TheraRadar
Data updated: May 26, 2026

YCANTH (cantharidin)

Trial Activity: Declining
Dermatology Approved 2023-07-21

YCANTH is indicated for the treatment of Molluscum Contagiosum.

Source: FDA Label • VERRICA PHARMS

How YCANTH Works

The mechanism of action of cantharidin in the treatment of molluscum contagiosum is unknown.

Development Insights

GlaxoSmithKline conducting 1 trials (33%)
2 indications explored (Focused)
molluscum contagiosum (2 trials)
arthritis, rheumatoid (1 trials)
1
Indication
--
Phase 3 Trials
2
Years on Market

Details

Status
Prescription
First Approved
2023-07-21
Patent Cliff
2041

Pro Metrics

Patent cliff and revenue data

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Routes
TOPICAL
Dosage Forms
SOLUTION

Companies

Active Ingredient: CANTHARIDIN

YCANTH Approval History

2024
2025
2026
Original
New Indication
New Form
Label Update
1 FDA actions from 2023 to 2023
Jul 2023 ORIGINAL
Update · Type 5 - New Formulation or New Manufacturer

What YCANTH Treats

1 indications

YCANTH is approved for 1 conditions since its original approval in 2023. These indications span multiple therapeutic areas including oncology, immunology, and more.

  • Molluscum Contagiosum
Source: FDA Label

YCANTH Competitive Set

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Three rings of competition based on shared molecular targets and treated indications.

Indication competitors

1

Same indication, different mechanism — what else might this patient receive?

Filters applied: drops same-active-ingredient (505(b)(2) reformulations), route-mismatch (topical vs systemic), and cross-therapeutic-area matches in same-indication rings.

Drugs Similar to YCANTH

FDA-approved drugs for similar conditions. Compare mechanisms and indications to understand treatment alternatives.

ZELSUVMI
BERDAZIMER SODIUM
1 shared
LNHC
Shared indications:
Molluscum Contagiosum
📋

Clinical Trial Registry

3 trials
Trial Sponsor ID Phase Status Title
NCT03306589 results posted 207654 Ph 1 completed Lipopolysaccharide (LPS) or Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Challenge Study on Healthy Subjects
NCT03017846 results posted 16-10-195 Ph 2 completed Safety and Efficacy of Topical Cantharidin for the Treatment of Molluscum Contagiosum, Phase 2
NCT02665260 results posted 12-01-004 Ph 2 completed Safety and Efficacy Study of Topical Cantharidin for the Treatment of Molluscum Contagiosum
🔬

Active Pipeline

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Ongoing clinical trials by development phase

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Key Completed Trials

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Completed studies with published results, ranked by significance

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

YCANTH FDA Label Details

Indications & Usage

FDA Label (PDF)

YCANTH is indicated for the treatment of Molluscum Contagiosum.

View full patent landscape →
4 OB patents · 3 families · 97 international docs across 12 countries

YCANTH Patents & Exclusivity

Latest Patent: Feb 2041
Exclusivity: Jul 2028

Patents (4 active)

US12290651 Expires Feb 19, 2041
US12233042 Expires Aug 22, 2038
US11147790 Expires Aug 22, 2038
US11052064 Expires May 28, 2035

Exclusivity

NCE Until Jul 2028
Source: FDA Orange Book

Pro Intelligence Preview

Deep insights for YCANTH

Revenue Insights

  • Quarterly revenue tracking
  • Historical trend analysis

Patent Timeline

  • Cliff: 2041
  • 6 active patents

Trial Analysis

  • 3 total trials
  • Stage: Declining

Competitive Landscape

  • 1 similar drugs
  • Same target/indication analysis
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Full approval history • All patents • Revenue trends • Competitor analysis

Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.

How We Calculate These Metrics

Trial Activity Stage

Measures the current development activity pattern based on trial phases, status, and trends. Important: This measures R&D activity, not commercial lifecycle.

Trial statuses: "Active" means recruiting or ongoing. "Completed" means reached planned endpoint. "Terminated" means stopped early—often due to safety, efficacy, or business reasons.

  • Growth: High proportion of early-phase trials (Phase 1/2), active development
  • Expansion: Significant Phase 3 activity, approaching or pursuing approvals
  • Mature: Substantial Phase 4 post-marketing studies
  • Stable: Mixed phase distribution, steady development
  • Declining: Low active trial ratio, reduced R&D investment