TheraRadar
Data updated: May 26, 2026

Rotateq (rotavirus vaccine, live, oral, pentavalent)

Approved 2006-02-02
1
Indication
--
Phase 3 Trials
20
Years on Market

Details

Status
Prescription
First Approved
2006-02-02
Revenue
$771M (FY-2024)

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Routes
Oral
Dosage Forms
Suspension

Companies

Rotateq Approval History

2007
2008
2009
2010
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
Original
New Indication
New Form
Label Update
1 FDA actions from 2006 to 2006
Feb 2006 ORIGINAL
Update · CBER biologic (Purple Book)

What Rotateq Treats

1 FDA approvals

Originally approved for its first indication in 2006 .

  • Other (1)
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Clinical Trial Registry

12 trials
Trial Sponsor ID Phase Status Title
NCT06736041 PSK03 U1111-1294-7860 Ph 3 active not recruiting Study of a 4-Dose Regimen of a 21-valent Pneumococcal Conjugate Vaccine in Healthy Infants From Approximately 2 Months of Age
NCT06824194 PSK05 U1111-1295-5983 Ph 3 active not recruiting Study of the Safety of a 21-valent Pneumococcal Conjugate Vaccine in Healthy Infants From Approximately 2 Months of Age
NCT06824181 PSK00031 U1111-1294-7911 Ph 3 active not recruiting Study of Mixed Vaccination Schedules With a 21-valent Pneumococcal Conjugate Vaccine and a 20-valent Pneumococcal Conjugate Vaccine in Healthy Infants From Approximately 2 Months of Age
NCT04398706 results posted PSK00008 U1111-1238-1638, PSK00008 Ph 2 completed Study of a Pneumococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Toddlers and Infants
NCT03691610 results posted MET61 U1111-1205-2836, MET61 Ph 3 completed Immunogenicity and Safety Study of a Quadrivalent Meningococcal Conjugate Vaccine Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers
NCT00880698 results posted P1072 10638, IMPAACT P1072 Ph 2 completed Safety and Immune Response of a Rotavirus Vaccine in HIV-infected and Uninfected Children Born to HIV-infected Mothers
NCT01341639 results posted V419-007 2010-021490-37 Ph 3 completed Safety, Tolerability, and Immunogenicity of V419 in Healthy Infants When Given at 2, 3, 4 and 12 Months (V419-007)
NCT02193061 Rota/CeNSIA Ph 3 completed Randomized, Controlled Single-blind Clinical Study to Assess Vaccine Interchangeability Between RV5 and RV1 Using Seven Combined Anti-rotavirus Prevention Programs
NCT01839175 HXM01C 2012-005547-24 Ph 3 completed Concomitant Administration of a New Hexavalent Vaccine With a Meningococcal Serogroup C Conjugate Vaccine in Healthy Infants During Primary Series Immunisation Followed by Booster Vaccination
NCT00496054 results posted V260-021 2007_020 Ph 3 completed Safety,Tolerability and Immunogenicity of Vaccination With Rotateq in Healthy Infants in India (V260-021)
NCT00953056 results posted V260-028 2009_627 Ph 1 completed A Study of V260 in Healthy Chinese Adults, Children and Infants (V260-028)(COMPLETED)
NCT01003431 V260-036 V260-036 Ph 3 withdrawn A Study of the Immunogenicity and Safety of Whole-Cell Pertussis Containing Vaccine Administered Concomitantly With RotaTeq™ (V260) or Rotarix™ (V260-036)(WITHDRAWN)
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Active Pipeline

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Ongoing clinical trials by development phase

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Key Completed Trials

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Completed studies with published results, ranked by significance

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

Rotateq FDA Label Details

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Revenue Insights

  • FY-2024: $771M
  • Historical trend analysis

Patent Timeline

  • Patent expiration dates
  • Generic/biosimilar risk

Trial Analysis

  • Clinical trial tracking
  • Development stage analysis

Competitive Landscape

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  • Same target/indication analysis
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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.