TheraRadar
Data updated: May 26, 2026

ESKATA (hydrogen peroxide)

Trial Activity: Declining 1 active trials
Dermatology Approved 2017-12-14

Development Insights

Institute of Cancer Research, United Kingdom conducting 2 trials (33%)
5 indications explored (Moderate)
breast cancer (2 trials)
tooth whitening (2 trials)
covid19 (1 trials)
1
Indication
--
Phase 3 Trials
8
Years on Market

Details

Status
Discontinued
First Approved
2017-12-14
Patent Cliff
2035

Pro Metrics

Patent cliff and revenue data

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Routes
TOPICAL
Dosage Forms
SOLUTION

Companies

Active Ingredient: HYDROGEN PEROXIDE

ESKATA Approval History

2018
2019
2020
2021
2022
2023
2024
2025
2026
Original
New Indication
New Form
Label Update
2 FDA actions from 2017 to 2019
Feb 2019 SUPPL
Label · Labeling
Dec 2017 ORIGINAL
Update · Type 5 - New Formulation or New Manufacturer

What ESKATA Treats

1 FDA approvals

Originally approved for its first indication in 2017 .

  • Other (1)
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Clinical Trial Registry

6 trials
Trial Sponsor ID Phase Status Title
NCT03946202 CCR5119 2019-001709-25 Ph 2 recruiting KORTUC Phase II - Intra-tumoural Radiation Sensitizer in Patients With Locally Advanced/Recurrent Breast Cancer
NCT04659928 results posted HSC-DB-20-1017 Ph 4 completed Evaluation of Aerosol in a Dental Clinic
NCT02757651 CCR4502 Ph 1, Ph 2 completed KORTUC: Intra-tumoural Hydrogen Peroxide as a Radiation Sensitizer in Patients With Locally Advanced/Recurrent Breast Cancer in Terms of Toxicity and Tumour Response
NCT03536637 DMT310-001 Ph 2 completed DMT310-001 Topical in the Treatment of Acne Vulgaris
NCT03019224 104/2015 Ph 4 completed Effects of Desensitizing Dentifrices on the Reduction of Pain Sensitivity Caused by In-office Dental Whitening
NCT00978861 REMEWHITE RE5 Ph 3 completed Clinical Study to Evaluate of The Whitening Efficacy and Safety of REMEWHITE
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Active Pipeline

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Ongoing clinical trials by development phase

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Key Completed Trials

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Completed studies with published results, ranked by significance

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

ESKATA FDA Label Details

View full patent landscape →
5 OB patents · 1 families · 41 international docs across 17 countries

ESKATA Patents & Exclusivity

Latest Patent: Jul 2035

Patents (5 active)

US9675639 Expires Jul 4, 2035
US10098910 Expires Apr 21, 2035
US9980983 Expires Apr 21, 2035
US10493103 Expires Apr 21, 2035
US10729720 Expires Apr 21, 2035
Source: FDA Orange Book

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Deep insights for ESKATA

Revenue Insights

  • Quarterly revenue tracking
  • Historical trend analysis

Patent Timeline

  • Cliff: 2035
  • 5 active patents

Trial Analysis

  • 6 total trials
  • Stage: Declining

Competitive Landscape

  • Competitor tracking
  • Same target/indication analysis
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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.

How We Calculate These Metrics

Trial Activity Stage

Measures the current development activity pattern based on trial phases, status, and trends. Important: This measures R&D activity, not commercial lifecycle.

Trial statuses: "Active" means recruiting or ongoing. "Completed" means reached planned endpoint. "Terminated" means stopped early—often due to safety, efficacy, or business reasons.

  • Growth: High proportion of early-phase trials (Phase 1/2), active development
  • Expansion: Significant Phase 3 activity, approaching or pursuing approvals
  • Mature: Substantial Phase 4 post-marketing studies
  • Stable: Mixed phase distribution, steady development
  • Declining: Low active trial ratio, reduced R&D investment