TheraRadar
Data updated: May 26, 2026

XYZAL ALLERGY 24HR (levocetirizine dihydrochloride)

Respiratory Approved 2017-01-31
1
Indication
--
Phase 3 Trials
9
Years on Market

Details

Status
Over-the-counter
First Approved
2017-01-31
Patent Cliff
2027

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Routes
ORAL
Dosage Forms
TABLET, SOLUTION

Companies

Active Ingredient: LEVOCETIRIZINE DIHYDROCHLORIDE

XYZAL ALLERGY 24HR Approval History

2018
2019
2020
2021
2022
2023
2024
2025
2026
Original
New Indication
New Form
Label Update
8 FDA actions from 2017 to 2026
Mar 2026 SUPPL
Label · Labeling
Jul 2025 SUPPL
Mfg · Manufacturing (CMC)
Jul 2024 SUPPL
Label · Labeling

What XYZAL ALLERGY 24HR Treats

1 FDA approvals

Originally approved for its first indication in 2017 .

  • Other (1)
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Clinical Trial Registry

4 trials
Trial Sponsor ID Phase Status Title
NCT04699604 HAS3 STUDY00001262 5R01HD100545-05 Ph 3 recruiting A Histamine Pharmacodynamic Biomarker to Guide Treatment in Pediatric Asthma (HAS3)
NCT00621959 results posted A00430 Ph 4 completed A Study Evaluating the Efficacy and Impact on Health-related Quality of Life of Levocetirizine in Adults With Seasonal Allergic Rhinitis
NCT01567501 Ipca/ARL/059 Ph 1 completed Bioequivalence Study of Levocetirizine Dihydrochloride Tablets 5 mg Under Fed Condition
NCT00653224 results posted A00431 Ph 4 completed A Study Evaluating the Efficacy and Impact on Health-related Quality of Life of Levocetirizine in Adults With Seasonal Allergic Rhinitis
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Active Pipeline

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Key Completed Trials

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Completed studies with published results, ranked by significance

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

XYZAL ALLERGY 24HR FDA Label Details

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1 OB patents · 1 families · 39 international docs across 26 countries

XYZAL ALLERGY 24HR Patents & Exclusivity

Latest Patent: Oct 2027

Patents (1 active)

US8633194 Expires Oct 16, 2027
Source: FDA Orange Book

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Revenue Insights

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Patent Timeline

  • Cliff: 2027
  • 1 active patents

Trial Analysis

  • Clinical trial tracking
  • Development stage analysis

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  • Same target/indication analysis
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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.