NCT07583771 NOT YET RECRUITING A Phase Ⅰ Study of CS08399 in Participants With MTAP-deleted Solid Tumors and Lymphoma
Chipscreen Biosciences, Ltd.
NCT07583316 NOT YET RECRUITING A Phase 1 First-in-Human Study of CRPA1A2, a MAGE-A1/HLA-A*02:01 Bispecific T-Cell Engager, in Patients With Solid Tumors
Corregene Biotechnology Co., Ltd
NCT07583914 NOT YET RECRUITING Safety, Tolerability, and Preliminary Antitumor Activity of Non-Cationic Peptide-CD47 siRNA in Advanced Solid Tumors
West China Hospital
NCT05172245 RECRUITING Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer
National Cancer Institute (NCI)
NCT06874335 RECRUITING A Phase 1 Study of BHV-1530 in Advanced Solid Tumors
Biohaven Therapeutics Ltd.
NCT06549751 NOT YET RECRUITING MT-601 Administered To Patients With Locally Advanced Unresectable or Metastatic Pancreatic Cancer
Marker Therapeutics, Inc.
NCT06673329 RECRUITING Brodalumab in the Treatment of Immune-Related Adverse Events
Brian Henick, MD
NCT07156227 NOT YET RECRUITING Testing the Addition of an Anti-Cancer Drug, Camonsertib, to Radiation Therapy for Recurrent Head and Neck Squamous Cell Carcinoma
National Cancer Institute (NCI)
NCT07244835 RECRUITING A Study of DEG6498 in Participants With Solid Tumors
Degron Therapeutics Co.
NCT07583160 ENROLLING BY INVITATION YS247 (Neoantigen-Pulsed DC Vaccine) for Metastatic Prostate Cancer
Changhai Hospital
NCT02496208 ACTIVE NOT RECRUITING Cabozantinib S-malate and Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Genitourinary Tumors
National Cancer Institute (NCI)
NCT06982222 NOT YET RECRUITING Testing the Safety of the Anti-cancer Drug, Sn-117m-DTPA, for Advanced Cancers That Have Spread to Bones
National Cancer Institute (NCI)
NCT07584668 ACTIVE NOT RECRUITING Safety, Tolerability and Pharmacokinetics of EM-I-2024
National Medical Research Radiological Centre of the Ministry of Health of Russia
NCT06904066 RECRUITING Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies
National Cancer Institute (NCI)
NCT07582822 NOT YET RECRUITING JH021 in Patients With Advanced Solid Tumors or EGFR-Mutant NSCLC
Biotech Pharmaceutical Co., Ltd.
NCT07583654 NOT YET RECRUITING Safety, Tolerability, and Preliminary Antitumor Activity of Cationic Peptide-IL22BP mRNA in Advanced Solid Tumors
West China Hospital
NCT07584226 RECRUITING A First-in-human Study of RLY-8161 in Advanced NRAS-Mutant Solid Tumors
Relay Therapeutics, Inc.
NCT04963153 ACTIVE NOT RECRUITING Testing Combination Erdafitinib and Enfortumab Vedotin in Metastatic Bladder Cancer After Treatment With Chemotherapy and Immunotherapy
National Cancer Institute (NCI)
NCT05877599 RECRUITING A Study of NT-175 in Adult Subjects With Unresectable, Advanced, and/or Metastatic Solid Tumors That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation
AstraZeneca
NCT07509034 NOT YET RECRUITING Autologous B7-H3 Chimeric Antigen Receptor T Cells in Previously Treated Extensive-Stage Small Cell Lung Cancer With Recurrent or Refractory Disease
National Cancer Institute (NCI)
NCT04704661 ACTIVE NOT RECRUITING Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial
National Cancer Institute (NCI)
NCT07584499 RECRUITING Phase I Study of Becotatug Vedotin for Safety and Efficacy in EGFR-Positive Pediatric Relapsed/Refractory or Metastatic Solid Tumors
Sun Yat-sen University
NCT07419841 RECRUITING A Phase 1 Study of the Safety and Tolerability of CTX-10726
Compass Therapeutics
NCT02298959 ACTIVE NOT RECRUITING Testing the PD-1 Antibody, MK3475, Given With Ziv-aflibercept in Patients With Advanced Cancer
National Cancer Institute (NCI)
NCT07584954 RECRUITING Phase I, Open-labeled, Dose-escalation, Dose-expansion Study Evaluating the Safety, Tolerance, Pharmacokinetics, and Activity of IUAb190708 in Patients With Advanced or Recurrent Solid Tumors
Jun Zhou
NCT04855435 RECRUITING Safety and Preliminary Efficacy of MBS8(1V270) in Cancer Patients With Advanced Solid Tumours
MonTa Biosciences ApS
NCT06465069 RECRUITING A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
Eli Lilly and Company
NCT06150157 RECRUITING A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms
Janssen Research & Development, LLC
NCT06659341 RECRUITING A Phase I Study of BAY3498264 Given Together With Sotorasib in Participants Who Have Advanced Solid Cancers With Specific Genetic Changes Called KRASG12C Mutation
Bayer
NCT05614739 RECRUITING FORAGER-1: A Study of LOXO-435 (LY3866288) in Participants With Cancer With a Change in a Gene Called FGFR3
Eli Lilly and Company
NCT05906537 ACTIVE NOT RECRUITING SKB410 for Injection in Solid Tumors
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.
NCT06589596 RECRUITING An Investigational Study of BGB-58067 As a Single Agent and in Combination With Anticancer Agents in Participants With Advanced Solid Tumors
BeOne Medicines
NCT06132113 RECRUITING DAREON™-7: A Study to Test How Well Different Doses of BI 764532 in Addition to Chemotherapy Are Tolerated by People With Advanced Neuroendocrine Cancers
Boehringer Ingelheim
NCT07458347 RECRUITING A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation
Kestrel Therapeutics, Inc.
NCT06747390 RECRUITING Intratumoral Lidocaine Injection Before Oropharyngeal Cancer Surgery
Ryan Carey
NCT05647122 RECRUITING First in Human Study of AZD9592 in Solid Tumors
AstraZeneca
NCT06596473 RECRUITING A Study of BG-C477 in Participants With Advanced Solid Tumors
BeOne Medicines
NCT07578571 NOT YET RECRUITING A Phase 1 Study of IM-1617 in Participants With Advanced Cancer
Immunome, Inc.
NCT04337177 ACTIVE NOT RECRUITING Flavored, Oral Irinotecan VAL-413 (Orotecan®) Given With Temozolomide for Treatment of Recurrent Pediatric Solid Tumors
Valent Technologies, LLC
NCT07222267 RECRUITING An Investigational Study of BG-75202 Alone and in Combination With Other Therapeutic Agents in Adults With Advanced Solid Tumors
BeOne Medicines
NCT07560943 RECRUITING Safety and Tolerability of AI-Designed Pan-Cancer Neoantigen mRNA Vaccine (PAN-NeoVax) in Advanced Solid Tumors
West China Hospital
NCT04502602 ACTIVE NOT RECRUITING Niraparib and Neratinib in Advanced Solid Tumors With Expansion Cohort in Advanced Ovarian Cancer
Virginia Commonwealth University
NCT06625593 RECRUITING A First-in-Human (FIH) Study of BG-C137, an Anti-Fibroblast Growth Factor Receptor 2b (FGFR2b) Antibody Drug Conjugate, in Participants With Advanced Solid Tumors
BeOne Medicines
NCT07128680 RECRUITING Immunotherapy (Nivolumab and Ipilimumab) With and Without a Live Biotherapeutic Product (EXL01) for the Treatment of Metastatic Renal Cell Cancer
City of Hope Medical Center
NCT07562815 NOT YET RECRUITING Safety and Tolerability of NCP-IL-22BP mRNA in Advanced Solid Tumors
West China Hospital
NCT05581004 RECRUITING A Study to Evaluate the Safety, Pharmacokinetics, and Activity of Enzelkitug as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors
Genentech, Inc.
NCT07247110 RECRUITING A Clinical Study of MK-4716 in People With Certain Solid Tumors (MK-4716-001)
Merck Sharp & Dohme LLC
NCT07414836 RECRUITING A First-in-Human Study of BG-C0979 in Adults With Advanced Solid Tumors
BeOne Medicines
NCT07563972 RECRUITING Intratumoral Macrophage Exosomes With Mechanobiological Reprogramming for Advanced Solid Tumors
West China Hospital
NCT07226349 RECRUITING A Study of BG-75098 Alone and in Combination With Other Agents in Adults With Advanced Solid Tumors
BeOne Medicines
NCT07524348 RECRUITING A Trial to Investigate the Safety of E303 in Participants With Advanced Refractory Solid Tumors
Samsung Bioepis Co., Ltd.
NCT04389632 RECRUITING A Study of Sigvotatug Vedotin in Advanced Solid Tumors
Seagen, a wholly owned subsidiary of Pfizer
NCT06257264 RECRUITING A Study to Examine the Safety of Different Doses of BG-68501 Given to Participants With Advanced-Stage Tumors
BeiGene
NCT05538130 RECRUITING A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors
Pfizer
NCT07181681 RECRUITING A First-in-Human Study of BG-C0902 Alone and in Combination With Other Therapeutic Agents in Patients With Advanced Solid Tumors
BeOne Medicines
NCT06826040 RECRUITING SKB445 for Injection in Solid Tumors
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.
NCT07082920 RECRUITING A Study of JNJ-78278343 in Combination With JNJ-95298177 for Treatment of Prostate Cancer
Janssen Research & Development, LLC
NCT04898634 ACTIVE NOT RECRUITING A Study of JNJ-78278343, a T-Cell-Redirecting Agent Targeting Human Kallikrein 2 (KLK2), for Advanced Prostate Cancer
Janssen Research & Development, LLC
NCT06004245 RECRUITING A Study to Evaluate the Safety, Pharmacokinetics, and Anti-Tumor Activity of VVD-133214 as Monotherapy and in Combination in Participants With Advanced Solid Tumors
Vividion Therapeutics, Inc.
NCT07087197 RECRUITING A Study of SKB107 in Advanced Solid Tumors With Bone Metastases
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.
NCT05954312 RECRUITING A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-130037 in Participants With Advanced Solid Tumors
Vividion Therapeutics, Inc.
NCT06651229 RECRUITING A Study of JNJ-90189892 for Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Neoplasms
Janssen Research & Development, LLC
NCT06253520 ACTIVE NOT RECRUITING Autologous T-cells Genetically Engineered to Express Receptors Reactive Against KRAS Mutations in Conjunction With a Vaccine Directed Against These Antigens in Participants With Metastatic Cancer
National Cancer Institute (NCI)
NCT06663319 RECRUITING A Study of JNJ-89402638 for Metastatic Colorectal and Gastric Cancers
Janssen Research & Development, LLC
NCT05567185 ACTIVE NOT RECRUITING A Study of Erdafitinib Intravesical Delivery System in Japanese Participants With Bladder Cancer
Janssen Pharmaceutical K.K.
NCT02123758 ACTIVE NOT RECRUITING A Study of JNJ-56021927 (ARN-509) and Abiraterone Acetate in Participants With Metastatic Castration-Resistant Prostate Cancer
Aragon Pharmaceuticals, Inc.
NCT07371104 RECRUITING Bioequivalence Study of DWZ2501 in Patients With Advanced BRCA-mutated High-grade Ovarian Cancer
Daewoong Pharmaceutical Co. LTD.
NCT02592317 ACTIVE NOT RECRUITING A Study to Evaluate the Effect of Multiple Doses of JNJ-56021927 on the Pharmacokinetics of Multiple Cytochrome P450 and Transporter Substrates in Participants With Castration-Resistant Prostate Cancer
Aragon Pharmaceuticals, Inc.
NCT06251310 RECRUITING SW-682 in Advanced Solid Tumors
SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, Germany
NCT05963867 RECRUITING A Study to Test How BI 764532 is Taken up by Tumours in People With Small-cell Lung Cancer or Neuroendocrine Cancer
Boehringer Ingelheim
NCT06641908 RECRUITING Anti-GD2 ADC M3554 in Advanced Solid Tumors
EMD Serono Research & Development Institute, Inc.
NCT06428331 RECRUITING A Study of SKB518 in Patients With Advanced Solid Tumors
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.
NCT07107230 RECRUITING A Study of JNJ-95437446 in Participants With Advanced-Stage Solid Tumors
Janssen Research & Development, LLC
NCT04644770 ACTIVE NOT RECRUITING A Study of JNJ-69086420, an Actinium-225-Labeled Antibody Targeting Human Kallikrein-2 (hK2) for Advanced Prostate Cancer
Janssen Research & Development, LLC
NCT03523442 ACTIVE NOT RECRUITING A Study of Androgen Receptor (AR) Antagonist Apalutamide in Chinese Participants With Metastatic Castration-Resistant Prostate Cancer
Janssen Research & Development, LLC
NCT05818683 RECRUITING A Study of Pasritamig (JNJ-78278343) in Combination With Other Agents for Metastatic Prostate Cancer
Janssen Research & Development, LLC
NCT05872295 RECRUITING IKS014 in Advanced Solid Tumors That Express HER2
Iksuda Therapeutics Ltd.
NCT05367635 RECRUITING A Study of SKB315 in Patients With Advanced Solid Tumors
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.
NCT00777582 ACTIVE NOT RECRUITING Phase I Comparative Bioavailability Study
AstraZeneca
NCT06788509 ENROLLING BY INVITATION A Rollover Study for Continued Study Treatment and Ongoing Safety Monitoring
Janssen Research & Development, LLC
NCT06178614 RECRUITING A Study of JNJ-87890387 for Advanced Solid Tumors
Janssen Research & Development, LLC
NCT07223125 RECRUITING A Study of JNJ-89862175 for Treatment of Advanced Solid Tumors
Janssen Research & Development, LLC
NCT06311578 RECRUITING A Study of JNJ-87704916, as Monotherapy and in Combination for Advanced Solid Tumors
Johnson & Johnson Enterprise Innovation Inc.
NCT07161414 RECRUITING A Study to Investigate the Pharmacokinetics and Safety of Subcutaneous Rilvegostomig in Adult Participants With Advanced Solid Tumors Previously Treated With Standard of Care Therapy
AstraZeneca
NCT04606381 ACTIVE NOT RECRUITING A Study of Amivantamab Subcutaneous (SC) Administration for the Treatment of Advanced Solid Malignancies
Janssen Research & Development, LLC
NCT06014502 RECRUITING Study to Evaluate IMGS-001 Treatment in Patients With Relapsed or Refractory Advanced Solid Tumors
ImmunoGenesis
NCT06618001 ACTIVE NOT RECRUITING A Study of JNJ-89853413 for Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Neoplasms
Janssen Research & Development, LLC
NCT06736327 RECRUITING A Study on the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of SKB500 in Subjects With Advanced Solid Tumors
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.
NCT04577833 ACTIVE NOT RECRUITING A Study of Comparative Formulations of Niraparib and Abiraterone Acetate (AA) in Men With Prostate Cancer
Janssen Research & Development, LLC
NCT07319871 RECRUITING A Study of Pasritamig (JNJ-78278343) in Combination With JNJ-86974680 for Treatment of Prostate Cancer
Janssen Research & Development, LLC
NCT05981703 RECRUITING A Study Investigating BGB-26808 Alone or in Combination With Tislelizumab in Participants With Advanced Solid Tumors
BeOne Medicines
NCT07462377 RECRUITING A Phase 1 Study of EPI-326 in EGFR-mutant NSCLC and HNSCC
EpiBiologics
NCT05599984 ACTIVE NOT RECRUITING Study to Evaluate Adverse Events, Change in Disease Activity, and How ABBV-706 Moves Through the Body When Intravenously (IV) Infused Alone or in Combination With IV Infused Budigalimab, Cisplatin, or Carboplatin in Adult Participants With Advanced Solid Tumors
AbbVie
NCT04170153 ACTIVE NOT RECRUITING Tuvusertib (M1774) in Participants With Metastatic or Locally Advanced Unresectable Solid Tumors (DDRiver Solid Tumors 301)
EMD Serono Research & Development Institute, Inc.
NCT06555744 ACTIVE NOT RECRUITING A Study of ZW191 in Participants With Solid Tumors
Zymeworks BC Inc.
NCT06726369 RECRUITING A Phase 1 Study to Evaluate the Safety, Pharmacokinetics, and Preliminary Efficacy of MK-6204 (SKB535) for Injection in Participants With Advanced Solid Tumors
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.
NCT07572006 NOT YET RECRUITING A Study of JNJ-95804306 for Relapsed or Refractory Hematological Malignancies
Janssen Research & Development, LLC
NCT07300150 RECRUITING A Study of PT0511 in Participants With KRAS Mutated or Amplified Advanced Solid Tumors
PAQ Therapeutics, Inc.
NCT06835569 RECRUITING A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations
Alterome Therapeutics, Inc.
NCT05220046 ACTIVE NOT RECRUITING Palliadelic Treatment to Reduce Psychological Distress in Persons With Advanced Gastrointestinal Cancers
University of Nebraska
NCT03560882 ACTIVE NOT RECRUITING A Pilot Trial of Atorvastatin in Tumor Protein 53 (p53) -Mutant and p53 Wild-Type Malignancies
Joaquina Baranda
NCT07403721 RECRUITING AMG 436 as Monotherapy and Combination Therapy in Participants With MSI-H/dMMR Solid Tumors
Amgen
NCT07197671 RECRUITING Y-NM600 in Patients Receiving Anti-PD-1 or Anti-PD-L1 for Metastatic Cancer
University of Wisconsin, Madison
NCT07566247 NOT YET RECRUITING A Phase I Clinical Study of AK150 in Advanced Malignant Solid Tumor
Akeso
NCT07387068 RECRUITING Trial to Evaluate the Safety and Preliminary Efficacy of GEN1079 in Participants With Advanced Solid Tumors
Genmab
NCT04620603 ACTIVE NOT RECRUITING Low-Dose-Rate Brachytherapy Combined With Immune Checkpoint Inhibition in Cancer
Case Comprehensive Cancer Center
NCT07416123 RECRUITING A Study of GEN1106 in Participants With Solid Tumors
Genmab
NCT05835687 RECRUITING Loc3CAR: Locoregional Delivery of B7-H3-CAR T Cells for Pediatric Patients With Primary CNS Tumors
St. Jude Children's Research Hospital
NCT06057038 ACTIVE NOT RECRUITING A Safety Trial of GEN1042 in Japanese Subjects With Malignant Solid Tumors
Genmab
NCT06313593 RECRUITING A Study to Evaluate the Safety, Tolerability of INCB160058 in Participants With Myeloproliferative Neoplasms
Incyte Corporation
NCT07195916 RECRUITING A Study to Evaluate INCA036873 in Participants With Advanced Solid Tumors and Hematological Malignancies
Incyte Corporation
NCT06095089 RECRUITING A Study of JNJ-87189401 Combined With JNJ-78278343 for Advanced Prostate Cancer
Janssen Research & Development, LLC
NCT07218003 ENROLLING BY INVITATION A Phase 1/1b of RNDO-564 Single Agent or in Combination With Pembrolizumab in Bladder Cancer and Other Solid Tumors Associated With Nectin-4
Rondo Therapeutics
NCT06031441 RECRUITING A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7566802 as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors
Genentech, Inc.
NCT07563829 NOT YET RECRUITING NPX372, a B7-H7:CD3 Bispecific Antibody, in Selected Solid Tumor Malignancies
NextPoint Therapeutics, Inc.
NCT05067283 RECRUITING A Study of Calderasib (MK-1084) in KRAS Mutant Advanced Solid Tumors (MK-1084-001)
Merck Sharp & Dohme LLC
NCT06480552 RECRUITING An Open-label Dose Escalation/Expansion Trial to Evaluate the Safety and Anti-tumor Activity of TEV-56278 Alone or in Combination With Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors
Teva Branded Pharmaceutical Products R&D LLC
NCT06132503 RECRUITING Safety, Pharmacokinetics, and Clinical Activity of LP-284 in Adult Patients With Relapsed or Refractory Lymphomas and Solid Tumors
Lantern Pharma Inc.
NCT05489237 RECRUITING First-in-human Study of IDRX-42 in Participants With Metastatic and/or Unresectable Gastrointestinal Stromal Tumors
IDRX, Inc., a wholly owned subsidiary of GSK, LLC
NCT05458219 RECRUITING A First-in-human Study of IBI343 in Subjects With Locally Advanced Unresectable or Metastatic Solid Tumors
Innovent Biologics (Suzhou) Co. Ltd.
NCT06619587 RECRUITING A Study to Evaluate Safety, Pharmacokinetics, and Activity of GDC-7035 as a Single Agent and in Combination in Patients With Advanced Solid Tumors
Genentech, Inc.
NCT06179160 RECRUITING A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation
Incyte Corporation
NCT04250545 ACTIVE NOT RECRUITING Testing of the Anti Cancer Drugs CB-839 HCl (Telaglenastat) and MLN0128 (Sapanisertib) in Advanced Stage Non-small Cell Lung Cancer
National Cancer Institute (NCI)
NCT07561554 RECRUITING Phase I Study of HSK42360-Na in Solid Tumors With BRAF V600 Mutation
Haisco Pharmaceutical Group Co., Ltd.
NCT05536141 RECRUITING A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid Tumors
Arcus Biosciences, Inc.
NCT07334119 RECRUITING Safety, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of MT-304 in Adults With Advanced HER2-Expressing Solid Tumors
Myeloid Therapeutics
NCT06349837 RECRUITING Safety and Tolerability of LDRT Plus Concurrent Partial SBRT and Tislelizumab in Patients With Bulky Tumors
Sichuan University
NCT05308732 ACTIVE NOT RECRUITING Safety and Tolerability of the Use of Copaiba in Patients With Oral Cancer Submitted to Radiotherapy
Instituto Nacional de Cancer, Brazil
NCT07469891 RECRUITING A Phase 1 Study of PRT12396 in Participants With Select Myeloproliferative Neoplasms
Prelude Therapeutics
NCT06218914 RECRUITING Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors
AstraZeneca
NCT03366116 RECRUITING 5-aza-4'-Thio-2'-Deoxycytidine (Aza-TdC) in People With Advanced Solid Tumors
National Cancer Institute (NCI)
NCT06120075 ACTIVE NOT RECRUITING A Study of AB801 Monotherapy and Combination Therapy in Participants With Advanced Malignancies
Arcus Biosciences, Inc.
NCT06441331 RECRUITING Phase I Trial to Determine the Dose and Evaluate the PK and Safety of Lutetium Lu 177 Edotreotide Therapy in Pediatric Participants With SSTR-positive Tumors
ITM Solucin GmbH
NCT07558200 NOT YET RECRUITING Phase Ia/Ib Study of FXB0871 Monotherapy in Locally Advanced/Metastatic Solid Tumors
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.
NCT02626312 ACTIVE NOT RECRUITING Radiation Therapy in Treating Patients With Hepatocellular Carcinoma, Cholangiocarcinoma, or Liver Metastasis Who Have Impaired Liver Function
M.D. Anderson Cancer Center
NCT04597411 ACTIVE NOT RECRUITING Study of 225Ac-PSMA-617 in Men With PSMA-positive Prostate Cancer
Endocyte
NCT05359445 ACTIVE NOT RECRUITING IMA401 TCER® in Recurrent and/or Refractory Solid Tumors, Alone or in Combination With a Checkpoint Inhibitor
Immatics Biotechnologies GmbH
NCT07021066 RECRUITING Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of BL-M05D1 in Subjects With Solid Tumors
SystImmune Inc.
NCT04084067 RECRUITING Indocyanine Green (ICG) Guided Tumor Resection
St. Jude Children's Research Hospital
NCT06648434 RECRUITING MK2 Inhibitor in Combination With mFOLFIRINOX for Untreated Metastatic Pancreatic Ductal Adenocarcinoma
Washington University School of Medicine
NCT02993146 ACTIVE NOT RECRUITING Ropidoxuridine and Whole Brain Radiation Therapy in Treating Patients With Brain Metastases
National Cancer Institute (NCI)
NCT05378425 ACTIVE NOT RECRUITING A Study of NTX-1088, a Monoclonal Antibody Targeting the Poliovirus Receptor (PVR, CD155), as Monotherapy and Combined With Pembrolizumab
Nectin Therapeutics Ltd
NCT02589522 ACTIVE NOT RECRUITING Testing the Safety of M6620 (VX-970) When Given With Standard Whole Brain Radiation Therapy for the Treatment of Brain Metastases From Non-small Cell Lung Cancer, Small Cell Lung Cancer, or Neuroendocrine Tumors
National Cancer Institute (NCI)
NCT02495896 ACTIVE NOT RECRUITING Recombinant EphB4-HSA Fusion Protein With Standard Chemotherapy Regimens in Treating Patients With Advanced or Metastatic Solid Tumors
University of Southern California
NCT04460937 ACTIVE NOT RECRUITING Testing the Addition of an Anti-cancer Drug, Adavosertib, to Radiation Therapy for Patients With Incurable Esophageal and Gastroesophageal Junction Cancers
National Cancer Institute (NCI)
NCT02142803 ACTIVE NOT RECRUITING TORC1/2 Inhibitor MLN0128 and Bevacizumab in Treating Patients With Recurrent Glioblastoma or Advanced Solid Tumors
National Cancer Institute (NCI)
NCT02595879 ACTIVE NOT RECRUITING Triapine With Chemotherapy and Radiation Therapy in Treating Patients With IB2-IVA Cervical or Vaginal Cancer
National Cancer Institute (NCI)
NCT06074497 ACTIVE NOT RECRUITING This is an Open Label, Two-part, Multicenter, Phase I Trial to Investigate the Safety, Tolerability, and PK of KGX101 Monotherapy and Combination Therapy With Envafolimab in Patients With Advanced or Metastatic Solid Tumors.
Kangabio AUSTRALIA LTD PTY
NCT07413328 RECRUITING HWS116 Monotherapy in Patients With Advanced Solid Tumors
Wuhan Humanwell Innovative Drug Research and Development Center Limited Company
NCT04958239 ACTIVE NOT RECRUITING A Study to Test BI 765179 Alone and in Combination With Ezabenlimab in Patients With Advanced Cancer (Solid Tumors) and BI 765179 in Combination With Pembrolizumab in Patients With Advanced Head and Neck Cancer
Boehringer Ingelheim
NCT05109975 ACTIVE NOT RECRUITING A Study to Evaluate Safety and Preliminary Anti-tumor Activity of Debio 0123 as Monotherapy in Adult Participants With Advanced Solid Tumors
Debiopharm International SA
NCT07162038 RECRUITING Phase I Trial Integrating HLA-Haploidentical Anti-CD19 CAR-T Cells With Post-Transplantation Cyclophosphamide-Based HLA-Haploidentical Hematopoietic Cell Transplantation
National Cancer Institute (NCI)
NCT07553793 NOT YET RECRUITING Chimeric Antigen Receptor Macrophages Targeting c-MET for Advanced Stage of Pancreatic Cancer Patients
Peking Union Medical College Hospital
NCT04890613 RECRUITING Study of CX-5461 in Patients With Solid Tumours and BRCA1/2, PALB2 or Homologous Recombination Deficiency (HRD) Mutation
Senhwa Biosciences, Inc.
NCT05687682 RECRUITING Safety of AM-928 Infusion in Advanced Solid Tumors
AcadeMab Biomedical Inc.
NCT06147037 RECRUITING A Phase 1, Dose-escalation Study of [225Ac]-FPI-2068 in Adult Patients With Advanced Solid Tumours
AstraZeneca
NCT05879978 ACTIVE NOT RECRUITING A Study to Test How Well Different Doses of Obrixtamig (BI 764532) in Combination With Ezabenlimab Are Tolerated by People With Small Cell Lung Cancer and Other Neuroendocrine Tumours That Are Positive for DLL3
Boehringer Ingelheim
NCT04483778 ACTIVE NOT RECRUITING B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults
Seattle Children's Hospital
NCT06227377 RECRUITING QTX3034 in Patients With KRAS G12D Mutation
Quanta Therapeutics
NCT06389123 RECRUITING Molecularly Targeted Theranostic Approach for the Detection and Treatment of Metastatic Carcinomas
University of California, Davis
NCT07552376 NOT YET RECRUITING This Study Aims to Evaluate the Efficacy and Safety of QLS1317 in Patients With MSI-H/dMMR Advanced Solid Tumors.
Shanghai Qilu Pharmaceutical Research and Development Center LTD
NCT06723236 RECRUITING A Study of MGC028 in Participants With Advanced Solid Tumors
MacroGenics
NCT05187182 RECRUITING CA-4948 in Combination With FOLFOX/PD-1 Inhibitor +/- Trastuzumab for Untreated Unresectable Gastric and Esophageal Cancer
Washington University School of Medicine
NCT04913285 ACTIVE NOT RECRUITING A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors
Pierre Fabre Medicament
NCT07469982 RECRUITING A Phase I Study of SY-9453 in Patients With Advanced Solid Tumors
Shouyao Holdings (Beijing) Co. LTD
NCT07166601 RECRUITING M0324 as Monotherapy and in Combination With Pembrolizumab or Chemotherapy in Participants With Selected Advanced Solid Tumors
EMD Serono Research & Development Institute, Inc.
NCT06132828 RECRUITING Evaluate the Safety, Tolerability, Pharmacokinetics of DR30206 in Patients With Advanced or Metastatic Solid Tumors
Zhejiang Doer Biologics Co., Ltd.
NCT05276310 RECRUITING A Study of IMC-002 in Patients With Advanced Cancer Failed to Standard Therapy
ImmuneOncia Therapeutics Inc.
NCT07177937 RECRUITING A Study of DXC014 in Patients With Advanced Solid Tumors.
Hangzhou DAC Biotechnology Co., Ltd.
NCT07075185 RECRUITING A Study to Evaluate a Novel Gene Therapy in Patients With Relapsed and Refractory Multiple Myeloma
Kelonia Therapeutics, Inc.
NCT07260305 RECRUITING A Phase I Study to Investigate the Safety and Tolerability of KGX101 Monotherapy and Combination Therapy With Envafolimab in Advanced or Metastatic Solid Tumor Patients
Kangabio AUSTRALIA LTD PTY
NCT06816992 RECRUITING ORIC-114 in Combination With Subcutaneous Amivantamab in Patients With EGFR Exon20 Insertion Mutant NSCLC
ORIC Pharmaceuticals
NCT04388852 ACTIVE NOT RECRUITING DS3201 and Ipilimumab for the Treatment of Metastatic Prostate, Urothelial and Renal Cell Cancers
M.D. Anderson Cancer Center
NCT04235777 RECRUITING Bintrafusp Alfa (M7824) and PDS01ADC Alone and in Combination With Stereotactic Body Radiation Therapy (SBRT) in Adults With Metastatic Non-Prostate Genitourinary Malignancies
National Cancer Institute (NCI)
NCT06801002 RECRUITING Trial to Evaluate the Safety & Tolerability of JBZ-001 in Pts With Advanced Solid and Hematological Malignancies
Jabez Bioscience, Inc
NCT06926283 RECRUITING A Study of DXC008 in Patients With Prostate Cancer and Other Solid Tumors
Hangzhou DAC Biotechnology Co., Ltd.
NCT05782361 ACTIVE NOT RECRUITING POTENT - Tepotinib in Combination With Pembrolizumab in NSCLC
Institute of Cancer Research, United Kingdom
NCT05349890 ACTIVE NOT RECRUITING Personalized TCR-T: Study of Adoptively Transferred T-cell Receptor Gene-engineered T Cells (TCR-T)
Providence Health & Services
NCT04222413 RECRUITING Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors
National Cancer Institute (NCI)
NCT05557045 RECRUITING A Study of JZP815 Oral Capsules in Adult Participants With Advanced or Metastatic Solid Tumors Harboring Mitogen Activated Protein Kinase (MAPK) Pathway Alterations to Investigate the Safety, Dosing, and Antitumor Activity of JZP815
Jazz Pharmaceuticals
NCT06720987 RECRUITING A Study to Investigate the Safety and Efficacy of KQB365 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies
Kumquat Biosciences Inc.
NCT06297525 RECRUITING Study of STP938 in Advanced Solid Tumours
Step Pharma, SAS
NCT06260514 RECRUITING Study of APR-1051 in Patients With Advanced Solid Tumors
Aprea Therapeutics
NCT06806046 ACTIVE NOT RECRUITING Anti-CEACAM5 ADC Precemtabart Tocentecan (M9140) in Chinese Participants With Solid Tumors
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
NCT03696030 ACTIVE NOT RECRUITING HER2-CAR T Cells in Treating Patients With Recurrent Brain or Leptomeningeal Metastases
City of Hope Medical Center
NCT07541573 RECRUITING GTB-5550 in Advanced Solid Tumors
Masonic Cancer Center, University of Minnesota
NCT06607185 ACTIVE NOT RECRUITING A Study of the Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid Tumors
Eli Lilly and Company
NCT06840886 RECRUITING A Study of PHST001 in Advanced Solid Tumors
Pheast Therapeutics
NCT04521686 ACTIVE NOT RECRUITING Study of LY3410738 Administered to Patients With Advanced Solid Tumors With IDH1 or IDH2 Mutations
Eli Lilly and Company
NCT07545356 NOT YET RECRUITING A Study of KIVU-305 in Participants With Locally Advanced or Metastatic Solid Tumors
Kivu Bioscience Inc.
NCT06347068 RECRUITING Study of Autologous CAR-T Cells Targeting B7-H3 in TNBC iC9-CAR.B7-H3 T Cells
UNC Lineberger Comprehensive Cancer Center
NCT07204340 RECRUITING TLN-372 in Advanced KRAS Mutant Solid Tumors
Treeline Biosciences, Inc.
NCT02204098 ACTIVE NOT RECRUITING Safety and Immune Response to a Mammaglobin-A DNA Vaccine In Breast Cancer Patients Undergoing Neoadjuvant Endocrine Therapy
Washington University School of Medicine
NCT07346846 RECRUITING A Study of BGM-2121 in Patients With Advanced Solid Tumors
BioGate Precision Medicine Corp.
NCT06532565 RECRUITING Study of GS-2121 Given Alone or in Combination in Adults With Advanced Solid Tumors
Gilead Sciences
NCT05537740 ACTIVE NOT RECRUITING A First-in-human Study to Learn How Safe the Study Drug BAY3375968, an Anti-CCR8 Antibody, is, When Given Alone or in Combination With Pembrolizumab, How it Affects the Body, How it Moves Into, Through, and Out of the Body, and to Find the Best Dose in Participants With Advanced Solid Tumors
Bayer
NCT07524322 RECRUITING Study of RGT-490 in Patients With PIK3CA-Mutated Advanced Solid Tumors
Regor Pharmaceuticals Inc.
NCT07360314 RECRUITING Anti-Ly6E Exatecan ADC M7437 in Advanced Solid Tumors
EMD Serono Research & Development Institute, Inc.
NCT01590069 ACTIVE NOT RECRUITING Aerosolized Aldesleukin in Treating Patients With Lung Metastases
M.D. Anderson Cancer Center
NCT06884618 RECRUITING A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Clinical Activity of RO7673396 in Participants With Advanced Solid Tumors Harboring Rat Sarcoma Viral Oncogene Homolog (RAS) Mutation(s)
Hoffmann-La Roche
NCT07542704 NOT YET RECRUITING A Study to Investigate the Safety and Efficacy of KQB368 as Monotherapy in Participants With Advanced Solid Malignancies
Kumquat Biosciences Inc.
NCT06997029 RECRUITING A Phase 1 Study of BMS-986500 as Monotherapy or Combination Therapy in Advanced Solid Tumors
Bristol-Myers Squibb
NCT06586957 RECRUITING A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors
NiKang Therapeutics, Inc.
NCT06964009 RECRUITING DT2216 + Paclitaxel in Platinum-Resistant Ovarian Cancer
Elizabeth Stover, MD, PhD
NCT07541534 NOT YET RECRUITING A Phase I Clinical Study of HLX316 in Participants With Advanced/Metastatic Solid Tumors
Shanghai Henlius Biotech
NCT05571839 ACTIVE NOT RECRUITING A Study of PF-08046049/SGN-BB228 in Advanced Melanoma and Other Solid Tumors
Seagen, a wholly owned subsidiary of Pfizer
NCT07539285 RECRUITING A Study of HDM2024 in Participants With Advanced Solid Tumors
Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.
NCT04855656 RECRUITING Study of Lunresertib Alone or in Combination With RP-3500 or Debio 0123 in Patients With Advanced Solid Tumors
Debiopharm International SA
NCT07482592 RECRUITING Clinical Trial of TQB3205 Capsule in Subjects With Advanced Malignant Tumors
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT05208762 RECRUITING A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors
Seagen, a wholly owned subsidiary of Pfizer
NCT06270706 RECRUITING A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors
Pliant Therapeutics, Inc.
NCT06892379 RECRUITING A Study of HS-20110 in Participants With Advanced Solid Tumors
Hansoh BioMedical R&D Company
NCT06561685 RECRUITING A Study of LY4050784 in Participants With Advanced or Metastatic Solid Tumors
Eli Lilly and Company
NCT07538648 RECRUITING A Phase II Clinical Study Evaluating the Effectiveness of Injectable NC527-X in Intraoperative Imaging for Patients With Solid Tumors
Zhejiang Cancer Hospital
NCT06326411 RECRUITING A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors
Nested Therapeutics, Inc
NCT06131840 RECRUITING A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors
Seagen, a wholly owned subsidiary of Pfizer
NCT06447662 RECRUITING A Study to Learn About the Study Medicine PF-07934040 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Genetic Mutation.
Pfizer
NCT07538479 NOT YET RECRUITING Controlled Cold Exposure Combined With PD-1/PD-L1 Immunotherapy in Solid Tumors (NIVALIS)
West China Hospital
NCT06034002 RECRUITING A Study to Evaluate INCA033989 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasms
Incyte Corporation
NCT07114601 RECRUITING A Study of LY4257496 in Participants With Cancer (OMNIRAY)
Eli Lilly and Company
NCT07127874 RECRUITING A Study of PHN-012 in Patients With Advanced Solid Tumors
Pheon Therapeutics
NCT07218913 RECRUITING Testing the Addition of Pedmark to Cisplatin Chemotherapy for Reducing Drug-Induced Ear Damage in Men With Stage II-III Metastatic Testicular Germ Cell Tumors
City of Hope Medical Center
NCT07046923 RECRUITING A Study of LY4175408 in Participants With Advanced Cancer
Eli Lilly and Company
NCT06545942 ACTIVE NOT RECRUITING Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors
MOMA Therapeutics
NCT06544655 ACTIVE NOT RECRUITING A Study of BMS-986484 Alone and Combination Therapy in Participants With Advanced Solid Tumors
Bristol-Myers Squibb
NCT04503278 RECRUITING A Clinical Study of the Safety and Effectiveness of an Investigational Cell Therapy Given With and Without an Investigational RNA-based Vaccine in Patients With Organ Tumors
BioNTech Cell & Gene Therapies GmbH
NCT07213791 RECRUITING A Study of LY4337713 in Participants With FAP-Positive Solid Tumors
Eli Lilly and Company
NCT06597721 RECRUITING ADCE-T02, a Tissue Factor Targeted Antibody-Drug Conjugate, in Patients With Selected Advanced Solid Tumours
Adcendo ApS
NCT06307795 RECRUITING A Study to Investigate ANS014004 in Participants With Locally Advanced or Metastatic Solid Tumors
Avistone Biotechnology Co., Ltd.
NCT07258836 RECRUITING A Study of [18F]LY4214835 in Healthy Volunteers and Participants With Cancer
Eli Lilly and Company
NCT06576037 RECRUITING Phase Ib Study of CBP-1019 in Combination With FOLFOX +/- Bevacizumab, Pembrolizumab, or Enzalutamide for Metastatic TRPV6-overexpressing Solid Tumors of Epithelial Origin
M.D. Anderson Cancer Center
NCT03922555 RECRUITING ASTX727 in Recurrent/Progressive Non-enhancing IDH Mutant Gliomas
Massachusetts General Hospital
NCT03133650 ACTIVE NOT RECRUITING A Trial of a New Type of Photodynamic Therapy (VTP) in the Treatment of Patients With Cancer of the Esophagus Who Have Trouble Swallowing
Memorial Sloan Kettering Cancer Center
NCT07533708 NOT YET RECRUITING A Phase I Clinical Study of HLX3902 in Patients With mCRPC and Other Advanced Tumours
Shanghai Henlius Biotech
NCT06082960 ACTIVE NOT RECRUITING Study of GS-9911 With or Without Antibody Treatment for Adults With Solid Tumors
Gilead Sciences
NCT01187199 ACTIVE NOT RECRUITING Phase I Trial of Bevacizumab and Temsirolimus in Combination With 1) Carboplatin, 2) Paclitaxel, 3) Sorafenib for the Treatment of Advanced Cancer
M.D. Anderson Cancer Center
NCT06959706 RECRUITING Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of TGW101 in Participants With Advanced Solid Tumors
Tagworks Pharmaceuticals BV
NCT03435952 ACTIVE NOT RECRUITING Pembrolizumab With Intratumoral Injection of Clostridium Novyi-NT
M.D. Anderson Cancer Center
NCT06049212 ACTIVE NOT RECRUITING Sacituzumab Tirumotecan (MK-2870) as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors (MK-2870-008)
Merck Sharp & Dohme LLC
NCT07380334 RECRUITING A Clinical Study on the Safety, Tolerability, Pharmacokinetics and Efficacy of SHR-1049 in Patients With Advanced Solid Tumors
Jiangsu HengRui Medicine Co., Ltd.
NCT06066424 RECRUITING Phase 1 Dose Escalation and Expansion Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells in Patients With Advanced Solid Tumors (TROPIKANA)
M.D. Anderson Cancer Center
NCT05497778 ACTIVE NOT RECRUITING A Phase 1b Study of Gemcitabine and Nab-paclitaxel in Combination With IM156 in Patients With Advanced Pancreatic Cancer.
M.D. Anderson Cancer Center
NCT07229313 RECRUITING A Study of KIVU-107 in Participants With Locally Advanced or Metastatic Solid Tumors
Kivu Bioscience Inc.
NCT03634267 ACTIVE NOT RECRUITING MRI-Guided Brachytherapy in Treating Participants With HPV-Associated Stage IB2-IVA Cervical or Stage II-IVA Vaginal Cancer
M.D. Anderson Cancer Center
NCT07441694 RECRUITING Study of INCA036978 in Participants With Myeloproliferative Neoplasms
Incyte Corporation
NCT03114462 RECRUITING Trial of Stereotactic HYpofractionateD RadioAblative (HYDRA) Treatment of Laryngeal Cancer
M.D. Anderson Cancer Center
NCT05483868 RECRUITING A Phase 1, Open-label Trial of Belzupacap Sarotalocan (AU-011) in Bladder Cancer
Aura Biosciences
NCT07532018 RECRUITING DXP-106 in Solid Tumor Patients.
Singlomics Biopharmaceuticals Zhuhai Co., Ltd.
NCT06049576 ACTIVE NOT RECRUITING Nivolumab and Ipilimumab With and Without Camu Camu for the Treatment of Patients With Metastatic Renal Cell Carcinoma
City of Hope Medical Center
NCT06545331 RECRUITING Study of XB010 in Subjects With Solid Tumors
Exelixis
NCT05039801 RECRUITING IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors
M.D. Anderson Cancer Center
NCT06974110 RECRUITING Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors
MOMA Therapeutics
NCT03162627 ACTIVE NOT RECRUITING Selumetinib and Olaparib in Solid Tumors
M.D. Anderson Cancer Center
NCT07094204 RECRUITING A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors
Astellas Pharma Inc
NCT01481532 NOT YET RECRUITING Open Label Clinical Trial of Intravenous Crotoxin Part 3
Celtic Biotech Ltd
NCT06233942 RECRUITING Phase 1a/1b First-in-Human Study of BG-C9074 Alone and in Combination With Other Anticancer Therapies in Patients With Advanced Solid Tumors
BeOne Medicines
NCT04897321 RECRUITING B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)
St. Jude Children's Research Hospital
NCT06803680 RECRUITING A Study of BGB-B455 in Adults With Advanced or Metastatic Solid Tumors
BeiGene
NCT06120283 RECRUITING BGB-43395 Alone or as Part of Combination Therapies in Participants With Breast Cancer and Other Advanced Solid Tumors
BeOne Medicines
NCT07518043 NOT YET RECRUITING A Study of HLX18 vs. OPDIVO® in Multiple Resected Solid Tumors
Shanghai Henlius Biotech
NCT07362888 RECRUITING First-in-Human Study of ADCE-B05 in Patients With Advanced Solid Tumors
Adcendo ApS
NCT05718895 RECRUITING A Study of ATG-022 in Patients With Advanced/Metastatic Solid Tumors
Antengene Biologics Limited
NCT07395258 RECRUITING A Study to Test Different Doses of BI 3923948 Alone and in Combination With an Anti-PD-1 Antibody in People With Different Types of Advanced Cancer (Solid Tumors)
Boehringer Ingelheim
NCT05238922 RECRUITING Study of INCB123667 in Subjects With Advanced Solid Tumors
Incyte Corporation
NCT05430373 RECRUITING GT101 Injection for the Treatment of Metastatic or Recurrent Solid Tumors
Grit Biotechnology
NCT05071846 ACTIVE NOT RECRUITING MVX-ONCO-2 in Advanced Solid Tumors
University Hospital, Geneva
NCT06026410 RECRUITING KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors
Kura Oncology, Inc.
NCT06220864 RECRUITING SNV1521 in Participants With Advanced Solid Tumors
Synnovation Therapeutics, Inc.
NCT06001788 RECRUITING Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia
Kura Oncology, Inc.
NCT05382559 RECRUITING A Study of ASP3082 in Adults With Advanced Solid Tumors
Astellas Pharma Inc
NCT05377996 RECRUITING A Study of XMT-1660 in Participants With Solid Tumors
Mersana Therapeutics
NCT06718621 RECRUITING A Study of BL-M08D1 in Patients With Locally Advanced or Metastatic Solid Tumors
Sichuan Baili Pharmaceutical Co., Ltd.
NCT04847063 RECRUITING Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal Histologies
National Cancer Institute (NCI)
NCT07284186 RECRUITING First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors
Plexium, Inc.
NCT04533750 ACTIVE NOT RECRUITING Testing the Addition of M3814 (Peposertib) to Radiation Therapy for Patients With Advanced Head and Neck Cancer Who Cannot Take Cisplatin
National Cancer Institute (NCI)
NCT04520711 ACTIVE NOT RECRUITING Hotspot TCR-T: A Phase I/Ib Study of Adoptively Transferred T-cell Receptor Gene-engineered T Cells (TCR-T)
Providence Health & Services
NCT02381561 ACTIVE NOT RECRUITING Ropidoxuridine in Treating Patients With Advanced Gastrointestinal Cancer Undergoing Radiation Therapy
National Cancer Institute (NCI)
NCT01480154 ACTIVE NOT RECRUITING Akt Inhibitor MK2206 and Hydroxychloroquine in Treating Patients With Advanced Solid Tumors, Melanoma, Prostate or Kidney Cancer
National Cancer Institute (NCI)
NCT07524140 NOT YET RECRUITING Study of ZE94-0605 in Patients With Advanced Solid Tumors, With Dose Expansion Cohorts.
Eilean Therapeutics
NCT07408258 NOT YET RECRUITING Safety, Pharmacokinetics (PK), and Efficacy of ONC-783 in Advanced Solid Tumors
OncoC4, Inc.
NCT01366144 ACTIVE NOT RECRUITING Veliparib, Paclitaxel, and Carboplatin in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery and Liver or Kidney Dysfunction
National Cancer Institute (NCI)
NCT04470024 RECRUITING Phase Ib Trial of Multivalent Autophagosome Vaccine With or Without GITR Agonist, With Anti-PD-1 Immunotherapy in HNSCC
Providence Health & Services
NCT05509790 ACTIVE NOT RECRUITING A Study of LY3484356 in Chinese Participants With Advanced Breast Cancer
Eli Lilly and Company
NCT07040943 RECRUITING Clinical Trial of IL - 22BP Safety, Tolerability, and Antitumor Activity in Refractory Solid Tumors.
West China Hospital
NCT06352359 RECRUITING Safety, Pharmacokinetics (PK), and Efficacy of ONC 841 in Advanced Solid Tumors
OncoC4, Inc.
NCT03911388 RECRUITING HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors
M.D. Anderson Cancer Center
NCT06487624 RECRUITING An Engineered Sirpα Fused to Anti-Pd-L1 And Tgf-β Fusion Protein (HCB301) in Subjects With Selected Advanced Tumors
FBD Biologics Limited
NCT06403436 ACTIVE NOT RECRUITING A Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of TT125-802 in Subjects With Advanced Solid Tumors
TOLREMO therapeutics AG
NCT06625775 RECRUITING Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors
TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)
NCT07217171 RECRUITING A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas
EvolveImmune United, Inc
NCT02503722 ACTIVE NOT RECRUITING Testing the Combination of MLN0128 (TAK-228) and AZD9291 in Advanced EGFR (Epidermal Growth Factor Receptor) Mutation Positive Non-small Cell Lung Cancer
National Cancer Institute (NCI)
NCT04491942 ACTIVE NOT RECRUITING Testing the Addition of an Anti-cancer Drug, BAY 1895344, to the Usual Chemotherapy Treatment (Cisplatin, or Cisplatin and Gemcitabine) for Advanced Solid Tumors With Emphasis on Urothelial Cancer
National Cancer Institute (NCI)
NCT06515613 RECRUITING A Phase 1 Study of CTIM-76 in Patients With Recurring Ovarian Cancer and Other Advanced Solid Tumors
Context Therapeutics Inc.
NCT06582017 RECRUITING Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma
Nammi Therapeutics Inc
NCT02627443 ACTIVE NOT RECRUITING Carboplatin, Gemcitabine Hydrochloride, and Berzosertib in Treating Patients With Recurrent and Metastatic Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
National Cancer Institute (NCI)
NCT02015117 ACTIVE NOT RECRUITING Trametinib With or Without Whole Brain Radiation Therapy in Treating Patients With Brain Metastases
National Cancer Institute (NCI)
NCT07525141 RECRUITING A Study of JNJ-1761981 in Participants With Solid Tumors
Johnson & Johnson Enterprise Innovation Inc.
NCT06238479 ACTIVE NOT RECRUITING A Study of LY4101174 in Participants With Recurrent, Advanced or Metastatic Solid Tumors
Eli Lilly and Company
NCT06960395 RECRUITING Safety and Preliminary Efficacy of VIR-5525 and VIR-5525 + Pembrolizumab in Participants With Locally Advanced or Metastatic Solid Tumors
Vir Biotechnology, Inc.
NCT06143774 RECRUITING Study of TRX-920 for Patients With Advanced Solid Tumors
TaiRx, Inc.
NCT07165132 RECRUITING Study of RYZ401 in Subjects With Solid Tumors Expressing SSTRs.
RayzeBio, Inc.
NCT06253871 RECRUITING A Phase 1/1b Study of IAM1363 in HER2 Cancers
Iambic Therapeutics, Inc
NCT07519564 NOT YET RECRUITING A Phase I Clinical Study to Evaluate the PK, PD, Efficacy, and Safety of GB18 Injection in Patients With Tumor Cachexia
Kexing Biopharm Co., Ltd.
NCT06832982 RECRUITING Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacokinetics, and Preliminary Efficacy of FS-8002
Shanghai Pushi Medical Science Co. Ltd
NCT07190833 RECRUITING A Phase 1 Study of OTS-412 (Recombinant Oncolytic Vaccinia Virus) in Treatment-refractory Solid Tumor Patients (South Korea)
Bionoxx Inc.
NCT05858736 ACTIVE NOT RECRUITING Safety, PK and Efficacy of AI-061 in Advanced Solid Tumors
OncoC4, Inc.
NCT06672523 RECRUITING A Study to Evaluate the Mass Balance, Metabolism, Elimination, and Drug Levels of [14C]-BMS-986504 (MRTX1719) in Participants With Advanced Solid Tumors With Homozygous Methylthioadenosine Phosphorylase Deletion
Bristol-Myers Squibb
NCT03594422 RECRUITING A Study of HQP1351 in Patients With GIST or Other Solid Tumors
Ascentage Pharma Group Inc.
NCT07141706 RECRUITING A Study of DB-1317 in Selected Advanced/Metastatic Solid Tumors
DualityBio Inc.
NCT04794699 ACTIVE NOT RECRUITING Study of IDE397 in Participants With Solid Tumors Harboring MTAP Deletion
IDEAYA Biosciences
NCT05635591 ENROLLING BY INVITATION KSD-101 Therapy for EBV-associated Haematologic Neoplasms: an Exploratory Clinical Trial
Tongji Hospital
NCT07517198 RECRUITING Dose Determining Study of EXS74539 (REC-4539) in Participants With Select Solid Tumors
Exscientia AI Ltd., a wholly owned subsidiary of Recursion Pharmaceuticals, Inc.
NCT05462717 ACTIVE NOT RECRUITING Dose Escalation and Dose Expansion Study of RMC-6291 Monotherapy in Subjects With Advanced KRASG12C Mutant Solid Tumors
Revolution Medicines, Inc.
NCT05003895 RECRUITING GPC3 Targeted CAR-T Cell Therapy in Advanced GPC3 Expressing Solid Tumor Malignancies
National Cancer Institute (NCI)
NCT04516447 RECRUITING A Study of Azenosertib (ZN-c3) in Patients With Ovarian Cancer
K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc
NCT06444815 RECRUITING A Study of VET3-TGI in Patients With Solid Tumors
KaliVir Immunotherapeutics
NCT07054307 RECRUITING MRG003 Plus HX008 as First-Line Treatment for EGFR-Positive Locally Advanced or Metastatic Penile Squamous Cell Carcinoma
Jiyan Liu
NCT07090499 RECRUITING A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors
Pfizer
NCT05861895 RECRUITING HF158K1 in Patients With HER-2 Expressing Advanced Solid Tumors
HighField Biopharmaceuticals Corporation
NCT04044859 ACTIVE NOT RECRUITING ADP-A2M4CD8 as Monotherapy or in Combination With Either Nivolumab or Pembrolizumab in HLA-A2+ Subjects With MAGE-A4 Positive Tumors (SURPASS)
USWM CT, LLC
NCT07170592 NOT YET RECRUITING A Phase 1 Study of OTS-412 (Recombinant Oncolytic Vaccinia Virus) in Treatment-refractory Solid Tumor Patients
Bionoxx Inc.
NCT07424547 RECRUITING Phase I Study of SYS6043 in Patients With Advanced/Metastatic Solid Tumors
Conjupro Biotherapeutics, Inc.
NCT07426757 NOT YET RECRUITING An Open-Label Study to Evaluate PF-07994525 in Participants With Advanced Cancers
Pfizer
NCT02637934 RECRUITING Phase I Pilot Study of Biodistribution, Metabolism and Excretion of Novel Radiotracer [18F]Fluorthanatrace (FTT) by PET/CT
Abramson Cancer Center at Penn Medicine
NCT07438782 RECRUITING First Time in Human (FTIH) Study to Investigate the Safety and Preliminary Activity of GSK5533524 Alone or in Combination in Adult Participants With Advanced Solid Tumors
GlaxoSmithKline
NCT06773091 RECRUITING A Phase I Study of NK042 Cell Injection in Advanced Solid Tumors
Shanghai NK Cell Technology Co., LTD
NCT06657144 RECRUITING A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors
Coherus Oncology, Inc.
NCT07455617 RECRUITING Study of ABO2102 in KRAS-Mutated Solid Tumors
Suzhou Abogen Biosciences Co., Ltd.
NCT06422520 ACTIVE NOT RECRUITING A First-in-Human Study of BGB-C354 Alone and in Combination With Tislelizumab in Participants With Advanced Solid Tumors
BeOne Medicines
NCT07008118 RECRUITING A Study to Evaluate INCA035784 in Participants With Myeloproliferative Neoplasms
Incyte Corporation
NCT06672185 RECRUITING ARC101 in Advanced Solid Tumors
Third Arc Bio
NCT06878248 ACTIVE NOT RECRUITING A Study to Assess CLBR001+ABBV-461 in Subjects With Locally Advanced or Metastatic Breast Cancer
Calibr, a division of Scripps Research
NCT02937272 ACTIVE NOT RECRUITING A Study of LY3200882 in Participants With Solid Tumors
Eli Lilly and Company
NCT07277413 RECRUITING A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors
IDEAYA Biosciences
NCT05752552 RECRUITING Study to Determine the Safety and Pharmacokinetics of DO-2 in Patients With Advanced or Refractory Solid Tumours
DeuterOncology
NCT07144085 RECRUITING Application of ⁶⁸Ga-FXX489 (NNS309) PET/CT Imaging in Diagnosis of Tumor Diseases.
Yi Tian
NCT06342986 ACTIVE NOT RECRUITING Intraperitoneal FT536 in Recurrent Ovarian, Fallopian Tube, and Primary Peritoneal Cancer
Masonic Cancer Center, University of Minnesota
NCT06451497 RECRUITING This is a Phase 1 Trial of ZM008, an Anti-LLT1 Antibody, Used as Single Agent Followed by Combination Treatment With Toripalimab in Patients With Advanced Solid Tumors
Zumutor Biologics Inc.
NCT05521984 RECRUITING Targeting Pediatric Brain Tumors and Relapsed/Refractory Solid Tumors With Sodium Glucose Cotransporter 2 Inhibitors (SGLT2i)
Washington University School of Medicine
NCT07402915 RECRUITING Drug-drug Interaction Study With AZD5335 and Itraconazole in Participants With Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
AstraZeneca
NCT04893434 ACTIVE NOT RECRUITING Novel Imaging Technique to Assess Gynecologic Cancer
Memorial Sloan Kettering Cancer Center
NCT05614102 ACTIVE NOT RECRUITING A First-in-human Study to Learn How Safe the Study Drug BAY2965501 is, Find the Best Dose (Single Drug & Combination), How it Affects the Body, What Maximum Amount Can be Given, How it Moves Into, Through and Out of the Body, How it Acts on Different Tumors in Participants With Advanced Solid Tumors
Bayer
NCT05891171 ACTIVE NOT RECRUITING Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers
Arcus Biosciences, Inc.
NCT07503808 RECRUITING A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types
IDEAYA Biosciences
NCT07176975 NOT YET RECRUITING A Study to Test How Well Different Doses of BI 1831169 in Combination With an Anti-PD1 Antibody Are Tolerated in Japanese People With Different Advanced Cancers
Boehringer Ingelheim
NCT06770569 RECRUITING A Clinical Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of HRS-3802 Monotherapy in Patients With Malignant Solid Tumors
Shandong Suncadia Medicine Co., Ltd.
NCT04722523 RECRUITING A Study of Cemiplimab With Chemotherapy and Immunotherapy in People With Head and Neck Cancer
Memorial Sloan Kettering Cancer Center
NCT03860272 ACTIVE NOT RECRUITING Fc-Engineered Anti-CTLA-4 Monoclonal Antibody in Advanced Cancer
Agenus Inc.
NCT04197934 ACTIVE NOT RECRUITING WSD0922-FU for the Treatment of Glioblastoma, Anaplastic Astrocytoma, or Non-small Cell Lung Cancer With Central Nervous System Metastases
Mayo Clinic
NCT04328844 ACTIVE NOT RECRUITING A Study to Assess a PI3Kδ Inhibitor (IOA-244) in Patients With Metastatic Cancers
iOnctura
NCT05753501 ACTIVE NOT RECRUITING Study to Evaluate Adverse Events, Change in Disease Activity, and How Oral ABBV-101 Moves Through the Body in Adult Participants With B-Cell Malignancies
AbbVie
NCT05763004 ACTIVE NOT RECRUITING A Clinical Study to Evaluate the Safety, Tolerability and Efficacy of IOS-1002 Administered Alone and in Combination With Pembrolizumab, a PD-1 Monoclonal Antibody in Advanced Solid Tumors
ImmunOs Therapeutics AG
NCT06687941 RECRUITING A Study to Evaluate the Tolerability, Safety, and PK of AST-201 in Patients With GPC3-positive Advanced Solid Tumors
Aptamer Sciences, Inc.
NCT05017012 ACTIVE NOT RECRUITING A Study to Evaluate the Bioavailability of Pembrolizumab (MK-3475) Via Subcutaneous (SC) Injection of Pembrolizumab Formulated With Berahyaluronidase Alfa (MK-5180) [MK-3475A] In Advanced Solid Tumors (MK-3475A-C18)
Merck Sharp & Dohme LLC
NCT05768932 RECRUITING BAL0891 in Patients With Advanced Solid Tumors or Relapsed or Refractory Acute Myeloid Leukemia
SillaJen, Inc.
NCT07383506 NOT YET RECRUITING A Study of Mutant Selective-Inhibitor (CGT6297), in Patients With Advanced Solid Tumors
Cogent Biosciences, Inc.
NCT04221204 ACTIVE NOT RECRUITING A Monotherapy in Subjects With Advanced Solid Tumors
3D Medicines (Beijing) Co., Ltd.
NCT04670679 ACTIVE NOT RECRUITING A Dose Escalation/Expansion Study of ERAS-601 in Patients With Advanced or Metastatic Solid Tumors
Erasca, Inc.
NCT06858813 RECRUITING A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused ABBV-324 in Adult Participants With Hepatocellular Cancer (HCC) or Squamous-Cell Non-Small Cell Lung Cancer (LUSC)
AbbVie
NCT07262164 RECRUITING A Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Biologic Effect of VG2062 in Patients With Solid Tumors
Shanghai Virogin Biotech Co., Ltd.
NCT06265688 RECRUITING First In Human Study of CX-2051 in Advanced Solid Tumors
CytomX Therapeutics
NCT06328439 ACTIVE NOT RECRUITING A Study to Evaluate ANS014004 in Subjects With Locally Advanced or Metastatic Solid Tumors
Avistone Biotechnology Co., Ltd.
NCT06421935 ACTIVE NOT RECRUITING M9466 Alone or in Combination in Advanced Solid Tumors (DDriver 501)
EMD Serono Research & Development Institute, Inc.
NCT06462794 RECRUITING First In Human Study of CX-801 in Advanced Solid Tumors
CytomX Therapeutics
NCT05936359 RECRUITING A Study to Evaluate INCA033989 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasms
Incyte Corporation
NCT04189614 ACTIVE NOT RECRUITING An Efficacy and Safety Study of Cofetuzumab Pelidotin in Participants With PTK7-Expressing, Recurrent Non-Small Cell Lung Cancer
AbbVie
NCT07490236 RECRUITING Trilaciclib in Combination With Chemotherapy in Patients With CDK4/6-Dependent Solid Tumors
Hebei Medical University Fourth Hospital
NCT05838768 ACTIVE NOT RECRUITING Study of HRO761 Alone or in Combination in Cancer Patients With Specific DNA Alterations Called Microsatellite Instability or Mismatch Repair Deficiency.
Novartis Pharmaceuticals
NCT06818812 ACTIVE NOT RECRUITING A Study to Evaluate INCB186748 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation
Incyte Corporation
NCT06667141 RECRUITING Phase 1 Study of ACR-2316 in Specific Advanced Solid Tumors
Acrivon Therapeutics
NCT06917079 RECRUITING BBO-11818 in Adult Subjects With KRAS Mutant Cancer
TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)
NCT04514484 ACTIVE NOT RECRUITING Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV
National Cancer Institute (NCI)
NCT05277051 ACTIVE NOT RECRUITING First-Time-in-Human Study of GSK4381562 in Participants With Advanced Solid Tumors
GlaxoSmithKline
NCT07482319 NOT YET RECRUITING A Clinical Study GK01 Injection in Subjects With Advanced Malignant Solid Tumors
Beijing Geekgene Technology Co., LTD
NCT03044613 ACTIVE NOT RECRUITING Nivolumab +/- Relatlimab Prior to Chemoradiation With II/III Gastro/Esophageal Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT06293898 RECRUITING Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors
SystImmune Inc.
NCT07015697 RECRUITING A Study of Subcutaneous Trastuzumab Deruxtecan in Participants With Metastatic Solid Tumors
Daiichi Sankyo
NCT05720117 RECRUITING A Study of PYX-201 in Advanced Solid Tumors
Pyxis Oncology, Inc
NCT04419532 ACTIVE NOT RECRUITING A Study Evaluating DS-1055a in Participants With Relapsed or Refractory Locally Advanced or Metastatic Solid Tumors
Daiichi Sankyo
NCT07182591 RECRUITING A Study of DS5361b in Participants With Advanced Solid Tumors
Daiichi Sankyo
NCT05143970 RECRUITING A Phase 1 First-In-Human Study of the Anti-CD73 IPH5301 Alone or in Combination With Chemotherapy and Trastuzumab in Patients With Advanced Solid Tumors
Institut Paoli-Calmettes
NCT05948865 RECRUITING A Phase 1 Study of CPO301 in Adult Patients With Advanced or Metastatic Solid Tumors
Conjupro Biotherapeutics, Inc.
NCT06158139 RECRUITING Autologous CAR-T Cells Targeting B7-H3 in PDAC
UNC Lineberger Comprehensive Cancer Center
NCT05635643 RECRUITING Study of CHS-114 in Participants With Advanced Solid Tumors
Coherus Oncology, Inc.
NCT07128303 RECRUITING Study of GS-5319 in Adults With Solid Tumors
Gilead Sciences
NCT02789228 ACTIVE NOT RECRUITING Research Study Utilizing Expanded Multi-antigen Specific Lymphocytes for the Treatment of Solid Tumors
Children's National Research Institute
NCT04823897 RECRUITING A Phase I Open-Label, Single-Arm, Dose-Escalation Clinical and Pharmacology Study of CCI-001 as Monotherapy and in Combination With Standard Chemotherapy in Patients With Recurrent and/or Metastatic Solid Tumours
PharmaMatrix Holdings Ltd
NCT04192344 RECRUITING A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in Patients With Advanced Solid Tumor
Abbisko Therapeutics Co, Ltd
NCT05719558 RECRUITING A Study of ASP1002 in Adults for Treatment of Solid Tumors
Astellas Pharma Global Development, Inc.
NCT03478462 ACTIVE NOT RECRUITING Dose Escalation Study of CLR 131 in Pediatric Relapsed/Refractory Malignant Tumors Including Neuroblastoma and Sarcomas
Cellectar Biosciences, Inc.
NCT06248411 RECRUITING A Clinical Study of KK2260 in Patients With Advanced or Metastatic Solid Tumors
Kyowa Kirin Co., Ltd.
NCT04443088 RECRUITING An Open-Label Study of INV-1120 as a Single Agent and in Combination With Pembrolizumab in Adult Patients With Advanced Solid Tumors
Shenzhen Ionova Life Sciences Co., Ltd.
NCT06585488 RECRUITING A First-in-human Study of BGB-53038, a Pan-KRAS Inhibitor, Alone or in Combinations in Participants With Advanced or Metastatic Solid Tumors With KRAS Mutations or Amplification
BeiGene
NCT07480681 NOT YET RECRUITING Phase I Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of HLX97 (a KAT6A/B Inhibitor) in Patients With Advanced/Metastatic Solid Tumor
Shanghai Henlius Biotech
NCT07481357 RECRUITING A First-In-Human Phase I/IIa Study to Evaluate DA 3501 in Patients With Advanced Gastric or Gastro-esophageal Junction Adenocarcinoma and Pancreatic Ductal Adenocarcinoma
Dong-A ST Co., Ltd.
NCT06804824 RECRUITING A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-159642 in Participants With Advanced Solid Tumors
Vividion Therapeutics, Inc.
NCT05694715 RECRUITING Combination Therapy in Cancers With Mutations in DNA Repair Genes
University of California, San Francisco
NCT06927297 RECRUITING Phase I Study of the Safety, Tolerability, and Efficacy of an Engineered Mitochondrial Vaccine in Advanced Solid Tumors
West China Hospital
NCT07038369 ACTIVE NOT RECRUITING A Phase 1 Study of ATV-1601 in Patients With Advanced Cancer That Have AKT1 E17K Mutations
Atavistik Bio, Inc
NCT07477743 RECRUITING A Phase Ib Clinical Study on the Safety and Efficacy of HC010 Combinations in Advanced Solid Tumors
HC Biopharma Inc.
NCT07475559 NOT YET RECRUITING JSKN016HC in Patients With Advanced or Metastatic Solid Malignant Tumors
Jiangsu Alphamab Biopharmaceuticals Co., Ltd
NCT07473726 NOT YET RECRUITING A Phase I Clinical Study to Evaluate the Safety, Tolerability, and PK of HLX48 in Advanced/Metastatic Solid Tumors
Shanghai Henlius Biotech
NCT06716138 RECRUITING A Study to Investigate ANS03 in Participants With Locally Advanced or Metastatic Solid Tumors
Avistone Biotechnology Co., Ltd.
NCT07454031 NOT YET RECRUITING Intraperitoneal PX in Combination With Nab-Paclitaxel in Patients With Peritoneal Metastatic Mucinous Adenocarcinoma
Peking University
NCT05853367 RECRUITING Study of MK-0472 in Participants With Advanced/Metastatic Solid Tumors (MK-0472-001)
Merck Sharp & Dohme LLC
NCT05285358 RECRUITING Pressurized Intraperitoneal Aerosolized Nab-Paclitaxel in Combination With Gemcitabine and Cisplatin for the Treatment of Biliary Tract Cancer Patients With Peritoneal Metastases
City of Hope Medical Center
NCT06704724 ACTIVE NOT RECRUITING A Study to Learn About the Study Medicine PF-07985045 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Change in a Gene.
Pfizer
NCT05957536 RECRUITING A Study of D3L-001 as Monotherapy in Subjects With HER2-Positive Advanced Solid Tumors
D3 Bio (Wuxi) Co., Ltd
NCT07207707 RECRUITING A Study to Investigate the Safety and Efficacy of KQB548 in Participants With Advanced Solid Malignancies
Kumquat Biosciences Inc.
NCT05382364 ACTIVE NOT RECRUITING Safety and Pharmacokinetics of Tucatinib (MK-7119) in Chinese Participants With Cancer (MK-7119-002)
Pfizer
NCT07372625 RECRUITING A Study to Investigate the Effects of Multiple Doses of Rezatapopt on the Pharmacokinetics of Metformin, Rosuvastatin, Repaglinide, and Midazolam in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation.
PMV Pharmaceuticals, Inc
NCT07457541 ACTIVE NOT RECRUITING Molecular Imaging of Fibroblast Activation Protein Expression Using Labeled Technetium-99m HYNIC-FAPI
Tomsk National Research Medical Center of the Russian Academy of Sciences
NCT05238792 RECRUITING Multi Tumor-Associated Antigen-Specific T Lymphocytes to Treat Patients With High Risk Solid Tumors
Children's National Research Institute
NCT05176483 RECRUITING Study of Zanzalintinib in Combination With Immuno-Oncology Agents in Participants With Solid Tumors
Exelixis
NCT07467629 RECRUITING QLS5212 for Participants With Advanced Solid Tumors
Qilu Pharmaceutical Co., Ltd.
NCT06598800 RECRUITING Study of BG-T187 Alone and in Combination With Other Therapeutic Agents in Participants With Advanced Solid Tumors
BeiGene
NCT07029399 RECRUITING A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors
NiKang Therapeutics, Inc.
NCT06563375 RECRUITING Phase 1 Dose Escalation and Dose Expansion Trial of NP-101 in Patients With Solid Tumors
M.D. Anderson Cancer Center
NCT06234397 RECRUITING Dose Escalation and Expansion Study of BH3120 Alone or With Pembrolizuamb in Advanced or Metastatic Solid Tumors
Hanmi Pharmaceutical Company Limited
NCT03006172 ACTIVE NOT RECRUITING To Evaluate the Safety, Tolerability, and Pharmacokinetics of Inavolisib Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer
Genentech, Inc.
NCT04572295 ACTIVE NOT RECRUITING A Study of E7090 as Monotherapy and in Combination With Other Anticancer Agents in Participants With Estrogen Receptor Positive (ER+) and Human Epidermal Growth Receptor 2 Negative (HER2-) Recurrent/Metastatic Breast Cancer
Eisai Co., Ltd.
NCT03968406 RECRUITING Talazoparib and Radiation Therapy in Treating Patients With Locally Recurrent Gynecologic Cancers
M.D. Anderson Cancer Center
NCT07462442 NOT YET RECRUITING Study of QLS5308 in Patients With Advanced Solid Tumors
Qilu Pharmaceutical Co., Ltd.
NCT07460765 NOT YET RECRUITING Safety and Feasibility of Nivolumab-IRDye800CW in Patients With Head and Neck Squamous Cell Carcinoma (HNSCC)
Vanderbilt-Ingram Cancer Center
NCT06269978 RECRUITING Intraperitoneal Oxaliplatin and Fluorouracil for the Treatment of Patients With Peritoneal Metastases From Colorectal Cancer
Arjun Mittra
NCT05781048 ACTIVE NOT RECRUITING A Phase I Clinical Study of the Safety, Tolerability,Pharmacokinetics, and Initial Efficacy of HRS-6209 Monotherapy in Patients With Advanced Solid Tumors
Jiangsu HengRui Medicine Co., Ltd.
NCT06533059 RECRUITING A Study to Learn About Study Medicine ALTA2618 in Adults With AKT1 E17K-Mutant Solid Tumors
Alterome Therapeutics, Inc.
NCT03264664 ACTIVE NOT RECRUITING Study of E7386 in Participants With Selected Advanced Neoplasms
Eisai Inc.
NCT06171750 RECRUITING Phase I Study of Tolododekin Alfa (ANK-101) in Advanced Solid Tumors
Ankyra Therapeutics, Inc
NCT07454668 NOT YET RECRUITING Trastuzumab Deruxtecan + Stereotactic Radiosurgery (SRS) in HER2+ Breast Cancer Brain Metastases
Baptist Health South Florida
NCT05103631 ACTIVE NOT RECRUITING Interleukin-15 Armored Glypican 3-specific Chimeric Antigen Receptor Expressed in Autologous T Cells for Solid Tumors
Baylor College of Medicine
NCT05661201 RECRUITING NEROFE and Doxorubicin in KRAS-mutated ST2-positive Solid Tumors
Georgetown University
NCT07189949 RECRUITING A Study of HRS-2329 in Participants With Advanced Solid Tumors Harboring RAS Mutations or Amplifications
Jiangsu HengRui Medicine Co., Ltd.
NCT06508138 ENROLLING BY INVITATION Clinical Trial Assessing the Safety and Immunologic Correlates of Heterologous Prime-Boost With pNGVL4a-Sig/E7(Detox)/HSP70 and TA-HPV in Healthy Donors Followed by Peripheral Blood Collection
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT05122546 ACTIVE NOT RECRUITING CBM588 in Combination With Nivolumab and Cabozantinib for the Treatment of Advanced or Metastatic Kidney Cancer
City of Hope Medical Center
NCT01970722 ACTIVE NOT RECRUITING Surgery and Chemotherapy With or Without Chemotherapy After Surgery in Treating Patients With Ovarian, Fallopian Tube, Uterine, or Peritoneal Cancer
City of Hope Medical Center
NCT07374848 RECRUITING Phase 1a/b Study of ZL-6201 Safety, PK, and Preliminary Efficacy in Sarcoma and Selected Tumors
Zai Lab (Shanghai) Co., Ltd.
NCT04928508 RECRUITING Advanced or Recurrent Solid Tumors Treated With SHetA2
University of Oklahoma
NCT04661384 ACTIVE NOT RECRUITING Brain Tumor-Specific Immune Cells (IL13Ralpha2-CAR T Cells) for the Treatment of Leptomeningeal Glioblastoma, Ependymoma, or Medulloblastoma
City of Hope Medical Center
NCT04900818 RECRUITING Study of TJ033721 (Givastomig) in Subjects With Advanced or Metastatic Solid Tumors
I-Mab Biopharma US Limited
NCT06868433 RECRUITING TMV Vaccine Therapy Alone and With Pembrolizumab for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer
Emory University
NCT06251544 NOT YET RECRUITING TRAIL-R2 and HER2 Bi-Specific Chimeric Antigen Receptor (CAR) T Cells for the Treatment of Metastatic Breast Cancer
Baylor College of Medicine
NCT06713369 RECRUITING AZD5305 hADME in Patients With Advanced Solid Malignancies
AstraZeneca
NCT03313778 ACTIVE NOT RECRUITING Safety, Tolerability, and Immunogenicity of mRNA-4157 Alone and in Combination in Participants With Solid Tumors
ModernaTX, Inc.
NCT06321484 RECRUITING Intraperitoneal Cytokine-Induced Memory Like (CIML) Natural Killer (NK) Cells in Recurrent Ovarian Cancer
Dana-Farber Cancer Institute
NCT07297160 NOT YET RECRUITING CD70.CAR for CD70+ Lymphoma, Myeloma and Solid Tumors
Baylor College of Medicine
NCT07447856 RECRUITING A Study Testing Topical Pain-Relieving Herbal Plasters in People Who Are Using Opioids for Their Pain
Memorial Sloan Kettering Cancer Center
NCT07046559 RECRUITING A Single- and Multiple-Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of LY4066708 in Healthy Participants
Eli Lilly and Company
NCT05873686 RECRUITING A Phase 1 Clinical Study of NXP900 in Subjects With Advanced Cancers
Nuvectis Pharma, Inc.
NCT03207672 ACTIVE NOT RECRUITING Study of E7389 Liposomal Formulation in Participants With Solid Tumor
Eisai Co., Ltd.
NCT07321106 RECRUITING A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer
Cartography Biosciences
NCT06537310 ACTIVE NOT RECRUITING A Dose-escalation Study of RO7567132 as Single Agent and in Combination With Atezolizumab in Participants With Advanced Solid Tumors
Hoffmann-La Roche
NCT07446816 RECRUITING A Clinical Study Evaluating the Preliminary Anti-tumor Efficacy and Safety of Hemay181
Ganzhou Hemay Pharmaceutical Co., Ltd
NCT03391778 RECRUITING Adoptive Cell Therapy Long-term Follow-up (LTFU) Study
USWM CT, LLC
NCT06994806 RECRUITING A Study to Investigate the Safety and Efficacy of KQB168 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies
Kumquat Biosciences Inc.
NCT07304128 RECRUITING A Study of PLB-002 in Advanced Solid Tumors
Primelink BioTherapeitics(ShenZhen) Limited
NCT07064122 RECRUITING A Study of AZD2962, an IRAK4 Inhibitor (IRAK4 [a Body Protein] Blocker), in Participants With Haematologic Neoplasms (Blood Cancers)
AstraZeneca
NCT02721459 ACTIVE NOT RECRUITING XL888 + Vemurafenib + Cobimetinib for Unresectable BRAF Mutated Stage III/IV Melanoma
H. Lee Moffitt Cancer Center and Research Institute
NCT06715124 ACTIVE NOT RECRUITING QTX3544 in Patients With Advanced Solid Tumors With KRAS G12V Mutations
Quanta Therapeutics
NCT07269080 RECRUITING STM-06: POLARIS-POlymetastic Lesion Ablative Radiotherapy With Immunotherapy Study
University of Illinois at Chicago
NCT04473781 RECRUITING Interstitial Brachytherapy for the Treatment of Unresectable/Unablatable Kidney Cancer
Jonsson Comprehensive Cancer Center
NCT06612645 RECRUITING Safety and Efficacy of CMD03 CAR T Cell in Children With Relapse or Refractory Solid Tumors
Chulalongkorn University
NCT04336241 ACTIVE NOT RECRUITING Study of RP2 Monotherapy and RP2 in Combination With Nivolumab in Patients With Solid Tumors
Replimune, Inc.
NCT06759649 RECRUITING A Clinical Trial to Assess COM503 in Participants With Advanced Solid Malignancies
Compugen Ltd
NCT07382817 RECRUITING Phase 1 Study of JV-394 Autologous Anti-CD94 CAR T for r/r CD94+ T/NK Cell Neoplasms
M.D. Anderson Cancer Center
NCT06402201 RECRUITING First in Human Study of CDR404 in HLA-A*02:01 Participants With MAGE-A4 Expressing Solid Tumors
CDR-Life AG
NCT04735978 ACTIVE NOT RECRUITING Study of RP3 Monotherapy and RP3 in Combination With Nivolumab in Patients With Solid Tumours
Replimune, Inc.
NCT03833700 ACTIVE NOT RECRUITING A Study of E7386 in Participants With Advanced Solid Tumor Including Colorectal Cancer (CRC)
Eisai Co., Ltd.
NCT07361562 RECRUITING A Study of a Selective ERBB2 Inhibitor (CGT4255), in Patients With Advanced Solid Tumors
Cogent Biosciences, Inc.
NCT05914376 ACTIVE NOT RECRUITING Safety of Recombinant Human IL-21-expressing Oncolytic Vaccinia Virus Injection (hV01) in Advanced Tumors
Hangzhou Converd Co., Ltd.
NCT04288089 ACTIVE NOT RECRUITING A Study of H3B-6545 in Combination With Palbociclib in Women With Advanced or Metastatic Estrogen Receptor-Positive Human Epidermal Growth Factor Receptor-2 (HER2)-Negative Breast Cancer
Eisai Inc.
NCT03448042 ACTIVE NOT RECRUITING A Study of Runimotamab in Participants With Locally Advanced or Metastatic HER2-Expressing Cancers
Genentech, Inc.
NCT05907304 ACTIVE NOT RECRUITING A Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With RAS Q61X Mutations
Erasca, Inc.
NCT03830320 RECRUITING Positron Emission Tomography (PET) Imaging of Thrombosis
Massachusetts General Hospital
NCT07279428 RECRUITING A Study of BL-M24D1 in Patients With Locally Advanced or Metastatic Gastrointestinal Tumors and Other Solid Tumors
Sichuan Baili Pharmaceutical Co., Ltd.
NCT03203525 ACTIVE NOT RECRUITING Combination Chemotherapy and Bevacizumab With the NovoTTF-100L(P) System in Treating Participants With Advanced, Recurrent, or Refractory Hepatic Metastatic Cancer
M.D. Anderson Cancer Center
NCT07434609 NOT YET RECRUITING Evaluation of T320, an Anti-Tissue Factor Antibody-Drug Conjugate, in Patients With Advanced Solid Tumors
Nanolattix Biotechnology Co., Ltd.
NCT07030959 RECRUITING Study of AUBE00 in Patients With Solid Tumors
Chugai Pharmaceutical
NCT06104488 RECRUITING A Study of Avutometinib for People With Solid Tumor Cancers
Memorial Sloan Kettering Cancer Center
NCT06521554 RECRUITING A Study of NVL-330 in Patients With Advanced or Metastatic HER2-altered NSCLC (HEROEX-1)
Nuvalent Inc.
NCT07382544 RECRUITING Phase 1b Trial of BMS-986504 in Combination With Olaparib in Patients With MTAP Loss
M.D. Anderson Cancer Center
NCT07156136 RECRUITING Study of IMC-P115C in Advanced PRAME-Positive Cancers
Immunocore Ltd
NCT04250155 ACTIVE NOT RECRUITING An Open-Label Dose-Escalation Study to Evaluate XmAb24306 as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors
Genentech, Inc.
NCT06799065 RECRUITING First-in-Human Study of ATX-295, an Oral Inhibitor of KIF18A, in Patients With Advanced or Metastatic Solid Tumors, Including Ovarian Cancer
Accent Therapeutics
NCT07190469 RECRUITING PQ203 in Advanced Malignant Tumors Including Triple Negative Breast Cancer
ProteinQure Inc.
NCT05753722 RECRUITING A First-in-human Study of PRTH-101 Monotherapy +/- Pembrolizumab in Subjects With Advanced Malignancies
Incendia Therapeutics
NCT07108114 RECRUITING SLV-324 Treatment of Metastatic Solid Tumors
Solve Therapeutics
NCT00750841 ACTIVE NOT RECRUITING Study of the Effect of Rifampicin on the Pharmacokinetics (PK) of Multiple Doses of Cediranib in Patients With Solid Tumours
AstraZeneca
NCT07423117 NOT YET RECRUITING A Study of ITC-6146RO in Patients With Advanced or Metastatic Cancer Who Have Failed Standard Therapy
IntoCell, Inc
NCT05527184 ACTIVE NOT RECRUITING First in Human Study of IMGN151 in Recurrent Gynaecological Cancers
AbbVie
NCT04649385 ACTIVE NOT RECRUITING BGB-15025 Alone and in Combination With Anti-PD-1 Monoclonal Antibody Tislelizumab in Participants With Advanced Solid Tumors
BeiGene
NCT05396833 ACTIVE NOT RECRUITING Study of Tuvusertib (M1774) in Combination With DNA Damage Response Inhibitor or Immune Checkpoint Inhibitor (DDRiver Solid Tumors 320)
EMD Serono Research & Development Institute, Inc.
NCT03252938 ACTIVE NOT RECRUITING Feasibility and Safety of IMP321 (Eftilagimod Alpha) for Advanced Stage Solid Tumors
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
NCT07337525 RECRUITING A First in Human Study of PLT012 in Participants With Solid Tumor Cancers
Pilatus Biosciences Inc
NCT07197554 RECRUITING A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies
SEED Therapeutics, Inc.
NCT06524570 RECRUITING Treatment of Cancer With Immune Checkpoint Inhibition Therapy Boosted by High Intensity Focused Ultrasound Histotripsy
UMC Utrecht
NCT04485013 RECRUITING TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers
Tizona Therapeutics, Inc
NCT07066657 RECRUITING A Study of MRG007 (ARR-217) in Patients With Advanced Solid Tumors
ArriVent BioPharma, Inc.
NCT06885697 RECRUITING Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma
National Cancer Institute (NCI)
NCT06566079 RECRUITING Study of ISM6331 in Participants With Advanced/Metastatic Malignant Mesothelioma or Other Solid Tumors
InSilico Medicine Hong Kong Limited
NCT04928677 RECRUITING A Study of Codrituzumab in Children and Young Adults With Solid Tumors and Have Not Responded to Treatment or Have Come Back After Treatment
Memorial Sloan Kettering Cancer Center
NCT07123103 RECRUITING A Study of XB371 Administered in Participants With Locally Advanced or Metastatic Solid Tumors
Exelixis
NCT07148050 RECRUITING Immunotherapy for Solid Tumor Malignancies in Pediatrics Using Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor T Cells
Seattle Children's Hospital
NCT07238075 RECRUITING ADCX-020 for the Treatment of Patients With Locally Advanced or Metastatic Cancers
Adcytherix SAS
NCT04973163 ACTIVE NOT RECRUITING A Study to Test Different Doses of BI 1823911 Alone and Combined With Other Medicines in People With Different Types of Advanced Cancer With KRAS Mutation
Boehringer Ingelheim
NCT06778863 RECRUITING A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation
Clasp Therapeutics, Inc.
NCT05103683 RECRUITING First in Human Study of TORL-1-23 in Participants With Advanced Cancer
TORL Biotherapeutics, LLC
NCT06973863 RECRUITING A Study of PEP08 in Patients With MTAP-Del Advanced or Metastatic Solid Tumors
PharmaEngine
NCT07094113 RECRUITING AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors
Amgen
NCT06943677 RECRUITING A Clinical Trial on the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of TQB3019 Capsule in Subjects With Advanced Malignant Tumors
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT07329894 RECRUITING Safety, Tolerance and Preliminary Efficacy of XH001 Injection Combined With Neoantigen Vaccine-induced Tumor-specific T-cell Injection in Advanced Gastrointestinal Cancer
Beijing GoBroad Hospital
NCT07407985 ACTIVE NOT RECRUITING A Clinical Study to Evaluate GK01 Cell Injection in Combination With PD-1 Monoclonal Antibody for Advanced Solid Tumors
Tianjin Medical University Cancer Institute and Hospital
NCT07407504 NOT YET RECRUITING GenSci145 as Monotherapy or in Combination Therapy, in Participants With PIK3CA-mutated, Locally Advanced or Metastatic Solid Tumors.
Changchun GeneScience Pharmaceutical Co., Ltd.
NCT04449874 ACTIVE NOT RECRUITING A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-6036 Alone or in Combination in Participants With Advanced or Metastatic Solid Tumors With a KRAS G12C Mutation
Genentech, Inc.
NCT07404332 NOT YET RECRUITING 5-Azacitidine Plus PD-1/PD-L1 Inhibitor With PD-1/PD-L1 Refractory Tumors
Mohammed Milhem
NCT04617522 RECRUITING Study of Sacituzumab Govitecan in Participants With Advanced or Metastatic Solid Tumor and Moderate Liver Impairment
Gilead Sciences
NCT06440005 RECRUITING A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors
Angiex, Inc.
NCT07252479 RECRUITING Evaluation of RAS Inhibitor Treatment in Participants With Advanced or Metastatic Solid Tumors Harboring RAS Mutations
Adlai Nortye Biopharma Co., Ltd.
NCT06623396 RECRUITING A Study of Mesothelin-Targeted CAR T-Cell Therapy in People With Esophagogastric Cancer
Memorial Sloan Kettering Cancer Center
NCT07036133 RECRUITING Study to Evaluate the Pharmacokinetics and Safety of Pralatrexate in Patients With Advanced Solid Tumor or Hematological Malignancy and Either Normal Hepatic Function or Mild, Moderate, or Severe Hepatic Impairment
Acrotech Biopharma Inc.
NCT06750185 RECRUITING Safety and Preliminary Effectiveness of BNT317, an Investigational Therapy for Advanced Solid Tumors
BioNTech SE
NCT05947474 ACTIVE NOT RECRUITING ORB-011 In Patients With Advanced Solid Tumors
Orionis Biosciences Inc
NCT05082259 RECRUITING ASTEROID: A Trial of ASTX660 in Combination With Pembrolizumab
Institute of Cancer Research, United Kingdom
NCT06607939 RECRUITING ORB-021 In Patients With Advanced Solid Tumors
Orionis Biosciences Inc
NCT05787587 RECRUITING A Study of PARG Inhibitor IDE161 in Participants With Advanced Solid Tumors
IDEAYA Biosciences
NCT07080242 RECRUITING Evaluating BL-M14D1 in Subjects With Locally Advanced or Metastatic Small Cell Lung Cancer and Neuroendocrine Tumors
SystImmune Inc.
NCT05239143 ACTIVE NOT RECRUITING P-MUC1C-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Advanced or Metastatic Solid Tumors
Poseida Therapeutics, Inc.
NCT05479812 ACTIVE NOT RECRUITING Dose Escalation and Expansion Study of WTX-124 as Monotherapy and in Combination With Pembrolizumab (Pembro) in Patients With Selected Advanced or Metastatic Solid Tumors
Werewolf Therapeutics, Inc.
NCT05620017 RECRUITING Evaluate the Safety, Tolerability and Pharmacokinetic Characteristics of BAT8008 for Injection
Bio-Thera Solutions
NCT03740256 RECRUITING Binary Oncolytic Adenovirus in Combination With HER2-Specific Autologous CAR VST, Advanced HER2 Positive Solid Tumors
Baylor College of Medicine
NCT07391644 NOT YET RECRUITING A Study of JSKN027 in Patients With Advanced Solid Tumors
Jiangsu Alphamab Biopharmaceuticals Co., Ltd
NCT06507306 RECRUITING A Study to Investigate the Safety and Efficacy of KQB198 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies
Kumquat Biosciences Inc.
