TheraRadar
Data updated: Jul 17, 2026

ZYRTEC ALLERGY (cetirizine hydrochloride) · KENVUE BRANDS

Respiratory Approved 1995-12-08

ZYRTEC ALLERGY is FDA-approved to treat 2 conditions (same as CETIRIZINE HYDROCHLORIDE).

5
Indications
--
Phase 3 Trials
30
Years on Market

Details

Status
Over-the-counter
First Approved
1995-12-08
Routes
ORAL
Dosage Forms
TABLET, TABLET, ORALLY DISINTEGRATING

Companies

Active Ingredient: CETIRIZINE HYDROCHLORIDE

ZYRTEC ALLERGY Approval History

1996
1997
1998
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
Original
New Indication
New Form
Label Update
78 FDA actions from 1995 to 2026 · 3 indication expansions
Jul 2026 SUPPL
Label · Labeling
Jun 2026 SUPPL
Label · Labeling
Apr 2025 SUPPL
Label · Labeling

What ZYRTEC ALLERGY Treats

2 indications

ZYRTEC ALLERGY is approved for 2 conditions since its original approval in 1995. These indications span multiple therapeutic areas including oncology, immunology, and more.

  • Perennial allergic rhinitis
  • Chronic idiopathic urticaria

Same approved indications as CETIRIZINE HYDROCHLORIDE (same active ingredient).

Source: FDA Label
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Active Pipeline

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Ongoing clinical trials by development phase

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Key Completed Trials

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Completed studies with published results, ranked by significance

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

ZYRTEC ALLERGY FDA Label Details

Indications & Usage

FDA Label (PDF)

ZYRTEC ALLERGY is FDA-approved to treat 2 conditions — same approved indications as CETIRIZINE HYDROCHLORIDE.

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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.