TheraRadar
Data updated: May 26, 2026

EMOQUETTE (desogestrel)

Trial Activity: Declining
Women's Health Approved 2011-02-25

Development Insights

Children's Hospital Los Angeles conducting 1 trials (33%)
3 indications explored (Focused)
congenital central hypoventilation syndrome (1 trials)
uterine leiomyoma (1 trials)
ondine syndrome (1 trials)
1
Indication
--
Phase 3 Trials
15
Years on Market

Details

Status
Discontinued
First Approved
2011-02-25
Routes
ORAL-28
Dosage Forms
TABLET

Companies

Active Ingredient: DESOGESTREL , ETHINYL ESTRADIOL

EMOQUETTE Approval History

2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
Original
New Indication
New Form
Label Update
7 FDA actions from 2011 to 2022
Apr 2022 SUPPL
Label · Labeling
Mar 2022 SUPPL
Label · Labeling
Aug 2017 SUPPL
Label · Labeling

What EMOQUETTE Treats

1 FDA approvals

Originally approved for its first indication in 2011 .

  • Other (1)
📋

Clinical Trial Registry

3 trials
Trial Sponsor ID Phase Status Title
NCT01500473 results posted CCI-11-00057 Ph 2 terminated Therapeutic Effect of Desogestrel on Ventilatory Control in Patients With Congenital Central Hypoventilation Syndrome
NCT01738724 FMRPUSP-UROGIN-002 Ph 4 terminated Study of the Efficacy of Dienogest in the Treatment of Uterine Leiomyomas When Compared to Desogestrel and Goserelin
NCT01243697 RESPIRONDINE P101001 Ph 2, Ph 3 completed Assessment of Desogestrel in Ondine Syndrome
🔬

Active Pipeline

Pro

Ongoing clinical trials by development phase

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Key Completed Trials

Pro

Completed studies with published results, ranked by significance

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📊

Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

EMOQUETTE FDA Label Details

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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.

How We Calculate These Metrics

Trial Activity Stage

Measures the current development activity pattern based on trial phases, status, and trends. Important: This measures R&D activity, not commercial lifecycle.

Trial statuses: "Active" means recruiting or ongoing. "Completed" means reached planned endpoint. "Terminated" means stopped early—often due to safety, efficacy, or business reasons.

  • Growth: High proportion of early-phase trials (Phase 1/2), active development
  • Expansion: Significant Phase 3 activity, approaching or pursuing approvals
  • Mature: Substantial Phase 4 post-marketing studies
  • Stable: Mixed phase distribution, steady development
  • Declining: Low active trial ratio, reduced R&D investment