NCT06650163 RECRUITING Zr-89 Crefmirlimab Berdoxam and Immuno-Positron Emission Tomography for the Imaging of Patients With Resectable Brain Tumors
Jonsson Comprehensive Cancer Center
NCT06242470 RECRUITING A Study of MGC026 in Participants With Advanced Solid Tumors
MacroGenics
NCT07390539 NOT YET RECRUITING B7-H3.CD28Z.CART in CNS Neoplasms
Robbie Majzner
NCT06655246 RECRUITING A Study of Ziftomenib in Combination With Imatinib in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)
Kura Oncology, Inc.
NCT04459273 ACTIVE NOT RECRUITING Prospective Exploratory Study of FAPi PET/CT With Histopathology Validation in Patients With Various Cancers
Jonsson Comprehensive Cancer Center
NCT06880549 ACTIVE NOT RECRUITING A Study of mRNA-4106 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Solid Tumors
ModernaTX, Inc.
NCT07390838 RECRUITING A Study of SH009 Injection in Patients With Advanced Solid Tumors.
Nanjing Sanhome Pharmaceutical, Co., Ltd.
NCT03120624 ACTIVE NOT RECRUITING VSV-hIFNbeta-NIS With or Without Ruxolitinib Phosphate in Treating Stage IV or Recurrent Endometrial Cancer
Mayo Clinic
NCT07349537 RECRUITING Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors
Revolution Medicines, Inc.
NCT07292818 RECRUITING Hyaluronic Acid-based Gel Spacers in Gynecologic Malignancies
UNC Lineberger Comprehensive Cancer Center
NCT05892718 RECRUITING A Safety and Efficacy Study of HCB101, Fc-fusion Protein Targeting SIRPα-CD47 Pathway, in Solid or Hematological Tumors
FBD Biologics Limited
NCT06244485 RECRUITING A Study of Valemetostat Tosylate in Combination With DXd ADCs in Subjects With Solid Tumors
Daiichi Sankyo
NCT05352750 ACTIVE NOT RECRUITING Phase 1 Study of SON-1010 in Adult Patients With Advanced Solid Tumors
Sonnet BioTherapeutics
NCT06469281 RECRUITING A Study to Learn if 27T51, a Mucin-16 (MUC16) Protein Targeting Immune Cell Therapy, Administered Alone or in Combination is Safe and How Well it Works for Adult Participants With Recurrent or Treatment Resistant Ovarian Cancers
Regeneron Pharmaceuticals
NCT07381829 RECRUITING A Phase Ib Clinical Study on the Safety and Efficacy of HC010 Combined With Chemotherapy in Lung Cancer
HC Biopharma Inc.
NCT07215637 RECRUITING Phase Ia/Ib Study of CKD-512 Alone and in Combination With Pembrolizumab in Subjects With Advanced or Metastatic Solid Tumors
Chong Kun Dang Pharmaceutical
NCT06911489 RECRUITING Safety Trial of 68Ga/177Lu-NRT6020 in FAP-Positive Advanced Solid Tumor Patients
Chengdu New Radiomedicine Technology Co. LTD.
NCT06364696 ACTIVE NOT RECRUITING A Study to Find a Suitable Dose of ASP4396 in Adults With Solid Tumors
Astellas Pharma Inc
NCT05791448 RECRUITING AU409 for the Treatment of Advanced Primary Liver Cancers or Solid Tumor With Liver Metastatic Disease
University of Southern California
NCT06717750 RECRUITING A Study of CSCJC3456 in Patients With Advanced Malignant Tumors
Changshan ConjuChem BioPharmaceutical Research and Development (Hebei) Co., Ltd.
NCT04389281 RECRUITING X-ray Psoralen Activated Cancer Therapy in Head and Neck, Breast, Sarcoma and Melanoma
Immunolight, LLC
NCT06809114 RECRUITING FIH Study to Evaluate Safety, Tolerability, PK, PD & Preliminary Efficacy of AT03-65 With Advanced Solid Tumors
Axcynsis Therapeutics Pte Ltd
NCT07377591 RECRUITING A Study of HDM2006 in Patients With Advanced Solid Tumor
Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.
NCT04391049 ACTIVE NOT RECRUITING Testing the Addition of the Anti-cancer Viral Therapy Telomelysin™ to Chemoradiation for Patients With Advanced Esophageal Cancer and Are Not Candidates for Surgery
NRG Oncology
NCT04150042 RECRUITING SHARON: A Clinical Trial for Metastatic Cancer Using Chemotherapy and Patients' Own Stem Cells
General Oncology, Inc.
NCT06644300 RECRUITING Study of BM230 in Patients With Advanced Solid Tumors
Suzhou Biomissile Pharmaceuticals Co., Ltd.
NCT05983432 RECRUITING Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors
SystImmune Inc.
NCT06792552 RECRUITING A Phase I Study of SIM0505 in Participants With Advanced Solid Tumors
NextCure, Inc.
NCT05840224 ACTIVE NOT RECRUITING Study of GS-4528 in Adults With Solid Tumors
Gilead Sciences
NCT06993116 ACTIVE NOT RECRUITING A Phase I Study of SHR-4712 in Patients With Advanced Solid Tumors
Guangdong Hengrui Pharmaceutical Co., Ltd
NCT06484985 RECRUITING Study of AXT-1003 in Subjects With Advanced Malignant Tumors.
Axter Therapeutics (Beijing) Co., Ltd
NCT07269145 RECRUITING A Phase I Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of TQB3122 Capsules in Subjects With Advanced Malignant Tumors
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT06266299 RECRUITING A Study of KK2269 in Adult Participants With Solid Tumors
Kyowa Kirin Co., Ltd.
NCT06287918 NOT YET RECRUITING A First-in-human Study of 3HP-2827 in Patients With Unresectable or Metastatic Solid Tumors With FGFR2 Alterations
3H (Suzhou) Pharmaceuticals Co., Ltd.
NCT07368127 NOT YET RECRUITING A Study of TPD3310 in Patients With Advanced Malignant Tumors
TAIBIDI PHARMACEUTICAL TECHNOLOGY(SHIJIAZHUANG) CO.,LTD.
NCT02057133 ACTIVE NOT RECRUITING A Study of LY2835219 (Abemaciclib) in Combination With Therapies for Breast Cancer That Has Spread
Eli Lilly and Company
NCT05174637 ACTIVE NOT RECRUITING A Study of FDA018-ADC in Patients With Advanced Solid Tumors
Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd.
NCT06771219 RECRUITING SLV-154 Treatment of Metastatic Solid Tumors
Solve Therapeutics
NCT05827614 ACTIVE NOT RECRUITING Study of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), and the RNR Inhibitor BBI-825, in Subjects With Tumors With Oncogene Amplifications
Boundless Bio, Inc.
NCT06821048 RECRUITING Study of CEA Targeting CAR-T (PTC13) in the Treatment of CEA-Positive Advanced Malignant Solid Tumors
Weijia Fang, MD
NCT07363967 RECRUITING A Phase I First-in-Human Open-Label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Anti-Tumor Activity of SWA1211 Tablets in Subjects With Advanced Solid Tumors
Beijing StoneWise Technology Co., Ltd
NCT07363369 NOT YET RECRUITING Exploratory Clinical Study of FAP mRNA Vaccine in Patients With Advanced Malignant Solid Tumors
West China Hospital
NCT06150183 ACTIVE NOT RECRUITING Safety and Preliminary Efficacy of BNT314 in Cancer Patients With Malignant Solid Tumors
BioNTech SE
NCT07358806 RECRUITING Study to Assess the Effect of OCT-598 in Patients With Advanced Solid Tumors
Oscotec Inc.
NCT07042100 RECRUITING A Study to Test the Safety and Tolerability of SBO-154 in Patients With Advanced Solid Tumors.
Sun Pharma Advanced Research Company Limited
NCT07358884 NOT YET RECRUITING First in Human Study of QLS5316 in Solid Tumors
Qilu Pharmaceutical Co., Ltd.
NCT05653869 ACTIVE NOT RECRUITING A Study of APS03118 in Advanced Solid Tumors Harboring RET Mutations or Fusions
Applied Pharmaceutical Science, Inc.
NCT07358260 NOT YET RECRUITING B7-H3.CD28Z.CART in Solid Tumors
Robbie Majzner
NCT07361107 RECRUITING Evaluation of Circulating Immune Response After Histosonics in Colorectal Cancer (ECHO-CRC)
Northwell Health
NCT05914545 RECRUITING A Study of FZ-AD004 in Patients With Advanced Solid Tumors
Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd.
NCT07348653 NOT YET RECRUITING A Study of MG2512 Injection in Participants With Advanced Solid Tumors
Shanghai Mabgen Biopharmaceutical Technology Co., Ltd.
NCT07356856 NOT YET RECRUITING Efficacy and Safety of Microtransplantation for Advanced and Relapsed Solid Tumors
The Affiliated Hospital of the Chinese Academy of Military Medical Sciences
NCT06609187 RECRUITING A Study of GNC-077 in Patients With Locally Advanced or Metastatic Breast Cancer and Other Solid Tumors
Sichuan Baili Pharmaceutical Co., Ltd.
NCT07356453 RECRUITING A Study of PARG Inhibitor FORX-428 in Patients With Advanced Solid Tumors.
FoRx Therapeutics AG
NCT06612840 RECRUITING A Study of GNC-077 in Patients With Locally Advanced or Metastatic Non-small-cell Lung Cancer and Other Solid Tumors
Sichuan Baili Pharmaceutical Co., Ltd.
NCT06503783 RECRUITING A Study of BL-M17D1 in Patients With Locally Advanced or Metastatic HER2 Positive/Negative Breast Cancer and Other Solid Tumors
Sichuan Baili Pharmaceutical Co., Ltd.
NCT07317505 RECRUITING A Phase 1 Study of JMT108 in Participants With Advanced Solid Tumors
Conjupro Biotherapeutics, Inc.
NCT05519449 RECRUITING Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)
Janux Therapeutics
NCT07351903 RECRUITING A Single-arm, Open-label Study of GK01 in Combination With or Without Chemotherapy for the Adjuvant Treatment of Solid Tumors
Tianjin Medical University Cancer Institute and Hospital
NCT06736379 RECRUITING Intratumoral Delivery of Viral Replicon (saRNA) Particles Expressing IL-12 in Head and Neck Cancer
VLP Therapeutics
NCT06932952 ACTIVE NOT RECRUITING A Dose Escalation and Expansion Trial With BYON4228 Alone and in Combination in Patients With Advanced or Metastatic Solid Tumors
Byondis B.V.
NCT07186452 RECRUITING Evaluation of the Effect of Itraconazole on the Pharmacokinetics of HS-20093 in Patients With Advanced Solid Tumors
Hansoh BioMedical R&D Company
NCT01087554 ACTIVE NOT RECRUITING Sirolimus or Everolimus or Temsirolimus and Vorinostat in Advanced Cancer
M.D. Anderson Cancer Center
NCT07231458 RECRUITING A Study to Test a New Immunotherapy, ABX-001, Alone and in Combination With the Marketed Drug, Pembrolizumab, for the Treatment of Tumors Previously Treated With Other Therapies
Abalos Therapeutics GmbH
NCT06927570 RECRUITING A Study of HS-20122 in Patients With Advanced Solid Tumors
Hansoh BioMedical R&D Company
NCT07345637 NOT YET RECRUITING Phase I Study of FXS887 in the Treatment of Solid Tumors
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.
NCT07294872 NOT YET RECRUITING A Study of TIL in Advanced Solid Tumors (CZ)
Shanghai Juncell Therapeutics
NCT06302426 RECRUITING Trial of INI-4001 in Patients With Advanced Solid Tumours
Inimmune Corporation
NCT06751329 RECRUITING A Study of DM002 in Patients With Advanced Solid Tumors
Xadcera Biopharmaceutical (Suzhou) Co., Ltd.
NCT07275242 RECRUITING A Clinical Study of SHR-A1811(sc) Subcutaneous Injection in Patients With Solid Tumor
Suzhou Suncadia Biopharmaceuticals Co., Ltd.
NCT06302621 RECRUITING Pemigatinib + Afatinib in Advanced Refractory Solid Tumors
Massachusetts General Hospital
NCT06234423 RECRUITING A Study of CUSP06 in Patients With Platinum-Refractory/Resistant Ovarian Cancer and Other Advanced Solid Tumors
OnCusp Therapeutics, Inc.
NCT06859762 RECRUITING A First-in-Human Study of YL217 in Patients With Advanced Solid Tumors
MediLink Therapeutics (Suzhou) Co., Ltd.
NCT06400472 RECRUITING A Study of LY4170156 in Participants With Selected Advanced Solid Tumors
Eli Lilly and Company
NCT05092373 RECRUITING Phase I Study of Tumor Treating Fields (TTF) in Combination With Cabozantinib or With Pembrolizumab and Nab-Paclitaxel in Patients With Advanced Solid Tumors Involving the Abdomen or Thorax
M.D. Anderson Cancer Center
NCT04471987 RECRUITING Safety and Early Signs of Efficacy of IL12-L19L19.
Philogen S.p.A.
NCT02715284 ACTIVE NOT RECRUITING Study of TSR-042, an Anti-programmed Cell Death-1 Receptor (PD-1) Monoclonal Antibody, in Participants With Advanced Solid Tumors
Tesaro, Inc.
NCT05156866 ACTIVE NOT RECRUITING First in Human Study of TORL-2-307-ADC in Participants With Advanced Cancer
TORL Biotherapeutics, LLC
NCT07197645 RECRUITING Samarium Optimized for Long-lasting Analgesia in Cancerous End-stage Bone Pain
Telix Pharmaceuticals (Innovations) Pty Limited
NCT06466187 ACTIVE NOT RECRUITING A Study of SGN-MesoC2 in Advanced Solid Tumors
Seagen, a wholly owned subsidiary of Pfizer
NCT07181473 RECRUITING A Study to Evaluate the Safety, Pharmacokinetics and Efficacy of TJ101 in Patients With Advanced/Metastatic Solid Tumors
Phrontline Biopharma
NCT03875287 ACTIVE NOT RECRUITING Dose-Escalation Study of E7727, an Oral Cytidine Deaminase Inhibitor With Oral Decitabine in Subjects With Solid Tumors
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT07333820 NOT YET RECRUITING Clinical Study to Evaluate the Safety and Anti-Tumor Activity of AB-201
Yonsei University
NCT07312903 RECRUITING DPTX3186 in Wnt Pathway Activated Solid Tumors
Dewpoint Therapeutics
NCT06816108 RECRUITING A Study of ONO-7428 in Participants With Unresectable Advanced or Recurrent Solid Tumors
Ono Pharmaceutical Co., Ltd.
NCT04111458 ACTIVE NOT RECRUITING A Study to Test Different Doses of BI 1701963 Alone and Combined With Trametinib in Patients With Different Types of Advanced Cancer (Solid Tumours With KRAS Mutation)
Boehringer Ingelheim
NCT02988960 ACTIVE NOT RECRUITING A Study of ABBV-927 and ABBV-181, an Immunotherapy, in Participants With Advanced Solid Tumors
AbbVie
NCT04673448 ACTIVE NOT RECRUITING Niraparib and TSR-042 for the Treatment of BRCA-Mutated Unresectable or Metastatic Breast, Pancreas, Ovary, Fallopian Tube, or Primary Peritoneal Cancer
University of Washington
NCT06856499 RECRUITING Cirtuvivint/Olaparib in Breast Cancer Susceptibility Gene/Homologous Recombination Deficiency Platinum Resistant Ovarian Cancer
University of Colorado, Denver
NCT05902520 ACTIVE NOT RECRUITING Adoptive Cell Therapy Using Cancer Specific CD8+ Tumor Infiltrating Lymphocytes in Adult Patients With Solid Tumors
AgonOx, Inc.
NCT07131189 ACTIVE NOT RECRUITING A Study of FL115 Monotherapy in Unresectable or Metastatic Solid Tumors
Suzhou Forlong Biotechnology Co., Ltd
NCT03843359 ACTIVE NOT RECRUITING A First Time in Human (FTIH) Study of GSK3745417 Administered to Participants With Advanced Solid Tumors
GlaxoSmithKline
NCT06990464 RECRUITING A Clinical Trial of SIBP-A19 Injection in the Treatment of Advanced Malignant Solid Tumor Patients
Shanghai Institute Of Biological Products
NCT05614258 ACTIVE NOT RECRUITING Study of ADG206 in Subjects With Advanced/Metastatic Solid Tumors
Adagene Inc
NCT06235437 RECRUITING Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ASD141
Ascendo Biotechnology Co., Ltd.
NCT06985368 RECRUITING A Clinical Trial of SIBP-A18 Injection in the Treatment of Advanced Malignant Solid Tumor Patients
Shanghai Institute Of Biological Products
NCT06781983 RECRUITING Safety and Tolerability of IPH4502 in Patients With Advanced Solid Tumors
Innate Pharma
NCT06999187 RECRUITING A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas
Dren Bio
NCT06298058 RECRUITING A Clinical Trial of SIBP-A13 Injection in the Treatment of Advanced Malignant Solid Tumor Patients.
Shanghai Institute Of Biological Products
NCT07277270 RECRUITING A Study of GSK5764227 in Combination With Standard of Care (SoC) or Other Agents in Participants With Advanced Solid Tumors
GlaxoSmithKline
NCT07232407 RECRUITING A Study of Lutetium [177Lu] BL-ARC001 in Patients With Locally Advanced or Metastatic Gastrointestinal Tumors and Other Solid Tumors
Sichuan Baili Pharmaceutical Co., Ltd.
NCT06512116 RECRUITING A Clinical Trial of SIBP-A17 Injection in the Treatment of Advanced Solid Tumor Patients.
Shanghai Institute Of Biological Products
NCT07319364 RECRUITING A Real-World Study of Fecal Transplants for Cancer Therapy Side Effects
Second Affiliated Hospital, School of Medicine, Zhejiang University
NCT03602157 ACTIVE NOT RECRUITING Study of CAR-T Cells Expressing CD30 and CCR4 for r/r CD30+ HL and CTCL
UNC Lineberger Comprehensive Cancer Center
NCT07274852 RECRUITING A Study of Lutetium [177Lu]-BL-ARC001 in Patients With Locally Advanced or Metastatic Lung Cancer, Breast Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors
Sichuan Baili Pharmaceutical Co., Ltd.
NCT03955978 ACTIVE NOT RECRUITING TSR-042 in Addition to Standard of Care Definitive Radiation for Inoperable Endometrial Cancer
Washington University School of Medicine
NCT05544929 ACTIVE NOT RECRUITING A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced Cancers
Novartis Pharmaceuticals
NCT03912064 ACTIVE NOT RECRUITING A Phase 1 Trial of CD25/Treg-depleted DLI Plus Ipilimumab for Myeloid Disease Relapse After Matched-HCT
Dana-Farber Cancer Institute
NCT07077434 RECRUITING A Study to Assess Safety, Tolerability and Drug Levels of BMS-986504 in Participants With Advanced Solid Tumors
Bristol-Myers Squibb
NCT07252414 RECRUITING GenSci143 in Participants With Advanced Solid Tumors
Changchun GeneScience Pharmaceutical Co., Ltd.
NCT06384352 RECRUITING A Phase I Study to Evaluate the Safety,Tolerability, Pharmacokinetics, and Efficacy of YL211 in Patients With Advanced Solid Tumors
MediLink Therapeutics (Suzhou) Co., Ltd.
NCT07310134 RECRUITING Study to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of ZX-8177 in Patients With Advanced Solid Tumors
Nanjing Zenshine Pharmaceuticals
NCT06724926 ACTIVE NOT RECRUITING Concurrent Azeliragon With Craniospinal Irradiation
NYU Langone Health
NCT07232524 RECRUITING A Study of BL-M24D1 in Patients With Locally Advanced or Metastatic Head and Neck Squamous Cell Carcinoma and Other Solid Tumors
Sichuan Baili Pharmaceutical Co., Ltd.
NCT06350006 RECRUITING SHR-A1904 Combinations in CLDN18.2-Positive Advanced Solid Tumor
Shanghai Hengrui Pharmaceutical Co., Ltd.
NCT02208375 ACTIVE NOT RECRUITING mTORC1/2 Inhibitor AZD2014 or the Oral AKT Inhibitor AZD5363 for Recurrent Endometrial and Ovarian
M.D. Anderson Cancer Center
NCT04621435 RECRUITING Imaging of Solid Tumors Using FAP-2286
Thomas Hope
NCT06368921 RECRUITING A Study of Recombinant Oncolytic Virus M1(VRT106) in Patients With Solid Tumors
Guangzhou Virotech Pharmaceutical Co., Ltd.
NCT06908434 RECRUITING A Phase I First-in-Human Study of GenSci128 in Patients With Solid Tumors Harboring a TP53 Y220C Mutation
Changchun GeneScience Pharmaceutical Co., Ltd.
NCT05957081 RECRUITING Study to Assess the Safety, Tolerability, and Blood Concentration of PMC-309
PharmAbcine
NCT05007782 RECRUITING Study of Denikitug (GS-1811) Given Alone or With Zimberelimab in Adults With Advanced Solid Tumors
Gilead Sciences
NCT06882135 RECRUITING HW071021 Monotherapy in Patients With Advanced Solid Tumors
Wuhan Humanwell Innovative Drug Research and Development Center Limited Company
NCT07100210 RECRUITING A Clinical Trial Evaluating IL-22BP/LNP Compound in Refractory Malignant Solid Tumors for Safety, Tolerability and Activity
Xingchen Peng
NCT05075993 ACTIVE NOT RECRUITING Study of LVGN3616 and LVGN6051±LVGN7409 in Combination With Nab-Paclitaxel or Bevacizumab and Cyclophosphamide in Metastatic Solid Tumors
M.D. Anderson Cancer Center
NCT06952010 RECRUITING A Study of XB628 in Participants With Recurrent Advanced or Metastatic Solid Tumors
Exelixis
NCT06022029 RECRUITING A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.
OncoNano Medicine, Inc.
NCT07251166 RECRUITING A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of GenSci140 in Participants With Advanced Solid Tumors
Changchun GeneScience Pharmaceutical Co., Ltd.
NCT07230977 RECRUITING GenSci139 in Patients With Advanced Solid Tumors
Changchun GeneScience Pharmaceutical Co., Ltd.
NCT06328673 ACTIVE NOT RECRUITING A Study of DM919 Alone and in Combination With Pembrolizumab in Advanced Solid Tumors
D2M Biotherapeutics Inc.
NCT07256756 NOT YET RECRUITING A Study of GC203 TIL in Advanced Solid Tumors (NF)
Shanghai Juncell Therapeutics
NCT04777994 RECRUITING Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors
Calico Life Sciences LLC
NCT05306132 RECRUITING Study to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Anti-tumor Activity of ASKC202 With or Without ASK120067
Jiangsu Aosaikang Pharmaceutical Co., Ltd.
NCT07292402 RECRUITING JSKN022 in Subjects With Advanced Malignant Solid Tumors
Jiangsu Alphamab Biopharmaceuticals Co., Ltd
NCT03423628 RECRUITING A Study to Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer
AstraZeneca
NCT06131398 ACTIVE NOT RECRUITING A Study of AMG 355 Alone and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors
Amgen
NCT07128914 RECRUITING A Clinical Study of GO306 in Patients With Advanced Solid Tumors
GeneSail Biotech (Shanghai) Co., Ltd.
NCT05270213 RECRUITING Evaluation of RBS2418 in Subjects With Advanced, Metastatic Solid Tumors
Riboscience, LLC.
NCT05802056 RECRUITING Aldesleukin With Nivolumab and Standard Chemotherapy for Treatment of Gastric Cancer With Peritoneal Metastasis
Mayo Clinic
NCT06065371 RECRUITING Sacituzumab Govitecan in Combination With Capecitabine for Advanced Gastrointestinal Cancers After Progression on Standard Therapy
Henry Ford Health System
NCT05276973 ACTIVE NOT RECRUITING Testing the Addition of Ipatasertib to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) for Stage III or IV Epithelial Ovarian Cancer
National Cancer Institute (NCI)
NCT06727812 RECRUITING Multicenter Phase I Study of HRS-6208 in Patients With Solid Tumors
Shandong Suncadia Medicine Co., Ltd.
NCT05836324 RECRUITING A Study to Evaluate the Safety of INCA33890 in Participants With Advanced or Metastatic Solid Tumors
Incyte Corporation
NCT06551142 RECRUITING A Study of GSK5764227 in Participants With. Advanced Solid Tumors (EMBOLD PanTumor-101)
GlaxoSmithKline
NCT07291050 NOT YET RECRUITING A Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of TQB3217 Tablets in Subjects With Advanced Malignant Tumors
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT04541082 RECRUITING Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms
Jazz Pharmaceuticals
NCT07275073 RECRUITING JMT106 Injection in the Treatment of Advanced Solid Tumors
Shanghai JMT-Bio Inc.
NCT06797336 RECRUITING A Study of PT0253 in Participants With KRAS G12D Mutated Advanced Solid Tumors
PAQ Therapeutics, Inc.
NCT07288957 RECRUITING A Early Study of ABSK131 in Patients With Advanced/Metastatic Solid Tumors
Abbisko Therapeutics Co, Ltd
NCT07266285 RECRUITING BTM-3566 in Advanced Solid Tumors
Bantam Pharmaceuticals
NCT06724016 RECRUITING Dose Escalation and Expansion Study of HM16390 Alone or With Pembrolizumab in Advanced or Metastatic Solid Tumors
Hanmi Pharmaceutical Company Limited
NCT05471856 RECRUITING A Study to Test How Different Doses of BI 1703880 in Combination With Ezabenlimab Are Tolerated in People With Different Types of Advanced Cancer (Solid Tumours)
Boehringer Ingelheim
NCT05856981 RECRUITING Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors
Sairopa B.V.
NCT07285395 RECRUITING AT1019 Plus SBRT and PD-1 Inhibitor for Advanced Solid Tumors: An IIT Study
The Affiliated Hospital of Xuzhou Medical University
NCT06774963 RECRUITING A Phase 1 Study of LNCB74 in Advanced Solid Tumors
NextCure, Inc.
NCT06108050 RECRUITING JZP898 Intravenous Infusion as Monotherapy and Combination With Pembrolizumab in Adults With Advanced/Metastatic Solid Tumors
Jazz Pharmaceuticals
NCT05159700 ACTIVE NOT RECRUITING A Phase I Study, Evaluating the Safety, Pharmacokinetics and Efficacy of PRJ1-3024 in Subjects With Advanced Solid Tumors
Zhuhai Yufan Biotechnologies Co., Ltd
NCT07281326 RECRUITING A Study of AK138D1 in Advanced Malignant Tumors
Akeso
NCT05539430 ACTIVE NOT RECRUITING Claudin 18.2-Targeted Chimeric Antigen Receptor T-cells in Subjects With Unresectable, Locally Advanced, or Metastatic Gastric, Gastroesophageal Junction (GEJ), Esophageal, or Pancreatic Adenocarcinoma
Legend Biotech USA Inc
NCT04898543 ACTIVE NOT RECRUITING QUILT-3.076: Study of Autologous M-CENK in Subjects With Locally Advanced or Metastatic Solid Tumors
ImmunityBio, Inc.
NCT06414460 RECRUITING Study of ISM3412 in Participants With Locally Advanced/Metastatic Solid Tumors
InSilico Medicine Hong Kong Limited
NCT06375187 RECRUITING A Study of GC203 TIL in Advanced Malignant Solid Tumors
Shanghai Juncell Therapeutics
NCT06724042 NOT YET RECRUITING Study of ISM5939 in Patients With Advanced and/or Metastatic Solid Tumors
InSilico Medicine Hong Kong Limited
NCT07275853 NOT YET RECRUITING Personalized KXV01 Lentinvivo (TCR) Injection as the Therapy for Advanced Solid Tumors
TCRx Therapeutics Co.Ltd
NCT07159126 RECRUITING A Study of DS3610a in Participants With Advanced Solid Tumor
Daiichi Sankyo
NCT07257640 RECRUITING IL-5 CAR-T Cell Therapy for Refractory/Relapsed Eosinophilic Leukemia
Zhejiang University
NCT07274085 RECRUITING A Phase 1 Study of HDM2017 in Advanced Solid Tumors
Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.
NCT04329494 RECRUITING PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer
City of Hope Medical Center
NCT06241456 RECRUITING FT825/ONO-8250, an Off-the-Shelf, HER2 CAR-T, With or Without Monoclonal Antibodies in Advanced Solid Tumors
Fate Therapeutics
NCT05338658 RECRUITING Study of PAT in Patients With Solid Tumor Cancers
Masonic Cancer Center, University of Minnesota
NCT07221058 RECRUITING Adaptive Radiation Boost for Rectal Cancer
Fox Chase Cancer Center
NCT07231120 RECRUITING A Phase I Clinical Study Evaluating the Safety, Tolerability, Pharmacokinetic Characteristics, and Preliminary Efficacy of SXRN Injection in Patients With Cancer Cachexia
Jiangsu Nutai Biologics Co., Ltd
NCT07269899 RECRUITING A Phase I Study of WTX212A Monotherapy or in Combination With Radiotherapy in Patients With Advanced Solid Tumors
Sun Yat-sen University
NCT06107868 ACTIVE NOT RECRUITING Phase 1 Study of RP-6306 With Carboplatin and Paclitaxel in TP53 Ovarian and Uterine Cancer
University Health Network, Toronto
NCT06115642 RECRUITING A Phase I Study to Evaluate the Safety, Tolerability, and PK of HLX43 in Advanced/Metastatic Solid Tumors
Shanghai Henlius Biotech
NCT03257761 ACTIVE NOT RECRUITING Guadecitabine and Durvalumab in Treating Patients With Advanced Liver, Pancreatic, Bile Duct, or Gallbladder Cancer
University of Southern California
NCT05245500 RECRUITING Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion
Bristol-Myers Squibb
NCT07134998 RECRUITING Phase I Study of HRS-6093 in Participants With Advanced Solid Tumors Harboring KRAS G12D Mutations
Jiangsu HengRui Medicine Co., Ltd.
NCT07265921 RECRUITING A Phase I Study of SIM0609 in Adult Participants With Locally Advanced/Metastatic Solid Tumors
Jiangsu Simcere Pharmaceutical Co., Ltd.
NCT05859074 RECRUITING A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancer
Memorial Sloan Kettering Cancer Center
NCT07260513 ACTIVE NOT RECRUITING A Phase 1 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of GH2616 in Subjects With Advanced Solid Tumor.
Suzhou Genhouse Bio Co., Ltd.
NCT07021898 RECRUITING A Study of ERAS-4001 in Patients With Advanced or Metastatic Solid Tumors.
Erasca, Inc.
NCT06299839 RECRUITING PAS-004 in Patients With Advanced Solid Tumors
Pasithea Therapeutics Corp.
NCT02869217 ACTIVE NOT RECRUITING Study of TBI-1301 (NY-ESO-1 Specific TCR Gene Transduced Autologous T Lymphocytes) in Patients With Solid Tumors
University Health Network, Toronto
NCT05013216 RECRUITING Mutant KRAS -Targeted Long Peptide Vaccine for Patients at High Risk of Developing Pancreatic Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT07260591 RECRUITING VSV-02 Compassionate Use in Advanced Solid Tumors
The First Affiliated Hospital of Xinxiang Medical College
NCT06912087 RECRUITING Dose Finding Study of Zanzalintinib With Pembrolizumab and Cetuximab in Head and Neck SCC
University of Chicago
NCT07259889 RECRUITING Safety and Tolerability Evaluation of CEL001 Injection in Advanced Solid Tumors
Guangzhou Xiling Biotechnology Co., Ltd.
NCT07257497 NOT YET RECRUITING Safety and Efficacy of Combining a Vitamin B6-Limited Diet With Immunotherapy in Solid Tumor Patients: A Clinical Study Protocol
West China Hospital
NCT07208136 RECRUITING A Study of JMKX005425 in Patients With MSI-H/dMMR Advanced Solid Tumors
Jemincare
NCT03983954 ACTIVE NOT RECRUITING Naptumomab Estafenatox in Combination With Durvalumab in Subjects With Selected Advanced or Metastatic Solid Tumor, Including a Cohort Expansion in Esophageal Cancer.
NeoTX Therapeutics Ltd.
NCT07252661 NOT YET RECRUITING Study of ACC-1898 in Adult Participants With Advanced Solid Tumors
AccSalus Biosciences, Inc.
NCT06215846 ENROLLING BY INVITATION A Clinical Study Evaluating the Safety and Efficacy of BioTTT001 in Patients With Malignant Solid Tumors
Beijing Bio-Targeting Therapeutics Technology Co., Ltd
NCT05547321 RECRUITING Efficacy and Safety Study of OMTX705, Monotherapy and Anti-PD-1-combined, in Subjects With Advanced Solid Tumors.
Oncomatryx Biopharma S.L.
NCT05901285 RECRUITING Phase 1 Study of Intratumoral Administration of VAX014 With Expansion in Combination With a Checkpoint Inhibitor in Subjects With Advanced Solid Tumors
Vaxiion Therapeutics
NCT06662760 RECRUITING Clinical Trial of TQB3002 in Patients With Advanced Cancers
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT07081984 RECRUITING Study of TI-0093 Injection With Recurrent/Metastatic HPV-16 Positive Solid Tumors
Therorna
NCT07106827 RECRUITING A Study of GV20-0251 in Advanced or Refractory Solid Tumors
West China Hospital
NCT05631899 ACTIVE NOT RECRUITING CAR-DC Vaccine and ICIs in Local Advanced/Metastatic Solid Tumors
Chinese PLA General Hospital
NCT05117476 ACTIVE NOT RECRUITING A Study of CLN-619 Alone and in Combination With Pembrolizumab in Advanced Solid Tumors
Cullinan Therapeutics Inc.
NCT07232420 RECRUITING A Study of BL-M24D1 in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer and Other Solid Tumors
Sichuan Baili Pharmaceutical Co., Ltd.
NCT06238401 RECRUITING An Open-label, Multi-center, Dose-escalation and Cohort Expansion Phase I/IIa Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetic Profile and Efficacy of ACR246 in Patients With Advanced Solid Tumors
Hangzhou Adcoris Biopharmacy Co., Ltd
NCT05743621 RECRUITING Study of TVB-2640 in Men With Metastatic Castration-Resistant Prostate Cancer
Weill Medical College of Cornell University
NCT06915753 RECRUITING Safety and Preliminary Anti-Tumor Activity of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors With Activating FGF/FGFR Pathway Aberrations
Tyra Biosciences, Inc
NCT03618381 ACTIVE NOT RECRUITING EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults
Seattle Children's Hospital
NCT05522868 RECRUITING SB17170 Phase 1 Clinical Trial in Solid Tumors
SPARK Biopharma
NCT07123415 RECRUITING A Phase 1 Study of APX-343A as Monotherapy or in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors
Aptabio Therapeutics, Inc.
NCT07237464 RECRUITING To Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of GB18 Injection in Healthy Participants
Shenzhen Kexing Pharmaceutical Co., Ltd.
NCT06328738 ACTIVE NOT RECRUITING ELVN-002 With Trastuzumab +/- Chemotherapy in HER2+ Solid Tumors, Colorectal and Breast Cancer
Enliven Therapeutics
NCT05608148 RECRUITING Clinical Trial of GAIA-102 for Refractory/Relapse Neuroblastomas and Other Malignant Pediatric Solid Tumors
Kyushu University
NCT06897735 NOT YET RECRUITING Exploratory Study of Inhaled Afatinib Dimaleate PK Profile
Petrov, Andrey
NCT04999384 RECRUITING First in Human, Dose Escalation Study of AN4005
Adlai Nortye Biopharma Co., Ltd.
NCT07229898 RECRUITING A Phase Ⅰ Clinical Study of GEN-725 Tablets in Patients With Advanced Solid Tumors
Henan Genuine Biotech Co., Ltd.
NCT06618651 RECRUITING A Study of SHR-3821 Injection in Subjects With Advanced Solid Tumors
Suzhou Suncadia Biopharmaceuticals Co., Ltd.
NCT06258408 RECRUITING A Phase 1 Study of BB102 in Participants With Advanced Solid Tumors
Broadenbio Ltd., Co.
NCT07142980 RECRUITING A Phase I Study of HRS-7172 in Participants With Advanced Solid Tumors Harboring RAS Mutations or Amplifications
Jiangsu HengRui Medicine Co., Ltd.
NCT05629689 RECRUITING A Study to Evaluate GEH200520/GEH200521 (18F) Safety and Tolerability When Used for PET Scans in Patients With Solid Tumour Malignancies
GE Healthcare
NCT06143007 ACTIVE NOT RECRUITING A Phase 1 Study of BB3008 in Participants With Advanced Solid Tumors
Broadenbio Ltd., Co.
NCT07231081 RECRUITING Phase I Study of TX103 CAR-T Cells in Participants With Advanced Solid Tumors
Tcelltech Inc.
NCT05661461 RECRUITING Dose-escalation Study to Assess Safety and Pharmacokinetics of Nab-Sirolimus in Patients With Locally Advanced or Metastatic Solid Tumors and Moderate Liver Impairment
Aadi Bioscience, Inc.
NCT03582475 ACTIVE NOT RECRUITING Pembrolizumab With Combination Chemotherapy in Treating Participants With Locally Advanced or Metastatic Small Cell/Neuroendocrine Cancers of Urothelium or Prostate
Jonsson Comprehensive Cancer Center
NCT03093909 RECRUITING Study of Aerosol Gemcitabine in Patients With Solid Tumors and Pulmonary Metastases
M.D. Anderson Cancer Center
NCT02321501 ACTIVE NOT RECRUITING Ceritinib and Everolimus in Treating Patients With Locally Advanced or Metastatic Solid Tumors or Stage IIIB-IV Non-small Cell Lung Cancer
M.D. Anderson Cancer Center
NCT07139990 RECRUITING Personalized Radiotherapy for Individualized Treatment Strategies and Monitoring (PRISM)
University of Texas Southwestern Medical Center
NCT06675136 RECRUITING Nab-Paclitaxel PIPAC in Combination With Paclitaxel and Ramucirumab for the Treatment of Stomach Cancer With Peritoneal Metastases
City of Hope Medical Center
NCT06006273 RECRUITING A Phase Ib Trial of Eribulin in Combination With Irinotecan and Temozolamide in Children With Relapsed or Refractory Solid Tumors
M.D. Anderson Cancer Center
NCT06504368 RECRUITING Safety, Tolerability, and Pharmacokinetics of DCR-PDL1 in Adults With Solid Tumors
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company
NCT07098299 RECRUITING Metformin Combined With Chemotherapy and/or Immunotherapy in Solid Malignancies
Barbara Ann Karmanos Cancer Institute
NCT06291987 RECRUITING Ivosidenib and Ruxolitinib in Patients With Advanced Myeloproliferative Neoplasms (MPNs) That Have an IDH1 Gene Mutation
University of Chicago
NCT07224568 NOT YET RECRUITING Cytokine Armored GPC3 Specific Chimeric Antigen Receptor Expressing T-cells in Adults With Solid Tumors
Seattle Children's Hospital
NCT06714617 ACTIVE NOT RECRUITING Evaluate BL-M17D1 in Patients w/HER2-Expressing/Mutant Advanced or Metastatic Solid Tumors
SystImmune Inc.
NCT05880667 RECRUITING Adaptive Radiation for Abdominopelvic Metastases
Fox Chase Cancer Center
NCT05274048 RECRUITING Neratinib and Fam-Trastuzumab Deruxtecan in Advanced Gastro-esophageal Cancer Patients
Fox Chase Cancer Center
NCT03484299 RECRUITING Chemotherapy and Irreversible Electroporation in the Treatment of Advanced Pancreatic Adenocarcinoma
University of Louisville
NCT05029882 ACTIVE NOT RECRUITING Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Advanced Solid Tumors Receiving Intravenous (IV) ABBV-400 as Monotherapy and in Combination With IV Bevacizumab
AbbVie
NCT05327946 ACTIVE NOT RECRUITING A Study in People With Advanced Cancer to Test How Well Different Doses of BI 770371 Alone or in Combination With Ezabenlimab Are Tolerated
Boehringer Ingelheim
NCT02817633 ACTIVE NOT RECRUITING A Study of TSR-022 in Participants With Advanced Solid Tumors (AMBER)
Tesaro, Inc.
NCT04446351 ACTIVE NOT RECRUITING Study of the Safety and Effectiveness of GSK6097608 in Participants With Advanced Solid Tumors
GlaxoSmithKline
NCT04169763 RECRUITING Nelfinavir, Cisplatin, and External Beam Radiation Therapy for the Treatment of Locally Advanced Vulvar Cancer That Cannot Be Removed by Surgery
M.D. Anderson Cancer Center
NCT04185883 ACTIVE NOT RECRUITING Sotorasib Activity in Subjects With Advanced Solid Tumors With KRAS p.G12C Mutation (CodeBreak 101)
Amgen
NCT03889795 ACTIVE NOT RECRUITING Phase IB Metformin, Digoxin, Simvastatin in Solid Tumors
Danae Hamouda, MD
NCT05627063 ACTIVE NOT RECRUITING A Study to Assess Safety, Tolerability, and Pharmacokinetics of ABSK121-NX in Patients With Advanced Solid Tumors
Abbisko Therapeutics Co, Ltd
NCT01514552 ACTIVE NOT RECRUITING The Use of Functional Confections in Promoting Oral Health
Ohio State University
NCT06084416 ACTIVE NOT RECRUITING A Study of Sovilnesib in Subjects With Ovarian Cancer
Volastra Therapeutics, Inc.
NCT07216833 NOT YET RECRUITING Decitabine and Nivolumab in Participants With Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck
Kyunghee Burkitt, DO, PhD
NCT05948826 ACTIVE NOT RECRUITING First in Human Study of TORL-3-600 in Participants With Advanced Cancer
TORL Biotherapeutics, LLC
NCT06752681 RECRUITING To Evaluate the Safety, Tolerability, Pharmacokinetics and Antitumor Activity of DAY301 in Participants With Locally Advanced or Metastatic Solid Tumors
Day One Biopharmaceuticals, Inc.
NCT04058756 ACTIVE NOT RECRUITING Rollover Study for Continued Safety and Tolerability in Subjects Treated With Spartalizumab Alone or in Combination With Other Study Treatments
Novartis Pharmaceuticals
NCT07207681 NOT YET RECRUITING Personalized KXV01 TCR Lentinvivo Injection as the Therapy for Advanced Solid Tumors
The First Hospital of Jilin University
NCT06990698 RECRUITING A Phase 1 Study to Investigate FP008 in Subjects With Advanced Solid Tumors
Zhuhai Fapon Biopharma Co., Ltd.
NCT07179692 RECRUITING CEA-Targeted CAR-T Therapy in CEA-Positive Advanced Solid Tumors
Chongqing Precision Biotech Co., Ltd
NCT04887935 RECRUITING Neoadjuvant SGLT2 Inhibition in Localized Prostate Cancer
Washington University School of Medicine
NCT03993873 ACTIVE NOT RECRUITING Study of TPX-0022 in Patients With Advanced NSCLC, Gastric Cancer or Solid Tumors Harboring Genetic Alterations in MET
Turning Point Therapeutics, Inc.
NCT06933524 NOT YET RECRUITING Evaluation of Safety and Tolerability of ATB-320 in Participants With Progressive or Metastatic Solid Tumors
Autotelicbio
NCT07200479 NOT YET RECRUITING A Clinical Study to Explore CT1194D in Patients With Relapsed/Refractory B-Cell Neoplasms
Institute of Hematology & Blood Diseases Hospital, China
NCT06126666 RECRUITING A Study With ABL103 in Subjects With Advanced or Metastatic Solid Tumors
ABL Bio, Inc.
NCT06136884 RECRUITING A First-In-Human, Phase 1 Study Evaluating Oral TACC3 PPI Inhibitor, AO-252, in Advanced Solid Tumors With or Without Brain Metastases
A2A Pharmaceuticals Inc.
NCT04295863 RECRUITING Comparing Dosing Intervals of Nivolumab or Pembrolizumab in Locally Advanced or Metastatic Cancers
University of Chicago
NCT05423977 ENROLLING BY INVITATION Study of ZV0203 in Patients With HER2-Positive Advanced Solid Tumors
Hangzhou Adcoris Biopharmacy Co., Ltd
NCT06088472 RECRUITING TIL Injection for the Treatment of Metastatic or Recurrent Solid Tumors
Grit Biotechnology
NCT07196579 NOT YET RECRUITING Personalized KXV01 TCR Lentinvivo Injection as the Therapy for Advanced Solid Tumors
TCRx Therapeutics Co.Ltd
NCT04794972 RECRUITING A Study of GNC-039, a Tetra-specific Antibody, in Participants With Relapsed/Refractory or Metastatic Solid Tumors
Sichuan Baili Pharmaceutical Co., Ltd.
NCT05470348 RECRUITING A Study of BL-B01D1 in Patients With Unresectable Locally Advanced or Metastatic Breast Cancer and Other Solid Tumors
Sichuan Baili Pharmaceutical Co., Ltd.
NCT05393427 ACTIVE NOT RECRUITING A Study of BL-B01D1 in Patients With Locally Advanced or Metastatic Urological Tumors and Other Solid Tumors
Sichuan Baili Pharmaceutical Co., Ltd.
NCT05631964 RECRUITING Phase I Clinical Study of BL-M07D1 in Locally Advanced or Metastatic Digestive Tract Tumors and Other Solid Tumors
Sichuan Baili Pharmaceutical Co., Ltd.
NCT05385692 ACTIVE NOT RECRUITING A Study of BL-M02D1 in Patients With Locally Advanced or Metastatic Gastrointestinal Tumors or Other Solid Tumors
Sichuan Baili Pharmaceutical Co., Ltd.
NCT06241898 RECRUITING A First-in-human of Multiplle Doses of BB-1709 in Subjects With Locally Advanced/Metastatic Solid Tumors
Bliss Biopharmaceutical (Hangzhou) Co., Ltd
NCT04606472 ACTIVE NOT RECRUITING A Study of SI-B003, a PD-1/CTLA-4 Bispecific Antibody, in Patients With Advanced Solid Tumors
Sichuan Baili Pharmaceutical Co., Ltd.
NCT05194982 RECRUITING A Study of BL-B01D1 in Patients With Locally Advanced or Metastatic Solid Tumor
Sichuan Baili Pharmaceutical Co., Ltd.
NCT05461768 RECRUITING A Study of BL-M07D1 in Patients With Locally Advanced or Metastatic HER2 Positive/Low Expression Breast Cancer and Other Solid Tumors
Sichuan Baili Pharmaceutical Co., Ltd.
NCT06953453 RECRUITING A Study of Inhaled Fentanyl Aerosol in Chinese Patients With Malignant Tumors
Lee's Pharmaceutical Limited
NCT03191682 ACTIVE NOT RECRUITING A First-in-Human Study of PRL3-ZUMAB
National University Hospital, Singapore
NCT05841563 RECRUITING Clinical Trial of PM54 in Advanced Solid Tumors Patients.
PharmaMar
NCT05485974 ACTIVE NOT RECRUITING A Dose Escalation Study of HBI-2438 in Patients With Solid Tumors Harboring KRAS G12C Mutation
HUYABIO International, LLC.
NCT05163028 ACTIVE NOT RECRUITING A Dose Escalation Study of SHP2 Inhibitor in Patients With Solid Tumors Harboring KRAS of EGFR Mutations
HUYABIO International, LLC.
NCT06674538 ENROLLING BY INVITATION Clinical Trial to Treat Stage IV Cancer Patients
Moonshot Antibodies
NCT06210815 RECRUITING A Study of HLX42 in Advanced/Metastatic Solid Tumors
Shanghai Henlius Biotech
NCT05216432 RECRUITING First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in Patients With Advanced Solid Tumors or Advanced Breast Cancer
Relay Therapeutics, Inc.
NCT06636435 RECRUITING A Phase I, First in Human Study of CBA-1205, Anti-DLK1 Monoclonal Antibody in Patients With Advanced Solid Tumors, Hepatocellular Carcinoma (HCC), Melanoma, and Pediatric Cancer
Chiome Bioscience Inc.
NCT06500052 RECRUITING A Study of BL-M17D1 in Patients With Locally Advanced or Metastatic HER2 Positive/Lower Expression Gastrointestinal Cancer and Other Solid Tumors
Sichuan Baili Pharmaceutical Co., Ltd.
NCT06533332 RECRUITING A Phase 1 Trial of ERX-315 in Participants With Advanced Solid Tumors
EtiraRx Australia Pty Ltd
NCT06493864 RECRUITING A Study of BL-B16D1 in Patients With Unresectable Locally Advanced or Metastatic Breast Cancer and Other Solid Tumors
Sichuan Baili Pharmaceutical Co., Ltd.
NCT06475131 RECRUITING A Study of BL-B16D1 in Patients With Locally Advanced or Metastatic Solid Tumors
Sichuan Baili Pharmaceutical Co., Ltd.
NCT06469008 RECRUITING A Study of BL-B16D1 in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma and Other Solid Tumors
Sichuan Baili Pharmaceutical Co., Ltd.
NCT05807035 RECRUITING Autologous Tumour Vaccine Trial
Vaxine Pty Ltd
NCT06549478 RECRUITING Biology-Guided Radiation Therapy for the Treatment of Patients With Bone Metastases
City of Hope Medical Center
NCT04064359 RECRUITING Safety and Preliminary Efficacy of OBT076 in Recurrent/Metastatic CD205+ Solid Tumors
Oxford BioTherapeutics Ltd
NCT06577987 RECRUITING Safety/Efficacy Study of CID-078 in Patients With Advanced Solid Tumor Malignancies
Circle Pharma
NCT05055609 RECRUITING Open-Label, Dose-Escalation With Expansion to Assess the Safety, Tolerability, and PK of TRE-515 in Subjects With Solid Tumors
Trethera
NCT06979674 RECRUITING Study of ESG406 in Adults With Solid Tumors
Shanghai Escugen Biotechnology Co., Ltd
NCT05259709 RECRUITING A Study of ImmunoPet Imaging Using 89Zr-DFO-REGN5054 in Adult Participants With Solid Cancers Treated With Cemiplimab
Regeneron Pharmaceuticals
NCT06983743 RECRUITING A Study of ERAS-0015 in Patients With Advanced or Metastatic Solid Tumors
Erasca, Inc.
NCT05357651 RECRUITING A Study to Assess the Safety and Efficacy of LB1410 in Participants With Advanced Solid Tumor or Lymphoma(Keyplus-001)
L & L Bio Co., Ltd., Ningbo, China
NCT05653882 ACTIVE NOT RECRUITING A Study Evaluating AB248 Alone or in Combination With Pembrolizumab in Adult Patients With Solid Tumors
Asher Biotherapeutics, Inc.
NCT07110090 RECRUITING Umbilical Cord Blood Megakaryocyte Injection (XJ-MK-002) for Cancer Therapy-Induced Thrombocytopenia (CTIT)
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT05107674 RECRUITING A Study of NX-1607 in Adults With Advanced Malignancies
Nurix Therapeutics, Inc.
NCT06783569 RECRUITING A First-in-Human Escalation and Expansion Study of Patients With Advanced Solid Tumors
JiaRay Group
NCT07163325 RECRUITING EP102 Safety and Efficacy in METTL3 Modulation in Advanced Solid Tumors
Epics Therapeutics
NCT07100847 RECRUITING Periprostatic Neurolysis in Prostate Cancer
University of Texas Southwestern Medical Center
NCT06239467 RECRUITING First-in-Human Study of OKI-219 in Advanced Solid Tumors and Advanced Breast Cancer
OnKure, Inc.
NCT05533463 ACTIVE NOT RECRUITING Phase I Study of HRS-4642 in Patients With Advanced Solid Tumors Harboring KRAS G12D Mutation
Jiangsu HengRui Medicine Co., Ltd.
NCT06739291 RECRUITING A Study of SIGX1094R in Patients With Advanced Solid Tumors
Signet Therapeutics
NCT07156253 RECRUITING Study of SYN818 With Olaparib for the Treatment of Locally Advanced or Metastatic Solid Tumors
Hangzhou SynRx Therapeutics Biomedical Technology Co., Ltd
NCT05932862 RECRUITING A Phase 1 Study of XL309 (ISM3091) Alone and in Combination in Participants With Advanced Solid Tumors
Exelixis
NCT05241834 ACTIVE NOT RECRUITING A Study of LOXO-260 in Cancer Patients With a Change in a Particular Gene (RET) That Has Not Responded to Treatment
Eli Lilly and Company
NCT07086768 NOT YET RECRUITING Dose-Escalation and Dose-Expansion Study of BSI-082 Monotherapy and Combined Therapy in Patients With Advanced or Metastatic Solid Tumors
Lei Zheng
NCT04047251 ACTIVE NOT RECRUITING A Study of FF-10850 Topotecan Liposome Injection in Advanced Solid Tumors Including Merkel Cell Carcinoma
Fujifilm Pharmaceuticals U.S.A., Inc.
NCT06398418 RECRUITING R-5780-01 In Combination With PD-1 Checkpoint Inhibitors (Checkpoint Protein on Immune Cells Called T Cells) in Patients With Solid Tumors
Rise Therapeutics LLC
NCT07067567 RECRUITING A Study of AK146D1 for Injection in Advanced Solid Tumors
Akeso
NCT06873659 RECRUITING SON-DP in Participants With Relapsed/Refractory Intolerant to Standard of Care Therapies for Advanced/Metastatic Solid Tumors
Qurgen Inc.
NCT06694480 RECRUITING Study of FID-022 in Participants With Advanced Solid Tumors
Fulgent Pharma LLC.
NCT07132541 RECRUITING Saleh's Technique for Pancreaticojejunostomy (Pancreatic Parenchymal Injection of N-butyl-2-cyanoacrylate)
Minia University
NCT05701488 RECRUITING SIRT With Tremelimumab and Durvalumab for Resectable HCC
Jiping Wang, MD, PhD
NCT06092580 RECRUITING Phase 1 Study of AWT020 in Advanced Cancer
Anwita Biosciences
NCT05076760 RECRUITING MEM-288 Oncolytic Virus Alone and in Combination With Standard of Care Therapy in Advanced Solid Tumors
Memgen, Inc.
NCT06806982 RECRUITING A Study of VRN101099 in Patients With HER2-Positive Solid Tumors
Voronoi, Inc
NCT06040541 RECRUITING Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors
Revolution Medicines, Inc.
NCT03611595 RECRUITING Cabozantinib in Combination With 13-cis-Retinoic Acid in Children With Relapsed or Refractory Solid Tumors
Peter Zage
NCT05836896 RECRUITING A Phase I Trial to Establish the Safety and Maximum Tolerated Dose of High-affinity Autologous BCMA-targeting Chimeric Antigen Receptor (CAR) T-cells in Patients With Relapsed and Refractory B-cell Malignancies
Technische Universität Dresden
NCT07139067 RECRUITING Phase I Clinical Study of YK1101 Injection for the Treatment of Advanced Solid Tumors
Peking University
NCT05835609 RECRUITING PM534 Administered Intravenously to Patients With Advanced Solid Tumors
PharmaMar
NCT07056556 RECRUITING A Study of BL-M09D1 in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer and Other Solid Tumors
Sichuan Baili Pharmaceutical Co., Ltd.
NCT07136558 NOT YET RECRUITING Evaluation of ICP-B794 in Patients With Advanced Solid Tumors
Beijing InnoCare Pharma Tech Co., Ltd.
NCT07135128 RECRUITING A Clinical Study of [225Ac]Ac-FAPI-XT(XT117) Injection in Patients With Advanced Solid Tumors
Xiaorong Sun
NCT06036121 ACTIVE NOT RECRUITING A Study of ADRX-0706 in Select Advanced Solid Tumors
Adcentrx Therapeutics
NCT05725291 RECRUITING AMT-116 in Patients With Advanced Solid Tumors
Multitude Therapeutics Inc.
NCT06487455 RECRUITING A Clinical Study of SPH7485 Tablets in the Treatment of Advanced Solid Tumors.
Shanghai Pharmaceuticals Holding Co., Ltd
NCT03132792 ACTIVE NOT RECRUITING AFPᶜ³³²T in Advanced HCC
Adaptimmune
NCT04429542 RECRUITING Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors
Bicara Therapeutics
NCT02099058 ACTIVE NOT RECRUITING A Study Evaluating the Safety, Pharmacokinetics (PK), and Preliminary Efficacy of ABBV-399 in Participants With Advanced Solid Tumors
AbbVie
NCT05906862 RECRUITING AMT-253 in Patients With Selected Advanced Solid Tumours
Multitude Therapeutics (Australia) Pty Ltd
NCT07119996 NOT YET RECRUITING Clinical Trial on the Protective Role of Vitamin B3 in Enhancing Immunotherapy for Bladder Cancer Patients
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
NCT05718219 ACTIVE NOT RECRUITING Safety, Tolerability, Pharmacokinetics and Preliminary Antitumor Activity of SIM0348 in Advanced Solid Tumors
Jiangsu Simcere Pharmaceutical Co., Ltd.
NCT05717348 ACTIVE NOT RECRUITING A Study of ES014 in Patients With Locally Advanced or Metastatic Solid Tumours
Elpiscience (Suzhou) Biopharma, Ltd.
NCT06547957 ACTIVE NOT RECRUITING A First-in-Human Study of EOS301984 as Monotherapy or Combination Therapy in Adult Participants With Advanced Solid Tumors
iTeos Therapeutics
NCT07117214 NOT YET RECRUITING A Phase I Study of [68Ga]Ga-DWJ155 in Patients With Breast and Lung Cancers
Novartis Pharmaceuticals
NCT07118709 NOT YET RECRUITING A Study of KC1086 in Patients With Advanced Solid Tumors
Beijing Konruns Pharmaceutical Co., Ltd.
NCT03893955 ACTIVE NOT RECRUITING A Study to Determine the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ABBV-927 With ABBV-368, Budigalimab (ABBV-181) and/or Chemotherapy in Participants With Locally Advanced or Metastatic Solid Tumors
AbbVie
NCT07118176 RECRUITING Determining the Biodistribution of an Imaging Tracer (68Ga-FAPi-46) in Patients With Solid Tumors or Hematologic Cancers
Jonsson Comprehensive Cancer Center
NCT05836948 RECRUITING The Clinical Study of SHR-9839 for Injection in Patients With Advanced Solid Tumors
Shanghai Hengrui Pharmaceutical Co., Ltd.
NCT05279300 RECRUITING A Study of CS5001 in Patients With Advanced Solid Tumors and Lymphomas
CStone Pharmaceuticals
NCT07110883 RECRUITING A Clinical Study of SYS6023 in Patients With Advanced Solid Tumors
CSPC Megalith Biopharmaceutical Co.,Ltd.
NCT06375564 RECRUITING Clinical Evaluation of 177Lu-AB-3PRGD2 in Various Solid Tumors With Integrin αvβ3 Positive Expression
The First Affiliated Hospital of Xiamen University
NCT05226507 ACTIVE NOT RECRUITING A Phase 1 Clinical Study of NXP800 in Subjects With Advanced Cancers and Expansion in Subjects With Ovarian Cancer
Nuvectis Pharma, Inc.
NCT07100249 RECRUITING A Study of HDM2012 in Patients With Advanced Solid Tumor
Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.
NCT07110363 NOT YET RECRUITING A Clinical Study of BT02 in Treating Patients With Advanced Lung Cancer
Biotroy Therapeutics
NCT07107178 NOT YET RECRUITING A Clinical Study of BT02 for the Treatment of Patients With Advanced Malignant Melanoma
Biotroy Therapeutics
NCT04778839 RECRUITING Study of Paclitaxel Micelles for Injection in Chinese Patients With Advanced Solid Tumors.
First Affiliated Hospital of Zhejiang University
NCT05740202 ACTIVE NOT RECRUITING A Trial of SHR-7367 in Subjects With Advanced Solid Tumors
Shanghai Hengrui Pharmaceutical Co., Ltd.
NCT04046133 ACTIVE NOT RECRUITING Phase 1b/II Trial of Pembrolizumab Plus IMRT in Stage III/IV Carcinoma of Anus
Cardiff University
NCT07100925 NOT YET RECRUITING A Study of Tolododekin Alfa (ANK-101) in Renal Allograft Recipients With High Risk Cutaneous Squamous Cell Carcinoma
Ankyra Therapeutics, Inc
NCT05718557 ACTIVE NOT RECRUITING Study of PYX-106 in Solid Tumors
Pyxis Oncology, Inc
NCT07101549 NOT YET RECRUITING Treating Nectin-4-positive Advanced Solid Tumors With R-Star001 (Nectin-4-CART-IL18)
changjianhua
NCT07072325 NOT YET RECRUITING Safety, Tolerability, PK, and Efficacy of CD-001 in Advanced Head & Neck Cancers
West China Hospital
NCT03872947 ACTIVE NOT RECRUITING A Study of TRK-950 in Combinations With Anti-Cancer Treatment Regimens in Patients With Advanced Solid Tumors
Toray Industries, Inc
NCT04572451 RECRUITING Safety of SBRT With Anti-PD1 and Anti-IL-8 for the Treatment of Multiple Metastases in Advanced Solid Tumors and Melanoma
Yana Najjar
NCT05735496 ACTIVE NOT RECRUITING Clinical Trial of the TQB2102 Injection in Patients With Advanced Cancers
Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.
NCT07098052 RECRUITING A Study of HDM2020 in Patients With Advanced Solid Tumors
Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.
NCT06463340 RECRUITING Study of SGR-3515 In Participants With Advanced Solid Tumors.
Schrödinger, Inc.
NCT06756035 RECRUITING CT-95 in Advanced Cancers Associated With Mesothelin Expression
Context Therapeutics Inc.
NCT02498912 ACTIVE NOT RECRUITING Cyclophosphamide Followed by Intravenous and Intraperitoneal Infusion of Autologous T Cells Genetically Engineered to Secrete IL-12 and to Target the MUC16ecto Antigen in Patients With Recurrent MUC16ecto+ Solid Tumors
Memorial Sloan Kettering Cancer Center
NCT05617755 ACTIVE NOT RECRUITING AB-1015, an Integrated Circuit T (ICT) Cell Therapy in Patients With Platinum Resistant Epithelial Ovarian Cancer
Arsenal Biosciences, Inc.
NCT06220838 RECRUITING Study SC-101 in Subjects With Advanced Malignancies
Tianjin ConjuStar Biologics Co., Ltd.
NCT07088588 NOT YET RECRUITING Study of SYN608 for the Treatment of Advanced or Metastatic Solid Tumors
Hangzhou SynRx Therapeutics Biomedical Technology Co., Ltd
NCT06761937 RECRUITING Thermoradiotherapy for Locally Advanced Head and Neck Cancer Patients
Erasmus Medical Center
NCT06428500 ACTIVE NOT RECRUITING QTX3046 in Patients With KRAS G12D Mutations
Quanta Therapeutics
NCT06644755 RECRUITING First-in-Human Trial of DS-2243a in Participants With Advanced Solid Tumors
Daiichi Sankyo
NCT05217693 RECRUITING A First-in-human of Multiplle Doses of BB-1705 in Subjects With Locally Advanced/Metastatic Solid Tumors
Bliss Biopharmaceutical (Hangzhou) Co., Ltd
NCT06992713 RECRUITING A Clinical Study Evaluating H1710 for Injection in Participants With Advanced Solid Tumors
Shenzhen Hepalink Pharmaceutical Group Co., Ltd.
NCT07071090 RECRUITING A Study of DC50292A Tablet in Patients With MTAP-deleted Advanced or Metastatic Solid Tumors
Heronova Pharmaceuticals
NCT03772561 RECRUITING Phase I Study of AZD5363 + Olaparib + Durvalumab in Patients With Advanced or Metastatic Solid Tumor Malignancies
National University Hospital, Singapore
NCT05701709 RECRUITING Phase I Study of SHR-A2102 in Patients With Advanced Solid Tumors
Shanghai Hengrui Pharmaceutical Co., Ltd.
NCT06894745 RECRUITING PET [89Zr]DFO-starPEG in Solid Tumors
Robert Flavell, MD, PhD
NCT06666270 RECRUITING Study of SYN818 for the Treatment of Advanced or Metastatic Solid Tumors
Hangzhou SynRx Therapeutics Biomedical Technology Co., Ltd
NCT01843413 ACTIVE NOT RECRUITING Stereotactic Radiosurgery in Treating Patients With Large Brain Metastases
Case Comprehensive Cancer Center
NCT06826313 RECRUITING A Study of Intravenous VRT106 for Locally Advanced or Metastatic Solid Tumors
Guangzhou Virotech Pharmaceutical Co., Ltd.
NCT06942104 RECRUITING Imaging of Solid Tumors Using 18F-TRX
Rahul Aggarwal
NCT06963814 RECRUITING Study of HC006 in Combination With a PD-1 Inhibitor in Patients With Advanced Solid Tumors
HC Biopharma Inc.
NCT06929663 RECRUITING A Study of AK146D1 for Injection in the Treatment of Advanced Solid Tumors
Akeso
NCT05881525 RECRUITING NY-ESO-1 TCR-T Cells for NY-ESO-1 Positive Subjects With Advanced Solid Tumors
TCRCure Biopharma Ltd.
NCT04457232 ACTIVE NOT RECRUITING Prospective Exploratory Study of FAPi PET/CT in Prostate Cancer With Histopathology Validation
Jonsson Comprehensive Cancer Center
NCT06128148 RECRUITING Phase I Study of JYP0322 in ROS1 Fusion-Positive Solid Tumors
Guangzhou JOYO Pharma Co., Ltd
NCT04511845 ACTIVE NOT RECRUITING A Dose-Escalation Study of SPYK04 in Patients With Locally Advanced or Metastatic Solid Tumors (With Expansion).
Chugai Pharmaceutical
NCT06993870 RECRUITING Phase I Study of HBT-708 for Patients With Advanced Solid Tumors
Shenyang Sunshine Pharmaceutical Co., LTD.
NCT07060014 NOT YET RECRUITING NALIRIFOX (Nal-IRI Plus 5-FU/LV Plus Oxaliplatin) as First-Line Treatment for Patients With Advanced Small Intestine and Appendiceal Cancers
The Methodist Hospital Research Institute
NCT04046575 ACTIVE NOT RECRUITING Radiation Dose Intensification With Accelerated Hypofractionated Intensity Modulated Radiation Therapy and Concurrent Carboplatin and Paclitaxel for Inoperable Esophageal Cancer
Washington University School of Medicine
NCT05857969 RECRUITING Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling
Florida International University
NCT02474368 ACTIVE NOT RECRUITING Study Evaluating a Stereotactic Boost/Treatment for Recurrent or Metastatic Cancer of the Head and Neck
Dana-Farber Cancer Institute
NCT06719362 RECRUITING A Clinical Trial to Evaluate the Safety, Tolerability and Clinical Efficacy of M3T01 Monotherapy and in Combination With Pembrolizumab and Other Systemic Therapies
Providence Health & Services
NCT02974738 ACTIVE NOT RECRUITING A Trial of Belzutifan (PT2977, MK-6482) Tablets In Patients With Advanced Solid Tumors (MK-6482-001)
Peloton Therapeutics, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
NCT03336606 ACTIVE NOT RECRUITING Study of MEDI0562 Prior to Surgical Resection in Head and Neck Squamous Cell Carcinoma (HNSCC) or Melanoma
Providence Health & Services
NCT07057349 NOT YET RECRUITING CSB-321 Ph 1 in Immunotherapy for the Treatment of Cancer
Cytosite Biopharma Inc.
NCT07053904 ENROLLING BY INVITATION Phase I Open-Label Study of P1101 Followed by P1801 in Advanced Solid Tumors
PharmaEssentia
NCT07053735 NOT YET RECRUITING An Exploratory Clinical Study of Nimotuzumab in Bladder - Sparing Chemoradiotherapy for Muscle - Invasive Bladder Cancer
Peking University First Hospital
NCT06980454 ACTIVE NOT RECRUITING Phase I PK Comparison of HLX05 vs. Erbitux® in Healthy Chinese Males: Safety, Immunogenicity, and Pharmacokinetics
Shanghai Henlius Biotech
NCT02112565 ACTIVE NOT RECRUITING RNR Inhibitor COH29 in Treating Patients With Solid Tumors That Are Refractory to Standard Therapy or For Which No Standard Therapy Exists
City of Hope Medical Center
NCT07045428 NOT YET RECRUITING 68Ga-GP-01 Injection in Solid Tumors Participants
GrandPharma (China) Co., Ltd.
NCT03832855 ACTIVE NOT RECRUITING Assessing the Immunogenicity of pING-hHER3FL
Herbert Lyerly
NCT04796220 RECRUITING Focused Ultrasound and Gemcitabine in Breast Cancer
Patrick Dillon, MD
NCT07050459 RECRUITING A Phase I Study of SIM0686 in Participants With Locally Advanced/Metastatic Solid Tumors
Jiangsu Simcere Pharmaceutical Co., Ltd.
NCT06548217 ACTIVE NOT RECRUITING A Phase I Study of ONO-4538HSC in Subjects With Advanced or Metastatic Solid Tumors
Ono Pharmaceutical Co., Ltd.
NCT04721015 ACTIVE NOT RECRUITING Study of Intravenous (IV) ABBV-637 Alone or in Combination With IV Docetaxel/Osimertinib to Assess Adverse Events and Change in Disease Activity in Adult Participants With Relapsed/Refractory (R/R) Solid Tumors
AbbVie
NCT05277766 RECRUITING Intraperitoneal Aerosolized Nanoliposomal Irinotecan (Nal-IRI) in Peritoneal Carcinomatosis From Gastrointestinal Cancer
University Hospital, Ghent
NCT04740424 RECRUITING FS222 First in Human Study in Patients With Advanced Malignancies
invoX Pharma Limited
NCT06415487 RECRUITING ACE2016 in Adult Subjects With Locally Advanced or Metastatic Solid Tumors Expressing Epidermal Growth Factor Receptor (EGFR)
Acepodia Biotech, Inc.
NCT06410131 RECRUITING Study in Patients With Advanced Solid Tumors to Evaluate the Safety of FTL008.16
Sound Biopharmaceuticals Ltd.
NCT07045454 RECRUITING A Study of MHB118C Injection in Patients With Advanced Solid Tumors
Minghui Pharmaceutical (Hangzhou) Ltd
NCT04827810 RECRUITING A Phase I Safety and Pharmacokinetic Study of Gamitrinib Administered Intravenously to Patients With Advanced Cancer
Fox Chase Cancer Center
NCT06163391 RECRUITING A Study to Assess Safety and Efficacy of SOT201 in Patients With Advanced/Metastatic Cancer
SOTIO Biotech AG
NCT04648202 ACTIVE NOT RECRUITING FS120 Phase 1/1b Study in Patients With Advanced Malignancies
invoX Pharma Limited
NCT06076291 ACTIVE NOT RECRUITING An Open-label Study of SG1827 in Subjects With Advanced Solid Tumors
Hangzhou Sumgen Biotech Co., Ltd.
NCT04603001 ACTIVE NOT RECRUITING Study of Oral LY3410738 in Patients With Advanced Hematologic Malignancies With IDH1 or IDH2 Mutations
Eli Lilly and Company
NCT06240728 RECRUITING A Study of NPX887 for Participants With Solid Tumors Known to Express B7-H7/HHLA2
NextPoint Therapeutics, Inc.
NCT05354323 ACTIVE NOT RECRUITING NECVAX-NEO1 in Addition to Checkpoint Inhibitor in Patients With Solid Tumors
NEC OncoImmunity AS
NCT07038044 NOT YET RECRUITING Safety and Efficacy of an Arginine-Restricted Diet in Patients With Solid Tumors
West China Hospital
NCT05785754 RECRUITING DCSZ11 as a Monotherapy and in Combination in Patients With Advanced or Metastatic Solid Tumors
DynamiCure Biotechnology
NCT04997993 RECRUITING Leflunomide in Patients With PTEN-Altered Advanced Solid Malignancies and HER2 Negative Breast Cancer
Deborah Doroshow
NCT05857332 RECRUITING SG1906 for CLDN18.2-Positive Solid Tumors
Hangzhou Sumgen Biotech Co., Ltd.
NCT06431594 RECRUITING A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Clinical Activity of GSK5733584 for Injection in Participants With Advanced Solid Tumors
GlaxoSmithKline
NCT06601218 RECRUITING Impact of Daily Oral Cannabis Doses in Patients With Cancer
Shanna Babalonis, PhD
NCT07028047 NOT YET RECRUITING Evaluation of WGc-043 Injection in Advanced Solid Tumors: Phase I Study
Sun Yat-sen University
NCT03917043 RECRUITING APG-2449 in Patients With Advanced Solid Tumors
Ascentage Pharma Group Inc.
NCT05329103 RECRUITING A Study to Evaluate PEEL-224 in Patients With Advanced Solid Tumors
Peel Therapeutics Inc
NCT06349811 RECRUITING A Study of BL-M05D1 in Patients With Locally Advanced or Metastatic Solid Tumors
Sichuan Baili Pharmaceutical Co., Ltd.
NCT07021534 RECRUITING Hepatic Artery Transfusion of NKG2D CAR-NK Cells Followed by Intravenous Infusion of NKG2D CAR-T Cells to Treat Patients With Advanced Solid Tumors With Liver Metastases Who Have Failed Standard Treatments: a Phase I Exploratory Clinical Trial
Zhejiang University
NCT07016997 RECRUITING A Phase I, First in Human Study of CBA-1535, T Cell Engager(5T4/CD3/5T4) in Patients With Advanced Solid Tumors.
Chiome Bioscience Inc.
NCT04412616 RECRUITING ZZ06 in Adult Patients With Advanced Solid Tumor Malignancies
Changchun Intellicrown Pharmaceutical Co. LTD
NCT06883149 RECRUITING PIN in Combination With Anti-PD1 in Previously Treated Solid Tumor
Chinese PLA General Hospital
NCT06028373 RECRUITING A Study of ATG-031 in Advanced Solid Tumors or B-cell Non-Hodgkin Lymphomas
Antengene Biologics Limited
NCT05205109 RECRUITING A Study to Assess the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of ATG 037 Monotherapy and Combination Therapy With Pembrolizumab in Patients With Advanced Solid Tumors
Antengene Therapeutics Limited
NCT02608385 ACTIVE NOT RECRUITING Study of PD1 Blockade by Pembrolizumab With Stereotactic Body Radiotherapy in Advanced Solid Tumors
University of Chicago
NCT07004296 RECRUITING A Study of HDM2005 in Patients With Advanced Solid Tumor
Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.
NCT06063681 RECRUITING A Study of SR-8541A (ENPPI Inhibitor) in Advanced/Metastatic Solid Tumors
Stingray Therapeutics
NCT06963281 RECRUITING Study of IBI3020 Treatment in Participants With Late-Stage Solid Tumors
Innovent Biopharmaceutical Technology (Hangzhou) Co., LTD.
NCT05740956 RECRUITING A Study of Hansoh (HS)-10502 in Patients With Advanced Solid Tumors
Jiangsu Hansoh Pharmaceutical Co., Ltd.
NCT03155061 ACTIVE NOT RECRUITING Study of ONO-4578 With and Without ONO-4538 in Subjects Advanced or Metastatic Solid Tumors
Ono Pharmaceutical Co., Ltd.
NCT06253195 ACTIVE NOT RECRUITING BGB-43395 Alone or as Part of Combination Therapies in Chinese Participants With HR+/HER2- Breast Cancer and Other Advanced Solid Tumors
BeiGene
NCT06878612 RECRUITING a Polyphenol Whole Tumor Cell Vaccine in Patients With Advanced Malignant Solid Tumors
Xingchen Peng
NCT06978062 NOT YET RECRUITING Peri-operative Treatment of Resectable Gastroesophageal Cancer Using Bemarituzumab (BEMA) Plus Perioperative Treatment
European Organisation for Research and Treatment of Cancer - EORTC
NCT06898255 RECRUITING A Phase I Study to Evaluate GFS202A in Advanced Solid Tumor Patients With Pre-cachexia or Cachexia
Genfleet Therapeutics (Shanghai) Inc.
NCT07001592 RECRUITING Intra-tumoral (IT) Injection of vvDD-hIL2-2-RG-1 for Metastatic Gastrointestinal and Peritoneal Tumors
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
NCT06954077 RECRUITING A Study of BL-M09D1 in Patients With Locally Advanced or Metastatic Gastrointestinal Tumors and Other Solid Tumors
Sichuan Baili Pharmaceutical Co., Ltd.
NCT06998173 NOT YET RECRUITING Phase 1 Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of DAT-1604 in Advanced Solid Tumor
Danatlas Pharmaceuticals Co., Ltd
NCT05518253 RECRUITING A Clinical Study of CD70-targeted CAR-T in the Treatment of CD70-positive Advanced/Metastatic Solid Tumors
Weijia Fang, MD
NCT04866641 RECRUITING Safety and Tolerability Study for T-1201 Injection 100 mg Kit in Patients With Advanced Solid Tumors
Taivex Therapeutics Corporation
NCT05704985 ACTIVE NOT RECRUITING Evaluating Safety and Biomarkers Using DK210 (EGFR) for Locally Advanced or Metastatic EGFR+ Tumors
DEKA Biosciences
NCT06644573 NOT YET RECRUITING Evaluating the Efficacy and Safety of PROSOMNIA Sleep Therapy™ in Patients With Sleep Deprivation and Chronic Insomnia
Nyree Penn
NCT06902350 RECRUITING Safety, Pharmacokinetics and Preliminary Efficacy of CS231295 in Advanced Solid Tumors
Chipscreen Biosciences, Ltd.
NCT03821935 ACTIVE NOT RECRUITING Study to Determine the Safety, Tolerability, Pharmacokinetics and Recommended Phase 2 Dose (RP2D) of Livmoniplimab (ABBV-151) as a Single Agent and in Combination With Budigalimab (ABBV-181) in Participants With Locally Advanced or Metastatic Solid Tumors
AbbVie
NCT06337084 RECRUITING Diagnostic Efficacy and Dosimetry of MNPR-101-DFO*-89Zr in Patients With Solid Tumors
Monopar Therapeutics
NCT04616534 ACTIVE NOT RECRUITING Testing the Addition of an Anti-cancer Drug, Elimusertib (BAY 1895344) ATR Inhibitor, to the Chemotherapy Treatment (Gemcitabine) for Advanced Pancreatic and Ovarian Cancer, and Advanced Solid Tumors
National Cancer Institute (NCI)
NCT06912152 RECRUITING MT027 in Patients With Advanced Peritoneal Malignancies or Abdominal Metastatic Solid Tumors
Zhejiang University
NCT06246968 RECRUITING A Study of Pembrolizumab and Cryoablation in People With Breast Cancer
Memorial Sloan Kettering Cancer Center
NCT06617169 RECRUITING Dose-Escalation of MNPR-101-PCTA-177Lu in Solid Tumors
Monopar Therapeutics
NCT05048368 NOT YET RECRUITING Pharmacokinetics Study of Larotinib in Subjects With Impaired Hepatic Function
Sunshine Lake Pharma Co., Ltd.
NCT03440450 ACTIVE NOT RECRUITING A Phase 1 Dose-escalation Study of FF-10832 for Treatment of Solid Tumors Including Biliary Tract Cancer
Fujifilm Pharmaceuticals U.S.A., Inc.
NCT05678010 ACTIVE NOT RECRUITING A Study of AZD1390 and Stereotactic Body Radiotherapy (SBRT) for People With Metastatic Solid Tumor Cancer
Memorial Sloan Kettering Cancer Center
NCT02663297 ACTIVE NOT RECRUITING Administration of T Lymphocytes for Prevention of Relapse of Lymphomas
UNC Lineberger Comprehensive Cancer Center
NCT04137536 ACTIVE NOT RECRUITING A Study of Armed, Activated T-Cells in Patients With Advanced Pancreatic Cancer
Memorial Sloan Kettering Cancer Center
NCT06970795 RECRUITING A Study of SYS6040 for Injection in Patients With Advanced Solid Tumors
CSPC Megalith Biopharmaceutical Co.,Ltd.
NCT06958679 RECRUITING Evaluation of SYS6005 in Patients With Advanced Malignant Tumor
CSPC Megalith Biopharmaceutical Co.,Ltd.
NCT06307925 RECRUITING A Phase I Study to Evaluate the Safety, Pharmacokinetics and Antitumor Activity of HC010 in Patients With Advanced Solid Tumors
HC Biopharma Inc.
NCT06968572 RECRUITING Phase I Study of HSK41959 in Solid Tumors With MTAP Deletion
Haisco Pharmaceutical Group Co., Ltd.
NCT06966583 NOT YET RECRUITING NAD+ Supplement(NMN)With Radioimmunotherapy in Advanced NSCLC
Sichuan University
NCT05765851 ACTIVE NOT RECRUITING A Study of DS-1103a Combination Therapy in Participants With Advanced Solid Tumors
Daiichi Sankyo
NCT06963398 NOT YET RECRUITING A Study of HS-10529 in KRAS G12D Patients With Advanced Solid Tumors
Jiangsu Hansoh Pharmaceutical Co., Ltd.
NCT06963502 NOT YET RECRUITING A Phase Ib Study of HS-10370 in Addition to Other Anti-cancer Therapies in Patients With Advanced Solid Tumors
Jiangsu Hansoh Pharmaceutical Co., Ltd.
NCT06962254 RECRUITING Imatinib and Trametinib for KRAS-mutated Solid Tumor
China Medical University Hospital
NCT06304571 RECRUITING A Study of HC006 in Subjects With Advanced Solid Tumors
HC Biopharma Inc.
NCT06954558 RECRUITING A Single-Arm, Open-Label, Phase I Study of GK01 for Advanced Solid Tumor
Tianjin Medical University Cancer Institute and Hospital
NCT06934616 NOT YET RECRUITING A Phase I, First-in-Human Study of GB268 (PD-1/CTLA-4/VEGF Trispecific Antibody) in Advanced Solid Tumors
Genor Biopharma Co., Ltd.
NCT05598151 RECRUITING Dose Escalation and Expansion Study of HM97662 in Advanced or Metastatic Solid Tumors
Hanmi Pharmaceutical Company Limited
NCT05167071 ACTIVE NOT RECRUITING HBM4003 Combine With Toripalimab in Patients With Advanced NEN and Other Solid Tumors Study
Harbour BioMed (Guangzhou) Co. Ltd.
NCT06907628 RECRUITING A Trial of SHR-3792 Injection in Patients With Advanced Solid Tumors
Suzhou Suncadia Biopharmaceuticals Co., Ltd.
NCT06188624 RECRUITING Clinical Trial of TQB2922 for Injection in Patients With Advanced Cancers
Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.
NCT06944457 RECRUITING Clinical Trial to Evaluate the Safety, Tolerability and Pharmacokinetics of MPD-1 in Patients With Advanced Solid Tumor
Pharosgen Co.,Ltd
NCT05978492 RECRUITING A Study of TXN10128 in Subjects With Solid Tumors
Txinno Bioscience Inc.
NCT05967533 RECRUITING The Immune Effects of Fermented Wheat Germ Nutritional Supplementation in Patients With Advanced Solid Tumor Cancers Being Treated With Standard of Care Checkpoint Inhibitors
University of California, Davis
NCT06932094 NOT YET RECRUITING Phase 1 Clinical Study of QLS5132 Monotherapy in Advanced Solid Tumors
Qilu Pharmaceutical Co., Ltd.
NCT06936735 NOT YET RECRUITING Phase I Study of HS-20108 in Participants With Advanced Solid Tumors
Hansoh BioMedical R&D Company
NCT05749432 RECRUITING A Phase I Study of Hemay181 in Patients With Advanced Solid Tumors
Ganzhou Hemay Pharmaceutical Co., Ltd
NCT05919537 ACTIVE NOT RECRUITING Study of an Anti-HER3 Antibody, HMBD-001, With or Without Chemotherapy in Patients With Solid Tumors Harboring an NRG1 Fusion or HER3 Mutation
Hummingbird Bioscience
NCT06235983 ACTIVE NOT RECRUITING A Study of LY3537982 in Chinese Participants With Advanced Solid Tumors
Eli Lilly and Company
NCT06475937 RECRUITING A Study of DM001 in Patients With Advanced Solid Tumors
Xadcera Biopharmaceutical (Suzhou) Co., Ltd.
NCT06925659 NOT YET RECRUITING A Study of QLM2011 in Subjects With Advanced Solid Tumors
Qilu Pharmaceutical (Hainan) Co., Ltd.
NCT04706962 ACTIVE NOT RECRUITING TH1902 in Patients With Advanced Solid Tumors
Theratechnologies
NCT06462365 RECRUITING Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT)
Tr1X, Inc.
NCT05473624 RECRUITING Study of HRS-1167 as Monotherapy in Patients With Advanced Solid Tumors
Jiangsu HengRui Medicine Co., Ltd.
NCT06462716 ACTIVE NOT RECRUITING A Phase l Study of By101298, an Oral DNA-PK Inhibitor, in Patients With Advanced Solid Tumors
Chengdu Baiyu Pharmaceutical Co., Ltd.
NCT06094556 RECRUITING An Open Phase I Clinical Trial of SHR-1826 for Injection in Patients With Advanced Solid Tumors
Suzhou Suncadia Biopharmaceuticals Co., Ltd.
NCT05969314 ACTIVE NOT RECRUITING To Check Safety of Ayurvedic Oral Cannabis in Breast and Head and Neck Cancer
Tata Memorial Hospital
NCT06258304 RECRUITING A Dose Escalation and Expansion Study of GIGA-564 in Participants With Locally Advanced or Metastatic Solid Tumor Malignancies
GigaGen, Inc.
NCT05528341 RECRUITING NKG2D-CAR-NK92 Cells Immunotherapy for Solid Tumors
Henan Medical University
NCT06621563 RECRUITING Phase Ib Trial of HS-20117 in Combination With Other Drugs in Advanced Solid Tumors
Hansoh BioMedical R&D Company
NCT06710379 RECRUITING A Study of ADRX-0405 in Subjects With Select Advanced Solid Tumors
Adcentrx Therapeutics
NCT06096974 RECRUITING Pan-RAS Inhibitor YL-17231 in Patients With Advanced Solid Tumors Harboring Mutations in KRAS, HRAS, or NRAS
Shanghai YingLi Pharmaceutical Co. Ltd.
NCT04685473 ACTIVE NOT RECRUITING Safety and Tolerability Study for T-1101 (Tosylate) Capsules to Treat Advanced Refractory Solid Tumors
Taivex Therapeutics Corporation
NCT05495295 RECRUITING First-in-human Trial of PhOx430, a First-in-class Acetylglucosaminyltransferase V Inhibitor, in Advanced Solid Tumours
Phost'In Therapeutics
NCT05544240 RECRUITING Phase 1 Trial of SYNC-T - Immunotherapy for Patients With Advanced/Metastatic Solid Tumors
Williams Cancer Foundation
NCT06913218 NOT YET RECRUITING A Study of mRNA Vaccines AK154 Monotherapy or in Combination With AK104/AK112,and Sequential mFOLFIRINOX in Surgically Resected PDAC
Akeso
NCT04751786 ACTIVE NOT RECRUITING Dose Escalation Study of Immunomodulatory Nanoparticles
Radboud University Medical Center
NCT05868226 RECRUITING PRE-I-SPY Phase I/Ib Oncology Platform Program
QuantumLeap Healthcare Collaborative
NCT06885645 NOT YET RECRUITING First-In-Human Study in Participants With Advanced Solid Tumors
Chengdu Kanghong Biotech Co., Ltd.
NCT06446713 RECRUITING PIRATES: Image-guided Hyper-fractioned Dose-escalation With Proton Therapy for Head and Neck Cancer
University Medical Center Groningen
NCT05477849 RECRUITING A Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Biologic Effect of VG2025 in Patients with Solid Tumors
Shanghai Virogin Biotech Co., Ltd.
NCT06796699 RECRUITING A Phase Ia/Ib Clinical Study of GH56 Capsules in Subjects With MTAP-Deleted Advanced Solid Tumors
Suzhou Genhouse Bio Co., Ltd.
NCT06897228 RECRUITING PANK-003 Cell Injection Combined with Standard Adjuvant Chemotherapy After Surgery in Patients with Solid Tumors
Shenzhen Celconta Life Science Co., Ltd.
NCT06716619 RECRUITING A Phase I Trial of Tumor-Associated Lymph Node T-Cell Injection With Advanced Malignant Solid Tumors
Guangzhou FineImmune Biotechnology Co., LTD.
NCT04877717 ACTIVE NOT RECRUITING A Study of SHR-A1904 in Patients With Advanced Solid Cancer
Shanghai Hengrui Pharmaceutical Co., Ltd.
NCT06587295 RECRUITING Intramuscular ACM-CpG Monotherapy in Patients With Advanced/Metastatic Solid Tumors With Prior Response to Immunotherapy Alone or in Combination With Chemotherapy
National Cancer Centre, Singapore
NCT05828459 RECRUITING First-in-human Study of OT-A201 in Patients With Selected Hematological Malignancies and Solid Tumors
Onward Therapeutics
NCT06883539 RECRUITING A Phase I Study of LXP1788 Injection with Advanced Solid Tumors.
LaunXP Biomedical Co., Ltd.
NCT06541639 RECRUITING EVM16 Injection As a Single and Combination with Tislelizumab in Solid Tumors
Peking University
NCT04998422 RECRUITING A Study of HG381 Administered to Patients With Advanced Solid Tumors
HitGen Inc.
NCT06046742 RECRUITING A Study of Intravenous M1-c6v1 for Locally Advanced or Metastatic Solid Tumors
Guangzhou Virotech Pharmaceutical Co., Ltd.
NCT06872580 NOT YET RECRUITING A Study of QLS1209 in theTreatment of Patients With Advanced Solid Tumors
Qilu Pharmaceutical Co., Ltd.
NCT06167317 RECRUITING Study of GS-0201 Alone and in Combination in Participants With Advanced Solid Tumors
Gilead Sciences
NCT06707610 RECRUITING A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), and Antitumor Activity of ALK202 in Participants with Advanced Solid Tumors
Shanghai Allink Biotherapeutics Co., Ltd.
NCT06868849 RECRUITING A Study of JMT203 in Patients With Cancer Cachexia
Shanghai JMT-Bio Inc.
NCT06595329 RECRUITING Comparison Between Epidural Analgesia and Intrathecal Opioid Analgesia for Pain Management in Open Nephrectomy
University Hospital of Split
NCT04196257 RECRUITING BP1001-A in Patients With Advanced or Recurrent Solid Tumors
Bio-Path Holdings, Inc.
NCT06730386 RECRUITING A Phase I Study of AK138D1 in the Treatment of Advanced Solid Tumors
Akeso
NCT05907980 RECRUITING A Phase I Study of ROSE12 Alone and in Combination With Other Anti-tumor Agents in Patients With Solid Tumors
Chugai Pharmaceutical
NCT06443489 RECRUITING A Trial of SHR-4849 in Advanced Solid Tumors
Suzhou Suncadia Biopharmaceuticals Co., Ltd.
