TheraRadar
Data updated: May 26, 2026

STEQEYMA (ustekinumab-stba)

Interleukin-12 Antagonists Genetically Validated
Immunology Approved 2024-12-17

STEQEYMA is a human interleukin-12 and -23 antagonist indicated for the treatment of: Adult patients with: moderate to severe plaque psoriasis (PsO) who are candidates for phototherapy or systemic therapy. active psoriatic arthritis (PsA) . moderately to severely active Crohn's disease (CD) . moderately to severely active ulcerative colitis. Pediatric patients 6 years and older with: moderate to severe plaque psoriasis (PsO), who are candidates for phototherapy or systemic therapy.

Source: FDA Label • CELLTRION, INC.
2
Indications
--
Phase 3 Trials
1
Years on Market

Details

Status
Prescription
First Approved
2024-12-17
Routes
SUBCUTANEOUS, INTRAVENOUS
Dosage Forms
INJECTABLE

Companies

Active Ingredient: USTEKINUMAB-STBA

STEQEYMA Approval History

2025
2026
Original
New Indication
New Form
Label Update
15 FDA actions from 2024 to 2025
Dec 2025 SUPPL
Label · Labeling
Jun 2025 SUPPL
Label · Labeling
Apr 2025 ORIGINAL
New Ingredient · Type 2 - New Active Ingredient

What STEQEYMA Treats

2 FDA approvals

Originally approved for its first indication in 2024 . Covers 2 distinct patient populations.

  • Other (2)

STEQEYMA Target & Pathway

Pro

Target

IL-12 (Interleukin 12) Cytokine

Auto-substitute OK for Stelara

Pharmacists can substitute STEQEYMA for Stelara without calling the prescriber. This is a lower-cost alternative with no clinically meaningful differences.

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Active Pipeline

Pro

Ongoing clinical trials by development phase

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Key Completed Trials

Pro

Completed studies with published results, ranked by significance

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

STEQEYMA FDA Label Details

Indications & Usage

FDA Label (PDF)

STEQEYMA is a human interleukin-12 and -23 antagonist indicated for the treatment of: Adult patients with: moderate to severe plaque psoriasis (PsO) who are candidates for phototherapy or systemic therapy. active psoriatic arthritis (PsA) . moderately to severely active Crohn's disease (CD) . moderately to severely active ulcerative colitis. Pediatric patients 6 years and older with: moderate to severe plaque psoriasis (PsO), who are candidates for phototherapy or systemic therapy. active psoriatic arthritis (PsA) . 1.1. Plaque Psoriasis (PsO) STEQEYMA is indicated for the treatment of adults ...

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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.