TheraRadar
Data updated: May 26, 2026

ZAFIRLUKAST

Leukotriene Receptor Antagonists
Respiratory Approved 2010-11-18

ZAFIRLUKAST is indicated for the treatment of Asthma.

Source: FDA Label • Dr. Reddy's
4
Indications
--
Phase 3 Trials
15
Years on Market

Details

Status
Prescription
First Approved
2010-11-18
Routes
ORAL
Dosage Forms
TABLET

ZAFIRLUKAST Approval History

2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
Original
New Indication
New Form
Label Update
12 FDA actions from 2010 to 2023
Nov 2023 ORIGINAL
Update
Aug 2022 ORIGINAL
Update
Sep 2020 ORIGINAL
Update

What ZAFIRLUKAST Treats

1 indications

ZAFIRLUKAST is approved for 1 conditions since its original approval in 2010. These indications span multiple therapeutic areas including oncology, immunology, and more.

  • Asthma
Source: FDA Label

ZAFIRLUKAST Competitive Set

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Filters applied: drops same-active-ingredient (505(b)(2) reformulations), route-mismatch (topical vs systemic), and cross-therapeutic-area matches in same-indication rings.

Drugs Similar to ZAFIRLUKAST

3 of 20

FDA-approved drugs for similar conditions. Compare mechanisms and indications to understand treatment alternatives.

ACCOLATE
ZAFIRLUKAST
1 shared
STRIDES PHARMA INTL
Shared indications:
ADVAIR HFA
FLUTICASONE PROPIONATE
1 shared
GSK
Shared indications:
AIRDUO RESPICLICK
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Teva
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Clinical Trial Registry

3 trials
Trial Sponsor ID Phase Status Title
NCT04339140 results posted 19-814 1R21CA231000-01A1 Ph 2 completed Zafirlukast in Treatment of Marker Relapsed Ovarian Cancer
NCT06069063 ACC001 Ph 2 not yet recruiting Crossover Study of Zafirlukast in Preventing Allergen-induced Signs and Symptoms in Response to Cat Dander Challenge
NCT02950480 results posted 15754 Ph 2 terminated Breast Capsular Contracture Following Post-Mastectomy Reconstruction in Women Treated With the Leukotriene Inhibitor Zafirlukast: A Phase II Trial
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Active Pipeline

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Ongoing clinical trials by development phase

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Key Completed Trials

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Completed studies with published results, ranked by significance

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

ZAFIRLUKAST FDA Label Details

Indications & Usage

ZAFIRLUKAST is indicated for the treatment of Asthma.

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Full clinical data, patents, trials, and competitive landscape for zafirlukast.

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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.