NCT06069570 RECRUITING Safety Study for a Gamma Delta T Cell Product Used With Low Dose Radiotherapy in Patients With Locally Advanced or Metastatic NSCLC or Solid Tumors With Bone Metastases
Kiromic BioPharma Inc.
NCT06005740 RECRUITING A Phase 1, First in Human Study of TORL-4-500 in Patients With Advanced Cancer
TORL Biotherapeutics, LLC
NCT06035744 RECRUITING CLN-617 Alone and in Combination With Pembrolizumab in Patients With Advanced Solid Tumors
Cullinan Therapeutics Inc.
NCT03943004 RECRUITING Trial of DFP-14927 in Advanced Solid Tumors
Delta-Fly Pharma, Inc.
NCT05607498 RECRUITING First in Human Study of EMB-07 in Locally Advanced/Metastatic Solid Tumors or Relapse/Refractory Lymphoma
EpimAb Biotherapeutics (Suzhou)Co., Ltd.
NCT06687070 RECRUITING APG-2449 Monotherapy or in Combination With PLD in Patients With Platinum-resistant Recurrent OC or Advanced ST
Ascentage Pharma Group Inc.
NCT05701306 RECRUITING APG-115 Alone or in Combination With APG-2575 in Children With Recurrent or Refractory Neuroblastoma or Solid Tumors
Ascentage Pharma Group Inc.
NCT06484816 RECRUITING TGRX-1942 Chinese Phase I for Advanced Solid Tumor And/or Relapsed/Refractory Hematologic Malignancies
Shenzhen TargetRx Co., Ltd.
NCT06394414 RECRUITING A Phase 1 Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of YL201 in Advanced Solid Tumors
MediLink Therapeutics (Suzhou) Co., Ltd.
NCT06571422 RECRUITING Phase I Study of WJ47156 Monotherarpy and in Combination With Other Therapy in Advanced Solid Tumors
Shanghai Junshi Bioscience Co., Ltd.
NCT06831539 RECRUITING Impact of PEG Bowel Preparation on Gut Microbiome Composition Recovery
Centre hospitalier de l'Université de Montréal (CHUM)
NCT04643574 ACTIVE NOT RECRUITING NeoTIL in Advanced Solid Tumors
Centre Hospitalier Universitaire Vaudois
NCT05580991 ACTIVE NOT RECRUITING Intratumoral CAN1012(selective TLR7 Agonist) in Subjects with Solid Tumors
Canwell Biotech Limited
NCT06051760 RECRUITING NV-001 in the Treatment of Advanced Solid Tumors
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT06801470 RECRUITING A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of CD-001 in Patients With Advanced Solid Tumors
CD (Suzhou) Biopharma Co., Ltd.
NCT04762641 RECRUITING This is a Study to Evaluate the Safety and Tolerability of ABL503, and to Determine the Maximum Tolerated Dose (MTD) and Recommended Phase 2 Dose (RP2D) of ABL503 in Subjects with Any Progressive Locally Advanced or Metastatic Solid Tumors
ABL Bio, Inc.
NCT04701645 RECRUITING Microdevice In Ovarian, Fallopian Tube, And Peritoneal Cancer
Brigham and Women's Hospital
NCT03212404 ACTIVE NOT RECRUITING Phase 1 Study of CK-301 (Cosibelimab) as a Single Agent in Subjects With Advanced Cancers
Checkpoint Therapeutics, Inc.
NCT04872166 RECRUITING A Study of BTX-A51 in People With Advanced Solid Tumor and Breast Cancer
Edgewood Oncology Inc.
NCT06800196 NOT YET RECRUITING A Study of KNT-0916 in Treatment of Unresectable or Metastatic Solid Tumors with FGFR2 Alterations
KinoTeck Therapeutics Co., Ltd
NCT06224855 RECRUITING A Study of DXC006 in Patients With Advanced Solid Tumors and Hematologic Malignancies
Hangzhou DAC Biotechnology Co., Ltd.
NCT05341557 RECRUITING A Phase 1 Study of BPI-371153 in Subjects with Advanced Solid Tumors or Relapsed/Refractory Lymphoma
Betta Pharmaceuticals Co., Ltd.
NCT06349408 RECRUITING IBI3001 in Participants With Unresectable, Locally Advanced or Metastatic Solid Tumors
Innovent Biologics (Suzhou) Co. Ltd.
NCT05789602 RECRUITING A Study of BPI-460372 in Advanced Solid Tumor Patients
Betta Pharmaceuticals Co., Ltd.
NCT03791112 ACTIVE NOT RECRUITING A Phase I Study of BPI-16350 in Patients with Advanced Solid Tumor
Betta Pharmaceuticals Co., Ltd.
NCT06772415 RECRUITING A Study to Investigate Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy With GenSci122 in Participants With Advanced Solid Tumors
Changchun GeneScience Pharmaceutical Co., Ltd.
NCT06418061 RECRUITING Study of IBI3005 in Subjects With Unresectable, Locally Advanced or Metastatic Solid Tumors
Innovent Biologics (Suzhou) Co. Ltd.
NCT06299124 ACTIVE NOT RECRUITING A Phase I Study of RGT-419B in Patients With HR-Positive, HER2-Negative Advanced Breast Cancer or Other Solid Tumors
Regor Pharmaceuticals Inc.
NCT06782425 RECRUITING Treating Claudin18.2-positive Advanced Solid Tumors with XKDCT225(Targeting Claudin18.2-CAR-T)
Shenzhen Celconta Life Science Co., Ltd.
NCT06761651 RECRUITING A Study of TAVO412 in Patients with Cancer (TAVO412)
Tavotek Biotherapeutics
NCT06779045 NOT YET RECRUITING A Study of AK-1286 in Patients With Advanced Solid Tumors
Shanghai YingLi Pharmaceutical Co. Ltd.
NCT06770764 RECRUITING Dose Escalation and Expansion Study Evaluating ODC-IL2 in Adult Patients With Advanced or Metastatic Solid Tumors
Trutino Biosciences Inc.
NCT06764836 RECRUITING A Study of IMM2510 + IMM27M Combination Therapy in Patients With Advanced Solid Tumors
ImmuneOnco Biopharmaceuticals (Shanghai) Inc.
NCT06763159 RECRUITING A Study of HS-20124 in Patients with Advanced Solid Tumors
Hansoh BioMedical R&D Company
NCT06686745 RECRUITING Study of SIM0508 Alone and in Combination in Patients With Advanced Solid Tumors
Jiangsu Simcere Pharmaceutical Co., Ltd.
NCT06760117 RECRUITING UGT1A1 Genotype-drien Phase I Study of Irinotecan in VIT Regimen for the Treatment of Pediatric R/R Solid Tumors
Sun Yat-sen University
NCT06755242 NOT YET RECRUITING A Study of GNC-077 in Patients With Locally Advanced or Metastatic Gastrointestinal Tumors and Other Solid Tumors
Sichuan Baili Pharmaceutical Co., Ltd.
NCT06752447 NOT YET RECRUITING A Phase I Study OfLNF2007 Monotherapy in Patients with Advanced Solid Tumors
Shandong New Time Pharmaceutical Co., LTD
NCT06404905 RECRUITING Clinical Trial of BT02 in Patients With Advanced Solid Tumors
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT05954091 NOT YET RECRUITING OH2 Administered by Intratumoral Injection
Binhui Biopharmaceutical Co., Ltd.
NCT06748872 NOT YET RECRUITING EPITOME-1015-I: a Study to Investigate the Safety and Tolerability of MDG1015 in Patients with Epithelial Ovarian Cancer, Gastroesophageal Adenocarcinoma, Round Cell Liposarcoma And/or Synovial Sarcoma
Medigene AG
NCT06332430 RECRUITING Intratumoral CAN2109 in Subjects With Solid Tumors
Canwell Biotech Limited
NCT04576091 ACTIVE NOT RECRUITING Testing the Addition of an Anti-cancer Drug, BAY 1895344, With Radiation Therapy to the Usual Pembrolizumab Treatment for Recurrent Head and Neck Cancer
National Cancer Institute (NCI)
NCT06730659 RECRUITING A Clinical Study of CHT101 in CD70-Positive Advanced Solid Tumors
Tianjin Medical University Cancer Institute and Hospital
NCT06728189 RECRUITING A Clinical Research About CD70-targeted CAR-NKT Cells Therapy in Subjects with Advanced Malignant Solid Tumors
Peking University Cancer Hospital & Institute
NCT06726564 RECRUITING A Study of MT027 in Patients with Pleural Malignant Tumors
Suzhou Maximum Bio-tech Co., Ltd.
NCT06723964 ACTIVE NOT RECRUITING A Study of AP505 Injection in Patients With Advanced Malignant Solid Tumors
AP Biosciences Inc.
NCT06426680 RECRUITING A Study of the ILB-3101 in Patients with Advanced Solid Tumors
Innolake Biopharm
NCT04104607 RECRUITING The Bispecific PSMAxCD3 Antibody CC-1 in Patients with Castration Resistant Prostate Carcinoma
University Hospital Tuebingen
NCT06302062 RECRUITING Phase I Clinical Study of Tumor-associated Lymph Node T Cell Therapy for Advanced Solid Tumors
Guangzhou FineImmune Biotechnology Co., LTD.
NCT06710821 NOT YET RECRUITING Irinotecan Liposomes Combined with Temozolomide and Vincristine in the Treatment of Pediatric Patients with Solid Tumors
Yizhuo Zhang
NCT05667194 RECRUITING Phase 1 Trial of KH617
Sichuan Honghe Biotechnology Co., Ltd.
NCT05302037 RECRUITING Allogeneic NKG2DL-targeting CAR γδ T Cells (CTM-N2D) in Advanced Cancers (ANGELICA)
CytoMed Therapeutics Pte Ltd
NCT03842085 RECRUITING Phase I Clinical Study of MBS301 in Treatment of HER2 Positive Recurrent or Metastatic Malignant Solid Tumor
Beijing Mabworks Biotech Co., Ltd.
NCT06084286 RECRUITING Dual-targeting CLDN18.2 and PD-L1 CAR-T for Patients with CLDN18.2-positive Advanced Solid Tumors
Sichuan University
NCT06158477 RECRUITING A Clinical Trial Evaluating JYP0035 Capsule Monotherapy in Patients With Advanced Solid Tumors
Chengdu JOYO pharma Co., Ltd.
NCT06026254 ACTIVE NOT RECRUITING A Rollover Study for Subjects Who Completed Participation in IMSA101-101 Trial
ImmuneSensor Therapeutics Inc.
NCT06169579 ENROLLING BY INVITATION An Open-label, Phase 1 Study to Determine the Maximum Tolerated Dose of ND-003 in Patients With Advanced Solid Cancers
Shenzhen NewDEL Biotech, Co., Ltd
NCT05382325 ACTIVE NOT RECRUITING A Study of MK-1484 as Monotherapy and in Combination With Pembrolizumab (MK-3475) In Advanced or Metastatic Solid Tumors (MK-1484-001)
Merck Sharp & Dohme LLC
NCT05463952 ACTIVE NOT RECRUITING A Study to Learn About the Vepdegestrant (ARV-471, PF-07850327) in People With ER+/HER2- Locally Advanced or Metastatic Breast Cancer (BC)
Pfizer
NCT05156203 RECRUITING Safety and Tolerability Study for T-1301 Capsules to Treat Advanced Solid Tumors
Taivex Therapeutics Corporation
NCT05278546 ACTIVE NOT RECRUITING A Study of ILB2109 in Patients With Advanced Solid Malignancies
Innolake Biopharm
NCT03907527 ACTIVE NOT RECRUITING Modified Immune Cells (Autologous CAR T Cells) in Treating Patients with Advanced, Recurrent Platinum Resistant Ovarian, Fallopian Tube or Primary Peritoneal Cancer
Precigen, Inc
NCT05983523 RECRUITING A Study of PEP07 (Checkpoint Kinase 1 Inhibitor) in Patients with Advanced or Metastatic Solid Tumors
PharmaEngine
NCT06652529 NOT YET RECRUITING Phase 1 Dose Escalation and Expansion to Evaluate AROG4-01 in Patients With Advanced Solid Tumors
Aromics Therapeutics
NCT06190886 RECRUITING A First-in-human (FIH), Phase I Study of PTX-912 in Patients with Locally Advanced/Metastatic Solid Tumors
Proviva Therapeutics, Inc.
NCT04511871 ACTIVE NOT RECRUITING A Phase I Trial of CCT303-406 in Patients With Relapsed or Refractory HER2 Positive Solid Tumors
Shanghai PerHum Therapeutics Co., Ltd.
NCT05772455 RECRUITING A Study of XZB-0004 in Patients With Solid Tumors
Xuanzhu Biopharmaceutical Co., Ltd.
NCT05548634 ACTIVE NOT RECRUITING A Study of TAVO412 in Patients with Cancer
Tavotek Biotherapeutics
NCT05159440 ACTIVE NOT RECRUITING First in Human Study of TORL-2-307-MAB in Participants With Advanced Cancer
TORL Biotherapeutics, LLC
NCT04093466 RECRUITING A Phase 1 Study of CX1003 (Kanitinib) in Patients with Advanced Solid Tumors
Beijing Konruns Pharmaceutical Co., Ltd.
NCT04387916 RECRUITING A Study of KC1036 in Patients with Advanced Solid Tumors
Beijing Konruns Pharmaceutical Co., Ltd.
NCT05215574 ACTIVE NOT RECRUITING Study of NGM831 as Monotherapy and in Combination With Pembrolizumab or Pembrolizumab and NGM438 in Advanced or Metastatic Solid Tumors
NGM Biopharmaceuticals, Inc
NCT06632574 RECRUITING A Clinical Study of Paclitaxel Cationic Liposomes for the Treatment of Patients With Advanced Solid Tumors
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
NCT02521844 ACTIVE NOT RECRUITING A Study to Evaluate the Safety and Tolerability of ETC-1922159 as a Single Agent and in Combination With Pembrolizumab in Advanced Solid Tumours
EDDC (Experimental Drug Development Centre), A*STAR Research Entities
NCT06160752 RECRUITING Safety and Anti-Tumor Activity of TYRA-200 in Advanced Cholangiocarcinoma With Activating FGFR2 Gene Alterations
Tyra Biosciences, Inc
NCT03603951 ACTIVE NOT RECRUITING A Phase 1 Study of SHR2554 in Subjects With Relapsed or Refractory Mature Lymphoid Neoplasms
Jiangsu HengRui Medicine Co., Ltd.
NCT06621615 NOT YET RECRUITING Clinical Study of CVL006 Injection in Advanced Solid Tumors
Convalife (Shanghai) Co., Ltd.
NCT03546426 ACTIVE NOT RECRUITING Pembrolizumab Plus Autologous Dendritic Cell Vaccine in Patients with PD-L1 Negative Advanced Mesothelioma Who Have Failed Prior Therapies
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
NCT06614751 NOT YET RECRUITING A PARG Inhibitor DAT-2645 Monotherapy in Patients with Advanced/Metastatic Solid Tumors Harboring BRCA1/2 Loss of Function Alterations And/or Other Defects in the DDR Pathway
Danatlas Pharmaceuticals Co., Ltd
NCT06615193 RECRUITING A Study of HDM2005 in Patients With Relapsed/Refractory B-cell Lymphoma and Advanced Solid Tumor
Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.
NCT06614686 RECRUITING U87 CAR-T in Patients With Advanced Head and Neck Tumors
Shanghai Unicar-Therapy Bio-medicine Technology Co.,Ltd
NCT04999761 RECRUITING AB122 Platform Study
Taiho Pharmaceutical Co., Ltd.
NCT06259552 RECRUITING A Study of SPX-303, a Bispecific Antibody Targeting LILRB2 and PD-L1 in Patients With Solid Tumors
SparX Biotech(Jiangsu) Co., Ltd.
NCT06592417 RECRUITING To Evaluate the Phase I Clinical Study of JSKN016 in Chinese Patients With Advanced Malignant Solid Tumors
Jiangsu Alphamab Biopharmaceuticals Co., Ltd
NCT05773937 RECRUITING A Clinical Study of 9MW2821 in Advanced Malignant Solid Tumors
Mabwell (Shanghai) Bioscience Co., Ltd.
NCT04811703 RECRUITING Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) Associated With Systemic Chemotherapy in Women With Advanced Ovarian Cancer
Hospices Civils de Lyon
NCT06389526 NOT YET RECRUITING A Study of CHS-1000 in Participants With Advanced or Metastatic Solid Tumors
Coherus Oncology, Inc.
NCT03891706 RECRUITING Individualized Tumor Specific TCR- T Cells in the Treatment of Advanced Solid Tumors
Guangzhou FineImmune Biotechnology Co., LTD.
NCT06598735 NOT YET RECRUITING A Clinical Study of the Safety, Tolerability, Pharmacokinetics, and Initial Efficacy of HRS-4508 Monotherapy in Patients With Advanced or Metastatic Solid Tumors
Jiangsu HengRui Medicine Co., Ltd.
NCT06594874 NOT YET RECRUITING A Phase Ib Study of HS-10370 in Addition to Other Anti-cancer Therapies in Participants with KRAS G12C Mutation Advanced Solid Tumors
Jiangsu Hansoh Pharmaceutical Co., Ltd.
NCT06589401 RECRUITING Oral Paclitaxel for Patients with Advanced Solid Tumors
InnoUp Farma S.L.
NCT01883297 ACTIVE NOT RECRUITING "Re-Stimulated" TILs and IL-2 Therapy for Platinum Resistant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
University Health Network, Toronto
NCT04928612 RECRUITING A Study of CBP-1018 in Patients With Advanced Solid Tumors
Coherent Biopharma (Suzhou) Co., Ltd.
NCT04740398 RECRUITING A Study of CBP-1008 in Patients With Advanced Solid Tumor
Coherent Biopharma (Suzhou) Co., Ltd.
NCT06404281 RECRUITING γδ T-PD-1 Ab Cells in the Treatment of Advanced Solid Tumors
Changzhou No.2 People's Hospital
NCT05351502 RECRUITING A Study to Assess the Safety and Efficacy of Nitric Oxide Injection Into Unresectable Solid Primary or Metastatic Tumors
Beyond Air Inc.
NCT06558175 NOT YET RECRUITING Reirradiation Dose Escalation in Thoracic Cancers
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
NCT06553846 NOT YET RECRUITING A Clinial Trial of Lutetium [177Lu]-FAP-75 for the Treatment of Patients With Advanced Solid Tumors
Fudan University
NCT05244551 RECRUITING A Study to Assess Safety, Tolerability, and Pharmacokinetics of ABSK061 in Patients With Advanced Solid Tumors
Abbisko Therapeutics Co, Ltd
NCT06548672 RECRUITING A Study to Assess the Safety, Pharmacokinetics, and Antitumor Activity of BC3195 in Patients With Advanced or Metastatic Cancer
Biocity Biopharmaceutics Co., Ltd.
NCT06544720 RECRUITING SCG142 TCR-T Cells for Human Papillomavirus-Associated Carcinomas
The Affiliated Hospital of Qingdao University
NCT06452160 RECRUITING A Study of BGC515 Capsules in Subjects With Advanced Solid Tumors
BridGene Biosciences Inc.
NCT05266612 RECRUITING Phase I Study VG2025 as a Single Agent and in Combination Therapy With Nivolumab in Subjects With Advanced Malignant Solid Tumors
Virogin Biotech Canada Ltd
NCT06364501 NOT YET RECRUITING Phase 1 Trial of KH801
Beijing Kanghong Biopharmaceutical Co., Ltd.
NCT06274437 RECRUITING A Study of BND-35 in Participants With Advanced Solid Tumors
Biond Biologics
NCT06536400 RECRUITING Phase I Study of HSK42360 in Solid Tumors With BRAF V600 Mutation
Haisco Pharmaceutical Group Co., Ltd.
NCT06271252 RECRUITING A Study to Evaluate the Safety, PK/PD of (OriCAR-017) in Subjects With RR/MM - RIGEL Study
OriCell Therapeutics Co., Ltd.
NCT05076552 ACTIVE NOT RECRUITING A Study to Assess the Safety, Pharmacokinetics, and Antitumor Activity of Oral TACH101 in Participants With Advanced or Metastatic Cancer
Tachyon Therapeutics, Inc.
NCT05474859 NOT YET RECRUITING Subjects With Advanced or Metastatic Solid Tumor Malignancies
Xenthera, Inc.
NCT06530082 NOT YET RECRUITING A Single Arm Clinical Study of Dendritic Cell Vaccine Loaded With Circular RNA Encoding Cryptic Peptide for Patients With HER2-negative Advanced Breast Cancer
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
NCT06257680 RECRUITING A Phase I Study on ReT01 ACT for the Treatment of Advanced Solid Tumors
Aeonvital Biomedicine
NCT06528249 NOT YET RECRUITING Safety, Tolerability and Preliminary Efficacy of Erythrocyte-αPD-1 Conjugate in Patients With Advanced Malignancies
Zhejiang Provincial People's Hospital
NCT06386705 RECRUITING TSN084 Treating Patients With Advanced Malignant Tumors
Tyligand Bioscience (Shanghai) Limited
NCT06514651 RECRUITING MAQ-001 in Patients With Advanced Solid Tumors
MabQuest SA
NCT05878691 ACTIVE NOT RECRUITING A Study of GRC 54276 in Participants With Advanced Solid Tumors and Lymphomas.
Glenmark Specialty S.A.
NCT05731752 ACTIVE NOT RECRUITING Study on the Tolerability and Pharmacokinetics of HX009 in Patients With Advanced Solid Tumors
Hangzhou Hanx Biopharmaceuticals, Ltd.
NCT06332170 RECRUITING ARTEMIS-101: A Study of HS-20093 Combinations in Patients With Advanced Solid Tumors
Hansoh BioMedical R&D Company
NCT06336707 RECRUITING HS-20089 Combination Treatment in Subjects With Advanced Solid Tumors
Hansoh BioMedical R&D Company
NCT05979155 RECRUITING A Study of NWY001 in Subjects With Advanced Solid Tumors
Chipscreen Biosciences, Ltd.
NCT06501183 RECRUITING Anti-CDH17 CAR-T Cell Injection in Patients With CDH17-positive Advanced Malignant Solid Tumors
Shanghai Pudong Hospital
NCT05620862 ACTIVE NOT RECRUITING Phase I Dose Escalation and Pharmacokinetics Clinical Trial of Mitoxantrone Hydrochloride Liposome in Children With Relapsed and Refractory Lymphoma and Solid Tumors
Sun Yat-sen University
NCT06329206 RECRUITING A Phase Ia/Ib Study of GH2616 Tablet in Subjects With Advanced Solid Tumors
Suzhou Genhouse Bio Co., Ltd.
NCT05010694 ACTIVE NOT RECRUITING GH35 Tablets for Advanced Solid Tumors: A Study on Safety and Early Results
Suzhou Genhouse Bio Co., Ltd.
NCT06477614 RECRUITING Anti-cancer DC Cell Vaccination to Treat Solid Tumors
Second Affiliated Hospital of Guangzhou Medical University
NCT05830045 RECRUITING A Phase I Study of QLP2117 in Subjects With Advanced Solid Tumors
Qilu Pharmaceutical Co., Ltd.
NCT06195293 RECRUITING Anti-cancer Neoantigen Polypeptide Vaccine to Treat Solid Tumors
Second Affiliated Hospital of Guangzhou Medical University
NCT04952272 RECRUITING Intratumor CpG-ODN Injection Boosters Immune Killing Against in Situ Tumor Antigen Release for Advanced Solid Tumors
Second Affiliated Hospital of Guangzhou Medical University
NCT06195384 RECRUITING Anti-cancer Neoantigen mRNA Vaccine to Treat Solid Tumors
Second Affiliated Hospital of Guangzhou Medical University
NCT06196294 RECRUITING GPC3/Mesothelin-CAR-γδT Cells Against Cancers
Second Affiliated Hospital of Guangzhou Medical University
NCT05300438 ACTIVE NOT RECRUITING Phase I Study of TSN084 in Patients With Advanced Malignant Tumors.
Tyligand Bioscience (Shanghai) Limited
NCT04842812 RECRUITING Engineered TILs/CAR-TILs to Treat Advanced Solid Tumors
Second Affiliated Hospital of Guangzhou Medical University
NCT05779917 RECRUITING Mesothelin/GPC3/GUCY2C-CAR-T Cells Against Cancers
Second Affiliated Hospital of Guangzhou Medical University
NCT05410717 RECRUITING CLDN6/GPC3/Mesothelin/AXL-CAR-NK Cell Therapy for Advanced Solid Tumors
Second Affiliated Hospital of Guangzhou Medical University
NCT06473948 NOT YET RECRUITING To Assess the Effects of Single Dose of JMKX001899 on QTc Interval in Healthy Subjects
Jemincare
NCT03778814 RECRUITING TCR-T Cell Immunotherapy of Lung Cancer and Other Solid Tumors
Second Affiliated Hospital of Guangzhou Medical University
NCT03198052 RECRUITING GPC3/Mesothelin/Claudin18.2/GUCY2C/B7-H3/PSCA/PSMA/MUC1/TGFβ/HER2/Lewis-Y/AXL/EGFR-CAR-T Cells Against Cancers
Second Affiliated Hospital of Guangzhou Medical University
NCT03530397 ACTIVE NOT RECRUITING A Study to Evaluate MEDI5752 in Subjects With Advanced Solid Tumors
MedImmune LLC
NCT05819684 RECRUITING A Study of SHR-4602 in Subjects With Advanced Malignant Solid Tumors
Suzhou Suncadia Biopharmaceuticals Co., Ltd.
NCT06466265 RECRUITING Study of DNP002 in Patients With Solid Tumors
Kumho HT Inc.
NCT06445517 RECRUITING Study Evaluating ISM8207 in Participants With Advanced Solid Tumors and Relapsed/Refractory B-Cell Lymphoma
InSilico Medicine Hong Kong Limited
NCT06399419 RECRUITING CBM588 Capsules in Combination With Nivolumab and Ipilimumab for the Treatment of Advanced Stage Kidney Cancer
Osel, Inc.
NCT06433726 RECRUITING A Phase l Study of By101921, an Oral PARP7 Inhibitor, in Patients With Advanced Solid Tumors
Chengdu Baiyu Pharmaceutical Co., Ltd.
NCT06421610 RECRUITING OPC5: Pressurized IntraThoracic Aerosol Chemotherapy (PITAC) in Patients With Malignant Pleural Effusion.
Odense University Hospital
NCT05564858 RECRUITING A Study of FDA022-BB05 in Subjects With Advanced Solid Malignant Tumors
Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd.
NCT06418113 RECRUITING Neoadjuvant Radio-chemotherapy Safety Pilot Study in Patients With Glioblastoma
Hospital San Carlos, Madrid
NCT06415500 NOT YET RECRUITING A Study on the Safety and Preliminary Efficacy of NK042 in the Treatment of Malignant Ascites
Anhui Provincial Hospital
NCT06415903 NOT YET RECRUITING A Clinical Trial of TQB3117 Tablets in Patients With Advanced Malignant Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT05751356 RECRUITING TR128 in Patients With Advanced Solid Tumors
Tarapeutics Science Inc.
NCT05650580 RECRUITING TR115 in Patients With Relapsed / Refractory Non-Hodgkin's Lymphoma or Advanced Solid Tumors
Tarapeutics Science Inc.
NCT05649345 RECRUITING TR64 in Patients With Advanced Solid Tumors
Tarapeutics Science Inc.
NCT06410092 RECRUITING Study in Patients With Advanced Solid Malignancies to Evaluate the Safety of FTL001
Sound Biopharmaceuticals Ltd.
NCT06403735 RECRUITING A Phase I Clinical Study of QLC1101 in Patients With Advanced Solid Tumors
Qilu Pharmaceutical Co., Ltd.
NCT06086522 RECRUITING Trial to Evaluate Safety, PD & PK of IV Study Drug, QN-302, in Pts w/ Advanced or Metastatic Solid Tumors
Qualigen Theraputics, Inc.
NCT05868174 RECRUITING Combination of 177Lu-TLX250 and Peposertib in Patients With Carbonic Anhydrase IX -Expressing Solid Tumors
Telix Pharmaceuticals (Innovations) Pty Limited
NCT06394622 RECRUITING A Clinical Research About CD70-targeted CAR-NKT Cells Therapy Advanced Malignant Solid Tumors
Fudan University
NCT05909241 RECRUITING A Study of BA1202 in Patients With Advanced Solid Tumors
Shandong Boan Biotechnology Co., Ltd
NCT06383507 NOT YET RECRUITING A Clinical Study of Anti-CD70 UCAR-T in Relapsed or Refractory Solid Tumors
Zhejiang University
NCT06374173 RECRUITING A Phase 1 Study to Evaluate TGI-6 in Subjects With Locally Advanced/Metastatic Solid Tumors
Hefei TG ImmunoPharma Co., Ltd.
NCT06358053 NOT YET RECRUITING CRTE7A2-01 TCR-T Cells for HPV-16 Positive Advanced Cancers
Corregene Biotechnology Co., Ltd
NCT05263479 RECRUITING A Study of HS-20089 in Patients With Advanced Solid Tumors
Shanghai Hansoh Biomedical Co., Ltd
NCT06342336 RECRUITING HS-IT101 Injection in the Treatment of Advanced Solid Tumors
Qingdao Sino-Cell Biomedicine Co., Ltd.
NCT06223256 RECRUITING A Study of NBL-028 in Patients With Advanced Solid Tumors
NovaRock Biotherapeutics, Ltd
NCT06240546 RECRUITING First-in-Human Study of LPM6690176 in Patients With Advanced Solid Tumors.
Luye Pharma Group Ltd.
NCT04965077 RECRUITING Treatment of Advanced and Metastatic Solid Tumors With MIL97
Beijing Mabworks Biotech Co., Ltd.
NCT06307249 RECRUITING Precision Therapy for Solid Tumors: Synergistic CDK4/6 Inhibition and Anti-VEGF Targeting LncRNA
Lebanese University
NCT06101082 RECRUITING A Clinical Study Evaluating the Safety and Efficacy of Anti-HER2-CAR-T Cells Injection in Patients With Solid Tumors
China Medical University, China
NCT05877664 RECRUITING Study of ZG0895.HCl in Patients With Advanced Solid Tumors
Suzhou Zelgen Biopharmaceuticals Co.,Ltd
NCT06205082 ENROLLING BY INVITATION A Phase I Clinical Trial to Evaluate LIT-00814 Tablets in Patients With Advanced Solid Tumor
LittDD Medicines Ltd
NCT06277804 NOT YET RECRUITING A Phase I Study of LTC004 Combin With FC in Patients With Advanced/Metastatic Malignancies Tumor
Letolab
NCT04282044 RECRUITING Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid Malignancies
BioEclipse Therapeutics
NCT06246071 RECRUITING A Study of TYK-00540 in Adult Patients With Solid Tumors
TYK Medicines, Inc
NCT06037317 RECRUITING A Study of SY-3505 in Patients With Advanced LTK Fusion-Positive Solid Tumors
Shouyao Holdings (Beijing) Co. LTD
NCT05952947 RECRUITING HRYZ-T101 Injection for HPV18 Positive Solid Tumor
HRYZ Biotech Co.
NCT06225856 RECRUITING An Open-Label, Multicenter, Phase I Study to Evaluate the Safety, Pharmacokinetics and Preliminary Efficacy of YY201 in Patients With Advanced Solid Tumors and Hematological Malignancies
Shanghai Yuyao Biotech Co., Ltd.
NCT06215950 RECRUITING A Clinical Research About CD70-targeted CAR-T in the Treatment of CD70-positive Advanced/Metastatic Gynecologic Cancer
Chongqing Precision Biotech Co., Ltd
NCT06211647 RECRUITING A Clinical Study of [177Lu]Lu-XT117 Injection in Patients With Advanced Solid Tumors
Ruimin Wang
NCT06209385 RECRUITING A Phase 1 Study of YZJ-5053 Tablets in Participants With Advanced Solid Tumors
Shanghai Haiyan Pharmaceutical Technology Co., Ltd.
NCT06166888 RECRUITING A Study of AK131 in Patients With Advanced Solid Tumors
Akeso
NCT05582590 NOT YET RECRUITING Autologous T Cells Targeting HPV16 HPV18 & Survivin in Patients With R/R HPV-related Oropharyngeal Cancers
NexImmune Inc.
NCT06197139 RECRUITING A Clinical Study of [177Lu]Lu-XT117 Injection in Patients With Advanced Solid Tumors
Xinlu Wang
NCT06193993 ACTIVE NOT RECRUITING Effect of Low-dose 500 mg Abiraterone Acetate in Treatment of Metastatic Prostate Cancer Patients
National University Hospital, Singapore
NCT06170294 RECRUITING MAGE-A4-directed TCR-T in the Treatment Amongst Subjects With Advanced Solid Tumors
Peking University
NCT06166472 NOT YET RECRUITING A Study to Evaluate the Safety, Tolerance, Pharmacokinetics, and Preliminary Antineoplastic Activity of AK132 in Advanced Malignant Solid Tumor
Akeso
NCT05940896 RECRUITING RC48-ADC Combined With Radiotherapy in the Treatment of Locally Advanced Solid Tumors With HER2 Expression
RemeGen Co., Ltd.
NCT06134960 NOT YET RECRUITING NKG2D/CLDN18.21 CAR-T(KD-496) in the Treatment of Advanced NKG2DL+/CLDN18.2+ Solid Tumor
Peking University
NCT06134531 NOT YET RECRUITING First-In-Human Study of Bispecific Antibody MR001 In Subjects With Advanced Solid Tumors
Nanfang Hospital, Southern Medical University
NCT06131216 NOT YET RECRUITING Phase I Study of SHR-2022 Injection in the Treatment of Patients With Advanced Malignant Tumors
Suzhou Suncadia Biopharmaceuticals Co., Ltd.
NCT06126406 RECRUITING Clinical Study of CEA Targeting Chimeric Antigen Receptor T Lymphocytes(CAR-T) for CEA Positive Advanced Malignant Solid Tumors
Chongqing Precision Biotech Co., Ltd
NCT06121557 RECRUITING Phase I Study of Autologous Tumor-Draining Lymph Node-Derived Lymphocytes for Advanced HER2-Negative Breast Cancer
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
NCT06121570 RECRUITING Phase I Study of Autologous Tumor-Draining Lymph Node-Derived Lymphocytes as Neoadjuvant Therapy for HER2-Negative Breast Cancer
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
NCT06010875 RECRUITING A Clinical Research About CD70-targeted CAR-T in the Treatment of CD70-positive Advanced/Metastatic Solid Tumors
Chongqing Precision Biotech Co., Ltd
NCT06010862 RECRUITING Clinical Study of CEA-targeted CAR-T Therapy for CEA-positive Advanced/Metastatic Malignant Solid Tumors
Chongqing Precision Biotech Co., Ltd
NCT05866692 RECRUITING A Study of TY-2699a in Patients With Locally Advanced or Metastatic Solid Tumors
TYK Medicines, Inc
NCT05895825 RECRUITING A Study of EOC237 in Patients With Advanced Solid Tumor
Shanghai Yiteng Jingang Bio-pharmaceutical Technology Co., Ltd
NCT06093698 NOT YET RECRUITING An Exploratory Study of A-337 in the Management of Malignant Solid Dose Escalation and Expansion Phases
ITabMed Co., Ltd.
NCT05621486 ACTIVE NOT RECRUITING A Clinical Study to Evaluate B4T2-001 CAR T Cells in the Treatment of Advanced Solid Tumors
Shanghai East Hospital
NCT06072989 RECRUITING Repeat Intravenous Infusions of B4T2-001 CAR-T Without Lymphodepleting Chemotherapy for Solid Tumors
Shanghai East Hospital
NCT02193503 ACTIVE NOT RECRUITING MVX-ONCO-1 in Patients With Solid Tumor
Maxivax SA
NCT06043466 RECRUITING A Clinical Trial Targeting CEA Chimeric Antigen Receptor T (CAR-T) for CEA Positive Advanced Malignant Solid Tumors
Chongqing Precision Biotech Co., Ltd
NCT06019702 RECRUITING Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen Alone in Subjects With Advanced Digestive System Neoplasms
Sir Run Run Shaw Hospital
NCT06026774 RECRUITING Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen in Subjects With Resected Digestive System Neoplasms
Sir Run Run Shaw Hospital
NCT06026800 RECRUITING Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen in Combination With Standard First-line Treatment in Subjects With Advanced Digestive System Neoplasms
Sir Run Run Shaw Hospital
NCT06027346 RECRUITING A Study of Bio-008 in Subjects With Advanced or Metastatic Solid Tumours
Shijiazhuang Yiling Pharmaceutical Co. Ltd
NCT05631886 RECRUITING Combination of CAR-DC Vaccine and ICIs in Malignant Tumors
Chinese PLA General Hospital
NCT05982080 RECRUITING A Study to Investigate FP002 in Subjects With Advanced Malignancies
Guangdong Fapon Biopharma Inc.
NCT05788107 NOT YET RECRUITING Evaluate the Safety, Tolerability, and Pharmacokinetic Characteristics of HLX51 in Patients With Solid Tumor or Lymphoma
Shanghai Henlius Biotech
NCT05886374 RECRUITING A Study of HMPL-415S1 in Patients With Advanced Malignant Solid Tumors
Hutchmed
NCT05940116 NOT YET RECRUITING A Phase I Clinical Study of HS-20117 in Participants With Advanced Solid Tumors
Hansoh BioMedical R&D Company
NCT05933668 NOT YET RECRUITING Mutant KRAS G12V-specific TCR Transduced T Cell Therapy for Advanced Solid Tumor
Peking University
NCT05924906 NOT YET RECRUITING A Dose Escalation and Expansion Study of NB002 in Participants With Advanced or Metastatic Solid Tumors
Suzhou Neologics Bioscience Co., Ltd.
NCT05911464 RECRUITING A Phase I Study of HS-10386 in Participants With Advanced Solid Tumors
Jiangsu Hansoh Pharmaceutical Co., Ltd.
NCT05823285 RECRUITING A Study Evaluates the Safety, Pharmacokinetics, Immunogenicity and Efficacy of QLS31903 in Advanced Solid Tumor Patients
Qilu Pharmaceutical Co., Ltd.
NCT05361954 NOT YET RECRUITING Study to Assess the Safety and Preliminary Efficacy of STI-1386 Oncolytic Virus in Relapsed or Refractory Solid Tumors
Sorrento Therapeutics, Inc.
NCT05804864 NOT YET RECRUITING A Study of KM501 in Patients With Solid Tumors
Xuanzhu Biopharmaceutical Co., Ltd.
NCT05783089 NOT YET RECRUITING MSLN-targeted CAR-T Cells in Solid Tumors.
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT05766527 NOT YET RECRUITING A Study of KM602 in Patients With Advanced Solid Tumors
Xuanzhu Biopharmaceutical Co., Ltd.
NCT05528055 RECRUITING A Study to Investigate the Safety and Tolerability of SCR-6920 Capsule in Patients With Advanced Malignant Tumors
Jiangsu Simcere Pharmaceutical Co., Ltd.
NCT02477878 ACTIVE NOT RECRUITING Study of Gene Modified Donor T Cell Infusion in Patients With Recurrent Disease After Allogeneic Transplant
Bellicum Pharmaceuticals
NCT05392699 RECRUITING ABOD2011 in Patients With Advanced Solid Tumors Progressed After Standard Systemic Therapy
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NCT05320874 NOT YET RECRUITING A Study of KM257 in Patients With Advanced HER2-positive or Expressing Solid Tumors.
Xuanzhu Biopharmaceutical Co., Ltd.
NCT05172310 RECRUITING PET Imaging of Solid Tumors by a Novel Tracer, 68Ga-FAPI
Karolinska University Hospital
NCT07596693 RECRUITING KXV01 Injection in Patients With Advanced Solid Tumor (Including Osteosarcoma and Sarcoma)
TCRx Therapeutics Co.Ltd
NCT07596381 NOT YET RECRUITING FAK Inhibitor in Patients With Advanced Solid Tumors
InxMed (Shanghai) Co., Ltd.
NCT07593144 NOT YET RECRUITING A Single-Arm, Open-Label Phase Ia/Ib Clinical Trial Evaluating the Safety, Tolerability, Pharmacokinetic Profile, and Preliminary Efficacy of FS-207 in Patients With Advanced Solid Tumors With High Microsatellite Instability (MSI-H)
Foresight Therapeutics (Hefei) Co., Ltd.
NCT07589205 RECRUITING Study of IBI3028 in Participants With Locally Advanced, Unresectable, or Metastatic Solid Tumors
Innovent Biopharmaceutical Technology (Hangzhou) Co., LTD.
NCT07591285 NOT YET RECRUITING A Study of SYS6051 in Subjects With Advanced Solid Tumors
CSPC Megalith Biopharmaceutical Co.,Ltd.
NCT07591155 NOT YET RECRUITING A Study of BL-ARC002 in Patients With Locally Advanced or Metastatic Solid Tumors
Sichuan Baili Pharmaceutical Co., Ltd.
NCT02797795 COMPLETED A Phase 1, Open-Label, Dose-Escalation Study of NEV801, Administered to Patients With Advanced Cancers
Neovia Oncology Ltd.
NCT05673460 COMPLETED A Clinical Study of Nemtabrutinib in Japanese Participants With Hematological Malignancies (MK-1026-002)
Merck Sharp & Dohme LLC
NCT04354246 COMPLETED COM902 (A TIGIT Inhibitor) in Subjects With Advanced Malignancies
Compugen Ltd
NCT05155332 SUSPENDED A Study to Test Different Doses of BI 1831169 Alone and in Combination With an Anti-PD-1 Antibody in People With Different Types of Advanced Cancer (Solid Tumors)
Boehringer Ingelheim
NCT05162755 COMPLETED S095029 as Monotherapy and in Combination With Sym021 in Patients With Advanced Solid Tumor Malignancies Followed by an Expansion Part With Triple Combinations in Patients With Metastatic Gastric or Colorectal Cancers
Institut de Recherches Internationales Servier
NCT05582850 TERMINATED DT-9081 Study in Participants With Advanced, Recurrent or Metastatic Solid Tumours
Domain Therapeutics SA
NCT02437227 COMPLETED Dose Escalation Study With Expansion to Evaluate Safety, Tolerability, Pharmacokinetics & Pharmacodynamics of CCT3833
Royal Marsden NHS Foundation Trust
NCT06568614 TERMINATED An Investigational Study of BG-89894 Tablets in Participants With Advanced Solid Tumors
BeOne Medicines
NCT06487858 TERMINATED A Study of BGB-R046 as Monotherapy and in Combination With Tislelizumab in Solid Tumors
BeOne Medicines
NCT05076396 COMPLETED PM14 Administered Intravenously to Patients With Advanced Solid Tumors
PharmaMar
NCT05549804 COMPLETED A Study of Intratumoral KL340399 in Patients With Advanced Solid Tumors
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.
NCT05387928 COMPLETED A Study of KL340399 in Patients With Advanced Solid Tumors
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.
NCT06573294 TERMINATED Trial to Assess the Safety and Antitumor Activity of GEN1057 in Malignant Solid Tumors
Genmab
NCT06091930 COMPLETED A Study to Test Different Doses of BI 765049 Alone and in Combination With Ezabenlimab in Asian People With Advanced Cancer (Solid Tumours) Positive for B7-H6
Boehringer Ingelheim
NCT01875601 COMPLETED NK White Blood Cells and Interleukin in Children and Young Adults With Advanced Solid Tumors
National Cancer Institute (NCI)
NCT05111353 COMPLETED Neoantigen Vaccines in Pancreatic Cancer in the Window Prior to Surgery
Washington University School of Medicine
NCT07159828 TERMINATED A Study to Assess AXN-2510 Treatment in Adult Patients With Advanced Solid Tumors
Axion Bio, Inc
NCT04380753 COMPLETED AMG 510 Ethnic Sensitivity Study (CodeBreaK 105).
Amgen
NCT03144466 TERMINATED A Study of Pembrolizumab And Platinum With Radiotherapy in Cervix Cancer
Royal Marsden NHS Foundation Trust
NCT05983133 TERMINATED A Study of PF-08046052/SGN-EGFRd2 in Advanced Solid Tumors
Seagen, a wholly owned subsidiary of Pfizer
NCT05824663 COMPLETED A Study Evaluating the Safety, Tolerance and Anti-tumor Activity of HBM1020 in Subjects With Advanced Solid Tumors
Harbour BioMed US, Inc.
NCT04457778 COMPLETED First in Human Study of M6223
EMD Serono Research & Development Institute, Inc.
NCT01445509 COMPLETED Dasatinib in Combination With Bevacizumab to Treat Advanced Solid Tumors
National Cancer Institute (NCI)
NCT05300048 TERMINATED Combination of Serabelisib and Insulin Suppressing Diet With or Without Nab-paclitaxel in Subjects With Advanced Solid Tumors With PIK3CA Mutations
Faeth Therapeutics
NCT02211755 COMPLETED Trial of the Combination of Bortezomib and Clofarabine in Adults With Relapsed Solid Tumors
National Cancer Institute (NCI)
NCT07554196 COMPLETED A Phase 1 Clinical Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of HH-101 in Patients With Advanced Solid Tumors
Huahui Health
NCT05085548 COMPLETED ProAgio in Previously Treated Advanced Pancreatic Cancer and Other Solid Tumor Malignancies
ProDa BioTech, LLC
NCT06104449 COMPLETED A Study of Opevesostat (MK-568)4 in Japanese Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-5684-005)
Merck Sharp & Dohme LLC
NCT05430360 TERMINATED Autologous Tumor-infiltrating Lymphocyte Injection (GT201) for the Treatment of Metastatic/Recurrent Advanced Solid Tumors
Grit Biotechnology
NCT02423057 COMPLETED Phase I Trial of 4'-Thio-2'-Deoxycytidine (TdCyd) in Patients With Advanced Solid Tumors
National Cancer Institute (NCI)
NCT01552434 TERMINATED Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign Disease
M.D. Anderson Cancer Center
NCT04868773 COMPLETED Study of Cabozantinib Plus TAS102 in mCRC as Salvage Therapy
University of California, Irvine
NCT06308263 COMPLETED Tuvusertib (M1774) Human Mass Balance and Absolute Bioavailability Study (DDRIVER Solid Tumors 303)
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
NCT05341349 TERMINATED Stereotactic Radiosurgery and Immune Checkpoint Inhibitors With NovoTTF-200M for the Treatment of Melanoma Brain Metastases
Emory University
NCT05036291 TERMINATED A Study of NB004 as Monotherapy or Combination Therapy in Patients With Advanced Solid Tumors
Ningbo Newbay Technology Development Co., Ltd
NCT06779851 TERMINATED A Study to Evaluate Safety and Tolerability of BPT567 in Patients With Advanced Solid Tumors
Bright Peak Therapeutics Inc
NCT05204147 SUSPENDED Actinium 225 Labeled Anti-CEA Antibody (Ac225-DOTA-M5A) for the Treatment of CEA Producing Advanced or Metastatic Cancers
City of Hope Medical Center
NCT05198349 TERMINATED First in Human Study of M1069 in Advanced Solid Tumors
EMD Serono Research & Development Institute, Inc.
NCT02379416 COMPLETED Combination Nilotinib and Paclitaxel in Adults With Relapsed Solid Tumors
National Cancer Institute (NCI)
NCT06741072 SUSPENDED BZLF1 Peptide Vaccine (OSU-2131) With QS-21 for the Prevention of Epstein-Barr Virus Related Cancer in Patients Awaiting Solid Organ Transplants
Ohio State University Comprehensive Cancer Center
NCT05022849 COMPLETED A Study of JNJ-75229414 for Metastatic Castration-resistant Prostate Cancer Participants
Janssen Research & Development, LLC
NCT03881488 COMPLETED Study of CTX-471 as a Monotherapy or in Combination With Pembrolizumab in Patients Post PD-1/PD-L1 Inhibitors in Metastatic or Locally Advanced Malignancies
Compass Therapeutics
NCT05607199 TERMINATED A First in Human Study of AUR 103 Calcium to Evaluate Safety, Pharmacokinetics and Pharmacodynamics
Aurigene Discovery Technologies Limited
NCT05861947 TERMINATED A Phase 1 Clinical Trial of AUR106 in Patients With Relapsed Advanced Malignancies
Aurigene Discovery Technologies Limited
NCT05605119 TERMINATED First in Human, Dose Escalation, Dose Expansion Study of AUR105
Aurigene Discovery Technologies Limited
NCT03317743 COMPLETED Study to Assess the Safety & Tolerability of NOV140101(IDX-1197) in Patients With Advanced Solid Tumors
Idience Co., Ltd.
NCT07529535 SUSPENDED A First-in-Human Study of ALK-N001 for Injection in Patients With Advanced Solid Tumors
Zhejiang Anglikang Pharmaceutical Co., Ltd.
NCT04241835 TERMINATED A Study to Compare the Blood Levels and Safety of Tazemetostat in Participants With Advanced Cancer and Moderate/Severe Liver Impairment to Participants With Advanced Cancer and Normal Liver Function
Epizyme, Inc.
NCT03114319 TERMINATED Dose Finding Study of TNO155 in Adult Patients With Advanced Solid Tumors
Novartis Pharmaceuticals
NCT01352962 COMPLETED Gemcitabine, Carboplatin, and Lenalidomide for Treatment of Advanced/Metastatic Urothelial Cancer and Other Solid Tumors
National Cancer Institute (NCI)
NCT01642017 TERMINATED Phase I Clinical and Pharmacokinetic Study of Pazopanib in a Population of Frail Elderly Patients According SIOG Criteria
Institut Claudius Regaud
NCT05639153 TERMINATED A Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of DR30303 in Patients With Advanced Solid Tumors
Zhejiang Doer Biologics Co., Ltd.
NCT03403049 COMPLETED Carbon Ion Radiation Therapy for Locally Advanced Pancreatic Cancer
Montefiore Medical Center
NCT05879627 TERMINATED To Evaluate the Safety, Tolerance and Pharmacokinetics of BAT8007 for Injection in Patients With Advanced Solid Tumors
Bio-Thera Solutions
NCT06130254 TERMINATED Phase Ib Trial of the KRAS G12C Inhibitor Adagrasib (MRTX849) in Combination With the PARP Inhibitor Olaparib in Patients With KRAS G12C Mutated Advanced Solid Tumors, With a Focus on Gynecological, Breast, Pancreatic and KEAP1 Mutated Non-small Cell Lung Cancers
M.D. Anderson Cancer Center
NCT04892017 TERMINATED Study of Inlexisertib (DCC-3116) in Participants With RAS/MAPK Pathway Mutant Solid Tumors
Deciphera Pharmaceuticals, LLC
NCT04931823 TERMINATED Dose Escalation and Dose Expansion Study of CPO-100 in Patients With Advanced Solid Tumors
Conjupro Biotherapeutics, Inc.
NCT06476548 COMPLETED Mindfulness-Based Ecological Momentary Intervention For Smoking Cessation Among Cancer Survivors
H. Lee Moffitt Cancer Center and Research Institute
NCT04050709 COMPLETED QUILT-3.064: PD-L1 t-haNK In Subjects With Locally Advanced Or Metastatic Solid Cancers
ImmunityBio, Inc.
NCT04303858 COMPLETED A Study to Evaluate Safety and Anti-Tumor Activity of Eciskafusp Alfa (RO7284755) Alone or in Combination With Atezolizumab in Participants With Advanced and/or Metastatic Solid Tumors
Hoffmann-La Roche
NCT03798626 COMPLETED Gevokizumab With Standard of Care Anti-cancer Therapies for Metastatic Colorectal, Gastroesophageal, and Renal Cancers
Novartis Pharmaceuticals
NCT05148325 COMPLETED Assessment of Safety ,Tolerance and Pharmacokinetics Clinical Efficacy With BAT4706 in Advanced Solid Tumors
Bio-Thera Solutions
NCT03449381 COMPLETED This Study Aims to Find the Best Dose of BI 907828 (Brigimadlin) in Patients With Different Types of Advanced Cancer (Solid Tumors)
Boehringer Ingelheim
NCT06110195 TERMINATED Study of Xevinapant With Radiation and Chemotherapy for Patients With Head and Neck Cancer
University of Chicago
NCT06188208 TERMINATED A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-130850 in Participants With Advanced Solid and Hematologic Tumors
Vividion Therapeutics, Inc.
NCT05848466 COMPLETED Assessment of Safety, Tolerability and Pharmacokinetics With BAT8010 for Injection in Advanced Malignant Solid Tumors Patients
Bio-Thera Solutions
NCT05933070 TERMINATED A Phase I Open-Label Dose Escalation Study of Intravenous INKmune In Patients With MDS or AML
Inmune Bio, Inc.
NCT02133625 COMPLETED A Study of Pioglitazone and Carboplatin in Patients With Advanced Solid Tumors
Dana-Farber Cancer Institute
NCT04234113 TERMINATED Study of Nanrilkefusp Alfa Alone and With Pembrolizumab in Adult Patients With Advanced/Metastatic Solid Tumors
SOTIO Biotech AG
NCT03568058 COMPLETED Personalized Immunotherapy in Adults With Advanced Cancers Immunotherapy in Adults With Advanced Cancers
Aaron Miller
NCT05727839 COMPLETED Study to Evaluate JCXH-211 as Monotherapy in Patients With Malignant Solid Tumors
Immorna Biotherapeutics, Inc.
NCT03420963 TERMINATED Donor Natural Killer Cells, Cyclophosphamide, and Etoposide in Treating Children and Young Adults With Relapsed or Refractory Solid Tumors
M.D. Anderson Cancer Center
NCT02215720 COMPLETED Temsirolimus and Cetuximab in Patients With Advanced or Metastatic Solid Tumors
Gustave Roussy, Cancer Campus, Grand Paris
NCT05394675 TERMINATED A Study of DS-9606a in Patients With Advanced Solid Tumors
Daiichi Sankyo
NCT05411133 COMPLETED Treatment of Cabotamig (ARB202) in Advanced Gastrointestinal Cancer Patients
Arbele Pty Ltd
NCT06136598 COMPLETED A Study of Opevesostat (MK-5684) in China Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC) (MK-5684-001)
Merck Sharp & Dohme LLC
NCT04423029 COMPLETED A Study of DF6002 Alone and in Combination With Nivolumab
Dragonfly Therapeutics
NCT04158336 COMPLETED A Study of Azenosertib (ZN-c3) in Participants With Solid Tumors
K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc
NCT02642809 COMPLETED Pembrolizumab With Locally Delivered Radiation Therapy for the Treatment of Metastatic Esophageal Cancers
Washington University School of Medicine
NCT06298357 COMPLETED Virtual Reality Gaming for Exercise and Mindfulness Among Pediatric Cancer Rehabilitation
University of Alabama at Birmingham
NCT06799533 TERMINATED A Study to Learn About the Study Medicine Called PF-08046031 in Advanced Melanoma and Other Solid Tumors
Pfizer
NCT06108479 COMPLETED Study of DF6215 in Patients With Advanced Solid Tumors
Dragonfly Therapeutics
NCT03258593 COMPLETED Durvalumab and Vicineum in Subjects With High-Grade Non-Muscle-Invasive Bladder Cancer Previously Treated With Bacillus Calmette-Guerin (BCG)
National Cancer Institute (NCI)
NCT06056024 COMPLETED A Study to Test How Well Different Doses of BI 3706674 Are Tolerated by People With Advanced Cancer in the Stomach and Oesophagus
Boehringer Ingelheim
NCT06894771 COMPLETED A Study of MK-4700 Alone or With Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors (MK-4700-001)
Merck Sharp & Dohme LLC
NCT01374620 COMPLETED Weekly Paclitaxel and Cyclophosphamide in Metronomic Administration : Dose Escalation Study of Weekly Paclitaxel
Centre Oscar Lambret
NCT06540066 TERMINATED A Study of BGB-B3227 Alone and in Combination With Tislelizumab in Participants With Advanced or Metastatic Solid Tumors
BeiGene
NCT05935098 TERMINATED BGB-A3055 Alone and in Combination With Tislelizumab in Participants With Solid Tumors
BeiGene
NCT01046487 COMPLETED Imatinib Mesylate And Cyclophosphamide In Metronomic Administration: Dose Escalation Study Of Imatinib Mesylate
Centre Oscar Lambret
NCT06391918 TERMINATED Phase 1 Study of GEN2 in Patients With Advanced Solid Tumors
GenVivo, Inc.
NCT03239145 COMPLETED Pembrolizumab (Anti-PD-1) and AMG386 (Angiopoietin-2 (Ang-2) in Patients With Advanced Solid Tumor
Dana-Farber Cancer Institute
NCT04261413 COMPLETED Phase Ia/Ib Study of RS-0139 in Patients With a Recurrent, Locally Advanced or Metastatic Solid Tumors
RS Arastirma Egitim Danismanlik Ilac Sanayi Ticaret A.S.
NCT05735366 COMPLETED A Phase 1 Study of SAIL66 in Patients With CLDN6-positive Locally Advanced or Metastatic Solid Tumors
Chugai Pharmaceutical
NCT02780128 TERMINATED Next Generation Personalized Neuroblastoma Therapy
Yael P Mosse
NCT02858869 COMPLETED Pembrolizumab and Stereotactic Radiosurgery for Melanoma or Non-Small Cell Lung Cancer Brain Metastases
Emory University
NCT04695327 COMPLETED TNFα and IL-2 Coding Oncolytic Adenovirus TILT-123 Monotherapy
TILT Biotherapeutics Ltd.
NCT05346484 TERMINATED A Study of CF33-hNIS (VAXINIA), an Oncolytic Virus, as Monotherapy or in Combination With Pembrolizumab in Adults With Metastatic or Advanced Solid Tumors
Imugene Limited
NCT06063317 TERMINATED A Study of onCARlytics (CF33-CD19) in Combination With Blinatumomab in Adults With Advanced or Metastatic Solid Tumors (OASIS)
Imugene Limited
NCT06287463 TERMINATED Study of DCC-3084 in Participants With Advanced Malignancies Driven by the Mitogen-Activated Protein Kinase (MAPK) Pathway
Deciphera Pharmaceuticals, LLC
NCT05999968 COMPLETED Abemaciclib Plus Darolutamide in Prostate Cancer That Has Spread After Initial Treatment
Eli Lilly and Company
NCT06625515 TERMINATED First-in-Human Study of ATX-559, an Oral Inhibitor of DHX9, in Patients With Advanced or Metastatic Solid Tumors, and Molecularly Defined Cancers
Accent Therapeutics
NCT06546553 TERMINATED A Study to Learn About How Different Amounts of the Study Medicine PF-07826390 Act in the Body of People With Cancer When Taken Alone or With Other Anti-cancer Medicines.
Pfizer
NCT03388619 COMPLETED Highly Conformal, Hypofractionated, Focally Dose Escalated Post-Prostatectomy Radiotherapy
National Cancer Institute (NCI)
NCT05381909 TERMINATED A Study of BGB-24714 as Monotherapy and With Combination Therapies in Participants With Solid Tumors
BeiGene
NCT05233436 TERMINATED PF-07265028 As Single Agent And In Combination With Sasanlimab in Advanced or Metastatic Solid Tumors
Pfizer
NCT05578092 TERMINATED A Phase 1 Study of MRTX0902 in Solid Tumors With Mutations in the KRAS MAPK Pathway
Mirati Therapeutics Inc.
NCT03964233 COMPLETED A Study in Patients With Different Types of Advanced Cancer (Solid Tumors) to Test Different Doses of BI 907828 (Brigimadlin) in Combination With BI 754091 (Ezabenlimab) and BI 754111 or BI 907828 (Brigimadlin) in Combination With BI 754091 (Ezabenlimab)
Boehringer Ingelheim
NCT02021422 COMPLETED A Pilot, Prospective, Non-randomized Evaluation of the Safety of Anakinra Plus Standard Chemotherapy
Baylor Research Institute
NCT05638334 TERMINATED Immuno-positron Emission Tomography Study of 89Zr-S095012 in Patients With Advanced Solid Tumours
Institut de Recherches Internationales Servier
NCT04397276 COMPLETED A Study of JNJ-70218902 in Participants With Advanced Stage Solid Tumors
Janssen Research & Development, LLC
NCT05100251 TERMINATED Clinical Trial of WBC100 on Advanced Solid Tumor
Zhejiang University
NCT02073994 COMPLETED Study of Orally Administered AG-120 in Subjects With Advanced Solid Tumors, Including Glioma, With an IDH1 Mutation
Institut de Recherches Internationales Servier
NCT05800964 COMPLETED Study to Explore the Safety, Tolerability, and Pharmacokinetics of AMG 305 in Subjects With Advanced Solid Tumors
Amgen
NCT03065062 SUSPENDED Study of the CDK4/6 Inhibitor Palbociclib (PD-0332991) in Combination With the PI3K/mTOR Inhibitor Gedatolisib (PF-05212384) for Patients With Advanced Squamous Cell Lung, Pancreatic, Head & Neck and Other Solid Tumors
Dana-Farber Cancer Institute
NCT02909777 COMPLETED Trial of CUDC-907 in Children and Young Adults With Relapsed or Refractory Solid Tumors, CNS Tumors, or Lymphoma
Dana-Farber Cancer Institute
NCT01534598 COMPLETED FdCyd and THU for Advanced Solid Tumors
National Cancer Institute (NCI)
NCT06331559 TERMINATED Study of SIM0501 Alone and in Combination in Patients With Advanced Solid Tumors
Jiangsu Simcere Pharmaceutical Co., Ltd.
NCT02122913 COMPLETED A Study to Test the Safety of the Investigational Drug Larotrectinib in Adults That May Treat Cancer
Bayer
NCT05478486 COMPLETED Assessment of Safety, Tolerability and PK Profile of MSP008-22 in Patients With Advanced Solid Tumours
Godavari Biorefineries Limited
NCT05372367 COMPLETED A Study in People With Advanced Cancer to Test Whether the Amount of BI 907828 in the Blood is Influenced by Taking an OATP Inhibitor or a CYP3 Inhibitor
Boehringer Ingelheim
NCT04902313 COMPLETED Cultivating Resilience in Oncology Practice
Linkoeping University
NCT06560645 TERMINATED A Study of PRT7732, an Oral SMARCA2 Degrader, in Patients With Advanced or Metastatic Solid Tumors With a SMARCA4 Mutation
Prelude Therapeutics
NCT03323944 TERMINATED CAR T Cell Immunotherapy for Pancreatic Cancer
University of Pennsylvania
NCT06457997 TERMINATED A Study of PHN-010 in Patients With Advanced Solid Tumors
Pheon Therapeutics
NCT02952248 COMPLETED A Trial to Find and Investigate a Safe Dose of a New Substance (BI 754091) for Patients With Solid Tumours
Boehringer Ingelheim
NCT04640480 COMPLETED Dose-finding Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of SNB-101(SN-38) in Patients With Tumors
SN BioScience
NCT04991480 COMPLETED A Study of ART4215 for the Treatment of Advanced or Metastatic Solid Tumors
Artios Pharma Ltd
NCT03156114 COMPLETED This Study Tests the New Medicine BI 754111 Alone or in Combination With Another New Substance BI 754091 in Patients With Advanced Cancer. The Study Tests Different Doses to Find the Best Dose for Continuous Treatment.
Boehringer Ingelheim
NCT00923806 TERMINATED Gene Therapy Using Anti-CEA Cells to Treat Metastatic Cancer
National Cancer Institute (NCI)
NCT05868915 TERMINATED HV-101 for Patients With Advanced Solid Tumors
Hervor Therapeutics
NCT04544995 TERMINATED Dose Escalation and Cohort Expansion Study of Niraparib and Dostarlimab in Paediatric Participants With Solid Tumors (SCOOP)
GlaxoSmithKline
NCT06334783 TERMINATED TIL for Patients With Advanced Solid Tumor
Hervor Therapeutics
NCT02856425 COMPLETED Trial Of Pembrolizumab And Nintedanib
Gustave Roussy, Cancer Campus, Grand Paris
NCT06299761 TERMINATED Study of the RNR Inhibitor BBI-825 in Subjects With Tumors With Resistance Gene Amplifications
Boundless Bio, Inc.
NCT06560632 TERMINATED Phase 1 Trial of RP-3467 Alone and in Combination With Olaparib in Participants With Advanced Solid Tumors
Repare Therapeutics
NCT03780725 TERMINATED This Study Tests How BI 754111 is Distributed in Patients With Advanced Non-small Cell Lung Cancer or Patients With Head and Neck Cancer Who Are Treated With BI 754091
Boehringer Ingelheim
NCT04587479 COMPLETED A First-in-Human Study of JAB-8263 in Adult Patients With Advanced Solid Tumors
Jacobio Pharmaceuticals Co., Ltd.
NCT05209295 TERMINATED A Study to Evaluate CC-486/Onureg in Participants With Moderate or Severe Hepatic Impairment Compared With Normal Hepatic Function in Participants With Myeloid Malignancies
Bristol-Myers Squibb
NCT05194072 TERMINATED A Study of Felmetatug Vedotin/SGN-B7H4V in Advanced Solid Tumors
Seagen, a wholly owned subsidiary of Pfizer
NCT02948426 TERMINATED Intraperitoneal Infusion of Autologous Monocytes With Sylatron (Peginterferon Alfa-2b) and Actimmune (Interferon Gamma-1b) in Women With Recurrent or Refractory Ovarian Cancer, Fallopian Tube Cancer or Primary Peritoneal Cancer
National Cancer Institute (NCI)
NCT04501276 COMPLETED A Phase 1b/2 Study of ADG116, ADG116 Combined With Anti-PD-1 Antibody or Anti-CD137 Antibody in Solid Tumors Patients
Adagene Inc
NCT03510104 COMPLETED Pharmacokinetic and Safety Study of MRX-2843 in Adults With Relapsed/Refractory Advanced and/or Metastatic Solid Tumors
Meryx, Inc.
NCT06130722 COMPLETED First-in-Human, Phase I, Open-label, Multicenter, Dose Escalation Clinical Study
Suzhou Forlong Biotechnology Co., Ltd
NCT03905148 COMPLETED Study of the Safety and Pharmacokinetics of BGB-283 (Lifirafenib) and PD-0325901 (Mirdametinib) in Participants With Advanced or Refractory Solid Tumors
BeiGene
NCT04617314 COMPLETED A Study of RC108-ADC in Subjects With Advanced Malignant Solid Tumors
RemeGen Co., Ltd.
NCT05378737 COMPLETED Evaluate the Safety, Tolerability and Pharmacokinetic Characteristics of BAT8006 for Injection
Bio-Thera Solutions
NCT05678998 COMPLETED WTX-330 in Patients With Advanced or Metastatic Solid Tumors or Non-Hodgkin Lymphoma
Werewolf Therapeutics, Inc.
NCT05864573 COMPLETED Study of ZGGS15 in Patients With Advanced Solid Tumors
Suzhou Zelgen Biopharmaceuticals Co.,Ltd
NCT06337630 TERMINATED A Study on Tuvusertib (Oral ATR Inhibitor) in Combination With PLX038 (Topo1 Inhibitor) in Patients With Advanced Solid Tumors
Institut Curie
NCT04648254 COMPLETED Oral Axl/Mer/CSF1R Selective Tyrosine Kinase Inhibitor in Patients With Advanced Solid Tumor
Qurient Co., Ltd.
NCT04045496 COMPLETED A First-in-Human, Phase 1 Study of JAB-3312 in Adult Patients With Advanced Solid Tumors
Jacobio Pharmaceuticals Co., Ltd.
NCT01695005 COMPLETED A Study of LY3039478 in Participants With Advanced Cancer
Eli Lilly and Company
NCT05025358 COMPLETED A Study of LP-118 in Patients With Advanced Tumors
Guangzhou Lupeng Pharmaceutical Company LTD.
NCT06626256 WITHDRAWN STIL101 for Injection for the Treatment of Locally Advanced, Metastatic or Unresectable Pancreatic Cancer, Colorectal Cancer, Renal Cell Cancer, Cervical Cancer and Melanoma
City of Hope Medical Center
NCT05012618 TERMINATED A Dose-escalation Study of LUNA18 in Patients With Locally Advanced or Metastatic Solid Tumors (With Expansion).
Chugai Pharmaceutical
NCT05483933 COMPLETED Phase 1b Study of SL-172154 Administered With Combination Agent(s) in Subjects With Ovarian Cancers
Shattuck Labs, Inc.
NCT01273168 COMPLETED Endoxifen in Adults With Hormone Receptor Positive Solid Tumors
National Cancer Institute (NCI)
NCT06846099 COMPLETED A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Efficacy and Indications of RP903
Risen (Suzhou) Pharma Tech Co., Ltd.
NCT00576134 COMPLETED The Objective is to Respond to Patients' Needs in the Field of Larynx Replacement
University Hospital, Strasbourg, France
NCT03955640 TERMINATED Hyperthermia and Olaparib in Treating Breast Cancer Patients With Chest Wall Recurrences
Thomas Jefferson University
NCT04428788 COMPLETED Study to Evaluate the Safety and Tolerability of CC-94676 in Participants With Metastatic Castration-Resistant Prostate Cancer
Celgene
NCT04936178 COMPLETED A Study of NB003 in Patients With Advanced Malignancies
Ningbo Newbay Technology Development Co., Ltd
NCT01282697 COMPLETED Clinical Trial of Rapamycin and Irinotecan in Pediatric Patients With Refractory Solid Tumors
University Hospital, Strasbourg, France
NCT05047536 TERMINATED KZR-261 in Subjects With Advanced Solid Malignancies
Kezar Life Sciences, Inc.
NCT05240898 COMPLETED A Phase 1 Study of RO7623066 Alone and in Combination in Patients With Advanced Solid Tumors
Hoffmann-La Roche
NCT03388632 COMPLETED Recombinant Interleukin-15 in Combination With Checkpoint Inhibitors Nivolumab and Ipilimumab in People With Refractory Cancers
National Cancer Institute (NCI)
NCT03573310 COMPLETED A Study of JNJ-64619178, an Inhibitor of PRMT5 in Participants With Advanced Solid Tumors, NHL, and Lower Risk MDS
Janssen Research & Development, LLC
NCT05287399 COMPLETED Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASC61in Subjects With Advanced Solid Tumors
Ascletis Pharmaceuticals Co., Ltd.
NCT06509906 TERMINATED M9466 in Combination With Topoisomerase 1 Inhibitors-based Regimens in Advanced Solid Tumors and Colorectal Cancer (DDRiver 511)
EMD Serono Research & Development Institute, Inc.
NCT03245892 COMPLETED A Study of Carboplatin and Paclitaxel Chemotherapy With Nivolumab With or Without Ipilimumab in Patients With Ovarian Cancer
Memorial Sloan Kettering Cancer Center
NCT05165433 COMPLETED Study of NG-350A Plus Pembrolizumab in Metastatic or Advanced Epithelial Tumours (FORTIFY)
Akamis Bio
NCT04580446 COMPLETED HYHOPE: De-intensified Hypofractionated Radiation Therapy for HPV-associated Oropharynx Cancer
University of Texas Southwestern Medical Center
NCT06438783 TERMINATED TQB2928 Injection Combined Anlotinib Hydrochloride Capsule in Recurrent/Metastatic Osteosarcoma and Other Solid Tumors
Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.
NCT03595059 COMPLETED A Study With ABBV-155 Alone and in Combination With Taxane Therapy in Adults With Relapsed and/or Refractory Solid Tumors
AbbVie
NCT05417750 COMPLETED A Phase I Study of GC101 TIL in Advanced Solid Tumors
Shanghai Juncell Therapeutics
NCT03260504 TERMINATED Aldesleukin and Pembrolizumab in Treating Patients With Advanced or Metastatic Kidney Cancer
University of Washington
NCT05105971 COMPLETED Assessment of Safety and Preliminary Efficacy With BAT6026 in Solid Tumor Patients in China
Bio-Thera Solutions
NCT05155722 COMPLETED Assessment of Safety ,Tolerance and Pharmacokinetics Clinical Efficacy With BAT1308 in Advanced Solid Tumors
Bio-Thera Solutions
NCT03177291 COMPLETED Pirfenidone Combined With Standard First-Line Chemotherapy in Advanced-Stage Lung NSCLC
H. Lee Moffitt Cancer Center and Research Institute
NCT05147350 TERMINATED Study of RP-6306 With FOLFIRI in Advanced Solid Tumors
Debiopharm International SA
NCT03968653 TERMINATED Study of Oral Debio 0123 in Combination With Carboplatin in Participants With Advanced Solid Tumors
Debiopharm International SA
NCT05147272 TERMINATED Study of RP-6306 With Gemcitabine in Advanced Solid Tumors
Debiopharm International SA
NCT05252416 TERMINATED (VELA) Study of BLU-222 in Advanced Solid Tumors
Blueprint Medicines Corporation
NCT03279237 COMPLETED A Pilot Study of FOLFIRINOX in Combination With Neoadjuvant Radiation for Gastric and GE Junction Cancers
Massachusetts General Hospital
NCT03307785 COMPLETED Study of Niraparib, TSR-022, Bevacizumab, and Platinum-Based Doublet Chemotherapy in Combination With TSR-042
Tesaro, Inc.
NCT03109080 COMPLETED Olaparib & Radiation Therapy for Patients Triple Negative Breast Cancer (TNBC)
Institut Curie
NCT05586321 COMPLETED Study of Safety and Antitumor Activity of GEN1056 in Participants With Advanced Solid Tumors
Genmab
NCT06232408 TERMINATED LIONS (PLK4 Inhibitor in Advanced Solid Tumors)
Repare Therapeutics
NCT06001580 COMPLETED A Study of BR101 Injection Alone in Subjects With Advanced Solid Tumors
BioRay Pharmaceutical Co., Ltd.
NCT06289894 TERMINATED A Study of BRY805 in Participants With Advanced Solid Tumors
BioRay Pharmaceutical Co., Ltd.
NCT05668585 COMPLETED A Study to Characterize the Safety, Tolerability, and Preliminary Efficacy of CFT1946 as Monotherapy and Combination Therapy in Subjects With BRAF V600 Mutant Solid Tumors
C4 Therapeutics, Inc.
NCT05014139 TERMINATED A Study of Intravesical Enfortumab Vedotin For Treatment of Patients With Non-muscle Invasive Bladder Cancer (NMIBC)
Astellas Pharma Global Development, Inc.
NCT05938296 SUSPENDED oHSV2-PD-L1/CD3-BsAb Administered Via Intratumoral Injection
Binhui Biopharmaceutical Co., Ltd.
NCT05417386 TERMINATED FOLFIRINOX + NIS793 in Pancreatic Cancer
Colin D. Weekes, M.D., PhD
NCT02936102 TERMINATED A Study of FAZ053 Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies.
Novartis Pharmaceuticals
NCT05980416 TERMINATED Study of EO-3021 in Adult Patients With Solid Tumors Likely to Express CLDN18.2
Elevation Oncology
NCT03839524 COMPLETED A Trial Evaluating TG4050 in Ovarian Carcinoma.
Transgene
NCT05400122 SUSPENDED Natural Killer (NK) Cells in Combination With Interleukin-2 (IL-2) and Transforming Growth Factor Beta (TGFbeta) Receptor I Inhibitor Vactosertib in Cancer
David Wald
NCT04374877 COMPLETED Study of CHS-388 (Formerly Known as SRF388) in Patients With Advanced Solid Tumors
Coherus Oncology, Inc.
NCT03468426 COMPLETED A Study to Test Different Doses of BI 836880 Combined With Ezabenlimab in Patients With Advanced Non-small Cell Lung Cancer Followed by Other Types of Advanced Solid Tumours
Boehringer Ingelheim
NCT05252390 TERMINATED NUV-868 as Monotherapy and in Combination With Olaparib or Enzalutamide in Adult Patients With Advanced Solid Tumors
Nuvation Bio Inc.
NCT04017819 SUSPENDED Biodistribution&Pharmacokinetic of Position Emission Tomography(PET) Radiopharmaceutical 18F C SNAT4
Stanford University
NCT03396445 COMPLETED Study of Boserolimab (MK-5890) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Adults With Advanced Solid Tumors (MK-5890-001)
Merck Sharp & Dohme LLC
NCT05322408 COMPLETED HCW9218 in Select Advanced Solid Tumors
Masonic Cancer Center, University of Minnesota
NCT06171178 TERMINATED A Study of ASP1012 in Adults With Solid Tumors
Astellas Pharma Global Development, Inc.
NCT03564821 COMPLETED IDH1 Inhibition Using Ivosidenib as Maintenance Therapy for IDH1-mutant Myeloid Neoplasms Following Allogeneic Stem Cell Transplantation
Massachusetts General Hospital
NCT03770494 TERMINATED A Study of LY3405105 in Participants With Advanced Cancer
Eli Lilly and Company
NCT04381806 SUSPENDED Phase I Study in Advanced Malignancies With 5-ALA
Fox Chase Cancer Center
NCT03010176 COMPLETED Study of Ulevostinag (MK-1454) Alone or in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic Solid Tumors or Lymphomas (MK-1454-001)
Merck Sharp & Dohme LLC
NCT04824443 COMPLETED Exercise Therapy in Cancer Patients Who Are Recovering From COVID-19
Memorial Sloan Kettering Cancer Center
NCT06158958 TERMINATED A Study to Assess the Safety, Pharmacokinetics, and Efficacy of Intravenous (IV) ABBV-303, as Monotherapy and in Combination With IV Infused Budigalimab (ABBV-181), in Adults With Advanced Solid Tumors
AbbVie
NCT01582191 COMPLETED Vandetanib and Everolimus in Treating Patients With Advanced or Metastatic Cancer
M.D. Anderson Cancer Center
NCT01852890 COMPLETED Gemcitabine, Ascorbate, Radiation Therapy for Pancreatic Cancer, Phase I
Joseph J. Cullen
NCT02597036 TERMINATED A Study of LY3127804 With Ramucirumab in Participants With Advanced Solid Tumors
Eli Lilly and Company
NCT04568902 COMPLETED Study of H3B-6545 in Japanese Women With Estrogen Receptor (ER)-Positive, Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Breast Cancer
Eisai Co., Ltd.
NCT04543188 TERMINATED A FIH Study of PF-07284890 in Participants With BRAF V600 Mutant Solid Tumors With and Without Brain Involvement
Pfizer
NCT03144661 TERMINATED An Open-Label Safety and Tolerability Study of INCB062079 in Subjects With Advanced Hepatocellular Carcinoma and Other Malignancies
Incyte Corporation
NCT05646797 TERMINATED A Study of ASP2074 in Adults With Solid Tumors
Astellas Pharma Global Development, Inc.
NCT05858164 COMPLETED A First-in-human Study to Learn How Safe the Study Treatment BAY2862789 is, to Find the Best Dose, How it Affects the Body, What Maximum Amount Can be Given, How it Moves Into, Through and Out of the Body, and How it Acts on Different Tumors in Participants With Advanced Solid Tumors
Bayer
NCT02680795 COMPLETED Establish the PK of Belinostat in Patients With Wild-type, Heterozygous, and Homozygous UGT1A1*28 Genotypes
Acrotech Biopharma Inc.
NCT05859464 TERMINATED A Phase 1 Study of ZL-1218 in Subjects With Advanced Solid Tumors
Zai Lab (Hong Kong), Ltd.
NCT05639751 COMPLETED PRT3789 Monotherapy and in Combo w/Docetaxel in Participants w/Advanced or Metastatic Solid Tumors w/SMARCA4 Mutation
Prelude Therapeutics
NCT05082610 COMPLETED A Study of HMBD-002, a Monoclonal Antibody Targeting VISTA, as Monotherapy and Combined With Pembrolizumab, in Patients With Advanced Solid Tumors
Hummingbird Bioscience
NCT04272034 TERMINATED Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors
Incyte Corporation
NCT06336148 TERMINATED A Phase 1a/1b Study of ACTM-838 in Patients With Advanced Solid Tumors
Actym Therapeutics, Inc.
NCT05025085 COMPLETED A Study Investigating AGEN1777 in Participants With Advanced Solid Tumors
Agenus Inc.
NCT02512926 COMPLETED Carfilzomib in Combination With Cyclophosphamide and Etoposide for Children
Stanford University
NCT04982926 TERMINATED A Study of TAS2940 in Participants With Locally Advanced or Metastatic Solid Tumor Cancer
Taiho Oncology, Inc.
NCT05293496 COMPLETED A Study of MGC018 in Combination With MGD019 in Participants With Advanced Solid Tumors
MacroGenics
NCT02964013 COMPLETED Study of Vibostolimab Alone and in Combination With Pembrolizumab in Advanced Solid Tumors (MK-7684-001) ( KEYVIBE-001)
Merck Sharp & Dohme LLC
NCT04117958 TERMINATED Study of AMG 199 in Subjects With MUC17-Positive Solid Tumors Including Gastric, Gastroesophageal Junction, Colorectal, and Pancreatic Cancers
Amgen
NCT05514444 COMPLETED Study of MK-4464 as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced/Metastatic Solid Tumors (MK-4464-001)
Merck Sharp & Dohme LLC
NCT03522142 TERMINATED A Study Exploring the Safety and Tolerability of INCB081776 in Participants With Advanced Malignancies
Incyte Corporation
NCT05317078 TERMINATED A Phase 1 Safety, Tolerability, and Pharmacokinetics Study of AMG 794 With Claudin 6-positive Non-small Cell Lung Cancer, Epithelial Ovarian Cancer, and Other Malignant Solid Tumor Indications
Amgen
NCT03564691 COMPLETED Study of MK-4830 as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-4830-001)
Merck Sharp & Dohme LLC
NCT04362748 COMPLETED Study of AMG 256 in Adult Subjects With Advanced Solid Tumors
Amgen
NCT02586207 COMPLETED Pembrolizumab in Combination With CRT for LA-SCCHN
Sanford Health
NCT05976334 TERMINATED An Absorption, Distribution, Metabolism, Excretion (ADME) Study of [14C]Subasumstat in Adults With Advanced or Metastatic Solid Tumors
Takeda
NCT03972150 COMPLETED A Study to Find the Best Dose of BI 836880 Alone and in Combination With BI 754091 in Japanese Patients With Different Types of Advanced Cancer
Boehringer Ingelheim
NCT04631029 COMPLETED Testing the Addition of an Anti-cancer Drug, Entinostat, to the Usual Chemotherapy and Immunotherapy Treatment (Atezolizumab, Carboplatin and Etoposide) for Previously Untreated Aggressive Lung Cancer That Has Spread
National Cancer Institute (NCI)
NCT04215978 COMPLETED Safety and Preliminary Effectiveness of BGB-A445 in Combination With Tislelizumab in Participants With Advanced Solid Tumors
BeiGene
NCT06296056 COMPLETED Phase I Trial of Combined Immune Cell Therapy for Metastatic Stage IV Solid Tumors (SDH-Combi)
Seoul Hospital
NCT02689505 COMPLETED Weekly BI 836880 in Patients With Advanced Solid Tumors
Boehringer Ingelheim
NCT02674152 COMPLETED Dose Finding Study of BI 836880 in Patients With Solid Tumors
Boehringer Ingelheim
NCT06098651 COMPLETED A Study of DCR-STAT3 in Adults With Solid Tumors
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company
NCT04417465 COMPLETED First In Human Study With ABBV-CLS-579 When Given Alone and In Combination In Participants With Locally Advanced Or Metastatic Tumors
AbbVie
NCT04710043 COMPLETED Dose Escalation Trial of BNT152+153 in Patients With Cancer
BioNTech SE
NCT05501821 COMPLETED Study of KBA1412 in Participants With Advanced Solid Malignant Tumors
Kling Biotherapeutics B.V.
NCT06264921 TERMINATED A Study With NKT3447 for Adults With Advanced/Metastatic Solid Tumors
NiKang Therapeutics, Inc.
NCT04674748 TERMINATED To Assess the Safety, Tolerability and Pharmacokinetics of INCB086550
Incyte Biosciences Japan GK
NCT01218854 COMPLETED A Comparison of Methods for Assisting Needle Angle Selection During Image-guided Tissue Biopsy
National Institutes of Health Clinical Center (CC)
NCT05200364 TERMINATED A Study of STRO-002, an Anti-Folate Receptor Alpha Antibody Drug Conjugate, in Combination With Bevacizumab in Epithelial Ovarian Cancer
Sutro Biopharma, Inc.
NCT05385705 TERMINATED A Study of Allogenic Natural Killer Cells in Combination With Trastuzumab and Pertuzumab in Adult Patients With Refractory Metastatic Her2 Positive Breast Cancer. NK-ACT-BC_2020
Vall d'Hebron Institute of Oncology
NCT06270082 TERMINATED Study of IK-595 in RAS- or RAF-altered Advanced Tumors
Ikena Oncology
NCT06182579 TERMINATED Phase I Study of RiMO-401 With Radiation in Advanced Tumors
Coordination Pharmaceuticals, Inc.
NCT06285097 TERMINATED A Study of PF-07820435 as a Single Agent and in Combination in Participants With Advanced Solid Tumors
Pfizer
NCT04242147 TERMINATED A Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of KD033 (SAR445710) in Subjects With Metastatic or Locally Advanced Solid Tumors
Kadmon, a Sanofi Company
NCT05109832 COMPLETED A Study of Absorption-Distribution-Metabolism-Excretion (ADME) of [14C]IMP4297 to China Healthy Male Subjects
Impact Therapeutics, Inc.
NCT05390944 COMPLETED An BE Study to Compare 10mg & 20mg of IMP4297 Capsules in Healthy Chinese Subjects Under Fasting Condition
Impact Therapeutics, Inc.
NCT05904496 TERMINATED A Study of BGB-30813 Alone or in Combination With Tislelizumab in Participants With Advanced or Metastatic Solid Tumors
BeiGene
NCT05391048 COMPLETED An BE Study to Compare 10mg & 20mg of IMP4297 Capsules in Healthy Chinese Subjects Under Fed Condition
Impact Therapeutics, Inc.
NCT05989997 COMPLETED Phase I Clinical Trial of 68Ga-NOTA-SNA002
SmartNuclide Biopharma
NCT05072106 COMPLETED Study to Evaluate the Effect of Bosentan on the Pharmacokinetics of Lurbinectedin in Patients With Advanced Solid Tumors
PharmaMar
NCT03944499 COMPLETED Phase 1 Study of FS-1502 in Patients With HER2 Expressed Advanced Solid Tumors and Breast Cancer.
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.
NCT04446260 COMPLETED A Study of SHR-A1811 in Subjects With Advanced Malignant Solid Tumors
Jiangsu HengRui Medicine Co., Ltd.
NCT04344795 COMPLETED Phase 1a/1b Study of TPST-1495 as a Single Agent and in Combination With Pembrolizumab in Subjects With Solid Tumors
Tempest Therapeutics
NCT05707676 TERMINATED A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Immunogenicity of LB4330 in Patients With Advanced Solid Tumors(MEETCD8-001)
L & L Bio Co., Ltd., Ningbo, China
NCT04249843 TERMINATED Study of Safety, Pharmacokinetics, and Antitumor Activity of BGB-3245 in Participants With Advanced or Refractory Tumors
MapKure, LLC
NCT03036228 COMPLETED MTH1, A Phase I, Study on Tumors Inhibition, First in Human, First in Class
Thomas Helleday Foundation
NCT06471712 COMPLETED Clinical Study of 18F-LNC1007 Injection PET/CT
Yantai LNC Biotechnology Singapore PTE. LTD.
NCT05723640 COMPLETED The Safety and Dosimetry Study of 177Lu-LNC1004 Injection
Yantai LNC Biotechnology Singapore PTE. LTD.
NCT04879849 COMPLETED A Study of TAK-676 With Pembrolizumab After Radiation Therapy to Treat a Number of Cancers
Takeda
NCT06463782 COMPLETED Clinical Study of 68Ga-LNC1007 Injection PET/CT
Yantai LNC Biotechnology Singapore PTE. LTD.
NCT04418167 SUSPENDED JSI-1187-01 Monotherapy and in Combination With Dabrafenib for Advanced Solid Tumors With MAPK Pathway Mutations
JS InnoPharm, LLC
NCT04989387 TERMINATED Study of INCA 0186 in Subjects With Advanced Solid Tumors
Incyte Corporation
NCT05114668 COMPLETED Safety, Tolerability, and Pharmacokinetics of EVT801 in Patients With Advanced Solid Tumours
Kazia Therapeutics Limited
NCT03900442 COMPLETED Phase 1 Study of PTX-100 in Patients With Advanced Malignancies With PTCL Expansion Cohort
Prescient Therapeutics, Ltd.
NCT05063318 COMPLETED Clinical Trial of Lurbinectedin (PM01183) in Patients With Advanced Solid Tumors
PharmaMar
NCT05490043 TERMINATED A Trial of ATG-101 in Patients With Metastatic/Advanced Solid Tumors and Mature B-cell Non-Hodgkin Lymphomas
Antengene (Hangzhou) Biologics Co., Ltd.
NCT04772989 COMPLETED A Study to Evaluate AB308 in Combination With AB122 in Participants With Advanced Malignancies
Arcus Biosciences, Inc.
NCT04169321 COMPLETED Granzyme B PET Imaging Drug as a Predictor of Immunotherapy Response to Checkpoint Inhibitors
Cytosite Biopharma Inc.
NCT07138352 COMPLETED Bioavailability Study of XS003 (Nilotinib)
Xspray Pharma AB
NCT04970992 COMPLETED A Pharmacokinetic and Pharmacodynamic Study of DZ-002 in Patients With Advanced Solid Malignancies or Lymphoma
Da Zen Theranostics Inc
NCT04047862 COMPLETED Study of Ociperlimab (BGB-A1217) in Combination With Tislelizumab in Advanced Solid Tumors
BeiGene
NCT05494918 COMPLETED First-In-Human Study in Subjects With Advanced or Metastatic Solid Malignant Tumors
Alphamab (Australia) Co Pty Ltd.
NCT07138378 COMPLETED A Bioavailability Study of Nilotinib in Healthy, Adult, Human Subjects Under Fasted Conditions.
Xspray Pharma AB
NCT06074705 TERMINATED A Study of DS-1471a In Subjects With Advanced Solid Tumors
Daiichi Sankyo Co., Ltd.
NCT02784795 TERMINATED A Study of LY3039478 in Participants With Advanced or Metastatic Solid Tumors
Eli Lilly and Company
NCT07132957 COMPLETED A Study of AL8326 in Healthy Subjects
Advenchen Laboratories Nanjing Ltd.
NCT03748186 COMPLETED Study of STRO-002, an Anti-Folate Receptor Alpha (FolRα) Antibody Drug Conjugate in Ovarian & Endometrial Cancers
Sutro Biopharma, Inc.
NCT03708328 COMPLETED A Dose Escalation and Expansion Study of Lomvastomig, a PD-1/TIM-3 Bispecific Antibody, in Participants With Advanced and/or Metastatic Solid Tumors
Hoffmann-La Roche
NCT05388877 TERMINATED E6201 and Dabrafenib for the Treatment of Central Nervous System Metastases From BRAF V600 Mutated Metastatic Melanoma
Mayo Clinic
NCT04147234 COMPLETED A Study to Find the Best Dose of BI 1387446 Alone or in Combination With Ezabenlimab (BI 754091) in Patients With Different Types of Advanced or Metastatic Cancer (Solid Tumors)
Boehringer Ingelheim
NCT06263582 COMPLETED Pharmacokinetics of Intravaginal, Self-administered Artesunate Vaginal Pessaries Among Women in Kenya
UNC Lineberger Comprehensive Cancer Center
NCT06165614 COMPLETED Artesunate Pessaries (Vaginal Inserts) for Cervical Precancer in Kenya
UNC Lineberger Comprehensive Cancer Center
NCT03739931 COMPLETED Dose Escalation Study of mRNA-2752 for Intratumoral Injection to Participants in Advanced Malignancies
ModernaTX, Inc.
