Factor XIa Inhibitors
1 drugs1
Approved Drugs
1
Companies
0
Indications
1
Therapeutic Areas
Factor XIa Drug Modality Landscape
Modalities
Small molecule
1
100%
Routes of Administration
💊 Oral
1
100%
💡
Only one approved drug targets Factor XIa, using small molecule modality.
Oral option available Small molecules only
Factor XIa Clinical Trials 3 trials
Phase 1-4 trials started in 2008 or later that test an FDA-approved drug acting on Factor XIa. Source: ClinicalTrials.gov. How we count
3
Total Trials
0
Active
2
Completed
67%
Completion Rate
Completion by Phase
| Phase | Total | Completed | Stopped | Active | Completion |
|---|---|---|---|---|---|
| Phase 1 | 1 | 1 | 0 | 0 | 100% |
| Phase 3 | 2 | 1 | 1 | 0 | 50% |
Top Sponsors
Bayer 3 67%
By Modality
Small molecule 3 67%
Top Conditions
Atrial Fibrillation 2 50%
Prevention of Ischemic ... 1 100%
Acute Non-cardioembolic... 1 100%
High-risk Transient Isc... 1 100%
Prevention of Stroke or... 1 0%
Prevention of Thromboem... 1 100%
Acute Myocardial Infarc... 1 100%
Non-cardioembolic Ische... 1 100%
Hepatic Impairment 1 100%
Top Drugs
Source: ClinicalTrials.gov · Completion rate = completed ÷ (completed + terminated + withdrawn)
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Clinical Trials Analysis
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How We Count Trials
- Trials: phase 1-4 interventional trials on ClinicalTrials.gov that started in 2008 or later and test an FDA-approved drug acting on Factor XIa. A trial counts if an approved drug acting on Factor XIa is in any arm, including as a comparator, and a trial that tests two such drugs counts once. Trials that test only unapproved drugs are not counted. A trial listed as phase 1/2 counts as phase 1, and phase 2/3 as phase 2.
- Active: recruiting, not yet recruiting, enrolling by invitation, or active and no longer recruiting.
- Completion rate: of the trials that have ended, the share marked Completed rather than Terminated or Withdrawn. Completed means the trial ended as planned; it does not mean the drug worked. Suspended trials are not counted as ended.
- Stopped: terminated or withdrawn. Trials stop for many reasons, including slow enrolment and business decisions, not only safety or efficacy.
- Sponsors: the lead sponsor of each trial. Companies are the sponsors ClinicalTrials.gov classes as industry; the rest are universities, hospitals, cooperative groups, government bodies and individuals.