TheraRadar

Alumis

Pre-Approval PRO BETA
🟡

Slowing Activity

No new clinical trials started in 1-2 years. Monitor for changes in pipeline strategy. Last trial started: 4/29/2025

13
Total Trials
3
Phase 3
4
Phase 2
4
Recruiting
95
Score

Pipeline by Phase

Phase 3
3
Phase 2
4
Phase 1
6

Therapeutic Focus

Plaque Psoriasis Healthy Volunteer Psoriasis (PsO) Psoriasis Moderate Psoriasis

Clinical Trials (13)

NCT06846541 Phase 3 ACTIVE NOT RECRUITING

Long-term Safety and Efficacy of ESK-001 in Moderate to Severe Plaque Psoriasis

Started: 1/8/2025

NCT06588738 Phase 3 COMPLETED

A Study in Patients With Moderate to Severe Plaque Psoriasis to Evaluate the Efficacy and Safety of ESK-001

Started: 8/20/2024

NCT06586112 Phase 3 COMPLETED

A Study to Evaluate the Efficacy and Safety of ESK-001 in Patients With Moderate to Severe Plaque Psoriasis

Started: 7/25/2024

NCT05966480 Phase 2 ACTIVE NOT RECRUITING

Phase 2 Placebo-Controlled Study to Assess the Safety and Efficacy of ESK-001 in Active Systemic Lupus Erythematosus

Started: 6/26/2023

NCT05739435 Phase 2 ACTIVE NOT RECRUITING

Open-Label Extension Study to Evaluate the Long Term Safety and Efficacy of ESK-001 in Plaque Psoriasis

Started: 1/17/2023

NCT05600036 Phase 2 COMPLETED

A Study to Evaluate the Efficacy and Safety of ESK-001 in Patients With Plaque Psoriasis

Started: 9/27/2022

NCT05953688 Phase 2 TERMINATED

POC Study to Evaluate the Efficacy and Safety of ESK-001 in Patients With Active Intermediate, Posterior, or Pan NIU

Started: 6/14/2023

NCT06952634 Phase 1 RECRUITING

An Investigational Study of ESK-001 in Participants With Normal Liver Function and Participants With Mild, Moderate, and Severe Liver Damage

Started: 4/29/2025

NCT07442149 Phase 1 COMPLETED

An Investigational Study to Evaluate the Safety and Tolerability of Single and Multiple Ascending Doses of A-005

Started: 4/22/2024

NCT07378579 Phase 1 COMPLETED

An Investigational Study to Evaluate the Cardiac Safety Assessment (TQTc Study) of ESK-001

Started: 6/21/2024

NCT06962774 Phase 1 COMPLETED

An Investigational Study of ESK-001 in Participants With Normal Renal Function and Participants With Mild, Moderate, and Severe Impaired Renal Function

Started: 4/23/2025

NCT05431634 Phase 1 COMPLETED

Multiple Dose Study to Determine Safety and Tolerability of ESK-001 in Healthy Participants

Started: 5/12/2022

NCT05330858 Phase 1 COMPLETED

Relative Bioavailability of ESK-001 Tablet Versus Liquid in Healthy Participants

Started: 3/17/2022

Drug Candidates

Open-Label Envudeucitinib Blinded Envudeucitinib Placebo Envudeucitinib Apremilast envudeucitinib A-005 ESK-001 Moxifloxacin (400 mg) Experimental drug: ESK-001
Activity Status: Slowing
Last Trial Started: 4/29/2025
Last Trial Ended: 12/18/2025
Trials (12 months): 0
Completed Trials: 8
Data sourced from ClinicalTrials.gov. This company has no FDA-approved drugs.