NCT05708924 TERMINATED MT2021-27 FT538 Recurrent Ovarian, Fallopian Tube, and Primary Peritoneal Cancer
Masonic Cancer Center, University of Minnesota
NCT07121829 TERMINATED Tovorafenib (DAY101) or in Combination With Pimasertib for Participants With Melanoma and Other Solid Tumors
Day One Biopharmaceuticals, Inc.
NCT06877533 TERMINATED A First-in-Human Open-label, Phase I/Ib Dose Escalation and Expansion Cohort Study of EOS006215 as Monotherapy and in Combination With Pembrolizumab or Other Anticancer Treatments in Participants With Advanced Solid Tumors
iTeos Belgium SA
NCT06372236 COMPLETED UTAA06 Injection for Treatment of Advanced Malignant Solid Tumors
Peking University
NCT03762447 COMPLETED A Study Exploring the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB086550 in Participants With Advanced Solid Tumors
Incyte Corporation
NCT04487236 COMPLETED Trial of ZN-A-1041 Enteric Capsules in Patients With HER2-Positive Advanced Solid Tumors
Suzhou Zanrong Pharma Limited
NCT05997342 COMPLETED A Clinical Study of TQB3912 Tablets in Patients With Advanced Malignant Tumor
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT05685472 COMPLETED MEDI5752 in Japanese Patients With Advanced Solid Tumors.
AstraZeneca
NCT02776917 COMPLETED Study of Cirmtuzumab and Paclitaxel for Metastatic or Locally Advanced, Unresectable Breast Cancer
Barbara Parker, MD
NCT05717140 WITHDRAWN Aerosolized Sargramostim Added to Immunotherapy for the Treatment of Patients With Metastatic Melanoma to the Lung
Mayo Clinic
NCT06231550 COMPLETED A Study of Axl Inhibitor FC084CSA in Patients With Advanced Malignant Solid Tumors
FindCure Biosciences (ZhongShan) Co., Ltd.
NCT02836600 COMPLETED A Study of LY3039478 in Japanese Participants With Advanced Solid Tumors
Eli Lilly and Company
NCT02903914 COMPLETED Arginase Inhibitor INCB001158 as a Single Agent and in Combination With Immune Checkpoint Therapy in Patients With Advanced/Metastatic Solid Tumors
Incyte Corporation
NCT00716417 COMPLETED Study to Determine the Maximum Tolerated Dose of BIBW 2992 (Afatinib) When Combined With Cisplatin/Paclitaxel or Cisplatin/5-FU in Patients With Advanced Solid Tumours
Boehringer Ingelheim
NCT06039384 TERMINATED A Study of INCB099280 in Combination With Adagrasib in Adults With Advanced Solid Tumors Harboring a KRASG12C Mutation
Incyte Corporation
NCT02013154 COMPLETED A Study of DKN-01 in Combination With Paclitaxel or Pembrolizumab
Leap Therapeutics, Inc.
NCT06048367 COMPLETED Carbon Nanoparticle-Loaded Iron [CNSI-Fe(II)] in the Treatment of Advanced Solid Tumor
Sichuan Enray Pharmaceutical Sciences Company
NCT02628574 COMPLETED Phase 1 Open-label Study of TRX518 Monotherapy and TRX518 in Combination With Gemcitabine, Pembrolizumab, or Nivolumab
Leap Therapeutics, Inc.
NCT03059823 COMPLETED A Phase 1 Study of INCMGA00012 in Patients With Advanced Solid Tumors
Incyte Corporation
NCT03013218 COMPLETED A Study of Evorpacept (ALX148) in Patients With Advanced Solid Tumors and Lymphoma (ASPEN-01)
ALX Oncology Inc.
NCT04610736 COMPLETED TEMOkids Study : A Phase I Pediatric Study for KIMOZO, Oral Suspension of Temozolomide
Orphelia Pharma
NCT03307629 COMPLETED Safety and Tolerability of NOX66 in Combination With Palliative Radiotherapy in Patients With Late-Stage Prostate Cancer
Noxopharm Limited
NCT04306900 COMPLETED TTX-030 in Combination With Immunotherapy and/or Chemotherapy in Subjects With Advanced Cancers
Trishula Therapeutics, Inc.
NCT05162469 COMPLETED A Study of SHR-A1909 in Subjects With Advanced Malignant Tumors
Shanghai Hengrui Pharmaceutical Co., Ltd.
NCT05391022 COMPLETED Study Evaluating Food Effect and QTc in Patients With Advanced Malignancies
Constellation Pharmaceuticals
NCT04051827 COMPLETED Drug-Drug Interaction Study of TAK-788 and Midazolam in Participants With Advanced Non-small Cell Lung Cancer (NSCLC)
Millennium Pharmaceuticals, Inc.
NCT01403974 COMPLETED Phase I Trial of BI 836845 for Various Solid Cancer
Boehringer Ingelheim
NCT03249792 TERMINATED Study of MK-2118 Administered as Intratumoral Injection as Monotherapy and in Combination With Pembrolizumab (MK-3475) or by Subcutaneous Injection in Combination With Pembrolizumab in the Treatment of Adults With Advanced/Metastatic Solid Tumors or Lymphomas (MK-2118-001)
Merck Sharp & Dohme LLC
NCT03654547 COMPLETED Safety of TT-00420 (Tinengotinib) Monotherapy in Patients With Advanced Solid Tumors and Triple Negative Breast Cancer
TransThera Sciences (Nanjing), Inc.
NCT03034304 TERMINATED A Phase I Clinical Study for Evaluating the Safety and Efficacy of MASCT-I in Patients With Advanced Solid Tumors
HRYZ Biotech Co.
NCT04257110 COMPLETED A First-in-human Study of Multiple Doses of BB-1701 in Subjects With Locally Advanced/Metastatic HER2 Expressing Solid Tumors
Bliss Biopharmaceutical (Hangzhou) Co., Ltd
NCT05983146 WITHDRAWN Phase I Study of HRS-7053 Injection in the Treatment of Patients With Advanced Malignancies
Jiangsu HengRui Medicine Co., Ltd.
NCT06886659 COMPLETED A Study to Compare PK, Immunogenicity and Safety of Trastuzumab of Incepta Pharmaceuticals Ltd With Trastuzumab (Roche)
Incepta Pharmaceuticals Ltd
NCT03853109 COMPLETED AMG 404 in Patients With Advanced Solid Tumors
Amgen
NCT06255665 COMPLETED A Study of JNJ-79032421 Targeting Mesothelin for Advanced Stage Solid Tumors
Janssen Research & Development, LLC
NCT05444530 COMPLETED A Study of VAC85135, a Neoantigen Vaccine Regimen, Concurrently Administered With Ipilimumab for the Treatment of Myeloproliferative Neoplasms
Janssen Research & Development, LLC
NCT04501770 COMPLETED A Study of M802 (HER2 and CD3) in HER2-Positive Advanced Solid Tumors
Wuhan YZY Biopharma Co., Ltd.
NCT03199586 COMPLETED Clinical Trial of Metastasis Inhibitor NP-G2-044 in Patients With Advanced or Metastatic Treatment-Refractory Solid Tumor Malignancies
Novita Pharmaceuticals, Inc.
NCT05028556 COMPLETED A Trial of Y101D, a PD-L1/TGF-β Bispecific Antibody, in Patients With Metastatic or Locally Advanced Solid Tumors
Wuhan YZY Biopharma Co., Ltd.
NCT04239092 TERMINATED 9-ING-41 in Pediatric Patients With Refractory Malignancies.
Actuate Therapeutics Inc.
NCT04501744 COMPLETED A Study of M701 (EpCAM and CD3) in Malignant Ascites
Wuhan YZY Biopharma Co., Ltd.
NCT01051635 COMPLETED A Phase I Study of Indenoisoquinolines LMP400 and LMP776 in Adults With Relapsed Solid Tumors and Lymphomas
National Cancer Institute (NCI)
NCT06235541 WITHDRAWN A First-in-human Study of GENA-104A16 in Patients With Advanced Solid Tumors
Genome & Company
NCT06161558 WITHDRAWN Erlotinib in Combination With Select Tyrosine Kinase Inhibitors in Adult Patients With Advanced Solid Tumors
National Cancer Institute (NCI)
NCT04937153 COMPLETED GEN1046 Safety and PK in Subjects With Advanced Solid Malignancies
Genmab
NCT06443710 COMPLETED Technetium [99mTc]-H7ND in Patients With Gastrointestinal Malignancies and Healthy Volunteers
Jiaxing Pharmadax Genesis Pharmaceutical Technology Co.,Ltd.
NCT02123823 COMPLETED BI 836845 in Estrogen Receptor Positive Metastatic Breast Cancer
Boehringer Ingelheim
NCT02204072 COMPLETED BI836845 Plus Enzalutamide in Castrate Resistant Prostate Cancer (CRPC)
Boehringer Ingelheim
NCT05387265 TERMINATED A Trial to Find Safe and Active Doses for an Investigational Drug, CX-904, for Patients With Advanced Solid Tumors
CytomX Therapeutics
NCT04242199 COMPLETED Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099280 in Participants With Advanced Solid Tumors
Incyte Corporation
NCT04116320 TERMINATED Focused Ultrasound Ablation and PD-1 Antibody Blockade in Advanced Solid Tumors
Craig L Slingluff, Jr
NCT01317420 COMPLETED Trial to Determine MTD of BI 836845 Administered Intravenously Once Every Three Weeks in Patients With Advanced Solid Tumours and Later a Weekly Dosing Schedule in Selected Tumour Types
Boehringer Ingelheim
NCT05323045 COMPLETED A First-in-human Dose-escalation and Expansion Study With the Antibody-drug Conjugate BYON3521
Byondis B.V.
NCT03153280 TERMINATED Dose Escalation Study of Lithium With Oxaliplatin and Capecitabine in Advanced Oesophago-Gastric or Colorectal Cancer
Cancer Trials Ireland
NCT05839600 TERMINATED A Study to Find a Suitable Dose of BI 1821736 and Test Whether it Helps People With Advanced Cancer
Boehringer Ingelheim
NCT03289962 COMPLETED A Study of Autogene Cevumeran (RO7198457) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors
Genentech, Inc.
NCT05487235 COMPLETED A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-1971 in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors
Genentech, Inc.
NCT05153330 TERMINATED Study of BMF-219, a Covalent Menin Inhibitor, in Adult Patients With AML, ALL (With KMT2A/ MLL1r, NPM1 Mutations), DLBCL, MM, and CLL/SLL
Biomea Fusion Inc.
NCT03884556 COMPLETED TTX-030 Single Agent and in Combination With Immunotherapy or Chemotherapy for Patients With Advanced Cancers
Trishula Therapeutics, Inc.
NCT05383703 COMPLETED Clinical Study of MNC-168 Enteric-coated Capsule in the Treatment of Advanced Intestinal Solid Tumor
Moon (Guangzhou) Biotechnology Co., Ltd.
NCT05274451 TERMINATED A Study to Investigate LYL797 in Adults With Solid Tumors
Lyell Immunopharma, Inc.
NCT06416436 WITHDRAWN Dose-escalation Study of Ultra-high Dose Ablative Radiosurgery With Immunotherapy for Bulky Metastatic Cancer Patients
University of Kansas Medical Center
NCT05958199 SUSPENDED A Study of NPX267 for Subjects With Solid Tumors Known to Express HHLA2/B7-H7
NextPoint Therapeutics, Inc.
NCT05055518 SUSPENDED APL-102 Capsule in Patients With Advanced Solid Tumors
Apollomics Inc.
NCT03990233 COMPLETED A Trial of BI 765063 Monotherapy and in Combination With BI 754091 in Patients With Advanced Solid Tumours
OSE Immunotherapeutics
NCT04991129 TERMINATED The Safety and Efficacy of Multiple-dose of WJ01024 in Subject With Advanced Cancer
Suzhou Junjing BioSciences Co., Ltd.
NCT06630247 TERMINATED A Dose-escalation, Dose-finding, and Expansion Study of XL495 in Participants With Locally Advanced or Metastatic Solid Tumors
Exelixis
NCT03918278 COMPLETED A Study of MK-0482 as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-0482-001)
Merck Sharp & Dohme LLC
NCT02279433 COMPLETED A First-in-human Study to Evaluate the Safety, Tolerability and Pharmacokinetics of DS-6051b
Nuvation Bio Inc.
NCT03099174 COMPLETED This Study in Patients With Different Types of Cancer (Solid Tumours) Aims to Find a Safe Dose of Xentuzumab in Combination With Abemaciclib With or Without Hormonal Therapies. The Study Also Tests How Effective These Medicines Are in Patients With Lung and Breast Cancer
Boehringer Ingelheim
NCT04613492 TERMINATED A Study of MEDI9253 in Combination With Durvalumab in Select Solid Tumors
AstraZeneca
NCT04730843 COMPLETED A Study of ES102 (OX40 Agonist) in Patients With Advanced Solid Tumors
Elpiscience Biopharma, Ltd.
NCT04991506 COMPLETED A Study of ES102 (OX40 Agonist) in Combination With JS001 in Patients With Advanced Solid Tumors
Elpiscience Biopharma, Ltd.
NCT06007482 COMPLETED A Study of ES009 in Subjects With Locally Advanced or Metastatic Solid Tumors
Elpiscience Biopharma Australia Pty. Ltd.
NCT04975958 COMPLETED Double/Triple Combinations of AN2025, AN0025 and Atezolizumab in Advanced Solid Tumors
Adlai Nortye Biopharma Co., Ltd.
NCT07030439 COMPLETED A Bioequivalence Study to Compare Senaparib Manufactured at 2 Sites in Healthy Subjects in Fasting State
Impact Therapeutics, Inc.
NCT05594043 COMPLETED A Study of MK-6598 as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Advanced Solid Tumors (MK-6598-001)
Merck Sharp & Dohme LLC
NCT04278859 COMPLETED Safety, Tolerability and Pharmacokinetics of a Recombinant Humanized mAb Specific to B-and T-Lymphocyte Attenuator (BTLA) for Injection in Subjects With Advanced Malignancies
Shanghai Junshi Bioscience Co., Ltd.
NCT02145741 COMPLETED Weekly Intravenous Administrations of BI 836845 in Japanese Patients With Advanced Solid Tumours
Boehringer Ingelheim
NCT06719973 WITHDRAWN Phase 1 Study of M9466 Combined With Carboplatin and Platinum-based Anticancer Therapy (DDRiver 521)
EMD Serono Research & Development Institute, Inc.
NCT05788484 COMPLETED A Study of CDX-585 in Patients With Advanced Malignancies
Celldex Therapeutics
NCT05625412 COMPLETED A Study of BMS-986360/CC-90001 Alone and in Combination With Chemotherapy or Nivolumab in Advanced Solid Tumors
Bristol-Myers Squibb
NCT01351103 COMPLETED A Study of LGK974 in Patients With Malignancies Dependent on Wnt Ligands
Novartis Pharmaceuticals
NCT06381050 COMPLETED The Clinical Study of SHR-7631 for Injection in Patients With Advanced Solid Tumors
Suzhou Suncadia Biopharmaceuticals Co., Ltd.
NCT07019194 COMPLETED An Bioequivalence Study to Compare 10mg & 20mg of Senaparib Capsules in Healthy Chinese Subjects Under Fasting Condition
Impact Therapeutics, Inc.
NCT04986865 TERMINATED A Study ATG-101 in Patients With Metastatic/Advanced Solid Tumors and Mature B-cell Non-Hodgkin Lymphomas
Antengene Biologics Limited
NCT02836795 COMPLETED Safety and Tolerability of Recombinant Humanized Anti-PD-1 Monoclonal Antibody Toripalimab for Patients With Advanced Solid Tumors
Shanghai Junshi Bioscience Co., Ltd.
NCT02517918 COMPLETED Metronomic Chemotherapy in Patients With Advanced Solid Tumor With Bone Metastasis and Advanced Pretreated Osteosarcoma
Institut Bergonié
NCT02419495 TERMINATED Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced Malignancies
M.D. Anderson Cancer Center
NCT06535009 TERMINATED Study of ONO-7914 Alone and in Combination With ONO-4538 in Patients With Solid Tumors
Ono Pharmaceutical Co., Ltd.
NCT03277482 TERMINATED Durvalumab, Tremelimumab + Radiotherapy in Gynecologic Cancer
Dana-Farber Cancer Institute
NCT02720068 COMPLETED Study of Favezelimab (MK-4280) as Monotherapy and in Combination With Pembrolizumab (MK-3475) With or Without Chemotherapy or Lenvatinib (MK-7902) AND Favezelimab/Pembrolizumab (MK-4280A) as Monotherapy in Adults With Advanced Solid Tumors (MK-4280-001)
Merck Sharp & Dohme LLC
NCT05164666 TERMINATED A Study of TAK-103 in Adult With Solid Tumors
Takeda
NCT04405778 TERMINATED A Study of TAK-102 in Adult With Previously-Treated Solid Tumors
Takeda
NCT05192174 TERMINATED Study of NIB101 in Participants With Advanced Solid Tumors
Noile-Immune Biotech, Inc
NCT05389462 TERMINATED A Study of Mipasetamab Uzoptirine (ADCT-601) in Participants With Solid Tumors
ADC Therapeutics S.A.
NCT03508570 COMPLETED Nivolumab With or Without Ipilimumab in Treating Patients With Recurrent or High Grade Gynecologic Cancer With Metastatic Peritoneal Carcinomatosis
M.D. Anderson Cancer Center
NCT06344351 COMPLETED A Clinical Trial of TQB3006 Tablets in Patients With Advanced Malignant Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT04972981 COMPLETED A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of ADCT-901 in Participants With Selected Advanced Solid Tumors
ADC Therapeutics S.A.
NCT04642365 TERMINATED A Study to Evaluate the Safety and Tolerability of RO7296682 in Combination With Atezolizumab in Participants With Advanced Solid Tumors.
Hoffmann-La Roche
NCT04121286 COMPLETED A Study of JAB-3312 in Adult Patients With Advanced Solid Tumors in China
Allist Pharmaceuticals, Inc.
NCT04927663 TERMINATED 11C-YJH08 PET Imaging for Detection of Glucocorticoid Receptor Expression
Rahul Aggarwal
NCT05759949 COMPLETED First-in-Human Study of RLY-5836 in Advanced Breast Cancer and Other Solid Tumors
Relay Therapeutics, Inc.
NCT02318771 COMPLETED Radiation Therapy and MK-3475 for Patients With Recurrent/Metastatic Head and Neck Cancer, Renal Cell Cancer, Melanoma, and Lung Cancer
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
NCT05075564 COMPLETED A Study of ES002023 (Anti-CD39 Antibody) in Patients With Locally Advanced or Metastatic Solid Tumors
Elpiscience Biopharma, Ltd.
NCT02507583 COMPLETED Antisense102: Pilot Immunotherapy for Newly Diagnosed Malignant Glioma
david andrews
NCT05242822 TERMINATED A Study to Evaluate KIN-3248 in Participants With Advanced Tumors Harboring FGFR2 and//or FGFR3 Gene Alterations
Kinnate Biopharma
NCT05571969 SUSPENDED Study to Determine the Maximum Tolerated Dose (MTD) of PARPi 2X-121 Monotherapy and the MTD of Dovitinib in Combination With 2X-121 in Patients With Advanced Solid Tumors
Allarity Therapeutics
NCT05067972 TERMINATED A Study of PF-07260437 in Advanced or Metastatic Solid Tumors
Pfizer
NCT04261439 TERMINATED A Phase I/Ib Study of NIZ985 Alone and in Combination With Spartalizumab
Novartis Pharmaceuticals
NCT04328740 COMPLETED Phase 1 Study of Oral TP-1454
Sumitomo Pharma America, Inc.
NCT05494762 TERMINATED Safety, Pharmacokinetics, and Antitumor Activity of BGB-B167 Alone and in Combination With Tislelizumab (BGB-A317) in Participants With Advanced Solid Tumors
BeiGene
NCT05757492 TERMINATED Study to Evaluate Safety and PK of CHS-006 in Combination With Toripalimab in Patients With Advanced Solid Tumors
Coherus Oncology, Inc.
NCT05377528 COMPLETED Study of AGEN1571 in Participants With Advanced Solid Tumors
Agenus Inc.
NCT04291079 COMPLETED SRK-181 Alone or in Combination With Anti-PD-(L)1 Antibody Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (DRAGON)
Scholar Rock, Inc.
NCT03054298 COMPLETED CAR T Cells in Mesothelin Expressing Cancers
University of Pennsylvania
NCT05306444 COMPLETED CLN-418 Study on Subjects With Advanced Solid Tumors
Harbour BioMed US, Inc.
NCT05840510 TERMINATED Adagrasib in Combination With Nab-Sirolimus in Patients With Advanced Solid Tumors and Non-Small Cell Lung Cancer With a KRAS G12C Mutation (KRYSTAL -19)
Mirati Therapeutics Inc.
NCT00794131 COMPLETED Safety Study of GL-ONC1, an Oncolytic Virus, in Patients With Advanced Solid Tumors
Genelux GmbH
NCT03260322 COMPLETED A Multiple-dose Study of ASP8374, an Immune Checkpoint Inhibitor, as a Single Agent and in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors
Astellas Pharma Global Development, Inc.
NCT04301011 TERMINATED Study of TBio-6517 Given Alone or in Combination With Pembrolizumab in Solid Tumors
Turnstone Biologics, Corp.
NCT02598726 COMPLETED Curcumin and Piperine in Reducing Inflammation for Ureteral Stent-Induced Symptoms in Patients With Cancer
Mayo Clinic
NCT03954067 COMPLETED A Study of an Intratumoral Oncolytic Virus in Patients With Advanced Metastatic Solid Tumors
Astellas Pharma Global Development, Inc.
NCT03544905 COMPLETED Study to Evaluate the Safety, Tolerate, Pharmacokinetics and Preliminary Efficacy of CYH33
Haihe Biopharma Co., Ltd.
NCT06194877 TERMINATED A Study to Investigate BGB-3245 (Brimarafenib) With Panitumumab in Participants With Advanced or Metastatic RAS Mutant Colorectal and Pancreatic Ductal Cancers
MapKure, LLC
NCT02875223 TERMINATED A Safety and Efficacy Study of CC-90011 in Participants With Relapsed and/or Refractory Solid Tumors and Non-Hodgkin's Lymphomas
Celgene
NCT04836195 COMPLETED Study of PCLX-001 in R/R Advanced Solid Malignancies and B-cell Lymphoma
Pacylex Pharmaceuticals
NCT04209465 TERMINATED A Study of BDTX-189, an Orally Available Allosteric ErbB Inhibitor, in Patients With Advanced Solid Tumors.
Black Diamond Therapeutics, Inc.
NCT04886622 COMPLETED A Study of DT2216 in Relapsed/Refractory Malignancies
Dialectic Therapeutics, Inc
NCT04774952 COMPLETED Dose Escalation of RMC-5552 Monotherapy in Relapsed/Refractory Solid Tumors
Revolution Medicines, Inc.
NCT06345001 COMPLETED A First-in-Human Study to Learn About How BAY3630942 is Distributed and Processed Inside the Body When Given After BAY3547922 and How Safe it is in People With Liver Cancer or Other Select Solid Cancers
Bayer
NCT04013217 TERMINATED Evaluate Eribulin ORA in Subjects With Solid Tumors
Health Hope Pharma
NCT03724890 COMPLETED Study of Avelumab-M3814 Combinations
EMD Serono Research & Development Institute, Inc.
NCT04485416 SUSPENDED Pilot Trial of Eltrombopag in Patients Undergoing Chemotherapy for Malignant Solid Tumors
University of California, Davis
NCT05940844 WITHDRAWN Study of OB-002 in Patients With Refractory Metastatic Cancer
Orion Biotechnology Polska Sp. z o.o.
NCT05620472 COMPLETED Molecular Imaging of EpCAM Receptors Using [99mTc]Tc(CO)3-(HE)3-Ec1
Tomsk National Research Medical Center of the Russian Academy of Sciences
NCT03975387 TERMINATED Study of ASTX295 in Patients With Solid Tumors With Wild-Type p53
Taiho Oncology, Inc.
NCT04943900 COMPLETED A Study of BMS-986416 With and Without Nivolumab in Select Solid Tumors
Bristol-Myers Squibb
NCT05904236 TERMINATED Safety and Tolerability of Intravenous Administration of ICVB-1042
IconOVir Bio
NCT05737706 TERMINATED Study of MRTX1133 in Patients With Advanced Solid Tumors Harboring a KRAS G12D Mutation
Mirati Therapeutics Inc.
NCT04330664 COMPLETED Adagrasib in Combination With TNO155 in Patients With Cancer (KRYSTAL 2)
Mirati Therapeutics Inc.
NCT04925284 COMPLETED Study of XB002 in Subjects With Solid Tumors (JEWEL-101)
Exelixis
NCT02454010 COMPLETED A Dose Escalation Study of Radio-labeled Antibody for the Treatment of Advanced Cancer
Fujifilm Pharmaceuticals U.S.A., Inc.
NCT03597581 COMPLETED A Study of RGX-202-01 (Ompenaclid) as Combination Therapy in RAS Mutant Advanced Colorectal Cancer
Inspirna, Inc.
NCT03894618 COMPLETED SL-279252 (PD1-Fc-OX40L) in Subjects With Advanced Solid Tumors or Lymphomas
Shattuck Labs, Inc.
NCT05828303 WITHDRAWN A Phase 1 Study to Evaluate the Potential Drug Interactions Between Repotrectinib and Metformin, Digoxin, and Rosuvastatin in Patients With Advanced Solid Tumors
Turning Point Therapeutics, Inc.
NCT04108481 TERMINATED Immunotherapy With Y90-RadioEmbolization for Metastatic Colorectal Cancer
University of Iowa
NCT04553692 TERMINATED Phase 1a/1b Study of Aplitabart (IGM-8444) Alone or in Combination in Participants with Relapsed, Refractory, or Newly Diagnosed Cancers
IGM Biosciences, Inc.
NCT01877382 COMPLETED A Multiple Ascending Dose Study of Milademetan in Subjects With Advanced Solid Tumors or Lymphomas
Daiichi Sankyo
NCT05584111 COMPLETED Oral Administration of STC-15 in Subjects With Advanced Malignancies
STORM Therapeutics LTD
NCT03585764 TERMINATED MOv19-BBz CAR T Cells in aFR Expressing Recurrent High Grade Serous Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
University of Pennsylvania
NCT04137289 COMPLETED A Study to Find a Safe and Effective Dose of BI 905711 in Patients With Advanced Gastrointestinal Cancer
Boehringer Ingelheim
NCT04053283 COMPLETED First in Human Study With NG-641, a Tumour Selective Transgene Expressing Adenoviral Vector
Akamis Bio
NCT05043714 COMPLETED Study of NG-641 in Combination With Nivolumab in Metastatic or Advanced Epithelial Tumours
Akamis Bio
NCT01543763 COMPLETED Pazopanib in Combination With PCI-24781 in Patients With Metastatic Solid Tumors
Pamela Munster
NCT03195699 COMPLETED Oral STAT3 Inhibitor, TTI-101, in Patients With Advanced Cancers
Tvardi Therapeutics, Incorporated
NCT05463432 COMPLETED A Study of HR19024 in Subjects With Advanced Solid Tumor
Shanghai Hengrui Pharmaceutical Co., Ltd.
NCT05225584 COMPLETED Safety, PK, PD, Clinical Activity of KT-333 in Adult Patients With Refractory Lymphoma, Large Granular Lymphocytic Leukemia, Solid Tumors
Kymera Therapeutics, Inc.
NCT04239040 TERMINATED GVAX Plus Checkpoint Blockade in Neuroblastoma
Dana-Farber Cancer Institute
NCT06597786 WITHDRAWN A Study of Exercise Therapy in People With Solid Tumor Cancer
Memorial Sloan Kettering Cancer Center
NCT04586270 TERMINATED A Study of TAS0612 in Participants With Advanced or Metastatic Solid Tumor Cancer
Taiho Oncology, Inc.
NCT06873542 COMPLETED A Study of DC05F01 in Chinese Patients with Advanced or Metastatic Solid Tumors
Heronova Pharmaceuticals
NCT05023928 COMPLETED Tumor Antigen-sensitized DC Vaccine As an Adjuvant Therapy for Esophagus Cancer
Sichuan University
NCT02783300 COMPLETED An Open-label, Dose Escalation Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of GSK3326595 in Participants With Solid Tumors and Non-Hodgkin's Lymphoma
GlaxoSmithKline
NCT04882917 COMPLETED First-in-human Study of M4076 in Advanced Solid Tumors (DDRiver Solid Tumors 410)
EMD Serono Research & Development Institute, Inc.
NCT03761017 COMPLETED MGD019 DART® Protein in Unresectable/Metastatic Cancer
MacroGenics
NCT03444701 COMPLETED A Study of E7130 in Participants With Solid Tumors
Eisai Co., Ltd.
NCT04105335 COMPLETED A Study of MTL-CEBPA in Combination With a PD-1 Inhibitor in Patients With Advanced Solid Tumours (TIMEPOINT)
Mina Alpha Limited
NCT01585623 COMPLETED Drug Interaction Study of SAR302503 in Patients With Solid Tumor
Bristol-Myers Squibb
NCT05441501 COMPLETED A Study of JNJ-80038114 in Participants With Advanced Stage Prostate Cancer
Janssen Research & Development, LLC
NCT05940571 COMPLETED First Phase Clinical Trial of Single Agent MBF-362 in Solid Tumors
Medibiofarma S.L.
NCT04608045 COMPLETED Safety, Dose Tolerance, Pharmacokinetics, and Pharmacodynamics Study of CPX-POM in Patients With Advanced Solid Tumors
CicloMed LLC
NCT04728334 COMPLETED A Phase 1 Dose Escalation and Expansion Study of AK117
Akeso
NCT03261011 COMPLETED Study of the Safety, Pharmacokinetics, and Antitumor Activity of AK104 in Subjects With Advanced Solid Tumors
Akesobio Australia Pty Ltd
NCT04047290 COMPLETED A Study of AK112, a PD-1/VEGF Bispecific Antibody, for Advanced Solid Tumors
Akesobio Australia Pty Ltd
NCT03352531 COMPLETED Study of the Safety, Pharmacokinetics, and Antitumor Activity of AK105 in Subjects With Advanced Solid Tumors
Akesobio Australia Pty Ltd
NCT04572152 COMPLETED A Study of AK119 (Anti-CD73) in Combination With AK104 in Subjects With Advanced Solid Tumors
Akeso
NCT03073395 COMPLETED Preliminary Evaluation of Uptake of [68Ga]P16-093 in Metastatic Prostate and Renal Cancer
Five Eleven Pharma, Inc.
NCT01220154 COMPLETED Study of Intraperitoneal Carboplatin With IV Paclitaxel and Bevacizumab in Untreated Ovarian Cancer
David O'Malley
NCT04537715 COMPLETED Effects of Itraconazole and Rifampin on the Blood Tazemetostat Levels
Epizyme, Inc.
NCT01251562 COMPLETED Safety Study of Sterile Compound C31510 for Injection to Subjects With Solid Tumors
BPGbio
NCT05087992 COMPLETED A Study to Find the Best Dose of BI 905711 in Combination With Chemotherapy and to Test Whether This Dose Helps People With Advanced Gastrointestinal Cancers
Boehringer Ingelheim
NCT01957735 COMPLETED BP31510 (Ubidecarenone,USP) Nanosuspension for Intravenous Injection to Patients With Solid Tumors
BPGbio
NCT02966548 COMPLETED Safety Study of BMS-986016 With or Without Nivolumab in Patients With Advanced Solid Tumors
Bristol-Myers Squibb
NCT06365918 WITHDRAWN Study of VG2025 Delivered Intraperitoneally in Patients With Advanced Solid Tumors With Carcinomatosis
M.D. Anderson Cancer Center
NCT04249947 TERMINATED P-PSMA-101 CAR-T Cells in the Treatment of Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC) and Advanced Salivary Gland Cancers (SGC)
Poseida Therapeutics, Inc.
NCT05943041 COMPLETED Live Biotherapeutic Product GB104 Phase 1 Study in Colorectal Cancer
GILongevity
NCT03654716 COMPLETED Phase 1 Study of the Dual MDM2/MDMX Inhibitor ALRN-6924 in Pediatric Cancer
Dana-Farber Cancer Institute
NCT01314105 COMPLETED BIBF 1120 + Carboplatin/Pegylated Liposomal Doxorubicin (PLD) in Patients With Advanced Ovarian Cancer, Fallopian Tube Carcinoma or Primary Peritoneal Cancer
Boehringer Ingelheim
NCT02070549 COMPLETED Trametinib in Treating Patients With Advanced Cancer With or Without Hepatic Dysfunction
National Cancer Institute (NCI)
NCT00708448 COMPLETED Early Prediction of Therapeutic Response to Targeted Therapy in Stage IIIB/IV or Recurrent Lung Cancer Patients
University of Utah
NCT04805307 COMPLETED Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy, Phase 1 Study of CMG901
Keymed Biosciences Co.Ltd
NCT06172894 COMPLETED PBMC-based Leukocyte Immunotherapy
invIOs GmbH
NCT05178888 COMPLETED Adagrasib in Combination With Palbociclib in Patients With Advanced Solid Tumors (KRYSTAL-16)
Mirati Therapeutics Inc.
NCT01649271 COMPLETED Phase I Trial of Afatinib and Trastuzumab in HER2 Overexpressing Cancer.
Boehringer Ingelheim
NCT03436745 COMPLETED The Effects of Castration on the Pharmacokinetics of Zolpidem After Single Dose Administration In Men With Prostate Cancer Undergoing Androgen Deprivation Therapy Compared to Normal Healthy Females
National Cancer Institute (NCI)
NCT04999202 TERMINATED A Study to Learn How Safe the Study Drug BAY 2416964 (AhR Inhibitor) in Combination With the Treatment Pembrolizumab is, How This Combination Affects the Body, the Maximum Amount That Can be Given, How it Moves Into, Through and Out of the Body and Its Action Against Advanced Solid Cancers in Adults
Bayer
NCT05229900 TERMINATED A Study of SGN-ALPV in Advanced Solid Tumors
Seagen Inc.
NCT05241873 TERMINATED (Concerto) Study of BLU-451 in Advanced Cancers With EGFR Exon 20 Insertion Mutations
Blueprint Medicines Corporation
NCT00950742 COMPLETED Phase I Open Label Trial to Assess Safety of BIBW 2992 (Afatinib) in Combination With Herceptin® in Patients With HER2-positive Advanced Breast Cancer.
Boehringer Ingelheim
NCT04862780 TERMINATED (SYMPHONY) Phase 1/2 Study Targeting EGFR Resistance Mechanisms in NSCLC
Blueprint Medicines Corporation
NCT02667873 COMPLETED A Trial of a Novel XPO1 Inhibitor in Participants With Advanced Solid Tumors
Stemline Therapeutics, Inc.
NCT01214616 COMPLETED BIBW 2992 (Afatinib) and Vinorelbine in Japanese Patients With Advanced Solid Tumours
Boehringer Ingelheim
NCT01638533 COMPLETED Romidepsin in Treating Patients With Lymphoma, Chronic Lymphocytic Leukemia, or Solid Tumors With Liver Dysfunction
National Cancer Institute (NCI)
NCT04665921 TERMINATED A Study of SGN-STNV in Advanced Solid Tumors
Seagen Inc.
NCT05631574 TERMINATED Study of Covalent Menin Inhibitor BMF-219 in Adult Patients With KRAS Driven Non-Small Cell Lung Cancer, Pancreatic Cancer, and Colorectal Cancer
Biomea Fusion Inc.
NCT04023669 COMPLETED Evaluation of LY2606368 Therapy in Combination With Cyclophosphamide or Gemcitabine for Children and Adolescents With Refractory or Recurrent Group 3/Group 4 or SHH Medulloblastoma Brain Tumors
St. Jude Children's Research Hospital
NCT02876510 COMPLETED ACTolog in Patients With Solid Cancers
Immatics US, Inc.
NCT03441100 COMPLETED TCR-engineered T Cells in Solid Tumors: IMA202-101
Immatics US, Inc.
NCT03247309 COMPLETED TCR-engineered T Cells in Solid Tumors (ACTengine IMA201-101)
Immatics US, Inc.
NCT03628677 COMPLETED A Study to Evaluate the Safety and Tolerability of AB154 in Participants With Advanced Malignancies
Arcus Biosciences, Inc.
NCT03404791 COMPLETED A Study of TAR-200 in Participants With Muscle-Invasive Urothelial Carcinoma of the Bladder Who Are Ineligible for or Refuse Cisplatin-based Chemotherapy and Who Are Unfit for Radical Cystectomy
Janssen Research & Development, LLC
NCT02625857 COMPLETED Safety & Immunogenicity of JNJ-64041809, a Live Attenuated Double-deleted Listeria Immunotherapy, in Participants With Metastatic Castration-resistant Prostate Cancer
Janssen Research & Development, LLC
NCT05295927 TERMINATED A Study of EPI-7386 in Combination With Abiraterone Acetate Plus Prednisone, or Apalutamide in Metastatic Castration-resistant Prostate Cancer (mCRPC)
Janssen Research & Development, LLC
NCT05098405 TERMINATED First-in-human Safety and Tolerability of MP0317 in Patients With Relapsed/Refractory Advanced Solid Tumors
Molecular Partners AG
NCT04406623 COMPLETED Phase 1 Study of SL-172154 (SIRPα-Fc-CD40L) in Subjects With Ovarian Cancer
Shattuck Labs, Inc.
NCT03447470 COMPLETED Study to Evaluate the Safety and Tolerability of RXC004 in Advanced Malignancies
Redx Pharma Ltd
NCT03948763 TERMINATED A Study of mRNA-5671/V941 as Monotherapy and in Combination With Pembrolizumab (V941-001)
Merck Sharp & Dohme LLC
NCT06258330 COMPLETED Study of AM003 in Patients With Locally Advanced and Metastatic Solid Tumors
Aummune Ltd.
NCT05601219 TERMINATED A Phase 1 Study of ADA-011 for Subjects With Advanced Solid Tumors
Adanate, Inc
NCT05775406 COMPLETED Safety and Clinical Activity of KT-253 in Adult Patients with High Grade Myeloid Malignancies, Acute Lymphocytic Leukemia, Lymphoma, Solid Tumors
Kymera Therapeutics, Inc.
NCT03406871 COMPLETED Regorafenib and Nivolumab Simultaneous Combination Therapy
Kohei Shitara
NCT04074759 TERMINATED FPT155 in Patients With Advanced Solid Tumors
Five Prime Therapeutics, Inc.
NCT01121588 TERMINATED Studying An Investigational Drug Crizotinib (PF-02341066) In Non Non-Small Cell Lung Cancer Tumors That Are Positive For Anaplastic Lymphoma Kinase (ALK)
Pfizer
NCT01946789 COMPLETED A Phase 1 Study of the Clinical and Immunologic Effects of ALT-803 in Patients With Advanced Solid Tumors
Altor BioScience
NCT05613036 COMPLETED A Study in People With Advanced Cancer to Test How BI 907828 is Processed in the Body
Boehringer Ingelheim
NCT06302140 TERMINATED A Mass Balance Study of [14C]-Nanatinostat and Relative Bioavailability Study of Nanatinostat in Patients With Advanced Cancers
Viracta Therapeutics, Inc.
NCT03667716 COMPLETED COM701 (an Inhibitor of PVRIG) in Subjects With Advanced Solid Tumors.
Compugen Ltd
NCT06681870 WITHDRAWN A Study of ASP1893 in Adults With Advanced CLDN6-positive Solid Tumors
Astellas Pharma Global Development, Inc.
NCT03936959 TERMINATED A Study of LY3434172, a PD-1 and PD-L1 Bispecific Antibody, in Advanced Cancer
Eli Lilly and Company
NCT02751528 TERMINATED QUILT-3.013: Study of Ad5 [E1-, E2b-]-HER2/Neu Vaccine (ETBX-021) in Subjects With Unresectable Locally Advanced or Metastatic HER2-Expressing Breast Cancer
NantBioScience, Inc.
NCT04121676 COMPLETED Anti-CD137 and Anti-CTLA-4 Monoclonal Antibody in Patients With Advanced Cancer
Agenus Inc.
NCT03854227 TERMINATED A Dose Escalation Study Of PF-06939999 In Participants With Advanced Or Metastatic Solid Tumors
Pfizer
NCT05382936 TERMINATED Study of the PI3K Inhibitor SL-901 in Patients With Advanced Solid Tumors
Stemline Therapeutics, Inc.
NCT06012708 COMPLETED Phase 1 Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of KN510, KN713
New Cancer Cure-Bio Co.,Ltd.
NCT03329937 COMPLETED Study Evaluating the Antitumor Activity and Safety of Niraparib as Neoadjuvant Treatment in Participants With Breast Cancer
Tesaro, Inc.
NCT06560138 WITHDRAWN A Trial of SHR-4602 Infusion in Patients With SHR-4602 in Subjects With HER2-expressing or HER2-mutated Locally Advanced or Metastatic Solid Tumors
Atridia Pty Ltd.
NCT05176509 COMPLETED A Study to Evaluate the Combination of YH003, YH001 and Pembrolizumab in Subjects with Advanced Solid Tumors
Eucure (Beijing) Biopharma Co., Ltd
NCT04052971 COMPLETED To Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of ABN401 in Patients With Advanced Solid Tumors and Non-Small Cell Lung Cancer Harboring c-MET Dysregulation
Abion Inc
NCT04727554 COMPLETED Study of AMG 994 Monotherapy and AMG 994 and AMG 404 Combination Therapy in Participants With Advanced Solid Tumors
Amgen
NCT05169697 COMPLETED A Study to Assess YH002 in Combination with YH001 in Subjects with Advanced Solid Tumors
Eucure (Beijing) Biopharma Co., Ltd
NCT02630823 COMPLETED MK-3475 Immunotherapy in Endometrial Carcinoma
Washington University School of Medicine
NCT06228846 COMPLETED An Phase I Study of YY001 in Patients with Advanced Solid Tumors
Shanghai Yuyao Biotech Co., Ltd.
NCT02076906 COMPLETED MR-guided High Intensity Focused Ultrasound (HIFU) on Pediatric Solid Tumors
AeRang Kim
NCT05904730 COMPLETED Phase I Clinical Trials Investigating the Potential Efficacy of Axitinib in Patients With a BRCA 1/2 Mutations
Lynkcell Europe
NCT05116709 COMPLETED Assessment of Safety and Preliminary Clinical Efficacy with BAT6005 in Advanced Malignant Solid Tumors
Bio-Thera Solutions
NCT05279690 COMPLETED Pilot Trial of Colchicine in Urothelial Cancer and Other Solid Tumors
Icahn School of Medicine at Mount Sinai
NCT02361723 COMPLETED Phase 1a/1b BGB-290 for Advanced Solid Tumors.
BeiGene
NCT02610361 COMPLETED Study of the Safety and Pharmacokinetics of BGB-283 in Patients With Solid Tumors
BeiGene
NCT05394818 COMPLETED The Clinical Study of SHR-A2009 for Injection in Patients With Advanced Solid Tumors
Suzhou Suncadia Biopharmaceuticals Co., Ltd.
NCT02723955 COMPLETED Dose Escalation and Expansion Study of GSK3359609 in Participants With Selected Advanced Solid Tumors (INDUCE-1)
GlaxoSmithKline
NCT05414136 COMPLETED Evaluating the Safety, Tolerability, and Pharmacokinetics of BAT1006
Bio-Thera Solutions
NCT05781360 TERMINATED A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Preliminary Antitumor Activity of SIM0237 in Adult Participants with Advanced Solid Tumors
Jiangsu Simcere Pharmaceutical Co., Ltd.
NCT04404569 TERMINATED Continued Treatment for Participants Enrolled in Studies of BXQ-350
Bexion Pharmaceuticals, Inc.
NCT03150810 COMPLETED Study to Assess Safety, Tolerability and Clinical Activity of BGB-290 in Combination With Temozolomide (TMZ) in Participants With Locally Advanced or Metastatic Solid Tumors
BeiGene
NCT02746081 COMPLETED Phase I Study of BAY1436032 in IDH1-mutant Advanced Solid Tumors
Bayer
NCT04975256 TERMINATED Adagrasib in Combination With BI 1701963 in Patients With Cancer (KRYSTAL 14)
Mirati Therapeutics Inc.
NCT03518554 COMPLETED A First in Human, Dose Escalation Study of JAB-3068 (SHP2 Inhibitor) in Adult Patients With Advanced Solid Tumors
Jacobio Pharmaceuticals Co., Ltd.
NCT04908176 COMPLETED A Drug-drug Interaction Study of Avapritinib and Midazolam
Blueprint Medicines Corporation
NCT05480865 TERMINATED SHP2 Inhibitor BBP-398 in Combination With Sotorasib in Patients With Advanced Solid Tumors and a KRAS-G12C Mutation
Navire Pharma Inc., a BridgeBio company
NCT04310592 TERMINATED Natural Killer Cell (CYNK-001) Infusions in Adults with AML
Celularity Incorporated
NCT05375084 TERMINATED SHP2 Inhibitor BBP-398 in Combination With Nivolumab in Patients With Advanced Non-Small Cell Lung Cancer With a KRAS Mutation
Navire Pharma Inc., a BridgeBio company
NCT03922204 COMPLETED A Study of Bispecific Antibody MCLA-145 in Patients With Advanced or Metastatic Malignancies
Merus B.V.
NCT06619951 COMPLETED A Clinical Trial to Evaluate the Effects of Itraconazole or Rifampicin on the Pharmacokinetics of VC004 Capsules in Healthy Adult Subjects
Jiangsu vcare pharmaceutical technology co., LTD
NCT03030417 COMPLETED Indenoisoquinoline LMP744 in Adults With Relapsed Solid Tumors and Lymphomas
National Cancer Institute (NCI)
NCT05751837 COMPLETED Feasibility Study of Intra-Tumoral Lipopolysaccharide Immunotherapy for Intra-Abdominal
Patrick Wagner, MD, FACS
NCT04672434 COMPLETED Sym024 Monotherapy and in Combination With Sym021 in Patients With Advanced Solid Tumor Malignancies
Symphogen A/S
NCT05831995 TERMINATED Safety and Effectiveness of ABM-168 in Adults with Advanced Solid Tumors.
ABM Therapeutics Corporation
NCT04319757 COMPLETED ACE1702 in Subjects With Advanced or Metastatic HER2-expressing Solid Tumors
Acepodia Biotech, Inc.
NCT05018273 COMPLETED Study of VB10.NEO in Combination With Atezolizumab in Solid Tumors
Nykode Therapeutics ASA
NCT03387917 TERMINATED TLD-1, a Novel Liposomal Doxorubicin, in Patients With Advanced Solid Tumors
Swiss Cancer Institute
NCT05501912 TERMINATED A Study of ABM-1310 in Patients With BRAF V600-Mutant Advanced Solid Tumors
ABM Therapeutics Shanghai Company Limited
NCT03309150 COMPLETED ATRi Transition Rollover Study
Merck KGaA, Darmstadt, Germany
NCT05736224 COMPLETED Assessing a Natural Product Plus Bioadhesive Nanoparticle (BNP) Sunscreen
Yale University
NCT04526509 TERMINATED Master Protocol to Assess Safety and Dose of First Time in Human Next Generation Engineered T Cells in NY-ESO-1 and/or LAGE-1a Positive Advanced Solid Tumors
Adaptimmune
NCT02702492 TERMINATED PAK4 and NAMPT in Patients With Solid Malignancies or NHL (PANAMA)
Karyopharm Therapeutics Inc
NCT05246111 COMPLETED Berzosertib Human Mass Balance Study (DDRiver Solid Tumors 208)
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
NCT02143401 COMPLETED Navitoclax and Sorafenib Tosylate in Treating Patients With Relapsed or Refractory Solid Tumors
National Cancer Institute (NCI)
NCT00909025 COMPLETED Safety and Tolerability Study of Claudiximab in Patients With Advanced Gastroesophageal Cancer
Ganymed Pharmaceuticals GmbH
NCT05357911 COMPLETED A Study on the Effect of AB-106 on the Pharmacokinetics of Digoxin
Nuvation Bio Inc.
NCT02972034 TERMINATED Study of MK-8353 in Combination With Pembrolizumab (MK-3475) in Participants With Advanced Malignancies (MK-8353-013)
Merck Sharp & Dohme LLC
NCT05357820 COMPLETED A Study of AB-106 in Chinese Healthy Adult Men Evaluated the Effects of Itraconazole and Rifampicin on AB-106 PK
Nuvation Bio Inc.
NCT00739453 COMPLETED A Phase 1 Dose-escalation Study of OSI-906 and Erlotinib (Tarceva®)
Astellas Pharma Inc
NCT05990920 COMPLETED Study of Allogeneic Blood-derived Natural Killer Cells to Evaluate Safety and Tolerability in Cancer Refractory to Conventional Therapy
NKGen Biotech, Inc.
NCT03027128 COMPLETED QUILT-3.028: Study of haNK™ for Infusion in Subjects With Metastatic or Locally Advanced Solid Tumors
ImmunityBio, Inc.
NCT03834662 COMPLETED A Trial of AVID200, a Transforming Growth Factor β (TGFβ) Inhibitor, in Patients Malignancies
Bristol-Myers Squibb
NCT03166631 TERMINATED A Trial to Find the Safe Dose for BI 891065 Alone and in Combination With BI 754091 in Patients With Incurable Tumours or Tumours That Have Spread
Boehringer Ingelheim
NCT05228015 TERMINATED Oral TEAD Inhibitor Targeting the Hippo Pathway in Subjects with Advanced Solid Tumors
Ikena Oncology
NCT02619253 COMPLETED Phase I/Ib Study of Pembrolizumab With Vorinostat for Patients With Advanced Renal or Urothelial Cell Carcinoma
Nabil Adra
NCT04145297 COMPLETED Ulixertinib (BVD-523) and Hydroxychloroquine in Patients W Advanced MAPK-Mutated Gastrointestinal Adenocarcinomas
University of Utah
NCT02699515 COMPLETED MSB0011359C (M7824) in Participants With Metastatic or Locally Advanced Solid Tumors
Merck KGaA, Darmstadt, Germany
NCT05784597 COMPLETED A Study to Evaluate the Safety and Dosimetry of 68Ga-labelled OncoFAP Derivatives in Solid Tumors
Philogen S.p.A.
NCT02009449 COMPLETED A Phase 1 Study of Pegilodecakin (LY3500518) in Participants With Advanced Solid Tumors
Eli Lilly and Company
NCT05712889 COMPLETED Phase 1 Dose Escalation Study for VIP236 in Patients With Advanced Cancer
Vincerx Pharma, Inc.
NCT02635672 COMPLETED Phase I Dose Escalation Study for VIP152 in Patients With Advanced Cancer
Vincerx Pharma, Inc.
NCT02261532 COMPLETED A Phase I Study of TAS-102 in Solid Tumors
Taiho Pharmaceutical Co., Ltd.
NCT05943990 TERMINATED Study of GSK3845097 in Previously Treated Participants With Advanced Synovial Sarcoma and Myxoid/Round Cell Liposarcoma
Adaptimmune
NCT03945253 COMPLETED Study of ASP8374, an Immune Checkpoint Inhibitor, in Japanese Patients With Advanced Solid Tumors
Astellas Pharma Inc
NCT06048705 TERMINATED Study of GSK3901961 In Previously Treated Advanced (Metastatic OR Unresectable) Synovial Sarcoma/ Myxoid/Round Cell Liposarcoma, and Previously Treated Metastatic Non-Small Cell Lung Cancer
Adaptimmune
NCT04855929 COMPLETED A Study Evaluating Safety and Therapeutic Activity of ANV419 in Patients with Advanced Cancer.
Anaveon AG
NCT03833427 TERMINATED Study of Selumetinib (MK-5618) in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic Solid Tumors (MK-5618-001)
Merck Sharp & Dohme LLC
NCT01529684 COMPLETED A Study to Look at How a Single Oral Dose of 14C-OSI-906 is Absorbed, Broken Down and Eliminated in the Body
Astellas Pharma Global Development, Inc.
NCT04313868 COMPLETED GEN2 Directed Cancer Immunotherapy Trial
GenVivo, Inc.
NCT06448364 TERMINATED A Study in Advanced/Metastatic Solid Tumors With the Study Medicine (PF-07329640) When Given Alone or In Combination
Pfizer
NCT02113878 COMPLETED Phase Ib Study of BKM120 With Cisplatin and XRT in High Risk Locally Advanced Squamous Cell Cancer of Head and Neck
Dana-Farber Cancer Institute
NCT04504669 COMPLETED First Time in Human Study of AZD8701 With or Without Durvalumab in Participants With Advanced Solid Tumours
AstraZeneca
NCT02456883 COMPLETED Study to Investigate the Absorption, Metabolism and Excretion of [14C] ASP2215 in Patients With Advanced Solid Tumors
Astellas Pharma Global Development, Inc.
NCT04795713 TERMINATED Study of MT-6402 in Subjects With Advanced Solid Cancer That Expresses PD-L1
Molecular Templates, Inc.
NCT03666143 COMPLETED A Phase 1b Study to Assess Sitravatinib in Combination With Tislelizumab in Participants With Advanced Solid Tumors
BeiGene
NCT01359982 COMPLETED Safety and Pharmacokinetic Study of RRx-001 in Cancer Subjects
EpicentRx, Inc.
NCT04094506 COMPLETED Study of ASP1948, Targeting an Immune Modulatory Receptor, in Japanese Patients With Advanced Solid Tumors
Astellas Pharma Inc
NCT03565445 COMPLETED A Study of ASP1948, Targeting an Immune Modulatory Receptor as a Single Agent and in Combination With a PD-l Inhibitor (Nivolumab or Pembrolizumab) in Subjects With Advanced Solid Tumors
Astellas Pharma Global Development, Inc.
NCT02199236 COMPLETED Dose Escalation Trial of Endoluminal High-Dose-Rate Brachytherapy With Concurrent Chemotherapy for Rectal or Anal Cancer in Patients With Recurrent Disease or Undergoing Non-Operative Management
Memorial Sloan Kettering Cancer Center
NCT03799003 TERMINATED A Study of ASP1951 in Subjects With Advanced Solid Tumors
Astellas Pharma Global Development, Inc.
NCT03457532 COMPLETED A Phase I Study of SCC244 in Patients with Advanced MET Alterations Solid Tumors
Haihe Biopharma Co., Ltd.
NCT04635995 COMPLETED Phase 1 Trial of LVGN7409 (CD40 Agonist Antibody) as Single Agent and Combination Therapies in Advanced or Metastatic Malignancy
Lyvgen Biopharma Holdings Limited
NCT04130542 COMPLETED Phase 1 Trial of LVGN6051 as Single Agent and in Combination With Keytruda (Pembrolizumab) in Advanced or Metastatic Malignancy
Lyvgen Biopharma Holdings Limited
NCT02383368 COMPLETED A Dose Escalation and Expansion Study of ASP4132 to Subjects With Advanced Refractory Tumors and Lymphoma
Astellas Pharma Global Development, Inc.
NCT05231733 WITHDRAWN Study of SPX-101 in Subjects With Advanced or Refractory Solid Tumors
SparX Biotech(Jiangsu) Co., Ltd.
NCT04525014 TERMINATED RRx-001 Given With Irinotecan and Temozolomide for Pediatric Patients With Recurrent or Progressive Malignant Solid and Central Nervous System Tumors
EpicentRx, Inc.
NCT04096638 COMPLETED Safety and Efficacy of SB 11285 Alone and in Combination With Atezolizumab in Patients With Advanced Solid Tumors
invoX Pharma Limited
NCT02038673 COMPLETED An Open-label Phase I Study of Orally Available Novel Small-molecule Fibroblast Growth Factor Receptors (FGFR) 1,2,3 and 4 Inhibitor, ASP5878 at Single and Multiple Doses in Patients With Solid Tumors
Astellas Pharma Inc
NCT05076591 SUSPENDED IMM2902, a HER2/SIRPα Bispecific MAb-Trap Antibody-receptor Fusion Protein, in Patients with HER2-expressing Advanced Solid Tumors
ImmuneOnco Biopharmaceuticals (Shanghai) Inc.
NCT03215511 COMPLETED A Study to Test the Safety of the Investigational Drug Selitrectinib in Children and Adults That May Treat Cancer
Bayer
NCT04870840 COMPLETED Image-guided Proton Therapy for the Treatment of Locally Advanced Unresectable Head and Neck Cancer
M.D. Anderson Cancer Center
NCT02265536 COMPLETED A Study of LY3022855 In Participants With Breast or Prostate Cancer
Eli Lilly and Company
NCT03960060 TERMINATED A Study of CCT301-59 CAR T Therapy in Adult Subjects With Recurrent or Refractory Solid Tumors
Shanghai PerHum Therapeutics Co., Ltd.
NCT03994211 COMPLETED Study to Investigate the Effect of Rifampin and Itraconazole on the Action of Pamiparib in Participants With Cancer
BeiGene
NCT03809624 TERMINATED Study of INBRX-105 and INBRX-105 With Pembrolizumab in Patients With Solid Tumors Including Head and Neck Cancer
Inhibrx Biosciences, Inc
NCT03641586 COMPLETED The Study of BGB-283 in Chinese Subjects With Local Advanced or Metastatic Malignant Solid Tumor
BeiGene
NCT04800822 TERMINATED PF-07284892 in Participants With Advanced Solid Tumors
Pfizer
NCT04270864 TERMINATED Intratumoral Tilsotolimod, a TLR-9 Agonist, Together With Intratumoral Ipilimumab and Intravenous Nivolumab in Patients With Advanced Cancers
Gustave Roussy, Cancer Campus, Grand Paris
NCT05200013 COMPLETED BAT7104 in Patients With Advanced Solid Tumours
Bio-Thera Solutions
NCT05814536 TERMINATED IDH1 Inhibitor AB-218 in Patients With Advanced IDH1 Mutant Cholangiocarcinoma and Other Solid Tumor
AnHeart Therapeutics Inc.
NCT05043298 COMPLETED A Phase Ia/Ib Clinical Trial of IBI360 Monotherapy or in Combination With Sintilimab and (or) Chemotherapy in Advanced or Metastatic Solid Tumors
Innovent Biologics (Suzhou) Co. Ltd.
NCT06554639 COMPLETED A Drug-Drug Interaction Study of Diltiazem and MK-5684 in Healthy Adult Male Participants (MK-5684-011)
Merck Sharp & Dohme LLC
NCT04908046 COMPLETED A Study of HMPL-295S1 in Patients With Advanced Malignant Solid Tumors
Hutchmed
NCT02516813 COMPLETED Phase 1 Trial of MSC2490484A, an Inhibitor of a DNA-dependent Protein Kinase, in Combination With Radiotherapy
EMD Serono Research & Development Institute, Inc.
NCT06161493 WITHDRAWN ZEN003694 Combined With Niraparib in Patients With Metastatic or Recurrent Solid Tumors
Haider Mahdi
NCT04236154 COMPLETED "Prescribing" Exercise to Cancer Patients At High-Risk for Falls
Mayo Clinic
NCT03087591 COMPLETED APN401 in Treating Patients With Recurrent or Metastatic Pancreatic Cancer, Colorectal Cancer, or Other Solid Tumors That Cannot Be Removed by Surgery
Wake Forest University Health Sciences
NCT04861987 COMPLETED A Study of the Safety and PK of PCS6422 (Eniluracil) with Capecitabine in Patients with Advanced, Refractory GI Tract Tumors
Processa Pharmaceuticals
NCT05390710 COMPLETED PhI to Solid Tumors and PhII to Locally Advanced or mTNBC
Laekna Limited
NCT04021277 TERMINATED PS101-mediated ACT With Chemotherapy in Liver Metastases From Cancer of Gastrointestinal Origin
EXACT Therapeutics AS
NCT01127178 TERMINATED Study of Poly (ADP-Ribose) Polymerase (PARP) Inhibitor E7016 in Combination With Temozolomide in Subjects With Advanced Solid Tumors
Eisai Inc.
NCT03466268 COMPLETED Study to Evaluate the Safety and Anti-tumor Activity of SCC244
Haihe Biopharma Co., Ltd.
NCT06631625 COMPLETED Effect of Addition of Dexmedetomidine or Ketamine to Intravenous Infusion of Lidocaine on Proinflammatory Cytokines in Pelvi-abdominal Cancer Surgeries.
Alexandria University
NCT03220347 TERMINATED A Study to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of CC-90010 in Subjects With Advanced Solid Tumors and Relapsed/Refractory Non-Hodgkin's Lymphomas
Celgene
NCT03507491 COMPLETED Nab-paclitaxel in Combination with Gemcitabine for Pediatric Relapsed and Refractory Solid Tumors
Emory University
NCT05410002 COMPLETED Diet Effect on Cancer Treatment Outcome
Optimal Health Research
NCT02480374 COMPLETED Study of Safety & Biological Activity of IP IMNN-001 (also Known As GEN-1) with Neoadjuvant Chemo in Ovarian Cancer
Imunon
NCT03936465 COMPLETED Study of the Bromodomain (BRD) and Extra-Terminal Domain (BET) Inhibitors BMS-986158 and BMS-986378 in Pediatric Cancer
Dana-Farber Cancer Institute
NCT03946800 COMPLETED A Study of MEDI1191 in Sequential and Concurrent Combination With Durvalumab in Subjects With Advanced Solid Tumors
MedImmune LLC
NCT04659629 COMPLETED NL-201 Monotherapy and in Combination With Pembrolizumab in Patients With Relapsed or Refractory Cancer
Neurogene Inc.
NCT03864042 COMPLETED Pharmacokinetic Drug-drug Interaction Study of Encorafenib and Binimetinib on Probe Drugs in Patients With BRAF V600-mutant Melanoma or Other Advanced Solid Tumors
Pfizer
NCT02791334 COMPLETED A Study of Anti-PD-L1 Checkpoint Antibody (LY3300054) Alone and in Combination in Participants With Advanced Refractory Solid Tumors
Eli Lilly and Company
NCT02338622 COMPLETED Trial of Olaparib in Combination With AZD5363 (ComPAKT)
Royal Marsden NHS Foundation Trust
NCT02193633 COMPLETED A Phase I Trial of the Combination of AZD2014 and Weekly Paclitaxel.
Royal Marsden NHS Foundation Trust
NCT05298592 COMPLETED A Study of BMS-986406 as Monotherapy and Combination Therapies in Participants With Advanced Tumors
Bristol-Myers Squibb
NCT03251378 COMPLETED A Multi-Center, Open-Label Study of Fruquintinib in Solid Tumors and Colorectal, and Breast Cancers
Hutchison Medipharma Limited
NCT04672460 COMPLETED A Bioequivalence Study Between the Proposed and Current Talazoparib Capsule Formulation and Food Effect Study for the Proposed Talazoparib Capsule Formulation in Participants With Advanced Solid Tumors
Pfizer
NCT04130763 COMPLETED Fecal Microbiota Transplant (FMT) Capsule for Improving the Efficacy of Anti- PD-1
Peking University
NCT04713891 COMPLETED A Study of KF-0210 in Advanced Solid Tumors Patients
Keythera Pharmaceuticals (Australia) Pty Ltd
NCT02944864 TERMINATED A Phase I Study of TQ-B3395 on Tolerance and Pharmacokinetics
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT03447314 COMPLETED Study of a Combination of GSK1795091 and Immunotherapies in Subjects With Advanced Solid Tumors
GlaxoSmithKline
NCT02994953 TERMINATED A Phase Ib Study to Evaluate the Safety, Tolerability, and Pharmacokinetics (PK) of Avelumab in Combination With M9241(NHS-IL12) (JAVELIN IL-12)
EMD Serono Research & Development Institute, Inc.
NCT01346358 COMPLETED A Study of IMC-CS4 in Subjects With Advanced Solid Tumors
Eli Lilly and Company
NCT01394016 COMPLETED A Phase 1 Study of LY2835219 In Participants With Advanced Cancer
Eli Lilly and Company
NCT03604783 TERMINATED Phase 1, First-in-human Study of Oral TP-1287 in Patients with Advanced Solid Tumors
Sumitomo Pharma America, Inc.
NCT03873883 COMPLETED First-in-Human Study of EOS100850 (Inupadenant) in Patients with Cancer
iTeos Therapeutics
NCT05655598 WITHDRAWN TAS-116 Plus Palbociclib in Breast and Rb-null Cancer
Brown University
NCT03744403 COMPLETED A Study of CS1001 in Subjects with Advanced Solid Tumors
CStone Pharmaceuticals
NCT04182516 TERMINATED Study of NMS-03305293 in Pts with Selected Advanced/Metastatic Solid Tumors
Nerviano Medical Sciences
NCT04335253 COMPLETED First-In-Human Study of EOS884448 in Participants with Advanced Cancers.
iTeos Therapeutics
NCT04087018 COMPLETED Study to Evaluate Safety and Clinical Activity of AB122 in Biomarker Selected Participants With Advanced Solid Tumors
Arcus Biosciences, Inc.
NCT03028766 COMPLETED WEE1 Inhibitor with Cisplatin and Radiotherapy: a Trial in Head and Neck Cancer
University of Birmingham
NCT05002868 COMPLETED Safety, Pharmacokinetics and Anti-tumor Activity of RP12146, in Patients With Solid Tumors
Rhizen Pharmaceuticals SA
NCT04965818 TERMINATED Phase 1b/2 Study of Futibatinib in Combination With Binimetinib in Patients With Advanced KRAS Mutant Cancer
Taiho Oncology, Inc.
NCT02903771 COMPLETED Phase I Study of Cantrixil in Patients With Ovarian Cancer, Fallopian Tube Cancer or Primary Peritoneal Cancer.
Kazia Therapeutics Limited
NCT05117177 COMPLETED New Formulation Study of Inupadenant (EOS100850) in Patients with Cancer
iTeos Therapeutics
NCT03783403 TERMINATED A Study of CC-95251, a Monoclonal Antibody Directed Against SIRPα, in Participants With Advanced Solid and Hematologic Cancers
Celgene
NCT03523819 COMPLETED A Study of CS1002 in Subjects with Advanced Solid Tumors
CStone Pharmaceuticals
NCT04742556 COMPLETED A Study to Test Different Doses of BI 3011441 in Japanese People With Different Types of Advanced Cancer (NRAS/KRAS Mutation Positive)
Boehringer Ingelheim
NCT03516123 COMPLETED A Study of CS3006 in Subjects with Locally Advanced or Metastatic Solid Tumors
CStone Pharmaceuticals
NCT02301104 COMPLETED A Phase I Study of TAS-102 in Patients With Advanced Solid Tumors With Hepatic Impairment
Taiho Oncology, Inc.
NCT03410927 TERMINATED A Study of TAS0728 in Patients With Solid Tumors With HER2 or HER3 Abnormalities
Taiho Oncology, Inc.
NCT01867879 COMPLETED Study to Evaluate the Cardiac Safety of TAS-102 in Patients With Advanced Solid Tumors
Taiho Oncology, Inc.
NCT02134067 TERMINATED Dose-escalating, Safety, Tolerability and PK Study of TAS-119 in Combination With Paclitaxel in Patients With Advanced Solid Tumors
Taiho Oncology, Inc.
NCT01867866 COMPLETED Study Comparing the Pharmacokinetics of FTD as a Component of TAS-102 With FTD Alone
Taiho Oncology, Inc.
NCT02025803 COMPLETED A Safety, Tolerability and Pharmacokinetic Study of TAS-114 in Combination With Capecitabine in Patients With Advanced Solid Tumors
Taiho Oncology, Inc.
NCT01874522 COMPLETED Study Comparing the Bioavailability of TAS-102 Tablets to an Oral Solution Containing Equivalent Amounts of FTD and TPI
Taiho Oncology, Inc.
NCT02031055 COMPLETED Study of the Mass Balance of Oral FTD and TPI as Components of TAS-102 in Patients With Advanced Solid Tumors
Taiho Oncology, Inc.
NCT02301117 COMPLETED A Phase I Study of TAS-102 in Patients With Advanced Solid Tumors With Renal Impairment
Taiho Oncology, Inc.
NCT03814005 COMPLETED A Study of Pevonedistat in People With Blood Cancers or Solid Tumors With Kidney or Liver Problems
Takeda
NCT02454062 COMPLETED A Trial of TAS-114 in Combination With S-1
Taiho Oncology, Inc.
NCT04770246 TERMINATED TAS-117 in Patients With Advanced Solid Tumors Harboring Germline PTEN Mutations
Taiho Oncology, Inc.
NCT04366648 COMPLETED Safety, Tolerability and Pharmacokinetics of Injectable PEG-Irinotecan (JK-1201I) in Patients with Malignant Solid Tumor
JenKem Technology Co., Ltd.
NCT02448589 TERMINATED An Investigation of TAS-119 Monotherapy
Taiho Oncology, Inc.
NCT02965885 COMPLETED A Study of TAS-116 in Patients With Solid Tumors
Taiho Oncology, Inc.
NCT04747470 TERMINATED Study to Assess the Effects of GS-3583 in Participants With Advanced Solid Tumors
Gilead Sciences
NCT06372574 WITHDRAWN A Study of RO7617991 in Patients With Locally Advanced or Metastatic MAGE-A4-Positive Solid Tumors
Genentech, Inc.
NCT05065710 COMPLETED A Study of ZL-1211 in Patients With Advanced Solid Tumor
Zai Biopharmaceutical (Suzhou) Co., Ltd.
NCT03284723 TERMINATED PF-06804103 Dose Escalation in HER2 Positive and Negative (Negative Only in Part 2) Solid Tumors
Pfizer
NCT05088070 COMPLETED Clinical Study of SPH3348 Tablets, a C-Met Inhibitor, in Patients with Advanced Solid Tumors
Shanghai Pharmaceuticals Holding Co., Ltd
NCT06529445 COMPLETED Food Effect and Relative Bioavailability Study of VC004 Capsules in Healthy Adult Subjects
Jiangsu vcare pharmaceutical technology co., LTD
NCT02964507 TERMINATED Dose Escalation and Expansion Study of GSK525762 in Combination With Fulvestrant in Participants With Hormone Receptor-positive (HR+)/Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Advanced or Metastatic Breast Cancer
GlaxoSmithKline
NCT06004921 COMPLETED A Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of AB801 in Healthy Volunteers
Arcus Biosciences, Inc.
NCT05996445 TERMINATED A Study of XmAb®662 as Monotherapy or in Combination With Pembrolizumab in Advanced Solid Tumors
Xencor, Inc.
NCT03343054 COMPLETED A Phase 1 Study Of Talazoparib, PARP Inhibitor, In Japanese Patients With Advanced Solid Tumors
Pfizer
NCT03187288 COMPLETED Study of CFI-400945 Fumarate in Patients With Relapsed or Refractory AML or MDS
University Health Network, Toronto
NCT01606241 COMPLETED Vaccine Therapy and Cyclophosphamide in Treating Patients With Stage II-III Breast or Stage II-IV Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
Mayo Clinic
NCT04349969 COMPLETED A Study to Evaluate the Safety, Pharmacokinetics, and Antitumor Activity of AK117 as Monotherapy or in Combination With AK104
Akesobio Australia Pty Ltd
NCT02520778 COMPLETED Osimertinib and Navitoclax in Treating Patients With EGFR-Positive Previously Treated Advanced or Metastatic Non-small Cell Lung Cancer
National Cancer Institute (NCI)
NCT06216561 WITHDRAWN Intraperitoneal LSTA1 in CRS-HIPEC
University of California, San Diego
NCT05569512 TERMINATED Uproleselan With Pre-Transplant Conditioning in Hematopoietic Stem Cell Transplantation for AML
Malika Kapadia
NCT05280483 COMPLETED ABSK021 Food Effect Study in Healthy Subjects
Abbisko Therapeutics Co, Ltd
NCT03355066 TERMINATED A Study Evaluating the Safety and Pharmacokinetics of Orally Administered SM08502 in Subjects With Advanced Solid Tumors
Biosplice Therapeutics, Inc.
NCT02595866 COMPLETED Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer
National Cancer Institute (NCI)
NCT03192345 COMPLETED A First-in-human Study of the Safety, Pharmacokinetics, Pharmacodynamics and Anti-tumor Activity of SAR439459 Monotherapy and Combination of SAR439459 and Cemiplimab in Patients With Advanced Solid Tumors
Sanofi
NCT06297642 TERMINATED TQB2928 Injection Combined With Penpulimab in Treatment of Advanced Malignant Tumors.
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT06044142 COMPLETED Curcumin VS Photo-bio-modulation Therapy of Oral Mucositis in Pediatric Patients Undergoing Anti-Cancer Non-invasive Treatment
Riyadh Elm University
NCT00878423 COMPLETED Study to Assess the Safety of Escalating Doses of AT13387 in Patients With Metastatic Solid Tumors
Astex Pharmaceuticals, Inc.
NCT05764915 TERMINATED A Phase I Study of RGT-264 in Subjects With Advanced Solid Tumors
Regor Pharmaceuticals Inc.
NCT01847326 COMPLETED Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Carboplatin Followed By Chemoradiation in Treating Patients With Recurrent Head and Neck Cancer
University of Chicago
NCT05101109 COMPLETED Study to Evaluate the Safety and Tolerability of ABL501, and to Determine the Maximum Tolerated Dose (MTD) and Recommended Phase 2 Dose (RP2D) of ABL501 in Subjects With Any Progressive, Locally Advanced (Unresectable) or Metastatic Solid Tumors
ABL Bio, Inc.
NCT06172309 COMPLETED A Phase I Study of NTQ1062 in Chinese Patients With Advanced Solid Tumors
Nanjing Chia-tai Tianqing Pharmaceutical
NCT03154294 COMPLETED Evaluation of the Safety and Tolerability of TAK-228 With TAK-117 and Paclitaxel in Advanced Solid Tumors
Avera McKennan Hospital & University Health Center
NCT03329001 COMPLETED Crossover Study to Assess the Relative Bioavailability and Bioequivalence of Niraparib Tablet Compared to Niraparib Capsule
Tesaro, Inc.
NCT04675528 COMPLETED Food Effect on Pharmacokinetics and Safety of DHP107 (Liporaxel®) FEEL Study
Daehwa Pharmaceutical Co., Ltd.
NCT03435250 TERMINATED Study of AG-270 in Participants With Advanced Solid Tumors or Lymphoma With MTAP Loss
Institut de Recherches Internationales Servier
NCT05702424 COMPLETED Evaluation of IGM-7354 in Adults With Relapsed and/or Refractory Cancer
IGM Biosciences, Inc.
NCT03667482 COMPLETED Cabozantinib in Combination With Cetuximab in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Cancer
Memorial Sloan Kettering Cancer Center
NCT04305249 TERMINATED Safety and Preliminary Efficacy of ATG-017 Monotherapy or Combination Therapy With Nivolumab in Advanced Solid Tumors and Hematological Malignancies
Antengene Therapeutics Limited
NCT03641547 COMPLETED M6620 Plus Standard Treatment in Oesophageal and Other Cancer
University of Oxford
NCT05039931 WITHDRAWN A Study of GNC-035, a Tetra-specific Antibody, in Participants With Locally Advanced or Metastatic Solid Tumors
Sichuan Baili Pharmaceutical Co., Ltd.
NCT05338346 TERMINATED A Study of ATG-018 (ATR Inhibitor) Treatment in Patients With Advanced Solid Tumors and Hematological Malignancies
Antengene Discovery Limited
NCT03956056 TERMINATED Neoantigen Peptide Vaccine Strategy in Pancreatic Cancer Patients Following Surgical Resection and Adjuvant Chemotherapy
Washington University School of Medicine
NCT02857998 COMPLETED A Study of Hutchison MediPharma Limited(HMPL)-523 in Patients With Relapsed or Refractory Mature B-cell Neoplasms
Hutchison Medipharma Limited
NCT02110563 TERMINATED Phase I, Multicenter, Dose Escalation Study of DCR-MYC in Patients With Solid Tumors, Multiple Myeloma, or Lymphoma
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company
NCT04410224 COMPLETED Study of ASN004 in Patients With Advanced Solid Tumors
Kirilys Therapeutics Inc.
NCT05769959 TERMINATED Study of RO7515629 in Participants With HLA-G Positive Solid Tumors
Hoffmann-La Roche
NCT03752398 COMPLETED A Study of XmAb®23104 in Subjects With Selected Advanced Solid Tumors (DUET-3)
Xencor, Inc.
NCT03829111 COMPLETED CBM588, Nivolumab, and Ipilimumab in Treating Patients With Stage IV or Advanced Kidney Cancer
City of Hope Medical Center
NCT04505839 COMPLETED First-In-Human Dose-Escalation Study of STP1002 in Patients With Advanced-Stage Solid Tumors
ST Pharm Co., Ltd.
NCT05578820 COMPLETED Safety, Tolerability and Pharmacokinetics Investigation of Stimotimagene Copolymerplasmid
Gene Surgery LLC
NCT03934814 COMPLETED Study of TJ011133 in Participants With Relapsed/Refractory Advanced Solid Tumors and Lymphoma
I-Mab Biopharma US Limited
NCT03685591 TERMINATED PF-06952229 Treatment in Adult Patients With Advanced Solid Tumors
Pfizer
NCT04641871 COMPLETED Sym021 in Combination With Either Sym022 or Sym023 or Sym023 and Irinotecan in Patients With Recurrent Advanced Selected Solid Tumor Malignancies
Symphogen A/S
NCT05621525 TERMINATED Phase I Study of the BBP-398 in Patients With Advance Solid Tumors
LianBio LLC
NCT05594875 COMPLETED A Trial of SHR-A1921 for Injection in Subjects With Advanced Solid Tumors
Atridia Pty Ltd.
NCT03451825 TERMINATED Phase I/II Study of Avelumab in Pediatric Cancer Participants
EMD Serono Research & Development Institute, Inc.
NCT04833959 WITHDRAWN Pilot Study of 89-Zr Panitumumab in Pancreas Cancer
Stanford University
NCT03301896 TERMINATED Study of the Safety and Efficacy of LHC165 Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies
Novartis Pharmaceuticals
NCT05731934 COMPLETED The Tolerability and Pharmacokinetics of HX301 Monolactate Capsules in Patients With Advanced Solid Tumors
Hangzhou Hanx Biopharmaceuticals, Ltd.
NCT03621982 TERMINATED Study of ADCT-301 in Patients With Selected Advanced Solid Tumors
ADC Therapeutics S.A.
NCT04638491 COMPLETED Safety Tolerability Pharmacokinetic and Preliminary Efficacy in Chinese Advanced Solid Tumors Patients
Luye Pharma Group Ltd.
NCT00543387 COMPLETED Treatment of Participants With Advanced and/or Refractory Solid Tumors (MK-5108-001)
Merck Sharp & Dohme LLC
NCT00963547 TERMINATED A Study of MK-2206 in Combination With Trastuzumab and Lapatinib for the Treatment of HER2+ Solid Tumors (MK-2206-015)
Merck Sharp & Dohme LLC
NCT05309187 COMPLETED Dose-Escalation and Dose-Expansion Study of IO-202 and IO-202+Pembrolizumab in Solid Tumors
Immune-Onc Therapeutics
NCT04336098 COMPLETED Study of SRF617 in Patients With Advanced Solid Tumors
Coherus Oncology, Inc.
NCT02318329 COMPLETED Open-Label, Dose-Finding Study Evaluating Safety and PK of FPA144 in Patients With Advanced Solid Tumors
Five Prime Therapeutics, Inc.
NCT05054348 COMPLETED First-in-human Study of IO-108 as Single Agent and in Combination With a PD-1 Immune Check Point Inhibitor in Patients With Advanced Solid Tumors
Immune-Onc Therapeutics
NCT03066154 TERMINATED Oral Docetaxel (ModraDoc/r) in Combination With Hormonal Treatment and Radiation Therapy in High-risk Prostate Cancer
The Netherlands Cancer Institute
NCT02552953 COMPLETED A Pharmacologic Study of CYC065, a Cyclin Dependent Kinase Inhibitor, in Patients With Advanced Cancers
Cyclacel Pharmaceuticals, Inc.
NCT03434262 COMPLETED SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors
St. Jude Children's Research Hospital
NCT04357587 COMPLETED Safety and Feasibility of PD-1 Blockade in the Treatment of dMMR or MSI-H Rectal Cancer
Case Comprehensive Cancer Center
NCT02834611 COMPLETED Ceramide NanoLiposome in Patients With Advanced Solid Tumors
Keystone Nano, Inc
NCT05631327 TERMINATED A JZP341 Study in Adult Participants With Advanced or Metastatic Solid Tumors
Jazz Pharmaceuticals
NCT03199040 TERMINATED Neoantigen DNA Vaccine Alone vs. Neoantigen DNA Vaccine Plus Durvalumab in Triple Negative Breast Cancer Patients Following Standard of Care Therapy
Washington University School of Medicine
NCT03666273 COMPLETED Phase 1 Study of BAY1905254 - An Early Clinical Research Study to Evaluate a New Drug Called Bapotulimab (BAY1905254) in the Expansion Cohort in Combination With Pembrolizumab in Head and Neck Cancer That Has Returned or is Discovered to be Metastatic and is Expressing PDL1.
Bayer
NCT05508100 COMPLETED Dose Confirmation and Dose Expansion Phase 1 Study of IO-108 and IO-108 + Anti-PD-1 in Solid Tumors
Immune-Onc Therapeutics
NCT03629756 COMPLETED A Study to Evaluate the Safety and Tolerability of Immunotherapy Combinations in Participants With Advanced Malignancies
Arcus Biosciences, Inc.
NCT03720678 COMPLETED A Study to Evaluate Immunotherapy Combinations in Participants With Gastrointestinal Malignancies
Arcus Biosciences, Inc.
NCT04400383 COMPLETED Clinical Trial to Evaluate AB011 Injection in Patients With CLDN18.2-positive Advanced Solid Tumors
CARsgen Therapeutics Co., Ltd.
NCT04190628 TERMINATED Safety and Tolerability of ABM-1310 in Patients With Advanced Solid Tumors
ABM Therapeutics Corporation
NCT03238027 COMPLETED A Phase 1 Study to Investigate Axatilimab Alone or in Combination With Durvalumab in Patients With Solid Tumors
Syndax Pharmaceuticals
NCT02663518 TERMINATED A Trial of PF-07901800 (TTI-621) for Patients With Hematologic Malignancies and Selected Solid Tumors
Pfizer
NCT04887194 COMPLETED PK Study to Assess Drug-drug Interaction and QTc Between Sitravatinib and a Cocktail of Substrates
Mirati Therapeutics Inc.
NCT02261285 COMPLETED ONO-4538 Phase I Study in Patients With Solid Tumor
Ono Pharmaceutical Co., Ltd.
NCT04250597 TERMINATED Study of GNX102 in Patients With Advanced Solid Tumors
GlycoNex, Inc.
NCT02261298 COMPLETED ONO-4538 Phase I Study in Patients With Solid Tumor
Ono Pharmaceutical Co., Ltd.
NCT01832116 COMPLETED 89Zr-MMOT PET Imaging in Pancreatic and Ovarian Cancer Patients
University Medical Center Groningen
NCT02760199 COMPLETED 89Zr-AMG211 PET Imaging Study
University Medical Center Groningen
NCT02517398 COMPLETED MSB0011359C (M7824) in Metastatic or Locally Advanced Solid Tumors
EMD Serono Research & Development Institute, Inc.
NCT04403308 COMPLETED ONO-7913 Phase I Study (ONO-7913)
Ono Pharmaceutical Co., Ltd.
NCT05309512 TERMINATED Clinical Study of KN052 in Chinese Subjects With Advanced Solid Tumors
Jiangsu Alphamab Biopharmaceuticals Co., Ltd
NCT04281420 TERMINATED A Study of Evaluating Dual Inhibitor of PAK4 and NAMPT ATG-019 in Advanced Solid Tumors or Non-Hodgkin's Lymphoma
Antengene Therapeutics Limited
NCT03874897 COMPLETED Chimeric Antigen Receptor T Cells Targeting claudin18.2 in Solid Tumors.
Peking University
NCT04873895 TERMINATED TACE Plus Axitinib and Hydroxychlorquine for Liver-Dominant Metastatic Colorectal Cancer (CRC)
Abramson Cancer Center at Penn Medicine
NCT01279291 TERMINATED Study of Anti-HB-EGF Antibody KHK2866 in Subjects With Advanced Solid Tumors and Ovarian Cancer
Kyowa Kirin Co., Ltd.
NCT02867007 COMPLETED KHK2455 Alone and in Combination With Mogamulizumab in Subjects With Locally Advanced or Metastatic Solid Tumors
Kyowa Kirin, Inc.
NCT05173792 COMPLETED Study of AK119 in Subjects With Advanced Solid Tumors
Akeso
NCT00921336 COMPLETED Safety Study to Evaluate KW-2450 in Subjects With Advanced Solid Tumor
Kyowa Kirin Co., Ltd.
NCT02301130 COMPLETED Study of Mogamulizumab + MEDI4736 (Durvalumab) and Mogamulizumab + Tremelimumab in Subjects w/ Advanced Solid Tumors
Kyowa Kirin, Inc.
NCT05152212 COMPLETED Study of LVGN7409 (CD40 Agonist Antibody) in Locally Advanced, Metastatic or Recurrent/Refractory Malignancy
Lyvgen Biopharma Holdings Limited
NCT03650348 COMPLETED PRS-343 in Combination With Atezolizumab in HER2-Positive Solid Tumors
Pieris Pharmaceuticals, Inc.
NCT03330561 COMPLETED PRS-343 in HER2-Positive Solid Tumors
Pieris Pharmaceuticals, Inc.
NCT04694781 COMPLETED Study of LVGN6051 (CD137 Agonist Antibody) in Advanced or Metastatic Malignancy
Lyvgen Biopharma Holdings Limited
NCT05376202 COMPLETED Image Guided Penile Cancer Surgery
University Medical Center Groningen
NCT04349280 TERMINATED A Study to Evaluate the Efficacy and Safety of Bintrafusp Alfa (M7824) Monotherapy in Metastatic or Locally Advanced Urothelial Cancer
GlaxoSmithKline
NCT05518201 COMPLETED Evaluate the Safety and Immunogenicity of a 9-valent HPV Vaccine in Chinese Healthy Male Aged 9-45 Year-old
Shanghai Bovax Biotechnology Co., Ltd.
NCT05678283 WITHDRAWN A Study of Absorption, Metabolism, and Elimination CC-90010 in Participants With Advanced Solid Tumors
Bristol-Myers Squibb
NCT05001516 COMPLETED Study of Turning Point Therapeutics LM-302 in Patients With Advance Solid Tumors
Turning Point Therapeutics, Inc.
NCT06372223 COMPLETED A Food Effect Study of SPH5030 Tablets.
Shanghai Pharmaceuticals Holding Co., Ltd
NCT04059588 COMPLETED A Study Investigating the Safety and Tolerability of an Immune Treatment in Cancer Patients With Lesions to the Skin
Rockefeller University
NCT02516553 COMPLETED BI 894999 First in Human Dose Finding Study in Advanced Malignancies
Boehringer Ingelheim
NCT04306224 COMPLETED A Study of IMC-002 in Subjects With Metastatic or Locally Advanced Solid Tumors and Relapsed or Refractory Lymphomas
ImmuneOncia Therapeutics Inc.
NCT05061537 TERMINATED Study of PF-07263689 in Participants With Selected Advanced Solid Tumors
Pfizer
NCT03250832 COMPLETED Study of TSR-033 With an Anti-programmed Cell Death-1 Receptor (PD-1) in Participants With Advanced Solid Tumors
Tesaro, Inc.
NCT04714983 SUSPENDED DNX-2440 for Resectable Colorectal Liver Metastasis
DNAtrix, Inc.
NCT04040699 COMPLETED KN026 Combined With KN046 in Subjects With HER2 Positive Solid Tumor
Peking University
NCT04557306 COMPLETED Evaluationn of Tolerability and Safety of CBT101, an Autologous Natural Killer Cell, in Patients With Solid Cancer
CHABiotech CO., Ltd
NCT03490669 COMPLETED Study to Evaluate Safety, PK, PD, Immunogenicity & Antitumor Activity of MSC-1 in Patients With Adv Solid Tumors
AstraZeneca
NCT04148937 COMPLETED A Study of the CD73 Inhibitor LY3475070 Alone or in Combination With Pembrolizumab in Participants With Advanced Cancer
Eli Lilly and Company
NCT03206021 COMPLETED COZMOS:Phase I/Ib Trial of Combined 5'Azacitidine and Carboplatin for Recurrent/Refractory Pediatric Brain/Solid Tumors
The Hospital for Sick Children
NCT06219499 WITHDRAWN Safety, Tolerability, Immunogenicity and Pharmacokinetics of ONC-841
OncoC4, Inc.
NCT04095273 COMPLETED Study to Test How Well Patients With Advanced Solid Tumors Respond to Treatment With the Elimusertib in Combination With Pembrolizumab, to Find the Optimal Dose for Patients, How the Drug is Tolerated and the Way the Body Absorbs, Distributes and Discharges the Drug
Bayer
NCT06137651 WITHDRAWN Trotabresib in Combination With Vinorelbine and Radiation Therapy for the Treatment of HER2+ Breast Cancer With Central Nervous System or Leptomeningeal Metastasis
Northwestern University
NCT03329950 COMPLETED A Study of CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced Malignancies
Celldex Therapeutics
NCT04901806 TERMINATED Study of PBI-200 in Subjects With NTRK-Fusion-Positive Solid Tumors
Pyramid Biosciences
NCT05128539 TERMINATED A Study Explore JS001+JS002 in Patients With Advanced Cancer
Shanghai Junshi Bioscience Co., Ltd.
NCT03590054 COMPLETED Abexinostat in Combination With Pembrolizumab in Patients With Advanced Solid Tumor Malignancies
Rahul Aggarwal
NCT04691375 TERMINATED A Study of PY314 in Subjects With Advanced Solid Tumors
Ikena Oncology
NCT04682431 TERMINATED A Phase 1a/1b FIH Study of PY159 and in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors
Ikena Oncology
NCT03010982 COMPLETED Open-Label, Multi-Center, Two-Part, Ph1 Study to Characterize the PKs of an Intravenous Micro-Dose of [14C]-Tazemetostat (EPZ 6438) and the ADME of an Oral [14C]-Labeled Dose of Tazemetostat in Subjects With B-Cell Lymphomas or Adv Solid Tumors
Epizyme, Inc.
NCT04586335 TERMINATED Study of CYH33 in Combination With Olaparib an Oral PARP Inhibitor in Patients With Advanced Solid Tumors.
Haihe Biopharma Co., Ltd.
