Ascentage Pharma Group
Pre-Approval PRO BETAPipeline by Phase
Therapeutic Focus
Clinical Trials (42)
A Pivotal Study of APG-2575 (Lisaftoclax) Combined With Azacitidine in the Treatment of Acute Myeloid Leukemia
Started: 6/11/2024
Lisaftoclax (APG-2575) Combined With Azacytidine (AZA) in the Treatment of Patients With Higher-risk Myelodysplastic Syndrome (GLORA-4).
Started: 1/22/2025
Global Trial in APG2575 for Patients With CLL/SLL
Started: 12/20/2023
Study of Olverembatinib (HQP1351) in Patients With CP-CML
Started: 2/5/2024
A Study of Olverembatinib in Patients With Newly Diagnosed Ph+ ALL (POLARIS-1)
Started: 8/31/2023
A Global Study of Lisaftoclax (APG-2575) Combined With Acalabrutinib Versus Immunochemotherapy for Newly Diagnosed CLL/SLL.
Started: 4/7/2024
Study of APG-2575 in Patients With Relapsed/Refractory CLL/SLL
Started: 12/28/2021
A Study Evaluating APG-115 as a Single Agent or in Combination With APG-2575 in Subjects With R/R T-PLL and NHL
Started: 7/12/2021
A Pivotal Study of HQP1351 in Patients With Chronic Myeloid Leukemia in Chronic Phase
Started: 10/21/2019
A Study to Evaluate the Safety, Pharmacokinetics and Preliminary Efficacy of APG-5918.
Started: 3/13/2023
A Study of HQP1351 in Patients With GIST or Other Solid Tumors
Started: 7/11/2018
Pharmacokinetics of Olverembatinib in Participants With Hepatic Impairment
Started: 11/11/2025
A Study of APG-2575 in Patients With Mild-to-moderate Systemic Lupus Erythematosus.
Started: 8/9/2024
Study of HQP1351 in Subjects With Refractory CML and Ph+ ALL
Started: 1/9/2020
Study of Lisaftoclax (APG-2575) Single Agent and Combination With Therapy in Patients Relapsed/Refractory AML
Started: 9/28/2020
Study of APG2575 Single Agent and Combination Therapy in Patients With Relapsed/Refractory CLL/SLL
Started: 8/31/2020
Study of APG-2575 as a Single Agent or in Combination With Other Therapeutic Agents for CLL/SLL
Started: 3/2/2020
APG-115 in Combination With PD-1 Inhibitor in Patients With Advanced Liposarcoma or Advanced Solid Tumors
Started: 5/26/2021
APG-2449 Monotherapy or in Combination With PLD in Patients With Platinum-resistant Recurrent OC or Advanced ST
Started: 12/17/2024
APG-115 Alone or in Combination With APG-2575 in Children With Recurrent or Refractory Neuroblastoma or Solid Tumors
Started: 2/28/2023
A Phase Ib Study of APG-115 Single Agent or in Combination With Azacitidine or Cytarabine in Patients With AML and MDS.
Started: 7/6/2020
A Study of APG-3288 in Relapsed/Refractory Blood Cancers
Started: 3/1/2026
APG-1387 Plus Chemotherapy in Advanced Pancreatic Adenocarcinoma
Started: 3/17/2021
Dose-escalation Study of APG-1387 and Toripalimab in Solid Tumors
Started: 4/10/2020
A Study of APG-1252 Plus Osimertinib(AZD9291) in EGFR TKI Resistant NSCLC Patients
Started: 7/4/2019
APG-2575 Single Agent or in Combination With Ibrutinib or Rituximab in Patients With Waldenström Macroglobulinemia
Started: 5/30/2021
A Study of APG-115 in as a Monotherapy or Combination With Pembrolizumab in Patients With Metastatic Melanomas or Advanced Solid Tumors
Started: 8/29/2018
A Study of Pelcitoclax (APG-1252) in Patients With Neuroendocrine Tumors
Started: 1/6/2022
A Study to Evaluate the Safety,PK and PD of APG-2575 in Patients With Hematologic Malignancies
Started: 6/3/2019
A Study to Investigate the Safety, Tolerability, of APG-2575 as a Single Agent or in Combination for Breast Cancer
Started: 8/13/2021
The Absorption, Metabolism and Excretion of [14C]APG-2575 in Healthy Subjects
Started: 9/14/2022
APG-1387 in Patients With Advanced Solid Tumors or Hematologic Malignancies
Started: 11/21/2017
A Study of APG-1252 in Patients With Myelofibrosis Who Progressed After Initial Therapy
Started: 12/15/2020
Study of APG-1252 Plus Paclitaxel in Patients With Relapsed/Refractory Small Cell Lung Cancer
Started: 8/20/2020
APG-115 in Patients With Advanced Solid Tumors or Lymphomas
Started: 10/1/2016
A Study of APG-1252 in Patients With SCLC or Other Solid Tumors
Started: 2/12/2017
APG-1387 Study of Safety, Tolerability ,PK/PD in Patients With Chronic Hepatitis B
Started: 7/4/2018
The Absorption, Metabolism and Excretion of [14C] HQP1351 in Humans
Started: 11/19/2019
APG-1252 in Patients With SCLC or Advanced Solid Tumors
Started: 12/1/2017
Pharmacokinetics Profiles of HQP1351 Under Fasting and High-fat Meals in Patients With Chronic Myeloid Leukemia
Started: 3/25/2019