TheraRadar
Data updated: May 26, 2026

METHAMPHETAMINE HYDROCHLORIDE

CNS Approved 1976-01-19

Methamphetamine hydrochloride tablets are used for pediatric patients aged 6 years and older who have Attention Deficit Hyperactivity Disorder (ADHD). This central nervous system stimulant helps children manage the symptoms associated with this condition. It is prescribed to provide therapeutic support for young patients diagnosed with ADHD.

Source: FDA Label • Dr. Reddy's

How METHAMPHETAMINE HYDROCHLORIDE Works

This medication works by stimulating the central nervous system. As a non-catecholamine sympathomimetic amine, it produces stimulant activity in the brain, though the specific process by which it improves ADHD symptoms is not yet fully known.

Source: FDA Label
4
Indications
--
Phase 3 Trials
50
Years on Market

Details

Status
Prescription
First Approved
1976-01-19
Routes
ORAL
Dosage Forms
TABLET

METHAMPHETAMINE HYDROCHLORIDE Approval History

1977
1978
1979
1980
1981
1982
1983
1984
1985
1986
1987
1988
1989
1990
1991
1992
1993
1994
1995
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
Original
New Indication
New Form
Label Update
19 FDA actions from 1976 to 2025
Mar 2025 SUPPL
Mfg · Manufacturing (CMC)
Jun 2024 SUPPL
Label · Labeling
Apr 2024 SUPPL
Label · Labeling

What METHAMPHETAMINE HYDROCHLORIDE Treats

1 indications

METHAMPHETAMINE HYDROCHLORIDE is approved for 1 conditions since its original approval in 1976. These indications span multiple therapeutic areas including oncology, immunology, and more.

  • Attention Deficit Hyperactivity Disorder
Source: FDA Label

METHAMPHETAMINE HYDROCHLORIDE Boxed Warning

Methamphetamine has a high potential for abuse and misuse, which can lead to the development of a substance use disorder, including addiction. Misuse and abuse of CNS stimulants, including methamphetamine, can result in overdose and death [see Overdosage ( 10 )] , and this risk is increased with higher doses or unapproved methods of administration, such as snorting or injection. Before prescribing methamphetamine, assess each patient’s risk for abuse, misuse, and addiction. Educate patients and ...

METHAMPHETAMINE HYDROCHLORIDE Competitive Set

Pro

Three rings of competition based on shared molecular targets and treated indications.

Unlock 8 more competitors across all three rings.
Upgrade to Pro

Filters applied: drops same-active-ingredient (505(b)(2) reformulations), route-mismatch (topical vs systemic), and cross-therapeutic-area matches in same-indication rings.

Drugs Similar to METHAMPHETAMINE HYDROCHLORIDE

3 of 20

FDA-approved drugs for similar conditions. Compare mechanisms and indications to understand treatment alternatives.

ADDERALL XR 10
AMPHETAMINE ASPARTATE
1 shared
Takeda
ADDERALL XR 15
AMPHETAMINE ASPARTATE
1 shared
Takeda
ADDERALL XR 20
AMPHETAMINE ASPARTATE
1 shared
Takeda
🔬

Active Pipeline

Pro

Ongoing clinical trials by development phase

Loading...

Key Completed Trials

Pro

Completed studies with published results, ranked by significance

Loading...
📊

Trial Timeline

Full development history with FDA approval milestones

|
Loading...
Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

METHAMPHETAMINE HYDROCHLORIDE FDA Label Details

Indications & Usage

METHAMPHETAMINE HYDROCHLORIDE is indicated for the treatment of Attention Deficit Hyperactivity Disorder.

⚠️ BOXED WARNING

Methamphetamine has a high potential for abuse and misuse, which can lead to the development of a substance use disorder, including addiction. Misuse and abuse of CNS stimulants, including methamphetamine, can result in overdose and death [see Overdosage ( 10 )] , and this risk is increased with hig...

Looking for the branded version?

DESOXYN

Full clinical data, patents, trials, and competitive landscape for methamphetamine hydrochloride.

See DESOXYN

Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.