TheraRadar
Data updated: May 26, 2026

Prevnar 20 (pneumococcal 20-valent conjugate vaccine)

Approved 2021-06-07
1
Indication
--
Phase 3 Trials
4
Years on Market

Details

Status
Prescription
First Approved
2021-06-07
Patent Cliff
2033

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Patent cliff and revenue data

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Routes
Intramuscular
Dosage Forms
Injection

Companies

Prevnar 20 Approval History

2022
2023
2024
2025
2026
Original
New Indication
New Form
Label Update
1 FDA actions from 2021 to 2021
Jun 2021 ORIGINAL
Update · CBER biologic (Purple Book)

What Prevnar 20 Treats

1 FDA approvals

Originally approved for its first indication in 2021 .

  • Other (1)
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Clinical Trial Registry

7 trials
Trial Sponsor ID Phase Status Title
NCT07160244 C1091009 2022-503070-36-00 Ph 3 recruiting BEATRIX: A Study to Learn About a Group B Streptococcus Vaccine in Healthy Pregnant Women and Their Babies
NCT05183854 HCI145280 NCI-2021-13373, HCI145280 Ph 2 recruiting Pneumococcal Pneumonia Vaccine Series (PCV20 and PPSV23) in Patients With Chronic Lymphocytic Leukemia Associated Immunodeficiency, PROTECT CLL Trial
NCT03621670 results posted 205239 2016-003268-37, V72_57 Ph 3 completed Safety and Immunogenicity of GSK Meningococcal Group B Vaccine and 13-valent Pneumococcal Vaccine Administered Concomitantly With Routine Infant Vaccines to Healthy Infants
NCT05170399 10000444 000444-H Ph 4 recruiting Vaccine Responses in Patients With B Cell Malignancies
NCT05417165 OSU-21289 NCI-2022-01763 Ph 2 recruiting Anti-pneumococcal Vaccine Strategy in Patients With Chronic Lymphocytic Leukemia
NCT05412030 219651 2023-000423-36 Ph 2 completed A Phase 2 Study to Evaluate the Safety, Tolerability, and Immune Response of AFX3772 Vaccine in Healthy Infants
NCT05297578 results posted VAX24-102 Ph 2 completed Safety, Tolerability, and Immunogenicity Study of a 24-Valent Pneumococcal Conjugate Vaccine (VAX-24) in Older Adults
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Active Pipeline

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Ongoing clinical trials by development phase

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Key Completed Trials

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Completed studies with published results, ranked by significance

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📊

Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

Prevnar 20 FDA Label Details

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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.