NCT01621854 COMPLETED NUC-1031 in Patients With Advanced Solid Tumours
Imperial College London
NCT02022982 COMPLETED PALBOCICLIB + PD-0325901 for NSCLC & Solid Tumors
Dana-Farber Cancer Institute
NCT04200963 COMPLETED A Phase 1a/b Study of IK-175 as a Single Agent and in Combination With Nivolumab in Patients With Locally Advanced or Metastatic Solid Tumors and Urothelial Carcinoma
Ikena Oncology
NCT05472506 WITHDRAWN Oral AHR Antagonist in Combination With Nivolumab in Patients With PD-1 Resistant Metastatic or Recurrent Head and Neck Cancer
Ikena Oncology
NCT04761601 TERMINATED First in Human Study of UCT-01-097 in Participants With Advanced Solid Tumors
1200 Pharma, LLC
NCT05231746 COMPLETED A Study of hSTC810 With Advanced/Metastatic Solid Tumors (STCUBE-001)
STCube, Inc.
NCT04914351 COMPLETED HY-0102 Monotherapy in Patients With Locally Advanced/Metastatic Solid Tumours
Shanghai HyaMab Biotech Co.,Ltd.
NCT05547906 COMPLETED Evaluation of the Safety and Efficacy of ASCA101 in Patients With Advanced Solid Tumors
MetaFines
NCT04430348 TERMINATED PTX-35 in Patients With Advanced Solid Tumors
Pelican Therapeutics, Inc.
NCT01409135 COMPLETED A Study of the Safety and Pharmacokinetics of AGS-22M6E in Subjects With Malignant Solid Tumors That Express Nectin-4
Astellas Pharma Inc
NCT05121948 TERMINATED A Study of HC-7366 to Establish the Maximum Tolerated Dose (MTD) and Recommended Phase 2 Dose (RP2D)
HiberCell, Inc.
NCT04834778 COMPLETED A Study of HC-5404-FU to Establish the Maximum Tolerated Dose (MTD)
HiberCell, Inc.
NCT04144140 TERMINATED Study of Intratumorally Administered Stimulator of Interferon Genes (STING) Agonist E7766 in Participants With Advanced Solid Tumors or Lymphomas - INSTAL-101
Eisai Inc.
NCT01286467 COMPLETED A Study Of PF-04449913 Administered Alone In Select Solid Tumors
Pfizer
NCT04069026 COMPLETED A First-in-Humans Dose Finding Study for an Aryl Hydrocarbon Receptor Inhibitor (AhRi) in Patients With Advanced Cancer
Bayer
NCT05496595 TERMINATED DCBY02 as a Monotherapy in Patients With Advanced or Metastatic Solid Tumors
DynamiCure Biotechnology
NCT03604445 TERMINATED This Study Aims to Find and Test a Safe Dose of BI 905677 in Patients With Different Types of Cancer (Solid Tumours)
Boehringer Ingelheim
NCT03705351 TERMINATED Tumor Treating Fields With Chemoradiation in Newly Diagnosed GBM
Providence Health & Services
NCT04158583 TERMINATED A Study to Evaluate the Safety and Tolerability of RO7296682 in Participants With Advanced Solid Tumors
Hoffmann-La Roche
NCT05051241 COMPLETED A Study of GFH018 in Patients With Advanced Solid Tumors
Zhejiang Genfleet Therapeutics Co., Ltd.
NCT04920383 TERMINATED ALPN-202 With PD-1 Inhibition in Advanced Malignancies
Alpine Immune Sciences, Inc.
NCT06198556 COMPLETED Effect of Rifampicin on the Pharmacokinetics of HRS-1167 in Healthy Subjects
Jiangsu HengRui Medicine Co., Ltd.
NCT03343301 COMPLETED A Study of Bemarituzumab (FPA144) Combined With Modified FOLFOX6 in Gastric/Gastroesophageal Cancer
Five Prime Therapeutics, Inc.
NCT05277402 COMPLETED ADG116 in Combination With Pembrolizumab in Patients With Advanced/Metastatic Solid Tumors
Adagene Inc
NCT03523390 COMPLETED Phase I/Ib Multiple Ascending Dose Study in China
Merck KGaA, Darmstadt, Germany
NCT04892043 TERMINATED Study of SQZ-AAC-HPV in Patients With HPV16+ Recurrent, Locally Advanced or Metastatic Solid Tumors
SQZ Biotechnologies
NCT05078593 COMPLETED A Clinical Study to Evaluate the Safety, Tolerability and Pharmacokinetic Characteristics of HLX26 Monoclonal Antibody Injection in Patients With Solid Tumor or Lymphoma
Shanghai Henlius Biotech
NCT05248074 COMPLETED To Evaluate the Safety, Pharmacokinetic and the Effect of Food After Administration of ABN401 in Healthy Adult Volunteers
Abion Inc
NCT05498480 COMPLETED Study of Relatlimab in Combination With Nivolumab in Chinese Participants
Bristol-Myers Squibb
NCT03345784 TERMINATED Testing AZD1775 inC Combination With Radiotherapy and Chemotherapy in Cervical, Upper Vaginal and Uterine Cancers
National Cancer Institute (NCI)
NCT03728179 COMPLETED RACIN in Patients With Advanced TIL-negative Solid Tumors
Centre Hospitalier Universitaire Vaudois
NCT04341311 TERMINATED Phase I Study of Marizomib + Panobinostat for Children With DIPG
Dana-Farber Cancer Institute
NCT03516214 COMPLETED EGF816 and Trametinib in Patients With Non-small Cell Lung Cancer Harboring Activating EGFR Mutations
University of Cologne
NCT05408871 TERMINATED Non-invasive Measurement of PD-L1 Levels With Positron Emission Tomography (PET) in Head and Neck Malignancies and Intracranial Metastases
Yale University
NCT02723240 COMPLETED NUC-3373 in Advanced Solid Tumours
University of Oxford
NCT03964259 COMPLETED Reduced IV Fluids to Improve Clearance of HDMTX in Children w/Lymphoma or Acute Lymphoblastic Leukemia
Virginia Commonwealth University
NCT00930332 TERMINATED Methadone Hydrochloride as First-Line Therapy in Treating Patients With Chronic Neuropathic Cancer Pain
NCIC Clinical Trials Group
NCT05641324 TERMINATED A Study of ANV419 Alone or in Combination With Approved Treatments in Patients With Multiple Myeloma (OMNIA-2)
Anaveon AG
NCT04842630 TERMINATED A Phase 1 Dose Escalation and Expansion Study Of SHR-1916 In Subjects With Locally Advanced Or Metastatic Solid Tumors
Jiangsu HengRui Medicine Co., Ltd.
NCT04921878 COMPLETED A Study of Mitoxantrone Hydrochloride Liposome Injection in Chinese Patients With Advanced Solid Tumors
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
NCT04675996 TERMINATED First-in-Human Study of INT-1B3 in Patients With Advanced Solid Tumors
InteRNA
NCT05400265 COMPLETED Evaluate the Safety, Tolerability, Pharmacokinetic Characteristics and Preliminary Efficacy of HLX26 and HLX10 in Patients With Advanced/Metastatic Solid Tumor
Shanghai Henlius Biotech
NCT03209401 TERMINATED Niraparib Plus Carboplatin in Patients With Homologous Recombination Deficient Advanced Solid Tumor Malignancies
Georgetown University
NCT04857138 COMPLETED A Study to Evaluate Safety, Pharmacokinetics and Anti-Tumor Activity of RO7300490, as Single Agent or in Combination With Atezolizumab in Participants With Advanced Solid Tumors
Hoffmann-La Roche
NCT04074343 COMPLETED TAS-102 and Irinotecan in 2L+ Gastric and Gastroesophageal Adenocarcinoma
University of California, Irvine
NCT03255070 COMPLETED A Dose-escalation, Expansion Study of ARX788, in Advanced Solid Tumors Subjects With HER2 Expression (ACE-Pan Tumor 01)
Ambrx, Inc.
NCT04862767 COMPLETED TASO-001 in Combination With Recombinant Interleukin-2(Aldesleukin) in Advanced or Metastatic Solid Tumor
Autotelicbio
NCT03012230 COMPLETED Pembrolizumab and Ruxolitinib Phosphate in Treating Patients With Metastatic Stage IV Triple Negative Breast Cancer
Mayo Clinic
NCT05099536 WITHDRAWN 3D011-08 Monotherapy in Subjects With Advanced Solid Tumors
3D Medicines (Beijing) Co., Ltd.
NCT04564417 TERMINATED First-In-Human (FIH) Study of W0180 as Single Agent and in Combination With Pembrolizumab in Adults With Locally Advanced or Metastatic Solid Tumors
Pierre Fabre Medicament
NCT04609579 TERMINATED Study of SNX281 in Subjects With Advanced Solid Tumors and Lymphoma
Stingthera, Inc.
NCT02828098 COMPLETED Exploratory Study of BO-112 in Adult Patients With Aggressive Solid Tumors
Highlight Therapeutics
NCT04025216 TERMINATED A Study of CART-TnMUC1 in Patients With TnMUC1-Positive Advanced Cancers
Kite, A Gilead Company
NCT05848843 WITHDRAWN A Phase I Study of Adagrasib and Durvalumab for Treatment of Advanced Non-small Cell Lung Cancers and Gastro-intestinal Cancers Harboring KRAS G12C Mutations
M.D. Anderson Cancer Center
NCT02564900 COMPLETED Study of DS-8201a in Subjects With Advanced Solid Malignant Tumors
Daiichi Sankyo Co., Ltd.
NCT02457845 COMPLETED HSV G207 Alone or With a Single Radiation Dose in Children With Progressive or Recurrent Supratentorial Brain Tumors
Gregory K. Friedman, MD
NCT01954316 COMPLETED A Study of CFI-400945 Fumarate in Patients With Advanced Cancer
University Health Network, Toronto
NCT05002140 COMPLETED Trial of XRD-0394, a Kinase Inhibitor, in Combination With Palliative Radiotherapy in Advanced Cancer Patients
XRad Therapeutics Inc
NCT04235101 COMPLETED Phase I Study of SYD985 With Niraparib in Patients With Solid Tumors
Byondis B.V.
NCT06165809 WITHDRAWN A Clinical Trial of TQB3015 Tablets in Patients With Advanced Malignant Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT01825603 COMPLETED ADH-1, Gemcitabine Hydrochloride & Cisplatin in Treating Metastatic Pancreatic or Biliary Tract Cancer
University of Nebraska
NCT04483505 COMPLETED Rogaratinib, Palbociclib y Fulvestrant in Patients With Breast Cancer.
Fundacion CRIS de Investigación para Vencer el Cáncer
NCT04187872 TERMINATED LITT and Pembrolizumab in Recurrent Brain Metastasis
University of Florida
NCT03912831 TERMINATED Study to Evaluate the Safety and Efficacy of KITE-439 in HLA-A*02:01+ Adults With Relapsed/Refractory HPV16+ Cancers
Gilead Sciences
NCT05930457 COMPLETED Study of 64Cu-FAPI-XT117 PET/CT in Patients With Malignant Solid Tumors
The First Affiliated Hospital of Guangzhou Medical University
NCT01206465 COMPLETED Pralatrexate and Fluorouracil in Treating Patients With Recurrent Solid Tumors
University of Nebraska
NCT03219268 COMPLETED A Study of MGD013 in Patients With Unresectable or Metastatic Neoplasms
MacroGenics
NCT03565367 COMPLETED Hyperpolarized Carbon C 13 Pyruvate Magnetic Resonance Spectroscopic Imaging in Detecting Lactate and Bicarbonate in Participants With Central Nervous System Tumors
Daniel M. Spielman
NCT04096716 TERMINATED Mapping Draining Lymph Nodes in CNS Malignancies
Washington University School of Medicine
NCT04267939 TERMINATED ATR Inhibitor Elimusertib (BAY1895344) Plus Niraparib Phase 1b Study in Advanced Solid Tumors and Ovarian Cancer
Bayer
NCT00782574 COMPLETED Phase I AZD2281/Cisplatin in Advanced Solid Tumour Patients
AstraZeneca
NCT03454451 COMPLETED CPI-006 Alone and in Combination With Ciforadenant and With Pembrolizumab for Patients With Advanced Cancers
Corvus Pharmaceuticals, Inc.
NCT02482168 COMPLETED Study of the CD40 Agonistic Monoclonal Antibody APX005M
Apexigen America, Inc.
NCT05814835 COMPLETED First in Human Study of 68Ga/64Cu-FAPI-XT117 PET/CT in Patients With Malignant Solid Tumors
Chinese PLA General Hospital
NCT04944888 COMPLETED GSL Synthetase Inhibitor in Combination With Immune Checkpoint Inhibitor in Previously Treated Blood and Solid Tumor
Chinese PLA General Hospital
NCT03463473 COMPLETED A Phase I Study of MSB2311 in Advanced Solid Tumors
Suzhou Transcenta Therapeutics Co., Ltd.
NCT04272944 COMPLETED A Study of MSB2311 in Advanced Solid Tumors
Suzhou Transcenta Therapeutics Co., Ltd.
NCT04033328 TERMINATED Study of ORIC-101 in Combination With Enzalutamide
ORIC Pharmaceuticals
NCT03928314 TERMINATED Study of ORIC-101 in Combination With Anticancer Therapy
ORIC Pharmaceuticals
NCT01946074 COMPLETED A Study of ABT-165 in Subjects With Solid Tumors
AbbVie
NCT05490381 WITHDRAWN Preoperative Embolization of Hypervascular Head and Neck Tumors to Improve Surgical Outcomes
University of Washington
NCT03525392 TERMINATED Study to Evaluate the Safety and Activity (Including Distribution) of 177Lu-3BP-227 in Subjects With Solid Tumours Expressing Neurotensin Receptor Type 1.
Ipsen
NCT05800249 COMPLETED PE0116 Injection in Treatment of Patients With Advanced Solid Tumours
Shanghai HyaMab Biotech Co.,Ltd.
NCT05861778 COMPLETED Evaluation of 89Zr-TLX250 PET/CT in Chinese Patients With Indeterminate Renal Masses or Suspected Recurrent Renal Clear Cell Carcinoma
Telix Pharmaceuticals (Innovations) Pty Limited
NCT05159518 COMPLETED A Study of PRT2527 in Participants With Advanced Solid Tumors
Prelude Therapeutics
NCT04513067 TERMINATED A Safety Study of YQ23 in Advanced Solid Tumors Patients
New Beta Innovation Limited
NCT03229278 COMPLETED Trigriluzole With Nivolumab and Pembrolizumab in Treating Patients With Metastatic or Unresectable Solid Malignancies or Lymphoma
Rutgers, The State University of New Jersey
NCT03131765 COMPLETED Dose Escalation and Cohort Expansion Study of YS-ON-001 in Patients With Advanced Solid Tumors
Yisheng Biopharma (Singapore) Pte. Ltd.
NCT02193347 COMPLETED IDH1 Peptide Vaccine for Recurrent Grade II Glioma
Katy Peters, MD, PhD
NCT03861403 TERMINATED A Dose Escalation and Expansion Study of TRX518 in Combination With Cyclophosphamide Plus Avelumab in Advanced Solid Tumors
Leap Therapeutics, Inc.
NCT04892875 WITHDRAWN A Study of Concurrent Chemoradiation in Combination With or Without PD1 Inhibitor AB122 Adenosine 2a Receptor / Adenosine 2b Receptor Inhibitor AB928 Therapies in Locally Advanced Head and Neck Cancers
Jennifer Choe
NCT05644626 WITHDRAWN Safety, Pharmacokinetics and Antitumor Activity of BGB-B167 Alone and in Combination With Tislelizumab in Participants With Solid Tumors in Chinese Participants
BeiGene
NCT04147247 COMPLETED A Trial to Find the Safe Dose for BI 905681 in Patients With Incurable Tumours or Tumours That Have Spread
Boehringer Ingelheim
NCT05791474 WITHDRAWN ATI-2231 in Advanced Solid Tumor Malignancies
Washington University School of Medicine
NCT04473716 COMPLETED Neoadjuvant Toripalimab and Paclitaxel/Cisplatin on Pathological Response in Oral Squamous Cell Carcinoma Patients
Shanghai Jiao Tong University School of Medicine
NCT03225105 TERMINATED M3541 in Combination With Radiotherapy in Solid Tumors
EMD Serono Research & Development Institute, Inc.
NCT04393506 COMPLETED Inductive Camrelizumab and Apatinib for Patients With Locally Advanced and Resectable Oral Squamous Cell Carcinoma
Shanghai Jiao Tong University School of Medicine
NCT02693080 COMPLETED CT Perfusion Imaging in Predicting Treatment Response in Patients With Non-small Cell Lung Cancer or Lung Metastases Treated With Stereotactic Ablative Radiation Therapy
Stanford University
NCT03954704 TERMINATED Study of Dalutrafusp Alfa (Formerly GS-1423) in Participants With Advanced Solid Tumors
Gilead Sciences
NCT04830501 COMPLETED Study of the of the Safety and Tolerability of TT-00434 in Patients With Advanced Solid Tumors
TransThera Sciences (Nanjing), Inc.
NCT04602117 WITHDRAWN ISPY-P1.01:Evaluating the Safety of Weekly Paclitaxel With Trastuzumab Duocarmazine (SYD985) in Patients With Metastatic Cancer
QuantumLeap Healthcare Collaborative
NCT05017623 COMPLETED A Study to Evaluate YH003 in Subjects With Advanced Solid Tumors
Eucure (Beijing) Biopharma Co., Ltd
NCT03810742 COMPLETED Nanoliposomal Irinotecan (Nal-IRI, ONIVYDE®) in Combination With TAS-102 (LONSURF®) in Refractory Solid Tumors
PharmaEngine
NCT02467361 COMPLETED A Study of BBI608 Administered in Combination With Immune Checkpoint Inhibitors in Adult Patients With Advanced Cancers
Sumitomo Pharma America, Inc.
NCT01781455 COMPLETED A Study of BBI503 in Adult Patients With Advanced Solid Tumors
Sumitomo Pharma America, Inc.
NCT01775423 COMPLETED A Study of BBI608 in Adult Patients With Advanced Malignancies
Sumitomo Pharma America, Inc.
NCT03429218 COMPLETED First-in-human Study of Oral TP-0184 in Patients With Advanced Solid Tumors
Sumitomo Pharma America, Inc.
NCT02729298 COMPLETED First-in-human Study of Oral TP-0903 (a Novel Inhibitor of AXL Kinase) in Patients With Advanced Solid Tumors
Sumitomo Pharma America, Inc.
NCT03715504 COMPLETED Study of TP-3654 in Patients With Advanced Solid Tumors
Sumitomo Pharma America, Inc.
NCT02483247 COMPLETED A Study of BBI503 in Combination With Selected Anti-Cancer Therapeutics in Adult Patients With Advanced Cancer
Sumitomo Pharma America, Inc.
NCT03416816 TERMINATED A Study of DSP-0337 in Patients With Advanced Solid Tumors to Determine the Safety and the Pharmacokinetic Profile
Sumitomo Pharma America, Inc.
NCT03941262 COMPLETED Safety of SNK01 in Subjects With Pathologically Confirmed Metastatic and/or Unresectable Cancer Refractory to Conventional Therapy
NKGen Biotech, Inc.
NCT02834780 COMPLETED Phase 1 Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of H3B-6527 in Participants With Advanced Hepatocellular Carcinoma
H3 Biomedicine Inc.
NCT05369221 COMPLETED Feasibility of ReSpace™ Hydrogel to Establish a Stable Cervical-rectal Space
Peking Union Medical College Hospital
NCT04630522 COMPLETED Efficacy and Safety of JMT103 in Patients With Bone Metastases From Solid Tumors
Shanghai JMT-Bio Inc.
NCT05905341 WITHDRAWN Study of PF-07224826, as a Single Agent or in Combination With Endocrine Therapy in Participants With Breast Cancer and Other Advanced Solid Tumors.
Pfizer
NCT02432326 COMPLETED A Study of BBI608 and BBI503 Administered in Combination to Adult Patients With Advanced Solid Tumors
Sumitomo Pharma America, Inc.
NCT05221385 TERMINATED Gentulizumab in Patients With Advanced Solid Malignancies and Non-Hodgkin Lymphoma
Changchun GeneScience Pharmaceutical Co., Ltd.
NCT03304210 COMPLETED PIPAC Nab-pac for Stomach, Pancreas, Breast and Ovarian Cancer
University Hospital, Ghent
NCT04337853 COMPLETED Radiotherapy of Tongue Cancer Using an Intraoral Stent
Oslo University Hospital
NCT02616185 TERMINATED A Phase 1 Study To Evaluate Escalating Doses Of A Vaccine-Based Immunotherapy Regimen For Prostate Cancer (PrCa VBIR)
Pfizer
NCT03240861 TERMINATED Genetically Engineered PBMC and PBSC Expressing NY-ESO-1 TCR After a Myeloablative Conditioning Regimen to Treat Patients With Advanced Cancer
Jonsson Comprehensive Cancer Center
NCT01099644 TERMINATED Intraperitoneal RIT With 131I-8H9 for Pts With DSRCT and Other Solid Tumors Involving the Peritoneum
Y-mAbs Therapeutics
NCT02054806 COMPLETED Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-028/KEYNOTE-28)
Merck Sharp & Dohme LLC
NCT04475523 COMPLETED Phase 1 Study of CI-8993 Anti-VISTA Antibody in Patients With Advanced Solid Tumor Malignancies
Curis, Inc.
NCT04247126 COMPLETED A Study of SY 5609, a Selective CDK7 Inhibitor, in Advanced Solid Tumors
Syros Pharmaceuticals
NCT02644460 COMPLETED Abemaciclib in Children With DIPG or Recurrent/Refractory Solid Tumors
Emory University
NCT04162327 COMPLETED A Phase Ia/Ib Study of IBI315 in Patients With HER2-expressing Advanced Solid Tumor
Innovent Biologics (Suzhou) Co. Ltd.
NCT04958434 TERMINATED Study of TST005 in Patients With Locally Advanced or Metastatic Solid Tumors
Suzhou Transcenta Therapeutics Co., Ltd.
NCT05600582 WITHDRAWN A Study of CodaLytic, an Intratumoral Oncolytic Virus, in Patients With Breast Cancer
Codagenix, Inc
NCT01332682 COMPLETED Resistance Training and Physical Functioning in Head and Neck Cancer Patients
University of Alabama at Birmingham
NCT03099109 COMPLETED A Study of LY3321367 Alone or With LY3300054 in Participants With Advanced Relapsed/Refractory Solid Tumors
Eli Lilly and Company
NCT04404140 TERMINATED A Study Evaluating The Safety, Efficacy and Pharmacokinetics Of Ipatasertib In Combination With Atezolizumab And Docetaxel In Metastatic Castration-Resistant Prostate Cancer (mCRPC).
Hoffmann-La Roche
NCT02718911 COMPLETED A Study of LY3022855 in Combination With Durvalumab or Tremelimumab in Participants With Advanced Solid Tumors
Eli Lilly and Company
NCT03690154 TERMINATED A Phase 1 Study to Evaluate FN-1501 Monotherapy in Patients With Advanced Solid Tumors and R/R AML
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.
NCT04598321 TERMINATED BrUOG 390: Neoadjuvant Treatment With Talazoparib
Brown University
NCT05073484 TERMINATED Assessment of Safety and Preliminary Efficacy With BAT6021 in Solid Tumor Patients
Bio-Thera Solutions
NCT03188965 COMPLETED First-in-human Study of ATR Inhibitor BAY1895344 in Patients With Advanced Solid Tumors and Lymphomas
Bayer
NCT05120375 TERMINATED Assessment of Safety and Preliminary Efficacy With BAT6021 in Solid Tumor Patients in China
Bio-Thera Solutions
NCT03122106 TERMINATED Neoantigen DNA Vaccine in Pancreatic Cancer Patients Following Surgical Resection and Adjuvant Chemotherapy
Washington University School of Medicine
NCT04635631 COMPLETED STUDY OF TALAZOPARIB MONOTHERAPY IN CHINESE PARTICIPANTS WITH ADVANCED SOLID TUMORS
Pfizer
NCT02897375 COMPLETED Palbociclib With Cisplatin or Carboplatin in Advanced Solid Tumors
Emory University
NCT00993044 COMPLETED A Study of Vincristine, Escalating Doses of Irinotecan, Temozolomide and Bevacizumab (Vit-b) in Pediatric and Adolescent Patients With Recurrent or Refractory Solid Tumors of Non-hematopoietic Origin
Children's Hospital Los Angeles
NCT03730337 COMPLETED Phase 1 Study of ONO-7475 With and Without ONO-4538 in Subjects Advanced or Metastatic Solid Tumors
Ono Pharmaceutical Co., Ltd.
NCT00803569 COMPLETED Vaccine Therapy in Stage II, III, or IV Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancers
Ludwig Institute for Cancer Research
NCT01632436 WITHDRAWN Pharmacokinetic and Safety Study of Pixantrone in Patients With Metastatic Cancer and Hepatic Impairment
CTI BioPharma
NCT05828277 WITHDRAWN A Phase 1 Study to Assess the Effect of Hepatic Impairment on the Pharmacokinetics of Repotrectinib in Advanced Cancer Patients
Turning Point Therapeutics, Inc.
NCT02793466 COMPLETED Durvalumab in Pediatric and Adolescent Patients
Leo Mascarenhas
NCT03859752 SUSPENDED TR1801-ADC in Patients With Tumors That Express c-Met
Open Innovation Partners, Inc.
NCT05395052 TERMINATED FT536 Monotherapy and in Combination With Monoclonal Antibodies in Advanced Solid Tumors
Fate Therapeutics
NCT00648648 COMPLETED A Dose Escalation Study of Adavosertib (MK-1775) in Combination With Either Gemcitabine, Cisplatin, or Carboplatin in Adults With Advanced Solid Tumors (MK-1775-001)
Merck Sharp & Dohme LLC
NCT04551885 TERMINATED FT516 in Combination With Monoclonal Antibodies in Advanced Solid Tumors
Fate Therapeutics
NCT05069935 TERMINATED FT538 in Combination With Monoclonal Antibodies in Advanced Solid Tumors
Fate Therapeutics
NCT05698888 TERMINATED Study of VP301 in Patients With Multiple Myeloma, Lymphoma, or Solid Tumors
Virtuoso BINco, Inc.
NCT04865159 TERMINATED Cardiovascular Safety Study of Tipifarnib in Patients With Advanced Solid Malignancies
Kura Oncology, Inc.
NCT05921916 COMPLETED Study to Assess the Safety and Tolerability of MBF-118 in Healthy Volunteers
Medibiofarma S.L.
NCT01047007 TERMINATED A Dose Escalation Study of Adavosertib(MK1775) in Combination With 5-FU or 5-FU/CDDP in Patients With Advanced Solid Tumor (1775-005
Merck Sharp & Dohme LLC
NCT05144334 TERMINATED A Study of BTX-1188 in Subjects With Advanced Malignancies
Biotheryx, Inc.
NCT04729205 TERMINATED Assessment of Safety and Therapeutic Efficacy of Promitil in Combination With Folfox in Patients With GI Malignancies
Lipomedix Pharmaceuticals Inc.
NCT03714958 COMPLETED Trametinib + HDM201 in CRC Patients With RAS/RAF Mutant and TP53 Wild-type Advanced/Metastatic Colorectal Cancer Mutant and TP53 Wild-type
Centre Leon Berard
NCT04628988 COMPLETED A Study of CC-90011 and Comparators in Participants With Prostate Cancer
Celgene
NCT03452332 COMPLETED Stereotactic Body Radiation Therapy, Tremelimumab and Durvalumab in Treating Participants With Recurrent or Metastatic Cervical, Vaginal, or Vulvar Cancers
M.D. Anderson Cancer Center
NCT04357756 COMPLETED A Study to Assess YH001 in Combination With Toripalimab Injection in Subjects With Advanced Solid Tumors
Eucure (Beijing) Biopharma Co., Ltd
NCT03109041 COMPLETED Initial Feasibility Study to Treat Resectable Pancreatic Cancer With a Planar LDR Source
CivaTech Oncology
NCT05040932 COMPLETED Study of YH004 (4-1BB Agonist Antibody) in Advanced or Metastatic Malignancy
Eucure (Beijing) Biopharma Co., Ltd
NCT04912466 COMPLETED IBI322 Monotherapy or Combination Therapy in Subjects With Advanced Malignant Tumors.
Innovent Biologics (Suzhou) Co. Ltd.
NCT05470933 TERMINATED A Study Explore WJ01075 Tablets in Patients With Advanced Solid Tumors
Suzhou Junjing BioSciences Co., Ltd.
NCT01772563 COMPLETED Investigation of Potential Drug-drug Interaction of Volasertib With Itraconazole in Patients With Various Tumours
Boehringer Ingelheim
NCT02536183 TERMINATED A Phase I Study of Lyso-thermosensitive Liposomal Doxorubicin and MR-HIFU for Pediatric Refractory Solid Tumors
AeRang Kim
NCT03139370 TERMINATED Safety and Efficacy of MAGE-A3/A6 T Cell Receptor Engineered T Cells (KITE-718) in HLA-DPB1*04:01 Positive Adults With Advanced Cancers
Kite, A Gilead Company
NCT04293094 COMPLETED Study of AMG 650 in Adult Participants With Advanced Solid Tumors
Volastra Therapeutics, Inc.
NCT04116710 COMPLETED A Phase 1 Study of HS130 in Combination With Viagenpumatucel-L (HS110) in Patients With Solid Tumors
Heat Biologics
NCT04257617 COMPLETED A Trial of ZL-1201 in Subjects With Advanced Cancer
Zai Lab (Shanghai) Co., Ltd.
NCT02959619 COMPLETED Ensartinib in Non-small Cell Lung Cancer Patients With Positive ALK
Betta Pharmaceuticals Co., Ltd.
NCT03990454 COMPLETED Safety Study of SLC-391 in Subjects With Solid Tumors
SignalChem Lifesciences Corporation
NCT05119998 COMPLETED A Phase I Study of IBI325 in Patients With Advanced Solid Tumor
Innovent Biologics (Suzhou) Co. Ltd.
NCT04467853 TERMINATED A Clinical Study to Evaluate CAR-T Cell-based Medicinal Product in the Treatment of Advanced Solid Tumors
Shanghai East Hospital
NCT04131426 COMPLETED Evaluating the Combined Intervention of Nutritional Supplementation (Remune) and Exercise in Patients With Cancer Cachexia
University of Rochester
NCT03808870 COMPLETED A Safety and Pharmacokinetic Study of NBM-BMX Administered Orally to Asian Patients With Advanced Cancer
NatureWise Biotech & Medicals Corporation
NCT02277717 COMPLETED First-in-human Study With the Antibody-drug Conjugate SYD985 to Evaluate Safety and Efficacy in Cancer Patients
Byondis B.V.
NCT04601402 COMPLETED GEN-001 (Live Biotherapeutic Product) and Avelumab Combination Study for Patients With Solid Tumors Who Have Progressed on Anti-PD-(L)1 Therapy
Genome & Company
NCT02719977 COMPLETED A Phase I Study of CX5461
Canadian Cancer Trials Group
NCT02459301 COMPLETED A Dose-Ranging Study of IPH2201 in Patients With Gynecologic Malignancies
Canadian Cancer Trials Group
NCT05129280 TERMINATED A Study to Evaluate Safety, Pharmacokinetics, and Preliminary Anti-tumor Activity of RO7444973 in Participants With Unresectable and/or Metastatic MAGE-A4-positive Solid Tumors
Hoffmann-La Roche
NCT04214093 TERMINATED A Study of AZD0466 in Patients With Advanced Hematologic or Solid Tumors
AstraZeneca
NCT04034238 COMPLETED Mesothelin-Targeted Immunotoxin LMB-100 in Combination With Tofacitinib in Persons With Previously Treated Pancreatic Adenocarcinoma, Cholangiocarcinoma and Other Mesothelin Expressing Solid Tumors
National Cancer Institute (NCI)
NCT03745989 COMPLETED Study of MK-8353 + Selumetinib in Advanced/Metastatic Solid Tumors (MK-8353-014)
Merck Sharp & Dohme LLC
NCT04585841 COMPLETED The Effect of Cannabidiol on Lean Body Mass in Patients Receiving Chemotherapy
University of Copenhagen
NCT04456140 COMPLETED Pro-Active Genetic Testing in Patients With Solid Tumors, Inherit Study
Mayo Clinic
NCT04541225 TERMINATED Study of NUV-422 in Adults With Recurrent or Refractory High-grade Gliomas and Solid Tumors
Nuvation Bio Inc.
NCT02646852 COMPLETED A Phase I Study of PLX038 in Patients With Advanced Solid Tumors
ProLynx LLC
NCT02503774 COMPLETED MEDI9447 Alone and in Combination With MEDI4736 in Adult Participants With Select Advanced Solid Tumors.
MedImmune LLC
NCT03927573 TERMINATED Study With Bispecific Antibody Engaging T-cells, in Patients With Progressive Cancer Diseases With Positive PSCA Marker
AvenCell Europe GmbH
NCT04695847 COMPLETED M1231 in Participants With Solid Tumors
EMD Serono Research & Development Institute, Inc.
NCT04601285 TERMINATED A Phase I Study of JS108 in Patients With Advanced Solid Tumors
Shanghai Junshi Bioscience Co., Ltd.
NCT03790488 COMPLETED Study of a PD-1 Inhibitor (JTX-4014) in Subjects With Solid Tumor Malignancies
Jounce Therapeutics, Inc.
NCT03829436 COMPLETED TPST-1120 as Monotherapy and in Combination With Nivolumab in Subjects With Advanced Cancers
Tempest Therapeutics
NCT00880074 COMPLETED FLT-PET in Predicting Response to Chemotherapy in Patients With Advanced Malignancies
M.D. Anderson Cancer Center
NCT03028103 COMPLETED Open-Label, Multicenter, Two-Part, Phase 1 Study to Characterize Effects of a Moderate CYP3A Inhibitor on PK of Tazemetostat, Effects of Tazemetostat on PK of CYP2C8 and CYP2C19 Substrates, and Effect of Increased Gastric pH on PK of Tazemetostat in B-cell Lymphoma or Advanced Solid Tumor Patients
Epizyme, Inc.
NCT04914117 COMPLETED A Study of RC118 in Patients With Locally Advanced Unresectable/Metastatic Solid Tumours
RemeGen Co., Ltd.
NCT01029366 COMPLETED CART19 to Treat B-Cell Leukemia or Lymphoma That Are Resistant or Refractory to Chemotherapy
University of Pennsylvania
NCT05913115 COMPLETED A Study Evaluating Safety and Pharmacokinetics of FPA144 in Japanese Patients With Advanced Gastric or Gastroesophageal Cancer
Amgen
NCT01525394 COMPLETED A Double-Blind Study in Healthy Volunteers to Assess the Effect of E7080 on the QTc Interval
Eisai Inc.
NCT01773421 COMPLETED An Open-label, Dose Escalation, Pharmacodynamic, Pharmacokinetic, and Effect of Food Phase 1 Study of E7820 to Determine the Maximum Tolerated Dose Following Twice Daily Oral Administration in Subjects With Unresectable Solid Tumors
Eisai Inc.
NCT01268293 COMPLETED A Study of E7080 in Subjects With Solid Tumor
Eisai Co., Ltd.
NCT05153408 TERMINATED (HARMONY) Study of BLU-701 in EGFR-mutant NSCLC
Blueprint Medicines Corporation
NCT04440943 COMPLETED A Study of the PD-L1xCD27 Bispecific Antibody CDX-527 in Patients With Advanced Malignancies
Celldex Therapeutics
NCT03333031 TERMINATED A Study of HS-196, an HSP90 Inhibitor-linked NIR Probe for Solid Malignancies
Herbert Lyerly
NCT02740712 COMPLETED Pharmacokinetic Drug-Drug Interaction Study of Rucaparib
pharmaand GmbH
NCT03499444 COMPLETED A Study of Rucaparib in Japanese Patients With a Previously-treated Solid Tumor
pharmaand GmbH
NCT02986100 COMPLETED Absorption, Metabolism, and Excretion Following a Single Oral Dose of [14C]-Rucaparib
pharmaand GmbH
NCT03733951 COMPLETED KN046 in Subjects With Advanced Solid Tumors and Lymphoma
Jiangsu Alphamab Biopharmaceuticals Co., Ltd
NCT03521037 COMPLETED Rucaparib Hepatic Impairment Study in Patients With a Solid Tumor
pharmaand GmbH
NCT01009190 COMPLETED A Study Of Poly (ADP-Ribose) Polymerase Inhibitor PF-01367338 In Combination With Several Chemotherapeutic Regimens
pharmaand GmbH
NCT04348916 TERMINATED Study of ONCR-177 Alone and in Combination With PD-1 Blockade in Adult Subjects With Advanced and/or Refractory Cutaneous, Subcutaneous or Metastatic Nodal Solid Tumors or With Liver Metastases of Solid Tumors
Oncorus, Inc.
NCT04989829 COMPLETED Effect of Omeprazole on the Pharmacokinetics of SHR6390 in Healthy Subjects
Jiangsu HengRui Medicine Co., Ltd.
NCT05046808 COMPLETED Pharmacokinetics Study of Famitinib Malate Capsules in Healthy Subjects
Jiangsu HengRui Medicine Co., Ltd.
NCT03954366 COMPLETED Drug-Drug Interaction Study of Rucaparib, Rosuvastatin and Oral Contraceptives
pharmaand GmbH
NCT01430572 COMPLETED Pazopanib and Everolimus in PI3KCA Mutation Positive/PTEN Loss Patients
M.D. Anderson Cancer Center
NCT02583269 COMPLETED Muscadine Grape Skin Extract in Treating Patients With Malignancy That Is Metastatic or Cannot Be Removed by Surgery
Wake Forest University Health Sciences
NCT04186637 TERMINATED An Open-label Study of ALPN-202 in Subjects With Advanced Malignancies
Alpine Immune Sciences, Inc.
NCT03871855 TERMINATED A Study of SHR-1702 Alone or With Camrelizumab in Participants With Advanced Relapsed/Refractory Solid Tumors
Jiangsu HengRui Medicine Co., Ltd.
NCT02333188 COMPLETED Genetic Analysis-Guided Dosing of FOLFIRABRAX in Treating Patients With Advanced Gastrointestinal Cancer
University of Chicago
NCT03311412 COMPLETED Sym021 Monotherapy, in Combination With Sym022 or Sym023, and in Combination With Both Sym022 and Sym023 in Patients With Advanced Solid Tumor Malignancies or Lymphomas
Symphogen A/S
NCT05877651 COMPLETED MASCT-I in Patients With Metastatic or Recurrent Solid Tumors Who Failed Standard Therapy.
HRYZ Biotech Co.
NCT04849273 TERMINATED A Study of TPX-0131, a Novel Oral ALK Tyrosine Kinase Inhibitor, in Patients With ALK+ Advanced or Metastatic NSCLC
Turning Point Therapeutics, Inc.
NCT03536728 COMPLETED Oral AMXT 1501 Dicaprate in Combination With DFMO
Aminex Therapeutics, Inc.
NCT05199519 COMPLETED Study to Evaluate the Safety, Tolerance, Pharmacokinetics and Preliminary Efficacy of IBI345
Innovent Biologics (Suzhou) Co. Ltd.
NCT03892018 TERMINATED The Effect of Food on the Pharmacokinetics of Paclitaxel Administered Orally as Oraxol
Athenex, Inc.
NCT03588039 TERMINATED Study of Oraxol and Pembrolizumab in Subjects With Advanced Solid Tumors
Athenex, Inc.
NCT05774886 WITHDRAWN Implantable Microdevice for TNBC - Pilot Study
Dana-Farber Cancer Institute
NCT05336279 COMPLETED Bioequivalence Study of Famitinib Malate in Healthy Volunteers Under Fasting Condition
Jiangsu HengRui Medicine Co., Ltd.
NCT02351765 COMPLETED ABC-08: Phase Ib Trial of Acelarin in Combination With Cisplatin in Locally Advanced/ Metastatic Biliary Tract Cancers
The Christie NHS Foundation Trust
NCT02961283 TERMINATED Study of ASN003 in Subjects With Advanced Solid Tumors
Asana BioSciences
NCT04341259 COMPLETED A Study Of The Pharmacokinetics And Safety Of Ipatasertib In Chinese Participants With Locally Advanced Or Metastatic Solid Tumors.
Hoffmann-La Roche
NCT02761694 TERMINATED Vevorisertib (ARQ 751) as a Single Agent or in Combination With Other Anti-Cancer Agents, in Solid Tumors With PIK3CA / AKT / PTEN Mutations (MK-4440-001)
ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA)
NCT03310541 COMPLETED AZD5363 in Patients With Advanced Solid Tumors Harboring AKT Mutations
Memorial Sloan Kettering Cancer Center
NCT01912625 TERMINATED Trametinib, Combination Chemotherapy, and Radiation Therapy in Treating Patients With Stage III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery
National Cancer Institute (NCI)
NCT01420874 COMPLETED Anti-CD3 x Anti-Erbitux® Armed Activated T Cells (Phase Ib) for Gastrointestinal (GI Cancer)
Barbara Ann Karmanos Cancer Institute
NCT04184869 COMPLETED Extension Study for Patients Who Had Not Met Criteria for Discontinuation in Previous Sponsored Belinostat Trials
Acrotech Biopharma Inc.
NCT05236049 COMPLETED Use of an Allograft Set-up (SclerFIX) as Replacement of Sclera Graft for Support of Enucleation Implant
TBF Genie Tissulaire
NCT03884517 TERMINATED Clinical Trial of BAT8003 (for Injection) for Patients With Advanced Epithelial Cancer
Bio-Thera Solutions
NCT02376699 TERMINATED Safety Study of SEA-CD40 in Cancer Patients
Seagen Inc.
NCT03841110 COMPLETED FT500 as Monotherapy and in Combination With Immune Checkpoint Inhibitors in Subjects With Advanced Solid Tumors
Fate Therapeutics
NCT04088604 COMPLETED Irinotecan Hydrochloride Liposome Injection (LY01610) For Advanced Solid Tumors
Luye Pharma Group Ltd.
NCT04686383 COMPLETED Safety, Tolerability, and Pharmacokinetics of CAL056 Mesylate in Patients With Resistant or Refractory Solid Tumors
Calgent Biotechnology Co., Ltd
NCT03802955 COMPLETED Study of ADG106 With Advanced or Metastatic Solid Tumors and/or Non-Hodgkin Lymphoma
Adagene (Suzhou) Limited
NCT04144842 COMPLETED Phase 1 Study in Patients With Advanced Solid Malignancies to Evaluate the Safety of ATOR-1017
Alligator Bioscience AB
NCT04650451 SUSPENDED Safety and Activity Study of HER2-Targeted Dual Switch CAR-T Cells (BPX-603) in Subjects With HER2-Positive Solid Tumors
Bellicum Pharmaceuticals
NCT04893551 TERMINATED A Study of Tilvestamab (BGB149) in Relapsed, Platinum-resistant, High-grade Serous Ovarian Cancer (HGSOC) Participants
BerGenBio ASA
NCT01191775 COMPLETED A Study of PNT2258 in Patients With Advanced Solid Tumors
Sierra Oncology LLC - a GSK company
NCT03507699 COMPLETED Combined Immunotherapy and Radiosurgery for Metastatic Colorectal Cancer
Sheba Medical Center
NCT03730142 COMPLETED A Study of WXFL10030390 in Patients With Advanced Solid Tumors or Lymphoma
Shanghai Jiatan Pharmatech Co., Ltd
NCT04135261 COMPLETED A Study Evaluating the Safety, Tolerance and Anti-tumor Activity of a Study Drug in Subjects With Advanced Solid Tumors
Harbour BioMed US, Inc.
NCT02942095 COMPLETED Study of Ixazomib and Erlotinib in Solid Tumors
M.D. Anderson Cancer Center
NCT02094625 COMPLETED NAC to Prevent Cisplatin-induced Hearing Loss
Children's Hospital Los Angeles
NCT04084951 COMPLETED Study of SQZ-PBMC-HPV in Patients With HPV16+ Recurrent, Locally Advanced or Metastatic Solid Tumors
SQZ Biotechnologies
NCT03758781 COMPLETED IRX-2 Regimen Combined With Nivolumab in Recurrent/Metastatic Solid Tumors
H. Lee Moffitt Cancer Center and Research Institute
NCT03713905 COMPLETED Study of Recombinant Human Anti-PD-1 Monoclonal Antibody for Patients With Advanced Solid Tumors
Guangzhou Gloria Biosciences Co., Ltd.
NCT03396211 COMPLETED A Study to Evaluate Apatinib (Also Known as Rivoceranib) Plus Nivolumab in Participants With Unresectable or Metastatic Cancer
Elevar Therapeutics
NCT02737787 COMPLETED A Phase I Study of WT1 or NY-ESO-1 Vaccine and Nivolumab For Recurrent Ovarian Cancer
Memorial Sloan Kettering Cancer Center
NCT04112498 COMPLETED A Phase 1, Bioavailability Study of Relatlimab in Combination With Nivolumab
Bristol-Myers Squibb
NCT02890368 TERMINATED Trial of Intratumoral Injections of TTI-621 in Subjects With Relapsed and Refractory Solid Tumors and Mycosis Fungoides
Pfizer
NCT04089449 COMPLETED A Study of PRT811 in Participants With Advanced Solid Tumors, CNS Lymphoma and Gliomas
Prelude Therapeutics
NCT04381325 TERMINATED A Study of MSB0254 Injection in Advanced Solid Tumors
Suzhou Transcenta Therapeutics Co., Ltd.
NCT01332279 WITHDRAWN Everolimus, Erlotinib Hydrochloride, and Radiation Therapy in Treating Patients With Recurrent Head and Neck Cancer Previously Treated With Radiation Therapy
Fox Chase Cancer Center
NCT04630769 COMPLETED FT516 and IL2 With Enoblituzumab for Ovarian Cancer
Masonic Cancer Center, University of Minnesota
NCT03849469 COMPLETED A Study of XmAb®22841 Monotherapy & in Combination w/ Pembrolizumab in Subjects w/ Selected Advanced Solid Tumors
Xencor, Inc.
NCT04746612 TERMINATED First in Human Study to Evaluate the Safety, Tolerability of HH30134 in Advanced Solid Tumors
Haihe Biopharma Co., Ltd.
NCT03426254 WITHDRAWN Comparison of Safety and Clinical Benefit of Injections Subcutaneously Talazoparib Versus Oral Talazoparib in Patients With Solid Tumors
Center Trials & Treatment
NCT01570296 COMPLETED A Trial of Gefitinib in Combination With BKM120 in Patients With Advanced Non-Small Cell Lung Cancer, With Enrichment for Patients Whose Tumours Harbour Molecular Alterations of PI3K Pathway and Known to Overexpress EGFR
National Cancer Centre, Singapore
NCT01393509 COMPLETED The First-in-human Phase I Trial of PU-H71 in Patients With Advanced Malignancies
Memorial Sloan Kettering Cancer Center
NCT03886831 COMPLETED A Study of PRT543 in Participants With Advanced Solid Tumors and Hematologic Malignancies
Prelude Therapeutics
NCT03775850 COMPLETED A Study of EDP1503 in Patients With Colorectal Cancer, Breast Cancer, and Checkpoint Inhibitor Relapsed Tumors
Evelo Biosciences, Inc.
NCT04991740 COMPLETED A Study of JNJ-78306358 in Participants With Advanced Stage Solid Tumors
Janssen Research & Development, LLC
NCT04042480 TERMINATED A Study of SGN-CD228A in Advanced Solid Tumors
Seagen Inc.
NCT05388279 TERMINATED A Clinical Study to Evaluate the Safety and Tolerability of JS012 in Advanced or Metastatic Solid Tumors
Shanghai Junshi Bioscience Co., Ltd.
NCT05264038 COMPLETED A First in Human Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics Effects of OC514
Oncocross Australia Pty Ltd.
NCT05187858 COMPLETED A Study of LNP3794 in Subjects With NRAS/KRAS Mutated Advanced or Metastatic Refractory Solid Tumors
Lupin Ltd.
NCT02278250 COMPLETED First in Human Study of M4344 in Participants With Advanced Solid Tumors
EMD Serono Research & Development Institute, Inc.
NCT04060511 COMPLETED A Study of HS-10342 in Patients With Advanced Solid Tumor
Jiangsu Hansoh Pharmaceutical Co., Ltd.
NCT01969643 COMPLETED A Safety Study of SGN-LIV1A in Breast Cancer Patients
Seagen Inc.
NCT02219711 COMPLETED Phase 1/1b Study of MGCD516 in Patients With Advanced Cancer
Mirati Therapeutics Inc.
NCT02452268 TERMINATED A Phase I/Ib Study of NIZ985 in Combination With PDR001 in Adults With Metastatic Cancers
Novartis Pharmaceuticals
NCT04911894 COMPLETED A Study of Dose Escalation of IBI321 in Patients With Advanced Solid Tumors
Innovent Biologics (Suzhou) Co. Ltd.
NCT05531708 WITHDRAWN Exploratory Study of Novel MSLN CAR-T Cell Therapy in Patients With MSLN-positive Advanced Refractory Solid Tumors
Shanghai Pudong Hospital
NCT04911881 COMPLETED A Study of the Safety and Tolerability of IBI321 in Patients With Advanced Solid Tumors
Innovent Biologics (Suzhou) Co. Ltd.
NCT02721589 COMPLETED A Study to Evaluate the Safety and Tolerability of Using the SHR-1210 by Advanced Solid Tumor Subjects
Jiangsu HengRui Medicine Co., Ltd.
NCT03689192 COMPLETED Arginase-1 Peptide Vaccine in Patients With Metastatic Solid Tumors
Herlev Hospital
NCT03545971 COMPLETED A Study of IBI310 for the Treatment of Patients With Advanced Solid Tumors.
Innovent Biologics (Suzhou) Co. Ltd.
NCT02742935 COMPLETED A Study to Evaluate the Safety and Tolerability of Using SHR-1210 by Advanced Solid Tumor Subjects
Jiangsu HengRui Medicine Co., Ltd.
NCT04557384 TERMINATED A Study of Ramucirumab (LY3009806) Given by Injection Under the Skin in Participants With Advanced Cancer
Eli Lilly and Company
NCT04196283 COMPLETED A Study to Determine the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ABBV-368 Plus Tilsotolimod and Other Therapy Combinations in Participants With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma
AbbVie
NCT04547205 COMPLETED A Study of Anti-VEGFR2 AK109 in Subjects With Advanced Solid Tumors
Akeso
NCT03758001 COMPLETED First in Human Study of IBI101 in Chinese Subjects With Advanced Solid Tumors
Innovent Biologics (Suzhou) Co. Ltd.
NCT03589651 COMPLETED INCMGA00012 in Combination With Other Therapies in Patients With Advanced Solid Tumors
Incyte Corporation
NCT04324814 COMPLETED A Trial of SHR-1701 in Subjects With Advanced Solid Tumors
Atridia Pty Ltd.
NCT03889275 COMPLETED A Study of MEDI5395 in Combination With Durvalumab in Participants With Select Advanced Solid Tumors
MedImmune LLC
NCT03901950 COMPLETED Phase 1 Study to Evaluate the Safety, Tolerability and Pharmacokinetic Profile of XNW7201 in Subjects With Advanced Solid Tumors
Evopoint Biosciences Inc.
NCT03431948 COMPLETED Stereotactic Body Radiotherapy (SBRT) Plus Immunotherapy for Cancer
University of Chicago
NCT04626843 COMPLETED Intermittent Fasting and CLL/SLL
Eleah Stringer
NCT04542291 COMPLETED Targeting Pancreatic Cancer With Sodium Glucose Transporter 2 (SGLT2) Inhibition
Washington University School of Medicine
NCT04683354 COMPLETED Study of HL-085 in Patients With Advanced Solid Tumor Tumors
Kechow Pharma, Inc.
NCT05347979 COMPLETED Effect of Relacorilant on the Pharmacokinetics of the Sensitive P-glycoprotein Substrate Dabigatran Etexilate in Healthy Participants
Corcept Therapeutics
NCT03370302 TERMINATED A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics (PK) of TAK-228 as Single Agent in Adult East Asian Participants With Advanced Nonhematological Malignancies
Calithera Biosciences, Inc
NCT02000934 COMPLETED A Study of TAK-659 in Adult Participants With Advanced Solid Tumor and Lymphoma Malignancies
Calithera Biosciences, Inc
NCT03359733 WITHDRAWN A Study to Evaluate the Effect of Food on the Pharmacokinetics (PK) of TAK-659 in Participants With Advanced Solid Tumor
Calithera Biosciences, Inc
NCT02834247 TERMINATED A Study of TAK-659 in Combination With Nivolumab in Participants With Advanced Solid Tumors
Calithera Biosciences, Inc
NCT03338881 WITHDRAWN A Study to Assess Mass Balance, Pharmacokinetics (PK), and Metabolism of Orally Administered [14 C]-TAK-659 in Participants With Advanced Solid Tumor and/or Lymphoma Malignancies
Calithera Biosciences, Inc
NCT00658671 COMPLETED A Dose-Escalation Study of ENMD-2076 Administered Orally to Patients With Advanced Cancer
CASI Pharmaceuticals, Inc.
NCT05230290 COMPLETED Clinical Study of KD6001 in Advanced Solid Tumours
Shanghai Kanda Biotechnology Co., Ltd.
NCT02959905 COMPLETED Treatment of Advanced Solid Tumors With TSA-CTL(Tumor Specific Antigen-Induced Cytotoxic T Lymphocytes)
BGI, China
NCT01379287 COMPLETED Dose-Escalation Safety and Pharmacokinetic Study of Iso-Fludelone in Patients With Advanced Solid Tumors
Memorial Sloan Kettering Cancer Center
NCT04835714 TERMINATED A Study to Find a Safe and Effective Dose of BI 1701963 Alone and in Combination With BI 3011441 in Patients With Advanced Cancer and a Certain Mutation (Kirsten Rat Sarcoma Viral Oncogene Homologue [KRAS])
Boehringer Ingelheim
NCT04252339 COMPLETED RLY-1971 in Subjects With Advanced or Metastatic Solid Tumors
Hoffmann-La Roche
NCT05381935 WITHDRAWN A Study of ES014 (Anti-CD39/TGF-β Bispecific Antibody) in Patients With Locally Advanced or Metastatic Solid Tumors
Elpiscience Biopharma, Ltd.
NCT04202705 COMPLETED A First-in-human Dose-escalation and Expansion Study With the Antibody-drug Conjugate SYD1875
Byondis B.V.
NCT03420742 COMPLETED A Phase 1 Drug-Drug Interaction Study Between Brigatinib and the CYP3A Substrate, Midazolam, in Participants With ALK-Positive or ROS1-Positive Solid Tumors
Takeda
NCT05060276 WITHDRAWN Study to Assess an Anti-Trop2 Antibody Drug Conjugate in Relapsed or Refractory Solid Tumors
Sorrento Therapeutics, Inc.
NCT03786484 COMPLETED Study of PBF-999 in Solid Tumour Advanced Cancer
Palobiofarma SL
NCT01607905 COMPLETED Safety Study of KPT-330 (Selinexor) in Patients With Advanced or Metastatic Solid Tumor Cancer
Karyopharm Therapeutics Inc
NCT02197572 COMPLETED Effect of Sapanisertib (MLN0128) on the QTc Interval in Participants With Advanced Solid Tumors
Calithera Biosciences, Inc
NCT02032810 COMPLETED Phase I of Histone Deacetylase (HDAC) Inhibitor Panobinostat With Ipilimumab With Unresectable III/IV Melanoma
H. Lee Moffitt Cancer Center and Research Institute
NCT01444404 COMPLETED A Study of AMG 820 in Subjects With Advanced Solid Tumors
AmMax Bio, Inc.
NCT04430842 COMPLETED Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S
Quadriga Biosciences, Inc.
NCT04797468 WITHDRAWN A Phase 1 Study of the CD73 Inhibitor(HLX23) Alone in Participants With Solid Tumor
Shanghai Henlius Biotech
NCT04839367 COMPLETED Positron Emission Tomography (PET) Imaging of Participants With Confirmed Prostate Cancer Using 64Cu-SAR-bisPSMA (PROPELLER)
Clarity Pharmaceuticals Ltd
NCT01528046 COMPLETED Metformin in Children With Relapsed or Refractory Solid Tumors
H. Lee Moffitt Cancer Center and Research Institute
NCT02825940 COMPLETED A Study to Assess the Pharmacokinetics, Efficacy, and Safety of Atezolizumab Administered Intravenously (IV) as a Single Agent or in Combination With Chemotherapy in Chinese Participants With Locally Advanced or Metastatic Solid Tumors
Hoffmann-La Roche
NCT02998736 COMPLETED Trial of Perioperative Tadalafil and Influenza Vaccination in Cancer Patients Undergoing Major Surgical Resection of a Primary Abdominal Malignancy
Ottawa Hospital Research Institute
NCT05472220 WITHDRAWN Alpelisib in Combination With Carboplatin in Patients With Solid Tumors and HPV-Positive Squamous Cell Carcinoma
Pamela Munster
NCT04316169 WITHDRAWN Hydroxychloroquine, Abemaciclib and Endocrine Therapy in Hormone Receptor Positive (HR+)/Her 2 Negative Breast Cancer
Medical College of Wisconsin
NCT04049903 COMPLETED Study to Investigate the Safety, Blood Levels and Activity of MP0310 in Patients With Advanced Solid Tumors
Molecular Partners AG
NCT02607813 TERMINATED Phase I Study of LXH254 in Patients With Advanced Solid Tumors Haboring MAPK Pathway Alterations
Novartis Pharmaceuticals
NCT04659096 COMPLETED A Study of ION537 in Patients With Molecularly Selected Advanced Solid Tumors
Ionis Pharmaceuticals, Inc.
NCT03906643 WITHDRAWN HS-201, an HSP90 Inhibitor-linked Verteporfin for Detection of Solid Malignancies
Herbert Lyerly
NCT04699929 COMPLETED A Study to Evaluate YH001 in Subjects With Advanced Solid Tumors
Eucure (Beijing) Biopharma Co., Ltd
NCT04097769 COMPLETED The Safety, Tolerability, and Initial Efficacy of HX009 in Patients With Advanced Malignancies
Waterstone Hanxbio Pty Ltd
NCT04678921 COMPLETED Study of TJ210001 Administered in Subjects With Relapsed or Refractory Advanced Solid Tumors
I-Mab Biopharma US Limited
NCT04080024 COMPLETED A First-in-human Clinical Evaluation of SN132D in Patients With Breast and Pancreatic Cancer
Spago Nanomedical AB
NCT03082209 COMPLETED A Study of the Safety and Tolerability of ABBV-621 in Participants With Previously-Treated Solid Tumors and Hematologic Malignancies
AbbVie
NCT03051477 COMPLETED Trial of Mistletoe Extract in Patients With Advanced Solid Tumors
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT04672980 TERMINATED RTX-321 Monotherapy in Patients With HPV 16+ Tumors
Rubius Therapeutics
NCT03815682 TERMINATED RPTR-147 in Patients With Selected Solid Tumors and Lymphomas
Repertoire Immune Medicines
NCT05132803 WITHDRAWN TA-CIN Vaccine With Anti-PD-1 Therapy in Recurrent HPV16-associated Cancers
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT03517488 COMPLETED A Study of XmAb®20717 in Subjects With Selected Advanced Solid Tumors
Xencor, Inc.
NCT05528120 COMPLETED Food Effect Study on the Pharmacokinetics of VC004 Capsules in Healthy Adult Subjects
Jiangsu vcare pharmaceutical technology co., LTD
NCT03809767 COMPLETED A Study of CS1003 in Subjects With Advanced Solid Tumors or Lymphomas
CStone Pharmaceuticals
NCT04336124 COMPLETED Safety and Pharmacokinetic Study of CVM-1118 Extended-Release in Advanced Cancer Patients
TaiRx, Inc.
NCT03386942 COMPLETED A Study of MORAb-202 (Herein Referred to as Farletuzumab Ecteribulin) in Participants With Solid Tumors
Eisai Inc.
NCT01015222 COMPLETED Dasatinib, Bevacizumab, Paclitaxel in Patients With Advanced Malignancies
M.D. Anderson Cancer Center
NCT02627274 COMPLETED A Study Evaluating Safety, Pharmacokinetics, and Therapeutic Activity of RO6874281 as a Single Agent (Part A) or in Combination With Trastuzumab or Cetuximab (Part B or C)
Hoffmann-La Roche
NCT02857270 COMPLETED A Study of LY3214996 Administered Alone or in Combination With Other Agents in Participants With Advanced/Metastatic Cancer
Eli Lilly and Company
NCT03934359 COMPLETED A Study to Evaluate the Safety, Tolerability of DN1508052-01 in Advanced Solid Tumors
Shanghai De Novo Pharmatech Co., Ltd.
NCT03349073 COMPLETED An Extension Study for T-1101 (Tosylate) to Treat Advanced Refractory Solid Tumors
Taivex Therapeutics Corporation
NCT03195764 TERMINATED Safety and Tolerability Study for T-1101 (Tosylate) to Treat Advanced Refractory Solid Tumors
Taivex Therapeutics Corporation
NCT04434326 COMPLETED The Absorption, Metabolism and Excretion of [14C]CM082 in Human
AnewPharma
NCT02437916 TERMINATED Safety Study of AMG 228 to Treat Solid Tumors
Amgen
NCT00807859 COMPLETED Safety Study of AMG 386 to Treat HER2-positive Locally Recurrent or Metastatic Breast Cancer
Amgen
NCT04322552 COMPLETED A Pharmacokinetic Interaction Study Between Apatinib Mesylate and Transporter Pgp Substrate Digoxin in Advanced Solid Tumor Subjects
Jiangsu HengRui Medicine Co., Ltd.
NCT03926013 COMPLETED A Study of JNJ-63898081 in Participants With Advanced Stage Solid Tumors
Janssen Research & Development, LLC
NCT01253707 COMPLETED A Study of AMG 337 in Subjects With Advanced Solid Tumors
Amgen
NCT03371004 COMPLETED DM-CHOC-PEN Plus Radiation for Brain Tumors
DEKK-TEC, Inc.
NCT00890617 COMPLETED Cryotherapy in Treating Patients With Primary Stage I Non-Small Cell Lung Cancer or Lung Metastasis
Barbara Ann Karmanos Cancer Institute
NCT00784108 COMPLETED Optimizing Photodynamic Therapy of Cutaneous Neoplastic Diseases Via Structured Illumination and Real-time Dosimetry.
University of California, Irvine
NCT01220999 COMPLETED A Phase I Imaging and Pharmacodynamic Trial of CS-1008 in Patients With Metastatic Colorectal Cancer
Ludwig Institute for Cancer Research
NCT03856541 COMPLETED A Study of SHR-A1403 in Patients With Advanced Solid Tumor
Jiangsu HengRui Medicine Co., Ltd.
NCT04457180 COMPLETED A Pharmacokinetic Interaction Study Between Apatinib Mesylate and Repaglinide or Bupropion in Advanced Solid Tumor Subjects
Jiangsu HengRui Medicine Co., Ltd.
NCT04735796 TERMINATED Study of LM-102 in Subjects in Advanced Tumors
LaNova Medicines Limited
NCT02437370 COMPLETED Pembrolizumab and Docetaxel or Gemcitabine Hydrochloride in Treating Patients Urothelial Cancer
University of California, Davis
NCT01977638 COMPLETED Phase 1 Trial of CXD101 in Patients With Advanced Cancer
Oxford University Hospitals NHS Trust
NCT00794781 COMPLETED A Phase 1, Multicenter, Open-Label, Dose-Escalation, Safety, Pharmacokinetic, and Pharmacodynamic Study of E6201 in Subjects With Advanced Solid Tumors
Eisai Inc.
NCT02937116 COMPLETED First in Human Study of IBI308 in Chinese Subjects With Advanced Solid Tumors
Innovent Biologics (Suzhou) Co. Ltd.
NCT02252211 COMPLETED Safety and Bioimaging Trial of DS-8895a in Patients With Advanced EphA2 Positive Cancers
Ludwig Institute for Cancer Research
NCT00616941 COMPLETED Phase 1 Study of NY-ESO-1 Overlapping Peptides in Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Ludwig Institute for Cancer Research
NCT00972309 COMPLETED A Pilot Study of Vaccination With Epitope-Enhanced TARP Peptide and TARP Peptide-Pulsed Dendritic Cells in the Treatment of Stage D0 Prostate Cancer
National Cancer Institute (NCI)
NCT02829099 COMPLETED A Study of Safety, Pharmacokinetics and Pharmacodynamics of JNJ-64457107 in Participants With Advanced Stage Tumors
Janssen Research & Development, LLC
NCT04049617 TERMINATED Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Efficacy of Evixapodlin (Formerly GS-4224) in Participants With Advanced Solid Tumors
Gilead Sciences
NCT03883919 COMPLETED Liposomal Irinotecan Plus 5-FU / LV Combined With Paricalcitol in Patients With Advanced Pancreatic Cancer Progressed on Gemcitabine-based Therapy
Washington University School of Medicine
NCT04861948 TERMINATED IBI188 Combination Therapy in Solid Tumors
Innovent Biologics (Suzhou) Co. Ltd.
NCT05469490 WITHDRAWN Safety of Navoximod and NLG802 With Stereotactic Body Radiotherapy (SBRT) Treatment of Advanced Solid Tumors
Luke, Jason, MD
NCT03172819 COMPLETED Special Combination of OBP-301 and Pembrolizumab
Toshihiko Doi
NCT01407562 TERMINATED Study of Pazopanib, Paclitaxel, and Carboplatin in Patients With Advanced Solid Tumors
Rutgers, The State University of New Jersey
NCT03335540 COMPLETED An Adaptive Study to Match Patients With Solid Tumors to Various Immunotherapy Combinations Based Upon a Broad Biomarker Assessment
Bristol-Myers Squibb
NCT02049593 COMPLETED PARP Inhibitor BMN-673 and Temozolomide or Irinotecan Hydrochloride in Treating Patients With Locally Advanced or Metastatic Solid Tumors
Jonsson Comprehensive Cancer Center
NCT02943733 TERMINATED Safety of TAS-102 in Combination With Temozolomide for Metastatic Pancreatic NETs
University of Wisconsin, Madison
NCT03129776 TERMINATED Hyperpolarized 13C MR Imaging of Lactate in Patients With Locally Advanced Cervical Cancer (LACC) Cervical Cancer
Sunnybrook Health Sciences Centre
NCT03616574 COMPLETED First-in-human Study of CA102N Monotherapy and CA102N Combined With Trifluridine/Tipiracil (LONSURF) in Subjects With Advanced Solid Tumors
Holy Stone Healthcare Co., Ltd
NCT05262842 WITHDRAWN JS001+IMP4297 in Patients With Advanced Cancer
Shanghai Junshi Bioscience Co., Ltd.
NCT03894540 TERMINATED Dose Escalation and Dose Expansion Study of IPN60090 in Patients With Advanced Solid Tumours
Ipsen
NCT00981162 COMPLETED Sorafenib Tosylate and Everolimus in Treating Patients With Advanced Solid Tumors and Metastatic Pancreatic Cancer That Does Not Respond to Gemcitabine Hydrochloride
Roswell Park Cancer Institute
NCT01730118 COMPLETED Ad/HER2/Neu Dendritic Cell Cancer Vaccine Testing
National Cancer Institute (NCI)
NCT05440006 COMPLETED A Study of Food Effect on the Pharmacokinetics of Fuzuloparib Capsules in Chinese Healthy Adult Subjects
Jiangsu HengRui Medicine Co., Ltd.
NCT04272203 TERMINATED A Study to Determine Safety, Tolerability, Pharmacokinetics, and Recommended Phase 2 Dose (RP2D) of Intravenous ABBV-184 in Adult Participants With Previously Treated Cancers
AbbVie
NCT03056833 COMPLETED Ribociclib (Ribociclib (LEE-011)) With Platinum-based Chemotherapy in Recurrent Platinum Sensitive Ovarian Cancer
Ronald Buckanovich
NCT05008913 TERMINATED Human Absorption, Distribution, Metabolism, and Excretion Study of [14C]Adavosertib
AstraZeneca
NCT04554667 COMPLETED Heavy Lifting Strength Training in Head and Neck Cancer Survivors
University of Alberta
NCT04878484 WITHDRAWN Evaluate TCRT-ESO-A2 Autologous T Cells Expressing TCR Specific for NY-ESO-1 in Subjects With Advanced Solid Tumors
Athenex, Inc.
NCT01113476 COMPLETED Nab-paclitaxel, Gemcitabine, and Bevacizumab in Advanced Malignancies
M.D. Anderson Cancer Center
NCT03182673 TERMINATED The Study of SHR7390 in Combination With SHR-1210 and SHR3162 in Patients With Advanced Solid Tumors
Jiangsu HengRui Medicine Co., Ltd.
NCT02706392 TERMINATED Genetically Modified T-Cell Therapy in Treating Patients With Advanced ROR1+ Malignancies
Fred Hutchinson Cancer Center
NCT00819221 TERMINATED AZD2281 in Combination With Liposomal Doxorubicin in Advanced Solid Tumours
AstraZeneca
NCT05520372 COMPLETED Autologous Immune Enhancement Therapy (AIET) for Cancer Patients
Vinmec Research Institute of Stem Cell and Gene Technology
NCT01642342 TERMINATED Recombinant Albumin Fusion Protein sEphB4-HSA in Treating Patients With Metastatic or Recurrent Solid Tumors
University of Southern California
NCT01014936 COMPLETED First-in-Man, Dose-escalation Trial of C-met Kinase Inhibitor MSC2156119J in Subjects With Advanced Solid Tumors
EMD Serono
NCT02862457 COMPLETED Study of Epacadostat (INCB024360) Alone and In Combination With Pembrolizumab (MK-3475) With Chemotherapy and Pembrolizumab Without Chemotherapy in Participants With Advanced Solid Tumors (MK-3475-434)
Merck Sharp & Dohme LLC
NCT03782467 COMPLETED Phase 1 Study in Patients With Advanced and/or Refractory Solid Malignancies to Evaluate the Safety of ATOR-1015
Alligator Bioscience AB
NCT03970382 SUSPENDED A Study of Gene Edited Autologous Neoantigen Targeted TCR T Cells With or Without Anti-PD-1 in Patients With Solid Tumors
PACT Pharma, Inc.
NCT03088527 COMPLETED Phase 1, First-in-Human Study of RAD140 in Postmenopausal Women With Breast Cancer
Stemline Therapeutics, Inc.
NCT02278965 COMPLETED Metformin and Omega-3 Fatty Acids in Woman With a History of Early Stage Breast Cancer
Katherine D. Crew
NCT01573780 TERMINATED Gemcitabine Hydrochloride and Smac Mimetic TL32711 in Treating Patients With Advanced Solid Tumors
Roswell Park Cancer Institute
NCT04261075 COMPLETED IPH5201 as Monotherapy or in Combination With Durvalumab +/- Oleclumab in Subjects With Advanced Solid Tumors.
MedImmune LLC
NCT01862718 TERMINATED Fusion Guided Thermal Ablation Combined With External Beam Radiation for Hepatic Neoplasms
National Institutes of Health Clinical Center (CC)
NCT04324372 COMPLETED Clinical Study of HEC68498 in Patients With Advanced Refractory Solid Tumors
Sunshine Lake Pharma Co., Ltd.
NCT04852419 COMPLETED A PHASE 1B STUDY OF ZN-C5 IN CHINESE SUBJECTS
Zentera Therapeutics HK Limited
NCT01525069 TERMINATED Hepatic Arterial Infusion in Treating Patients With Locally Advanced, Non-Metastatic Cholangiocarcinoma
Washington University School of Medicine
NCT01061411 COMPLETED Dalteparin and Sunitinib Malate as First-Line Therapy in Treating Patients With Kidney Cancer That is Metastatic or Cannot Be Removed by Surgery
Roswell Park Cancer Institute
NCT01924260 COMPLETED Alisertib and Gemcitabine Hydrochloride in Treating Patients With Solid Tumors or Pancreatic Cancer
Edward Kim
NCT01673217 COMPLETED Decitabine, Vaccine Therapy, and Pegylated Liposomal Doxorubicin Hydrochloride in Treating Patients With Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Peritoneal Cancer
Roswell Park Cancer Institute
NCT04108676 COMPLETED Effect of Omeprazole on PK of Fluzoparib in Healthy Male Subjects
Jiangsu HengRui Medicine Co., Ltd.
NCT02926768 COMPLETED Phase I/II Study of CK-101 in NSCLC Patients and Other Advanced Solid Tumors
Checkpoint Therapeutics, Inc.
NCT04428086 COMPLETED A Pharmacokinetic Interaction Study Between Apatinib and Rosuvastatin or Metformin in Solid Tumor Subjects.
Jiangsu HengRui Medicine Co., Ltd.
NCT02719691 COMPLETED Phase I Study of MLN0128 and MLN8237 in Patients With Advanced Solid Tumors and Metastatic Triple-negative Breast Cancer
University of Colorado, Denver
NCT03297424 COMPLETED A Study of PLX2853 in Advanced Malignancies.
Opna Bio LLC
NCT02977195 COMPLETED First in Human Evaluation of Safety, Pharmacokinetics, and Clinical Activity of a Monoclonal Antibody Targeting Netrin 1 in Patients With Advanced/Metastatic Solid Tumors
Centre Leon Berard
NCT01527136 COMPLETED Entolimod in Treating Patients With Locally Advanced or Metastatic Solid Tumors That Cannot Be Removed By Surgery
Roswell Park Cancer Institute
NCT01540253 COMPLETED PI3K Inhibitor BKM120 and Docetaxel in Treating Patients With Advanced Solid Tumor That is Locally Advanced, Cannot Be Removed By Surgery, or Metastatic
Roswell Park Cancer Institute
NCT01497392 COMPLETED Dovitinib Lactate, Gemcitabine Hydrochloride, and Capecitabine in Treating Patients With Advanced or Metastatic Solid Tumors, Pancreatic Cancer and Biliary Cancers
Roswell Park Cancer Institute
NCT03208959 COMPLETED A Trial of HTI-1090 in Subjects With Advanced Solid Tumors
Atridia Pty Ltd.
NCT02759640 COMPLETED A Phase I Trial of HS-10241 in Solid Tumors
Atridia Pty Ltd.
NCT02071862 COMPLETED Study of the Glutaminase Inhibitor CB-839 in Solid Tumors
Calithera Biosciences, Inc
NCT03517956 COMPLETED Phase 1 Study of the Combination of Rogaratinib With Copanlisib in Patients With Fibroblast Growth Factor Receptor (FGFR)-Positive, Locally Advanced or Metastatic Solid Tumors
Bayer
NCT03133247 COMPLETED A Trial to Evaluate Safety and Tolerability of SHR-1316 in Cancer Patients
Atridia Pty Ltd.
NCT03080311 COMPLETED A Study of APG-1252 in Patients With SCLC or Other Solid Tumors
Ascentage Pharma Group Inc.
NCT02935907 COMPLETED APG-115 in Patients With Advanced Solid Tumors or Lymphomas
Ascentage Pharma Group Inc.
NCT03642834 COMPLETED Study of ICP-105 in Solid Tumors Patients
Beijing InnoCare Pharma Tech Co., Ltd.
NCT01468922 COMPLETED Pazopanib and ARQ 197 for Advanced Solid Tumors
National Cancer Institute (NCI)
NCT03502681 TERMINATED A Study Combining Eribulin Mesylate With Avelumab in Cisplatin Ineligible Metastatic Urothelial Cell Cancer Patients
Monika Joshi, MD
NCT03102320 COMPLETED Phase 1b Multi-indication Study of Anetumab Ravtansine in Mesothelin Expressing Advanced Solid Tumors
Bayer
NCT01984502 COMPLETED CyberKnife Accelerated Hemilarynx Stereotactic Radiotherapy Study for Early-stage Glottic Larynx Cancer
University of Texas Southwestern Medical Center
NCT02535325 COMPLETED Methoxyamine Hydrochloride, Pemetrexed Disodium, Cisplatin, and Radiation Therapy in Treating Patients With Stage IIIA-IV Non-small Cell Lung Cancer
National Cancer Institute (NCI)
NCT02602119 COMPLETED Intraoperative Imaging of Pulmonary Nodules by OTL38
University of Pennsylvania
NCT03852511 COMPLETED First in Human Study of NG-350A (an Oncolytic Adenoviral Vector Which Expresses an Anti-CD40 Antibody)
Akamis Bio
NCT02644291 COMPLETED Phase I Study of Mebendazole Therapy for Recurrent/Progressive Pediatric Brain Tumors
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT02508532 COMPLETED (NAVIGATOR) Study of BLU-285 in Patients With Gastrointestinal Stromal Tumors (GIST) and Other Relapsed and Refractory Solid Tumors
Blueprint Medicines Corporation
NCT02630199 COMPLETED Study of AZD6738, DNA Damage Repair/Novel Anti-cancer Agent, in Combination With Paclitaxel, in Refractory Cancer
Samsung Medical Center
NCT03023319 COMPLETED Bosutinib in Combination With Pemetrexed in Patients With Selected Metastatic Solid Tumors
Nagla Abdel Karim
NCT04335604 COMPLETED A Study of NOV140201 (JPI-547) in Subject With Advanced Solid Tumors
Onconic Therapeutics Inc.
NCT03588650 COMPLETED A Phase 1 Study of HLX20, a Human Monoclonal Antibody Targeting PD-L1Protein in Patients With Advanced Solid Tumors
Shanghai Henlius Biotech
NCT03596372 COMPLETED Study of BAY1834942 in Patients With Solid Tumors
Bayer
NCT03270176 COMPLETED A Dose-Finding Study of the Second Mitochondrial Activator of Caspases (SMAC) Mimetic Debio 1143 When Given in Combination With Avelumab to Participants With Advanced Solid Malignancies and to Participants With Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) After Platinum-Based Therapy
Debiopharm International SA
NCT02833753 COMPLETED Trial of Intraperitoneal (IP) Oxaliplatin in Combination With Intravenous FOLFIRI
University of Massachusetts, Worcester
NCT05010096 WITHDRAWN BAY1895344 and Copanlisib for the Treatment of Molecularly Selected Patients With Advanced Solid Tumors
M.D. Anderson Cancer Center
NCT03312842 COMPLETED A Phase Ia/Ib Study of CS1001 in Subjects With Advanced Solid Tumors
CStone Pharmaceuticals
NCT03444753 TERMINATED An Investigational Immunotherapy Study of BMS-986299 Alone and in Combination With Nivolumab and Ipilimumab in Participants With Solid Cancers That Have Spread or Cannot be Removed
Bristol-Myers Squibb
NCT03666988 TERMINATED First Time in Humans (FTIH) Study of GSK3368715 in Participants With Solid Tumors and Diffuse Large B-cell Lymphoma (DLBCL)
GlaxoSmithKline
NCT03406949 COMPLETED MGD009/MGA012 Combination in Relapsed/Refractory Cancer
MacroGenics
NCT03525795 COMPLETED ORIOn-E: A Study Evaluating CPI-1205 in Patients With Advanced Solid Tumors
Constellation Pharmaceuticals
NCT02801097 TERMINATED RRx-001 in Combination With Irinotecan in Metastatic or Advanced Cancer (PAYLOAD)
EpicentRx, Inc.
NCT04653142 COMPLETED A Study to Test Different Doses of BI 765063 Alone and in Combination With BI 754091 in Japanese Patients With Different Types of Advanced Cancer (Solid Tumors)
Boehringer Ingelheim
NCT03053466 COMPLETED APL-501 Study for Select Advanced or Relapsed/Recurrent Solid Tumors
Apollomics (Australia) Pty. Ltd.
NCT04088786 COMPLETED Phase I Trial HIPEC With Nal-irinotecan
Stony Brook University
NCT03916094 COMPLETED Evaluate Safety, Tolerability and Pharmacokinetics of HLX22 in Patients With Advanced Solid Tumors Overexpressing HER2
Shanghai Henlius Biotech
NCT03851146 COMPLETED A Study of Anti-Lewis Y Chimeric Antigen Receptor-T Cells (LeY-CAR-T) in Patients With Solid Tumours
Peter MacCallum Cancer Centre, Australia
NCT03172936 TERMINATED Study of the Safety and Efficacy of MIW815 With PDR001 in Patients With Advanced/Metastatic Solid Tumors or Lymphomas
Novartis Pharmaceuticals
NCT04009460 TERMINATED A Study of ES101 (PD-L1x4-1BB Bispecific Antibody) in Patients With Advanced Solid Tumors
Elpiscience Biopharma, Ltd.
NCT03071757 COMPLETED A Study of the Safety, Tolerability and Pharmacokinetics of ABBV-368 as a Single Agent and Combination in Subjects With Locally Advanced or Metastatic Solid Tumors
AbbVie
NCT02897778 COMPLETED Cardiac Safety Study of Entinostat in Men and Women With Advanced Solid Tumors
Syndax Pharmaceuticals
NCT04233060 COMPLETED A Study of CS3005 in Advanced Solid Tumors
CStone Pharmaceuticals
NCT00813566 COMPLETED Multi-Tracer PET Assessment of Primary Brain Tumors
University of Utah
NCT02734433 COMPLETED Study of Pexidartinib in Asian Subjects With Advanced Solid Tumors
Daiichi Sankyo Co., Ltd.
NCT02315066 COMPLETED Study Of OX40 Agonist PF-04518600 Alone And In Combination With 4-1BB Agonist PF-05082566
Pfizer
NCT04480190 WITHDRAWN Neoadjuvant Therapy in Biliary Adenocarcinoma
Jordan Kharofa
NCT03000257 COMPLETED A Study of Budigalimab (ABBV-181) in Participants With Advanced Solid Tumors
AbbVie
NCT04035473 COMPLETED A Study to Determine the Bioequivalence of Oraxol in Cancer Patients Treated With Intravenous Paclitaxel
Athenex, Inc.
NCT03726294 COMPLETED A Safety and Pharmacokinetic Study of NBM-BMX Administered Orally to Patients With Advanced Cancer
NatureWise Biotech & Medicals Corporation
NCT02354898 COMPLETED A Study of BBI503 in Advanced Solid Tumors, or BBI503/ Sorafenib in Advanced Hepatocellular Carcinoma
Sumitomo Pharma Co., Ltd.
NCT03366428 COMPLETED Phase 1 Study to Evaluate the Effect of DS-8201a on the QT/QTc Interval and Pharmacokinetics in HER2-Expressing Breast Cancer
Daiichi Sankyo Co., Ltd.
NCT01791595 COMPLETED A Phase I Trial of AZD3965 in Patients With Advanced Cancer
Cancer Research UK
NCT01655225 COMPLETED A Study of LY3023414 in Participants With Advanced Cancer
Eli Lilly and Company
NCT02035358 COMPLETED Immunotherapy Study for Metastatic Renal Cell Cancer
NewLink Genetics Corporation
NCT03147768 COMPLETED Laser Tissue Welding - Distal Pancreatectomy Sealing Study
Laser Tissue Welding, Inc.
NCT03682744 WITHDRAWN CAR-T Intraperitoneal Infusions for CEA-Expressing Adenocarcinoma Peritoneal Metastases or Malignant Ascites (IPC)
Sorrento Therapeutics, Inc.
NCT02076620 COMPLETED L19TNFα in Combination With Doxorubicin in Patients With Advanced Solid Tumours
Philogen S.p.A.
NCT03924245 TERMINATED Olaparib and Entinostat in Patients With Recurrent, Platinum-Refractory, Resistant Ovarian, Primary Peritoneal, Fallopian Tube Cancers
Vanderbilt-Ingram Cancer Center
NCT02364492 COMPLETED A Phase I Study of a Therapeutic Vaccine Candidate in Patients With Localized Breast Cancer at High-Risk of Relapse
Institut Pasteur
NCT02324439 COMPLETED Flaxseed as Maintenance Therapy for Ovarian Cancer Patients in Remission
Southern Illinois University
NCT02410512 COMPLETED A Study to Assess the Safety and Pharmacokinetics of MOXR0916 and Atezolizumab (Also Known as MPDL3280A or Anti-PD-L1) in Participants With Locally Advanced or Metastatic Solid Tumors
Genentech, Inc.
NCT02646748 COMPLETED Pembrolizumab Combined With Itacitinib (INCB039110) and/or Pembrolizumab Combined With INCB050465 in Advanced Solid Tumors
Incyte Corporation
NCT01553071 TERMINATED Phase I Trial of IV Fenretinide (4-HPR) Plus IV Safingol for Patients With Relapsed Malignancies
South Plains Oncology Consortium
NCT03600090 COMPLETED Phase I Study of EOC202 Plus Paclitaxel in Chinese Patients With Metastatic Breast Cancer
Taizhou EOC Pharma Co., Ltd.
NCT03579628 COMPLETED AsiDNA (a DNA Repair Inhibitor) Administered IntraVenously in Advanced Solid Tumors
Valerio Therapeutics
NCT01904123 COMPLETED STAT3 Inhibitor WP1066 in Treating Patients With Recurrent Malignant Glioma or Progressive Metastatic Melanoma in the Brain
M.D. Anderson Cancer Center
NCT03458117 COMPLETED T-VEC in Non-melanoma Skin Cancer
University of Zurich
NCT03951116 COMPLETED Study of FCN-437c in Patients With Advanced Solid Tumors
Fochon Pharmaceuticals, Ltd.
NCT01790035 TERMINATED Probiotic LGG for Prevention of Side Effects in Patients Undergoing Chemoradiation for Gastrointestinal Cancer
Washington University School of Medicine
NCT00702494 COMPLETED Phase I Study on Monoclonal Antibody TB-403 Directed Against PlGF in Patients With Solid Tumours
BioInvent International AB
NCT03138538 TERMINATED M8891 First in Human in Solid Tumors
EMD Serono Research & Development Institute, Inc.
NCT02427581 WITHDRAWN Safety and Immunogenicity of a Personalized Synthetic Long Peptide Breast Cancer Vaccine Strategy in Patients With Persistent Triple-Negative Breast Cancer Following Neoadjuvant Chemotherapy
Washington University School of Medicine
NCT03203876 COMPLETED A Safety Study of Lirilumab in Combination With Nivolumab or in Combination With Nivolumab and Ipilimumab in Advanced and/or Metastatic Solid Tumors
Bristol-Myers Squibb
NCT02526017 COMPLETED Study of Cabiralizumab in Combination With Nivolumab in Patients With Selected Advanced Cancers
Five Prime Therapeutics, Inc.
NCT01226732 COMPLETED A Study of the Hsp90 Inhibitor AUY922 Plus Capecitabine for the Treatment of Patients With Advanced Solid Tumors
SCRI Development Innovations, LLC
NCT02442414 COMPLETED A Phase 1 Study of KBP-5209 in Patients With Advanced Solid Tumors
Sihuan Pharmaceutical Holdings Group Ltd.
NCT04156100 TERMINATED A Study in Subjects With Advanced Solid Tumors
Agenus Inc.
NCT03101488 COMPLETED Phase I Study of KN035 in Chinese Subjects With Advanced Solid Tumors
3D Medicines (Sichuan) Co., Ltd.
NCT03739138 TERMINATED Intratumoral/Intralesional Administration of MK-4621/JetPEI™ With or Without Pembrolizumab in Participants With Advanced/Metastatic or Recurrent Solid Tumors (MK-4621-002)
Merck Sharp & Dohme LLC
NCT01296581 COMPLETED Safety Study of X-82 in Patients With Advanced Solid Tumors
Tyrogenex
NCT03910530 COMPLETED A Study of INCMGA00012, INCB001158, and the Combination in Japanese Participants With Advanced Solid Tumors
Incyte Biosciences Japan GK
NCT03551782 COMPLETED A Study of Cetrelimab (JNJ-63723283), a Programmed Cell Death Receptor-1 (PD-1) Inhibitor, Administered in Combination With Apalutamide in Participants With Metastatic Castration-Resistant Prostate Cancer
Janssen Research & Development, LLC
NCT03953742 COMPLETED Study of CPI-200 in Patients With Advanced Tumors
Coordination Pharmaceuticals, Inc.
NCT02250157 COMPLETED A Dose-regimen Finding Study to Evaluate Safety, Tolerability, Pharmacokinetics and Activity of Oratecan in Subjects With Advanced Malignancies
Athenex, Inc.
NCT03475251 COMPLETED A Study of CS1003 in Subjects With Advanced Solid Tumors
CStone Pharmaceuticals
NCT02493751 COMPLETED A Study Of Avelumab In Combination With Axitinib In Advanced Renal Cell Cancer (JAVELIN Renal 100)
Pfizer
NCT05242926 WITHDRAWN Absorption and Excretion of Oral Docetaxel
Modra Pharmaceuticals
NCT03987685 COMPLETED Evaluate Oral Topotecan With HM30181A Monotherapy in Patients With Advanced Malignancies
Athenex, Inc.
NCT02596503 COMPLETED A Study of Eribulin in Combination With Oral Irinotecan for Adolescent and Young Adult Patients With Relapsed or Refractory Solid Tumors
University of Colorado, Denver
NCT02559024 TERMINATED Anti-OX40 Antibody (MEDI6469) in Patients With Metastatic Colorectal Cancer
Providence Health & Services
NCT02235688 COMPLETED Study to Investigate the Safety and Activity of Aldoxorubicin Plus Gemcitabine in Subjects With Metastatic Solid Tumors
ImmunityBio, Inc.
NCT01706835 COMPLETED Study to Investigate the Pharmacolkinetics of Aldoxorubicin (INNO-206;DOXO-EMCH) Administered as a 30 Minute Infusion Every 3 Weeks in Subjects With Advanced Solid Tumors
ImmunityBio, Inc.
NCT01673438 COMPLETED Phase 1b Study to Investigate the Safety and Maximum Tolerated Dose of Aldoxorubicin (INNO-206) Plus Doxorubicin HCL in Subjects With Advanced Solid Tumors
ImmunityBio, Inc.
NCT04522557 COMPLETED Type I Interferon Alfa-2a in Postmastectomy Breast Reconstruction
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
NCT02705963 COMPLETED A Drug-Drug Interaction Study to Assess the Effect of Trametinib on the Pharmacokinetics of an Oral Contraceptive in Female Patients With Solid Tumors
Novartis Pharmaceuticals
NCT03248843 COMPLETED A Study of PD-L1 Antibody KN035 in Japanese Subjects With Locally Advanced or Metastatic Solid Tumors
3D Medicines (Sichuan) Co., Ltd.
NCT02723864 COMPLETED Veliparib (ABT-888), an Oral PARP Inhibitor, and VX-970, an ATR Inhibitor, in Combination With Cisplatin in People With Refractory Solid Tumors
National Cancer Institute (NCI)
NCT04811898 COMPLETED A Dose Escalation Study of LNA-i-Mir-221 for Cancer Treatment
Azienda Ospedaliera Universitaria Mater Domini, Catanzaro
NCT02947165 COMPLETED Phase I/Ib Study of NIS793 in Combination With PDR001 in Patients With Advanced Malignancies.
