TheraRadar

Allakos

Pre-Approval PRO BETA
🟡

Slowing Activity

No new clinical trials started in 1-2 years. Monitor for changes in pipeline strategy. Last trial started: 8/28/2024

18
Total Trials
5
Phase 3
7
Phase 2
0
Recruiting
152
Score

Pipeline by Phase

Phase 3
5
Phase 2
7
Phase 1
7

Therapeutic Focus

Eosinophilic Gastritis Eosinophilic Duodenitis Chronic Spontaneous Urticaria Eosinophilic Gastroenteritis Healthy Participants

Clinical Trials (18)

NCT04620811 Phase 3 COMPLETED

An Extension Study of Lirentelimab in Eosinophilic Gastritis and/or Eosinophilic Duodenitis (Formerly Referred to as Eosinophilic Gastroenteritis)

Started: 12/3/2020

NCT04322604 Phase 3 COMPLETED

A Study to Assess AK002 in Eosinophilic Gastritis and/or Eosinophilic Duodenitis (Formerly Referred to as Eosinophilic Gastroenteritis)

Started: 6/18/2020

NCT04856891 Phase 3 COMPLETED

A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Duodenitis

Started: 5/20/2021

NCT05152563 Phase 3 WITHDRAWN

A Study to Assess Subcutaneous AK002 in Eosinophilic Gastritis and/or Eosinophilic Duodenitis

Started: 12/1/2021

NCT05155085 Phase 2 TERMINATED

A Study to Assess Subcutaneous Lirentelimab (AK002) in Atopic Dermatitis

Started: 6/27/2022

NCT05528861 Phase 2 TERMINATED

A Study to Assess Subcutaneous Lirentelimab (AK002) in Chronic Spontaneous Urticaria

Started: 10/26/2022

NCT03436797 Phase 2 COMPLETED

A Study to Assess the Efficacy and Safety of AK002 in Subjects With Antihistamine-Resistant Chronic Urticaria

Started: 1/23/2018

NCT03664960 Phase 2 COMPLETED

An Extension Study of AK002 in Patients With Eosinophilic Gastritis and/or Eosinophilic Duodenitis

Started: 11/14/2018

NCT03496571 Phase 2 COMPLETED

A Study of AK002 in Patients With Eosinophilic Gastritis and/or Eosinophilic Gastroenteritis

Started: 7/18/2018

NCT04322708 Phase 2 COMPLETED

A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Esophagitis

Started: 7/6/2020

NCT02734849 Phase 2 COMPLETED

Study to Evaluate Multiple Doses in Patients With Nasal Polyposis

Started: 4/1/2016

NCT06577116 Phase 1 COMPLETED

Open-Label Extension Study for Subjects With H1 Antihistamine Refractory Chronic Spontaneous Urticaria Completing Study AK006-001

Started: 8/28/2024

NCT06072157 Phase 1 COMPLETED

Study to Assess the Safety, Tolerability, Pharmacokinetics and Immunogenicity of AK006 in Healthy Subjects and Subjects With Chronic Spontaneous Urticaria

Started: 8/28/2023

NCT04324268 Phase 1 COMPLETED

A Study to Evaluate Safety, Tolerability, and Bioavailability of Subcutaneous Lirentelimab (AK002) in Adult Healthy Volunteers

Started: 3/23/2020

NCT03379311 Phase 1 COMPLETED

A Study of AK002 in Patients With Atopic Keratoconjunctivitis, Vernal Keratoconjunctivitis, and Perennial Allergic Conjunctivitis

Started: 2/26/2018

NCT02808793 Phase 1 COMPLETED

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AK002

Started: 6/1/2016

NCT02859701 Phase 1 COMPLETED

Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AK002 in Healthy Participants

Started: 8/1/2016

NCT02563938 Phase 1 COMPLETED

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AK001

Started: 9/1/2015

Drug Candidates

AK006 IV AK006-IV Placebo-IV AK006-SC Placebo-SC AK002 Lirentelimab (AK002) lirentelimab lirentelimab (AK002) AK001 low dose
Activity Status: Slowing
Last Trial Started: 8/28/2024
Last Trial Ended: 5/21/2025
Trials (12 months): 0
Completed Trials: 15
Data sourced from ClinicalTrials.gov. This company has no FDA-approved drugs.