TheraRadar

Allist

Pre-Approval PRO BETA
24
Total Trials
6
Phase 3
8
Phase 2
14
Recruiting
204
Score

Pipeline by Phase

Phase 3
6
Phase 2
8
Phase 1
15

Therapeutic Focus

NSCLC Solid Tumor Non-small Cell Lung Cancer KRAS P.G12C Colorectal Cancer

Clinical Trials (24)

NCT06970639 Phase 3 RECRUITING

A Study Evaluating Furmonertinib Plus Platinum-based Doublet Chemotherapy Versus Osimertinib in Patients With Epidermal Growth Factor Receptor (EGFR) Sensitizing Mutation-Positive Non-squamous Non-Small Cell Lung Cancer (NSCLC) and Brain Metastases

Started: 9/26/2024

NCT06956001 Phase 3 RECRUITING

Firmonertinib Versus Platinum Based Chemotherapy as First-line Treatment for NSCLC With EGFR PACC or EGFR l861q Mutation

Started: 11/19/2024

NCT07010419 Phase 3 RECRUITING

A Study to Assess the Efficacy and Safety of Firmonertinib Versus Placebo for Adjuvant Treatment in Participants With Stage IB - IIIB NSCLC With Uncommon Epidermal Growth Factor Receptor (EGFR) Mutations, Following Complete Surgical Resection With or Without Adjuvant Chemotherapy(FIRMOST)

Started: 5/28/2025

NCT06416410 Phase 3 RECRUITING

JAB-21822 Combined With JAB-3312 Compared SOC in the First Line for Treatment of Advanced Non-small Cell Lung Cancer With KRAS p.G12C Mutation

Started: 8/7/2024

NCT04853342 Phase 3 RECRUITING

To Assess the Efficacy and Safety of Furmonertinib Versus Placebo, in Patients With Epidermal Growth Factor Receptor Mutation Positive Stage II-IIIA Non-small Cell Lung Carcinoma, Following Complete Tumour Resection With or Without Adjuvant Chemotherapy

Started: 6/7/2021

NCT03787992 Phase 3 ACTIVE NOT RECRUITING

Alflutinib Mesylate Versus Gefitinib in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer (FLAG)

Started: 5/30/2019

NCT06008288 Phase 2 RECRUITING

A Phase II Study Evaluating JAB-21822 Monotherapy in Adult Patients With Pancreatic Cancer and Other Solid Tumors Harboring the KRAS p.G12C Mutation.

Started: 10/27/2023

NCT05466149 Phase 2 ACTIVE NOT RECRUITING

Efficacy and Safety of Furmonertinib in Patients With Locally Advanced or Metastatic NSCLC With EGFR Exon 20 Insertion

Started: 9/27/2022

NCT03452592 Phase 2 TERMINATED

Efficacy and Safety of Alflutinib in Locally Advanced or Metastatic Non-Small Cell Lung Cancer Patients With T790M

Started: 4/30/2018

NCT06955988 Phase 1 RECRUITING

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of AST2303 Tablets (ABK3376 Tablets) in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer

Started: 3/4/2025

NCT05288205 Phase 1 RECRUITING

Phase 1/2a Study of JAB-21822 Plus JAB-3312 in Patients With Advanced Solid Tumors Harboring KRAS p.G12C Mutation

Started: 4/14/2022

NCT05276726 Phase 1 RECRUITING

A Study of JAB-21822 in Advanced or Metastatic NSCLC With KRAS p.G12C and STK11 Co-mutation and Wild-type KEAP1

Started: 8/17/2022

NCT05194995 Phase 1 ACTIVE NOT RECRUITING

JAB-21822 in Combination With Cetuximab in Patients With Advanced CRC and Other Solid Tumors With KRAS G12C Mutation

Started: 2/17/2022

NCT05009329 Phase 1 ACTIVE NOT RECRUITING

A Study of JAB-21822 in Adult Patients With Advanced Solid Tumors Harboring KRAS p.G12C Mutation in China

Started: 7/26/2021

NCT04858958 Phase 1 ACTIVE NOT RECRUITING

Study of FURMONERTINIB in Patients With NSCLC Having Exon 20 Insertion Mutation

Started: 8/10/2020

NCT04121286 Phase 1 COMPLETED

A Study of JAB-3312 in Adult Patients With Advanced Solid Tumors in China

Started: 7/14/2020

NCT04720976 Phase 1 COMPLETED

JAB-3312 Based Combination Therapy in Adult Patients With Advanced Solid Tumors

Started: 3/23/2021

NCT06162169 Phase 1 COMPLETED

A Clinical Trial to Evaluate JAB-21822 Drug-drug Interactions in Healthy Subjects

Started: 11/25/2023

NCT05920941 Phase 1 COMPLETED

Mass Balance Study of [14C]JAB-21822

Started: 7/8/2023

NCT05875493 Phase 1 COMPLETED

A Food Effect Study of JAB-21822 in Healthy Subjects

Started: 5/12/2023

NCT02973763 Phase 1 TERMINATED

Safety, Tolerability, Pharmacokinetics and Anti-tumour Activity of Alflutinib in Advanced Non Small Cell Lung Cancer

Started: 12/30/2016

NCT04958967 Phase 1 WITHDRAWN

Phase Ib Study of FURMONERTINIB in Patients with NSCLC Having Exon 20 Insertion Mutation

Started: 10/1/2021

NCT03926182 Phase 1 COMPLETED

Study to Determine the Effect of Food on the Blood Levels of AST2818 Following Single Oral Doses in Healthy Male Volunteers

Started: 2/19/2019

NCT03941340 Phase 1 COMPLETED

Study Evaluating the Mass Balance And Biotransformation of Single Dose[14C] AST2818 in Chinese Healthy Male Volunteers

Started: 4/8/2019

Drug Candidates

JAB-21822 Cetuximab Furmonertinib Mesilate Tablets Carboplatin Injection Cisplatin for injection Pemetrexed Disodium for Injection Osimertinib Mesylate Tablets AST2303 Tablets(ABK3376 Tablets) ,25mg AST2303 Tablets(ABK3376 Tablets) ,50mg AST2303 Tablets(ABK3376 Tablets) ,75mg
Activity Status: Active
Last Trial Started: 5/28/2025
Last Trial Ended: 3/14/2024
Trials (12 months): 1
Completed Trials: 7
Data sourced from ClinicalTrials.gov. This company has no FDA-approved drugs.