Novartis Pharmaceuticals
NCT03665129 TERMINATED IPH5401 (Anti-C5aR) in Combination With Durvalumab in Patients With Advanced Solid Tumors
Innate Pharma
NCT02909452 COMPLETED Continuation Study of Entinostat in Combination With Pembrolizumab in Patients With Advanced Solid Tumors
Syndax Pharmaceuticals
NCT03015324 COMPLETED Biological Effects of Agent on PAR-4 Levels With Resected Solid Tumors
Peng Wang, MD PhD
NCT01362374 COMPLETED Safety and Clinical Pharmacology of GDC-0068 in Combination With Docetaxel, Fluoropyrimidine Plus Oxaliplatin, Paclitaxel, or Enzalutamide in Participants With Advanced Solid Tumors
Genentech, Inc.
NCT03168438 TERMINATED Letetresgene Autoleucel Engineered T Cells Alone and in Combination With Pembrolizumab in NY-ESO-1 Positive Multiple Myeloma
GlaxoSmithKline
NCT03084926 COMPLETED First-in-human Study to Investigate Safety, Blood Levels and Activity of MP0274 in Cancer Patients With HER2-positive Solid Tumors
Molecular Partners AG
NCT03823989 COMPLETED Intravenously Administered Liposomal PROMITIL in Combination With External Beam Radiotherapy in Cancer Patients
Lipomedix Pharmaceuticals Inc.
NCT01004861 COMPLETED Safety Study of PLX108-01 in Patients With Solid Tumors
Daiichi Sankyo
NCT01143779 COMPLETED FLT-PET as an Imaging Biomarker With Temsirolimus, Topotecan, and Bortezomib
M.D. Anderson Cancer Center
NCT04810208 TERMINATED Intratumoural Injection of a Novel NanoZolid®-Docetaxel Depot Formulation in Patients With Advanced Solid Tumours
Lidds AB
NCT02675439 TERMINATED Safety and Efficacy of MIW815 (ADU-S100) +/- Ipilimumab in Patients With Advanced/Metastatic Solid Tumors or Lymphomas
Chinook Therapeutics, Inc. (formerly Aduro)
NCT01441115 TERMINATED ECI301 and Radiation for Advanced or Metastatic Cancer
National Cancer Institute (NCI)
NCT04191928 COMPLETED Pharmacokinetics of Apixaban in Patients Undergoing Pancreaticoduodenectomy
Thomas Jefferson University
NCT00999401 COMPLETED A Study of Oral Sapacitabine and Oral Seliciclib in Patients With Advanced Solid Tumors
Cyclacel Pharmaceuticals, Inc.
NCT01772004 COMPLETED Avelumab in Metastatic or Locally Advanced Solid Tumors (JAVELIN Solid Tumor)
EMD Serono Research & Development Institute, Inc.
NCT02573259 COMPLETED A Dose Escalation Study Of PF-06801591 In Melanoma, Head And Neck Cancer (SCCHN), Ovarian, Sarcoma, Non-Small Cell Lung Cancer, Urothelial Carcinoma or Other Solid Tumors
Pfizer
NCT00687505 COMPLETED Safety Study of FP-1039 To Treat Cancer
Five Prime Therapeutics, Inc.
NCT03400306 WITHDRAWN A Study Evaluating the Bioavailability and Food Effect of Veliparib Tablets Followed by an Extension in Subjects With Ovarian Cancer
AbbVie
NCT03931681 COMPLETED A Study of OKI-179 in Patients With Solid Tumors
OnKure, Inc.
NCT02660034 COMPLETED The Safety, Pharmacokinetics and Antitumor Activity of BGB-A317 in Combination With BGB-290 in Participants With Advanced Solid Tumors
BeiGene
NCT00730639 COMPLETED A Phase 1 Study of Nivolumab (BMS-936558) in Subjects With Advanced or Recurrent Malignancies
Bristol-Myers Squibb
NCT03348514 COMPLETED Safety, Dose Tolerance, Pharmacokinetics, and Pharmacodynamics Study of CPX-POM in Patients With Advanced Solid Tumors
CicloMed LLC
NCT02189174 TERMINATED Study of CLR457 Administered Orally in Adult Patients With Advanced Solid Malignancies
Novartis Pharmaceuticals
NCT03673020 COMPLETED Phase 1a Study to Evaluate Immunogenicity of ASV®
Agenus Inc.
NCT02716948 COMPLETED SRS and Nivolumab in Treating Patients With Newly Diagnosed Melanoma Metastases in the Brain or Spine
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT04973020 COMPLETED A Drug-drug Interaction Study of SHR6390 on Healthy Chinese Volunteers
Jiangsu HengRui Medicine Co., Ltd.
NCT04328506 COMPLETED Bioequivalency Study of CM082 Tablet in Healthy Volunteers
AnewPharma
NCT02767921 TERMINATED sEphB4-HSA Before Surgery in Treating Patients With Bladder Cancer, Prostate Cancer, or Kidney Cancer
University of Southern California
NCT01324141 TERMINATED Topical MTS-01 for Dermatitis During Radiation and Chemotherapy for Anal Cancer
National Cancer Institute (NCI)
NCT03319459 COMPLETED FATE-NK100 as Monotherapy and in Combination With Monoclonal Antibody in Subjects With Advanced Solid Tumors
Fate Therapeutics
NCT02407990 COMPLETED Study of the Safety, Pharmacokinetics and Antitumor Activities of BGB-A317 in Participants With Advanced Tumors
BeiGene
NCT03364049 COMPLETED Study of MK-7162 in Combination With Pembrolizumab (MK-3475) in Adult Participants With Advanced Solid Tumors (MK-7162-002)
Merck Sharp & Dohme LLC
NCT01922752 COMPLETED To Determine the Maximum Tolerated Dose of Oral CEP-37440 in Patients With Advanced or Metastatic Solid Tumors
Teva Branded Pharmaceutical Products R&D, Inc.
NCT03497429 COMPLETED A Study of Niraparib as Single Agent in Participants With Advanced Solid Tumors
Takeda
NCT03661632 COMPLETED An Investigational Immunotherapy Study of BMS-986310 Administered Alone and in Combination With Nivolumab in Patients With Advanced Solid Tumors
Bristol-Myers Squibb
NCT02660281 COMPLETED URMC Related Haplo-identical Donor BMT
University of Rochester
NCT04508179 COMPLETED A Phase 1 SAD and MAD Study of the Safety, Tolerability and PK of 7HP349 in Normal Healthy Male Subjects
7 Hills Pharma, LLC
NCT02282371 COMPLETED Cetuximab + BYL719 + IMRT (Intensity-Modulated Radiation Therapy) in Stage III/IVB Head and Neck Squamous Cell Cancer (HNSCC)
Memorial Sloan Kettering Cancer Center
NCT03752177 TERMINATED A Study of LY3415244 in Participants With Advanced Solid Tumors
Eli Lilly and Company
NCT05086848 COMPLETED A Study of Irinotecan Hydrochloride Liposome in Combination With 5-FU/LV in Advanced Solid Tumors
Jiangsu HengRui Medicine Co., Ltd.
NCT05086822 COMPLETED A Study of Irinotecan Hydrochloride Liposome in Advanced Solid Tumors
Jiangsu HengRui Medicine Co., Ltd.
NCT00989651 COMPLETED Carboplatin, Paclitaxel, Bevacizumab, and Veliparib in Treating Patients With Newly Diagnosed Stage II-IV Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer
National Cancer Institute (NCI)
NCT02914470 COMPLETED Carboplatin-cyclophosphamide Combined With Atezolizumab
The Netherlands Cancer Institute
NCT05084456 WITHDRAWN Oral Docetaxel in Patients With Normal or Impaired Liver Function
Modra Pharmaceuticals
NCT04941040 COMPLETED Opioid Free VS Opioid Anesthesia for Craniotomies
Kasr El Aini Hospital
NCT03147378 COMPLETED Food Effect Study of ModraDoc006 in Combination With Ritonavir
Modra Pharmaceuticals
NCT04585724 WITHDRAWN Stereotactic Radiosurgery With Abemaciclib, Ribociclib, or Palbociclib in Treating Patients With Hormone Receptor Positive Breast Cancer With Brain Metastases
Emory University
NCT04418141 COMPLETED A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of CN1
Curon Biopharmaceutical (Australia) Co Pty Ltd
NCT01417546 COMPLETED NHS-IL12 for Solid Tumors
National Cancer Institute (NCI)
NCT03895684 COMPLETED Phase 1 Trial of the LSD1 Inhibitor SP-2577 (Seclidemstat) in Patients With Advanced Solid Tumors
Salarius Pharmaceuticals, LLC
NCT03489343 COMPLETED Sym023 (Anti-TIM-3) in Patients With Advanced Solid Tumor Malignancies or Lymphomas
Symphogen A/S
NCT01910597 COMPLETED Phase I, Dose-Escalation Study of Soluble Beta-Glucan (SBG) in Patients With Advanced Solid Tumors
Prince of Songkla University
NCT01586624 COMPLETED A Phase I Trial of Vandetanib (AZD6474) and Selumetinib (AZD6244) for Solid Tumours Including Non Small Cell Lung Cancer (VanSel-1)
Cancer Research UK
NCT02308722 COMPLETED SBRT Pre-operatively for Pancreatic Cancer
University of Oxford
NCT04252248 TERMINATED Decitabine Treatment in HPV-Induced Anogenital and Head and Neck Cancer Patients After Radiotherapy or as Novel Late Salvage
University Hospital Heidelberg
NCT03006029 COMPLETED Dose Escalation Study of TAB08 in Patients With Advanced Solid Neoplasms
Theramab LLC
NCT01288430 TERMINATED A Study of DS-2248 in Participants With Advanced Solid Tumors
Daiichi Sankyo
NCT03745807 COMPLETED An Investigational Study of NKTR-214 Combined With Nivolumab in Japanese Participants With Advanced Solid Tumors
Bristol-Myers Squibb
NCT03607955 WITHDRAWN Paclitaxel + Carboplatin With AVB-S6-500 in Women With Stage III or IV Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer Receiving Neoadjuvant Chemotherapy
Washington University School of Medicine
NCT03403725 TERMINATED MEN1309 I.v. Infusion in Pts With CD205-positive Metastatic Solid Tumors and Relapsed or Refractory NHL Ph I Study
Menarini Group
NCT03009292 COMPLETED Pharmacokinetic Study of E7080/Lenvatinib in Chinese Subjects With Solid Tumor
Eisai Co., Ltd.
NCT04158349 TERMINATED Intraperitoneal Oxaliplatin in Combo w IV mFOLFIRI for Peritoneal Carcinomatosis From Colorectal & Appendiceal Cancer
University of Utah
NCT03991494 COMPLETED Study to Investigate the Absorption, Metabolism, and Excretion of [14C]-Pamiparib in Participants With Advanced Cancer
BeiGene
NCT04071262 COMPLETED A Study of Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Therapies in Japanese Participants With Advanced Cancer
Eli Lilly and Company
NCT03051035 TERMINATED First-in-Human Study of KO-947 in Non-Hematological Malignancies
Kura Oncology, Inc.
NCT02111824 TERMINATED A Multimodality Image-guided System for Peripheral Lung Cancer Diagnosis and Therapy
The Methodist Hospital Research Institute
NCT02478866 COMPLETED Safety and Pharmacokinetics of BPI-9016M in Patients With Advanced Solid Tumors
Betta Pharmaceuticals Co., Ltd.
NCT04014257 COMPLETED A Phase 1 Study of NOV1601(CHC2014) in Adult Subjects With Solid Organ Malignancies
Handok Inc.
NCT02730481 COMPLETED A Study to Evaluate the Safety, Tolerability, MTD, PK, and Activity of Oraxol in Subjects w Adv. Malignancies
Athenex, Inc.
NCT04111445 TERMINATED Study of ADG116 in Patients With Advanced/Metastatic Solid Tumors
Adagene Inc
NCT02588612 COMPLETED Letetresgene Autoleucel Engineered T Cells in NY-ESO -1 Positive Advanced Non-Small Cell Lung Cancer (NSCLC)
GlaxoSmithKline
NCT02777710 COMPLETED Evaluation of Safety and Activity of an Anti-PDL1 Antibody (DURVALUMAB) Combined With CSF-1R TKI (PEXIDARTINIB) in Patients With Metastatic/Advanced Pancreatic or Colorectal Cancers
Centre Leon Berard
NCT01723020 COMPLETED A Phase 1 Study Evaluating AMG 232 in Advanced Solid Tumors or Multiple Myeloma
Kartos Therapeutics, Inc.
NCT03057145 COMPLETED Combination Study of Prexasertib and Olaparib in Patients With Advanced Solid Tumors
Geoffrey Shapiro, MD, PhD
NCT04099277 TERMINATED A Study of LY3435151 in Participants With Solid Tumors
Eli Lilly and Company
NCT02655822 COMPLETED Phase 1/1b Study to Evaluate the Safety and Tolerability of Ciforadenant Alone and in Combination With Atezolizumab in Advanced Cancers
Corvus Pharmaceuticals, Inc.
NCT03471286 TERMINATED A Window of Opportunity Study to Investigate Mechanisms of Actions of Novel Therapeutic Agents in Patients With Resectable Solid Tumor Malignancies
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT04771390 COMPLETED Study to Compare How the Body Absorbs, Distributes and Excretes the Drug Selitrectinib (BAY2731954) Given as Two Different Tablet Formulations or as Liquid Formulations Including the Effect of Food on the Absorption, Distribution or Excretion of the Different Formulations in Healthy Participants
Bayer
NCT04351165 COMPLETED BA Study of IMP4297 (20mg vs 10mg) in Healthy Male Subjects
Impact Therapeutics, Inc.
NCT04584515 COMPLETED IMP4297 DDI (Drug-Drug Interaction)Trial in Healthy Male Volunteers
Impact Therapeutics, Inc.
NCT04187456 COMPLETED A Study in Healthy Male Subjects to Understand How Savolitinib When Taken With Midazolam Behaves Inside the Body
AstraZeneca
NCT02564198 COMPLETED A Study of Ramucirumab (LY3009806) in Children With Refractory Solid Tumors
Eli Lilly and Company
NCT02058550 COMPLETED Phone or Email Reminder in Increasing Vaginal Dilator Use in Patients With Gynecologic Cancers Undergoing Brachytherapy
Stanford University
NCT02367196 COMPLETED A Phase 1, Dose Finding Study of CC-90002 in Subjects With Advanced Solid and Hematologic Cancers
Celgene
NCT02177682 TERMINATED Study of Afuresertib Monotherapy in Japanese Relapsed Multiple Myeloma Patients
Novartis Pharmaceuticals
NCT02227082 COMPLETED Olaparib and Radiotherapy in Inoperable Breast Cancer
The Netherlands Cancer Institute
NCT01826877 COMPLETED Autologous Dendritic Cells in Treating Patients With Metastatic Kidney Cancer
Jonsson Comprehensive Cancer Center
NCT01063816 COMPLETED A Study of ABT-888 in Combination With Carboplatin and Gemcitabine in Subjects With Advanced Solid Tumors
AbbVie (prior sponsor, Abbott)
NCT03636750 COMPLETED A Study of Injection HB002.1T in Subjects With Solid Tumor
Huabo Biopharm Co., Ltd.
NCT04312282 TERMINATED The Effect of Tesetaxel on the QTc Interval and the Effect of Food, Itraconazole, and Rifampin on Tesetaxel Pharmacokinetics in Patients With Advanced Solid Tumors
Odonate Therapeutics, Inc.
NCT01748825 COMPLETED AZD1775 for Advanced Solid Tumors
National Cancer Institute (NCI)
NCT04178902 TERMINATED A Study of the Safety and Tolerability of ABBV-467 in Adult Participants With Relapsed/Refractory (R/R) Multiple Myeloma
AbbVie
NCT04258527 COMPLETED Phase 1 Study of Pemigatinib in Patients With Advanced Malignancies With FGF/FGFR Alterations
Innovent Biologics (Suzhou) Co. Ltd.
NCT03967093 TERMINATED A Study of BXQ-350 in Children and Young Adults With Relapsed Solid Tumors
Bexion Pharmaceuticals, Inc.
NCT02859857 COMPLETED Phase 1 Study of BXQ-350 in Adult Patients With Advanced Solid Tumors
Bexion Pharmaceuticals, Inc.
NCT04427774 TERMINATED A Study of Surufatinib Plus Sintilimab in Patients With Advanced Solid Tumor
Innovent Biologics (Suzhou) Co. Ltd.
NCT02546531 COMPLETED Defactinib Combined With Pembrolizumab and Gemcitabine in Patients With Advanced Cancer
Washington University School of Medicine
NCT02510001 COMPLETED MEK and MET Inhibition in Colorectal Cancer
University of Oxford
NCT02908451 TERMINATED A Study of AbGn-107 in Patients With Gastric, Colorectal, Pancreatic or Biliary Cancer
AbGenomics B.V Taiwan Branch
NCT03360734 COMPLETED Combination of Gatipotuzumab and Tomuzotuximab in Patients With Solid Tumors
Glycotope GmbH
NCT02715531 COMPLETED A Study of the Safety and Efficacy of Atezolizumab Administered in Combination With Bevacizumab and/or Other Treatments in Participants With Solid Tumors
Hoffmann-La Roche
NCT02696642 COMPLETED Phase I Study of Anetumab Ravtansine in Hepatic or Renal Impairment
Bayer
NCT03292783 COMPLETED This is a Study to Evaluate the Safety and Tolerability of the Study Drug ABL001, and to Determine the Maximum Tolerated Dose and/or Recommended Phase 2 Study Dose of ABL001
ABL Bio, Inc.
NCT01343043 COMPLETED A Pilot Study of Genetically Engineered NY-ESO-1 Specific NY-ESO-1ᶜ²⁵⁹T in HLA-A2+ Patients With Synovial Sarcoma
GlaxoSmithKline
NCT03077607 COMPLETED A Study to Evaluate the Effect of Itraconazole and Rifampin on the Pharmacokinetics of Talazoparib in Patients With Advanced Solid Tumors
Pfizer
NCT02232243 COMPLETED HCQ on PAR-4 Levels in Patients With Resectable Solid Tumors
Peng Wang, MD PhD
NCT01848834 COMPLETED Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-012/KEYNOTE-012)
Merck Sharp & Dohme LLC
NCT01840579 COMPLETED Study of Pembrolizumab (MK-3475) Monotherapy in Advanced Solid Tumors and Pembrolizumab Combination Therapy in Advanced Non-small Cell Lung Cancer/ Extensive-disease Small Cell Lung Cancer (MK-3475-011/KEYNOTE-011)
Merck Sharp & Dohme LLC
NCT02168725 TERMINATED Dose-escalation, Safety and Pharmacokinetic Study of Briciclib in Advanced Solid Tumors
Traws Pharma, Inc.
NCT02096614 COMPLETED Investigator Initiated Phase 1 Study of TBI-1201
Mie University
NCT03332576 COMPLETED Phase 1b Study of a Cancer Vaccine to Treat Patients With Advanced Stage Ovarian, Fallopian or Peritoneal Cancer
ImmunoVaccine Technologies, Inc. (IMV Inc.)
NCT03804515 TERMINATED A Mass Balance and Pharmacokinetics Study of 14C-Labeled Poziotinib in Cancer Patients Suitable for Treatment With Poziotinib
Spectrum Pharmaceuticals, Inc
NCT01760525 COMPLETED A Phase I Dose Escalation Study of CGM097 in Adult Patients With Selected Advanced Solid Tumors
Novartis Pharmaceuticals
NCT02533674 COMPLETED Multicenter, Open-label, Clinical and Pharmacokinetic Study of PM060184 in Combination With Gemcitabine in Selected Patients With Advanced Solid Tumors
PharmaMar
NCT02292173 COMPLETED Trametinib in Combination With Sorafenib in Patients With Advanced Hepatocellular Cancer
H. Lee Moffitt Cancer Center and Research Institute
NCT02097810 COMPLETED Study of Oral RXDX-101 in Adult Patients With Locally Advanced or Metastatic Cancer Targeting NTRK1, NTRK2, NTRK3, ROS1, or ALK Molecular Alterations.
Hoffmann-La Roche
NCT02162888 COMPLETED A Phase I, Bioequivalence Study to Evaluate Two Formulations of Bendamustine (BDM) Hydrochloride (HCl) Administered to Cancer Patients
Eagle Pharmaceuticals, Inc.
NCT02609230 COMPLETED A Dose-Escalation Study of Onc201 Administered Every One or Three Weeks in Advanced Solid Tumors and Multiple Myeloma
Fox Chase Cancer Center
NCT02827968 COMPLETED Phase 1 Study of Anti-PD-L1 Monoclonal Antibody KN035 to Treat Locally Advanced or Metastatic Solid Tumors
3D Medicines (Sichuan) Co., Ltd.
NCT04515043 COMPLETED EXPLORATORY STUDY Addendum to INVAC1-CT-101 (NCT02301754)
Invectys
NCT03359850 COMPLETED Pharmacokinetic and Safety Study of Niraparib With Normal or Moderate Hepatic Impairment Patients
Tesaro, Inc.
NCT01222637 COMPLETED CetuGEX™: Phase 1 Study in Cancer Patients
Glycotope GmbH
NCT01222624 COMPLETED PankoMab-GEX™: Phase 1 Dose Escalation Study
Glycotope GmbH
NCT03006887 COMPLETED Phase 1b Trial of Lenvatinib Plus Pembrolizumab in Participants With Selected Solid Tumors
Eisai Co., Ltd.
NCT03481816 COMPLETED Treatment of Castration Resistant Prostate Cancer Using Multi-Targeted Recombinant Ad5 PSA/MUC1/Brachyury Based Immunotherapy Vaccines
National Cancer Institute (NCI)
NCT04498520 WITHDRAWN Abexinostat, Palbociclib, and Fulvestrant for the Treatment of Breast or Gynecologic Cancer
Pamela Munster
NCT02528357 COMPLETED GSK3174998 Alone and With Pembrolizumab in Participants With Advanced Solid Tumors (ENGAGE-1)
GlaxoSmithKline
NCT02499224 COMPLETED Safety and Pharmacokinetics Study of YYB101 in Advanced Solid Tumors Patients Who Are Refractory to Standard Therapy
CellabMED
NCT04419623 COMPLETED A Study of TL-895 With Standard Available Treatment Versus Standard Available Treatment for the Treatment of COVID-19 in Patients With Cancer
Telios Pharma, Inc.
NCT03009214 COMPLETED A Safety and Pharmacokinetic Phase I/Ib Study of AMC303 in Patients With Solid Tumours
amcure GmbH
NCT01409343 COMPLETED TrasGEX™: Phase 1 Study in Cancer Patients
Glycotope GmbH
NCT01976741 COMPLETED Dose Escalation Pan-FGFR (Fibroblast Growth Factor Receptor) Inhibitor (Rogaratinib)
Bayer
NCT03205176 COMPLETED AZD5153 in Patients With Relapsed or Refractory Solid Tumors, Including Lymphomas
AstraZeneca
NCT03234712 COMPLETED A Study Evaluating the Safety, Pharmacokinetics, and Anti-tumor Activity of ABBV-321 in Subjects With Advanced Solid Tumors Associated With Overexpression of the Epidermal Growth Factor Receptor (EGFR)
AbbVie
NCT01765790 COMPLETED Phase 1 Study of Anti-Macrophage Migration Inhibitory Factor (Anti-MIF) Antibody in Solid Tumors
Baxalta now part of Shire
NCT03706274 WITHDRAWN PROCLAIM-CX-188: A Trial to Find Safe and Active Doses of an Investigational Drug CX-188 for Patients With Solid Tumors
CytomX Therapeutics
NCT04868344 COMPLETED A Study of MRG003 in Patients With Advanced Solid Tumors
Shanghai Miracogen Inc.
NCT02817113 TERMINATED Study of NC-6004 in Combination With 5-FU and Cetuximab in Patients With Head and Neck Cancer
Orient Europharma Co., Ltd.
NCT03604679 COMPLETED SyB C-0501(Oral Bendamustine) in Patients With Advanced Solid Tumors
SymBio Pharmaceuticals
NCT03406364 COMPLETED Assess the Safety and Activity of Combined MG005 and Sorafenib (NEXAVAR®) Treatment With Solid Tumor
Metagone Biotech Inc.
NCT02608229 TERMINATED BVD-523 Plus Nab-paclitaxel and Gemcitabine in Patients With Metastatic Pancreatic Cancer
Washington University School of Medicine
NCT01065662 COMPLETED AZD2171 and Temsirolimus in Patients With Advanced Gynecological Malignancies
Susana M. Campos, MD
NCT02237638 COMPLETED Phase I Study on VEGF Vaccination in Metastatic Solid Tumors
Amsterdam UMC, location VUmc
NCT03495323 COMPLETED A Study of Prexasertib (LY2606368), CHK1 Inhibitor, and LY3300054, PD-L1 Inhibitor, in Patients With Advanced Solid Tumors
Dana-Farber Cancer Institute
NCT04162301 TERMINATED A Study of CS3002 in Subjects With Advanced Solid Tumors
CStone Pharmaceuticals
NCT02647671 COMPLETED Aquamin and Prevention of Colon Cancer
James Varani
NCT04839120 COMPLETED PK, PD, Tolerability and Safety of MDPK67b in Healthy Volunteers
Med Discovery SA
NCT03507543 COMPLETED The Safety and Pharmacokinetics of IMP4297 in Patients With Advanced Solid Tumors
Impact Therapeutics, Inc.
NCT03788603 COMPLETED Rogaratinib (BAY1163877) in Chinese Patients
Bayer
NCT02110355 COMPLETED A Phase 1b/2a Study Evaluating AMG 232 in Metastatic Melanoma
Kartos Therapeutics, Inc.
NCT03722186 SUSPENDED Safety, Tolerability and Pharmacokinetics/Pharmacodynamics (PK/PD) of SHR-1603 in Subjects With Advanced Malignancies
Jiangsu HengRui Medicine Co., Ltd.
NCT03449030 TERMINATED A Study of TAK-164 in Participants With Advanced Gastrointestinal (GI) Cancer Expressing Guanylyl Cyclase C (GCC)
Millennium Pharmaceuticals, Inc.
NCT03992326 TERMINATED Adoptive Transfer Of Autologous Tumor-Infiltrating Lymphocytes in Solid Tumors
Centre Hospitalier Universitaire Vaudois
NCT01938612 COMPLETED A Phase I, Open-Label, Multicentre Study to Evaluate the Safety, Tolerability and Pharmacokinetics of MEDI4736 in Patients With Advanced Solid Tumours
AstraZeneca
NCT04025307 TERMINATED Phase I Trial of bacTRL-IL-12 in Adult Subjects With Advanced, Treatment-refractory Solid Tumours
IQVIA Pty Ltd
NCT03213964 COMPLETED Intraperitoneal Delivery of Adaptive Natural Killer (NK) Cells (FATE-NK100) With Intraperitoneal Int
Masonic Cancer Center, University of Minnesota
NCT03113188 COMPLETED CBP501, Cisplatin and Nivolumab in Advanced Refractory Tumors
CanBas Co. Ltd.
NCT03134638 TERMINATED A Study of SY-1365 in Adult Patients With Advanced Solid Tumors
Syros Pharmaceuticals
NCT03515824 TERMINATED Study of MK-1697 in Participants With Advanced Solid Tumors (MK-1697-001)
Merck Sharp & Dohme LLC
NCT03318445 COMPLETED Rucaparib and Irinotecan in Cancers With Mutations in DNA Repair
Pamela Munster
NCT01624766 COMPLETED Everolimus and Anakinra or Denosumab in Treating Participants With Relapsed or Refractory Advanced Cancers
M.D. Anderson Cancer Center
NCT02997176 COMPLETED An Open-Label Pharmacokinetics and Safety Study of Talazoparib (MDV3800)
Pfizer
NCT02897765 COMPLETED A Personal Cancer Vaccine (NEO-PV-01) w/ Nivolumab for Patients With Melanoma, Lung Cancer or Bladder Cancer
BioNTech US Inc.
NCT01322802 COMPLETED Vaccine Therapy in Treating Patients With Stage III-IV or Recurrent Ovarian Cancer
University of Washington
NCT04338724 COMPLETED A Phase I Study of CS1002 in Subjects With Advanced Solid Tumors
CStone Pharmaceuticals
NCT02740270 COMPLETED Phase I/Ib Study of GWN323 Alone and in Combination With PDR001 in Patients With Advanced Malignancies and Lymphomas
Novartis Pharmaceuticals
NCT01169532 COMPLETED Ridaforolimus and Vorinostat in Treating Patients With Advanced Solid Tumors or Lymphoma
Fox Chase Cancer Center
NCT02699749 COMPLETED A Study to Evaluate TAK-931 in Participants With Advanced Nonhematologic Tumors
Millennium Pharmaceuticals, Inc.
NCT03489369 COMPLETED Sym022 (Anti-LAG-3) in Patients With Advanced Solid Tumor Malignancies or Lymphomas
Symphogen A/S
NCT04274907 TERMINATED A Safety Study of Oral Venetoclax in Combination With Intravenous Pembrolizumab in Adult Participants With Previously Untreated Non-Small Cell Lung Cancer (NSCLC) With High Programmed Cell Death Ligand-1 (PD-L1) Expression
AbbVie
NCT00786669 COMPLETED A Pilot Study of the Addition of Bevacizumab to VOIT Regimen for Relapsed/Refractory Pediatric Solid Tumors
Children's Hospital Medical Center, Cincinnati
NCT02392793 COMPLETED Talazoparib Plus Irinotecan With or Without Temozolomide in Children With Refractory or Recurrent Solid Malignancies
St. Jude Children's Research Hospital
NCT04488016 COMPLETED A Study to Evaluate Relative Bioavailability, Proton Pump Inhibitor (PPI) (Rabeprazole) Effect, Food Effect and Particle Size Effect of New Acalabrutinib Tablet in Healthy Subjects
AstraZeneca
NCT03125200 TERMINATED Study of ADCT-502 in Patients With Advanced Solid Tumors Withhuman Epidermal Growth Factor Receptor-2 (HER2) Expression
ADC Therapeutics S.A.
NCT02132754 COMPLETED Study of MK-4166 and MK-4166 in Combination With Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-4166-001)
Merck Sharp & Dohme LLC
NCT01878890 COMPLETED Phase I Dose Escalation Trial of Efavirenz in Solid Tumours or Non-Hodgkin Lymphoma in Therapeutic Failure.
Institut Bergonié
NCT04675021 COMPLETED Absolute Bioavailability and ADME Study of Savolitinib in Healthy Male Subjects
AstraZeneca
NCT01183559 COMPLETED A Trial of ZD6474, Paclitaxel, Carboplatin, 5-Fluorouracil, and Radiation Therapy Followed by Surgery
Fox Chase Cancer Center
NCT01531361 COMPLETED Vemurafenib With Sorafenib Tosylate or Crizotinib in Treating Patients With Advanced Malignancies With BRAF Mutations
M.D. Anderson Cancer Center
NCT01197170 COMPLETED Hormone Receptor Positive Disease Across Solid Tumor Types: A Phase I Study of Single-Agent Hormone Blockade and Combination Approaches With Targeted Agents to Provide Synergy and Overcome Resistance
M.D. Anderson Cancer Center
NCT01302808 COMPLETED Romidepsin and Erlotinib Hydrochloride in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer
University of Texas Southwestern Medical Center
NCT02866916 WITHDRAWN Study of SXL01 in Patients With Metastatic Castration-Resistant Prostate Cancer (PROSTIRNA)
Institut Claudius Regaud
NCT03760614 WITHDRAWN A Study of Entinostat and FOLFOX in Subjects With Pancreatic Adenocarcinoma
Abramson Cancer Center at Penn Medicine
NCT02900157 COMPLETED Study to Evaluate the Safety and Pharmacokinetics of MEDI9090 in Subjects With Advanced Solid Tumors
MedImmune LLC
NCT03736850 COMPLETED Study of CS3006 in Subjects With Locally Advanced or Metastatic Solid Tumors
CStone Pharmaceuticals
NCT02721043 COMPLETED Safety and Immunogenicity of Personalized Genomic Vaccine to Treat Malignancies
Nina Bhardwaj
NCT02997163 COMPLETED An Open-Label Pharmacokinetics and Safety Study of Talazoparib
Pfizer
NCT04275960 COMPLETED Study in Healthy Adult Male Participants to Gather Information How the Human Body Absorbs, Distributes and Excretes the Study Drug Selitrectinib Including the Effect of the Interaction of Food With the Study Drug on the Human Body
Bayer
NCT02392611 COMPLETED Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Alobresib (Formerly GS-5829) in Adults With Advanced Solid Tumors and Lymphomas and in Combination With Exemestane or Fulvestrant in Adults With Estrogen Receptor Positive Breast Cancer
Gilead Sciences
NCT03708211 COMPLETED A Study to Assess the Relative Bioavailability, Effect of Food, and Gastric Potential Hydrogen (pH) Modification on the Pharmacokinetics (PK) of TAK-931 in Participants With Advanced Solid Tumors
Millennium Pharmaceuticals, Inc.
NCT02608125 TERMINATED A Dose Escalation Study in Solid Tumors and a Dose Expansion Study of PRN1371 in Adult Patients With Metastatic Urothelial Carcinoma
Principia Biopharma, a Sanofi Company
NCT03162562 TERMINATED The Safety and Antitumor Activity of the Combination of Oregovomab and Hiltonol in Recurrent Advanced Ovarian Cancer
CanariaBio Inc.
NCT03096340 TERMINATED Safety and Pharmacokinetic Study of IT-141 in Monotherapy in Patients With Advanced Cancer
Intezyne Technologies, Inc.
NCT01482156 COMPLETED Dose Finding Study of RAD001 (Everolimus, Afinitor®) in Combination With BEZ235 in Patients With Advanced Solid Tumors
Novartis Pharmaceuticals
NCT01421004 COMPLETED Bioequivalence of 2 Formulations of TKI258 in Patients With Advanced Solid Tumors
Novartis Pharmaceuticals
NCT01529307 TERMINATED First in Human Trial of TAS266 in Patients With Advanced Solid Tumors
Novartis Pharmaceuticals
NCT00715182 COMPLETED A Phase I/II Study to Assess the Safety and Efficacy of TKI258 for the Treatment of Refractory Advanced/Metastatic Renal Cell Cancer
Novartis Pharmaceuticals
NCT02703571 TERMINATED Study of Safety and Efficacy of Ribociclib and Trametinib in Patients With Metastatic or Advanced Solid Tumors
Novartis Pharmaceuticals
NCT01030055 COMPLETED Bioavailability and Food Effect Study of TKI258 (CSF Capsules vs. FMI Capsules)in Adult Patients With Advanced Solid Tumors
Novartis Pharmaceuticals
NCT01596647 COMPLETED Pharmacokinetic Drug-drug Interaction Study of Dovitinib (TKI258) in Patients With Advanced Solid Tumors
Novartis Pharmaceuticals
NCT01471548 COMPLETED Phase I Dose Escalating Study of TKI258
Novartis Pharmaceuticals
NCT01700270 COMPLETED Pharmacokinetic Drug-drug Interaction Study of Dovitinib (TKI258) in Patients With Advanced Solid Tumors.
Novartis Pharmaceuticals
NCT01443481 COMPLETED Pharmacokinetics (PK) of TKI258 in Cancer Patients With Normal and Impaired Hepatic Function
Novartis Pharmaceuticals
NCT01155713 COMPLETED Bioavailability and Food Effect Study of TKI258 (CSF Capsule vs. FMI Tablet) in Adult Patients With Advanced Solid Tumors
Novartis Pharmaceuticals
NCT00880308 COMPLETED Dose Finding and Safety of Oral LDE225 in Patients With Advanced Solid Tumors
Novartis Pharmaceuticals
NCT02375958 COMPLETED PCA062 in pCAD-positive Tumors.
Novartis Pharmaceuticals
NCT01208831 COMPLETED An East Asian Study of LDE225
Novartis Pharmaceuticals
NCT01324479 COMPLETED Study of INC280 in Patients With c-MET Dependent Advanced Solid Tumors
Novartis Pharmaceuticals
NCT01769768 COMPLETED Phase I Study to Evaluate the Effect of LDE225 on the Pharmacokinetics of Bupropion and Warfarin in Patients
Novartis Pharmaceuticals
NCT00997399 COMPLETED Study to Evaluate Panobinostat (DACi) Pharmacokinetics and Safety in Solid Tumors and Varying Renal Function
Novartis Pharmaceuticals
NCT01240655 COMPLETED A Study of LCL161 in Combination With Weekly Paclitaxel in Adult Patients With Advanced Solid Tumors
Novartis Pharmaceuticals
NCT01546428 COMPLETED A Phase I Study of INC280 in Japanese Patients With Advanced Solid Tumors
Novartis Pharmaceuticals
NCT01968915 COMPLETED Safety and Tolerability of Oral LCL161 in Japanese Adult Patients With Advanced Solid Tumors
Novartis Pharmaceuticals
NCT02925104 COMPLETED A Dose Escalation Study to Assess PK, Safety and Tolerability of INC280 When Taken With Food in cMET Dysregulated Advanced Solid Tumors.
Novartis Pharmaceuticals
NCT01576666 COMPLETED Phase Ib, Dose Escalation Study of Oral LDE225 in Combination With BKM120 in Patients With Advanced Solid Tumors
Novartis Pharmaceuticals
NCT01898845 COMPLETED A Phase I Study of LEE011 in Asian Patients
Novartis Pharmaceuticals
NCT01007968 COMPLETED Pharmacokinetics and Safety of Panobinostat in Patients With Advanced Solid Tumors and Various Degrees of Hepatic Function
Novartis Pharmaceuticals
NCT00739414 COMPLETED Dose-escalating Study of LBH589 in Adult Patients With Advanced Solid Tumors
Novartis Pharmaceuticals
NCT01106508 COMPLETED A Dose Finding and Safety Study of Oral LEQ506 in Patients With Advanced Solid Tumors
Novartis Pharmaceuticals
NCT02222922 COMPLETED A Study Of PF-06647020 For Adult Patients With Advanced Solid Tumors
Pfizer
NCT01237236 COMPLETED A Trial of LEE011 in Patients With Advanced Solid Tumors or Lymphoma.
Novartis Pharmaceuticals
NCT01911936 COMPLETED A Phase I Study of LJM716 in Japanese Patients With Advanced Solid Tumors
Novartis Pharmaceuticals
NCT02987166 COMPLETED HDCRT Plus Pembrolizumab in Advanced Malignancies
James Larner, MD
NCT04109092 WITHDRAWN A Study of Stimulator of Interferon Genes (STING) Agonist E7766 in Non-muscle Invasive Bladder Cancer (NMIBC) Including Participants Unresponsive to Bacillus Calmette-Guerin (BCG) Therapy, INPUT-102
Eisai Inc.
NCT02626234 COMPLETED A Drug-drug Interaction (DDI) Study to Assess the Effect of INC280 on the Pharmacokinetics of Digoxin and Rosuvastatin in Patients With cMET-dysregulated Advanced Solid Tumors
Novartis Pharmaceuticals
NCT01905228 COMPLETED A Phase 1 Trial of CBL0137 in Patients With Metastatic or Unresectable Advanced Solid Neoplasm
Incuron
NCT02520752 COMPLETED A DDI Study to Assess the Effect of INC280 on the PK of Midazolam and Caffeine in Patients With cMET-dysregulated Advanced Solid Tumors
Novartis Pharmaceuticals
NCT01155453 COMPLETED A Study to Investigate Safety, Pharmacokinetics (PK) and Pharmacodynamics (PD) of BKM120 Plus GSK1120212 in Selected Advanced Solid Tumor Patients
Novartis Pharmaceuticals
NCT01278849 TERMINATED An Open-label, Dose Escalation Study to Assess the Pharmacokinetics of of ASA404 in Adult Cancer Patients With Impaired Hepatic Function
Novartis Pharmaceuticals
NCT01928459 COMPLETED Phase 1b Trial of BGJ398/BYL719 in Solid Tumors
Novartis Pharmaceuticals
NCT01240642 TERMINATED An Open-label, Dose Escalation Multi-center Study in Patients With Advanced Cancer to Determine the Infusion Rate Effect of ASA 404 With Paclitaxel Plus Carboplatin Regimen or Docetaxel on the Pharmacokietics of Free and Total ASA404
Novartis Pharmaceuticals
NCT01132625 COMPLETED Dose Escalation Study of AUY922 in Advanced Solid Malignancies in Japan
Novartis Pharmaceuticals
NCT01285466 COMPLETED A Trial of Oral BEZ235 and BKM120 in Combination With Paclitaxel With or Without Trastuzumab
Novartis Pharmaceuticals
NCT01195376 COMPLETED A Study of BEZ235 in Adult Japanese Patients With Advanced Solid Tumors
Novartis Pharmaceuticals
NCT01278758 TERMINATED A Dose-escalation Pharmacokinetic Study of Intravenous ASA404 in Adult Advanced Cancer Patients With Impaired Renal Function and Patients With Normal Renal Function
Novartis Pharmaceuticals
NCT01285453 COMPLETED Safety and Tolerability of ASA404 Administered in Combination With Docetaxel in Japanese Patients With Solid Tumors
Novartis Pharmaceuticals
NCT01064089 TERMINATED Dose Escalation of HSP990 in Japan/Korea
Novartis Pharmaceuticals
NCT01068483 COMPLETED Safety of BKM120 Monotherapy in Advanced Solid Tumor Patients
Novartis Pharmaceuticals
NCT02077933 COMPLETED Study of Safety and Efficacy of Alpelisib With Everolimus or Alpelisib With Everolimus and Exemestane in Advanced Breast Cancer Patients, Renal Cell Cancer and Pancreatic Tumors
Novartis Pharmaceuticals
NCT02051751 COMPLETED A Study to Evaluate the Potential Benefit of the Addition of BYL719 to Paclitaxel in the Treatment of Breast Cancer and Head-and-neck Cancer
Novartis Pharmaceuticals
NCT01387321 COMPLETED A Study of BYL719 in Adult Patients With Advanced Solid Malignancies
Novartis Pharmaceuticals
NCT02902237 COMPLETED tTF-NGR Phase I Study
University Hospital Muenster
NCT01283503 COMPLETED A Study of BKM120 in Adult Japanese Patients With Advanced Solid Tumors
Novartis Pharmaceuticals
NCT02798978 COMPLETED A Phase I, 2-part (Part 1 Being a Single Dose Escalation and Part 2, a Parallel Group) Study of Toll-like Receptor (TLR4) Agonist (GSK1795091) in Healthy Subjects
GlaxoSmithKline
NCT04195373 WITHDRAWN A Safety Study of TMV-018 in Patients With Tumors of the Gastrointestinal Tract
Themis Bioscience GmbH
NCT03790423 COMPLETED 18F-ASIS PET/CT Imaging of Tissue Factor Expression In Patients With Primary and Metastastic Cancer
Rigshospitalet, Denmark
NCT03976050 TERMINATED Phase I Study of HL-085 in Patients With Advanced Solid Tumors
Shanghai Kechow Pharma, Inc.
NCT02706535 COMPLETED A Cross-over Study to Evaluate the Effect of Itraconazole and Rifampicin on the Pharmacokinetics (PK) of GSK525762 in Healthy Female Subjects of Non Child Bearing Potential
GlaxoSmithKline
NCT00765973 COMPLETED Topotecan Liposomes Injection for Small Cell Lung Cancer (SCLC), Ovarian Cancer and Other Advanced Solid Tumors
Spectrum Pharmaceuticals, Inc
NCT04006301 COMPLETED First-in-Human Study of JNJ-74699157 in Participants With Tumors Harboring the KRAS G12C Mutation
Janssen Research & Development, LLC
NCT04142554 WITHDRAWN Parsaclisib in Newly Diagnosed Stage I-IIIC Triple Negative or HER2+ Breast Cancer
UNC Lineberger Comprehensive Cancer Center
NCT04274933 TERMINATED A Study to Evaluate the Safety and Tolerability of Venetoclax Tablets in Combination With Capecitabine Tablets in Adult Participants With Hormone Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer Who Had Disease Progression During or After CDK4/6 Inhibitor Therapy
AbbVie
NCT02595918 TERMINATED Nivolumab in Treating Patients With High-Risk Kidney Cancer Before Surgery
National Cancer Institute (NCI)
NCT03443622 WITHDRAWN Phase I Study of SC-43 Oral Solution in Subjects With Refractory Solid Tumors
SupremeCure Pharma Inc.
NCT02781805 TERMINATED Pilot Study of Bisphosphonates for Breast Cancer
University of Wisconsin, Madison
NCT02215096 COMPLETED Dose-finding Study of GSK2636771 When Administered in Combination With Enzalutamide in Male Subjects With Metastatic Castration-Resistant Prostate Cancer
GlaxoSmithKline
NCT03101280 COMPLETED A Combination Study of Rucaparib and Atezolizumab in Participants With Advanced Gynecologic Cancers and Triple-Negative Breast Cancer
Hoffmann-La Roche
NCT03226574 COMPLETED Study to Evaluate Safety and MTD of Epidural Resiniferatoxin Injection for Treatment of Intractable Cancer Pain
Sorrento Therapeutics, Inc.
NCT02138526 COMPLETED Pazopanib Tolerability When Given With Food
Radboud University Medical Center
NCT03272256 COMPLETED Phase 1 Study of IM156 in Patients With Advanced Solid Tumor and Lymphoma
ImmunoMet Therapeutics, Inc.
NCT01935973 COMPLETED Trametinib With or Without GSK2141795 in Treating Patients With Recurrent or Persistent Endometrial Cancer
National Cancer Institute (NCI)
NCT01432951 COMPLETED A Study of Enzastaurin in Chinese Patients With Advanced and/or Metastatic Solid Tumors or Lymphoma
Eli Lilly and Company
NCT01337765 COMPLETED Safety, Pharmacokinetics and Pharmacodynamics of BEZ235 Plus MEK162 in Selected Advanced Solid Tumor Patients
Pfizer
NCT01633970 COMPLETED A Study of Atezolizumab Administered in Combination With Bevacizumab and/or With Chemotherapy in Participants With Locally Advanced or Metastatic Solid Tumors
Genentech, Inc.
NCT00637702 COMPLETED A Study of ARRY-334543 in Patients With Advanced Cancer
Array Biopharma, now a wholly owned subsidiary of Pfizer
NCT03712423 COMPLETED PET Study With [89Zr]-Df-CriPec® Docetaxel
Amsterdam UMC, location VUmc
NCT00836888 COMPLETED ONO-4538 Phase I Study in Patients With Advanced Malignant Solid Tumors in Japan
Ono Pharmaceutical Co., Ltd.
NCT04577703 COMPLETED First-In-Human Phase I Trial of Ningetinib ( CT053PTSA ) in the Patients With Advanced Solid Tumors
Sunshine Lake Pharma Co., Ltd.
NCT02045602 COMPLETED Phase I Dose Escalation Study of Intravenous VCN-01 With or Without Gemcitabine and Abraxane® in Patients With Advanced Solid Tumors
Theriva Biologics SL
NCT00710736 COMPLETED A Study of ARRY-334543 and Capecitabine in Patients With Advanced Cancer
Array Biopharma, now a wholly owned subsidiary of Pfizer
NCT00833326 COMPLETED A Study of ARRY-334543 and Docetaxel in Patients With Advanced Cancer
Array Biopharma, now a wholly owned subsidiary of Pfizer
NCT01363232 COMPLETED Safety, Pharmacokinetics and Pharmacodynamics of BKM120 Plus MEK162 in Selected Advanced Solid Tumor Patients
Array Biopharma, now a wholly owned subsidiary of Pfizer
NCT01469130 COMPLETED A Phase I Study of Oral MEK162 in Japanese Patients With Advanced Solid Tumors
Array Biopharma, now a wholly owned subsidiary of Pfizer
NCT03189030 TERMINATED Study of Personalized Immunotherapy in Adults With Metastatic Colorectal Cancer
Aduro Biotech, Inc.
NCT03553108 COMPLETED A Study Using Olaparib Tablets for Subjects With Advanced Solid Tumours.
AstraZeneca
NCT01943461 COMPLETED Avelumab in Metastatic or Locally Advanced Solid Tumors (JAVELIN Solid Tumor JPN)
Merck KGaA, Darmstadt, Germany
NCT02476955 TERMINATED Open-label Phase 1b Study of ARQ 092 in Combination With Anastrozole
ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA)
NCT01352273 COMPLETED MEK162 and RAF265 in Adult Patients With Advanced Solid Tumors Harboring RAS or BRAFV600E Mutations
Array Biopharma, now a wholly owned subsidiary of Pfizer
NCT00881569 COMPLETED Extended Use Protocol for Participants With Cancer to Receive Continued Treatment With CS-7017
Daiichi Sankyo
NCT02919696 COMPLETED A Study of Abemaciclib (LY2835219) in Native Chinese Participants With Advanced and/or Metastatic Cancers
Eli Lilly and Company
NCT01999972 COMPLETED A Phase 1b Study Of Axitinib In Combination With Crizotinib In Patients With Advanced Solid Tumors
Pfizer
NCT02355535 COMPLETED Procaspase Activating Compound-1 (PAC-1) in the Treatment of Advanced Malignancies - Component 1
Vanquish Oncology, Inc.
NCT02429466 COMPLETED Study of the Hypomethylating Drug Guadecitabine (SGI-110) Plus Cisplatin in Relapsed Refractory Germ Cell Tumors
Nasser Hanna
NCT01219699 COMPLETED A Study of BYL719 in Adult Patients With Advanced Solid Malignancies, Whose Tumors Have an Alteration of the PIK3CA Gene
Novartis Pharmaceuticals
NCT01316822 COMPLETED A Study of ARRY-382 in Patients With Selected Advanced or Metastatic Cancers
Array Biopharma, now a wholly owned subsidiary of Pfizer
NCT01514123 COMPLETED Study of VGX-100 Administered Alone and Co-administered With Bevacizumab in Adult Subjects With Advanced Solid Tumors
Circadian Technologies Ltd.
NCT00959127 COMPLETED A Study of ARRY-438162 (MEK162) in Patients With Advanced Cancer
Array Biopharma, now a wholly owned subsidiary of Pfizer
NCT01649336 COMPLETED A Study of MEK162 and Paclitaxel in Patients With Epithelial Ovarian, Fallopian Tube or Peritoneal Cancer
Array Biopharma, now a wholly owned subsidiary of Pfizer
NCT02078349 COMPLETED Phase I Study of KPT330 in Asian Patients
National University Hospital, Singapore
NCT00744562 COMPLETED A Phase 1 Dose Escalation Study of OMP-21M18 in Subjects With Solid Tumors
OncoMed Pharmaceuticals, Inc.
NCT02622074 COMPLETED Safety and Efficacy Study of Pembrolizumab (MK-3475) in Combination With Chemotherapy as Neoadjuvant Treatment for Participants With Triple Negative Breast Cancer (TNBC) (MK-3475-173/KEYNOTE-173)
Merck Sharp & Dohme LLC
NCT01277146 COMPLETED A Dose Escalation Study of OMP-59R5 in Subjects With Solid Tumors
OncoMed Pharmaceuticals, Inc.
NCT03384316 COMPLETED Multi-Targeted Recombinant Ad5 (CEA/MUC1/Brachyury) Based Immunotherapy Vaccine Regimen in People With Advanced Cancer
National Cancer Institute (NCI)
NCT01957007 COMPLETED A Study of Vantictumab (OMP-18R5) in Combination With Docetaxel in Patients With Previously Treated NSCLC
OncoMed Pharmaceuticals, Inc.
NCT01345201 COMPLETED A Dose Escalation Study of OMP-18R5 in Subjects With Solid Tumors
OncoMed Pharmaceuticals, Inc.
NCT03375086 COMPLETED A Study of APX3330 in Patients With Advanced Solid Tumors
Apexian Pharmaceuticals, Inc.
NCT03961100 COMPLETED A Performance and Bioavailability Study of Entrectinib in Healthy Volunteers.
Genentech, Inc.
NCT03539484 TERMINATED A Study of RO7172508 in Patients With Locally Advanced and/or Metastatic CEA-Positive Solid Tumors
Hoffmann-La Roche
NCT03030287 COMPLETED A Phase 1b Study of OMP-305B83 Plus Paclitaxel in Subjects With Ovarian, Peritoneal or Fallopian Tube Cancer
OncoMed Pharmaceuticals, Inc.
NCT02916095 COMPLETED Kanitinib in Treating Patients With Advanced Solid Tumors
Beijing Konruns Pharmaceutical Co., Ltd.
NCT01953783 COMPLETED Mass Balance, Pharmacokinetics and Metabolism Study of IXAZOMIB
Millennium Pharmaceuticals, Inc.
NCT02121990 COMPLETED Dose-Escalation Study of Intraperitoneal (IP) Cisplatin, IV/IP Paclitaxel, IV Bevacizumab, and Oral Olaparib for Newly Diagnosed Ovarian, Primary Peritoneal, and Fallopian Tube Cancer
Memorial Sloan Kettering Cancer Center
NCT02658214 COMPLETED Durvalumab and Tremelimumab in Combination With First-Line Chemotherapy in Advanced Solid Tumors
AstraZeneca
NCT03008018 COMPLETED Safety,Tolerability and MTD KA2507 (HDAC6 Inhibitor) in Patients With Solid Tumours
Karus Therapeutics Limited
NCT03119428 TERMINATED A Study of OMP-313M32 in Subjects With Locally Advanced or Metastatic Solid Tumors
OncoMed Pharmaceuticals, Inc.
NCT02482441 COMPLETED A Phase 1a/b Dose Escalation Study of the Safety, Pharmacokinetics, and Pharmacodynamics of OMP-131R10
OncoMed Pharmaceuticals, Inc.
NCT02722954 COMPLETED A Phase 1b Study of Demcizumab Plus Pembrolizumab in Locally Advanced or Metastatic Solid Tumors
OncoMed Pharmaceuticals, Inc.
NCT03295942 TERMINATED A Study of OMP-336B11 in Subjects With Locally Advanced or Metastatic Tumors
OncoMed Pharmaceuticals, Inc.
NCT01608867 COMPLETED A Dose Escalation Study of OMP-54F28 in Subjects With Solid Tumors
OncoMed Pharmaceuticals, Inc.
NCT02298387 COMPLETED A Phase 1 Study of OMP-305B83 in Subjects With Solid Tumors
OncoMed Pharmaceuticals, Inc.
NCT01778439 COMPLETED A Dose Escalation Study of OMP-52M51 in Subjects With Solid Tumors
OncoMed Pharmaceuticals, Inc.
NCT02069145 COMPLETED Dose Escalation Study of OMP-54F28 in Combination With Sorafenib in Patients With Hepatocellular Cancer
OncoMed Pharmaceuticals, Inc.
NCT01425008 COMPLETED Study of MLN2480 in Participants With Relapsed or Refractory Solid Tumors Followed by a Dose Expansion in Participants With Metastatic Melanoma
Millennium Pharmaceuticals, Inc.
NCT02405065 COMPLETED Clinical Trial to Evaluate Safety, Tolerability and Pharmacokinetics and Anti-tumor Activity of HM95573
Hanmi Pharmaceutical Company Limited
NCT03118817 COMPLETED Expansion Study to Evaluate the Efficacy and Safety of HM95573 in BRAF, KRAS or NRAS Mutant Solid Cancers
Hanmi Pharmaceutical Company Limited
NCT01832506 COMPLETED A Japanese Phase 1 Trial of c-Met Inhibitor MSC2156119J in Subjects With Solid Tumors
Merck KGaA, Darmstadt, Germany
NCT00717704 COMPLETED Solid Tumors Using Ixabepilone and Dasatinib
Medstar Health Research Institute
NCT01976910 COMPLETED Study of 4-Demethylcholesteryloxycarbonylpenclomedine (DM-CHOC-PEN) in Patients With Advanced Cancer"
DEKK-TEC, Inc.
NCT01048008 COMPLETED Study of 4-Demethylcholesteryloxycarbonylpenclomedine (DM-CHOC-PEN) in Patients With Advanced Cancer
DEKK-TEC, Inc.
NCT04260360 WITHDRAWN Trial of NanoDoce Intratumoral Injection in Renal Cell Carcinoma
NanOlogy, LLC
NCT04013048 COMPLETED Study to Evaluate the Mass Balance and Biotransformation of [14C]-Fluzoparib in Chinese Patients With Solid Tumor
Jiangsu HengRui Medicine Co., Ltd.
NCT02881138 COMPLETED A Study of RC48-ADC in Subjects With HER2-Positive Advanced Malignant Solid Tumors
RemeGen Co., Ltd.
NCT03511222 TERMINATED Vorolanib (X-82) Combined With Checkpoint Inhibitors in Patients With Solid Tumors
Washington University School of Medicine
NCT01249443 TERMINATED Paclitaxel and Carboplatin in Treating Patients With Metastatic or Recurrent Solid Tumors and HIV Infection
AIDS Malignancy Consortium
NCT03089645 COMPLETED MEDI5083 Alone and in Combination With Durvalumab, Tremelimumab, and/or Docetaxel.
MedImmune LLC
NCT01099631 COMPLETED IL-2 Expressing, Attenuated Salmonella Typhimurium in Unresectable Hepatic Spread
Masonic Cancer Center, University of Minnesota
NCT02924766 COMPLETED A Safety and Pharmacokinetics Study of Niraparib Plus an Androgen Receptor-Targeted Therapy in Men With Metastatic Castration-Resistant Prostate Cancer (BEDIVERE)
Janssen Research & Development, LLC
NCT02955251 COMPLETED A Study of ABBV-428, an Immunotherapy, in Subjects With Advanced Solid Tumors
AbbVie
NCT02212730 TERMINATED A Study Evaluating the Effect of Pembrolizumab (MK-3475) in Participants With Renal Cell Cancer (MK-3475-031)
Merck Sharp & Dohme LLC
NCT01525602 COMPLETED Safety Study of PLX3397 and Paclitaxel in Patients With Advanced Solid Tumors
Daiichi Sankyo
NCT03407976 TERMINATED Apatinib With Pembrolizumab in Previously Treated Advanced Malignancies
University of Utah
NCT03415126 COMPLETED A Study of ASN007 in Patients With Advanced Solid Tumors
Asana BioSciences
NCT01749397 COMPLETED Veliparib and Floxuridine in Treating Patients With Metastatic Epithelial Ovarian, Primary Peritoneal Cavity, or Fallopian Tube Cancer
National Cancer Institute (NCI)
NCT02348320 COMPLETED Safety and Immunogenicity of a Personalized Polyepitope DNA Vaccine Strategy in Breast Cancer Patients With Persistent Triple-Negative Disease Following Neoadjuvant Chemotherapy
Washington University School of Medicine
NCT01388335 COMPLETED A Drug Interaction Study to Assess the Effect of LY317615 on the Metabolic Pathway of Warfarin
Eli Lilly and Company
NCT01092689 WITHDRAWN The Role of Meat-borne Carcinogens in Pancreatic Cancer
University of Minnesota
NCT02812875 COMPLETED A Study of CA-170 (Oral PD-L1, PD-L2 and VISTA Checkpoint Antagonist) in Patients With Advanced Tumors and Lymphomas
Curis, Inc.
NCT01862328 COMPLETED Dose Escalation, Multi-arm Study of MLN4924 Plus Docetaxel, Gemcitabine, or Combination of Carboplatin and Paclitaxel in Participants With Solid Tumors
Millennium Pharmaceuticals, Inc.
NCT02317302 TERMINATED FDG Tumor Heterogeneity During Chemoradiation as a Predictor of Response in Patients With Cervical Cancer
Washington University School of Medicine
NCT01049061 COMPLETED A Study of MORAb-003 in Patients With Solid Tumor
Eisai Co., Ltd.
NCT03343613 TERMINATED A Study of LY3381916 Alone or in Combination With LY3300054 in Participants With Solid Tumors
Eli Lilly and Company
NCT02512237 TERMINATED A Dose-escalation Study of ARX788, IV Administered in Subjects With Advanced Cancers With HER2 Expression
Zhejiang Medicine Co., Ltd.
NCT03164603 COMPLETED NLG802 Indoleamine 2,3-Dioxygenase (IDO) Inhibitor in Advanced Solid Tumors
NewLink Genetics Corporation
NCT02881190 COMPLETED Study of RC48-ADC Administered Intravenously to Subjects With HER2-Positive in Advanced Malignant Solid Tumors
RemeGen Co., Ltd.
NCT01596140 COMPLETED Vemurafenib in Combination With Everolimus or Temsirolimus With Advanced Cancer
M.D. Anderson Cancer Center
NCT02837991 TERMINATED A Dose Escalation, Safety and Activity Study of CDX-014 in Patients With Renal Cell Carcinoma and Ovarian Clear Cell Carcinoma
Celldex Therapeutics
NCT02992977 TERMINATED Safety and Tolerability Study of AutoSynVax™ Vaccine in Subjects With Advanced Cancer
Agenus Inc.
NCT01803282 COMPLETED Study to Evaluate the Safety and Tolerability of Andecaliximab as Monotherapy and in Combination With Chemotherapy in Participants With Advanced Solid Tumors
Gilead Sciences
NCT03256331 TERMINATED Evaluate the Safety of BEL-X-HG in Advanced Cancer Patients
Belx Bio-Pharmaceutical (Taiwan) Corporation
NCT04332549 WITHDRAWN To Assess the Bioavailability and Safety of Paclitaxel Injection Concentrate for Suspension in Subjects With Locally Recurrent or Metastatic Breast Cancer
Sun Pharma Advanced Research Company Limited
NCT03235570 COMPLETED A Safety and Tolerability Study of Pemigatinib in Japanese Subjects With Advanced Malignancies - (FIGHT-102)
Incyte Corporation
NCT00739609 TERMINATED IDO Inhibitor Study for Relapsed or Refractory Solid Tumors
NewLink Genetics Corporation
NCT03644056 COMPLETED Dose-escalation Study of IMC-001 in Subject With Metastatic or Locally-advanced Solid Tumors
ImmuneOncia Therapeutics Inc.
NCT02648711 TERMINATED Alternative Dosing for CRLX101(NLG207) Alone, With Avastin and With mFOLFOX6 in Advanced Solid Tumors
NewLink Genetics Corporation
NCT04126668 COMPLETED A Study to Investigate the Food Effect on the Pharmacokinetics of CM082 Tablet in Chinese Healthy Volunteers
AnewPharma
NCT02507544 COMPLETED A Safety and Pharmacokinetic Study of TRX-818 Administered Orally to Patients With Advanced Cancer
TaiRx, Inc.
NCT03027284 COMPLETED A Study of Merestinib (LY2801653) in Japanese Participants With Advanced or Metastatic Cancer
Eli Lilly and Company
NCT03733587 COMPLETED GX-I7 With Cyclophosphamide in Patients With Metastatic or Recurrent Solid Tumors
Genexine, Inc.
NCT02223052 COMPLETED Bioequivalence & Food Effect Study in Patients With Solid Tumor or Hematologic Malignancies
Celgene
NCT03478995 COMPLETED Study to Evaluate Safety and Tolerability of GX-I7 in Patients With Locally Advanced or Metastatic Solid Tumors
Genexine, Inc.
NCT01643499 COMPLETED Genotype-guided Dosing of mFOLFIRINOX Chemotherapy in Patients With Previously Untreated Advanced Gastrointestinal Malignancies
University of Chicago
NCT01470365 COMPLETED 3-Dimensional Conformal Radiation Therapy or Intensity-Modulated Radiation Therapy in Treating Patients With Recurrent Tumors
Fox Chase Cancer Center
NCT00650572 COMPLETED A Study of ARRY-380 in Patients With Advanced HER2+ Cancer
Seagen Inc.
NCT02659631 TERMINATED PF-06671008 Dose Escalation Study in Advanced Solid Tumors
Pfizer
NCT03547388 COMPLETED Moderate Whole Body Hyperthermia for Patients Undergoing Re-irradiation for Head and Neck Cancer -Influence on the Tumor Microenvironment
Charite University, Berlin, Germany
NCT03677531 COMPLETED Video Distraction to Decrease Use of Sedation in Pediatric Participants During Radiation Therapy
OHSU Knight Cancer Institute
NCT03700294 TERMINATED Safety, Tolerability, Pharmacokinetics, and Antitumor Study of ADCT-601 to Treat Advanced Solid Tumors
ADC Therapeutics S.A.
NCT02316197 COMPLETED Clinical Phase I Study Investigating MSC2490484A, an Inhibitor of a DNA-dependent Protein Kinase, in Advanced Solid Tumors or Chronic Lymphocytic Leukemia
Merck KGaA, Darmstadt, Germany
NCT02162836 COMPLETED A Safety Study of JNJ-56021927 in Participants With Metastatic Castration-Resistant Prostate Cancer
Janssen Pharmaceutical K.K.
NCT01312376 TERMINATED Autologous T-Cells Combined With Autologous OC-DC Vaccine in Ovarian Cancer
Abramson Cancer Center at Penn Medicine
NCT02452775 TERMINATED Autologous OC-L Vaccine and Ovarian Cancer
Abramson Cancer Center at Penn Medicine
NCT03920839 WITHDRAWN INCMGA00012 Plus Chemotherapy in Participants With Advanced Solid Tumors (POD1UM-105)
Incyte Corporation
NCT02324257 COMPLETED A Study of RO6958688 in Participants With Locally Advanced and/or Metastatic Carcinoembryonic Antigen Positive Solid Tumors
Hoffmann-La Roche
NCT01548924 TERMINATED Determination of Dose of Antiangiogenic Multitargeted DOVITINIB (TKI258) Plus Paclitaxel in Patients With Solid Tumors
Centro Nacional de Investigaciones Oncologicas CARLOS III
NCT02529553 COMPLETED A Study of LY3076226 in Participants With Advanced or Metastatic Cancer
Eli Lilly and Company
NCT01831089 COMPLETED Phase I Study of Lurbinectedin (PM01183) in Combination With Paclitaxel, With or Without Bevacizumab, in Selected Advanced Solid Tumors
PharmaMar
NCT02665416 COMPLETED Study Evaluating the Safety, Pharmacokinetics (PK), Pharmacodynamics (PD), and Therapeutic Activity of Selicrelumab (RO7009789) With Vanucizumab or Bevacizumab in Participants With Metastatic Solid Tumors
Hoffmann-La Roche
NCT02363829 COMPLETED A Study of Nelfinavir Added to Cisplatin Chemotherapy Concurrent With Pelvic Radiation for Locally Advanced Cervical Cancer (II-IVA)
Abramson Cancer Center at Penn Medicine
NCT04118842 COMPLETED A Study in Healthy Subjects to Assess the Pharmacokinetics of Savolitinib When Administered Alone and in Combination With Rifampicin
AstraZeneca
NCT00921739 COMPLETED Esophageal Sparing Intensity-modulated Radiation Therapy (IMRT) for Locally-Advanced Thoracic Malignancies
Duke University
NCT01383668 WITHDRAWN Sirolimus and Gold Sodium Thiomalate in Treating Patients With Advanced Squamous Non-Small Cell Lung Cancer
Mayo Clinic
NCT02124148 COMPLETED A Study of Prexasertib (LY2606368) With Chemotherapy or Targeted Agents in Participants With Advanced Cancer
Eli Lilly and Company
NCT02157792 COMPLETED M6620 First in Human Study
EMD Serono Research & Development Institute, Inc.
NCT03680560 TERMINATED Study of ACTR T Cell Product in Combination With Trastuzumab in Subjects With HER2-Positive Advanced Solid Tumor Cancers
Cogent Biosciences, Inc.
NCT04057729 COMPLETED IMP4297 Food Effect Trial in Healthy Volunteers
Impact Therapeutics, Inc.
NCT01536054 COMPLETED Sirolimus and Vaccine Therapy in Treating Patients With Stage II-IV Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cavity Cancer
Roswell Park Cancer Institute
NCT02540551 TERMINATED Sentinel Node Detection in Ovarian Cancer
Maastricht University Medical Center
NCT01393990 COMPLETED A Study of LY2228820 in Participants With Advanced Cancer
Eli Lilly and Company
NCT02884726 COMPLETED Phase 1 Study of Mesothelin-ADC
Bristol-Myers Squibb
NCT01502800 COMPLETED Clinical Trial of ARQ 761 in Advanced Solid Tumors
University of Texas Southwestern Medical Center
NCT01254617 COMPLETED Lenalidomide and Cetuximab in Treating Patients With Advanced Colorectal Cancer or Head and Neck Cancer
National Cancer Institute (NCI)
NCT00692900 COMPLETED Safety Study Involving Oxaliplatin With Docetaxel for Recurrent Ovarian,Primary Peritoneal, and Fallopian Tube Cancer
University of Pittsburgh
NCT02681796 COMPLETED Epidural Analgesia Use in Pancreatic Resections
Washington University School of Medicine
NCT02082626 TERMINATED Study of Eribulin in Children With Cancer to Determine Safety
University of Oklahoma
NCT02946671 COMPLETED Study of Pre-operative Combination Therapy With Mogamulizumab and Nivolumab Against Solid Cancer Patients
Osaka University
NCT02261220 COMPLETED A Phase 1 Study of MEDI4736 in Combination With Tremelimumab in Subjects With Advanced Solid Tumors
MedImmune LLC
NCT03277209 TERMINATED To Assess the Safety of Continuous IV Administration of Plerixafor and Assess Impact on the Immune Microenvironment in Patients With Pancreatic, Ovarian and Colorectal Adenocarcinomas
Weill Medical College of Cornell University
NCT01621217 COMPLETED Phase I Study of Cetuximab in Combination With 5-fluoruracil, Mitomycin C and Radiotherapy in Patients With Anal Cancer Stage T2 (>4 cm) - T4 N0-3 M0 or Any T N2-3 M0
Lund University Hospital
NCT03242993 COMPLETED [18F]-AZAFOL AS POSITRON EMISSION TOMOGRAPHY (PET) TRACER in FR Positive Cancer Imaging
University of Lausanne Hospitals
NCT02551185 COMPLETED ACY 241 in Combination With Paclitaxel in Patients With Advanced Solid Tumors
Celgene
NCT02082977 TERMINATED A Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of GSK2816126 in Subjects With Relapsed/Refractory Diffuse Large B Cell Lymphoma, Transformed Follicular Lymphoma, Other Non-Hodgkin's Lymphomas, Solid Tumors and Multiple Myeloma
GlaxoSmithKline
NCT01564251 COMPLETED A Study of GDC-0575 Alone and in Combination With Gemcitabine in Participants With Refractory Solid Tumors or Lymphoma
Genentech, Inc.
NCT02466802 COMPLETED Study of Regorafenib and Sildenafil for Advanced Solid Tumors
Virginia Commonwealth University
NCT03258515 COMPLETED A Study to Investigate the Effect of Single Dose of AZD6094 (600 mg) on Cardiac Repolarization in Healthy Volunteers
AstraZeneca
NCT03425773 COMPLETED Safety and Tolerability Evaluation Study of BVAC-B in Patients With HER2/Neu(Human Epithelial Growth Factor Receptor 2) Positive Gastric Cancer After Failure to Standard Care
Cellid Co., Ltd.
NCT02590952 COMPLETED A Phase I Study of Epitinib(HMPL-813) in Patients With Advanced Solid Tumors
Hutchison Medipharma Limited
NCT02601248 COMPLETED Study of Theliatinib (HMPL-309) in Patients With Advanced Solid Tumor
Hutchison Medipharma Limited
NCT02630251 TERMINATED Dose Escalation Study of GSK2820151 in Subjects With Advanced or Recurrent Solid Tumors
GlaxoSmithKline
NCT02092792 COMPLETED A Study Evaluating the Safety of Escalating Doses of DLYE5953A in Patients With Refractory Solid Tumors
Genentech, Inc.
NCT02650713 COMPLETED A Study of the Safety, Pharmacokinetics, and Therapeutic Activity of RO6958688 in Combination With Atezolizumab in Participants With Locally Advanced and/or Metastatic Carcinoembryonic Antigen (CEA)-Positive Solid Tumors
Hoffmann-La Roche
NCT03052205 COMPLETED A Study of Intratumoral IMO-2125 in Patients With Refractory Solid Tumors
Idera Pharmaceuticals, Inc.
NCT01114958 COMPLETED Pilot Study of Intra-Arterial Cisplatin With IV Thiosulfate in Patients With Lung Cancer or Lung Metastases
University of California, San Diego
NCT02576665 TERMINATED A Study of Toca 511, a Retroviral Replicating Vector, Combined With Toca FC in Patients With Solid Tumors or Lymphoma (Toca 6)
Tocagen Inc.
NCT03306420 TERMINATED First-in-Human Study of MS201408-0005A as Single Agent and in Combinations
EMD Serono Research & Development Institute, Inc.
NCT02219724 COMPLETED A Study to Assess Safety and Pharmacokinetics of MOXR0916 in Participants With Locally Advanced or Metastatic Solid Tumors
Genentech, Inc.
NCT02800889 WITHDRAWN Dose-Escalation Study of Pixantrone Monotherapy in Pediatric Patients With Relapsed or Refractory Cancer
CTI BioPharma
NCT01653470 COMPLETED Study to Evaluate Safety & Tolerability of BMS-906024 in Combination With Chemotherapy & to Define DLTs & MTD of BMS-906024 in Combination With One of the Following Chemotherapy Regimens; Weekly Paclitaxel, 5FU+Irinotecan or Carboplatin+Paclitaxel in Subjects With Advanced / Metastatic Solid Tumors
Bristol-Myers Squibb
NCT02383212 COMPLETED Study of REGN2810 (Anti-PD-1) in Patients With Advanced Malignancies
Regeneron Pharmaceuticals
NCT01292655 COMPLETED Study to Evaluate the Safety and Tolerability of IV Doses of BMS-906024 in Subjects With Advanced or Metastatic Solid Tumors
Bristol-Myers Squibb
NCT02743637 COMPLETED A Dose Escalation Study of SDX-7320 in Patients With Advanced Refractory or Late-Stage Solid Tumors
SynDevRx, Inc.
NCT03159585 COMPLETED To Evaluate the Efficacy of NY-ESO-1-specific T Cell Receptor Affinity Enhancing Specific T Cell in Solid Tumors
Zhujiang Hospital
NCT03676101 COMPLETED Evaluate the Safety and Primary Immunogenicity of 9-valent HPV Recombinant Vaccine in Chinese Healthy Females
Shanghai Bovax Biotechnology Co., Ltd.
NCT02647983 WITHDRAWN Multiparametric MRI for Prostate Cancer Localization and Characterization Using Hyperpolarized Pyruvate (13C) Injection
Sunnybrook Health Sciences Centre
NCT02350673 COMPLETED A Study of Intravenous (IV) Cergutuzumab Amunaleukin and Atezolizumab in Combination in Participants With Locally Advanced and/or Metastatic Solid Tumors
Hoffmann-La Roche
NCT02476552 COMPLETED Absorption, Metabolism, Excretion, and the Determination of Absolute Bioavailability of Niraparib in Subjects With Cancer
Tesaro, Inc.
NCT02620839 TERMINATED Phase Ib Study of Alpelisib With Cisplatin in Patients With HPV+ Solid Tumor Malignancies
Pamela Munster
NCT02358200 TERMINATED Study of BMN-673 With Carboplatin and Paclitaxel in Patients With Advanced BRCA-mutated Solid Tumor or Triple Negative Metastatic Breast Cancer
Pamela Munster
NCT03326986 COMPLETED Safety, Tolerability and Pharmacokinetics Study of MK-7252 in Healthy Adult Participants (MK-7252-001)
Merck Sharp & Dohme LLC
NCT01488513 COMPLETED ABC294640 in Treating Patients With Advanced Solid Tumors
RedHill Biopharma Limited
NCT01583777 COMPLETED Phase I Mass Balance, PK and Safety Study of 14C-Labeled Belinostat in Patients With Advanced Cancer
Acrotech Biopharma Inc.
NCT01165658 TERMINATED Study of Hypofractionated Proton Radiation Therapy in Thoracic Malignancies
M.D. Anderson Cancer Center
NCT02014116 TERMINATED A Study of LY3009120 in Participants With Advanced Cancer or Cancer That Has Spread to Other Parts of Their Body
Eli Lilly and Company
NCT01445522 COMPLETED ABT-888 Plus Metronomic Cyclophosphamide to Treat Cancer
National Cancer Institute (NCI)
NCT03042910 COMPLETED A Study to Assess the Effects of Talazoparib on Cardiac Repolarization in Patients With Advanced Solid Tumors
Pfizer
NCT01988896 COMPLETED Study of Atezolizumab in Combination With Cobimetinib in Participants With Locally Advanced or Metastatic Solid Tumors
Hoffmann-La Roche
NCT01287130 COMPLETED AZD6244 With Cetuximab for Solid Tumors and Colorectal Cancer
National Cancer Institute (NCI)
NCT01336985 TERMINATED Safety and Pharmacokinetics of Treating Liver Cancer With Drug-Eluting Beads
National Institutes of Health Clinical Center (CC)
NCT01445405 COMPLETED Radiation Therapy and Bortezomib and Cetuximab With or Without Cisplatin to Treat Head and Neck Cancer
National Cancer Institute (NCI)
NCT01237067 COMPLETED Olaparib in Combination With Carboplatin for Refractory or Recurrent Women s Cancers
National Cancer Institute (NCI)
NCT02304393 COMPLETED A Study of Selicrelumab (RO7009789) in Combination With Atezolizumab in Participants With Locally Advanced and/or Metastatic Solid Tumors
Hoffmann-La Roche
NCT01295827 COMPLETED Study of Pembrolizumab (MK-3475) in Participants With Progressive Locally Advanced or Metastatic Carcinoma, Melanoma, or Non-small Cell Lung Carcinoma (P07990/MK-3475-001/KEYNOTE-001)
Merck Sharp & Dohme LLC
NCT02134197 TERMINATED Dose-escalation Study of Lupartumab Amadotin (BAY1129980)
Bayer
NCT04193319 COMPLETED Effect of Fluconazole on PK of Fluzoparib in Healthy Male Subjects
Jiangsu HengRui Medicine Co., Ltd.
NCT01954355 COMPLETED LDE225 and Paclitaxel in Solid Tumors
Swiss Cancer Institute
NCT02075112 COMPLETED Soy Isoflavone in Combination With Radiation Therapy and Cisplatin in SCC of the Head and Neck
Emory University
NCT02391480 COMPLETED A Study Evaluating the Safety and Pharmacokinetics of ABBV-075 in Subjects With Cancer
AbbVie
NCT02614456 COMPLETED Combination of Interferon-gamma and Nivolumab for Advanced Solid Tumors
Fox Chase Cancer Center
NCT00985868 COMPLETED AT9283 in Children and Adolescents With Relapsed and Refractory Solid Tumors
Cancer Research UK
NCT01770353 COMPLETED MM-398 (Nanoliposomal Irinotecan, Nal-IRI) to Determine Tumor Drug Levels and to Evaluate the Feasibility of Ferumoxytol Magnetic Resonance Imaging to Measure Tumor Associated Macrophages and to Predict Patient Response to Treatment
Ipsen
NCT02071537 COMPLETED Chloroquine in Combination With Carboplatin/Gemcitabine in Advanced Solid Tumors
University of Cincinnati
NCT02751918 COMPLETED Phase Ib Study of Anetumab Ravtansine in Combination With Pegylated Liposomal Doxorubicin in Patients With Recurrent Mesothelin-expressing Platinum-resistant Cancer
Bayer
NCT01585415 TERMINATED Vemurafenib and White Blood Cell Therapy for Advanced Melanoma
National Cancer Institute (NCI)
NCT02679131 TERMINATED To Evaluate Safety and Pharmacokinetics of Belinostat in Patients Who Have Mild, Moderate and Severe Renal Impairment.
Acrotech Biopharma Inc.
NCT00674024 COMPLETED Pazopanib to Treat Adults With Advanced Cancers and Varying Degrees of Liver Function
National Cancer Institute (NCI)
NCT00859118 COMPLETED Pharmacodynamic Study of Axitinib in Patients With Advanced Solid Malignancies
University of Wisconsin, Madison
NCT00652626 COMPLETED Pharmacokinetics and Safety Study of Azacitidine in Cancer Patients With and Without Impaired Renal Function
Celgene
NCT02518958 COMPLETED A Phase I, Open-Label, Multiple Ascending Dose Study of RRx-001 and Nivolumab
EpicentRx, Inc.
NCT02586987 COMPLETED A Study to Assess the Safety, Tolerability and Anti-tumour Activity of Ascending Doses of Selumetinib in Combination With MEDI4736 and Selumetinib in Combination With MEDI4736 and Tremelimumab in Patients With Advanced Solid Tumours
AstraZeneca
NCT00747474 COMPLETED Phase I Study of Intravenous Lipotecan® (TLC388 HCl for Injection) in Patients With Advanced Solid Tumors
Taiwan Liposome Company
NCT02146222 COMPLETED VEGFR/PDGFR Dual Kinase Inhibitor X-82 and Docetaxel in Treating Patients With Solid Tumors
University of Wisconsin, Madison
NCT03057366 COMPLETED A Study of [14 C]-Pevonedistat in Participants With Advanced Solid Tumors
Millennium Pharmaceuticals, Inc.
NCT01251926 COMPLETED EZN-2208 (Pegylated SN-38) in Combination With Bevacizumab in Refractory Solid Tumors
National Cancer Institute (NCI)
NCT01163071 TERMINATED A Phase 1 Trial of ABI-011 in Patients With Advanced Solid Tumors or Lymphomas
Celgene
NCT00878189 COMPLETED A Trial In Patients With Advanced Cancer And Leukemia
Pfizer
NCT00848718 COMPLETED A Phase I Study of MK-2206 in Combination With Standard Chemotherapy in Participants With Locally Advanced or Metastatic Solid Tumors (MK-2206-003)
Merck Sharp & Dohme LLC
NCT01478685 COMPLETED A Phase 1 Study of CC-486 as a Single Agent and in Combination With Carboplatin or ABI-007 in Subjects With Relapsed or Refractory Solid Tumors
Celgene
NCT02288507 WITHDRAWN Sorafenib Concurrent With Yttrium-90 Transarterial Radioembolization in Patients With Advanced Hepatocellular Cancer
University of Hawaii
NCT02661815 TERMINATED A Phase 1b Study of Paclitaxel And Ricolinostat For The Treatment Of Gynecological Cancer
Dana-Farber Cancer Institute
NCT03126864 TERMINATED Study of Adoptive Cellular Therapy Using Autologous T Cells Transduced With Lentivirus to Express a CD33 Specific Chimeric Antigen Receptor in Patients With Relapsed or Refractory CD33-Positive Acute Myeloid Leukemia
M.D. Anderson Cancer Center
NCT02553499 TERMINATED Study of MK-1248 With and Without Pembrolizumab (MK-3475) for Participants With Advanced Solid Tumors (MK-1248-001)
Merck Sharp & Dohme LLC
NCT02267707 TERMINATED Pharmacokinetic and Safety Study of Nab®-Paclitaxel (ABI-007) Plus Gemcitabine in Subjects With Advanced Pancreatic Cancer Who Have Cholestatic Hyperbilirubinemia
Celgene
NCT00915083 COMPLETED A Phase I Study to Assess the Safety, Pharmacokinetics, and Potential Effects of Amrubicin on the QT/QTc Interval in Cancer Patients With Advanced Solid Tumors.
Celgene
NCT02857166 COMPLETED Study of JS001 in Participants With Advanced Solid Tumors
Shanghai Junshi Bioscience Co., Ltd.
NCT02221882 COMPLETED A Study of LY3164530 in Participants With Cancer
Eli Lilly and Company
NCT03619616 COMPLETED Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Single Ascending Dose of ZSP1603 in Healthy Adults
Guangdong Zhongsheng Pharmaceutical Co., Ltd.
NCT02471846 COMPLETED A Study of GDC-0919 and Atezolizumab Combination Treatment in Participants With Locally Advanced or Metastatic Solid Tumors
Genentech, Inc.
NCT03120130 SUSPENDED Study of Amblyomin-X in Advanced Solid Tumor
União Química Farmacêutica Nacional S/A
NCT01004224 COMPLETED A Dose Escalation Study in Adult Patients With Advanced Solid Malignancies
Novartis Pharmaceuticals
NCT01184326 COMPLETED Expanded Phase I Pazopanib and Everolimus in Advanced Solid Tumors and Previously Treated Advanced Urothelial Cancer
Dana-Farber Cancer Institute
NCT01723475 COMPLETED First-in-man Dose Escalation Study of BAY2010112 in Patients With Prostate Cancer
Bayer
NCT02274623 COMPLETED Effect of CTAP101 Capsules on Ca/iPTH in Advanced Breast/Prostate Cancer Patients Treated With Denosumab/Zoledronic Acid
OPKO Health, Inc.
NCT02979392 TERMINATED Phase I Study of TENPA in Advanced Solid Cancer
Yung-Jue Bang
NCT00688415 COMPLETED Safety and Pharmacologic Study of VTX-2337 in Patients With Advanced Cancer
Celgene
NCT02559492 TERMINATED Itacitinib Combined With INCB024360 and/or Itacitinib Combined With INCB050465 in Advanced Solid Tumors
Incyte Corporation
NCT02259010 COMPLETED A Study to Evaluate the Effect of Itraconazole on the Pharmacokinetics of Alisertib in Participants With Advanced Solid Tumors or Relapsed/Refractory Lymphoma
Millennium Pharmaceuticals, Inc.
NCT01135563 COMPLETED Study of Vinblastine and Sirolimus in Children With Recurrent/Refractory Solid Tumours Including CNS Tumours
The Hospital for Sick Children
NCT02711345 TERMINATED A Phase I Clinical Study With Investigational Compound LTT462 in Adult Patients With Specific Advanced Cancers.
Novartis Pharmaceuticals
NCT02759666 COMPLETED A Phase I Trial of SHR3162 in Subjects With Advanced Solid Tumors
Atridia Pty Ltd.
NCT02745743 COMPLETED Phase I Trial of BAY1251152 for Advanced Blood Cancers
Bayer
NCT03182257 TERMINATED Study of ONO-7579 in Patients With Advanced Solid Tumors/ NTRK Gene Fusion Positive Advanced Solid Tumors
Ono Pharmaceutical Co., Ltd.
NCT01226485 COMPLETED A Study in Advanced Cancer
Eli Lilly and Company
NCT03081819 COMPLETED A Phase I Study of SH003 for Evaluate Safe Dose Range in Patients With Solid Cancer
Kyunghee University Medical Center
NCT03427073 TERMINATED A Phase I Dose-escalation Study of Subcutaneous ALM201 in Patients With Advanced Ovarian Cancer and Other Solid Tumours
Almac Discovery
NCT02250170 COMPLETED Safety and Biomarker of OPB-111077 in Subjects With Advanced Solid Tumor
Korea Otsuka Pharmaceutical Co., Ltd.
NCT02644278 COMPLETED First-in-Human Study of the Safety, Tolerability, and Pharmacokinetic/Pharmacodynamic Profile of VX-984 in Combination With Chemotherapy
EMD Serono Research & Development Institute, Inc.
NCT00858429 COMPLETED Yttrium Y 90 Glass Microspheres and Capecitabine in Treating Patients With Liver Cholangiocarcinoma or Liver Metastases
Northwestern University
NCT01924689 COMPLETED Safety Study of Intratumoral Injection of Clostridium Novyi-NT Spores to Treat Patients With Solid Tumors That Have Not Responded to Standard Therapies
BioMed Valley Discoveries, Inc
NCT02307240 COMPLETED Open Label, Multi-center Study to Assess the Safety, Tolerability and Pharmacokinetics of CUDC-907 in Subjects With Advanced/Relapsed Solid Tumors
Curis, Inc.
NCT02953197 COMPLETED 18F-FDG-PET Guided Dose-Painting With Intensity Modulated Radiotherapy in Oropharyngeal Tumours
Guy's and St Thomas' NHS Foundation Trust
NCT01375699 COMPLETED Doxorubicin With or Without Sildenafil, With Analysis of Cardiac Markers
Virginia Commonwealth University
NCT02705482 COMPLETED A Study to Evaluate MEDI0562 in Combination With Immune Therapeutic Agents in Adult Subjects With Advanced Solid Tumors
MedImmune LLC
NCT02748837 COMPLETED A Study of ERY974 in Patient With Advanced Solid Tumors
Chugai Pharmaceutical
NCT02387138 COMPLETED A Trial Assessing Several Schedules of Oral S-1 in Combination With a Fixed Dose of Oxaliplatin and Irinotecan
Institut du Cancer de Montpellier - Val d'Aurelle
NCT01868022 COMPLETED Study to Evaluate GSK3052230 in Combination With Paclitaxel and Carboplatin, or Docetaxel or as Single Agent in Subjects With Solid Malignancies and Deregulated Fibroblast Growth Factor (FGF) Pathway Signaling
GlaxoSmithKline
NCT00656123 COMPLETED Study of Colon GVAX and Cyclophosphamide in Patients With Metastatic Colorectal Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT02737072 TERMINATED A Study of LY2510924 and Durvalumab in Participants With Solid Tumors
Eli Lilly and Company
NCT01158404 COMPLETED Notch Inhibitor in Advanced Cancer
Eli Lilly and Company
NCT02629549 TERMINATED Intraoperative Imaging of Pituitary Adenomas by OTL
University of Pennsylvania
NCT03286296 COMPLETED LZM009 to Treat Patients With Advanced Solid Tumors
Livzon Pharmaceutical Group Inc.
NCT02778126 COMPLETED A Study of Prexasertib (LY2606368) in Participants With Advanced Cancer
Eli Lilly and Company
NCT02300610 COMPLETED Enzalutamide in Combination With Gemcitabine and Cisplatin in Bladder Cancer
H. Lee Moffitt Cancer Center and Research Institute
NCT00900614 COMPLETED Safety Study of APR-246 in Patients With Refractory Hematologic Cancer or Prostate Cancer
Aprea Therapeutics
NCT03494231 TERMINATED A Study of HLX06, a Humanized Monoclonal Antibody Targeting Human Vascular Endothelial Growth Factor Receptor-2 in Patients With Advanced Solid Tumors
Henlix, Inc
NCT02707328 TERMINATED Study To Establish Maximum Tolerated Dose (MTD) of Cyberknife in Patients With Un-Resectable Pancreas Cancer (TL002)
The Cooper Health System
NCT00969553 COMPLETED Dose Finding Study of BI 6727 (Volasertib) in Patients With Various Solid Cancers
Boehringer Ingelheim
NCT03677960 TERMINATED Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) Infection
Antiva Biosciences
NCT02389751 COMPLETED Ganetespib in Combination With Paclitaxel, Carboplatin, and Radiation Therapy in Treating Patients With Stage II-III Esophageal Cancer
M.D. Anderson Cancer Center
NCT01945710 COMPLETED An Open-label, Multicenter, Multiple Dose, Phase 1 Study to Establish the Maximum Tolerated Dose of E7389 Liposomal Formulation in Patients With Solid Tumors
Eisai Limited
NCT01639911 COMPLETED Phase I Study of MLN8237 and Pazopanib in Patients With Solid Tumors
University of Illinois at Chicago
NCT02004717 COMPLETED Phase 1 Study of DS-8895a in Subjects With Advanced Solid Tumors
Daiichi Sankyo Co., Ltd.
NCT02952989 TERMINATED A Safety Study of SGN-2FF for Patients With Advanced Solid Tumors
Seagen Inc.
