Dompé Farmaceutici
Pre-Approval PRO BETAPipeline by Phase
Therapeutic Focus
Clinical Trials (45)
An Efficacy and Safety Study of DFL24498 in the Treatment of AKC
Started: 12/1/2025
An Efficacy and Safety Study of Cenegermin Ophthalmic Solution Compared With Vehicle in the Treatment of PCED
Started: 4/30/2026
Efficacy and Safety of Intranasal Cenegermin in Adult Participants With Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION)
Started: 4/30/2026
Reparixin add-on Therapy to Standard Care to Limit Progression in Pts With COVID19 & Other Community Acquired Pneumonia
Started: 4/27/2022
Study to Evaluate Safety and Efficacy of Cenegermin (Oxervate®) vs Vehicle in Severe Sjogren's Dry Eye Disease
Started: 1/27/2022
Study on Efficacy and Safety of Reparixin in the Treatment of Hospitalized Patients With Severe COVID-19 Pneumonia.
Started: 2/14/2021
Safety and Efficacy Study on Cenegermin (Oxervate®) vs Vehicle in Severe Sjogren's Dry Eye Disease (PROTEGO-1 Study)
Started: 1/19/2022
A Study to Assess Efficacy and Tolerability of Ketoprofen 40 mg Granules vs Placebo
Started: 4/4/2018
Clinical Trial of Efficacy and Safety of Levopront® 30 mg/5 ml in Patients With Dry Cough
Started: 11/9/2016
Study to Assess Efficacy & Safety of Reparixin in Pancreatic Islet Transplantation
Started: 10/1/2012
An Exploratory Efficacy and Safety Study of DFL24498 Topical Ophthalmic Solution Compared With Vehicle in Participants With Dry Eye Disease
Started: 5/1/2026
A Safety and Efficacy Study of 2 Dosing Regimens of Recombinant Human Nerve Growth Factor (rhNGF) Eye Drop Solution Compared With Vehicle in Patients With Dry Eye Disease.
Started: 1/22/2024
A Study of Oral Ladarixin in Recent Onset Type 1 Diabetes and a Low Residual β-cell Function
Started: 1/12/2021
A Study to Assess Efficacy/Safety of Ladarixin in Type 1 Diabetes Patients With Preserved ß-cell Function at Baseline.
Started: 12/14/2020
Clinical Trial on Ladarixin Adjunctive Therapy to Improve Glycemic Control in Type 1 Diabetes.
Started: 9/14/2022
Pilot Study of Reparixin for Early Allograft Dysfunction Prevention in Liver Transplantation
Started: 3/10/2015
To Assess Efficacy and Safety of Oral Reparixin in Patients With Fatigue and Locally Advanced / Metastatic Breast Cancer
Started: 4/19/2022
A 8 Weeks Study to Evaluate Efficacy & Safety of rhNGF vs Vehicle in Patients After Cataract and Refractive Surgery
Started: 1/12/2017
A Study to Evaluate Safety and Efficacy of rhNGF Eye Solution vs Vehicle in Patients With Moderate to Severe Dry Eye
Started: 6/10/2019
Safety and Efficacy of rhNGF Eye Drops at Different Doses in Patients With Dry Eye
Started: 1/20/2014
A Phase 2, Multicentre, Randomized, Double-blind, Placebo-controlled Study in Patients With New-onset Type 1 Diabetes
Started: 8/1/2016
Reparixin in COVID-19 Pneumonia - Efficacy and Safety
Started: 5/5/2020
Multicenter Double Blind, Parallel-group Phase 2/3 Trial, to Study Raloxifene in Adult COVID-19 Patients.
Started: 1/22/2021
Ladarixin as Adjunctive Therapy to Improve Insulin Sensitivity and Glucometabolic Outcomes in Type 1 Diabetes
Started: 9/30/2021
Pilot Efficacy and Safety Study of Oral DF2156A in Patients With Active Bullous Pemphigoid
Started: 2/20/2012
Efficacy and Safety of Reparixin in Pancreatic Islet Auto-transplantation
Started: 2/1/2014
Evaluation of Efficacy of 20 µg/ml rhNGF New Formulation (With Anti-oxidant) in Patients With Stage 2 and 3 NK
Started: 2/1/2015
A Double-blind Study of Paclitaxel in Combination With Reparixin or Placebo for Metastatic Triple-Negative Breast Cancer
Started: 7/29/2015
Pilot Study to Evaluate Safety & Biological Effects of Orally Administered Reparixin in Early Breast Cancer
Started: 2/1/2013
An 8-week Study to Evaluate Safety and Efficacy of NGF Eye Drops Solution Versus Vehicle in Patients With Dry Eye
Started: 1/20/2017
A Study on Ketoprofen Lysine Salt (KLS) + Gabapentin (GABA) vs KLS to Investigate Their Pharmacodynamic in Healthy Males
Started: 2/8/2021
Crossover, Single Dose, Two-stage Bioequivalence Study of SCMC-Lys Salt 1.35 g Powder vs SCMC-Lys Salt 90 mg/mL Syrup
Started: 7/4/2016
Ascending Dose Tolerability Trial and PK Assessment in Healthy Volunteers After Single & Multiple Oral Intake of DF2755A
Started: 11/15/2018
Study to Evaluate Safety, Tolerability and Pharmacokinetics of rhNGF Eye Drops in Healthy Volunteers
Started: 7/1/2012
Crossover, Single Dose Randomized, Bioequivalence of Ketoprofen Lysine Salt Immediate Release vs Oral Solution
Started: 11/26/2014
Evaluation of Safety and Efficacy of rhNGF in Patients With Stage 2 and 3 Neurotrophic Keratitis.
Started: 1/1/2013
A Dose Ranging Study to Evaluate the Safety and Potential Efficacy of rhNGF in Patients With Retinitis Pigmentosa (RP)
Started: 1/1/2014
A Single Dose Study About the Influence of Food on the Oral Bioavailability of Ladarixin Capsule in Healthy Volunteers
Started: 10/20/2020
Study to Evaluate Safety, Tolerability & PK of rhNGF in Healthy Volunteers
Started: 3/30/2018
Pilot Study to Evaluate Reparixin With Weekly Paclitaxel in Patients With HER 2 Negative Metastatic Breast Cancer (MBC)
Started: 2/27/2012
Study to Evaluate Safety and Efficacy of rhNGF Eye Drops Solution Versus Vehicle in Patients With Glaucoma
Started: 12/1/2016
Study to Evaluate OXERVATE® in Patients With Stage 1 Neurotrophic Keratitis
Started: 9/9/2020
Open-label Trial to Evaluate Efficacy and Safety of rhNGF on Corneal Thickness Via AS-OCT in Neurotrophic Keratitis
Started: 4/26/2024