TheraRadar
Data updated: May 26, 2026

KYRA (drospirenone)

Women's Health Approved 2019-07-23
1
Indication
--
Phase 3 Trials
6
Years on Market

Details

Status
Discontinued
First Approved
2019-07-23
Routes
ORAL
Dosage Forms
TABLET

Companies

Active Ingredient: DROSPIRENONE , ETHINYL ESTRADIOL

KYRA Approval History

2020
2021
2022
2023
2024
2025
2026
Original
New Indication
New Form
Label Update
1 FDA actions from 2019 to 2019
Jul 2019 ORIGINAL
Update

What KYRA Treats

1 FDA approvals

Originally approved for its first indication in 2019 .

  • Other (1)
📋

Clinical Trial Registry

6 trials
Trial Sponsor ID Phase Status Title
NCT07340190 CDAK539A12102 2025-521000-22-00 Ph 1 not yet recruiting A Drug-drug Interaction Study to Evaluate the Effects of Pelabresib on the Pharmacokinetics of Repaglinide, Midazolam, and Combined Oral Contraceptive in Patients With Advanced Malignancies
NCT06345560 077766 Ph 1, Ph 2 recruiting Pharmacokinetics of Drospirenone Only Pills: A Pre- and Post-Bariatric Surgery Study
NCT07293728 STUDY00028768 Ph 4 not yet recruiting A Randomized Feasibility Trial Comparing Drospirenone and Norethindrone for Postpartum Hypertension Management in Preeclampsia
NCT05461573 CF113-303 Ph 3 completed Efficacy, Safety, and Tolerability of LPRI-CF113 as an Oral Contraceptive in Females
NCT05706753 CR109284 2022-002828-12, 70033093THR1009 Ph 1 completed A Study of Milvexian in Healthy Adult Females
NCT06039826 18533 J1I-MC-GZBV Ph 1 completed A Study of LY3437943 in Postmenopausal Female Participants Who Are Overweight or Obese
🔬

Active Pipeline

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Ongoing clinical trials by development phase

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Key Completed Trials

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Completed studies with published results, ranked by significance

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📊

Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

KYRA FDA Label Details

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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.