TheraRadar
Data updated: May 26, 2026

VISTIDE (cidofovir)

Trial Activity: Stable 2 active trials
Infectious Disease Approved 1996-06-26

Development Insights

M.D. Anderson Cancer Center conducting 2 trials (29%)
7 indications explored (Moderate)
adenovirus infections (1 trials)
transplantation infection (1 trials)
cytomegalovirus (cmv) (1 trials)
2
Indications
--
Phase 3 Trials
29
Years on Market

Details

Status
Discontinued
First Approved
1996-06-26
Routes
INTRAVENOUS
Dosage Forms
SOLUTION

Companies

Active Ingredient: CIDOFOVIR

VISTIDE Approval History

1997
1998
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
Original
New Indication
New Form
Label Update
5 FDA actions from 1996 to 2013 · 1 indication expansions
Nov 2013 SUPPL
Mfg · Manufacturing (CMC)
Jun 2001 SUPPL
Mfg · Manufacturing (CMC)
Mar 1999 SUPPL
Efficacy

What VISTIDE Treats

2 FDA approvals

Originally approved for its first indication in 1996 . Covers 2 distinct patient populations.

  • Other (2)
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Clinical Trial Registry

7 trials
Trial Sponsor ID Phase Status Title
NCT07387367 ENOVIA BCV-PA02 Ph 3 recruiting A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT
NCT01295645 2010-0518 NCI-2011-00250 Ph 2 active not recruiting Cidofovir Versus Best Supportive Care for Hemorrhagic Cystitis
NCT02931539 results posted SHP620-303 2015-004725-13 Ph 3 completed Efficacy and Safety Study of Maribavir Treatment Compared to Investigator-assigned Treatment in Transplant Recipients With Cytomegalovirus (CMV) Infections That Are Refractory or Resistant to Treatment With Ganciclovir, Valganciclovir, Foscarnet, or Cidofovir
NCT02567149 Version 1.0 Ph 2 withdrawn Intralesional Cidofovir for the Treatment of Recalcitrant Warts in the Pediatric Immune-suppressed Population.
NCT01816646 2012-0903 NCI-2013-02184 Ph 1 completed Intravesical Cidofovir for Hemorrhagic Cystitis
NCT02976987 CHUB-POST-Colvir II Ph 2 completed A Prolongation of a Clinical Study to Evaluate the Efficacy of an Aqueous Gel Containing 2% (w/w) of Cidofovir, Directly Applied on the Cervix Exhibiting High Grade Squamous Intraepithelial Lesions.
NCT02515877 HPV-RX 2007-005505-21 2007/1297 Ph 1 completed Modulation of the Expression of Papillomavirus (HPV) Oncoproteins to Major the Radiosensitivity: Trial Combining an Antiviral Agent VISTIDE and Radiochemotherapy in Cervical Cancers
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Active Pipeline

Pro

Ongoing clinical trials by development phase

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Key Completed Trials

Pro

Completed studies with published results, ranked by significance

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

VISTIDE FDA Label Details

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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.

How We Calculate These Metrics

Trial Activity Stage

Measures the current development activity pattern based on trial phases, status, and trends. Important: This measures R&D activity, not commercial lifecycle.

Trial statuses: "Active" means recruiting or ongoing. "Completed" means reached planned endpoint. "Terminated" means stopped early—often due to safety, efficacy, or business reasons.

  • Growth: High proportion of early-phase trials (Phase 1/2), active development
  • Expansion: Significant Phase 3 activity, approaching or pursuing approvals
  • Mature: Substantial Phase 4 post-marketing studies
  • Stable: Mixed phase distribution, steady development
  • Declining: Low active trial ratio, reduced R&D investment