TheraRadar
Data updated: May 26, 2026

SENSIPAR (cinacalcet hydrochloride)

Trial Activity: Declining
Renal Approved 2004-03-08

Development Insights

Kyowa Kirin Co., Ltd. conducting 1 trials (33%)
5 indications explored (Moderate)
secondary hyperparathyroidism (1 trials)
chronic kidney disease (1 trials)
hyperparathyroidism, secondary (1 trials)
4
Indications
--
Phase 3 Trials
1
Priority Reviews
22
Years on Market

Details

Status
Discontinued
First Approved
2004-03-08
Patent Cliff
2026
Revenue
$17M (Q3-2022)

Pro Metrics

Patent cliff and revenue data

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Routes
ORAL
Dosage Forms
TABLET

Companies

Active Ingredient: CINACALCET HYDROCHLORIDE

SENSIPAR Approval History

2005
2006
2007
2008
2009
2010
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
Original
New Indication
New Form
Label Update
48 FDA actions from 2004 to 2019 · 2 indication expansions
Dec 2019 SUPPL
Label · Labeling
Mar 2019 SUPPL
Label · Labeling
May 2017 SUPPL
Efficacy

What SENSIPAR Treats

4 FDA approvals

Originally approved for its first indication in 2004 . Covers 4 distinct patient populations.

  • Other (4)
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Clinical Trial Registry

3 trials
Trial Sponsor ID Phase Status Title
NCT03822507 7580-201 Ph 3 completed Study of KHK7580 in Subjects With Secondary Hyperparathyroidism in Asia
NCT01439867 results posted 20110100 2011-004618-40 Ph 2 terminated Safety & Tolerability of Cinacalcet in Pediatric Patients With Chronic Kidney Disease and Secondary Hyperparathyroidism
NCT01054079 results posted IRB00009741 NCI-2009-01514, CCCWFU 98309 Ph 2 completed Cinacalcet Hydrochloride in Treating Men With Recurrent Prostate Cancer
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Active Pipeline

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Ongoing clinical trials by development phase

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Key Completed Trials

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Completed studies with published results, ranked by significance

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

SENSIPAR FDA Label Details

View full patent landscape →
2 OB patents · 1 families · 116 international docs across 30 countries

SENSIPAR Patents & Exclusivity

Latest Patent: Sep 2026

Patents (2 active)

US7829595 Expires Sep 22, 2026
US9375405 Expires Sep 22, 2026
Source: FDA Orange Book

Pro Intelligence Preview

Deep insights for SENSIPAR

Revenue Insights

  • Q3-2022: $17M
  • Historical trend analysis

Patent Timeline

  • Cliff: 2026
  • 18 active patents

Trial Analysis

  • 3 total trials
  • Stage: Declining

Competitive Landscape

  • Competitor tracking
  • Same target/indication analysis
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Full approval history • All patents • Revenue trends • Competitor analysis

Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.

How We Calculate These Metrics

Trial Activity Stage

Measures the current development activity pattern based on trial phases, status, and trends. Important: This measures R&D activity, not commercial lifecycle.

Trial statuses: "Active" means recruiting or ongoing. "Completed" means reached planned endpoint. "Terminated" means stopped early—often due to safety, efficacy, or business reasons.

  • Growth: High proportion of early-phase trials (Phase 1/2), active development
  • Expansion: Significant Phase 3 activity, approaching or pursuing approvals
  • Mature: Substantial Phase 4 post-marketing studies
  • Stable: Mixed phase distribution, steady development
  • Declining: Low active trial ratio, reduced R&D investment