Achieve Life Sciences
Pre-Approval PRO BETAPipeline by Phase
Therapeutic Focus
Clinical Trials (20)
A Multinational, Randomized, Open-Label Study of Custirsen In Patients With Advanced or Metastatic (Stage IV) Non-Small Cell Lung Cancer
Started: 10/24/2012
Phase 3 Trial Evaluating the Efficacy and Safety of Cytisinicline for Vaping Cessation in Adults Using Nicotine-Containing E Cigarettes
Started: 5/15/2026
A Study of Cytisinicline for Smoking Cessation in Adult Smokers
Started: 10/13/2020
A Second Study of Cytisinicline for Smoking Cessation in Adult Smokers
Started: 1/20/2022
Safety Study of Cytisinicline in Adult Combustible and/or E-cigarette Smokers
Started: 5/28/2024
Comparison of Docetaxel/Prednisone to Docetaxel/Prednisone in Combination With OGX-011 in Men With Prostate Cancer
Started: 11/1/2010
A Study Evaluating the Pain Palliation Benefit of Adding Custirsen to Docetaxel Retreatment or Cabazitaxel as Second Line Therapy in Men With Metastatic Castrate Resistant Prostate Cancer (mCRPC)
Started: 3/1/2010
Comparison of Cabazitaxel/Prednisone Alone or in Combination With Custirsen for 2nd Line Chemotherapy in Prostate Cancer
Started: 8/1/2012
A Study of Cytisinicline for Vaping Cessation in Adult Smokers
Started: 7/13/2022
A Phase 2 Study Comparing Chemotherapy in Combination With OGX-427 or Placebo in Patients With Bladder Cancer
Started: 10/1/2011
Study to Evaluate the Effect of Renal Impairment and Dialysis Treatment on the Pharmacokinetics of a Single 3 mg Cytisinicline Dose
Started: 1/10/2023
Study to Evaluate Effect of Food on Bioavailability of Single 3 mg Tablet and Pharmacokinetics (PK) of Multiple 3 mg Doses in Healthy Adult Smokers
Started: 8/8/2023
Study to Evaluate Electrocardiographic Effects of Therapeutic & Supratherapeutic Doses of Cytisinicline in Healthy Smokers
Started: 10/17/2022
A Single Dose-escalation Study of Cytisine in Adult Smokers
Started: 2/28/2019
A Pharmacokinetic and Pharmacodynamic Evaluation of Cytisine in Healthy Smokers
Started: 10/6/2017
A Study in Healthy Smokers to Investigate the Effect of Food on the Bioavailability of Cytisine in a New Formulation
Started: 4/27/2018
A Study in Healthy Volunteers to Investigate the Effect of Food on the Bioavailability of Cytisine
Started: 8/8/2017
A Clinical Study in Cancer Patients to Investigate the Potential Impact of Custirsen, on the Blood Levels of the Chemotherapeutic Drug, Paclitaxel, When Given Together as Part of a Treatment Regimen
Started: 4/1/2012
Thorough QT/QTc (Corrected QT Interval) Study to Evaluate the Effect of Custirsen on Cardiac Repolarization
Started: 5/1/2013