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Data updated: May 26, 2026

LOCOID LIPOCREAM (hydrocortisone butyrate)

Immunology Approved 1997-09-08

Locoid Lipocream is a topical corticosteroid used for patients with mild to moderate atopic dermatitis. It helps manage skin symptoms in adults and children as young as three months of age. This cream is applied directly to affected areas to help control the condition.

Source: FDA Label • PRECISION DERMAT

How LOCOID LIPOCREAM Works

This medication works by influencing cellular signaling, immune function, and protein regulation. While the exact process for helping atopic dermatitis is not fully understood, the drug plays a key role in managing inflammation and the body's immune response.

2
Indications
--
Phase 3 Trials
28
Years on Market

Details

Status
Prescription
First Approved
1997-09-08
Routes
TOPICAL
Dosage Forms
CREAM

Companies

Active Ingredient: HYDROCORTISONE BUTYRATE

LOCOID LIPOCREAM Approval History

1998
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Original
New Indication
New Form
Label Update
8 FDA actions from 1997 to 2024 · 1 indication expansions
Oct 2024 SUPPL
Label · Labeling
Nov 2014 SUPPL
Label · Labeling
Oct 2009 SUPPL
Efficacy

What LOCOID LIPOCREAM Treats

1 indications

LOCOID LIPOCREAM is approved for 1 conditions since its original approval in 1997. These indications span multiple therapeutic areas including oncology, immunology, and more.

  • Atopic Dermatitis
Source: FDA Label

LOCOID LIPOCREAM Competitive Set

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Filters applied: drops same-active-ingredient (505(b)(2) reformulations), route-mismatch (topical vs systemic), and cross-therapeutic-area matches in same-indication rings.

What's emerging in LOCOID LIPOCREAM's indications

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Phase 3 candidates targeting molecules with no FDA-approved drug, in indications LOCOID LIPOCREAM treats. First-in-class if their pivotal trials read out positive.

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Active Pipeline

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Key Completed Trials

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Completed studies with published results, ranked by significance

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Trial Timeline

Full development history with FDA approval milestones

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Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

LOCOID LIPOCREAM FDA Label Details

Indications & Usage

FDA Label (PDF)

LOCOID LIPOCREAM is indicated for the treatment of Atopic Dermatitis.

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Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.