Celldex
Pre-Approval PRO BETAPipeline by Phase
Therapeutic Focus
Clinical Trials (40)
Long-term Efficacy and Safety Extension (LTE) Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria
Started: 11/25/2025
A Study to Investigate Efficacy, Safety and Tolerability of Barzolvolimab Versus Placebo in Adults With Cold Induced Urticaria and Symptomatic Dermographism Inadequately Controlled by H1-antihistamines (EMBARQ - ColdU and SD)
Started: 1/15/2026
A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria (CSU)
Started: 7/19/2024
A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria
Started: 7/11/2024
Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed Glioblastoma
Started: 11/1/2011
A Study of Barzolvolimab in Patients With Atopic Dermatitis
Started: 12/18/2024
A Study of Barzolvolimab in Patients With Prurigo Nodularis
Started: 4/12/2024
A Study of CDX-0159 in Patients With Eosinophilic Esophagitis
Started: 6/1/2023
A Study of CDX-0159 in Patients With Chronic Inducible Urticaria
Started: 6/28/2022
A Phase 2 Study of CDX-0159 in Patients With Chronic Spontaneous Urticaria
Started: 5/19/2022
A Study of CDX-3379 and Cetuximab and in Patients With Advanced Head and Neck Squamous Cell Carcinoma
Started: 3/27/2018
A Study of Rindopepimut/GM-CSF in Patients With Relapsed EGFRvIII-Positive Glioblastoma
Started: 12/1/2011
A Study of the CDX-1307 Vaccine Regimen in Patients With Newly Diagnosed Muscle-Invasive Bladder Cancer (The "N-ABLE" Study)
Started: 4/1/2010
A Study of Glembatumumab Vedotin as Monotherapy or in Combination With Immunotherapies in Patients With Advanced Melanoma
Started: 11/1/2014
Study of Glembatumumab Vedotin (CDX-011) in Patients With Metastatic, gpNMB Over-Expressing, Triple Negative Breast Cancer
Started: 11/1/2013
A Study of CDX-011 (CR011-vcMMAE) in Patients With Advanced GPNMB-expressing Breast Cancer
Started: 7/1/2010
A Safety and Tolerability Study of CDX-301 With or Without Plerixafor for Stem Cell Mobilization in Matched Related Allogeneic Donor/Recipient Sibling Transplant Pairs
Started: 7/1/2014
A Study of CDX-622 in Participants With Mild to Moderate Asthma
Started: 2/1/2026
A Study of CDX-585 in Patients With Advanced Malignancies
Started: 5/11/2023
A Study of CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced Malignancies
Started: 12/1/2017
A Study of CDX-0159 in Patients With Prurigo Nodularis
Started: 11/8/2021
A Study of CDX-0159 in Patients With Chronic Spontaneous Urticaria
Started: 9/24/2020
A Study of the PD-L1xCD27 Bispecific Antibody CDX-527 in Patients With Advanced Malignancies
Started: 8/4/2020
A Single Dose Study of the Safety, Pharmacokinetics and Pharmacodynamics of CDX-0159 in Patients With Cold Contact Urticaria, Symptomatic Dermographism, or Cholinergic Urticaria
Started: 11/24/2020
A Phase 1 Study of Subcutaneous CDX-0159 in Healthy Subjects
Started: 8/30/2021
A Dose Escalation, Safety and Activity Study of CDX-014 in Patients With Renal Cell Carcinoma and Ovarian Clear Cell Carcinoma
Started: 6/1/2016
A Dose Escalation and Cohort Expansion Study of Anti-CD27 (Varlilumab) and Anti-PD-1 (Nivolumab) in Advanced Refractory Solid Tumors
Started: 1/1/2015
A Window of Opportunity Study of KTN3379 in Surgically Resectable Head and Neck Cancer Patients
Started: 10/1/2015
A Study to Evaluate the Safety and Pharmacokinetics of CDX-0158 in Adult Patients With Advanced Solid Tumors
Started: 12/1/2015
A Study of Varlilumab (Anti-CD27) and Sunitinib in Patients With Metastatic Clear Cell Renal Cell Carcinoma
Started: 5/1/2015
A Study of Varlilumab and Atezolizumab in Patients With Advanced Cancer
Started: 10/1/2015
A Study of CDX-1127 (Varlilumab) in Patients With Select Solid Tumor Types or Hematologic Cancers
Started: 10/1/2011
Enhancing Radioiodine Incorporation Into BRAF Mutant Thyroid Cancers With the Combination of Vemurafenib and KTN3379
Started: 6/1/2015
A Phase 1 Study to Evaluate the Safety and Pharmacokinetics of KTN3379 in Adult Subjects With Advanced Tumors
Started: 1/1/2014
A Study to Evaluate CDX-301 (rhuFlt3L) in Healthy Volunteers
Started: 10/1/2011
A Study of Varlilumab (Anti-CD27) and Ipilimumab and CDX-1401 in Patients With Unresectable Stage III or IV Melanoma
Started: 4/1/2015
A Study of CDX-1401 in Patients With Malignancies Known to Express NY-ESO-1
Started: 9/1/2009
Clinical Trial of CDX-1135 in Pediatric and Adult Patients With Dense Deposit Disease
Started: 1/1/2013