NCT04026321 COMPLETED Single-dose Escalation Study of SQ-001 Infusion to Characterize the PK Profiles of Major Sentinel Compounds in Healthy Adult Volunteers in US
Livzon Pharmaceutical Group Inc.
NCT02058901 COMPLETED Study of High-dose, Intermittent Sunitinib in Patients With Solid Tumors.
Amsterdam UMC, location VUmc
NCT01621542 COMPLETED Clinical Study of WT2725 in Patients With Advanced Malignancies
Sumitomo Pharma America, Inc.
NCT01938443 COMPLETED A Dose Escalation Study to Assess Safety of GSK2256098 (FAK Inhibitor) in Combination With Trametinib (MEK Inhibitor) in Subjects With Advanced Solid Tumors
GlaxoSmithKline
NCT01281514 COMPLETED A Study of Carboplatin, PLD and Everolimus in Certain Gynecologic Cancer
Fox Chase Cancer Center
NCT01287598 COMPLETED BAY73-4506 Probe Substrate Study
Bayer
NCT01863485 COMPLETED Phase 1 Study of CM082 (X-82) Tablets in Advanced Cancer Patients in China
AnewPharma
NCT03188328 TERMINATED Safety, Tolerability, PK, Dosimetry, MTD and Preliminary Efficacy of Intra-lesionally Injected AvidinOX, Followed by IV Escalating Doses of [177Lu]DOTA-biotin in Pts With Injectable Solid Tumors or Lymphomas
Alfasigma S.p.A.
NCT03349255 TERMINATED Clinical Study of ET1402L1-CAR T Cells in AFP Expressing Hepatocellular Carcinoma
Aeon Therapeutics (Shanghai) Co., Ltd.
NCT01966445 COMPLETED Dose Escalation Study to Investigate the Safety, Pharmacokinetics, and Pharmacodynamics of GSK2849330 in Subjects With Advanced Her3-Positive Solid Tumors
GlaxoSmithKline
NCT02367352 TERMINATED Alisertib (MLN8237) in Combination With Weekly Paclitaxel in East Asian Patients With Advanced Solid Tumors
Millennium Pharmaceuticals, Inc.
NCT02047890 COMPLETED Japanese BAY1000394 Monotherapy Phase I Study
Bayer
NCT03313557 COMPLETED AZD1775 Continued Access Study to Assess Safety and Tolerability for Patients Enrolled in AZD1775 Clinical Pharmacology Studies
AstraZeneca
NCT01898078 COMPLETED Food Effect Study of Alisertib (MLN8237) in Participants With Advanced Solid Tumors or Lymphomas
Millennium Pharmaceuticals, Inc.
NCT02289196 COMPLETED Safety Study of Vx006 Vaccine in Solid Tumor Patients
Vaxon Biotech
NCT03362723 COMPLETED A Study to Investigate the Bioequivalence or Relative Bioavailability of Three New Idasanutlin Tablet Variants Following Oral Administration in Participants With Solid Tumors
Hoffmann-La Roche
NCT01648764 COMPLETED A Study of LY2334737 in Participants With Cancer That is Advanced and/or Has Spread
Eli Lilly and Company
NCT01288989 COMPLETED A Study of Anti-VEGFR-3 Monoclonal Antibody IMC-3C5 in Subjects With Advanced Solid Tumors
Eli Lilly and Company
NCT02642016 COMPLETED A Study to Evaluate the Safety and Pharmacokinetics of CDX-0158 in Adult Patients With Advanced Solid Tumors
Celldex Therapeutics
NCT01212107 COMPLETED A Phase 1 Study of LY2874455 in Participants With Advanced Cancer
Eli Lilly and Company
NCT02476123 COMPLETED Study of Combination Therapy With Mogamulizumab (KW-0761) and Nivolumab (ONO-4538/BMS-936558) in Subjects With Advanced Solid Tumors
Kyowa Kirin Co., Ltd.
NCT01830816 COMPLETED Pharmacokinetics Study of Oral Ixazomib (MLN9708) in Relapsed/Refractory Multiple Myeloma and Advanced Solid Tumors Participants With Normal Renal Function or Severe Renal Impairment
Millennium Pharmaceuticals, Inc.
NCT02106845 COMPLETED Effect of Regorafenib on Digoxin and Rosuvastatin in Patients With Advanced Solid Malignant Tumors.
Bayer
NCT02309177 COMPLETED Safety Study of Nivolumab With Nab-Paclitaxel Plus or Minus Gemcitabine in Pancreatic Cancer, Nab-Paclitaxel / Carboplatin in Stage IIIB/IV Non-Small Cell Lung Cancer or Nab-Paclitaxel in Recurrent Metastatic Breast Cancer
Celgene
NCT02825563 COMPLETED A Phase I Study of Anlotinib on Pharmacokinetics to Assess the Effect of High Fat Diet in Advanced Cancer Patients
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT02324621 COMPLETED Continuation of Oral ONC201 in Treating Patients With Advanced Solid Tumors
Rutgers, The State University of New Jersey
NCT02250781 COMPLETED Oral ONC201 in Treating Patients With Advanced Solid Tumors
Rutgers, The State University of New Jersey
NCT02069158 COMPLETED Dose Finding Study Of PF-05212384 With Paclitaxel And Carboplatin In Patients With Advanced Solid Tumor
Cristiana Sessa
NCT01164709 COMPLETED Nelfinavir Mesylate and Bortezomib in Treating Patients With Relapsed or Progressive Advanced Hematologic Cancer
Swiss Cancer Institute
NCT01962532 COMPLETED A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of JNJ-42756493 in Patients With Advanced or Refractory Solid Tumors or Lymphoma
Janssen Research & Development, LLC
NCT03138408 TERMINATED SC-004 Alone or With ABBV-181 in Subjects With Epithelial Ovarian, Fallopian Tube, Primary Peritoneal and Endometrial Cancers
AbbVie
NCT03175497 COMPLETED Telatinib Safety and Pharmacokinetics Study in China Patients With Advanced Solid Tumors
Taizhou EOC Pharma Co., Ltd.
NCT00704821 TERMINATED PTC299 for Treatment of Advanced Cancer
PTC Therapeutics
NCT02160106 COMPLETED First in Human Dose Escalation Study of Vactosertib (TEW-7197) in Subjects With Advanced Stage Solid Tumors
MedPacto, Inc.
NCT00874731 COMPLETED A Study to Evaluate the Effect of MK-8669 (Ridaforolimus) on QTc Interval in Participants With Advanced Cancer (MK-8669-037)
Merck Sharp & Dohme LLC
NCT00858377 COMPLETED A Phase 1 First-in-Human Study Evaluating AMG 900 in Advanced Solid Tumors
Amgen
NCT01305512 COMPLETED Pharmacokinetic, Safety and Tolerability Study of SPARC1028
Sun Pharma Advanced Research Company Limited
NCT01304303 COMPLETED Pharmacokinetic and Safety Study of SPARC1023 Alone and in Carboplatin Combination
Sun Pharma Advanced Research Company Limited
NCT02622932 COMPLETED Study to Investigate the Absorption, Metabolism and Excretion of [14C] Anlotinib in Patients With Advanced Cancer Patients
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT02078752 TERMINATED A Study Of PF-06647263 In Patients With Advanced Solid Tumors
Pfizer
NCT00993512 COMPLETED Safety Study of Amphinex Based Photochemical Internalisation (PCI) of Bleomycin in Patients With Cutaneous Cancer
PCI Biotech AS
NCT01844947 COMPLETED Phase I Study With Sorafenib in Addition to Vinflunine in Metastatic Transitional Cell Carcinoma of the Urothelial Tract
Dr Anders Ullén
NCT01164956 TERMINATED Methylphenidate for Cancer-Related Fatigue
Dana-Farber Cancer Institute
NCT01877811 COMPLETED Study of RXDX-105, Potent RET Inhibitor in Patients With Advanced Lung Cancer and Other Solid Tumors
Hoffmann-La Roche
NCT02548390 TERMINATED Study of Intravenous RXDX-107 in Patients With Solid Tumors
Hoffmann-La Roche
NCT01791088 COMPLETED Sirolimus in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed By Surgery
University of Chicago
NCT02145559 COMPLETED A Pharmacodynamic Study of Sirolimus and Metformin in Patients With Advanced Solid Tumors
University of Chicago
NCT02540876 COMPLETED Ilorasertib in Treating Patients With CDKN2A-deficient Advanced or Metastatic Solid Cancers That Cannot Be Removed by Surgery
University of Chicago
NCT01380184 COMPLETED Pharmacokinetics of Ridaforolimus (MK-8669) in Chinese Participants (MK-8669-059)
Merck Sharp & Dohme LLC
NCT00909831 COMPLETED Hydroxychloroquine and Temsirolimus in Treating Patients With Metastatic Solid Tumors That Have Not Responded to Treatment
Abramson Cancer Center at Penn Medicine
NCT02672865 COMPLETED Adjuvant Hyperthermic Intraperitoneal Chemotherapy for Locally Advanced Gastric Cancer
Loma Linda University
NCT00761644 COMPLETED Doxil, Bevacizumab and Temsirolimus Trial
M.D. Anderson Cancer Center
NCT02105233 COMPLETED Improving Ultrasound Images in Brain Tumor Surgery With the Use of Brain Mimicking Fluid
St. Olavs Hospital
NCT00923390 TERMINATED Phase 1/2 Study of Metastatic Renal Cancer Using T-Cells Transduced With a T-Cell Receptor Which Recognizes TRAIL Bound to the DR4 Receptor
National Cancer Institute (NCI)
NCT01973868 COMPLETED Safety and Pharmacokinetics of Regorafenib and Cetuximab in Combination
Bayer
NCT01537107 COMPLETED Sirolimus and Vismodegib in Treating Patients With Solid Tumors or Pancreatic Cancer That is Metastatic or Cannot Be Removed By Surgery
Mayo Clinic
NCT02717572 COMPLETED 18F-FDG Uptake Measurements in Malignant Solid Tumors on PET/CT and PET/MR
Washington University School of Medicine
NCT02565758 COMPLETED ABBV-085, an Antibody Drug Conjugate, in Subjects With Advanced Solid Tumors
AbbVie
NCT00670488 COMPLETED Dose Escalation Study With MK-2206 in Patients With Locally Advanced or Metastatic Solid Tumors (MK-2206-002)
Merck Sharp & Dohme LLC
NCT03192943 COMPLETED A Study of BMS-986205 Given in Combination With Nivolumab in Patients With Advanced Tumors
Bristol-Myers Squibb
NCT01524224 COMPLETED A Dose-Escalation Study in Participants With Advanced Cancer
Eli Lilly and Company
NCT02129205 TERMINATED A Dose Escalation Study of PF-06650808 in Patients With Advanced Solid Tumors
Pfizer
NCT02703298 COMPLETED Safety and Pharmacokinetic Study of TRX-818 in Asian Solid Tumor Patients
TaiRx, Inc.
NCT01273155 COMPLETED Belinostat for Solid Tumors and Lymphomas in Patients With Varying Degrees of Hepatic Dysfunction
National Cancer Institute (NCI)
NCT01844583 COMPLETED Safety, Tolerability and Pharmacokinetic (PK) of Concomitant Esomeprazole and Rifampin, and QT Study on Single and Multiple-doses of Alisertib
Millennium Pharmaceuticals, Inc.
NCT01231594 COMPLETED A Rollover Study to Provide Continued Treatment With GSK2118436 to Subjects With BRAF Mutation-Positive Tumors
Novartis Pharmaceuticals
NCT02483858 COMPLETED Study of Oral PQR309 in Patients With Advanced Solid Tumors
PIQUR Therapeutics AG
NCT01209832 TERMINATED A Tasisulam and Midazolam Drug Interaction Study in Cancer Patients
Eli Lilly and Company
NCT00979134 TERMINATED Study is Designed to Assess the Safety and Tolerability of AZD4547 at Increasing Doses in Patients With Advanced Tumours
AstraZeneca
NCT01215916 COMPLETED A Phase 1 Study in Patients With Solid Tumors
Eli Lilly and Company
NCT01512758 COMPLETED A Study of Alisertib (MLN8237) in Adult East Asian Participants With Advanced Solid Tumors or Lymphomas
Millennium Pharmaceuticals, Inc.
NCT01490749 COMPLETED Trial of XELOX Followed by Radiation Combined With Carboplatin and RAD001 for Esophageal Cancer
Emory University
NCT02045095 TERMINATED A Dose Escalation Study of MLN7243 (TAK-243) in Adult Participants With Advanced Solid Tumors
Millennium Pharmaceuticals, Inc.
NCT03311477 COMPLETED A Study to Evaluate the Safety and Pharmacokinetics ABBV-399 in Japanese Participants With Solid Tumors
AbbVie
NCT02221960 COMPLETED A Phase 1 Study to Evaluate MEDI6383 Alone and in Combination With MEDI4736 in Adult Subjects With Select Advanced Solid Tumors
MedImmune LLC
NCT00962091 COMPLETED Study of MLN8237 in Participants With Advanced Solid Tumors
Millennium Pharmaceuticals, Inc.
NCT02813902 WITHDRAWN A Trial of Polypodium Leucotomos in Preventing Skin Cancer and Its Precursors
Massachusetts General Hospital
NCT02458339 COMPLETED Methotrexate Infusion Into Fourth Ventricle in Children With Recurrent Malignant Fourth Ventricular Brain Tumors
The University of Texas Health Science Center, Houston
NCT02745769 COMPLETED A Study in Advanced Cancers Using Ramucirumab (LY3009806) and Other Targeted Agents
Eli Lilly and Company
NCT00816361 COMPLETED A Dose-escalation Study to Evaluate the Safety, Tolerability, and Antitumor Activity of MEDI-573 in Subjects With Advanced Solid Tumors
MedImmune LLC
NCT01341457 COMPLETED A Study of LY2603618 in Combination With Gemcitabine in Participants With Solid Tumors
Eli Lilly and Company
NCT01431534 TERMINATED A Study of Ridaforolimus in Pediatric Participants With Advanced Solid Tumors (MK-8669-056)
Merck Sharp & Dohme LLC
NCT01713972 COMPLETED Dabrafenib and Pazopanib Hydrochloride in Treating Patients With Advanced Malignant Tumors
Manisha Shah
NCT02070406 TERMINATED Gene-Modified T Cells, Vaccine Therapy, and Ipilimumab in Treating Patients With Locally Advanced or Metastatic Malignancies
Jonsson Comprehensive Cancer Center
NCT02016729 COMPLETED A Phase 1b Study Evaluating AMG 232 Alone and in Combination With Trametinib in Acute Myeloid Leukemia
Kartos Therapeutics, Inc.
NCT02444793 TERMINATED A Study of PF-05082566 In Combination With Mogamulizumab In Patients With Advanced Solid Tumors
Pfizer
NCT02301754 COMPLETED INVAC-1 Anti-Cancer hTERT DNA Immunotherapy
Invectys
NCT02601274 TERMINATED Study of Theliatinib (HMPL-309) in Patients With Advanced Solid Tumor
Hutchison Medipharma Limited
NCT02973399 TERMINATED Efficacy and Safety of SNX-5422 Added to an Established Dose of Ibrutinib in CLL
Esanex Inc.
NCT02298946 COMPLETED AMP-224, a PD-1 Inhibitor, With Stereotactic Body Radiation Therapy in Metastatic Colorectal Cancer
National Cancer Institute (NCI)
NCT02688101 COMPLETED Dose-finding and Pharmacokinetic Study of DpC, Administered Orally to Patients With Advanced Solid Tumors
Collaborative Medicinal Development Pty Limited
NCT02345174 COMPLETED Immuno Positron Emission Tomography Study of GSK2849330 in Subjects With Human Epidermal Growth Factor Receptor 3-Positive Solid Tumors
GlaxoSmithKline
NCT01094288 COMPLETED A Phase 1 Study of Alisertib Participants With Advanced Solid Tumors Including Castration-Resistant Prostate Cancer Receiving a Standard Docetaxel Regimen
Millennium Pharmaceuticals, Inc.
NCT02555644 COMPLETED A Study of Prexasertib (LY2606368) With Chemotherapy and Radiation in Participants With Head and Neck Cancer
Eli Lilly and Company
NCT01119456 COMPLETED A Study of IMC-RON8 in Advanced Solid Tumors
Eli Lilly and Company
NCT01049893 COMPLETED Dose Finding, Safety and Tolerability Study for AC220 to Treat Advanced Solid Tumors
Daiichi Sankyo
NCT01588678 COMPLETED A Open-Label, Multiple Ascending Dose Study of DS-3078a, an Oral TORC1/2 Kinase Inhibitor, in Subjects With Advanced Solid Tumors or Lymphomas
Daiichi Sankyo
NCT02076451 COMPLETED Open-label Study of DS-8273a to Assess Its Safety and Tolerability, and Assess Its Pharmacokinetic and Pharmacodynamic Properties in Subjects With Advanced Solid Tumors or Lymphomas
Daiichi Sankyo
NCT01149720 COMPLETED Determination of the Relative Bioavailability of ARQ 197 Tablet Formulation With Capsule C Formulation as a Reference in Subjects With Advanced Solid Tumors
Daiichi Sankyo
NCT01517399 COMPLETED Drug-drug Interaction Study of Tivantinib (ARQ 197) With Omeprazole, S-warfarin, Caffeine, Midazolam, and Digoxin in Cancer Subjects
Daiichi Sankyo
NCT01699061 COMPLETED Effect of Tivantinib on the QTC Interval in Cancer Subjects
Daiichi Sankyo
NCT00697632 COMPLETED Safety Study of Oral MGCD265 Administered Without Interruption to Subjects With Advanced Malignancies
Mirati Therapeutics Inc.
NCT02150733 COMPLETED Pharmacokinetics of Tivantinib in Subjects With Advanced Solid Tumors and Hepatic Impairment
Daiichi Sankyo
NCT02179918 COMPLETED A Study Of 4-1BB Agonist PF-05082566 Plus PD-1 Inhibitor MK-3475 In Patients With Solid Tumors (B1641003/KEYNOTE-0036)
Pfizer
NCT03202992 COMPLETED Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) Infection
Antiva Biosciences
NCT03011320 COMPLETED An Exploratory Study of the Folic Acid-tubulysin Conjugate EC1456 in Ovarian Cancer Subjects Undergoing Surgery
Endocyte
NCT01999738 COMPLETED Folic Acid-Tubulysin Conjugate EC1456 In Patients With Advanced Solid Tumors
Endocyte
NCT02216409 COMPLETED Phase 1 Trial of Hu5F9-G4, a CD47-targeting Antibody
Gilead Sciences
NCT02731742 TERMINATED Dose Evaluation of MK-1966 in Combination With SD-101 in Participants With Advanced Malignancies (MK-1966-001)
Merck Sharp & Dohme LLC
NCT01206816 COMPLETED An Open Label Phase I Dose Escalation Trial of Intravenous BI 6727 (Volasertib)in Combination With Oral BIBW 2992 (Afatinib) in Patients With Advanced Solid Tumours
Boehringer Ingelheim
NCT00969761 COMPLETED BI 6727 (Volasertib) in Combination With Cisplatin or Carboplatin in Patients With Advanced or Metastatic Solid Tumour
Boehringer Ingelheim
NCT01858155 COMPLETED Phase I Dose Finding Study for Melatonin in Pediatric Oncology Patients With Relapsed Solid Tumors
C17 Council
NCT01145885 COMPLETED BI 6727 (Volasertib) Human ADME Trial in Various Solid Tumours
Boehringer Ingelheim
NCT02171221 COMPLETED Phase I Study of Oral DFP-11207 in Solid Tumors
Delta-Fly Pharma, Inc.
NCT01646203 COMPLETED A Study of IMC-TR1 in Participants With Advanced Solid Tumors
Eli Lilly and Company
NCT01394003 TERMINATED A Study of LY2584702 in Participants With Advanced Cancer
Eli Lilly and Company
NCT02582931 COMPLETED MRI-Guided Stereotactic Body Radiation Therapy (SBRT) for Ovarian Cancer
Washington University School of Medicine
NCT02418624 COMPLETED Phase I of Carboplatin-Olaparib Followed by Olaparib Monotherapy in Advanced Cancer
The Netherlands Cancer Institute
NCT02171260 COMPLETED This is a Phase 1 Study of Eribulin Mesylate in Pediatric Participants With Recurrent or Refractory Solid Tumors (Excluding [Central Nervous System] CNS), Including Lymphomas
Eisai Inc.
NCT02963389 COMPLETED A Study to Evaluate Safety, Tolerability, and Pharmacokinetics/Pharmacodynamics of Tripegfilgrastim in Pediatric Solid Tumor/Lymphoma Patients
Dong-A ST Co., Ltd.
NCT01286987 COMPLETED Study of Talazoparib, a PARP Inhibitor, in Patients With Advanced or Recurrent Solid Tumors
Pfizer
NCT01173913 COMPLETED Weekly Administration of (bi-)Daily Oral Docetaxel in Combination With Ritonavir
The Netherlands Cancer Institute
NCT01258348 COMPLETED A Phase 1b Trial in Patients With Renal Cell Cancer
Eli Lilly and Company
NCT01284335 TERMINATED A Safety Study in Participants With Advanced Solid Tumors
Eli Lilly and Company
NCT01891669 TERMINATED A Study Of PF-06263507 In Patients With Advanced Solid Tumors
Pfizer
NCT02583165 COMPLETED A Study in Adult Subjects With Select Advanced Solid Tumors
MedImmune LLC
NCT01457131 TERMINATED Modified White Blood Cells That Secrete IL-2 and Express a Protein That Targets the ESO-1tumor Protein for Metastatic Cancer
National Cancer Institute (NCI)
NCT02122770 COMPLETED Effects of Fluconazole and Itraconazole CYP3A-Mediated Inhibition on the Pharmacokinetics, Safety, and Tolerability of MLN4924 in Participants With Advanced Solid Tumors
Millennium Pharmaceuticals, Inc.
NCT01296568 COMPLETED C14 Study in Oncology Patients With Advanced and/or Metastatic Solid Tumors
Eli Lilly and Company
NCT03450109 COMPLETED A Study to Assess LY01005 Versus Goserelin Comparator (ZOLADEX®) in Patients With Prostate Cancer
Luye Pharma Group Ltd.
NCT01214668 COMPLETED Dose-Escalation Study of LY573636-sodium and Liposomal Doxorubicin in Patients With Advanced Solid Tumors
Eli Lilly and Company
NCT01938846 COMPLETED BI 860585 Dose Escalation Single Agent and in Combination With Exemestane or With Paclitaxel in Patients With Various Advanced and/or Metastatic Solid Tumors
Boehringer Ingelheim
NCT01923337 COMPLETED Irinotecan and Alisertib in Treating Patients With Advanced Solid Tumors or Colorectal Cancer
University of California, Davis
NCT01078649 COMPLETED Dose Escalation Study of Safety and Tolerability of AT-406 in Patients With Advanced Solid Tumors and Lymphomas
Debiopharm International SA
NCT02683395 TERMINATED A Study of PLX51107 in Advanced Malignancies
Plexxikon
NCT01324830 COMPLETED Monotherapy Dose Finding With BI 847325 in Solid Tumours
Boehringer Ingelheim
NCT02556463 TERMINATED A Study of MEDI9197 in Subjects With Solid Tumors or CTCL and in Combination With Durvalumab and/or Palliative Radiation in Subjects With Solid Tumors
MedImmune LLC
NCT01128842 COMPLETED A Study Of Neratinib (HKI-272) And Capecitabine In Japanese With Solid Tumor
Puma Biotechnology, Inc.
NCT03070548 COMPLETED A Study of Talazoparib in Patients With Advanced Solid Tumors
Pfizer
NCT02860780 COMPLETED A Study of Prexasertib (LY2606368) in Combination With Ralimetinib in Participants With Advanced or Metastatic Cancer
Eli Lilly and Company
NCT01386346 COMPLETED Epigenetic Priming Using Azacitidine With Neoadjuvant Chemotherapy for Resectable Esophageal Cancer
Weill Medical College of Cornell University
NCT01332721 COMPLETED Study of TRC105 Combined With Standard-Dose Bevacizumab for Advanced Solid Tumors for Which Bevacizumab is Indicated
Tracon Pharmaceuticals Inc.
NCT01116336 COMPLETED Phase I Chemoprevention Trial With Green Tea Polyphenon E & Erlotinib in Patients With Premalignant Lesions of the Head & Neck
Emory University
NCT03145909 TERMINATED A Study Evaluating the Safety, Pharmacokinetics and Anti-Tumor Activity of ABBV-176 in Subjects With Advanced Solid Tumors Likely to Express Prolactin Receptor (PRLR)
AbbVie
NCT03153163 COMPLETED Study of the Pharmacokinetics and Safety of Trastuzumab Emtansine in Chinese Participants With Locally Advanced Inoperable or Metastatic HER2+ Breast Cancer
Hoffmann-La Roche
NCT02245204 COMPLETED Phase I Studies of Chlorogenic Acid for Injection for Tolerance and Pharmacokinetic of Advanced Cancers
Sichuan J.Z. Bio-chemical Science and Technology Development Co., Ltd
NCT02966171 TERMINATED A Dose Escalation Study to Assess the Safety and Tolerability of HMPL-453 in Patients With Advanced Solid Malignancies
Hutchison Medipharma Limited
NCT00768469 COMPLETED Study Evaluating Safety And Tolerability, Solid Tumor
Puma Biotechnology, Inc.
NCT02214147 COMPLETED Pharmacokinetics of Alisertib in Adults With Advanced Solid Tumors or Relapsed/Refractory Lymphoma With Varying Degrees of Hepatic Function
Millennium Pharmaceuticals, Inc.
NCT02268825 TERMINATED Phase I Study MK-3475 With Chemotherapy in Patients With Advanced GI Cancers
University of Utah
NCT01086332 TERMINATED Evaluation of Nelfinavir and Chemoradiation for Pancreatic Cancer
University of Iowa
NCT03237416 COMPLETED Drug-drug-interaction Study to Assess the Effect of Darolutamide on the Pharmacokinetics of Probe Substrates of CYP3A4 and P-gp in Healthy Male Volunteers
Bayer
NCT00940498 COMPLETED Study of PF-05212384 (Also Known as PKI-587)Administered Intravenously To Subjects With Solid Tumors
Pfizer
NCT01764828 COMPLETED BAY86-9766 Plus Gemcitabine Phase I Study in Asian
Bayer
NCT01714947 COMPLETED Mass Balance, Pharmacokinetics and Metabolism Study of Alisertib
Millennium Pharmaceuticals, Inc.
NCT01347866 TERMINATED Clinical Study Of PI3K/mTOR Inhibitors In Combination With An Oral MEK Inhibitor Or Irinotecan In Patients With Advanced Cancer
Pfizer
NCT02648425 COMPLETED Safety and Tolerability of ASLAN001 in Combination With Cisplatin and 5-FU or Cisplatin and Capecitabine
ASLAN Pharmaceuticals
NCT01576406 COMPLETED Hepatic Impairment Study For Crizotinib In Advanced Cancer Patients
Pfizer
NCT01358968 COMPLETED A Drug Interaction Study to Assess the Effect of LY2603618 on the Metabolic Pathway of Desipramine
Eli Lilly and Company
NCT02636426 COMPLETED Sorafenib Administered Using a High-dose, Pulsatile Regimen: a Phase I Exposure Escalation Study
Amsterdam UMC, location VUmc
NCT00926640 COMPLETED A Phase I Study of Belinostat in Combination With Cisplatin and Etoposide in Adults With Small Cell Lung Carcinoma and Other Advanced Cancers
National Cancer Institute (NCI)
NCT01185548 TERMINATED A Drug Interaction Study of Tasisulam in Patients With Advanced Cancer or Lymphoma
Eli Lilly and Company
NCT02508441 TERMINATED Phase 1 Safety and Tolerability Study of Andes-1537 for Injection in Patients With Advanced Unresectable Solid Tumors
Andes Biotechnologies
NCT01240577 COMPLETED An Early Phase I Study of IPdR Absorption, Metabolism, and Safety in Patients With Advanced Solid Tumors and Lymphomas
National Cancer Institute (NCI)
NCT01833546 COMPLETED A Japanese Phase 1 Trial of TH-302 in Subjects With Solid Tumors and Pancreatic Cancer
Merck KGaA, Darmstadt, Germany
NCT01820325 TERMINATED Safety and Efficacy of Buparlisib (BKM120) in Patients With Untreated Squamous Non-small Cell Lung Cancer
Novartis Pharmaceuticals
NCT03496519 WITHDRAWN Assessing the Combination of Durvalumab (MEDI4736) and Trabectedin in Solid Tumors
University of Colorado, Denver
NCT01688206 COMPLETED A Study of Vanucizumab (RO5520985) Alone or in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors
Hoffmann-La Roche
NCT01986426 COMPLETED LTX-315 in Patients With Transdermally Accessible Tumours as Monotherapy or Combination With Ipilimumab or Pembrolizumab
Lytix Biopharma AS
NCT02845414 WITHDRAWN Study of CD133KDEL Toxin in the Treatment for Solid Tumors
Masonic Cancer Center, University of Minnesota
NCT03320525 TERMINATED Pharmacokinetic Profile of T-ChOS™ in Subjects With Advanced Solid Tumors (CHITIN)
Herlev Hospital
NCT02277392 WITHDRAWN A Phase-I, Dose Escalation Study of Recombinant Human Interleukin-18 (Sb-485232) Combined With Adoptive Transfer of Vaccine-Primed CD3/CD28-Costimulated Autologous T-Cells Following Lymphodepletion for Adult Patients With Recurrent Ovarian, Fallopian Tube or Primary Peritoneal Cancer
Abramson Cancer Center at Penn Medicine
NCT00997360 WITHDRAWN Study of PKI-179 Administered Orally to Subjects With Solid Tumors
Wyeth is now a wholly owned subsidiary of Pfizer
NCT00742105 TERMINATED Phase I Study to Determine the Maximum Tolerate Dose (MTD) of BGT226 in Advanced Solid Tumors in Japan
Novartis Pharmaceuticals
NCT02442531 COMPLETED A Study of CriPec® Docetaxel Given to Patients With Solid Tumours
Cristal Therapeutics
NCT01971515 COMPLETED First-in-Human Dose Escalation Trial in Subjects With Advanced Malignancies
EMD Serono
NCT00838539 COMPLETED Study Evaluating Neratinib In Combination With Temsirolimus In Subjects With Solid Tumors
Puma Biotechnology, Inc.
NCT02939846 WITHDRAWN Pharmacokinetics of Single and Repeat Oral Doses of Trametinib in Chinese Subjects With Solid Tumours
GlaxoSmithKline
NCT01497925 COMPLETED Ph 1 Trial of ADI-PEG 20 Plus Docetaxel in Solid Tumors With Emphasis on Prostate Cancer and Non-Small Cell Lung Cancer
Polaris Group
NCT02046421 COMPLETED Carboplatin, Gemcitabine Hydrochloride, and Mifepristone in Treating Patients With Advanced Breast Cancer or Recurrent or Persistent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer
University of Chicago
NCT02191761 COMPLETED Safety and Pharmacokinetics of SM04755 in Subjects With Advanced Colorectal, Gastric, Hepatic, or Pancreatic Cancer
Biosplice Therapeutics, Inc.
NCT02650635 TERMINATED TLR8 Agonist VTX-2337 and Cyclophosphamide in Treating Patients With Metastatic, Persistent, Recurrent, or Progressive Solid Tumors
Mayo Clinic
NCT01695733 TERMINATED Response to Influenza Vaccine in Patients With Non-Hematologic Malignancies Receiving Chemotherapy
Washington University School of Medicine
NCT01438554 COMPLETED Phase 1 Study of Pazopanib With GSK1120212 in Advanced Solid Tumors, Enriched With Patients With Differentiated Thyroid Cancer, Soft-tissue Sarcoma, and Cholangiocarcinoma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT00878111 COMPLETED Study of NGR-hTNF Administered at High Doses in Patient With Advanced or Metastatic Solid Tumour
AGC Biologics S.p.A.
NCT01303705 COMPLETED Anti-OX40, Cyclophosphamide (CTX) and Radiation in Patients With Progressive Metastatic Prostate Cancer
Providence Health & Services
NCT02134600 COMPLETED OmegaChild - Omega-3 Supplementation to Children Previously Treated for Cancer
Per Kogner
NCT01463696 TERMINATED Study of Safety and Pharmacokinetics of MK-8242 in Participants With Advanced Solid Tumors (P07650)
Merck Sharp & Dohme LLC
NCT00779584 COMPLETED A Dose-escalation Study of MK-8776 (SCH 900776) With and Without Gemcitabine in Participants With Solid Tumors or Lymphoma (MK-8776-002/P05248)
Merck Sharp & Dohme LLC
NCT00960063 TERMINATED A Study of Robatumumab (SCH 717454, MK-7454) in Combination With Different Treatment Regimens in Pediatric Participants With Advanced Solid Tumors (P05883, MK-7454-006)
Merck Sharp & Dohme LLC
NCT03330990 COMPLETED Evaluate the Effect of Entrectinib on the Pharmacokinetics of Midazolam in Cancer Patients
Hoffmann-La Roche
NCT01241461 COMPLETED A Study of LY2584702 in Solid Tumors
Eli Lilly and Company
NCT03285607 WITHDRAWN MCS110 Combined With Neoadjuvant Doxorubicin, Cyclophosphamide, and Weekly Paclitaxel in Patients With Hormone-Receptor Positive and HER2- Breast Cancer
Washington University School of Medicine
NCT01243762 TERMINATED A Study of Dalotuzumab + MK-2206, Dalotuzumab + MK-0752, and Dalotuzumab + Ridaforolimus Combination Therapies in Participants With Advanced Cancer (MK-0646-027)
Merck Sharp & Dohme LLC
NCT02759250 COMPLETED A Study of ARGX-110 in Patients With Nasopharyngeal Carcinoma (NPC)
argenx
NCT01021748 COMPLETED A Combination Therapy Study of MK-2206 and AZD6244 in Participants With Advanced Solid Tumors (MK-2206-010)
Merck Sharp & Dohme LLC
NCT01463631 COMPLETED A Study of LY3007113 in Participants With Advanced Cancer
Eli Lilly and Company
NCT01214642 COMPLETED A Dose-Escalation Study for Patients With Advanced Cancer
Eli Lilly and Company
NCT01348347 COMPLETED BI 6727 (Volasertib) Monotherapy Phase I Trial in Japanese Patients With Advanced Solid Tumours
Boehringer Ingelheim
NCT01647789 TERMINATED A Study of Oral CFG920 in Patients With Castration Resistant Prostate Cancer
Novartis Pharmaceuticals
NCT01437007 COMPLETED TKM 080301 for Primary or Secondary Liver Cancer
National Cancer Institute (NCI)
NCT01804530 TERMINATED Phase 1 Study of PLX7486 as Single Agent in Patients With Advanced Solid Tumors
Plexxikon
NCT02673736 TERMINATED A Study of PLX73086 in Advanced Solid Tumors and Locally Advanced or Refractory Tenosynovial Giant Cell Tumor
Plexxikon
NCT01151670 COMPLETED Pioglitazone Hydrochloride in Preventing Radiation-Induced Cognitive Dysfunction in Treating Patients With Brain Tumors
Wake Forest University Health Sciences
NCT01022853 COMPLETED Combination of BI6727 (Volasertib) and BIBF1120 in Solid Tumors
Boehringer Ingelheim
NCT02914327 WITHDRAWN Safety and Activity of SNX-5422 Plus Ibrutinib in CLL
Esanex Inc.
NCT01971476 COMPLETED Open Dose Escalating Trial to Determine the Maximum Tolerated Dose in Paediatric Patients With Advanced Cancers for Whom no Therapy is Known
Boehringer Ingelheim
NCT02063958 COMPLETED Safety and Pharmacology of SNX-5422 Plus Everolimus in Subjects With Neuroendocrine Tumors
Esanex Inc.
NCT01378377 TERMINATED Combination Trial of Pimasertib (MSC1936369B) With Temsirolimus
EMD Serono
NCT02780011 WITHDRAWN Alsertib (MLN8237) and Brentuximab Vedotin for Relapsed/Refractory CD30-Positive Lymphomas and Solid Malignancies
Eric Bernicker, MD
NCT02386111 TERMINATED A Study of Varlilumab (Anti-CD27) and Sunitinib in Patients With Metastatic Clear Cell Renal Cell Carcinoma
Celldex Therapeutics
NCT01458067 COMPLETED A Phase I/IIa, First Time in Human, Study of GSK2636771 in Subjects With Advanced Solid Tumors With Phosphatase and Tensin Homolog (PTEN) Deficiency
GlaxoSmithKline
NCT03111069 WITHDRAWN Study of Doxorubicin and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) and Intraoperative Brachytherapy for Unresectable or Refractory Pelvic and Abdominal Rhabdomyosarcoma and Undifferentiated Sarcomas in Children
M.D. Anderson Cancer Center
NCT01484015 COMPLETED Prolonged or Standard Infusion of Cefepime Hydrochloride in Treating Patients With Febrile Neutropenia
Wake Forest University Health Sciences
NCT02987504 TERMINATED Study of Samalizumab in Patients With Advanced Cancer
Alexion Pharmaceuticals, Inc.
NCT01800071 COMPLETED A Phase Ib Trial of MVA-EBNA1/LMP2 Vaccine in Nasopharyngeal Carcinoma
Cancer Research UK
NCT01705002 COMPLETED Intravenously Administered Pegylated Liposomal Mitomycin-C Lipid-based Prodrug (PROMITIL) in Cancer Patients With Solid Tumors.
Lipomedix Pharmaceuticals Inc.
NCT00678132 COMPLETED AZD2281 and Cisplatin Plus Gemcitabine to Treat Solid Tumor Cancers
National Cancer Institute (NCI)
NCT01246102 COMPLETED AT13387 in Adults With Refractory Solid Tumors
National Cancer Institute (NCI)
NCT02839694 WITHDRAWN Adjuvant Oral Decitabine and Tetrahydrouridine With or Without Celecoxib in People Undergoing Pulmonary Metastasectomy
National Cancer Institute (NCI)
NCT01120288 COMPLETED A Pilot Study of EZN-2968, an Antisense Oligonucleotide Inhibitor of HIF-1alpha, in Adults With Advanced Solid Tumors With Liver Metastases
National Cancer Institute (NCI)
NCT01259479 COMPLETED Satraplatin in Children and Young Adults With Refractory Solid Tumors Including Brain Tumors
National Cancer Institute (NCI)
NCT02166255 COMPLETED APN401 in Treating Patients With Melanoma, Kidney Cancer, Pancreatic Cancer, or Other Solid Tumors That Are Metastatic or Cannot Be Removed By Surgery
Wake Forest University Health Sciences
NCT00958724 COMPLETED Study Evaluating Neratinib In Combination With Vinorelbine In Subjects With Advanced Or Metastatic Solid Tumors
Puma Biotechnology, Inc.
NCT03082053 COMPLETED A Study of Varlitinib in Japanese Subjects With Advanced or Metastatic Solid Tumours
ASLAN Pharmaceuticals
NCT00816400 COMPLETED A Dose Escalation, Dose Expansion Study to Evaluate the Safety, Tolerability, and Antitumor Activity of MEDI-575, in Subjects With Advanced Tumors.
MedImmune LLC
NCT01690741 COMPLETED Phase 1 Trial of Intravenously Administered Nerofe™ in Subjects With Advanced Malignancies
Immune System Key Ltd
NCT02146313 COMPLETED A Study Evaluating the Safety and Pharmacokinetics of DMUC4064A in Participants With Platinum-Resistant Ovarian Cancer or Unresectable Pancreatic Cancer
Genentech, Inc.
NCT02439489 COMPLETED Study of the Combination of BKM120 and Cisplatin or Carboplatin in Patients With Advanced Solid Tumors
Fondazione Michelangelo
NCT03077477 WITHDRAWN Study of Orally-Administered AMXT 1501 Dicaprate in Normal Healthy Volunteers
Aminex Therapeutics, Inc.
NCT00878449 COMPLETED A Study Evaluating the Safety of ABT-263 in Combination With Etoposide/Cisplatin in Subjects With Cancer
AbbVie (prior sponsor, Abbott)
NCT02485119 COMPLETED Phase I Dose Escalation Study of BAY94-9343 Given by Intravenous Infusion Every 3 Weeks in Japanese Subjects With Advanced Malignancies
Bayer
NCT02065063 COMPLETED A Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics, and Anti-Cancer Activity of Trametinib in Combination With Palbociclib in Subjects With Solid Tumors
GlaxoSmithKline
NCT01705106 TERMINATED Capecitabine and Celecoxib in Patients With Solid Cancers That Have Been Previously Treated With Standard Therapies
University of Chicago
NCT02035527 COMPLETED Sorafenib Tosylate, Cisplatin, and Docetaxel in Treating Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
Ohio State University Comprehensive Cancer Center
NCT02057289 TERMINATED A Pharmacokinetic Study of Pediatric Micafungin Prophylaxis
Children's Hospital Medical Center, Cincinnati
NCT02760797 COMPLETED A Study of Emactuzumab and RO7009789 Administered in Combination in Participants With Advanced Solid Tumors
Hoffmann-La Roche
NCT00736372 COMPLETED A Trial of PX-12 in Patients With a Histologically or Cytologically Confirmed Diagnosis of Advanced or Metastatic Cancer
Cascadian Therapeutics Inc.
NCT00726583 COMPLETED Phase I Trial of Oral PX-866
Cascadian Therapeutics Inc.
NCT01978964 COMPLETED Phase 1b Maintenance Therapy Study of ONT-10 in Patients With Solid Tumors
Cascadian Therapeutics Inc.
NCT02323893 COMPLETED Study of Kinetics, Dosimetry & Safety of [18F]F-AraG, a Positron Emission Tomography Imaging Tracer in Healthy Humans
CellSight Technologies, Inc.
NCT00837928 COMPLETED Bendamustine and Radiation Therapy in Treating Patients With Brain Metastases Caused by Solid Tumors
John Grecula
NCT01556789 COMPLETED Phase 1 Study of ONT-10 in Patients With Solid Tumors
Cascadian Therapeutics Inc.
NCT02098967 COMPLETED A Study of the Safety and Pharmacokinetics of RO6839921, An MDM2 Antagonist, in Patients With Advanced Cancers, Including Acute Myeloid Leukemia.
Hoffmann-La Roche
NCT02284971 TERMINATED Pilot Study of SBRT and CDX-1127 in Prostate Cancer
James Larner, MD
NCT02690350 TERMINATED An Open Study Assessing the Safety and Tolerability of U3-1784
Daiichi Sankyo
NCT02036281 COMPLETED A Phase 1 Study of Substance P-Saporin in Terminal Cancer Patients With Intractable Pain
University of Texas Southwestern Medical Center
NCT02222363 TERMINATED Study of Safety and Tolerability of VLX600, an Iron Chelator, in Patients With Refractory Advanced Solid Tumors
Vivolux AB
NCT02210663 COMPLETED A Phase 1 Study of Single Agent Veliparib in Japanese Subjects With Advanced Solid Tumors
AbbVie
NCT02833506 WITHDRAWN Sirolimus and Vaccine Therapy in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Roswell Park Cancer Institute
NCT02275039 COMPLETED p53MVA Vaccine and Gemcitabine Hydrochloride in Treating Patients With Recurrent Ovarian Epithelial Cancer
City of Hope Medical Center
NCT02543645 TERMINATED A Study of Varlilumab and Atezolizumab in Patients With Advanced Cancer
Celldex Therapeutics
NCT03502395 COMPLETED Serum Opiorphin Level After Intraoperative Intravenous Lidocaine Infusion
Assiut University
NCT02592785 COMPLETED Phase I Dose Escalation Study of BAY 1163877 (Rogaratinib) in Japanese Subjects With Refractory, Locally Advanced or Metastatic Solid Tumors
Bayer
NCT01762280 COMPLETED A Phase I Study of Famitinib Malate in Patients With Solid Tumor
Jiangsu HengRui Medicine Co., Ltd.
NCT00784914 COMPLETED A Feasibility, Dose-Escalation Study Using Intracerebral Microdialysis to Assess the Neuropharmacodynamics of Temsirolimus in Patients With Primary or Metastatic Brain Tumors
City of Hope Medical Center
NCT00820768 WITHDRAWN A Trial of ABI-010 & ABI-007 in Patients With Advanced Non-Hematologic Malignancies
Celgene
NCT01875705 COMPLETED A Dose-Escalation Study of GDC-0994 in Patients With Locally Advanced or Metastatic Solid Tumors
Genentech, Inc.
NCT03448211 WITHDRAWN A Study of PTS for Patients With Solid Tumors
PTS International Inc.
NCT01440998 COMPLETED Dasatinib, Paclitaxel, and Carboplatin in Treating Patients With Stage III-IV or Recurrent Endometrial Cancer
National Cancer Institute (NCI)
NCT02558140 COMPLETED A Dose Escalation Study of RO6874813 in Participants With Locally Advanced or Metastatic Solid Tumors
Hoffmann-La Roche
NCT02192541 TERMINATED Ganetespib and Ziv-Aflibercept in Refractory Gastrointestinal Carcinomas, Non-Squamous Non-Small Cell Lung Carcinomas, Urothelial Carcinomas, and Sarcomas
National Cancer Institute (NCI)
NCT01526473 COMPLETED A Phase I Study To Evaluate The Antitumor Activity And Safety Of AVX901
H. Kim Lyerly
NCT02671955 TERMINATED A Study of Safety, Pharmacokinetics, Pharmacodynamics of JNJ-61610588 in Participants With Advanced Cancer
Janssen Research & Development, LLC
NCT01275612 WITHDRAWN Mesenchymal Stem Cells In Cisplatin-Induced Acute Renal Failure In Patients With Solid Organ Cancers
Mario Negri Institute for Pharmacological Research
NCT01520389 COMPLETED Safety Study of the Drug MM-151 in Patients With Advanced Solid Tumors Resisting Ordinary Treatment
Merrimack Pharmaceuticals
NCT00931931 COMPLETED HSV1716 in Patients With Non-Central Nervous System (Non-CNS) Solid Tumors
Timothy Cripe
NCT01400555 COMPLETED A Safety Study of Abiraterone Acetate Administered in Combination With Docetaxel in Patients With Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Cougar Biotechnology, Inc.
NCT02621268 COMPLETED Minimally Invasive Imagery With Indocyanine Green
University of Pennsylvania
NCT02280954 COMPLETED Indocyanine Green for Solid Tumors
University of Pennsylvania
NCT01470209 COMPLETED A Phase I Study of BKM120 and Everolimus in Advanced Solid Malignancies
Emory University
NCT01494688 COMPLETED A Study of RO5509554 as Monotherapy and in Combination With Paclitaxel in Participants With Advanced Solid Tumors
Hoffmann-La Roche
NCT01224730 COMPLETED A Food Effect and QTc Study of Perifosine in Patients With Advanced Malignancies
AEterna Zentaris
NCT01809210 COMPLETED Assess Safety & Efficacy of Selumetinib When Given in Combination With Standard First Line Treatment for Advanced Non-small Cell Lung Cancer
AstraZeneca
NCT02349139 TERMINATED Safety, Preliminary Efficacy and Pharmacokinetics of ASN001 in Metastatic Castrate Resistant Prostate Cancer
Asana BioSciences
NCT02004106 COMPLETED A Study to Evaluate Safety, Pharmacokinetics, and Efficacy of RO6895882 in Participants With Advanced and/or Metastatic Solid Tumors
Hoffmann-La Roche
NCT01744054 TERMINATED Microsphere Localization Using PET/MRI or PET/CT in Patients Following Radioembolization
Washington University School of Medicine
NCT00790816 COMPLETED Continuation Study of Lapatinib Monotherapy or Lapatinib in Combination With Other Anti-cancer Agents
Novartis Pharmaceuticals
NCT01691807 COMPLETED Drug-drug Interaction Study of Ofatumumab With Bendamustine in Subjects With Indolent B-cell Non-Hodgkin's Lymphoma
Novartis Pharmaceuticals
NCT02243917 TERMINATED A Phase 1 Study Evaluating CB-5083 in Subjects With Advanced Solid Tumors
Cleave Biosciences, Inc.
NCT03168035 COMPLETED Study of NC-4016 in Patients With Advanced Solid Tumors or Lymphoma
NanoCarrier Co., Ltd.
NCT01505153 COMPLETED Phase I Intratumoral Pbi-shRNA STMN1 LP in Advanced and/or Metastatic Cancer
Gradalis, Inc.
NCT01285037 COMPLETED A Study of LY2801653 in Advanced Cancer
Eli Lilly and Company
NCT02122146 TERMINATED A Study Of PF-06664178 In Patients With Advanced Solid Tumors
Pfizer
NCT01767623 COMPLETED A Study of The Impact of Severe Hepatic Impairment on the Pharmacokinetics and Safety of Vemurafenib in BRAF V600 Mutation-Positive Cancer Participants
Hoffmann-La Roche
NCT01822756 TERMINATED An Open-Label Study of Ruxolitinib Given With Chemotherapy in Patients With Advanced Solid Tumors
Incyte Corporation
NCT01702285 TERMINATED Phase I Study to Assess the Safety, Tolerability, and Pharmacokinetics of Orally Administered CUDC-101 in Cancer Patients
Curis, Inc.
NCT01219777 COMPLETED Neoadjuvant Chemotherapy IV Carboplatin With Weekly Paclitaxel \Bevacizumab for Primary Ovarian
Ritu Salani
NCT03422874 WITHDRAWN Dose Escalation Study of Nelfinavir Plus MLN9708 in Patients With Advanced Solid Tumors or Lymphoma
Dartmouth-Hitchcock Medical Center
NCT01335893 COMPLETED Intraoperative Imaging of Thoracic Malignancies With Indocyanine Green
University of Pennsylvania
NCT01704963 COMPLETED A Study to Evaluate the Bruton's Tyrosine Kinase (Btk) Inhibitor PCI-32765 in Patients With Recurrent Mature B-Cell Neoplasms
Janssen Pharmaceutical K.K.
NCT02228811 TERMINATED A Study of DCC-2701 in Participants With Advanced Solid Tumors
Deciphera Pharmaceuticals, LLC
NCT01903083 COMPLETED Chemoimmunotherapy and Radiation in Pancreatic Cancer
Providence Health & Services
NCT01728311 COMPLETED Open Label Study of BAY1082439 in Patients With Advanced Cancer
Bayer
NCT02164838 COMPLETED VEGF Receptor Tyrosine Kinase Inhibitor Axitinib in Children With Recurrent or Refractory Solid Tumors
Children's Oncology Group
NCT01519817 COMPLETED Cancer Vaccine Targeting Brachyury Protein in Tumors
National Cancer Institute (NCI)
NCT02318394 COMPLETED A Phase 1 Study of MEDI0562 in Adult Subjects With Selected Advanced Solid Tumors
MedImmune LLC
NCT02168777 TERMINATED Refametinib (BAY86-9766) in Combination With Regorafenib (Stivarga, BAY73-4506) in Patients With Advanced or Metastatic Cancer
Bayer
NCT02363855 COMPLETED Phase 1 Dose Escalation Study of BAY 1841788 in Japanese Metastatic Castration-resistant Prostate Cancer (mCRPC) Subjects
Bayer
NCT02359058 COMPLETED A Study of Ramucirumab Combination Therapy in Japanese Participants Who Have Advanced Stomach Cancer
Eli Lilly and Company
NCT00825201 COMPLETED Intraperitoneal Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced Cancer of the Peritoneal Cavity
City of Hope Medical Center
NCT03205891 WITHDRAWN Study of Brentuximab Vedotin Plus TAK228 for Relapsed/Refractory Classical Hodgkin Lymphoma, Anaplastic Large Cell Lymphoma and Other CD30+Peripheral T-Cell Lymphomas
M.D. Anderson Cancer Center
NCT01929941 TERMINATED An Open-Label Study of a Novel JAK-inhibitor, INCB047986, Given in Patients With Advanced Malignancies
Incyte Corporation
NCT02296879 COMPLETED A Multicenter, Open Label, Phase I Dose Escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Intravenous SAIT301 in Subjects With Advanced c-MET Positive (+) Solid Tumors Followed by Expansion in Selected Tumor Types
Young Suk Park
NCT02014337 COMPLETED Mifepristone and Eribulin in Patients With Metastatic Triple Negative Breast Cancer or Other Specified Solid Tumors
Corcept Therapeutics
NCT01813474 COMPLETED Investigate the Safety and Tolerability of Olaparib Tablet in Japanese Patients With Advanced Solid Malignancies
AstraZeneca
NCT00908167 COMPLETED Sorafenib in Combination With Cytarabine and Clofarabine in Patients With Refractory or Relapsed Hematologic Malignancies
St. Jude Children's Research Hospital
NCT01677559 COMPLETED Combining MLN8237 With Nab-Paclitaxel in Patients With Advanced Solid Malignancies
Washington University School of Medicine
NCT00807755 TERMINATED Everolimus, Carboplatin, and Etoposide in Treating Patients With Small Cell Lung Cancer or Other Advanced Solid Tumors
University of California, Davis
NCT01336842 COMPLETED Study of Cisplatin and Pemetrexed in Combination With Panobinostat in Solid Tumors
University of California, Davis
NCT02194049 COMPLETED Cisplatin, Etoposide and PI3K Inhibitor BKM120 in Treating Patients With Advanced Solid Tumors or Small Cell Lung Cancer
University of California, Davis
NCT01987362 COMPLETED A Two Part Study of RO6870810. Dose-Escalation Study in Participants With Advanced Solid Tumors and Expansion Study in Participants With Selected Malignancies
Hoffmann-La Roche
NCT01339650 COMPLETED Study of ABT-767 in Subjects With Breast Cancer 1 and Breast Cancer 2 (BRCA 1 and BRCA 2) Mutations and Solid Tumors or High Grade Serous Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
AbbVie (prior sponsor, Abbott)
NCT01012362 TERMINATED Study of Pazopanib and Ixabepilone in Patients With Solid Tumors
Masonic Cancer Center, University of Minnesota
NCT00921869 COMPLETED A Study of E7050 Administered Orally to Patients With Advanced Solid Tumors
Eisai Co., Ltd.
NCT02164097 TERMINATED ODSH + ICE Chemotherapy in Pediatric Solid Tumors
New York Medical College
NCT02828930 COMPLETED A Study to Determine the Excretion Balance, Pharmacokinetics, Metabolism and Absolute Oral Bioavailability of a Single Oral Dose of [14C]-Labeled Idasanutlin and an Intravenous Tracer Dose of [13C]-Labeled Idasanutlin in a Single Cohort of Participants With Solid Tumors (Malignancies)
Hoffmann-La Roche
NCT01404390 COMPLETED Japanese BAY80-6946 Monotherapy Phase I Study
Bayer
NCT02404480 COMPLETED PTC596 in Patients With Advanced Solid Tumors
PTC Therapeutics
NCT00610493 COMPLETED Bevacizumab and Temsirolimus in Patients With Advanced Malignancy
M.D. Anderson Cancer Center
NCT01200316 COMPLETED Rocking Motion: Physiologic Effect on the Surgical Stress Response
M.D. Anderson Cancer Center
NCT01072266 COMPLETED A Dose-escalation Study in Subjects With Advanced Malignancies
Incyte Corporation
NCT00649207 COMPLETED A Phase I Study of ABT-888 in Combination With Conventional Whole Brain Radiation Therapy (WBRT) in Cancer Patients With Brain Metastases
AbbVie (prior sponsor, Abbott)
NCT01413893 COMPLETED An Extension Study of Linifanib (ABT-869) in Subjects With Advanced or Metastatic Solid Tumors
AbbVie
NCT01121133 COMPLETED A Study to Assess the Effect of Rifampin on the Metabolism of Navitoclax
AbbVie
NCT00982566 COMPLETED Assess the Oral Bioavailability of a New ABT-263 Formulation in Subjects With Cancer
AbbVie
NCT01472016 COMPLETED Study of ABT-700 in Subjects With Advanced Solid Tumors
AbbVie (prior sponsor, Abbott)
NCT00733187 COMPLETED Pharmacokinetic Study To Evaluate Effect of Food and Diurnal Variation on ABT-869
AbbVie (prior sponsor, Abbott)
NCT00891605 COMPLETED Safety Study of ABT-263 in Combination With Paclitaxel in Subjects With Solid Tumors
AbbVie
NCT00718380 COMPLETED A Phase 1 Study of ABT-869 in Subjects With Solid Tumors
AbbVie
NCT01199224 COMPLETED To Determine the Food Effect and Bioavailability of Three Formulations of Veliparib in Subjects With Solid Tumors
AbbVie
NCT00887757 COMPLETED Safety Study of ABT-263 in Combination With Gemzar (Gemcitabine) in Subjects With Solid Tumors
AbbVie
NCT01255657 COMPLETED A Study of ABT-806 in Subjects With Advanced Solid Tumor Types
AbbVie (prior sponsor, Abbott)
NCT01009073 COMPLETED A Study Evaluating ABT-263 With Erlotinib, ABT-263 With Irinotecan, and ABT-263 Monotherapy in Cancer Subjects
AbbVie (prior sponsor, Abbott)
NCT02009631 COMPLETED A Study to Evaluate the Effects of Veliparib on Heart Rhythms in Patients With Solid Tumors
AbbVie
NCT01617928 COMPLETED A Study of Veliparib in Combination With Carboplatin and Paclitaxel in Japanese Subjects With Solid Tumors
AbbVie (prior sponsor, Abbott)
NCT02593708 TERMINATED Phase1 of Neratinib+Trastuzumab, Pertuzumab, Paclitaxel in Patients With Advanced Solid Tumors/HER2+
Michelle Melisko
NCT00650910 COMPLETED Study To Examine The Effects Of Lapatinib On The Pharmacokinetics Of Digoxin In Subjects w/ ErbB2 Positive Breast Cancer
GlaxoSmithKline
NCT00849329 COMPLETED A Study to Examine the Effects of Esomeprazole on the Pharmacokinetics of Orally Administered Lapatinib in Subjects With Metastatic ErbB2 Positive Breast Cancer
GlaxoSmithKline
NCT01231568 COMPLETED An Open Label Study to Examine the Effects of a High-Fat Meal and Particle Size on the Pharmacokinetics of Orally Administered GSK2118436 in Subjects With BRAF Mutation Positive Tumor
GlaxoSmithKline
NCT01954043 COMPLETED A Pharmacokinetics (PK) Study of the Effects Rabeprazole and Rifampin on Dabrafenib in Subjects With BRAF V600 Mutation Positive Tumors
GlaxoSmithKline
NCT01437254 COMPLETED To Compare Safety and the General Imaging Pattern of Cyclotron Produced Technetium vs. Generator Produced Technetium in Patients With Thyroid Cancer
AHS Cancer Control Alberta
NCT01192165 COMPLETED Safety and Tolerability Study of GSK1120212, a MEK Inhibitor, in Combination With Docetaxel, Erlotinib, Pemetrexed, Pemetrexed + Carboplatin, Pemetrexed + Cisplatin, or Nab-Paclitaxel
GlaxoSmithKline
NCT01725100 COMPLETED A Study to Determine the Relative Bioavailability of the MEK Inhibitor, Trametinib, in Subjects With Solid Tumor Malignancies
GlaxoSmithKline
NCT01387204 COMPLETED Study to Investigate the Absorption, Distribution, Metabolism and Elimination of [14C]GSK1120212
GlaxoSmithKline
NCT00996762 COMPLETED A Study in Cancer Patients to Evaluate the Bioequivalence of Alternative Formulations of Lapatinib
GlaxoSmithKline
NCT02040480 COMPLETED Bioavailability and Food Effect Study of Gelatin Formulation and Immediate Release Tablet Formulation of Afuresertib
GlaxoSmithKline
NCT00880321 COMPLETED A Phase I Study to Investigate the Safety, Pharmacokinetics, and Pharmacodynamics of GSK2118436 in Subjects With Solid Tumors
GlaxoSmithKline
NCT00821054 COMPLETED A Study to Examine the Effects of Low and High-fat Meals on Orally Administered Lapatinib in Metastatic ErbB2 Positive Breast Cancer Patients
GlaxoSmithKline
NCT00920257 COMPLETED A Phase I, Open-Label, First-Time-In-Human Study of the Oral AKT Inhibitor GSK2141795
GlaxoSmithKline
NCT01371487 COMPLETED GSK1120212 Food-effect Study
GlaxoSmithKline
NCT01340846 COMPLETED A Pharmacokinetics Study of the Effects of GSK2118436 on Warfarin, the Effects of Ketoconazole and Gemfibrozil on GSK2118436, and the Effects of Repeat Doses of GSK2118436 in Subjects With BRAF Mutant Solid Tumors
GlaxoSmithKline
NCT01138085 COMPLETED Safety, Pharmacokinetics (PK) of AKT and MEK Combination
GlaxoSmithKline
NCT01290354 COMPLETED Exploratory Lapatinib (Positron Emission Tomography) PET Study in Subjects With Breast Cancer
GlaxoSmithKline
NCT00722293 COMPLETED A Phase I, Open-label, Study of Pazopanib in Combination With Epirubicin or Doxorubicin for Advanced Solid Tumors
GlaxoSmithKline
NCT01827644 COMPLETED Bioavailability and Food Effect of the Original Gelatin Formulation and Two New Formulations of Afuresertib in Normal Healthy Volunteers
GlaxoSmithKline
NCT01738451 COMPLETED A Study to Evaluate the Effect of Repeat Oral Dosing of GSK2118436 on Cardiac Repolarization in Subjects With V600 BRAF Mutation-Positive Tumors
GlaxoSmithKline
NCT01658553 COMPLETED A Study to Look at the Electrical Activity of the Heart in Subjects With Solid Tumor Cancers, Before and After Receiving the Study Treatment, GSK1120212
GlaxoSmithKline
NCT01416337 COMPLETED Absolute Bioavialability of GSK1120212
GlaxoSmithKline
NCT01340833 COMPLETED Determination of the Absolute Bioavailability of GSK2118436 Following a Single Oral Dose Co-Administered With an Intravenous Radiolabelled Microtracer of GSK2118436 in Subjects With BRAF Mutant Solid Tumors
GlaxoSmithKline
NCT01262963 COMPLETED An Absorption, Distribution, Metabolism and Excretion (ADME) Study of Single Oral Dose [14C] GSK2118436 in Subjects With BRAF Mutant Solid Tumors
GlaxoSmithKline
NCT01476137 COMPLETED A Study of the Safety and Activity of the MEK Inhibitor Given Together With the AKT Inhibitor to Patients With Multiple Myeloma or Solid Tumor Cancers
GlaxoSmithKline
NCT01582997 COMPLETED A Phase I Study to Investigate the Safety, Tolerability and Pharmacokinetic Profile of of GSK2118436 in Japanese Subjects With BRAF Mutation Positive Solid Tumors
GlaxoSmithKline
NCT01647659 COMPLETED Relative Bioavailibilty for Pediatric Powder for Suspension (PfOS) Formulation
GlaxoSmithKline
NCT00955773 COMPLETED A Study of the GSK MEK Inhibitor GSK1120212 and Everolimus in Cancer Subjects
GlaxoSmithKline
NCT01331941 COMPLETED A Pharmacokinetic Study of AMG 386 in Cancer Subjects With Normal and Impaired Renal Function
Amgen
NCT01123005 TERMINATED Imaging and Biomarkers of Hypoxia in Solid Tumors
Stanford University
NCT01898715 COMPLETED Phase 1 Study of ATR-101 in Subjects With Advanced Adrenocortical Carcinoma
Millendo Therapeutics, Inc.
NCT03247283 COMPLETED Pharmacokinetics and Metabolism Study in Healthy Male Participants
Bristol-Myers Squibb
NCT01380756 COMPLETED Study Evaluating Orally Administered AMG 900 in Adult Subjects With Acute Myeloid Leukemia
Amgen
NCT01721525 COMPLETED Induction Chemotherapy With Afatinib, Ribavirin, and Weekly Carboplatin/Paclitaxel for Stage IVA/IVB HPV Associated Oropharynx Squamous Cell Cancer (OPSCC)
Memorial Sloan Kettering Cancer Center
NCT01186484 COMPLETED Phase 1 Study of Abiraterone Acetate in Castration-resistant Prostate Cancer
Janssen Pharmaceutical K.K.
NCT01473095 COMPLETED Phase 1 Dose Escalation Study of ARQ 092 in Adult Subjects With Advanced Solid Tumors and Recurrent Malignant Lymphoma
ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA)
NCT01938638 COMPLETED Open Label Phase I Dose Escalation Study With BAY1143572 in Patients With Advanced Cancer
Bayer
NCT01159522 COMPLETED A Dose Escalation Study of SCB01A in Subjects With Advanced Solid Tumors Who Have Failed Standard Therapy
SynCore Biotechnology Co., Ltd.
NCT02303366 COMPLETED Pilot Study of Stereotactic Ablation for Oligometastatic Breast Neoplasia in Combination With the Anti-PD-1 Antibody MK-3475
Peter MacCallum Cancer Centre, Australia
NCT01281488 COMPLETED Fluorescence Imaging in Finding Tumors in Patients With Kidney Tumors
City of Hope Medical Center
NCT01411410 COMPLETED Phase I Study of PI3(Phosphoinositol 3)-Kinase Inhibitor BAY80-6946 With Paclitaxel in Patients With Advanced Cancer
Bayer
NCT03007771 WITHDRAWN Magnetic Resonance-guided High-Intensity Focused Ultrasound (MR-HIFU) Used for Mild Hyperthermia
Washington University School of Medicine
NCT02151357 TERMINATED Safety, Tolerability and Pharmacokinetics of DCBCI0901 in Patients With Advanced Solid Tumor
Standard Chem. & Pharm. Co., Ltd.
NCT00962611 COMPLETED BAY80-6946 Open Label, Phase I Study in Patients With Advanced Cancer
Bayer
NCT01460537 COMPLETED Phase 1 Study of PI3 (Phosphatidylinositol-3)-Kinase Inhibitor Copanlisib With Gemcitabine or Cisplatin Plus Gemcitabine in Patients With Advanced Cancer
Bayer
NCT01581541 TERMINATED PU-H71 in Patients With Solid Tumors and Low-Grade Non-Hodgkin's Lymphoma That Have Not Responded to Standard Treatment
National Cancer Institute (NCI)
NCT01449058 COMPLETED A Phase Ib Study of MEK162 Plus BYL719 in Adult Patients With Selected Advanced Solid Tumors
Array BioPharma
NCT01671592 COMPLETED Safety of Labeled Dendritic Cell (DC) Vaccines and Feasibility of Tracking by Magnetic Resonance Imaging (MRI)
Pawel Kalinski
NCT02658708 COMPLETED Bright Light on Fatigue in Women Being Treated for Breast Cancer
Washington University School of Medicine
NCT00572078 COMPLETED Sorafenib and Bevacizumab in Combination With Paclitaxel in Patients With Solid Tumors
Safi Shahda
NCT03283046 WITHDRAWN Study of Lenalidomide/Dexamethasone With Nivolumab and Ipilimumab in Patients With Newly Diagnosed Multiple Myeloma
M.D. Anderson Cancer Center
NCT02286219 COMPLETED Phase 1, Multiple Ascending Dose Study of Anti-HER2 FCAB FS102 in HER2 Positive Solid Tumors (Anti HER2 Fcab)
Bristol-Myers Squibb
NCT01727076 COMPLETED Recombinant Interleukin-15 in Treating Patients With Advanced Melanoma, Kidney Cancer, Non-small Cell Lung Cancer, or Squamous Cell Head and Neck Cancer
National Cancer Institute (NCI)
NCT01881217 COMPLETED First-in-man Dose Escalation Study of BAY1179470 in Patients With Advanced, Refractory Solid Tumors
Bayer
NCT01485042 COMPLETED Dose Escalation Study of Pazopanib Plus TH-302
Herbert Hurwitz, MD
NCT02745756 WITHDRAWN A Combined Cell Therapy Approach to the Treatment of Neuroblastoma
H. Lee Moffitt Cancer Center and Research Institute
NCT00575952 COMPLETED Intraperitoneal Paclitaxel, Doxorubicin Hydrochloride, and Cisplatin in Treating Patients With Stage III-IV Endometrial Cancer
Gynecologic Oncology Group
NCT01955473 COMPLETED Japanese Phase 1 Trial of Sym004 in Solid Tumors
Merck KGaA, Darmstadt, Germany
NCT01668017 TERMINATED A Multicentre, Open Label, Phase 1 Trial in Japan of the Mitogen Activated Protein Extracellular Signal Regulated Kinase (MEK) Inhibitor Pimasertib Given Orally to Subjects With Solid Tumors as Monotherapy
Merck KGaA, Darmstadt, Germany
NCT01508104 TERMINATED Safety Study of BEZ235 With Everolimus in Subjects With Advanced Solid Tumors
University of Cincinnati
NCT00624936 COMPLETED Azacytidine and Bortezomib in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndromes
Ohio State University Comprehensive Cancer Center
NCT01719926 COMPLETED Phase I Platinum Based Chemotherapy Plus Indomethacin
UMC Utrecht
NCT01302405 TERMINATED Safety and Efficacy Study of PRI-724 in Subjects With Advanced Solid Tumors
Prism Pharma Co., Ltd.
NCT01992874 COMPLETED Relative Bioavailability of Pimasertib in Cancer Patients
EMD Serono
NCT01713036 COMPLETED Oral Bioavailability and Mass Balance Trial With Pimasertib
Merck KGaA, Darmstadt, Germany
NCT03246009 COMPLETED Fusion Protein rHSA/GCSFclinical Study on Breast Cancer Patients
Tianjin SinoBiotech Ltd.
NCT01383538 COMPLETED FOLFIRINOX Plus IPI-926 for Advanced Pancreatic Adenocarcinoma
Andrew Ko
NCT01975116 COMPLETED p28 in Treating Younger Patients With Recurrent or Progressive Central Nervous System Tumors
Pediatric Brain Tumor Consortium
NCT01610479 COMPLETED A Study of TAS-114 in Combination With S-1 in Patients With Advanced Solid Tumors
Taiho Pharmaceutical Co., Ltd.
NCT00706576 COMPLETED Treatment of Unresectable Hepatocellular Cancer With Opioid Growth Factor
University of Missouri-Columbia
NCT00728468 COMPLETED A Study To Test The Impact Of PF- 00299804 On How The Body Handles Dextromethorphan In Cancer Patients
Pfizer
NCT00776867 COMPLETED Study of Single Agent Perifosine for Recurrent Pediatric Solid Tumors
Memorial Sloan Kettering Cancer Center
NCT01143753 COMPLETED A Study of RO5212054 (PLX3603) in Participants With BRAF V600-Mutated Advanced Solid Tumors
Hoffmann-La Roche
NCT02674555 WITHDRAWN A Study to Investigate the Absorption, Metabolism and Excretion of [14C]ASP8273 in Subjects With Solid Tumors
Astellas Pharma Global Development, Inc.
NCT01849744 TERMINATED Phase I Dose Escalation Study of VS-4718 in Subjects With Metastatic Non-Hematologic Malignancies
Verastem, Inc.
NCT01892046 COMPLETED Safety and Pharmacology of SNX-5422 Plus Carboplatin and Paclitaxel in Subjects With Solid Tumors
Esanex Inc.
NCT02082665 COMPLETED Effects of Dabrafenib on the Single Dose Pharmacokinetics (PK) of Rosuvastatin and Midazolam
GlaxoSmithKline
NCT02014909 COMPLETED A Phase 1 Study to Evaluate the Safety and Pharmacokinetics of KTN3379 in Adult Subjects With Advanced Tumors
Celldex Therapeutics
NCT00659178 COMPLETED Combination Study Of SB-485232 (Interleukin 18) And Doxil For Advanced Stage Epithelial Ovarian Cancer
GlaxoSmithKline
NCT00853528 COMPLETED Stereotactic Radiosurgery in Treating Patients With Spinal Metastases
Boston Medical Center
NCT01677780 COMPLETED An Extension Study of RO5045337 in Participants Participating in Previous Roche-sponsored Cancer Studies
Hoffmann-La Roche
NCT01682473 COMPLETED A Study of ZSTK474 in Japanese Patients With Advanced Solid Malignancies
Zenyaku Kogyo Co., Ltd.
NCT00987766 COMPLETED Gemcitabine Hydrochloride, Oxaliplatin, and Erlotinib Hydrochloride in Treating Patients With Advanced Biliary Tract Cancer, Pancreatic Cancer, Duodenal Cancer, or Ampullary Cancer
Vanderbilt-Ingram Cancer Center
NCT02428036 COMPLETED A Study of TBI-1401(HF10) in Patients With Solid Tumors With Superficial Lesions
Takara Bio Inc.
NCT01236586 WITHDRAWN RO4929097 in Children With Relapsed/Refractory Solid or CNS Tumors, Lymphoma, or T-Cell Leukemia
National Cancer Institute (NCI)
NCT00644072 COMPLETED SNX-5422 to Treat Solid Tumor Cancers and Lymphomas
National Cancer Institute (NCI)
NCT01419548 WITHDRAWN ABT-888, Carboplatin, and Paclitaxel for Cancer With Liver or Kidney Problems
National Cancer Institute (NCI)
NCT01182883 WITHDRAWN A Phase I Study of IMC-A12 in Combination With Temsirolimus in Pediatric Patients With Recurrent or Refractory Solid Tumors
National Cancer Institute (NCI)
NCT02412462 COMPLETED Phase I Dose Escalation Study of AB-16B5 in Subjects With an Advanced Solid Malignancy
Alethia Biotherapeutics
NCT02915172 WITHDRAWN Lenvatinib and Capecitabine in Patients With Advanced Malignancies
M.D. Anderson Cancer Center
NCT01168011 COMPLETED Safety, Pharmacokinetics and Clinical Activity of Oral Rigosertib in Solid Tumors
Traws Pharma, Inc.
NCT01165905 COMPLETED Safety of 24-hour Infusion of ON 01910.Na in Combination With Gemcitabine in Advanced Solid Tumors
Traws Pharma, Inc.
NCT00861783 COMPLETED Safety of ON 01910.Na and Irinotecan or ON 01910.Na and Oxaliplatin in Patients With Hepatoma
Traws Pharma, Inc.
NCT02107235 COMPLETED Platinum-based Chemoradiotherapy and Rigosertib in Head and Neck Cancer
Traws Pharma, Inc.
NCT01125891 COMPLETED Dose Escalation Study of Gemcitabine and ON 01910.Na in Solid Tumors
Traws Pharma, Inc.
NCT00861328 COMPLETED Safety Study of ON 01910.Na in Combination With Irinotecan or Oxaliplatin
Traws Pharma, Inc.
NCT02020577 COMPLETED Trial of Afatinib (BIBW 2992) + Cetuximab in Advanced Solid Tumours
Boehringer Ingelheim
NCT01670175 COMPLETED Sirolimus With Cyclophosphamide and Topotecan for Pediatric/Adolescent Relapsed and Refractory Solid Tumors
University of California, San Francisco
NCT02052492 COMPLETED Safety Study of EF-022 ( Modified Vitamin D Binding Protein Macrophage Activator) in Subjects With Advanced Solid Tumors
Efranat Ltd.
NCT02578316 COMPLETED A Study to Determine the Metabolism and Elimination of 14C-E7080 in Patients With Advanced Solid Tumors or Lymphomas, Who Are Unsuitable For, or Have Failed, Existing Therapies.
Eisai Inc.
NCT01179295 COMPLETED Japanese BAY86-9766 Monotherapy Phase I Study
Bayer
NCT01339871 COMPLETED Study of Pazopanib and Vorinostat in Patients With Advanced Malignancies
M.D. Anderson Cancer Center
NCT00920803 COMPLETED A Clinical Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of SRT501 in Subjects With Colorectal Cancer and Hepatic Metastases
Sirtris, a GSK Company
NCT00996671 COMPLETED Phase I Study to Evaluate Safety, Pharmacokinetics and Pharmacodynamics of GSK2256098 in Healthy Volunteers
GlaxoSmithKline
NCT01910545 COMPLETED Phase 1 Study of OTS167 in Patients With Solid Tumors
OncoTherapy Science, Inc.
NCT02429804 TERMINATED NaF/FDG PET/MRI in Measuring Response to Radium Ra 223 Dichloride in Patients With Metastatic Hormone-Resistant Prostate Cancer
Stanford University
NCT00513474 COMPLETED Rasburicase in Preventing Graft-Versus-Host Disease in Patients With Hematologic Cancer or Other Disease Undergoing Donor Stem Cell Transplant
Massachusetts General Hospital
NCT00654160 COMPLETED Irinotecan, Fluorouracil, and Leucovorin in Treating Patients With Advanced Gastrointestinal Cancer
Mayo Clinic
NCT01415297 COMPLETED Dose Escalation Study of NKP-1339 to Treat Advanced Solid Tumors
Niiki Pharma Inc.
NCT00670553 COMPLETED A Phase I Study of LBH589 (Panobinostat) in Combination With External Beam Radiotherapy for the Treatment of Prostate Cancer, Esophageal Cancer and Head and Neck Cancer
Novartis Pharmaceuticals
NCT01138033 COMPLETED Study of a Focal Adhesion Kinase Inhibitor in Subjects With Solid Tumors
GlaxoSmithKline
NCT01442870 COMPLETED Evaluation of Clinical Safety of Combining Metformin With Anticancer Chemotherapy
Tufts Medical Center
NCT01248858 TERMINATED Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of GSK2126458 and GSK1120212 Combination Therapy in Subjects With Advanced Solid Tumors.
GlaxoSmithKline
NCT01453387 TERMINATED MSC2015103B in Solid Tumors
EMD Serono
NCT00610948 COMPLETED Everolimus, Fluorouracil, Leucovorin, Panitumumab, and Oxaliplatin in Treating Patients With Tumors That Did Not Respond to Treatment
UNC Lineberger Comprehensive Cancer Center
NCT01577745 COMPLETED A Phase 1 Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of MEDI0639 in Advanced Solid Tumors
MedImmune LLC
NCT01129349 COMPLETED Phase 1 Study of Oprozomib Administered Orally in Patients With Advanced Refractory or Recurrent Solid Tumors
Amgen
NCT01949545 COMPLETED Study of the Pharmacokinetics and Safety of Carfilzomib in Patients With Advanced Malignancies and Hepatic Impairment
Amgen
NCT02274610 COMPLETED Pharmacokinetic Study of Docetaxel-PNP and Taxotere to Treat Patient With Advanced Solid Cancer
Samyang Biopharmaceuticals Corporation
NCT01494012 TERMINATED Phase I Stereotactic Body Radiation for Metastatic or Recurrent Platinum-Resistant Ovarian Cancer
Stanford University
NCT01635712 COMPLETED Safety and Pharmacology Study of SNX-5422 in Subjects With Refractory Hematological Malignancies
Esanex Inc.
NCT01571024 COMPLETED BKM120 + mFOLFOX6 in Advanced Solid Tumors With Expansion Cohort Pancreatic Cancer
UNC Lineberger Comprehensive Cancer Center
NCT00937417 WITHDRAWN S0716 Vandetanib and Docetaxel in Treating Patients With Advanced Solid Tumors
SWOG Cancer Research Network
NCT01416038 COMPLETED Phase 1 Study of a Cancer Vaccine to Treat Patients With Advanced Stage Ovarian, Fallopian or Peritoneal Cancer
ImmunoVaccine Technologies, Inc. (IMV Inc.)
NCT00769093 TERMINATED Assessing Dynamic Magnetic Resonance (MR) Imaging in Patients With Recurrent High Grade Glioma Receiving Chemotherapy
OHSU Knight Cancer Institute
NCT01049880 COMPLETED A Research Trial of High Dose Vitamin C and Chemotherapy for Metastatic Pancreatic Cancer
Joseph J. Cullen
NCT02055066 COMPLETED A Phase 1b Study of ARGX-111 in Patients With Advanced Cancer.
argenx
NCT01471210 COMPLETED Safety, Tolerability, Pharmacokinetics, and Immunoregulatory Study of Urelumab (BMS-663513) in Subjects With Advanced and/or Metastatic Solid Tumors and Relapsed/Refractory B-cell Non-Hodgkin's Lymphoma
Bristol-Myers Squibb
NCT01420146 COMPLETED Pilot Imaging Study With 89Zr-Trastuzumab in HER2-positive Metastatic Breast Cancer Patients
Jules Bordet Institute
NCT03117101 COMPLETED Study of the AL3810 in the Treatment of Advanced Solid Tumor
Haihe Biopharma Co., Ltd.
NCT01520220 COMPLETED Study of LY2784544 Testing Alternative Dosing in Participants With Myeloproliferative Neoplasms
Eli Lilly and Company
NCT01359696 COMPLETED A Study Evaluating the Safety, Tolerability, and Pharmacokinetics of GDC-0425 Administered With and Without Gemcitabine in Patients With Refractory Solid Tumors or Lymphoma
Genentech, Inc.
NCT01940133 COMPLETED A Study to Investigate Safety, Pharmacokinetics (PK) and Pharmacodynamics (PD) of PQR309
PIQUR Therapeutics AG
NCT02240212 COMPLETED Study of Afuresertib Combined With Paclitaxel in Gastric Cancer
Novartis Pharmaceuticals
NCT01957995 COMPLETED Nanosomal Docetaxel Lipid Suspension in Treating Patients With Advanced Solid Tumors
University of Southern California
NCT02040558 TERMINATED Trial to Study the Safety of Intravenous MNK-010 in Advanced Solid Tumors
Mallinckrodt
NCT00731276 COMPLETED Irinotecan in Treating Asian Patients With Solid Tumors
National Cancer Centre, Singapore
NCT01297452 COMPLETED BKM120 + Carboplatin + Paclitaxel for Patients With Advanced Solid Tumors
Memorial Sloan Kettering Cancer Center
NCT01248949 COMPLETED A Study to Evaluate the Safety and Antitumor Activity in Subjects With Advanced Solid Tumors
MedImmune LLC
NCT02812056 WITHDRAWN Alisertib and TAK-228 in Participants With Human Papilloma Virus (HPV) Associated Malignancies
M.D. Anderson Cancer Center
NCT02379741 COMPLETED ADC-1013 First-in-Human Study
Alligator Bioscience AB
NCT00878904 COMPLETED Panobinostat and Epirubicin in Treating Patients With Metastatic Malignant Solid Tumors
University of California, San Francisco
NCT01537744 COMPLETED A Trial of Oral 5-azacitidine in Combination With Romidepsin in Advanced Solid Tumors, With an Expansion Cohort in Virally Mediated Cancers and Liposarcoma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT00662636 COMPLETED Dasatinib and Lapatinib Ditolsylate in Treating Patients With Advanced Solid Tumors That Cannot Be Removed By Surgery
Mayo Clinic
NCT01155791 TERMINATED Phase I Sodium Selenite in Combination With Docetaxel in Castration-resistant Prostate Cancer
Sandy Srinivas
NCT01943188 TERMINATED Stereotactic Body Radiation Therapy and T-Cell Infusion in Treating Patients With Metastatic Kidney Cancer
Stanford University
NCT02031731 COMPLETED The Pharmacokinetics and Safety of Onartuzumab (MetMAb) in Chinese Patients With Locally Advanced or Metastatic Solid Tumors
Hoffmann-La Roche
NCT01248273 COMPLETED Unimolecular Pentavalent (Globo-H-GM2-sTn-TF-Tn) Immunization of Patients With Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer in First Remission
Memorial Sloan Kettering Cancer Center
NCT01049841 COMPLETED Perifosine With Temsirolimus for Recurrent Pediatric Solid Tumors
Memorial Sloan Kettering Cancer Center
NCT01449370 COMPLETED Dose Escalation Study of TAK-117 (MLN1117) in Subjects With Advanced Cancer
Millennium Pharmaceuticals, Inc.
NCT01884584 COMPLETED Potential Use of Indocyanine Green as a Fluorescent Agent for Definition of Surgical Margins in Cancer
Emory University
NCT01390818 COMPLETED Trial of MEK Inhibitor and PI3K/mTOR Inhibitor in Subjects With Locally Advanced or Metastatic Solid Tumors
EMD Serono
NCT01005797 COMPLETED Study of Panobinostat in Combination With Sorafenib in Kidney, Soft Tissue or Lung Cancers
Medical University of South Carolina
NCT02216669 WITHDRAWN Trial to Determine Optimal Phase II Dose of the Oral Dual CAIX Inhibitor/ Radiosensitizer
Maastricht Radiation Oncology
NCT02836821 COMPLETED Effect of Rifampicin on the Pharmacokinetics of Apatinib
Jiangsu HengRui Medicine Co., Ltd.
NCT02836171 COMPLETED Effect of Itraconazole on the Pharmacokinetics of Apatinib
Jiangsu HengRui Medicine Co., Ltd.
NCT03062982 COMPLETED Food-Effect and Metabolism Study in Healthy Subjects
Jiangsu HengRui Medicine Co., Ltd.
NCT01853046 COMPLETED Pharmacokinetics and Safety of Regorafenib (BAY73-4506) in Cancer Subjects With Severe Renal Impairment
Bayer
NCT02331381 TERMINATED Imaging and Plan Workflow in a Novel Low-Field Magnetic Resonance Imaging (MRI) Radiotherapy Device
Washington University School of Medicine
NCT01287546 COMPLETED A Study of LY2875358 in Participants With Advanced Cancer
Eli Lilly and Company
NCT01504490 TERMINATED Phase I Study of CS-7017 and Bexarotene
Georgetown University
NCT01299701 TERMINATED A Single Center Study to Characterize the Absorption, Distribution, Metabolism and Excretion (ADME) of ASA404 After a Single Infusion in Patients With Solid Tumors
Novartis Pharmaceuticals
NCT02262455 COMPLETED Effects of STM 434 Alone or in Combination With Liposomal Doxorubicin in Patients With Ovarian Cancer or Other Advanced Solid Tumors
Santa Maria Biotherapeutics
NCT01300026 COMPLETED AMG 319 Lymphoid Malignancy FIH
Amgen
NCT02718378 COMPLETED Evaluation of Safety and Efficacy of Estetrol in Healthy Men
Pantarhei Oncology B.V.
NCT02257476 COMPLETED Extended Infusion Carfilzomib on a Weekly Schedule in Patients With Advanced Solid Tumors
Emory University
NCT02048709 COMPLETED Indoleamine 2,3-Dioxygenase (IDO) Inhibitor in Advanced Solid Tumors
Genentech, Inc.
NCT02536469 COMPLETED HuMax-IL8 (Interleukin8) in Patients With Advanced Malignant Solid Tumors
Bristol-Myers Squibb
NCT01088464 COMPLETED Study of IMC-11F8 in Participants With Advanced Solid Tumors
Eli Lilly and Company
NCT02640365 COMPLETED A Dose Escalation Study of MM-398 Plus Irinotecan in Patients With Unresectable Advanced Cancer
GERCOR - Multidisciplinary Oncology Cooperative Group
NCT01604759 COMPLETED Polarized Reflectance Spectroscopy for Oral Lesions
British Columbia Cancer Agency
NCT02078089 TERMINATED Oxcarbazepine Plus Morphine in Patients With Refractory Cancer Pain
Costantine Albany
NCT01991938 TERMINATED Phase I Dose Escalation Study of VS-5584 in Subjects With Advanced Non-Hematologic Malignancies or Lymphoma
Verastem, Inc.
NCT01482377 COMPLETED A Study of RO5479599 Alone or in Combination With Cetuximab or Erlotinib in Participants With Metastatic and/or Locally Advanced Malignant Human Epidermal Growth Factor Receptor (HER3) Expressing Solid Tumors of Epithelial Cell Origin
Hoffmann-La Roche
NCT01406119 COMPLETED An Extension Study of ABT-806 in Subjects With Advanced Solid Tumors
AbbVie (prior sponsor, Abbott)
NCT01980667 COMPLETED Study of Lurbinectedin (PM01183) in Combination With Cisplatin in Patients With Solid Tumors
PharmaMar
NCT00787033 COMPLETED A Study Of PF-04554878 In Patients With Advanced Non-Hematologic Malignancies
Verastem, Inc.
NCT01837667 COMPLETED Phase I Study of LB-100 With Docetaxel in Solid Tumors
Lixte Biotechnology Holdings, Inc.
NCT01308944 COMPLETED Therapeutic Targeting of Stress Factors in Ovarian Cancer Patients
Washington University School of Medicine
NCT00949949 COMPLETED Everolimus, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Unresectable Solid Tumors Refractory to Standard Therapy
Mayo Clinic
NCT01188252 COMPLETED Clinical Study to Evaluate the Maximum Tolerated Dose of BAY1000394 Given in a 3 Days on / 4 Days Off Schedule in Subjects With Advanced Malignancies
Bayer
NCT00725933 COMPLETED Administration of BIIB028 to Subjects With Solid Tumors
Biogen
NCT00555724 COMPLETED Phase 1 Study of BIIB022 (Anti-IGF-1R Monoclonal Antibody) in Relapsed/Refractory Solid Tumors
Biogen
NCT00970411 COMPLETED Study of KRN951 in Patients With Solid Tumors
Kyowa Kirin Co., Ltd.
NCT00996892 TERMINATED Safety, Tolerability and Pharmacokinetics of Cobimetinib in Combination With Pictilisib in Patients With Locally Advanced or Metastatic Solid Tumors
Genentech, Inc.
NCT00741403 COMPLETED A Open Label Phase I/II Clinical Trial to Evaluate CPI-613 in Patients With Advanced Malignancies
Cornerstone Pharmaceuticals
NCT00618735 COMPLETED Once or Twice Daily Administration of BIIB021 to Subjects With Advanced Solid Tumors
Biogen
NCT01915576 COMPLETED Phase I Dose Escalation Study With an Allosteric AKT 1/2 Inhibitor in Patients
Bayer
NCT01204450 TERMINATED Temsirolimus and Valproic Acid in Treating Young Patients With Relapsed Neuroblastoma, Bone Sarcoma, or Soft Tissue Sarcoma
UNC Lineberger Comprehensive Cancer Center
NCT01976143 COMPLETED A Study in Cancer Patients to Evaluate the Effect of a Single Dose of NKTR-102 (Etirinotecan Pegol) on the QTc Interval and to Assess Pharmacokinetics and Safety
Nektar Therapeutics
NCT01832298 COMPLETED Study of Simmitecan Hydrochloride in the Treatment of Advanced Solid Tumor
Haihe Biopharma Co., Ltd.
NCT01967043 COMPLETED A Study to Evaluate Safety, Tolerability, Pharmacokinetics and Activity of Oraxol in Subjects With Advanced Malignancies
Kinex Pharmaceuticals Inc.
NCT00892567 COMPLETED Evaluating the T Cell Response to a Peptide-based Vaccine in Patients With Breast Cancer
Craig L Slingluff, Jr
NCT02264886 COMPLETED Adaptive MRI-Guided SBRT for Unresectable Primary or Oligometastatic Central Thorax and Abdominal Malignancies
Washington University School of Medicine
NCT02112162 TERMINATED Gene Expression and FDG PET/MRI in Evaluating Treatment Response in Patients With Locally Advanced Rectal Cancer Undergoing Chemotherapy and Radiation Therapy Before Surgery
Washington University School of Medicine
NCT00637390 TERMINATED A Phase I Study of Alemtuzumab in Patients With Relapsed Ovarian/Primary Peritoneal Cancer.
