TheraRadar
Data updated: May 26, 2026

ZONTIVITY (vorapaxar sulfate)

Cardiovascular Approved 2014-05-08
Jump to: Indications Approvals Trials Competitors Safety Patents
1
Indication
--
Phase 3 Trials
12
Years on Market

Details

Status
Discontinued
First Approved
2014-05-08
Patent Cliff
2027

Pro Metrics

Patent cliff and revenue data

Unlock with Pro
Routes
ORAL
Dosage Forms
TABLET

Companies

KEY THERAP
Active Ingredient: VORAPAXAR SULFATE

ZONTIVITY Approval History

2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
Original
New Indication
New Form
Label Update
4 FDA actions from 2014 to 2019
Nov 2019 SUPPL
Label · Labeling
FDA Letter Label
Jul 2015 SUPPL
Mfg · Manufacturing (CMC)
Apr 2015 SUPPL
Label · Labeling
FDA Letter Label

What ZONTIVITY Treats

1 FDA approvals

Originally approved for its first indication in 2014 .

  • Other (1)
📋

Clinical Trial Registry

1 trials
Trial Sponsor ID Phase Status Title
NCT02475837 results posted 33763 Ph 2 completed Vorapaxar Study for Maturation of AV Fistulae for Hemodialysis Access
🔬

Active Pipeline

Pro

Ongoing clinical trials by development phase

Loading...
⭐

Key Completed Trials

Pro

Completed studies with published results, ranked by significance

Loading...
📊

Trial Timeline

ClinicalTrials.gov ↗ Pro

Full development history with FDA approval milestones

|
Loading...
Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

ZONTIVITY FDA Label Details

View full patent landscape →
1 OB patents · 1 families · 86 international docs across 34 countries

ZONTIVITY Patents & Exclusivity

Latest Patent: Dec 2027

Patents (1 active)

US7304078 Expires Dec 23, 2027
Source: FDA Orange Book

Pro Intelligence Preview

Deep insights for ZONTIVITY

Revenue Insights

  • • Quarterly revenue tracking
  • • Historical trend analysis

Patent Timeline

  • • Cliff: 2027
  • • 1 active patents

Trial Analysis

  • • Clinical trial tracking
  • • Development stage analysis

Competitive Landscape

  • • Competitor tracking
  • • Same target/indication analysis
Unlock Full Intelligence

Full approval history • All patents • Revenue trends • Competitor analysis

Data Sources

FDA Approval: NDA204886 → Patents: FDA Orange Book → Trials: ClinicalTrials.gov →

Data sourced from official FDA and NIH databases. Click links to verify on original sources.