TheraRadar
Data updated: May 26, 2026

ZINGO (lidocaine hydrochloride)

Pain Approved 2007-08-16

Zingo is an amide local anesthetic indicated for use on intact skin to provide local analgesia prior to venipuncture or peripheral intravenous cannulation in children (3–18 years of age) and prior to venipuncture in adults. It is for external use only and must be applied to intact skin.

Source: FDA Label • POWDER PHARMS

How ZINGO Works

Zingo works by delivering lidocaine hydrochloride into the dermis. As an amide-type local anesthetic, lidocaine blocks sodium ion channels required for the initiation and conduction of neuronal impulses, resulting in local anesthesia at the application site.

2
Indications
--
Phase 3 Trials
18
Years on Market

Details

Status
Prescription
First Approved
2007-08-16
Patent Cliff
2035

Pro Metrics

Patent cliff and revenue data

Unlock with Pro
Routes
INTRADERMAL
Dosage Forms
SYSTEM

Companies

Active Ingredient: LIDOCAINE HYDROCHLORIDE

ZINGO Approval History

2008
2009
2010
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
Original
New Indication
New Form
Label Update
6 FDA actions from 2007 to 2025 · 1 indication expansions
Dec 2025 SUPPL
Label · Labeling
Nov 2018 SUPPL
Label · Labeling
Sep 2014 SUPPL
Mfg · Manufacturing (CMC)

What ZINGO Treats

1 indications

ZINGO is approved for 1 conditions since its original approval in 2007. These indications span multiple therapeutic areas including oncology, immunology, and more.

  • Analgesia
Source: FDA Label

ZINGO Competitive Set

Pro

Three rings of competition based on shared molecular targets and treated indications.

Unlock 7 more competitors across all three rings.
Upgrade to Pro

Filters applied: drops same-active-ingredient (505(b)(2) reformulations), route-mismatch (topical vs systemic), and cross-therapeutic-area matches in same-indication rings.

Drugs Similar to ZINGO

3 of 8

FDA-approved drugs for similar conditions. Compare mechanisms and indications to understand treatment alternatives.

BUPIVACAINE HYDROCHLORIDE AND EPINEPHRINE
BUPIVACAINE HYDROCHLORIDE
1 shared
Pfizer
Shared indications:
Analgesia
MARCAINE HYDROCHLORIDE
BUPIVACAINE HYDROCHLORIDE
1 shared
Pfizer
Shared indications:
Analgesia
MARCAINE HYDROCHLORIDE PRESERVATIVE FREE
BUPIVACAINE HYDROCHLORIDE
1 shared
Pfizer
Shared indications:
Analgesia
📋

Clinical Trial Registry

19 trials
Trial Sponsor ID Phase Status Title
NCT07054801 LIMSAH 23-40755 Ph 2 not yet recruiting IA Lidocaine and Methylprednisolone for Headache Associated With Subarachnoid Hemorrhage
NCT03854344 results posted 143321 Ph 4 completed Liposomal Bupivacaine Versus Lidocaine for Skin Graft Donor Site Pain
NCT07205757 R 751 Ph 4 recruiting Adding Lidocaine to Custodiol Mixture
NCT06462781 LIGHT 1 23-267 Ph 1 completed Localized Injection of Lidocaine and Glucocorticoid for Headache Treatment Phase 1
NCT05670236 results posted 32283 Ph 4 completed Effect of Knee Pain on Walking Biomechanics
NCT04524130 610/2563(IRB3) Ph 4 completed Intraoperative Lidocaine and Combined With Ketamine on Opioid After Bariatric Surgery
NCT05201313 LISPRAY 0042698/P/GEN/ARCS Ph 3 completed Efficacy and Safety of the Application of Local Anaesthetic in Spray to Repair of 1st- 2nd Perineal Lacerations
NCT03967197 2020-8355 Ph 2, Ph 3 completed Lidocaine Before Esophageal Manometry and Ambulatory pH Monitoring
NCT03254394 results posted 201705166 Ph 1, Ph 2 completed Lidocaine for Oxaliplatin-induced Neuropathy
NCT03310970 results posted 201701725 Ph 4 completed Pharmacokinetics of Lidocaine in Healthy Adults
NCT03885596 results posted CA-PS-205 Ph 2 completed Open-Label CA-008 (Vocacapsaicin) in Bunionectomy
NCT03667001 COALAS CTU 17/026 Ph 3 completed Comparing Analgesic Efficacy of Systemic Lidocaine Against Placebo in General Anesthesia in Bariatric Surgery
NCT04491474 2020/514/169/20 Ph 4 completed Comparison of Great Occipital Nerve and Supraorbital Nerve Blockade Methods at Treatment of Acute Migraine Attack in the Emergency Department
NCT03484650 2344 Ph 3 withdrawn Systemic Lidocaine Infusion for Pain Control in Ventral Hernia
NCT03787147 VR adult 2018-9613 Ph 2 withdrawn Assessing the Efficacy of Virtual Reality Analgesia (VRA) in Adult Patients for Pain Control During Spinal Injections (SI)
NCT03825016 AS1855 Ph 2 completed Lidocaine Infusion in Hystroscopy
NCT03096444 results posted 20170087 Ph 2 terminated Antipruritic Effect of Topical Ketamine, Amitriptyline, and Lidocaine
NCT02120261 USAMPS results posted HSC-MS-14-0072 Ph 4 terminated Using Saline for Myofascial Pain Syndromes (USAMPS)
NCT02689856 Hydro/Lido 143-6151-201 Ph 2 completed Safety and Efficacy of Hydrocortisone and Lidocaine Treatment of Grade I and II Hemorrhoids
🔬

Active Pipeline

Pro

Ongoing clinical trials by development phase

Loading...

Key Completed Trials

Pro

Completed studies with published results, ranked by significance

Loading...
📊

Trial Timeline

Full development history with FDA approval milestones

|
Loading...
Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

ZINGO FDA Label Details

Indications & Usage

FDA Label (PDF)

ZINGO is indicated for the treatment of Analgesia.

View full patent landscape →
3 OB patents · 2 families · 36 international docs across 11 countries

ZINGO Patents & Exclusivity

Latest Patent: Sep 2035

Patents (3 active)

US9370622 Expires Sep 28, 2035
US9358338 Expires Apr 27, 2035
US8540665 Expires Oct 22, 2029
Source: FDA Orange Book

Pro Intelligence Preview

Deep insights for ZINGO

Revenue Insights

  • Quarterly revenue tracking
  • Historical trend analysis

Patent Timeline

  • Cliff: 2035
  • 3 active patents

Trial Analysis

  • Clinical trial tracking
  • Development stage analysis

Competitive Landscape

  • 8 similar drugs
  • Same target/indication analysis
Unlock Full Intelligence

Full approval history • All patents • Revenue trends • Competitor analysis

Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.