Arcus
Pre-Approval PRO BETAPipeline by Phase
Therapeutic Focus
Clinical Trials (29)
Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma
Started: 9/8/2025
A Clinical Trial of a New Combination Treatment, Domvanalimab and Zimberelimab, Plus Chemotherapy, for People With an Upper Gastrointestinal Tract Cancer That Cannot be Removed With Surgery That Has Spread to Other Parts of the Body
Started: 11/21/2022
Study of Quemliclustat and Chemotherapy Versus Placebo and Chemotherapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma
Started: 12/13/2024
Study Evaluating Effectiveness and Safety of Zimberelimab and Domvanalimab in Lung Cancer
Started: 2/8/2021
A Safety and Efficacy Study of Treatment Combinations With and Without Chemotherapy in Adult Participants With Advanced Upper Gastrointestinal Tract Malignancies
Started: 6/10/2022
Study to Evaluate Monotherapy and Combination Immunotherapies in Participants With PD-L1 Positive Non-small Cell Lung Cancer
Started: 5/28/2020
A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid Tumors
Started: 10/26/2022
A Study of AB801 Monotherapy and Combination Therapy in Participants With Advanced Malignancies
Started: 1/19/2024
A Study to Evaluate the Safety and Tolerability of AB680 in Participants With Gastrointestinal Malignancies
Started: 11/6/2019
Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers
Started: 10/13/2023
Metabolism, Excretion, and Mass Balance Study of Quemliclustat in Healthy Adult Participants (ARC-24)
Started: 2/3/2026
Drug-Drug Interaction Study of Casdatifan in Healthy Adult Participants (ARC-29)
Started: 5/2/2025
An Open Label Study Evaluating the Efficacy and Safety of Etrumadenant (AB928) Based Treatment Combinations in Participants With Metastatic Colorectal Cancer.
Started: 5/10/2021
A Study to Evaluate AB308 in Combination With AB122 in Participants With Advanced Malignancies
Started: 3/19/2021
Adenosine Receptor Antagonist Combination Therapy for Metastatic Castrate Resistant Prostate Cancer
Started: 7/7/2020
A Study to Evaluate the Safety and Tolerability of AB154 in Participants With Advanced Malignancies
Started: 9/12/2018
A Study to Evaluate Immunotherapy Combinations in Participants With Lung Cancer
Started: 4/1/2019
A Relative Bioavailability Study and Food Effect Study of AB521 in Healthy Adult Volunteers
Started: 8/21/2023
Study to Investigate the Safety, Tolerability, and Pharmacokinetic Profile With Oral AB521 in Healthy Volunteers
Started: 11/9/2021
Study to Evaluate Safety and Clinical Activity of AB122 in Biomarker Selected Participants With Advanced Solid Tumors
Started: 9/24/2019
A Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of AB801 in Healthy Volunteers
Started: 10/16/2023
A Study to Investigate the Pharmacokinetic Profile of Oral AB680 in Healthy Volunteers
Started: 10/20/2020
A Study to Evaluate Safety/Tolerability of Immunotherapy Combinations in Participants With Triple-Negative Breast Cancer or Gynecologic Malignancies
Started: 10/15/2018
A Study to Evaluate Pharmacokinetics (PK) of Etrumadenant Tablet and Capsule Formulations in Healthy Adult Participants
Started: 2/10/2022
A Study to Evaluate Immunotherapy Combinations in Participants With Gastrointestinal Malignancies
Started: 11/18/2018
A Study Investigating the Safety, Absorption, and Elimination of Radioactively Labeled Etrumadenant, a New Compound in the Treatment of Cancer
Started: 5/25/2022
A Study to Investigate the Safety of AB680 in Healthy Volunteers
Started: 10/16/2018
A Study to Evaluate the Safety and Tolerability of Immunotherapy Combinations in Participants With Advanced Malignancies
Started: 7/24/2018
A Drug-Drug Interaction Study to Evaluate the Effect of Itraconazole on the Pharmacokinetic Profile of Etrumadenant in Healthy Adult Participants
Started: 10/20/2021