University of Michigan Rogel Cancer Center
NCT02442063 COMPLETED Phase Ib Study of Radium Ra 223 Dichloride in Combination With Paclitaxel in Cancer Subjects With Bone Lesions
Bayer
NCT02353026 COMPLETED Phase I Study of Intravenous Artesunate for Solid Tumors
Georgetown University
NCT02081495 COMPLETED A Study of DOXIL/CAELYX in Patients With Advanced or Refractory Solid Malignancies Including Patients With Ovarian Cancer
Janssen Research & Development, LLC
NCT01773434 COMPLETED A Phase 1 Study of MORAb-004 in Patients With Solid Tumor (Study: MORAb-004-J081-103)
Eisai Co., Ltd.
NCT01462175 COMPLETED A First-In-Human Study of RO5503781 in Participants With Advanced Malignancies Except Leukemia
Hoffmann-La Roche
NCT01164033 COMPLETED A Study of RO5045337 in Patients With Solid Tumors
Hoffmann-La Roche
NCT01358903 COMPLETED A Study of RO5429083 in Patients With Metastatic and/or Locally Advanced, CD44-Expressing, Malignant Solid Tumors
Hoffmann-La Roche
NCT01356173 COMPLETED Evaluating the Safety and Tolerability of GDC-0349 in Patients With Locally Advanced or Metastatic Solid Tumors or Non Hodgkin's Lymphoma
Genentech, Inc.
NCT00985374 TERMINATED A Multiple Ascending Dose Study of the mTOR Inhibitor (RAD001) in Combination With R1507 in Patients With Advanced Solid Tumors
Hoffmann-La Roche
NCT00773526 COMPLETED A Dose-Escalation Study of RO5126766 in Patients With Advanced Solid Tumors.
Hoffmann-La Roche
NCT01363024 COMPLETED Trial Evaluating the Safety and Pharmacokinetics of MFGR1877S in Patients With Advanced Solid Tumors
Genentech, Inc.
NCT01974258 WITHDRAWN Safety, Tolerability, and Pharmacokinetics of Onartuzumab Combined With Vemurafenib and/or Cobimetinib in Cancer Patients
Hoffmann-La Roche
NCT00623870 COMPLETED A Study of RO5045337 [RG7112] in Patients With Hematologic Neoplasms.
Hoffmann-La Roche
NCT00721266 COMPLETED A Dose-Escalation Study of RO5083945 in Patients With Metastatic and/or Locally Advanced Malignant Epidermal Growth Factor Receptor (EGFR)+ Solid Tumors.
Hoffmann-La Roche
NCT01383733 COMPLETED A Study of RO5458640 in Patients With Advanced Solid Tumors
Hoffmann-La Roche
NCT02536391 COMPLETED Ipatasertib (GDC-0068) Study to Evaluate Formulation Change and Food Effect on Bioavailability in Healthy Subjects
Genentech, Inc.
NCT00811993 TERMINATED A Study of R1507 in Combination With Multiple Standard Chemotherapy Treatments in Patients With Advanced Solid Tumors
Hoffmann-La Roche
NCT01283178 TERMINATED Phase I Study of IMRT and Molecular-Image Guided Adaptive Radiation Therapy for Advanced HNSCC
Virginia Commonwealth University
NCT01605916 COMPLETED Investigate the Safety and Tolerability of AZD6244 Monotherapy or + Docetaxel in Japanese Patients With Advanced Solid Malignancies or Non-Small Cell Lung Cancer
AstraZeneca
NCT02134340 COMPLETED A Safety and Biodistribution Study of [I-124]-CPD-1028 Injection in Solid Tumours
Centre for Probe Development and Commercialization
NCT01565746 COMPLETED Safety, Biodistribution, Radiation Dosimetry and Pharmacokinetics Study of BAY88-8223 in Japanese Patients
Bayer
NCT01497470 COMPLETED A Clinical Study in Cancer Patients to Investigate the Potential Impact of Custirsen, on the Blood Levels of the Chemotherapeutic Drug, Paclitaxel, When Given Together as Part of a Treatment Regimen
Achieve Life Sciences
NCT02380313 WITHDRAWN Dose-Finding Study of Afuresertib Administered in Combination With Either Enzalutamide or Aibraterone
GlaxoSmithKline
NCT01522820 COMPLETED Vaccine Therapy With or Without Sirolimus in Treating Patients With NY-ESO-1 Expressing Solid Tumors
Roswell Park Cancer Institute
NCT00884546 COMPLETED Multiple Ascending Dose (MAD) Combination in Subjects With Multiple Myeloma
Bristol-Myers Squibb
NCT01384253 COMPLETED Safety Study of ²¹²Pb-TCMC-Trastuzumab Radio Immunotherapy
Orano Med LLC
NCT01457417 COMPLETED A Study of DKN-01 in Multiple Myeloma or Advanced Solid Tumors
Leap Therapeutics, Inc.
NCT02033551 COMPLETED A Study Evaluating Veliparib as a Single Agent or in Combination With Chemotherapy in Subjects With Solid Tumors
AbbVie
NCT02260544 COMPLETED Bioequivalence Study of Doxorubicin Hydrochloride Liposome Injection
Dr. Reddy's Laboratories Limited
NCT01413022 COMPLETED FOLFIRINOX Plus PF-04136309 in Patients With Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma
Washington University School of Medicine
NCT01986218 TERMINATED Phase I Ascending Multiple-Dose Study of BMS-986115 in Subjects With Advanced Solid Tumors
Bristol-Myers Squibb
NCT01447225 COMPLETED Safety Study of MM-121 in Combination With Multiple Anticancer Therapies in Patients With Advanced Solid Tumors
Merrimack Pharmaceuticals
NCT02150135 COMPLETED Effect of Oncothermia on Improvement of Quality of Life in Unresectable Pancreatic Cancer Patients
Seoul National University Hospital
NCT01352884 COMPLETED Study to Assess the Safety, Tolerability, and Pharmacokinetics of AMP-224 in Patients With Advanced Cancer
MedImmune LLC
NCT00734305 COMPLETED Phase I Safety Study of the Drug MM-121 in Patients With Advanced Solid Tumors Resisting Ordinary Treatment
Merrimack Pharmaceuticals
NCT02126527 WITHDRAWN Auranofin and Sirolimus in Treating Patients With Advanced Solid Tumors or Recurrent Non-Small Cell Lung Cancer
Mayo Clinic
NCT01682135 COMPLETED A Study in Participants With Advanced Solid Tumors
Eli Lilly and Company
NCT02876627 COMPLETED Effect Aerobic Training on Women With Breast Cancer After Chemotherapy
University of Isfahan
NCT01851096 COMPLETED Safety and Pharmacology Study of SNX-5422 in Subjects With Resistant Lung Adenocarcinoma
Esanex Inc.
NCT02867397 COMPLETED Study of Teysuno (S-1) Combined With Epirubicin and Oxaliplatin in Patients With Advanced Solid Tumors
Disphar International B.V.
NCT00736619 COMPLETED Weekly Nanoparticle Albumin-Bound Paclitaxel (Abraxane) + Weekly Cetuximab + Radiation Therapy (IMRT, Intensity-Modulated Radiation Therapy) in Patients With Stage III-IVB Head and Neck Squamous Cell Carcinoma (HNSCC)
Memorial Sloan Kettering Cancer Center
NCT02276768 COMPLETED Study on Analgesia of GIC-1001 & GIC-1002 on Visceral Pain, Rectal Sensory Threshold Using the Barostat Method
gicare Pharma Inc.
NCT01528137 TERMINATED Talactoferrin in Treating Patients With Relapsed or Refractory Non-Small Cell Lung Cancer or Squamous Cell Head and Neck Cancer
Stanford University
NCT02845999 COMPLETED Allogenic Immunotherapy Based on Natural Killer (NK) Cell Adoptive Transfer in Metastatic Gastrointestinal Carcinoma Treated With Cetuximab
Centre Hospitalier Universitaire de Besancon
NCT02317419 TERMINATED A Study of RO6927005 Either As Monotherapy (Part A) or in Combination With Gemcitabine and Nab-Paclitaxel (Part B) to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Clinical Activity in Patients With Mesothelin-positive Metastatic and/or Locally Advanced Malignant Solid Tumors
Hoffmann-La Roche
NCT02063230 COMPLETED To Assess the Pharmacokinetics, Safety and Tolerability of Selumetinib in Patients With Hepatic Impairment and Healthy Subjects
AstraZeneca
NCT01007695 TERMINATED Molecular Signature of Valproic Acid in Breast Cancer With Functional Imaging Assessment - a Pilot
University of Utah
NCT01986166 COMPLETED A Study of MEHD7945A and Cobimetinib in Patients With Locally Advanced or Metastatic Cancers With Mutant KRAS
Genentech, Inc.
NCT01325558 COMPLETED A Study of ALT-836 in Combination With Gemcitabine for Locally Advanced or Metastatic Solid Tumors
Altor BioScience
NCT02390154 COMPLETED Roniciclib Mass Balance Study
Bayer
NCT02018874 COMPLETED A Phase Ib Study of the Safety, Tolerability and Efficacy of LY2780301 in Combination With Gemcitabine
Gustave Roussy, Cancer Campus, Grand Paris
NCT01532011 COMPLETED Erlotinib in Combination With Pralatrexate in Advanced Malignancies
M.D. Anderson Cancer Center
NCT01213160 COMPLETED Study to Assess Safety and Tolerability of AZD4547 in Japanese Patient
AstraZeneca
NCT01284192 COMPLETED Study of an Investigational Drug, ASP3026, in Patients With Advanced Malignancies (Solid Tumors and B-Cell Lymphoma)
Astellas Pharma Inc
NCT01578564 COMPLETED Safety and Tolerability Study of SOR-C13 in Subjects With Advanced Cancers Commonly Known to Express the TRPV6 Channel
Soricimed Biopharma Inc
NCT01431547 COMPLETED Study of Dalotuzumab Alone and With Ridaforolimus in Pediatric Participants With Advanced Solid Tumors (MK-8669-062 AM1)
Merck Sharp & Dohme LLC
NCT02122809 COMPLETED Phase I Study of Chiauranib in Patients With Advanced Solid Tumors
Chipscreen Biosciences, Ltd.
NCT01155258 COMPLETED Temsirolimus and Vinorelbine Ditartrate in Treating Patients With Unresectable or Metastatic Solid Tumors
University of Southern California
NCT02076230 COMPLETED A Phase 1 TH-302 Mass Balance Trial
Merck KGaA, Darmstadt, Germany
NCT01912222 COMPLETED Pharmacokinetic Study of Oral IXAZOMIB in Cancer Patients With Liver Dysfunction
Millennium Pharmaceuticals, Inc.
NCT00933777 COMPLETED SORAVE - Sorafenib and Everolimus in Solid Tumors
University of Cologne
NCT02054754 COMPLETED Assessment of Single Doses of Oral Dexanabinol in Healthy Subjects
e-Therapeutics PLC
NCT01546519 COMPLETED A Study of Vismodegib in Patients With Advanced Solid Malignancies Including Hepatocellular Carcinoma With Varying Degrees of Renal or Hepatic Function
Genentech, Inc.
NCT01349296 COMPLETED BIBF 1120 and RAD001 in Solid Tumors - Phase I
University of Cologne
NCT00658658 COMPLETED Panitumumab in Children With Solid Tumors
Amgen
NCT01202032 COMPLETED Multicenter Dose-escalation Study of a Combination of Pazopanib and Bevacizumab in Patients With Metastatic Renal Cell Carcinoma or Others Advanced Solid Tumors
Centre Leon Berard
NCT01418677 COMPLETED An Open-Label Study to Assess the Pharmacokinetics and Safety of HALAVEN in Subjects With Cancer Who Also Have Impaired Renal Function
Eisai Inc.
NCT01778920 COMPLETED Pilot and Feasibility Study of the Imaging Potential of EC17: Intraoperative Folate-fluorescein Conjugate (EC17) Lung Cancer (CA)
University of Pennsylvania
NCT01242605 COMPLETED ABC-04 a Study of Cisplatin, Gemcitabine and Selumetinib in Patients With Advanced Biliary Tract Cancer
University College, London
NCT01327313 COMPLETED A Study of EMD525797 in Solid Tumor Patients in Japan
Merck KGaA, Darmstadt, Germany
NCT01115790 COMPLETED A Phase 1 Study in Participants With Advanced Cancer
Eli Lilly and Company
NCT01212380 COMPLETED Study of Carfilzomib in Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL) or Prolymphocytic Leukemia (PLL)
Ohio State University Comprehensive Cancer Center
NCT00876044 COMPLETED A Study to Evaluate the Effects of Aflibercept on QTc Interval in Cancer Patients
Sanofi
NCT01110603 TERMINATED A Study of MK-4827 in Combination With Standard Chemotherapy in Participants With Advanced Solid Tumors (MK-4827-008 AM1)
Tesaro, Inc.
NCT02235740 TERMINATED A Study Conducted in Subjects With Relapsed/Refractory Multiple Myeloma (MM); to Determine Dose of Afuresertib in Combination With Carfilzomib (Part 1) and to Investigate the Safety, Pharmacokinetic and Clinical Activity of the Combination Compared With Carfilzomib Alone (Part 2)
Novartis
NCT01353781 COMPLETED Open Label Phase 1 Study in Japan for Patient With Advanced Solid Malignancies
AstraZeneca
NCT01391533 COMPLETED Study of SAR125844 Single Agent Administered as Slow Intravenous Infusion in Adult Patients With Advanced Malignant Solid Tumors
Sanofi
NCT02531919 COMPLETED Extended Use of Sodium Bicarbonate in Patients With Cancer
University of Arizona
NCT01711034 COMPLETED A Phase 1, Open-label, Multiple Dose Escalation Trial to Determine Safety and Tolerability of Once Daily OPB-111077 in Subjects With Advanced Cancer
Otsuka Pharmaceutical Development & Commercialization, Inc.
NCT02221505 TERMINATED Phase 1 Study of LOP628 in Adult Patients With cKit-positive Solid Tumors and Acute Myeloid Leukemia
Novartis Pharmaceuticals
NCT01357330 COMPLETED Oral SAR245408 (XL147) and Oral MSC1936369B in Patients With Locally Advanced or Metastatic Solid Tumors
Sanofi
NCT01182168 COMPLETED Gemcitabine and Split-Dose Cisplatin Plus Everolimus (RAD001) in Patients With Advanced Solid Tumor Malignancies
Memorial Sloan Kettering Cancer Center
NCT01562275 COMPLETED A Study Evaluating the Safety, Tolerability, and Pharmacokinetics of GDC-0973 in Combination With GDC-0068 When Administered in Participants With Locally Advanced or Metastatic Solid Tumors
Genentech, Inc.
NCT02220049 COMPLETED Dose Escalation of Velcade Daily Dose in Patients With Solid Tumors
Gustave Roussy, Cancer Campus, Grand Paris
NCT01634893 COMPLETED Oral Hydroxychloroquine Plus Oral Sorafenib to Treat Patients With Refractory or Relapsed Solid Tumors
The University of Texas Health Science Center at San Antonio
NCT01930292 TERMINATED Debio 1143 in Combination With Carboplatin and Paclitaxel in Patient With Advanced Solid Malignancies
Debiopharm International SA
NCT01446458 COMPLETED Phase I Study of Stereotactic Body Radiation Therapy and FOLFIRINOX in the Neoadjuvant Therapy of Pancreatic Cancer
Emory University
NCT00632424 TERMINATED Phase 1 Trial of Oral Ixabepilone
R-Pharm
NCT01683149 COMPLETED Sorafenib and Topotecan in Refractory/Recurrent Pediatric Malignancies
H. Lee Moffitt Cancer Center and Research Institute
NCT00798200 COMPLETED Community Based Exercise Program for Well Cancer Survivors
Hamilton Health Sciences Corporation
NCT00993239 COMPLETED Dose Escalation Safety Study of TL32711 in Adults With Refractory Solid Tumors or Lymphoma
TetraLogic Pharmaceuticals
NCT02432612 WITHDRAWN A Study to Assess the Pharmacokinetic (PK) Properties of Sativex® in Patients With Advanced Cancer
GW Pharmaceuticals Ltd
NCT00985777 COMPLETED Vitamin E δ-Tocotrienol Administered to Subjects With Resectable Pancreatic Exocrine Neoplasia
H. Lee Moffitt Cancer Center and Research Institute
NCT01791374 COMPLETED Phase 1/1b Study of Rilotumumab in Japanese Subjects With Advanced Solid Tumors or Advanced or Metastatic Gastric or GEJ
Amgen
NCT01665183 COMPLETED Ph 1 Trial of ADI-PEG 20 Plus Cisplatin in Patients With Metastatic Melanoma
Polaris Group
NCT01664000 COMPLETED A Safety, Pharmacokinetic and Pharmacodynamic Study of Kevetrin in Patients With Advanced Solid Tumors
Cellceutix Corporation
NCT01450384 COMPLETED Pemetrexed Disodium and Sorafenib Tosylate in Treating Patients With Advanced Solid Tumors
Virginia Commonwealth University
NCT01693445 COMPLETED S-1, Oxaliplatin, and Irinotecan for Advanced Gastrointestinal Cancer
Hallym University Medical Center
NCT00714181 COMPLETED Hydroxychloroquine and Temozolomide in Treating Patients With Metastatic or Unresectable Solid Tumors
Abramson Cancer Center at Penn Medicine
NCT01497626 TERMINATED Lapatinib and Bortezomib in Patients With Advanced Malignancies
Georgetown University
NCT02470559 WITHDRAWN Activated T-cell Therapy, Low-Dose Aldesleukin, and Sargramostim in Treating Patients With Ovarian, Fallopian Tube, or Primary Peritoneal Cancer That is Stage III-IV, Refractory, or Recurrent
Barbara Ann Karmanos Cancer Institute
NCT02537561 WITHDRAWN Talazoparib in Combination With Gemcitabine and Cisplatin in Patients With Advanced Solid Tumors
Washington University School of Medicine
NCT02154646 COMPLETED A Study of LY2157299 in Participants With Pancreatic Cancer That is Advanced or Has Spread to Another Part of the Body
Eli Lilly and Company
NCT02444884 COMPLETED MLN8237 to Treat Children With Relapsed/Refractory Solid Tumors
Children's Oncology Group
NCT01300533 COMPLETED A Study of BIND-014 Given to Patients With Advanced or Metastatic Cancer
BIND Therapeutics
NCT01883635 COMPLETED Exercise Intervention for Cancer Survivors and Caregivers
University of Rochester
NCT00732836 COMPLETED Hepatic Arterial Infusion (HAI) of Abraxane
M.D. Anderson Cancer Center
NCT00920868 COMPLETED XAD - Xelox (Capecitabine + Oxaliplatin) + Bevacizumab + Dasatinib
Herbert Hurwitz, MD
NCT02131506 TERMINATED A Study of Lapatinib in Combination With Caelyx in Patients With Advanced HER2 Positive Pretreated Breast Cancer
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
NCT00869895 COMPLETED A Dose-Finding Study of E7050 Administered Orally to Patients With Advanced Solid Tumors
Eisai Inc.
NCT02292732 WITHDRAWN A Pharmacokinetics (PK) and Safety Study to Determine the Effect of Repeat Dosing of Trametinib on Combined Oral Contraceptive (Norethindrone Plus Ethinyl Estradiol) in Female Subjects With Solid Tumors
GlaxoSmithKline
NCT02096341 TERMINATED A Phase 1 Pilot Study of the Subcutaneous (s.c.) Route to Facilitate the Administration of RRx-001
EpicentRx, Inc.
NCT01018784 COMPLETED A Study of MORAb-009 in Patients With Solid Tumor
Eisai Co., Ltd.
NCT01118819 TERMINATED Safety Study of Clostridium Novyi-NT Spores to Treat Patients With Solid Tumors That Have Not Responded to Standard Therapies
BioMed Valley Discoveries, Inc
NCT01405391 COMPLETED Study of PM01183 in Non-Colorectal Cancer Patients as a Days 1 and 8 Intravenous Short Infusion Every 3 Weeks
PharmaMar
NCT01940172 COMPLETED Study of Birinapant in Combination With Conatumumab in Subjects With Relapsed Ovarian Cancer
TetraLogic Pharmaceuticals
NCT01748721 COMPLETED MORAb-004 in Treating Young Patients With Recurrent or Refractory Solid Tumors or Lymphoma
Morphotek
NCT02563951 COMPLETED Study of Granisetron Hydrochloride Nasal Spray (GNS) in Healthy Volunteers
Maxinase Life Sciences Ltd.
NCT01012427 COMPLETED Percutaneous Renal Tumor Cryoablation Followed by Biopsy
Memorial Sloan Kettering Cancer Center
NCT02004548 COMPLETED Phase I Clinical Study of Metatinib Tromethamine Tablet
Jiangsu Simcere Pharmaceutical Co., Ltd.
NCT00574977 COMPLETED Safety Study of Modified Vaccinia Virus to Cancer
David Bartlett
NCT00671411 COMPLETED Evaluating Renal Masses Using Ultrasound Intravenous Microbubble Contrast
Memorial Sloan Kettering Cancer Center
NCT01095848 COMPLETED A Phase I Safety Study of a Cancer Vaccine to Treat HLA-A2 Positive Advanced Stage Ovarian, Breast and Prostate Cancer
ImmunoVaccine Technologies, Inc. (IMV Inc.)
NCT01056029 COMPLETED Dose-Escalation Phase 1 Study of G-202 (Mipsagargin) in Patients With Advanced Solid Tumors
GenSpera, Inc.
NCT01335269 COMPLETED A Study of BI 853520 in Patients With Various Types of Advanced or Metastatic Cancer
Boehringer Ingelheim
NCT01815294 COMPLETED A Pivotal Bioequivalence Study of DOXIL/CAELYX (Doxorubicin HCL) in Patients With Advanced or Refractory Solid Malignancies Including Patients With Ovarian Cancer
Janssen Research & Development, LLC
NCT00669136 TERMINATED Immunization With AFP + GM CSF Plasmid Prime and AFP Adenoviral Vector Boost in Patients With Hepatocellular Carcinoma
Lisa H. Butterfield, Ph.D.
NCT01809912 TERMINATED Safety Study of MG1102 in Patients With Solid Tumors
Green Cross Corporation
NCT01004822 TERMINATED A Safety, Tolerability, And Pharmacokinetic Trial With CVX-241 In Patients With Advanced Solid Tumors
Pfizer
NCT01626001 COMPLETED Imaging Study Compare 4DCT Image
M.D. Anderson Cancer Center
NCT01152203 COMPLETED Bendamustine and Bevacizumab for Advanced Cancers
M.D. Anderson Cancer Center
NCT00940381 COMPLETED Sirolimus and Cetuximab in Advanced Malignancies
M.D. Anderson Cancer Center
NCT01122615 COMPLETED Sunitinib Plus Temsirolimus in Patients With Renal Cell Cancer (RCC)
M.D. Anderson Cancer Center
NCT00980239 COMPLETED HAI Irinotecan + IV Bevacizumab, Bevacizumab & Oxaliplatin or Bevacizumab & Cetuximab in Advanced Cancers Metastatic to Liver
M.D. Anderson Cancer Center
NCT00877474 COMPLETED Phase I, Multicenter, Open-label, Dose-escalating, Clinical and Pharmacokinetic Study of PM01183 in Patients With Advanced Solid Tumors
PharmaMar
NCT00678769 COMPLETED Cixutumumab and Temsirolimus in Treating Patients With Locally Advanced or Metastatic Cancer
National Cancer Institute (NCI)
NCT01245543 WITHDRAWN Safety Study for Intravenous (IV) AC480 (AC480IV) to Treat Advanced Solid Tumors
Daiichi Sankyo
NCT01299636 COMPLETED Study of PM060184 in Patients With Advanced Solid Tumors
PharmaMar
NCT01293630 COMPLETED A Dose-escalation Study of Ombrabulin in Combination With Paclitaxel and Carboplatin in Patients With Advanced Solid Tumors
Sanofi
NCT01833923 COMPLETED A Phase I Study of Anlotinib on Tolerance and Pharmacokinetics
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NCT00932126 TERMINATED This Is The First Study Using Escalating Doses Of PF-03758309, An Oral Compound, In Patients With Advanced Solid Tumors
Pfizer
NCT01337050 COMPLETED Asian Phase I Study Of PF-03446962
Pfizer
NCT01685489 WITHDRAWN A Phase 1b Dose Escalation Trial of PSK®/Placebo With Docetaxel to Treat Metastatic Castration-resistant Prostate Cancer
Bastyr University
NCT01265927 COMPLETED A Study Inhibiting Telomerase to Reverse Trastuzumab Resistance in HER2+ Breast Cancer
Indiana University
NCT01585870 COMPLETED Safety, Pharmacokinetics, Pharmacodynamics and Anti-tumor Activity of Sorafenib and Eribulin in Combination
Bayer
NCT01128998 COMPLETED Sorafenib Plus S-1 in Advanced Solid Tumors
National Health Research Institutes, Taiwan
NCT00756340 COMPLETED A Trial of Everolimus and Bevacizumab in Children With Recurrent Solid Tumors
St. Jude Children's Research Hospital
NCT01253681 COMPLETED Study of AMG 386 in Combination With Paclitaxel and Carboplatin in Subjects With Ovarian Cancer
Amgen
NCT00884676 COMPLETED Ixabepilone and Sunitinib Malate in Treating Patients With Progressive Advanced Solid Tumors
Jaime Merchan
NCT01054313 COMPLETED Docetaxel and Sirolimus in Patients With Advanced Malignancies
M.D. Anderson Cancer Center
NCT02462707 WITHDRAWN A Study Of PF-03084014 In Japanese Patients With Advanced Solid Tumors
Pfizer
NCT01548482 COMPLETED Trebananib And Temsirolimus in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery
National Cancer Institute (NCI)
NCT01963715 TERMINATED A Phase 1 Study of IMGN289 in Adult Patients With EGFR-positive Solid Tumors
ImmunoGen, Inc.
NCT00770536 COMPLETED AMG386 Comb w. Either Pegylated Liposomal Doxorubicin or Topotecan Subjects w. Advanced Recurrent Epithelial Ovarian CR
Amgen
NCT01317927 COMPLETED A Study of Belinostat in Combination With Warfarin in Patients With Solid Tumors or Hematological Malignancies
Spectrum Pharmaceuticals, Inc
NCT02525536 COMPLETED A Phase 1 Study Evaluating the Safety, Tolerability and Pharmacokinetics of Trebananib (AMG 386 ) in Adult Japanese Participants With Advanced Solid Tumors
Takeda
NCT01560325 COMPLETED Safety Study of Increasing Doses of CKD-516 in Patients With Advanced Solid Cancers
Chong Kun Dang Pharmaceutical
NCT01071018 COMPLETED A Study of MK2206 in Locally Advanced or Metastatic Solid Tumors (2206-007)
Merck Sharp & Dohme LLC
NCT00729664 COMPLETED Multiple Ascending Dose (MDX1105-01)
Bristol-Myers Squibb
NCT00817518 COMPLETED A Dose-Escalating Study of RO4987655 in Patients With Advanced Solid Tumors
Hoffmann-La Roche
NCT00792558 WITHDRAWN Ascending Multiple-Dose Study of BMS-817378 in Subjects With Advanced Cancers
Bristol-Myers Squibb
NCT01295632 COMPLETED Safety and Tolerability of Different Dose Combinations of Ridaforolimus With MK-2206 or MK-0752 for Participants With Advanced Cancer (MK-8669-049)
Merck Sharp & Dohme LLC
NCT01584284 COMPLETED Safety Study of Attenuated Vaccinia Virus (GL-ONC1)With Combination Therapy in Head & Neck Cancer
Genelux Corporation
NCT00796484 TERMINATED Safety Study of Pharmacokinetics of XL888 in Adults With Solid Tumors
Exelixis
NCT01553656 COMPLETED Dose-Finding Study of Cabozantinib (XL184) in Japanese Subjects With Advanced Cancer
Exelixis
NCT00704392 WITHDRAWN Safety Study of XL647 and XL147 Administered in Combination Daily in Adults With Solid Tumors
Exelixis
NCT00998296 COMPLETED Phase I Dose Escalation Study of Concomitant BIBF 1120 and BIBW 2992 in Patients With Advanced Solid Tumours.
Boehringer Ingelheim
NCT01901172 COMPLETED A Study of the Drug-Drug Interaction of RO5503781 and Posaconazole, the Relative Bioavailability of New Formulations of RO5503781 and the Food-Effect on the Pharmacokinetics of RO5503781 in Patients With Solid Tumors
Hoffmann-La Roche
NCT02001909 COMPLETED Effect of Neomycin on the Pharmacokinetics of Regorafenib
Bayer
NCT00997022 COMPLETED Trial of Sorafenib in Hepatocellular Cancer (HCC) Transplant Patients
Columbia University
NCT01652794 COMPLETED Carboplatin, Gemcitabine Hydrochloride, and Stereotactic Body Radiation Therapy in Gynecological Cancer
Case Comprehensive Cancer Center
NCT01334073 COMPLETED Study of the Combination of Axitinib Plus Everolimus in Patients With Malignant Advanced Solid Tumors
University Hospital, Bordeaux
NCT01750580 COMPLETED Safety Study of BMS-986015 (Anti-KIR) in Combination With Ipilimumab in Subjects With Selected Advanced Tumor
Bristol-Myers Squibb
NCT02496949 COMPLETED A Phase Ib Study to Assess Safety and Efficacy of Oral Icaritin in Advanced Solid Tumors
Chinese Academy of Medical Sciences
NCT00895687 COMPLETED Study of Erlotinib in Combination With Bortezomib
M.D. Anderson Cancer Center
NCT00895128 COMPLETED Study of Erlotinib in Combination With Dasatinib
M.D. Anderson Cancer Center
NCT00798252 COMPLETED Ascending Multiple-Dose Study of Brivanib Alaninate in Combination With Chemotherapeutic Agents in Subjects With Advanced Cancers
Bristol-Myers Squibb
NCT02201823 COMPLETED Phase I/Ib Clinical Trial of ABTL0812 in Advanced Cancer Patients
Ability Pharmaceuticals SL
NCT01466569 COMPLETED An A/B Dose Escalation Study of AbGn-7 Alone and With FOLFOX7 Treatment in Patients With Advanced Solid Tumors
AbGenomics B.V Taiwan Branch
NCT01544322 COMPLETED Dose Escalation Study of the Safety and Pharmacokinetics of ME-344 Single Agent for Refractory Solid Tumors
MEI Pharma, Inc.
NCT01542047 TERMINATED A Combination of Pazopanib and Carboplatin in Advanced Solid Malignancies
New Mexico Cancer Research Alliance
NCT00947739 COMPLETED Phase I and Pharmacology Study of Camptothecin-20-O-Propionate Hydrate (CZ48) in Patients With Solid Tumors or Lymphoma
New Mexico Cancer Research Alliance
NCT01490047 WITHDRAWN Single Dose of Intravenous rhTNF-α and Liposomal Doxorubicin in Patients With Advanced Solid Tumors or Lymphomas
Ludwig Institute for Cancer Research
NCT01271972 COMPLETED Study of Nesvacumab (REGN910/ SAR307746)
Regeneron Pharmaceuticals
NCT00800150 TERMINATED Total Marrow and Total Lymph Node Irradiation, Fludarabine, and Melphalan Followed By Donor Stem Cell Transplant in Treating Patients With Advanced Hematological Cancer That Has Not Responded to Treatment
City of Hope Medical Center
NCT01602289 COMPLETED A Study of LY2875358 in Japanese Participants With Advanced Cancer
Eli Lilly and Company
NCT00709020 COMPLETED White Button Mushroom Extract in Preventing the Recurrence of Breast Cancer in Postmenopausal Breast Cancer Survivors
City of Hope Medical Center
NCT01846429 TERMINATED Oral Bicarbonate as Adjuvant for Pain Reduction in Patients With Tumor Related Pain
H. Lee Moffitt Cancer Center and Research Institute
NCT00770263 COMPLETED Erlotinib and Temsirolimus for Solid Tumors
Washington University School of Medicine
NCT01919710 COMPLETED Safety and Efficacy Studies of rHSA/GCSF Fusion Protein For Injection to Treat Neutropenia
Tianjin SinoBiotech Ltd.
NCT00951158 TERMINATED A Molecular Pharmacodynamic Dose-titration Trial of Conjugated Linoleic Acid (CLA; Clarinol®) in Patients With Advanced Solid Tumors
Dartmouth-Hitchcock Medical Center
NCT01434459 TERMINATED Study of Gemcitabine With TheraSphere® (Yttrium-90)in Patients With Hepatic Tumors of Pancreatobiliary Origin
Emory University
NCT01463982 COMPLETED Phase I of OratecanTM in Combination With Capecitabine in Patients With Advanced Solid Malignancies
Hanmi Pharmaceutical Company Limited
NCT02097875 COMPLETED Safety Study of a Fluorescent Marker to Visualize Cancer Cells
Blaze Bioscience Australia Pty Ltd
NCT01584544 COMPLETED Safety Study of Capecitabine With Radiation in Elderly Rectal Cancer
Chinese Academy of Medical Sciences
NCT00682279 WITHDRAWN A Phase I Study Of Oral Topotecan And Lapatinib In Subjects With Advanced Solid Tumors
GlaxoSmithKline
NCT01392521 COMPLETED Phase Ib Study of PI3(Phosphoinositol 3)-Kinase Inhibitor Copanlisib With MEK (Mitogen-activated Protein Kinase) Inhibitor Refametinib (BAY86-9766) in Patients With Advanced Cancer
Bayer
NCT00666081 WITHDRAWN Study to Investigate AKT Inhibitor GSK690693 in Subjects With Relapsed or Refractory Hematologic Malignancies
GlaxoSmithKline
NCT01065025 COMPLETED Open Label, Dose Escalation Trial of Oral Eg5 Kinesin-spindle Inhibitor 4SC-205 in Patients With Advanced Malignancies
4SC AG
NCT01529138 COMPLETED Study of Axitinib and Temsirolimus in Solid Tumors
Emory University
NCT01071304 COMPLETED Effect of Ridaforolimus on the Pharmacokinetics of Midazolam (Study MK-8669-044)
Merck Sharp & Dohme LLC
NCT00691548 COMPLETED Non-invasive Imaging of Cetuximab-Zr. 89 Uptake Wit PET: a Phase I Trial in Stage IV Cancer Patients
Maastricht Radiation Oncology
NCT01555242 COMPLETED A Study of Aneustat (OMN54) in Patients With Advanced Cancer and Lymphomas
Omnitura Therapeutics, Inc.
NCT01603979 COMPLETED A Phase 1 Dose Escalation Study of AV-203, an ERBB3 Inhibitory Antibody, in Subjects With Advanced Solid Tumors
AVEO Pharmaceuticals, Inc.
NCT01727869 COMPLETED Study of REGN1400 Alone and in Combination With Erlotinib or Cetuximab in Patients With Certain Types of Cancer
Regeneron Pharmaceuticals
NCT01268943 COMPLETED Study of Postoperative Concurrent Chemo-radiation With Capecitabine in Elderly Rectal Cancer Patients
Chinese Academy of Medical Sciences
NCT01970553 COMPLETED Escalating Doses of PM01183 in Combination With Gemcitabine in Patients With Specific Unresectable Solid Tumors
PharmaMar
NCT01081808 TERMINATED Laboratory-Treated Autologous Lymphocytes, Aldesleukin, and Sargramostim (GM-CSF) in Treating Advanced Solid Tumors
Roger Williams Medical Center
NCT01688960 COMPLETED Nesvacumab (REGN910/ SAR307746) and Aflibercept ("Ziv-aflibercept" in the U.S.) in Patients With Advanced Solid Malignancies
Regeneron Pharmaceuticals
NCT00888043 COMPLETED Safety/Biomarker Study of CNTO 95 and Avastin in Solid Tumors
Herbert Hurwitz, MD
NCT01234012 COMPLETED Study of IMF-001 in Patients With Malignancies Expressing NY-ESO-1
ImmunoFrontier, Inc.
NCT01629758 COMPLETED Safety Study of IL-21/Anti-PD-1 Combination in the Treatment of Solid Tumors
Bristol-Myers Squibb
NCT01334177 COMPLETED TLR8 Agonist VTX-2337 and Cetuximab in Treating Patients With Locally Advanced, Recurrent, or Metastatic Squamous Cell Cancer of Head and Neck
University of Washington
NCT01324115 TERMINATED NG-Nitro-L-Arginine in Treating Patients With Advanced Solid Tumors
Cancer Research UK
NCT01137552 TERMINATED A Phase 1 Dose Escalation Study of AMG 780 in Adult Subjects With Advanced Solid Tumors
Amgen
NCT01240408 COMPLETED E7080 Food Effect Study in Healthy Subjects
Eisai Inc.
NCT01495663 COMPLETED Dose Escalation Study of I-131-CLR1404 in Subjects With Cancer That Does Not Respond to Treatment or Has Returned
Cellectar Biosciences, Inc.
NCT00880568 COMPLETED Phase I Study of MK-1496 in Patients With Advanced Solid Tumor (MK-1496-002 AM 4)(COMPLETED)
Merck Sharp & Dohme LLC
NCT02312804 WITHDRAWN Ph Ib/BGJ398/Cervix and Other Solid Tumors
The University of Texas Health Science Center at San Antonio
NCT00704054 COMPLETED A Multi-Center Phase I Study of Intravenous Deforolimus (AP23573, MK-8669) Administered QDX5 Every Other Week in Pediatric Patients With Advanced Solid Tumors (8669-028)(COMPLETED)
Merck Sharp & Dohme LLC
NCT00781846 COMPLETED Trial of Deforolimus in Combination With Bevacizumab for Patients With Advanced Cancers (8669-010)(COMPLETED)
Merck Sharp & Dohme LLC
NCT01688791 TERMINATED A Study of MK-8109 (Vintafolide) Given Alone or With Chemotherapy in Participants With Advanced Cancers (MK-8109-001)
Endocyte
NCT02049281 TERMINATED A Study of Vintafolide (MK-8109) in Participants With Advanced Solid Tumor (MK-8109-011)
Endocyte
NCT00730379 COMPLETED A Combination Study With Ridaforolimus (MK8669) and Dalotuzumab (MK0646) in Patients With Advanced Cancer (8669-004)
Merck Sharp & Dohme LLC
NCT01417403 TERMINATED Hydroxychloroquine in Treating Patients With Solid Tumors Undergoing Radiation Therapy for Bone Metastases
Virginia Commonwealth University
NCT01844869 COMPLETED An Open-Label Study to Investigate the Pharmacokinetics of Omacetaxine Mepesuccinate
Teva Branded Pharmaceutical Products R&D, Inc.
NCT00879684 COMPLETED Safety And PK Study Of CVX-060 In Patients With Advanced Solid Tumors
Pfizer
NCT00959582 COMPLETED Positron Emission Tomography/Computed Tomography (PET/CT) in Relapsed Ovarian Cancer (MK-0000-143)
Merck Sharp & Dohme LLC
NCT01028755 COMPLETED To Determine Maximum Tolerated Dose of BAY79-4620 in Patients With Advanced Solid Tumors
Bayer
NCT01280487 COMPLETED A Safety Study of Oral ZSTK474 in Patients With Cancer
Zenyaku Kogyo Co., Ltd.
NCT00635596 COMPLETED Phase I Study of MT110 in Lung Cancer (Adenocarcinoma and Small Cell), Gastric Cancer or Adenocarcinoma of the Gastro-Esophageal Junction, Colorectal Cancer, Breast Cancer, Hormone-Refractory Prostate Cancer, and Ovarian Cancer
Amgen Research (Munich) GmbH
NCT00911898 COMPLETED A Study of MM-111 in Patients With Advanced, Refractory Her2 Amplified, Heregulin Positive Cancers
Merrimack Pharmaceuticals
NCT02048943 WITHDRAWN Dovitinib Lactate, Gemcitabine Hydrochloride, and Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced Solid Tumors or Pancreatic Cancer
Roswell Park Cancer Institute
NCT01097460 COMPLETED MM-111 in Combination With Herceptin in Patients With Advanced Her2 Amplified, Heregulin Positive Breast Cancer
Merrimack Pharmaceuticals
NCT01131234 COMPLETED Gamma-Secretase Inhibitor RO4929097 and Cediranib Maleate in Treating Patients With Advanced Solid Tumors
National Cancer Institute (NCI)
NCT01322438 COMPLETED Effect of Rifampin on the Pharmacokinetics of BAY73-4506
Bayer
NCT01026415 COMPLETED Clinical Pharmacology Study of Brentuximab Vedotin (SGN-35)
Seagen Inc.
NCT00813384 COMPLETED A Phase 1 Study of AMG 208 in Subjects With Advanced Solid Tumors
Amgen
NCT01340040 COMPLETED Dose-escalation Study to Assess Safety, Tolerability and Pharmacokinetics of MEDI-573 in Japanese Subjects
AstraZeneca
NCT02308631 COMPLETED Endoscopically Assisted Colostomy With Colopexy for Critically Ill Patients Without General Anesthesia or Laparotomy
University of Sao Paulo
NCT01193595 COMPLETED Dose-escalation, Safety, Pharmacokinetics Study of AVE8062 Combined With Bevacizumab in Patients With Advanced Solid Tumors
Sanofi
NCT00984425 COMPLETED The Treatment of Lapatinib in Combination With Sorafenib in Patients With Advanced Refractory Solid Tumors
Istituto Clinico Humanitas
NCT01329549 TERMINATED Dose Escalation Study of BIBF 1120 in Combination With Carboplatin and PLD in Relapsed Ovarian Cancer (OC)
Boehringer Ingelheim
NCT00667147 COMPLETED Phase I Abraxane Weekly and Three Weekly Schedule With Vandetanib
University of Southern California
NCT01165385 COMPLETED Study With Pazopanib in Combination With Cisplatin (CDDP) in Patients With Advanced Solid Tumors
UNICANCER
NCT01186601 COMPLETED Exploration of Tumor Accumulation of BAY94-9392 in Patients With Cancer
Life Molecular Imaging SA
NCT01238939 COMPLETED Study of NK012 and 5-FU/LV in Solid Tumors Followed by Dose Expansion in Colorectal Cancer
Nippon Kayaku Co., Ltd.
NCT01238952 COMPLETED Study of NK012 and Carboplatin in Solid Tumors With Dose Expansion in Triple Negative Breast Cancer
Nippon Kayaku Co., Ltd.
NCT01103310 COMPLETED Radiation Dosimetry, Metabolism, Pharmacokinetics, Safety and Tolerability and PET Imaging With BAY94-9392 in Healthy Volunteers and Patients With Cancer or Inflammation
Life Molecular Imaging SA
NCT01158274 COMPLETED RO4929097 and Capecitabine in Treating Patients With Refractory Solid Tumors
National Cancer Institute (NCI)
NCT02033148 WITHDRAWN Icotinib Hydrochloride in Treating Patients With Advanced Cancers
Roswell Park Cancer Institute
NCT01088763 TERMINATED Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia
National Cancer Institute (NCI)
NCT00742911 COMPLETED Phase I Study of Disulfiram and Copper Gluconate for the Treatment of Refractory Solid Tumors Involving the Liver
University of Utah
NCT00914914 COMPLETED Safety Study of a Cell Penetrating Peptide (p28) to Treat Solid Tumors That Resist Standard Methods of Treatment
Dr. Tapas K. Das Gupta
NCT01164163 COMPLETED INCB18424 in Treating Young Patients With Relapsed or Refractory Solid Tumor, Leukemia, or Myeloproliferative Disease
Children's Oncology Group
NCT01245205 COMPLETED Akt Inhibitor MK2206 in Combination With Lapatinib Ditosylate in Patients With Advanced or Metastatic Solid Tumors or Breast Cancer
National Cancer Institute (NCI)
NCT02136342 TERMINATED Phase 1 Trial of Chlorogenic Acid in Patients With Advanced Cancer
Chinese Academy of Medical Sciences
NCT01447355 COMPLETED Vitamin D Levels in the Skin of Healthy Subjects After Oral Supplementation
National Cancer Institute (NCI)
NCT01348997 WITHDRAWN E-health Intervention for Cancer Survivors 2.0
Northwestern University
NCT01065623 TERMINATED Clinical Study to Evaluate the Maximum Tolerated Dose of BAY79-4620 Given Every 2 Weeks to Patients With Advanced Solid Tumors
Bayer
NCT01339104 COMPLETED Open Label Regorafenib Study to Evaluate Cardiovascular Safety Parameters, Tolerability, and Anti-tumor Activity
Bayer
NCT01292668 COMPLETED Photodynamic Therapy Using Methyl-5-Aminolevulinate Hydrochloride Cream in Determining Pain Threshold in Patients With Skin Cancer
Roswell Park Cancer Institute
NCT01762410 SUSPENDED Clinical Study of Oral PI3K/mTOR Inhibitor in Patients With Advanced Refractory Solid Tumors
Piramal Enterprises Limited
NCT01779336 SUSPENDED Clinical Study of Oral IGF-1R Inhibitor in Subjects With Advanced Refractory Solid Tumors
Piramal Enterprises Limited
NCT01835184 TERMINATED Cabozantinib-S-Malate and Vemurafenib in Treating Patients With Solid Tumors or Melanoma That is Metastatic or That Cannot Be Removed By Surgery
National Cancer Institute (NCI)
NCT01992341 COMPLETED AMG 386 Drug-Drug Interaction Study With Paclitaxel
Amgen
NCT01183364 COMPLETED A Dose Escalation Study of STA-9090 and Docetaxel in Patients With Solid Tumors
Synta Pharmaceuticals Corp.
NCT00968916 COMPLETED Dose Escalation, Safety and Pharmacokinetic Study of AVE8062 in Patients With Solid Tumors
Sanofi
NCT01279603 COMPLETED Study of GO-203-2C Given Intravenously in Patients With Advanced Solid Tumors Including Lymphomas
Genus Oncology, LLC
NCT01057355 WITHDRAWN Endoscopic Ethanol Ablation of Communicating Pancreatic Cystic Neoplasms
Mayo Clinic
NCT01046864 COMPLETED Combination of Brivanib With 5-Fluorouracil/Leucovorin (5FU/LV) and 5-Fluorouracil/Leucovorin/Irinotecan (FOLFIRI)
Bristol-Myers Squibb
NCT01905111 COMPLETED A Study of BI 853520 in Japanese and Taiwanese Patients With Various Types of Advanced or Metastatic Cancer
Boehringer Ingelheim
NCT00724100 TERMINATED A Trial of ALB 109564(a) in Subjects With Advanced Solid Tumors
Albany Molecular Research, Inc.
NCT00720148 COMPLETED A Phase I Trial of Bortezomib and Sunitinib
Emory University
NCT01392976 COMPLETED Safety and Pharmacokinetic Profiles of Two Formulations of CO-1.01 in Patients With Advanced Solid Tumors
Clovis Oncology, Inc.
NCT01313065 COMPLETED Evaluation of Safety, Tolerability, PK & PD of Intravenous VX15/2503 in Patients With Advanced Solid Tumors
Vaccinex Inc.
NCT00927823 COMPLETED A Trial To Assess Safety And Tolerability Of PF-04691502 In Cancer Patients
Pfizer
NCT01215864 COMPLETED Study of Intravenous TCD-717 in Patients With Advanced Solid Tumors
Traslational Cancer Drugs Pharma, SL
NCT00710125 COMPLETED Safety Study of GPX-150 in Patients With Solid Tumors
Gem Pharmaceuticals
NCT01191216 COMPLETED 1-Methyl-D-Tryptophan and Docetaxel in Treating Patients With Metastatic Solid Tumors
National Cancer Institute (NCI)
NCT00847054 COMPLETED A Study of of MORAb-004 in Subjects With Solid Tumors
Morphotek
NCT00621725 COMPLETED Phase 1 PK Study of Cediranib in Single and Multiple Doses in Hepatically Impaired Patients With Solid Tumours
AstraZeneca
NCT01693991 COMPLETED Randomized Controlled Trial of the Meaning-Making Intervention (MMi)
Jewish General Hospital
NCT01003158 COMPLETED Study Assessing Safety and Tolerability of AZD8931 Alone or in Combination With Paclitaxel in Japanese Patients.
AstraZeneca
NCT00759928 COMPLETED PK Trial of Sorafenib & Erlotinib in Patients With Refractory Solid Tumors
SCRI Development Innovations, LLC
NCT01722825 COMPLETED Study of LY2157299 in Japanese Participants With Cancer
Eli Lilly and Company
NCT01222546 COMPLETED Study of CH5132799 Administered Orally in Patients With Advanced Solid Tumors
Chugai Pharma Europe Ltd.
NCT01664273 TERMINATED Gene Electrotransfer to Muscle With Plasmid AMEP in Patients With Disseminated Cancer
Copenhagen University Hospital at Herlev
NCT00609141 COMPLETED IMC-A12 in Treating Young Patients With Relapsed or Refractory Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor or Other Solid Tumor
National Cancer Institute (NCI)
NCT01005355 COMPLETED Study of IMC-1121B in Patients With Advanced Solid Tumors
Eli Lilly and Company
NCT01436565 COMPLETED A Study of Investigational SAR256212 in Combination With SAR245408 in Patients With Solid Tumor Cancers
Sanofi
NCT01401504 COMPLETED Study of an Investigational Drug, ASP3026, in Patients With Solid Tumors
Astellas Pharma Inc
NCT00906698 COMPLETED Afatinib and Vinorelbine in Tumours Known to Overexpress EGFR and/or HER2
Boehringer Ingelheim
NCT01169675 COMPLETED BIBW 2992 (Afatinib) in Combination With Pemetrexed in Advanced Solid Tumours
Boehringer Ingelheim
NCT00729833 TERMINATED Study Of CP-751,871 In Combination With Sunitinib In Patients With Advanced Solid Tumors
Pfizer
NCT00934882 COMPLETED Study to Determine Safety, Pharmacokinetics, Pharmacodynamics of BAY73-4506 in Combination With mFOLFOX6 or FOLFIRI
Bayer
NCT01198184 COMPLETED Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 and Temsirolimus in Treating Patients With Advanced Solid Tumors
National Cancer Institute (NCI)
NCT01217450 COMPLETED Selumetinib and Cetuximab in Treating Patients With Refractory Solid Tumors
National Cancer Institute (NCI)
NCT01957280 COMPLETED Study to Assess Pharmacokinetics, Immunogenicity and Safety/Tolerability of Patritumab (U3-1287)
Daiichi Sankyo
NCT01240538 COMPLETED Viral Therapy in Treating Young Patients With Relapsed or Refractory Solid Tumors
National Cancer Institute (NCI)
NCT01018836 TERMINATED Riluzole and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases
Rutgers, The State University of New Jersey
NCT00933985 TERMINATED Obatoclax Mesylate, Vincristine Sulfate, Doxorubicin Hydrochloride, and Dexrazoxane Hydrochloride in Treating Young Patients With Relapsed or Refractory Solid Tumors, Lymphoma, or Leukemia
National Cancer Institute (NCI)
NCT01231919 COMPLETED MK2206 in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Leukemia
National Cancer Institute (NCI)
NCT00880282 COMPLETED Cixutumumab and Temsirolimus in Treating Younger Patients With Solid Tumors That Have Recurred or Not Responded to Treatment
National Cancer Institute (NCI)
NCT01235897 COMPLETED MK-2206, Paclitaxel and Trastuzumab in Treating Patients With HER2-overexpressing Solid Tumor Malignancies
University of California, San Francisco
NCT01141244 COMPLETED Temsirolimus, Irinotecan Hydrochloride, and Temozolomide in Treating Younger Patients With Relapsed or Refractory Solid Tumors
National Cancer Institute (NCI)
NCT01725555 COMPLETED A Study to Assess the Effect of Food on the Bioavailability of the IGF-1R Inhibitor AXL1717 in Patients With Advanced Malignant Tumors
Axelar AB
NCT01491594 TERMINATED Eltrombopag for the Prevention of Chemotherapy Induced Thrombocytopenia
Duke University
NCT01096355 COMPLETED Gamma-Secretase Inhibitor RO4929097 in Treating Patients With Metastatic or Unresectable Solid Malignancies
National Cancer Institute (NCI)
NCT01243359 COMPLETED Sunitinib Malate and Bevacizumab in Treating Patients With Kidney Cancer or Advanced Solid Malignancies
National Cancer Institute (NCI)
NCT01233505 TERMINATED Veliparib, Oxaliplatin, and Capecitabine in Treating Patients With Advanced Solid Tumors
National Cancer Institute (NCI)
NCT00884845 COMPLETED Trial of PM02734 Administered in Combination With Erlotinib in Patients With Advanced Malignant Solid Tumors
PharmaMar
NCT00942799 COMPLETED Dose Escalation Study to Assess the Safety and Tolerability of Genz-644282 in Patients With Solid Tumors
Genzyme, a Sanofi Company
NCT01114802 COMPLETED E-health Intervention for Cancer Survivors
Northwestern University
NCT00890747 COMPLETED Sunitinib Malate in Treating HIV-Positive Patients With Cancer Receiving Antiretroviral Therapy
National Cancer Institute (NCI)
NCT01641575 TERMINATED A Dose Ascending Study of Gemcitabine Elaidate (CO-101) in Combination With Cisplatin
Clovis Oncology, Inc.
NCT00601614 WITHDRAWN Vandetanib and Temozolomide in Treating Patients With Advanced Solid Tumors That Cannot Be Removed By Surgery
Mayo Clinic
NCT00666991 COMPLETED Pharmacokinetic, Safety and Efficacy Study of Nanoparticle Paclitaxel in Patients With Peritoneal Cancers
CritiTech, Inc.
NCT01455571 COMPLETED Phase I Study to Determine the Maximum Tolerated Dose and to Assess the Safety and Pharmacokinetic Profile of HM781-36B in Patients With Advanced Solid Tumors
Hanmi Pharmaceutical Company Limited
NCT01364844 COMPLETED Safety and Tolerability of DS-7423 in Subjects With Advanced Solid Malignant Tumors
Daiichi Sankyo
NCT00622414 COMPLETED Aflibercept in Treating Young Patients With Relapsed or Refractory Solid Tumors
National Cancer Institute (NCI)
NCT00701298 TERMINATED Decitabine With or Without Interferon Alfa-2b in Treating Patients With Unresectable or Metastatic Solid Tumors
National Cancer Institute (NCI)
NCT01145456 COMPLETED Gamma-Secretase Inhibitor RO4929097 and Gemcitabine Hydrochloride in Treating Patients With Advanced Solid Tumors
National Cancer Institute (NCI)
NCT01012102 COMPLETED EMD 640 744 in Montanide ISA 51 VG Administered in Subjects With Advanced Solid Tumors
Merck KGaA, Darmstadt, Germany
NCT00804076 COMPLETED Gene Transfer for Cancer Pain
Diamyd Inc
NCT01428141 COMPLETED A Phase I Study of E7050 in Subjects With Solid Tumors
Eisai Co., Ltd.
NCT01050985 COMPLETED A Study of Temsirolimus Plus Capecitabine in Patients With Advanced Cancer
Georgetown University
NCT01168752 COMPLETED Study of Debio 0932 in Patients With Advanced Solid Tumours or Lymphoma
Debiopharm International SA
NCT01273090 COMPLETED Imetelstat Sodium in Treating Young Patients With Refractory or Recurrent Solid Tumors or Lymphoma
Children's Oncology Group
NCT01660360 COMPLETED Phase I Trial of Tanibirumab in Advanced or Metastatic Cancer
PharmAbcine
NCT00978523 COMPLETED Study of AR-12 (2-Amino-N-[4-[5-(2 Phenanthrenyl)-3-(Trifluoromethyl)-1H-pyrazol-1-yl] Phenyl]-Acetamide) in Adult Patients With Advanced or Recurrent Solid Tumors or Lymphoma
Arno Therapeutics
NCT01170897 COMPLETED Study of PEGPH20 With Initial Dexamethasone Premedication Given Intravenously to Patients With Advanced Solid Tumors
Halozyme Therapeutics
NCT01306630 COMPLETED A Trial of Tivozanib (AV-951) in Combination With Capecitabine (Xeloda®) in Subjects With Advanced Solid Tumors
AVEO Pharmaceuticals, Inc.
NCT01354041 COMPLETED Fear of Recurrence Pilot Intervention for Women With Breast Cancer
University of California, San Francisco
NCT00725634 COMPLETED A Phase 1 Dose-Escalation Study in Advanced Solid Tumors, Lymphomas or Multiple Myeloma
AVEO Pharmaceuticals, Inc.
NCT00827177 COMPLETED Dose Escalation Study of ARQ 197 in Combination With Sorafenib in Adult Patients With Advanced Solid Tumors
ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA)
NCT02043756 COMPLETED Phase I and Pharmacokinetic Study of Mitoxantrone Hydrochloride Liposome Injection
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
NCT00667485 COMPLETED Rapamycin Plus Bevacizumab in Advanced Cancers
University of Chicago
NCT01423903 COMPLETED Phase 1, Open-label Trial to Determine Safety of OPB-51602 in Subjects With Advanced Cancer
Otsuka Pharmaceutical Development & Commercialization, Inc.
NCT00769288 COMPLETED FAU in Treating Patients With Advanced Solid Tumors or Lymphoma
National Cancer Institute (NCI)
NCT00976508 TERMINATED Figitumumab Combined With Pegvisomant For Advanced Solid Tumors
Pfizer
NCT01728480 WITHDRAWN Entolimod in Treating Patients With Stage III-IV Squamous Cell Head and Neck Cancer Receiving Cisplatin and Radiation Therapy
Roswell Park Cancer Institute
NCT00842244 COMPLETED Study Of Axitinib In Combination With Cisplatin And Capecitabine In Patients With Advanced Gastric Cancer
Pfizer
NCT01496534 TERMINATED Phase Ib Study of Gemcitabine Plus Cisplatin or Carboplatin Plus Dovitinib in Patients With Advanced Solid Tumors
Matthew Galsky
NCT00949026 WITHDRAWN Assessment of Systemically Administered Torisel Delivery to Brain Tumors by Intratumoral Microdialysis
Emory University
NCT00756223 COMPLETED Phase I Study of BI 831266 in Patients With Advanced Solid Tumours
Boehringer Ingelheim
NCT01567384 WITHDRAWN A Phase I Study of OSI-906 in Combination With Pemetrexed in Advanced Solid Tumor Malignancies
Emory University
NCT01409018 COMPLETED Pharmacokinetics of Itraconazole in Pediatric Cancer Patients
Seoul National University Hospital
NCT01096030 COMPLETED Phase I Study of BAY73-4506 in Chinese Patients With Advanced, Refractory Solid Tumors
Bayer
NCT00927966 COMPLETED RAD001 in Combination With CP-751,871 in Patients Wtih Advanced Sarcomas and Other Malignant Neoplasms
Suzanne George, MD
NCT01714765 COMPLETED Dose Escalation Study Investigating Everolimus and Dovitinib in Metastatic Clear Cell Renal Cancer
Queen Mary University of London
NCT00708006 COMPLETED A Study of HGS1029 (AEG40826-2HCl) in Subjects With Advanced Solid Tumors
Human Genome Sciences Inc.
NCT01110486 COMPLETED ABT-348 as Monotherapy or Combination With Carboplatin or Docetaxel to Treat Advanced Solid Tumors
AbbVie (prior sponsor, Abbott)
NCT00689065 TERMINATED Safety Study of CALAA-01 to Treat Solid Tumor Cancers
Calando Pharmaceuticals
NCT01110083 TERMINATED First-in-Man, Dose-escalation Trial of c-Met Kinase Inhibitor EMD 1204831 in Subjects With Advanced Solid Tumors
EMD Serono
NCT01095302 COMPLETED Dose Escalation, Safety and Pharmacokinetic Study of AVE8062 Combined With Docetaxel and Cisplatin in Patients With Solid Tumors
Sanofi
NCT00929903 COMPLETED Pazopanib Hydrochloride in Treating Young Patients With Solid Tumors That Have Relapsed or Not Responded to Treatment
National Cancer Institute (NCI)
NCT01161836 COMPLETED An Open-label Study Investigating the Disposition and QT/QTc Interval Effects of 400 mg [14C]-Iniparib(3.7 MBq, 100 µCi)
Sanofi
NCT01000376 COMPLETED Evaluating the Pharmacokinetics and Tolerance of Co-administration of Oral Multiple Dose of Ketoconazole and an IV (Bolus) Infusion of Eribulin in Patients With Advanced Solid Tumors
Eisai Limited
NCT01159301 TERMINATED Entinostat and Sorafenib Tosylate in Treating Patients With Advanced or Metastatic Solid Tumors or Refractory or Relapsed Acute Myeloid Leukemia
National Cancer Institute (NCI)
NCT01291407 COMPLETED A Phase I Study of S-1 in Combination With Radiotherapy in Locally Advanced or Recurrent Gastric Cancer
Chinese Academy of Medical Sciences
NCT00674947 COMPLETED A Phase I Study of BIIB015 in Relapsed/Refractory Solid Tumors
Biogen
NCT01017198 COMPLETED Effect of Food and Antacid on BIIB021 With Advanced Solid Tumors
Biogen
NCT00721669 COMPLETED A Phase I Dose-Escalation Study of IMGN388 in Patients With Solid Tumors
ImmunoGen, Inc.
NCT01332929 COMPLETED Safety Evaluation of a Combination of Brain Radiation Therapy and Bevacizumab (Avastin®) for Treatment of Brain Metastasis
Centre Francois Baclesse
NCT01618253 WITHDRAWN Radiation Therapy With Sorafenib for TACE-Resistant Hepatocellular Carcinoma
Medical College of Wisconsin
NCT01166490 COMPLETED A Phase 1 Dose Escalation Trial of ASG-5ME in Pancreatic or Gastric Adenocarcinoma
Seagen Inc.
NCT01212341 COMPLETED Allogeneic Natural Killer (NK) Cell Therapy in Patients With Lymphoma or Solid Tumor
Seoul National University Hospital
NCT00569036 COMPLETED Multiple Dose Study In Cancer Patients: Safety and Tolerability of BMS-754807 in Advanced or Metastatic Solid Tumors
Bristol-Myers Squibb
NCT00935961 COMPLETED RAD001 (Everolimus) + Docetaxel + Cisplatin as Induction Chemotherapy in Patients With Local-Regional Advanced Head and Neck Cancer
Memorial Sloan Kettering Cancer Center
NCT01297530 TERMINATED Clinical Study to Evaluate the Maximum Tolerated Dose of BAY87-2243 in Patients With Advanced Malignancies
Bayer
NCT00749502 COMPLETED A Study of MK4827 in Participants With Advanced Solid Tumors or Hematologic Malignancies (MK-4827-001 AM8)
Tesaro, Inc.
NCT00869388 COMPLETED A Phase I Study of Bi-Weekly rBBX-01 in Patients With Solid Tumors
Washington University School of Medicine
NCT01079286 COMPLETED Study of Nelfinavir and Temsirolimus in Patients With Advanced Cancers
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
NCT01451008 COMPLETED Compression Anastomosis Using the Compression Anastomotic Ring-locking Procedure (CARP)
Region Skane
NCT01320020 TERMINATED A Open Label, Dose Escalating Study to Evaluate the Safety and Tolerability of Ascending Intravenous (i.v.) Doses of Catumaxomab in Epithelial Cancer Patients
Neovii Biotech
NCT00906360 TERMINATED Sunitinib, Cetuximab, and Radiation Therapy in Treating Patients With Locally Advanced or Recurrent Squamous Cell Carcinoma of the Head and Neck
National Cancer Institute (NCI)
NCT01282333 TERMINATED Veliparib, Cisplatin, and Gemcitabine Hydrochloride in Treating Patients With Advanced Biliary, Pancreatic, Urothelial, or Non-Small Cell Lung Cancer
National Cancer Institute (NCI)
NCT00994500 COMPLETED Vorinostat and Bortezomib in Treating Young Patients With Refractory or Recurrent Solid Tumors, Including Central Nervous System Tumors and Lymphoma
National Cancer Institute (NCI)
NCT01476085 TERMINATED Evaluating the Utility of the Apoptosis Imaging Biomarker 18F]ML10 in Patients With Non-Hodgkin's Lymphoma(NHL)
GlaxoSmithKline
NCT01401868 COMPLETED Phase I Dose Escalation Study of the Safety and Pharmacokinetics of ME-143 Single Agent for Refractory Solid Tumors
MEI Pharma, Inc.
NCT00909402 COMPLETED A Study of BMS-833923 With Cisplatin and Capecitabine in Inoperable, Metastatic Gastric, Gastroesophageal, or Esophageal Adenocarcinomas
Bristol-Myers Squibb
NCT00732082 TERMINATED Lag-3 and Gemcitabine for Treatment of Advanced Pancreas Cancer
Washington University School of Medicine
NCT01313598 COMPLETED GLPG0187: Safety, Tolerability and Pharmacokinetics in Patients With Solid Tumors
Galapagos NV
NCT01228760 COMPLETED A Study to Determine the Maximum Tolerated Dose of ASG-5ME in Subjects With Castration-Resistant Prostate Cancer
Astellas Pharma Inc
NCT01413906 COMPLETED Phase 1 Multiple Ascending Dose Study of BMS-833923 (XL139) in Subjects With Solid Tumors
Bristol-Myers Squibb
NCT00659568 COMPLETED Metformin and Temsirolimus in Treating Patients With Metastatic or Unresectable Solid Tumor or Lymphoma
London Health Sciences Centre
NCT01213381 COMPLETED Safety and Pharmacokinetics of SAR240550 (BSI-201) Twice Weekly in Patients With Advanced Solid Tumors
Sanofi
NCT00925743 COMPLETED A Study to Evaluate the Effects of Combining Cabazitaxel With Cisplatin Given Every 3 Weeks in Patients With Advanced Solid Cancer
Sanofi
NCT01335256 COMPLETED Clinical Study to Evaluate Safety and Maximum Tolerated Dose of BAY1000394 Given in a 4 Week on / 2 Week Off Schedule in Subjects With Advanced Malignancies
Bayer
NCT01225536 COMPLETED Dose Escalation Study of ARQ 736 in Adult Subjects With Advanced Solid Tumors Harboring BRAF and/or NRAS Mutations
ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA)
NCT01118611 COMPLETED Aurora B/C Kinase Inhibitor GSK1070916A in Treating Patients With Advanced Solid Tumors
Cancer Research UK
NCT00996515 COMPLETED A Phase 1 Protocol of 5-Azacytidine and Erlotinib in Advanced Solid Tumor Malignancies
New Mexico Cancer Research Alliance
NCT00698243 COMPLETED Study of Oral OSI-027 in Patients With Advanced Solid Tumors or Lymphoma
Astellas Pharma Inc
NCT01017939 COMPLETED A Drug-Drug Interaction Study of Abiraterone Acetate Plus Prednisone With Dextromethorphan and Theophylline in Patients With Metastatic Castration-Resistant Prostate Cancer
Janssen Research & Development, LLC
NCT00910754 COMPLETED A QT/QTc and Multi-Dose Pharmacokinetic Study of Abiraterone Acetate Plus Prednisone in Patients With Metastatic Castration-Resistant Prostate Cancer
Janssen Research & Development, LLC
NCT00756847 COMPLETED Safety Study of XL147 (SAR245408), in Combination With Paclitaxel and Carboplatin in Adults With Solid Tumors
Sanofi
NCT00938574 COMPLETED Study With Atu027 in Patients With Advanced Solid Cancer
Silence Therapeutics GmbH
NCT00842452 COMPLETED Topotecan in Treating Patients With Gynecologic Cancer That Cannot Be Removed by Surgery
Steven Waggoner, MD
NCT01611623 COMPLETED Safety and Pharmacology Study of SNX-5422 in Subjects With Refractory Solid Tumor Malignancies
Esanex Inc.
NCT00834704 COMPLETED Safety Study of PEGPH20 Given to Patients With Advanced Solid Tumors
Halozyme Therapeutics
NCT00996957 COMPLETED Study of ACE-041 in Patients With Advanced Solid Tumors or Relapsed/Refractory Multiple Myeloma
Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ USA
NCT00719524 COMPLETED AVE8062 in Combination With Platinum-taxane Doublet in Advanced Solid Tumor
Sanofi
NCT00651365 TERMINATED A Safety and Dose-finding Study of JNJ-38877605 in Patients With Advanced or Refractory Solid Tumors.
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
NCT00937482 TERMINATED Cediranib Maleate and Whole Brain Radiation Therapy in Patients With Brain Metastases From Non-Small Cell Lung Cancer
National Cancer Institute (NCI)
NCT00816686 TERMINATED A Phase 1 Study of the Safety and Pharmacokinetics of AGS-16M18 in Subjects With Advanced Renal Cell Cancer
Astellas Pharma Inc
NCT00816764 COMPLETED A Phase 1 Study of the Safety and Pharmacokinetics of AGS-8M4 in Subjects With Advanced Ovarian Cancer
Astellas Pharma Inc
NCT01016054 TERMINATED A Study of the Safety and Pharmacokinetics of AGS-8M4 Given in Combination With Chemotherapy in Women With Ovarian Cancer
Astellas Pharma Inc
NCT00770731 COMPLETED Study of Temsirolimus, Topotecan, and Bortezomib
M.D. Anderson Cancer Center
NCT00955812 COMPLETED STAT3 Inhibitor for Solid Tumors
M.D. Anderson Cancer Center
NCT01058616 COMPLETED Dose-escalation Study of LTX-315 in Patients With a Transdermally Accessible Tumour
Lytix Biopharma AS
NCT01602627 TERMINATED Hsp90 Inhibitor AUY922 in Treating Older Patients With Advanced Solid Malignancies
Dale Shepard, MD, PhD
NCT01358019 COMPLETED A Study of LY2523355 in Patients With Solid Cancer
Kyowa Kirin Co., Ltd.
NCT00935142 WITHDRAWN Non-invasive Imaging With [18F]VM4-037
Maastricht Radiation Oncology
NCT00555620 COMPLETED Study Of Sunitinib In Combination With Cisplatin/Capecitabine Or Oxaliplatin/Capecitabine In Patients With Advanced Gastric Cancer
Pfizer
NCT01472003 COMPLETED An Evaluation of the Biodistribution and Imaging Characteristics of ABT-806i (111In-ABT-806) in Subjects With Advanced Solid Tumor Types
AbbVie (prior sponsor, Abbott)
NCT00891072 COMPLETED Gossypol, Paclitaxel, and Carboplatin in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery
National Cancer Institute (NCI)
NCT01055795 COMPLETED Safety Study of Bevacizumab, Everolimus and LBH589 (BEL) for Advanced Solid Tumors
Herbert Hurwitz
NCT00849550 COMPLETED Safety and Dosage Study of RAD001 (Everolimus) in Combination With Current Standard of Care to Treat Advanced Solid Tumors.
Herbert Hurwitz
NCT01416623 TERMINATED A Phase I Study of Henatinib in Patients With Advanced Solid Malignancies
Jiangsu HengRui Medicine Co., Ltd.
NCT01336582 COMPLETED Pharmacokinetic Study of SYP-0704A and Taxotere to Treat Patient With Advanced Solid Cancer
Samyang Biopharmaceuticals Corporation
NCT00772876 COMPLETED A Multicenter Phase I Clinical Study of a New Compound P1446A-05 in Patients With Advanced Refractory Malignancies
Piramal Enterprises Limited
NCT01568632 WITHDRAWN Imetelstat for Children With Refractory or Recurrent Solid Tumors and Lymphoma
National Cancer Institute (NCI)
NCT00840190 COMPLETED A Study Of Selective Cyclin Dependent Kinase Inhibitor P1446A-05 In Subjects With Advanced Refractory Malignancies
Piramal Enterprises Limited
NCT00921661 COMPLETED Study of Intravenous Aflibercept in Combination With FOLFIRI in Japanese Patients With Metastatic Colorectal Cancer
Sanofi
NCT01604863 SUSPENDED A Study of HGS1036 in Combination With Chemotherapy in Subjects With Advanced Solid Malignancies
Human Genome Sciences Inc., a GSK Company
NCT00752011 COMPLETED Phase I Study of TAS-106 in Combo With Carboplatin
M.D. Anderson Cancer Center
NCT01158079 COMPLETED Multi-center, Open Label, Extension Study of ALN-VSP02 in Cancer Patients Who Have Responded to ALN-VSP02 Treatment
Alnylam Pharmaceuticals
NCT01161186 COMPLETED Nab-paclitaxel (Abraxane), Gemcitabine, and Capecitabine (Xeloda) for Pancreatic Adenocarcinoma
University of California, San Francisco
NCT00738335 WITHDRAWN Stereotactic Radiosurgery and Erlotinib in Treating Patients With Non-Small Cell Lung Cancer and Brain Metastases
University of California, San Francisco
NCT01286974 TERMINATED A Pharmacokinetic Study to Access How the Body Absorbs and Removes Linifanib in Male Patients With Advanced Solid Tumors.
Abbott
NCT00609921 COMPLETED A Phase 1 Study of ARQ 197 in Patients With Solid Tumors
Kyowa Kirin Co., Ltd.
NCT01016327 TERMINATED Study of NMS-1116354 in Solid Tumors
Nerviano Medical Sciences
NCT01092052 TERMINATED Study of NMS-1116354 in Advanced/Metastatic Solid Tumors
Nerviano Medical Sciences
NCT01014429 COMPLETED Study of NMS-1286937 in Adult Patients With Advanced/Metastatic Solid Tumors
Nerviano Medical Sciences
NCT01041235 COMPLETED Safety Study of a Liposomal Docetaxel Formulation in Patients With Solid Tumors Who Have Failed Previous Therapies
Azaya Therapeutics, Inc.
NCT01521299 WITHDRAWN A Dose Escalation Study of Hydroxyurea in Combination With SCH900776 in Advanced Malignant Solid Tumors
Dartmouth-Hitchcock Medical Center
NCT01506934 TERMINATED A Study Evaluating the Bioavailability of Two Formulations of Linifanib and Food Effect on Pharmacokinetics of Linifanib in Subjects With Advanced or Metastatic Solid Tumors
Abbott
NCT00660153 COMPLETED Study of Tivozanib (AV-951) Plus FOLFOX6 in Subjects With Advanced Colorectal Cancer and Other Gastrointestinal Cancers
AVEO Pharmaceuticals, Inc.
NCT00920595 COMPLETED Study of CEP-9722 as Single-Agent Therapy and as Combination Therapy With Temozolomide in Patients With Advanced Solid Tumors
Cephalon
NCT01294735 COMPLETED Study of the Safety and Efficacy of MK-4827 Given With Temozolomide in Participants With Advanced Cancer (MK-4827-014 AM1)
Merck Sharp & Dohme LLC
NCT00852189 COMPLETED Study of EC0489 for the Treatment of Refractory or Metastatic Tumors
Endocyte
NCT01098838 COMPLETED Safety and Efficacy of LCL161 in Patients With Solid Tumors
Novartis Pharmaceuticals
NCT01042782 COMPLETED Phase I Study of Daily RAD001 in Combination With Mitomycin C in Patients With Advanced Gastric Cancer or Cancer of the Esophagogastric Junction
Krankenhaus Nordwest
NCT01170975 COMPLETED Effects of Food on the Pharmacokinetics of Tesetaxel 10 mg Capsules
Genta Incorporated
NCT00612703 COMPLETED A Phase 1 Study of ARQ 197 in Adult Patients With Advanced Solid Tumors
ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA)
NCT00874042 COMPLETED Dose Escalation Study of ARQ 197 in Combination With Gemcitabine in Adult Patients With Advanced Solid Tumors
ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA)
NCT01139346 COMPLETED Study of Oral Darinaparsin in Patients With Advanced Solid Tumors
Alaunos Therapeutics
NCT00793897 COMPLETED Multiple Dose Study In Cancer Patients: Safety and Tolerability of BMS-754807 in Combination With Paclitaxel and Carboplatin in Patients With Advanced or Metastatic Solid Tumors
Bristol-Myers Squibb
NCT01637194 COMPLETED Cetuximab and Everolimus in Treating Patients With Metastatic or Recurrent Colon Cancer or Head and Neck Cancer
Fox Chase Cancer Center
NCT00731263 COMPLETED A Study of Tor Kinase Inhibitor in Advanced Tumors
AstraZeneca
NCT00999882 COMPLETED Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Efficacy of Tor Kinase Inhibitor in Liver Cancer Patients
AstraZeneca
NCT01226901 TERMINATED A Phase I Study of MK-4827 for Treatment of Solid Tumors (MK-4827-005)
Merck Sharp & Dohme LLC
NCT00706355 TERMINATED A Study of PF-04217903 in Patients With Advanced Cancer
Pfizer
NCT00761696 COMPLETED A Phase 1 Study of IPI-926 in Patients With Advanced and/or Metastatic Solid Tumor Malignancies
Infinity Pharmaceuticals, Inc.
NCT01201018 COMPLETED Evaluation of the Safety and Efficacy of Oshadi D and Oshadi R for Cancer Treatment
Oshadi Drug Administration
NCT01247168 COMPLETED An Open-Label, Dose-Escalation Study of AZD2461
AstraZeneca
NCT01204996 COMPLETED A Study of the Safety and Efficacy of CNTO 888 in Combination With SoC (Standard of Care) Chemotherapy in Patients With Solid Tumors
Centocor, Inc.
NCT00726752 COMPLETED A Study In Patients With Advanced Solid Tumor
Pfizer
NCT00888108 COMPLETED Safety Profile, MTD, and PK Profile Studies of ABT-263 When Administered in Combination With Standard and Weekly Regimens of Docetaxel in Subjects With Cancer
Abbott
NCT00595686 COMPLETED Safety And Pharmacology Of SNX-5422 Mesylate In Subjects With Refractory Hematological Malignancies
Esanex Inc.
NCT00647764 COMPLETED Safety Study Of SNX-5422 To Treat Solid Tumor Cancers And Lymphomas
Esanex Inc.
NCT01599143 COMPLETED Identifying Therapeutic Factors in an 8-Week (30 Hour) Mindfulness-Based Stress Reduction (MBSR) Program
North York General Hospital
NCT01323933 COMPLETED First-in-human Study of AB0024 to Evaluate Safety and Tolerability in Adults With Advanced Solid Tumors
Gilead Sciences
NCT00839631 COMPLETED Dose Escalation Study of EC D-3263 HCl in Advanced Solid Tumors
Dendreon
NCT01147029 TERMINATED GSAO in Treating Patients With Advanced Solid Tumors That Have Not Responded to Therapy
Cancer Research UK
NCT01106248 COMPLETED QT Interval Prolongation Study of Eribulin Mesylate (E7389) in Patients With Advanced Solid Tumors
Eisai Limited
NCT00626158 COMPLETED Gemcitabine and Capecitabine to Treat Patients With Advanced Pancreatic and Biliary Cancers
University of California, San Francisco
NCT00949559 COMPLETED Pharmacodynamics (PD) and Pharmacokinetics (PK) Study of EP-100 in Advanced Solid Tumors
Esperance Pharmaceuticals Inc
NCT01072890 COMPLETED Temsirolimus and Pazopanib in Patients With Advanced Solid Tumors
University of California, Davis
NCT00804310 TERMINATED Lapatinib and Ixabepilone in Treating Patients With Advanced Solid Tumors
University of California, Davis
NCT00706095 COMPLETED Study Of Eribulin (E7389) In Patients With Advanced Solid Tumors And Normal Or Reduced Hepatic Function As Per Child-Pugh System
Eisai Inc.
NCT01381341 COMPLETED To Compare Relative Bioavailability of Two Clinical Formulations of Linifanib.
Abbott
NCT00692640 COMPLETED Safety Study of XL147 (SAR245408) in Combination With Erlotinib in Adults With Solid Tumors
Sanofi
NCT00860860 COMPLETED Study of Pretargeted Radioimmunotherapy of a Anti-CEA Bispecific Antibody and Lu177-labeled Peptide in Colorectal Cancer
Radboud University Medical Center
NCT00734890 COMPLETED Vandetanib and Bevacizumab in Treating Patients With Advanced Solid Tumors or Lymphoma
National Institutes of Health Clinical Center (CC)
NCT00892801 TERMINATED Everolimus and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastasis From Non-Small Cell Lung Cancer
Vanderbilt-Ingram Cancer Center
NCT00908908 COMPLETED A Study to Determine the Metabolism and Elimination of Carbon-14 Labeled Eribulin Acetate (14C-Eribulin) in Patients With Advanced Solid Tumors
Eisai Inc.
NCT01548170 COMPLETED To Assess the Interaction Between Sunitinib and Ketoconazole to Reduce the Dose and Cost of Sunitinib
Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
NCT01146171 WITHDRAWN Japanese Phase 1 Study of BMS-844203 (CT322)
Bristol-Myers Squibb
NCT00777699 COMPLETED Safety Study of XL765 (SAR245409) in Combination With Erlotinib in Adults With Solid Tumors
Sanofi
NCT00661414 COMPLETED Safety Study of ASONEP (Sonepcizumab/LT1009) to Treat Advanced Solid Tumors
Lpath, Inc.
NCT01139788 COMPLETED A Study of LY2624587 in Patients With Advanced Cancer
Eli Lilly and Company
NCT00738764 COMPLETED A Trial of PDL192 in Subjects With Advanced Solid Tumors
Abbott
NCT01028859 COMPLETED Safety Study of Increasing Doses of CKD-516 in Patients With Advanced Solid Cancers
Chong Kun Dang Pharmaceutical
NCT01063946 COMPLETED A Study to Investigate the Disposition of Radio-labeled AVE8062 Compound Administered as a 30-minute IV Infusion to Patients With Advanced Solid Tumor
Sanofi
NCT00555672 COMPLETED Study Of Sunitinib In Combination With Cisplatin And 5-Fluorouracil In Patients With Advanced Gastric Cancer
Pfizer
NCT01087021 COMPLETED Effect of Cabazitaxel on the QTc Interval in Cancer Patients
Sanofi
NCT00935844 COMPLETED Study of TAK-901 in Adults With Advanced Solid Tumors or Lymphoma
Millennium Pharmaceuticals, Inc.
NCT00991770 COMPLETED Massage Therapy and Port-a-Catheter Insertion
Boston Medical Center
NCT00831896 COMPLETED Phase I Study of TAK-701 in Adult Patients With Advanced Nonhematological Malignancies
Millennium Pharmaceuticals, Inc.
NCT00898716 COMPLETED Multiple Ascending Dose Study of BMS-754807 in Patients With Solid Tumors in Japan
Bristol-Myers Squibb
NCT00697879 COMPLETED Safety Study of the Histone Deacetylase Inhibitor, CHR-3996, in Patients With Advanced Solid Tumours
Chroma Therapeutics
NCT00796055 TERMINATED Study of MEDI-547 to Evaluate the Safety, Tolerability, and Biologic Activity of IV Administration in Subjects With Relapsed or Refractory Solid Tumors
MedImmune LLC
NCT01401933 COMPLETED Effect of Rifampin on the Pharmacokinetics of Linifanib in Subjects With Advanced or Metastatic Solid Tumors
Abbott
NCT01141257 COMPLETED Study of Angiocal® in Patients With Solid Tumors, Investigating Safety, Tolerability, Blood Concentration of Study Drug
Pieris Pharmaceuticals GmbH
NCT00920205 COMPLETED Safety Study of MPC-3100 in Cancer Patients Who Have Failed Other Treatments
Myrexis Inc.
NCT00906750 COMPLETED A Study of a Live Intranasal Influenza Vaccine in Children With Cancer
St. Jude Children's Research Hospital
NCT01210846 COMPLETED A Cardiac Safety Study of Tivozanib to Evaluate the Electrocardiogram and Pharmacokinetic-Electrocardiogram Dynamics in Subjects With Advanced Solid Tumors
AVEO Pharmaceuticals, Inc.
NCT00862901 COMPLETED Safety Study Using Photodynamic Therapy Light Therapy for Patients With Chest Wall Progression of Breast Cancer and Satellite Metastases of Melanoma
Tufts Medical Center
NCT01062620 COMPLETED A Dose Escalating Clinical Trial of the IGF-1 Receptor Inhibitor AXL1717 in Patients With Advanced Cancer
Axelar AB
NCT01299415 TERMINATED Safety and Pharmacokinetics of ASA404 When Given Together With Fluvoxamine, a Selective Serotonin Receptor Reuptake Inhibitor and CYP1A2 Inhibitor
Novartis Pharmaceuticals
NCT01290380 TERMINATED A Study to Evaluate the Effects of ASA404 Alone or in Combination With Taxane-based Chemotherapies on the Pharmacokinetics of Drugs in Patients With Advanced Solid Tumor Malignancies
Novartis Pharmaceuticals
NCT00882180 COMPLETED Dose Escalation Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Intravenous ALN-VSP02 In Patients With Advanced Solid Tumors With Liver Involvement
Alnylam Pharmaceuticals
NCT01114191 COMPLETED A Study to Assess the Effect of Ketoconazole on the Pharmacokinetics of Linifanib (ABT-869)
Abbott
NCT00886457 TERMINATED 5-aza-2-deoxycytidine With Pegylated Interferon-alfa 2B: A Phase I Study With Molecular Correlates
Nevada Cancer Institute
NCT01386866 COMPLETED Single Dose Study of [14C]-Labelled AMG 706 in Patients With Advanced Solid Tumors
Amgen
NCT01151384 COMPLETED Liposome Encapsulated Docetaxel (LE-DT) in Patients With Solid Tumors
INSYS Therapeutics Inc
NCT00748891 COMPLETED DCE CT/MRI Scanning Study in Patients With Solid Tumours (AstraZeneca and Royal Marsden Hospital Imaging Study)
AstraZeneca
NCT00783328 COMPLETED A Study Of PF-00299804 In Patients In Japan With Advanced Malignant Solid Tumors
Pfizer
NCT00973076 COMPLETED Study to Assess the Safety and Tolerability of the Tor Kinase Inhibitor AZD8055
AstraZeneca
NCT01021150 COMPLETED Dose Escalation, Safety and Pharmacokinetic Study of AVE8062 Combined With Cisplatin in Patients With Solid Tumors
Sanofi
NCT00788099 COMPLETED Study of Plitidepsin in Combination With Sorafenib or Gemcitabine in Patients With Advanced Solid Tumors or Lymphomas
PharmaMar
NCT00616213 COMPLETED PR104 and G-CSF in Treating Patients With Solid Tumors
Proacta, Incorporated
NCT00704366 COMPLETED AZD0530 Study 21 - Phase I Study in Patients With Solid Tumours
AstraZeneca
NCT00631410 COMPLETED Study Of Sunitinib In Combination With Folfox In Patients With Colorectal Cancer
Pfizer
NCT00750425 COMPLETED Phase 1 Study of the Effect of Ketoconazole on the PK of Multiple Doses of Cediranib in Patients With Solid Tumours
AstraZeneca
NCT00937664 TERMINATED Safety and Tolerability Study of AZD7762 in Combination With Gemcitabine
AstraZeneca
NCT00754104 WITHDRAWN Study of ABT-869 in Combination With Tarceva in Subjects With Solid Tumors
Abbott
NCT01018745 COMPLETED Multiple Ascending Dose Study of BMS-907351 (XL184) in Patients With Solid Tumors in Japan
Bristol-Myers Squibb
NCT01021358 COMPLETED A Study to Assess the Effect of Ketoconazole on the Metabolism of ABT-263 (Navitoclax).
Abbott
NCT00733031 TERMINATED Phase I, Open-label, Dose-escalation, Safety and PK Study of AZD6918
AstraZeneca
NCT01247532 COMPLETED Pilot Study of Mindfulness-Based Stress Reduction for Patients With Persistent Cancer-Related Fatigue
Indiana University
NCT00989443 COMPLETED Safety and Tolerability of Cidofovir Gel Applied on Cervix Squamous Lesions
Mithra Pharmaceuticals
NCT01223924 COMPLETED Single-dose Escalation Trial of M2ES in Healthy Volunteer
Protgen Ltd
NCT00778128 COMPLETED A Phase I Clinical Study of Oral CP-4126 in Patients With Advanced Solid Tumour
Clavis Pharma
NCT00730470 COMPLETED Phase I Study of U3P1287/01, Including Patients With Advanced Solid Tumors
U3 Pharma GmbH
NCT00925275 COMPLETED Dosimetry Study of I-131-CLR1404 in Patients With Relapsed or Refractory Advanced Solid Tumors
Cellectar, Inc
NCT00773929 COMPLETED Safety Study of TAK-593 Given Orally in Subjects With Nonhematologic Advanced Cancer
Millennium Pharmaceuticals, Inc.
NCT01023386 COMPLETED A Clinical Pharmacological Study of YM155 After Intravenous Infusion in Patients With Advanced Cancer
Astellas Pharma Inc
NCT00909558 SUSPENDED Safety and Effectiveness Study of Autologous Natural Killer and Natural Killer T Cells on Cancer
Envita Medical Center, Inc.
NCT01000896 WITHDRAWN Study to Assess Safety and Tolerability of AZD0530 in Combination With Carboplatin and Paclitaxel
AstraZeneca
NCT00886353 COMPLETED Safety and Tolerability Study of APN01 (Recombinant Human Angiotensin Converting Enzyme 2)
Apeiron Biologics
NCT00656461 COMPLETED Phase 1 Study of MKC-1 in Patients With Advanced Cancer
CASI Pharmaceuticals, Inc.
NCT00949793 COMPLETED In Vivo Confocal Endomicroscopy of the Brain
Carl Zeiss Surgical GmbH
NCT00608803 COMPLETED Phase 1 Study of ZIO-201-T in Combination With Doxorubicin in Solid Tumors
Alaunos Therapeutics
NCT00613652 COMPLETED A Phase I, Dose-Escalation Study to Assess the Safety and Drug Levels in Blood of AZD4877 in Japanese Adult Patients
AstraZeneca
NCT00690053 COMPLETED Non-Invasive Imaging of [18F]HX4 With Positron-Emission-Tomography (PET)
Maastricht Radiation Oncology
NCT00664170 COMPLETED A Bioequivalence Study of Docetaxel for Injectable Emulsion (ANX-514) in Patients With Advanced Cancer
Mast Therapeutics, Inc.
NCT00827203 SUSPENDED A Safety Study to Determine the Maximum Tolerated Dose of Elesclomol Sodium in Patients With Solid Tumors
Synta Pharmaceuticals Corp.
NCT00621556 TERMINATED Secretin Enhanced MRCP for Evaluation of the Known or Suspected Intraductal Papillary Mucinous Neoplasms of the Pancreas
Massachusetts General Hospital
NCT00753480 SUSPENDED A Study of D4064A Administered to Patients With Recurrent or Persistent Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
Genentech, Inc.
NCT00578916 COMPLETED Pharmacokinetics and Metabolism of Radiolabeled BMS-690514 in Healthy Male Subjects
Bristol-Myers Squibb
NCT00606879 TERMINATED Safety Study of SGX523, a Small Molecule Met Inhibitor, to Treat Solid Tumors
SGX Pharmaceuticals, Inc.
NCT00607399 TERMINATED Safety Study of SGX523, a Small Molecule Met Inhibitor, to Treat Solid Tumors
SGX Pharmaceuticals, Inc.
NCT00607711 SUSPENDED Study of Oral Palifosfamide Tris in Solid Tumors
Alaunos Therapeutics