TheraRadar
Data updated: May 26, 2026

EZALLOR SPRINKLE (rosuvastatin calcium)

Trial Activity: Stable 2 active trials
Metabolic Approved 2018-12-18

Development Insights

AstraZeneca conducting 4 trials (44%)
13 indications explored (Broad Platform)
familial hypercholesterolaemia (3 trials)
spinal cord injuries (1 trials)
osteoporosis (1 trials)
2
Indications
--
Phase 3 Trials
7
Years on Market

Details

Status
Discontinued
First Approved
2018-12-18
Patent Cliff
2036

Pro Metrics

Patent cliff and revenue data

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Routes
ORAL
Dosage Forms
CAPSULE

Companies

Active Ingredient: ROSUVASTATIN CALCIUM

EZALLOR SPRINKLE Approval History

2019
2020
2021
2022
2023
2024
2025
2026
Original
New Indication
New Form
Label Update
48 FDA actions from 2018 to 2025 · 1 indication expansions
Feb 2025 SUPPL
Label · Labeling
Mar 2024 SUPPL
Label · Labeling
Aug 2023 SUPPL
Efficacy

What EZALLOR SPRINKLE Treats

2 FDA approvals

Originally approved for its first indication in 2018 . Covers 2 distinct patient populations.

  • Other (2)
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Clinical Trial Registry

7 trials
Trial Sponsor ID Phase Status Title
NCT03113994 RoBaCO 2016-350642 Ph 2 terminated Statin Monotherapy for Treatment of Endocrine Metabolic Disease Risk
NCT04319627 SAVER SAVER Trial Ph 3 recruiting Statins for Venous Event Reduction in Patients With Venous Thromboembolism
NCT04602754 EMS1019 - Berlim 25/20 Ph 3 recruiting Efficacy and Safety of Berlim 25/20 Association in the Treatment of Type II Diabetes Mellitus and Dyslipidemia.
NCT06081166 TA-8995-11 Ph 1 completed A Drug-drug Interaction Study Evaluating the PK Effects of Obicetrapib on Atorvastatin and Rosuvastatin
NCT05828303 CA127-1027 Ph 1 withdrawn A Phase 1 Study to Evaluate the Potential Drug Interactions Between Repotrectinib and Metformin, Digoxin, and Rosuvastatin in Patients With Advanced Solid Tumors
NCT01078675 results posted D3561C00002 Ph 3 completed An Study to Evaluate Rosuvastatin in Children and Adolescents With Familial Hypercholesterolaemia
NCT00766025 D3560C00059 Rosuvastatin Calcium Ph 1 completed Study in Taiwanese Subjects Identified as CYP2C19 Poor and Extensive Metabolizers Receiving Rosuvastatin
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Active Pipeline

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Ongoing clinical trials by development phase

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Key Completed Trials

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Completed studies with published results, ranked by significance

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

EZALLOR SPRINKLE FDA Label Details

View full patent landscape →
1 OB patents · 1 families · 12 international docs across 4 countries

EZALLOR SPRINKLE Patents & Exclusivity

Latest Patent: Feb 2036

Patents (1 active)

US10413543 Expires Feb 12, 2036
Source: FDA Orange Book

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Deep insights for EZALLOR SPRINKLE

Revenue Insights

  • Quarterly revenue tracking
  • Historical trend analysis

Patent Timeline

  • Cliff: 2036
  • 16 active patents

Trial Analysis

  • 9 total trials
  • Stage: Stable

Competitive Landscape

  • Competitor tracking
  • Same target/indication analysis
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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.

How We Calculate These Metrics

Trial Activity Stage

Measures the current development activity pattern based on trial phases, status, and trends. Important: This measures R&D activity, not commercial lifecycle.

Trial statuses: "Active" means recruiting or ongoing. "Completed" means reached planned endpoint. "Terminated" means stopped early—often due to safety, efficacy, or business reasons.

  • Growth: High proportion of early-phase trials (Phase 1/2), active development
  • Expansion: Significant Phase 3 activity, approaching or pursuing approvals
  • Mature: Substantial Phase 4 post-marketing studies
  • Stable: Mixed phase distribution, steady development
  • Declining: Low active trial ratio, reduced R&D investment