Grünenthal
Pre-Approval PRO BETAPipeline by Phase
Therapeutic Focus
Clinical Trials (40)
Comparison of a Single RTX-GRT7039 and Placebo Intra-articular Injection for Pain Associated With Osteoarthritis of the Knee
Started: 9/26/2022
Efficacy and Safety of RTX-GRT7039 in Adult Subjects With Knee Osteoarthritis
Started: 8/26/2022
Open-label Trial to Check the Safety and Tolerability of RTX-GRT7039 Injections for Pain Associated With Osteoarthritis of the Knee
Started: 9/15/2022
Efficacy and Safety of Intravenous Neridronic Acid in CRPS
Started: 5/30/2018
Efficacy and Safety of Intravenous Neridronic Acid in Complex Regional Pain Syndrome (CRPS)
Started: 5/31/2018
A Study to Look at Tapentadol Oral Solution in Children and Adolescents in Pain
Started: 2/19/2015
Tapentadol in Chronic Malignant Tumour Related Pain
Started: 3/1/2011
Evaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Pain Due to Osteoarthritis Taking Either WHO Step I or Step II Analgesics or no Regular Analgesic
Started: 9/1/2009
Evaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Pain Due to Osteoarthritis Taking WHO Step III Analgesics But Showing a Lack of Tolerability.
Started: 9/1/2009
Tramadol/Diclofenac Fixed-dose Combination Phase III Trial in Acute Pain After Third Molar Extraction
Started: 8/26/2017
Evaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Chronic Low Back Pain Taking Either WHO Step I or Step II Analgesics or no Regular Analgesics
Started: 9/30/2009
Evaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Chronic Low Back Pain Taking WHO Step III Analgesics But Showing a Lack of Tolerability
Started: 10/30/2009
Efficacy and Tolerability of Lidocaine Plaster for Treatment of Long-term Local Nerve Pain
Started: 10/1/2012
Pharmacokinetic, Efficacy and Safety Study of Tapentadol Oral Solution in Children With Postoperative Pain
Started: 11/1/2012
A Study to Assess the Safety and Efficacy of 7 Days Treatment With a Novel Analgesic in Subjects With Peripheral Neuropathic Pain
Started: 2/1/2012
A Trial in Painful Diabetic Peripheral Neuropathy With GRT3983Y
Started: 11/1/2009
Lidocaine 5% Medicated Plaster in Chronic Neuropathic Postoperative Pain
Started: 8/1/2010
A Study to Look at Tapentadol Tablets in Children and Adolescents in Pain
Started: 4/29/2015
Efficacy Study of a Cervical Pessary Containing Progesterone for the Prevention of Preterm Delivery
Started: 9/2/2013
Efficacy and Safety of Intravenous Neridronic Acid in CRPS-I
Started: 4/1/2015
Use of Tapentadol Oral Solution for Pain After Surgery in Children From Newborn to Less Than 2 Years Old
Started: 11/5/2014
Efficacy and Safety of EN3324 (Axomadol) in Subjects With Chronic Low Back Pain
Started: 12/1/2009
Study to Assess the Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]GRT6019
Started: 3/25/2026
A First-in-human Trial of GRT7041 in Healthy Participants
Started: 1/14/2026
A Trial to Investigate the Safety and Pharmacokinetics of GRT6019 in Healthy Male Participants
Started: 1/6/2026
A Trial to Investigate Safety and Pharmacokinetics of GRT6019, Including Food Effect, in Healthy Male Participants
Started: 11/21/2025
Intra-articular Lopain (MTX-071) Phase I/IIa Study in Chronic Osteoarthritic Knee Joint Pain
Started: 4/1/2016
Bioequivalence of Two Fixed-dose Combination Tablets Containing Estradiol and Nomegestrol Acetate
Started: 10/1/2019
A Study to Investigate Differences in the Extent and Rate of Absorption of Doxylamine/Pyridoxine From 2 Different Products Under Fasting Conditions
Started: 6/1/2019
Characterization of the Pharmacokinetics of a Vaginal Ring With 2.0 g Progesterone in Post-menopausal Women
Started: 11/1/2018
Administration of Tramadol and Ketorolac Separately and Simultaneously to Assess a Potential Pharmacokinetic Interaction
Started: 6/5/2017
Pharmacokinetic Non-interaction Study With a Fixed-dose Combination Tablet With Tramadol and Diclofenac
Started: 6/7/2015
A Comparison of How Likely it is That Different Tablets of Oxycodone Will be Broken up and Snorted by Adults Who Sometimes Take Drugs for Pleasure
Started: 7/24/2018
A Study in Healthy Male Volunteers to Investigate the Safety and Tolerability of a Single Dose of Neosaxitoxin Alone and in Combination With Bupivacaine (With and Without Epinephrine) for Brachial Plexus Blockade
Started: 1/30/2018
A Comparison of Plasma Concentrations of Hydrocodone and Acetaminophen After Administration of Different Amounts of Tablets of a New and a Marketed Tablet Formulation in Healthy Adults
Started: 9/1/2017
A Comparison of Plasma Concentrations of Hydrocodone and Acetaminophen After Administration of a New and a Marketed Tablet Formulation Under Fasted and Fed Conditions in Healthy Adults
Started: 9/1/2017
Comparison of Increasing Doses of Tapentadol Versus a Combination of Tapentadol and Pregabalin
Started: 3/1/2011
Tapentadol Prolonged Release (PR) Versus Oxycodone/Naloxone Prolonged Release in Severe Chronic Low Back Pain With a Neuropathic Component.
Started: 4/1/2013