or for cluster headaches. If a patient does not respond to the initial treatment, the diagnosis should be reconsidered before further administration. It serves as a targeted therapy for managing active migraine attacks rather than a prophylactic measure.
How ELETRIPTAN HYDROBROMIDE Works
Eletriptan hydrobromide functions by binding with high affinity to 5-HT 1B, 5-HT 1D, and 5-HT 1F receptors. Its therapeutic effect is attributed to agonist activity at the 5-HT 1B/1D receptors located on intracranial blood vessels and sensory nerves of the trigeminal system. This activation leads to the constriction of cranial vessels and inhibits the release of pro-inflammatory neuropeptides that contribute to migraine symptoms. By addressing the local cranial vasodilatation and nerve signaling associated with the condition, the drug alleviates the migraine headache.
Details
- Status
- Prescription
- First Approved
- 2017-06-16
- Routes
- ORAL
- Dosage Forms
- TABLET
Companies
ELETRIPTAN HYDROBROMIDE Approval History
What ELETRIPTAN HYDROBROMIDE Treats
2 indicationsELETRIPTAN HYDROBROMIDE is approved for 2 conditions since its original approval in 2017. These indications span multiple therapeutic areas including oncology, immunology, and more.
- Migraine
- Cluster Headache
ELETRIPTAN HYDROBROMIDE Competitive Set
ProThree rings of competition based on shared molecular targets and treated indications.
Direct competitors
Same target(s) AND same indication — head-to-head.
Indication competitors
Same indication, different mechanism — what else might this patient receive?
Filters applied: drops same-active-ingredient (505(b)(2) reformulations), route-mismatch (topical vs systemic), and cross-therapeutic-area matches in same-indication rings.
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Active Pipeline
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Key Completed Trials
Completed studies with published results, ranked by significance
Trial Timeline
Full development history with FDA approval milestones
Understanding FDA Approval Types
| Count | Type | What it means |
|---|---|---|
| - | ORIG | Original approval - drug first enters market |
| - | SUPPL - Efficacy | New indication (new disease/condition approved) |
| - | SUPPL - Labeling | Label text changes (warnings, dosing updates) |
| - | SUPPL - Manufacturing | Production changes (new facility) |
| - | SUPPL - Chemistry | Formulation changes (new dosage strength) |
Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.
ELETRIPTAN HYDROBROMIDE FDA Label Details
Indications & Usage
ELETRIPTAN HYDROBROMIDE is indicated for the treatment of Migraine; Cluster Headache.
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RELPAX
Full clinical data, patents, trials, and competitive landscape for eletriptan hydrobromide.
Data Sources
Data sourced from official FDA and NIH databases. Click links to verify on original sources.