TheraRadar
Data updated: Sep 20, 2026

PERTOFRANE (desipramine hydrochloride) · Sanofi

CNS Approved 1968-04-10

PERTOFRANE is FDA-approved to treat 1 condition (same as DESIPRAMINE HYDROCHLORIDE).

Source: FDA Label
1
Indication
--
Phase 3 Trials
58
Years on Market

Details

Status
Discontinued
First Approved
1968-04-10
Routes
ORAL
Dosage Forms
CAPSULE

Companies

Active Ingredient: DESIPRAMINE HYDROCHLORIDE

PERTOFRANE Approval History

1969
1970
1971
1972
1973
1974
1975
1976
1977
1978
1979
1980
1981
1982
1983
1984
1985
1986
1987
1988
1989
1990
1991
1992
1993
1994
1995
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
Original
New Indication
New Form
Label Update
10 FDA actions from 1968 to 1985
Jul 1985 SUPPL
Label · Labeling
May 1984 SUPPL
Label · Labeling
Aug 1977 SUPPL
Label · Labeling

What PERTOFRANE Treats

1 indications

PERTOFRANE is approved for 1 conditions since its original approval in 1968. These indications span multiple therapeutic areas including oncology, immunology, and more.

  • Depression

Same approved indications as DESIPRAMINE HYDROCHLORIDE (same active ingredient).

Source: FDA Label
📋

Clinical Trial Registry

1 trials
Trial Sponsor ID Phase Status Title
NCT00964886 results posted NURA-019-09S Ph 2 completed Efficacy of Antidepressants in Chronic Back Pain
🔬

Active Pipeline

Pro

Ongoing clinical trials by development phase

Loading...

Key Completed Trials

Pro

Completed studies with published results, ranked by significance

Loading...
📊

Trial Timeline

Full development history with FDA approval milestones

|
Loading...
Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

PERTOFRANE FDA Label Details

Indications & Usage

PERTOFRANE is FDA-approved to treat 1 condition — same approved indications as DESIPRAMINE HYDROCHLORIDE.

Track PERTOFRANE with TheraRadar Pro

Watchlist alerts, full database access, CSV exports across 14,000+ drugs.

Upgrade to Pro

Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.