Basilea Pharmaceutica
Pre-Approval PRO BETAPipeline by Phase
Therapeutic Focus
Clinical Trials (40)
A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Patients With Invasive Mold Infections.
Started: 8/26/2025
A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Participants With Candidemia and/or Invasive Candidiasis.
Started: 12/11/2024
Late-onset Sepsis in Term and Pre-term Neonates and Infants up to 3 Months of Age
Started: 8/6/2023
Ceftobiprole in the Treatment of Patients With Staphylococcus Aureus Bacteremia
Started: 8/26/2018
Ceftobiprole in the Treatment of Pediatric Patients With Pneumonia
Started: 11/27/2017
Ceftobiprole in the Treatment of Patients With Acute Bacterial Skin and Skin Structure Infections
Started: 2/19/2018
Open-label Study of APX001 for Treatment of Patients With Invasive Mold Infections Caused by Aspergillus or Rare Molds
Started: 1/4/2020
An Open-label Study of APX001 for Treatment of Patients With Candidemia/Invasive Candidiasis Caused by Candida Auris
Started: 12/13/2019
An Efficacy and Safety Study of APX001 in Non-Neutropenic Patients With Candidemia
Started: 10/3/2018
Derazantinib in Subjects With FGFR2 Gene Fusion-, Mutation- or Amplification- Positive Inoperable or Advanced Intrahepatic Cholangiocarcinoma
Started: 9/28/2017
A Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of BAL2420 in Healthy Adult Subjects
Started: 3/4/2026
Safety and PK of Ceftibuten-ledaborbactam Etzadroxil Fixed-dose Combination
Started: 1/7/2025
A Study of Fosmanogepix in Healthy Adult Chinese Subjects
Started: 4/14/2025
Plasma and Intrapulmonary Pharmacokinetics of Ceftibuten and Ledaborbactam in Healthy Male and Female Participants 18 to ≤55 Years of Age
Started: 11/4/2024
A Clinical Trial of the Study Medicine (Called Fosmanogepix) in Participants With Varying Degrees of Hepatic Function.
Started: 10/31/2022
Ceftibuten/VNRX-7145 in Participants With Varying Degrees of Renal Function
Started: 10/12/2022
Food Effect on Ceftibuten/VNRX-7145 in Healthy Participants
Started: 9/13/2022
VNRX-7145 Drug-Drug Interaction in Healthy Adult Volunteers
Started: 6/8/2021
VNRX-7145 SAD/MAD Safety and PK in Healthy Adult Volunteers
Started: 1/20/2020
VNRX-5024 Safety and PK in Healthy Adult Volunteers
Started: 7/27/2020
Study to Assess Safety, Tolerability and Pharmacokinetics of APX001 Administered by Intravenous Infusion to Healthy Subjects
Started: 5/24/2016
Safety, Pharmacokinetics, Bioavailability, Food Effect, Drug-Drug Interaction Study of APX001 Administered Orally
Started: 10/31/2016
A Study to Assess the Effect of Ceftobiprole on the PK of Pitavastatin and on Plasma Levels of Coproporphyrin
Started: 1/17/2025
A Bioequivalence Study of APX001 High-load and Low-load Tablets
Started: 3/2/2021
Phase 1/2a Study of Oral BAL101553 in Adult Patients With Solid Tumors or Glioblastoma or High-grade Glioma
Started: 5/20/2015
Microtubule-Targeted Agent BAL101553 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma
Started: 12/15/2017
A Study to Assess the Mass Balance Recovery and Metabolite Profile & Identification of [14C]-APX001 in Healthy Males
Started: 8/17/2018
Safety and Pharmacokinetics of Intravenous and Oral APX001 in Patients With Acute Myeloid Leukemia (AML) and Neutropenia
Started: 11/27/2017
A Drug-Drug Interaction Study of CYP3A4 Inhibition and Pan-CYP Induction on APX001
Started: 11/12/2019
Derazantinib Alone or in Combination With Paclitaxel, Ramucirumab or Atezolizumab in Gastric Adenocarcinoma
Started: 10/6/2020
Derazantinib and Atezolizumab in Patients With Urothelial Cancer
Started: 8/2/2019
Phase 1/2 Study of Derazantinib (ARQ 087) in Adult Subjects With Advanced Solid Tumors With FGFR Genetic Alterations
Started: 12/10/2012
Pharmacokinetics and Safety of Ceftobiprole in Neonates and Infants up to 3 Months Treated With Systemic Antibiotics
Started: 11/22/2016
An Open-Label Study of Intravenous BAL101553 in Adult Patients With Solid Tumors
Started: 6/1/2011
Phase 1/2a Study of BAL101553 as 48-hour Infusions in Patients With Advanced Solid Tumors or Recurrent Glioblastoma
Started: 8/24/2016
Mass Balance and Pharmacokinetics Study of Derazantinib in Healthy Male Subjects
Started: 8/8/2019
Pharmacokinetic Study of the Penetration of Ceftobiprole in the Bone
Started: 4/1/2009
Open Label Study of Ceftobiprole to Evaluate Pharmacokinetics in Adults Hospitalized in the ICU
Started: 11/1/2008
Open Label Pharmacokinetic in Adult Patients With Ventilator-Associated Pneumonia
Started: 10/1/2008
Effect of Ceftobiprole on Human Intestinal Microflora
Started: 4/1/2009