TheraRadar
Data updated: May 26, 2026

FLONASE SENSIMIST ALLERGY RELIEF (fluticasone furoate)

Respiratory Approved 2007-04-27
3
Indications
--
Phase 3 Trials
19
Years on Market

Details

Status
Over-the-counter
First Approved
2007-04-27
Patent Cliff
2028

Pro Metrics

Patent cliff and revenue data

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Routes
NASAL
Dosage Forms
SPRAY, METERED

Companies

Active Ingredient: FLUTICASONE FUROATE

FLONASE SENSIMIST ALLERGY RELIEF Approval History

2008
2009
2010
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
Original
New Indication
New Form
Label Update
14 FDA actions from 2007 to 2025 · 2 indication expansions
Dec 2025 SUPPL
Label · Labeling
Sep 2025 SUPPL
Label · Labeling
Jan 2025 SUPPL
Label · Labeling

What FLONASE SENSIMIST ALLERGY RELIEF Treats

3 FDA approvals

Originally approved for its first indication in 2007 . Covers 3 distinct patient populations.

  • Other (3)
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Clinical Trial Registry

25 trials
Trial Sponsor ID Phase Status Title
NCT02889809 results posted 114971 Ph 4 completed Effects of a Orally Inhaled Fluticasone Furoate on Growth Velocity in Prepubertal, Paediatric Subjects With Asthma Over a Year
NCT03012061 results posted 205832 2016-002843-40 Ph 2 completed Phase IIb Study of Umeclidinium (UMEC) Bromide Versus Placebo in Subjects With Asthma
NCT03898466 Bio ID 366 Ph 4 completed Effect of Fluticasone Furoate on Methacholine Challenge
NCT02446418 results posted 116492 Ph 3 completed A Study to Compare the Efficacy of Fluticasone Furoate/Vilanterol Inhalation Powder With Usual Inhaled Corticosteroids (ICS)/Long Acting Beta Agonists (LABA) in Persistent Asthma
NCT03315000 VIL-2017 Ph 4 completed Effect of Vilanterol on Methacholine Challenge Results
NCT01313676 results posted 113782 Ph 3 completed Study to Evaluate the Effect of Fluticasone Furoate/Vilanterol on Survival in Subjects With Chronic Obstructive Pulmonary Disease
NCT03363191 206962 Ph 4 withdrawn The Efficacy of Fluticasone Furoate/Vilanterol Versus (vs) Fluticasone Furoate on Asthma
NCT01086384 results posted 106837 Ph 3 completed Asthma Exacerbation Study
NCT02502734 results posted 107112 Ph 3 completed Effect of Inhaled Fluticasone Furoate on Short-term Growth in Paediatric Subjects With Asthma
NCT01159912 results posted 112059 Ph 3 completed Evaluating the Efficacy and Safety of Fluticasone Furoate Inhalation Powder in the Treatment of Asthma in Adults and Adolescents
NCT01013701 results posted NA_00029405 Ph 4 terminated Compare the Effects of Fluticasone Furoate Nasal Spray vs Placebo in Patients With Nasal Polypoid Disease
NCT01000597 113477 Ph 1 completed Study to Look at and Compare How Inhaled and Intravenous Fluticasone Furoate is Processed by the Body in Healthy Caucasian, Japanese, Korean and Chinese Subjects
NCT01299558 102934 Ph 1 completed Study to Look at and Compare How Inhaled and Intravenous Fluticasone Furoate and GW642444 Are Processed by the Body in Healthy Subjects
NCT01563029 results posted 106855 Ph 2 completed A Dose-ranging Study of Fluticasone Furoate (FF)
NCT02064504 201010 Ph 1 completed Study to Determine the Pharmacokinetics of GSK961081 and Fluticasone Furoate When Administered Alone or in Combination
NCT01332292 results posted 102942 Ph 2 completed Pharmacokinetics and PharmacoDynamics of GW685698 in Paedeatric Asthmatic Patients
NCT01128569 results posted 113090 Ph 2 completed Randomised Study Comparing the Effects of Inhaled Fluticasone Furoate (FF)/Vilanterol (VI; GW642444M) Combination and FF on an Allergen Induced Asthmatic Response
NCT01128595 results posted 113126 Ph 2 completed Randomised Study Comparing the Effects of Inhaled FF/GW642444M Combination, FF and GW642444M on an Allergen Induced Asthmatic Response
NCT01453023 results posted 112777 Ph 2 completed Inhaled Fluticasone Furoate/Vilanterol Safety and Tolerability, PK and PD Study
NCT01630135 results posted 116364 Ph 3 completed Study FFR116364, a Placebo-controlled Study of GW685698X in Paediatric Subjects With Perennial Allergic Rhinitis
NCT01622231 results posted 116365 Ph 3 completed Study FFR116365, an Open-label Study of GW685698X in Paediatric Subjects With Perennial Allergic Rhinitis
NCT01431950 results posted 114496 Ph 3 completed Evaluating the Efficacy and Safety of Fluticasone Furoate in the Treatment of Asthma in Adults and Adolescents
NCT01691885 results posted 116601 Ph 3 completed RELOVAIR® Lung Deflation Study
NCT00603044 results posted 15868B 15868B Ph 4 completed Mechanism of Action of Fluticasone Furoate in Childhood Obstructive Sleep Apnea Syndrome
NCT00791973 results posted 16367B (OC 3) Ph 4 completed Effect of Veramyst on the Nasal and Ocular Symptoms of the Early Reaction to Nasal Challenge With Allergen
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Active Pipeline

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Key Completed Trials

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Completed studies with published results, ranked by significance

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

FLONASE SENSIMIST ALLERGY RELIEF FDA Label Details

View full patent landscape →
3 OB patents · 3 families · 102 international docs across 24 countries

FLONASE SENSIMIST ALLERGY RELIEF Patents & Exclusivity

Latest Patent: Oct 2028

Patents (3 active)

US8147461 Expires Oct 15, 2028
US8347879 Expires Jul 15, 2028
US8062264 Expires Apr 5, 2026
Source: FDA Orange Book

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Revenue Insights

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Patent Timeline

  • Cliff: 2028
  • 3 active patents

Trial Analysis

  • Clinical trial tracking
  • Development stage analysis

Competitive Landscape

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  • Same target/indication analysis
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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.