TheraRadar
Data updated: May 26, 2026

PROLENSA (bromfenac sodium)

Ophthalmology Approved 2013-04-05

Prolensa is a nonsteroidal anti-inflammatory medication used for patients recovering from cataract surgery. It helps manage postoperative inflammation and reduces ocular pain associated with the procedure. By addressing these symptoms, the drug supports the healing process and improves patient comfort following eye surgery.

Source: FDA Label • BAUSCH AND LOMB

How PROLENSA Works

This medication works by blocking the synthesis of prostaglandins, which are known mediators of intraocular inflammation. It achieves this by inhibiting the cyclooxygenase 1 and 2 enzymes. By reducing prostaglandin levels, the drug helps prevent vasodilation, increased vascular permeability, and elevated intraocular pressure in the eye.

1
Indication
--
Phase 3 Trials
13
Years on Market

Details

Status
Prescription
First Approved
2013-04-05
Patent Cliff
2033

Pro Metrics

Patent cliff and revenue data

Unlock with Pro
Routes
OPHTHALMIC
Dosage Forms
SOLUTION/DROPS

Companies

Active Ingredient: BROMFENAC SODIUM

PROLENSA Approval History

2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
Original
New Indication
New Form
Label Update
4 FDA actions from 2013 to 2025
Feb 2025 SUPPL
Label · Labeling
Dec 2015 SUPPL
Mfg · Manufacturing (CMC)
Jul 2015 SUPPL
Mfg · Manufacturing (CMC)

What PROLENSA Treats

2 indications

PROLENSA is approved for 2 conditions since its original approval in 2013. These indications span multiple therapeutic areas including oncology, immunology, and more.

  • Inflammation
  • Ocular Pain
Source: FDA Label

PROLENSA Competitive Set

Pro

Three rings of competition based on shared molecular targets and treated indications.

Unlock 10 more competitors across all three rings.
Upgrade to Pro

Filters applied: drops same-active-ingredient (505(b)(2) reformulations), route-mismatch (topical vs systemic), and cross-therapeutic-area matches in same-indication rings.

Drugs Similar to PROLENSA

3 of 20

FDA-approved drugs for similar conditions. Compare mechanisms and indications to understand treatment alternatives.

BROMFENAC SODIUM
BROMFENAC SODIUM
2 shared
Apotex
Shared indications:
InflammationOcular Pain
BROMSITE
BROMFENAC SODIUM
2 shared
Sun Pharma
Shared indications:
InflammationOcular Pain
ACULAR
KETOROLAC TROMETHAMINE
1 shared
AbbVie
Shared indications:
🔬

Active Pipeline

Pro

Ongoing clinical trials by development phase

Loading...

Key Completed Trials

Pro

Completed studies with published results, ranked by significance

Loading...
📊

Trial Timeline

Full development history with FDA approval milestones

|
Loading...
Understanding FDA Approval Types
Count Type What it means
- ORIG Original approval - drug first enters market
- SUPPL - Efficacy New indication (new disease/condition approved)
- SUPPL - Labeling Label text changes (warnings, dosing updates)
- SUPPL - Manufacturing Production changes (new facility)
- SUPPL - Chemistry Formulation changes (new dosage strength)

Green lines in the timeline show ORIG and Efficacy approvals - the clinically meaningful milestones.

PROLENSA FDA Label Details

Indications & Usage

FDA Label (PDF)

PROLENSA is indicated for the treatment of Inflammation; Ocular Pain.

View full patent landscape →
2 OB patents · 1 families · 22 international docs across 13 countries

PROLENSA Patents & Exclusivity

Latest Patent: Nov 2033

Patents (2 active)

US9517220 Expires Nov 11, 2033
US10085958 Expires Nov 19, 2032
Source: FDA Orange Book

Pro Intelligence Preview

Deep insights for PROLENSA

Revenue Insights

  • Quarterly revenue tracking
  • Historical trend analysis

Patent Timeline

  • Cliff: 2033
  • 2 active patents

Trial Analysis

  • Clinical trial tracking
  • Development stage analysis

Competitive Landscape

  • 20 similar drugs
  • Same target/indication analysis
Unlock Full Intelligence

Full approval history • All patents • Revenue trends • Competitor analysis

Data Sources

Data sourced from official FDA and NIH databases. Click links to verify on original sources.